LOCUS       DAVLHB010000001        87952 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLHB010000001 DAVLHB010000000
VERSION     DAVLHB010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 87952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.001"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            468..1754
                     /locus_tag="VXE36_000001"
     CDS             468..1754
                     /locus_tag="VXE36_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0778386.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1769..2080
                     /locus_tag="VXE36_000002"
     CDS             1769..2080
                     /locus_tag="VXE36_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778387.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            2340..3068
                     /locus_tag="VXE36_000003"
                     /pseudo
     CDS             2340..3068
                     /locus_tag="VXE36_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            3503..4294
                     /locus_tag="VXE36_000004"
     CDS             3503..4294
                     /locus_tag="VXE36_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778388.1"
                     /translation="MNFALNKGEIVGLAGRNGVGKSTWMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDWTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            4310..5038
                     /locus_tag="VXE36_000005"
     CDS             4310..5038
                     /locus_tag="VXE36_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778389.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYTLNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTIMMNTSNDLFIKAIELLPFYSLPLFVVSNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            5424..5633
                     /locus_tag="VXE36_000006"
     CDS             5424..5633
                     /locus_tag="VXE36_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0778390.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            5623..6111
                     /locus_tag="VXE36_000007"
     CDS             5623..6111
                     /locus_tag="VXE36_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778391.1"
                     /translation="MKNRFYYYQLLDEREDQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            6227..7687
                     /locus_tag="VXE36_000008"
     CDS             6227..7687
                     /locus_tag="VXE36_000008"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0778392.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            7684..8508
                     /gene="nadE"
                     /locus_tag="VXE36_000009"
     CDS             7684..8508
                     /gene="nadE"
                     /locus_tag="VXE36_000009"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0778393.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESVDAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRRLPITVFDDFWE"
     gene            8906..9457
                     /locus_tag="VXE36_000010"
     CDS             8906..9457
                     /locus_tag="VXE36_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778394.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            10172..10855
                     /locus_tag="VXE36_000011"
     CDS             10172..10855
                     /locus_tag="VXE36_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0778395.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAEQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKSQEVGEIG
                     KLLLLQSIL"
     gene            10909..11298
                     /locus_tag="VXE36_000012"
     CDS             10909..11298
                     /locus_tag="VXE36_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0778396.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(11959..12987)
                     /gene="queA"
                     /locus_tag="VXE36_000013"
     CDS             complement(11959..12987)
                     /gene="queA"
                     /locus_tag="VXE36_000013"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0778397.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            13138..13845
                     /locus_tag="VXE36_000014"
     CDS             13138..13845
                     /locus_tag="VXE36_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0778398.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            13986..14162
                     /locus_tag="VXE36_000015"
     CDS             13986..14162
                     /locus_tag="VXE36_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0778399.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            14292..15227
                     /locus_tag="VXE36_000016"
     CDS             14292..15227
                     /locus_tag="VXE36_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0778400.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            15220..16008
                     /locus_tag="VXE36_000017"
     CDS             15220..16008
                     /locus_tag="VXE36_000017"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0778401.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            16009..16392
                     /locus_tag="VXE36_000018"
     CDS             16009..16392
                     /locus_tag="VXE36_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0778402.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            16408..16797
                     /locus_tag="VXE36_000019"
     CDS             16408..16797
                     /locus_tag="VXE36_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0778403.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            16881..18011
                     /locus_tag="VXE36_000020"
     CDS             16881..18011
                     /locus_tag="VXE36_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0778404.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            18016..18753
                     /locus_tag="VXE36_000021"
     CDS             18016..18753
                     /locus_tag="VXE36_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0778405.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRCFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEELISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            18764..19537
                     /locus_tag="VXE36_000022"
     CDS             18764..19537
                     /locus_tag="VXE36_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0778406.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLTQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            19527..20144
                     /locus_tag="VXE36_000023"
     CDS             19527..20144
                     /locus_tag="VXE36_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0778407.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            20356..20757
                     /locus_tag="VXE36_000024"
     CDS             20356..20757
                     /locus_tag="VXE36_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0778408.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            20757..21035
                     /locus_tag="VXE36_000025"
     CDS             20757..21035
                     /locus_tag="VXE36_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0778409.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            21025..21798
                     /locus_tag="VXE36_000026"
     CDS             21025..21798
                     /locus_tag="VXE36_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0778410.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCRNDKPLAPFQAKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYVTYLQPWDYAAASILGESLGY
                     RVVTLSGEAPDFQTRQPVMMLPLEMQEEIQSYIYERKRT"
     gene            21799..23103
                     /locus_tag="VXE36_000027"
     CDS             21799..23103
                     /locus_tag="VXE36_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0778411.1"
                     /translation="MQFPEGFVEKYEEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AYLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            23677..24555
                     /gene="pstS"
                     /locus_tag="VXE36_000028"
     CDS             23677..24555
                     /gene="pstS"
                     /locus_tag="VXE36_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0778412.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            24555..25472
                     /gene="pstC"
                     /locus_tag="VXE36_000029"
     CDS             24555..25472
                     /gene="pstC"
                     /locus_tag="VXE36_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0778413.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGIWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            25462..26346
                     /gene="pstA"
                     /locus_tag="VXE36_000030"
     CDS             25462..26346
                     /gene="pstA"
                     /locus_tag="VXE36_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0778414.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            26357..27160
                     /gene="pstB"
                     /locus_tag="VXE36_000031"
     CDS             26357..27160
                     /gene="pstB"
                     /locus_tag="VXE36_000031"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0778415.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            27173..27931
                     /gene="pstB"
                     /locus_tag="VXE36_000032"
     CDS             27173..27931
                     /gene="pstB"
                     /locus_tag="VXE36_000032"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0778416.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            27943..28596
                     /gene="phoU"
                     /locus_tag="VXE36_000033"
     CDS             27943..28596
                     /gene="phoU"
                     /locus_tag="VXE36_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0778417.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            28753..29568
                     /locus_tag="VXE36_000034"
     CDS             28753..29568
                     /locus_tag="VXE36_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0778418.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(29588..30859)
                     /locus_tag="VXE36_000035"
     CDS             complement(29588..30859)
                     /locus_tag="VXE36_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0778419.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            31001..31732
                     /gene="budA"
                     /locus_tag="VXE36_000036"
     CDS             31001..31732
                     /gene="budA"
                     /locus_tag="VXE36_000036"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0778420.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIGEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            31742..32494
                     /locus_tag="VXE36_000037"
     CDS             31742..32494
                     /locus_tag="VXE36_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0778421.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            32606..33511
                     /gene="murB"
                     /locus_tag="VXE36_000038"
     CDS             32606..33511
                     /gene="murB"
                     /locus_tag="VXE36_000038"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0778422.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            33672..34829
                     /locus_tag="VXE36_000039"
     CDS             33672..34829
                     /locus_tag="VXE36_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778423.1"
                     /translation="MKKSIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            34810..35616
                     /locus_tag="VXE36_000040"
     CDS             34810..35616
                     /locus_tag="VXE36_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778424.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            35613..36386
                     /locus_tag="VXE36_000041"
     CDS             35613..36386
                     /locus_tag="VXE36_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778425.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            36383..37453
                     /locus_tag="VXE36_000042"
     CDS             36383..37453
                     /locus_tag="VXE36_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0778426.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            37698..37937
                     /locus_tag="VXE36_000043"
     CDS             37698..37937
                     /locus_tag="VXE36_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778427.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            38212..38697
                     /locus_tag="VXE36_000044"
     CDS             38212..38697
                     /locus_tag="VXE36_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0778428.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            38719..41337
                     /gene="alaS"
                     /locus_tag="VXE36_000045"
     CDS             38719..41337
                     /gene="alaS"
                     /locus_tag="VXE36_000045"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0778429.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(41427..42881)
                     /locus_tag="VXE36_000046"
     CDS             complement(41427..42881)
                     /locus_tag="VXE36_000046"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0778430.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNNYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            43060..43809
                     /locus_tag="VXE36_000047"
     CDS             43060..43809
                     /locus_tag="VXE36_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778431.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            43790..45424
                     /locus_tag="VXE36_000048"
     CDS             43790..45424
                     /locus_tag="VXE36_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778432.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENLDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            46109..47272
                     /locus_tag="VXE36_000049"
     CDS             46109..47272
                     /locus_tag="VXE36_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0778433.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            47269..47946
                     /locus_tag="VXE36_000050"
     CDS             47269..47946
                     /locus_tag="VXE36_000050"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0778434.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            47936..48790
                     /locus_tag="VXE36_000051"
     CDS             47936..48790
                     /locus_tag="VXE36_000051"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0778435.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            48809..49876
                     /locus_tag="VXE36_000052"
     CDS             48809..49876
                     /locus_tag="VXE36_000052"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0778436.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            49886..51052
                     /gene="aroC"
                     /locus_tag="VXE36_000053"
     CDS             49886..51052
                     /gene="aroC"
                     /locus_tag="VXE36_000053"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0778437.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            51062..52165
                     /locus_tag="VXE36_000054"
     CDS             51062..52165
                     /locus_tag="VXE36_000054"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0778438.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            52176..52514
                     /locus_tag="VXE36_000055"
     CDS             52176..52514
                     /locus_tag="VXE36_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0778439.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            52606..53889
                     /gene="aroA"
                     /locus_tag="VXE36_000056"
     CDS             52606..53889
                     /gene="aroA"
                     /locus_tag="VXE36_000056"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0778440.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGASVIIEKECTRNHTEDMLKQFGGHLSVDSKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            53882..54358
                     /locus_tag="VXE36_000057"
     CDS             53882..54358
                     /locus_tag="VXE36_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0778441.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            54355..55203
                     /gene="pheA"
                     /locus_tag="VXE36_000058"
     CDS             54355..55203
                     /gene="pheA"
                     /locus_tag="VXE36_000058"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0778442.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAENPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLAHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            55200..56474
                     /gene="psr"
                     /locus_tag="VXE36_000059"
     CDS             55200..56474
                     /gene="psr"
                     /locus_tag="VXE36_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0778443.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            56753..57598
                     /locus_tag="VXE36_000060"
     CDS             56753..57598
                     /locus_tag="VXE36_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0778444.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSCILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDTVIADMDKSYTEYK
                     GEYGG"
     gene            57588..58691
                     /locus_tag="VXE36_000061"
     CDS             57588..58691
                     /locus_tag="VXE36_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0778445.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            58693..59679
                     /locus_tag="VXE36_000062"
     CDS             58693..59679
                     /locus_tag="VXE36_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0778446.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVVFFRLAYAHFFILDKMLLDDQYKQFKAYS
                     QIHRFLKDHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            59695..61128
                     /locus_tag="VXE36_000063"
     CDS             59695..61128
                     /locus_tag="VXE36_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0778447.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            61157..62191
                     /locus_tag="VXE36_000064"
     CDS             61157..62191
                     /locus_tag="VXE36_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0778448.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            62391..63128
                     /gene="mecA"
                     /locus_tag="VXE36_000065"
     CDS             62391..63128
                     /gene="mecA"
                     /locus_tag="VXE36_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0778449.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            63279..64565
                     /locus_tag="VXE36_000066"
     CDS             63279..64565
                     /locus_tag="VXE36_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0778450.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITCALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            64567..65436
                     /locus_tag="VXE36_000067"
     CDS             64567..65436
                     /locus_tag="VXE36_000067"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0778451.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            65512..65583
                     /locus_tag="VXE36_000068"
                     /pseudo
     CDS             65512..65583
                     /locus_tag="VXE36_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            65731..66669
                     /gene="msrB"
                     /locus_tag="VXE36_000069"
     CDS             65731..66669
                     /gene="msrB"
                     /locus_tag="VXE36_000069"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0778452.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            66727..68451
                     /locus_tag="VXE36_000070"
     CDS             66727..68451
                     /locus_tag="VXE36_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778453.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            68453..70201
                     /locus_tag="VXE36_000071"
     CDS             68453..70201
                     /locus_tag="VXE36_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778454.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            70593..71852
                     /locus_tag="VXE36_000072"
     CDS             70593..71852
                     /locus_tag="VXE36_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0778455.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    71928..72063
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            72102..72602
                     /locus_tag="VXE36_000073"
     CDS             72102..72602
                     /locus_tag="VXE36_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0778456.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNNFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            72678..73046
                     /gene="rplL"
                     /locus_tag="VXE36_000074"
     CDS             72678..73046
                     /gene="rplL"
                     /locus_tag="VXE36_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0778457.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            73247..73420
                     /locus_tag="VXE36_000075"
     CDS             73247..73420
                     /locus_tag="VXE36_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778458.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQS"
     gene            73417..73665
                     /locus_tag="VXE36_000076"
                     /pseudo
     CDS             73417..73665
                     /locus_tag="VXE36_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            73679..74002
                     /locus_tag="VXE36_000077"
                     /pseudo
     CDS             73679..74002
                     /locus_tag="VXE36_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            73995..74375
                     /locus_tag="VXE36_000078"
     CDS             73995..74375
                     /locus_tag="VXE36_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0778459.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            74388..74531
                     /locus_tag="VXE36_000079"
     CDS             74388..74531
                     /locus_tag="VXE36_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778460.1"
                     /translation="MAERFWENLSIILAERNISCIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            74624..75211
                     /locus_tag="VXE36_000080"
     CDS             74624..75211
                     /locus_tag="VXE36_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0778461.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
     gene            75610..76419
                     /locus_tag="VXE36_000081"
     CDS             75610..76419
                     /locus_tag="VXE36_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0778462.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            76424..77125
                     /locus_tag="VXE36_000082"
     CDS             76424..77125
                     /locus_tag="VXE36_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0778463.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            77150..78067
                     /locus_tag="VXE36_000083"
     CDS             77150..78067
                     /locus_tag="VXE36_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV0778464.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            78095..79636
                     /locus_tag="VXE36_000084"
     CDS             78095..79636
                     /locus_tag="VXE36_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV0778465.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            79655..80113
                     /locus_tag="VXE36_000085"
     CDS             79655..80113
                     /locus_tag="VXE36_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0778466.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            80115..82337
                     /locus_tag="VXE36_000086"
     CDS             80115..82337
                     /locus_tag="VXE36_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV0778467.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            82377..83486
                     /locus_tag="VXE36_000087"
     CDS             82377..83486
                     /locus_tag="VXE36_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0778468.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            83643..84533
                     /locus_tag="VXE36_000088"
     CDS             83643..84533
                     /locus_tag="VXE36_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0778469.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            84558..84881
                     /locus_tag="VXE36_000089"
     CDS             84558..84881
                     /locus_tag="VXE36_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778470.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            84871..86862
                     /locus_tag="VXE36_000090"
     CDS             84871..86862
                     /locus_tag="VXE36_000090"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV0778471.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            86878..87354
                     /locus_tag="VXE36_000091"
     CDS             86878..87354
                     /locus_tag="VXE36_000091"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV0778472.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            87388..>87952
                     /locus_tag="VXE36_000092"
     CDS             87388..>87952
                     /locus_tag="VXE36_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778473.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIAN"
BASE COUNT        26448 a        15647 c        19309 g        26548 t
ORIGIN      
        1 gcttttttct ttttaaatat tgattgtttc taaaagttct agtaatattg ctatttctca
       61 tttttccaaa tatgttattc aacttattag ctacgtctct attcatattt gggtataaaa
      121 caaaaaatca attctaacag ttttatatca gaataataaa taaaaaagcg atattctaga
      181 ctgtatcaat ccttttccat tataggagca acagagtggg agtagtcatc taaggactaa
      241 tttatgtatt tttacgagtc agtatctttg gatactggtt tttacttttc tagacttttt
      301 gactacttgt taaaactggg ataattttcg actgtttaac agttattatg caaagtctaa
      361 aagattagaa ttgtcaaaac aatccgtcta ggcttgattt tatcctttat ttactataaa
      421 atgagaagga aaaatgtcaa acttttatat tgcaaatagg agaaattatg acaaaaacat
      481 taaaacgtcc tgaggtttta tcacctgcag ggactttaga gaagctaaag gtagctgttc
      541 agtatggagc agatgctgtc tttatcggtg gtcaggccta tggtcttcgt agccgtgccg
      601 gaaactttac tttcgaacag atggaagaag gcgtgcagtt tgcggccaag tatggtgcca
      661 aggtctatgt agcggctaat atggttatgc acgaaggaaa tgaagctggt gctggtgagt
      721 ggttccgtaa actgcgtgat atcgggattg cagcagttat cgtatctgac ccagccttga
      781 ttatgattgc agctactgaa gcaccaggcc ttgaaatcca cctttctacc caagccagtg
      841 ccactaacta tgaaaccctt gagttctgga aagagctagg cttgactcgt gtcgttttag
      901 cgcgtgaggt ttcaatggaa gaattagctg aaatccgcaa acgtacagat gttgaaattg
      961 aagcctttgt ccatggagct atgtgtattt catactctgg acgttgtact ctttcaaacc
     1021 acatgagtat gcgtgatgcc aaccgtggtg gatgttctca gtcatgccgt tggaaatacg
     1081 acctttacga tatgccattt gggaaagaac gtaagagttt gcagggtgag attccagaag
     1141 aattttcaat gtcagccgtt gacatgtcta tgattgacca cattccagat atgattgaaa
     1201 atggtgtgga cagtctaaaa atcgaaggac gtatgaagtc tattcactac gtatcaacag
     1261 taaccaactg ctacaaggcg gctgtggatg cctatcttga aagtcctgaa aagtttgaag
     1321 ctatcaaaca agacttggtg gacgagatgt ggaaggttgc ccaacgtgaa ttggcaacag
     1381 gtttctacta cggtatacca tctgaaaatg agcagttgtt tggtgctcgc cgtaaaattc
     1441 ctgagtacaa gtttgtcgct gaagtggttt cttatgatga tgcggtacaa acagcaacca
     1501 ttcgtcaacg aaacgtcatt aacgaagggg accaagttga gttttatggt ccaggtttcc
     1561 gtcattttga aacctatatt gaagatttgc atgatgccaa aggcaataaa atcgaccgcg
     1621 ctccaaatcc aatggaacta ttgactatta aagtcccaca acccgttcaa tcaggagaca
     1681 tggttcgtgc attaaaagaa ggactcatca atttttataa ggaagatgga accagcgtca
     1741 cagttcgagc ttaagaaagg aaaaggaaat gatagaggca cagggtttct tagtggataa
     1801 gcaaacaaga tgcattcatt accatagcaa gctggatatt attgctttac aatgctatga
     1861 ttgtaaaaag tattatgctt gttatcggtg tcatgattca ttagaaaatc acccttttga
     1921 gccttatccc ttatctttga tacaggataa gcctatttta tgtggtgttt gtctaaaact
     1981 attaacatat aagcaatata aagaaagctt aagttgcctc ttttgttttt ctcgctttaa
     2041 tccaggttgc caaaatcata aggaacgcta ttttaaatag caaatcatct agttttgaag
     2101 taggagaaaa ctcaattcca agagaaaatg aagtaaatct tcccacaata aaacgcataa
     2161 tatcaagatt gttcaatacc tgatactatg cgtttttaag attttaaaga cttttttcct
     2221 agcccctttt tactttatct ggtattttga ctacttgtta aaactggggt aattttcgac
     2281 tgtttaacag ttattatgca aagtctaaaa ggttagaatt gtcaaaacaa tccgtctaga
     2341 gtatgcgtga tgccaactgt ggtggatgtt ctcagtcatg ccgctggaag tacgaccttt
     2401 acgatatgcc atttgggaaa gaacgtaaga gtttgcaggg tgagattcca gaagaatttt
     2461 caatgtcagc cgttgatatg tctatgattg accatatctc agatatgatt gaaaatggtg
     2521 tggacagtct aaaaatcgaa ggacgtatgg agtctattca ctatgtatca acagtaacca
     2581 actgctacaa ggcggctgtg gatgcctatc ttgaaagtcc tgaaaagttt gaagctatca
     2641 aacaagactt ggtggacgag atgtggaagg ttgcccaacg tgaactggct acaggatttt
     2701 actatggtac accatctgaa aatgagcagt tgtttggtgc tcgtcgtaaa atccctgagt
     2761 acaagtttgt cgctgaagtg gtttcttatg atgatgcggc acaaacagca actattcgtc
     2821 aacgaaacgt cattaacgaa ggggaccaag ttgagtttta tggtccaggt ttccgtcatt
     2881 ttgaaaccta tattgaagat ttgcatgatg ccaaaggcaa taaaatcgac cgcgctccaa
     2941 atccaatgga actattgact attaaagtcc cacaacctgt tcaagctgga gacatggttc
     3001 gagctcttaa agaggggctt atcaatcttt ataaggaaga tggaaccagc gtcacagttc
     3061 gtgcttaatg tagttgttta gttttaaaaa attatgcaaa gctccatata caacacttaa
     3121 acgagattaa agaatggcga aatcccttga tgcgcaagag attagctgtc ttttttattt
     3181 tttaagtgat aaagtcggag cttaggtatt aaagcctatc aaattaaaca aagaagcgat
     3241 gtcttagata ttttgaaaaa aattaataag cagaaaactc tctattattt tgttgtagag
     3301 agttttttgt taataaaatt ttacaaaatg acatttatat attgcattaa gttagatata
     3361 tgatataata ttgttaaaaa gaggtgcaac tttttaaact caataagaat caaagagcaa
     3421 accatgaata ttaatggagg aataaaaaat gtaagttata aatgtaagta agcattatgg
     3481 ttattcaatc attctcaaag atataaattt tgcacttaac aagggtgaaa ttgttggtct
     3541 agcagggaga aatggagttg gtaagagtac gtggatgaaa attcttgttc agaataatca
     3601 accgacttca ggtaatatta taagcagtga taatgttggg tatttaatcg aagaaccaaa
     3661 attattttta tctaaaacag gtttagagaa tttaaaatat ttgtcaaatt tatatggtgt
     3721 tgactacaat caagaaagat ttagaagttt gatccaagag ttagattgga ctcagtctat
     3781 taataaaaaa gtaaagacct attctttggg tacaaaacaa aaattagctt tgcttctaac
     3841 tctcgttacg gaacctgata tattgatttt agatgaaccg actaatggtt tagatattga
     3901 atcatcacaa atagttttat cggttctaaa aaatttagct ttacatgaaa atgtgggaat
     3961 tttaatatcg agtcataaat tagaagacat tgaagaaatt tgtgagaggg ttcttttctt
     4021 ggagaacggg cttttgacat ttcaaaaagt aggaaaagat agtcataatt tcttgtttga
     4081 gatagctttt tcatcagcta cagatagaga cattttcatt accaaacaag aatttgggga
     4141 tattgttcag gaagagggac tgagaattac tatgtctggg aatattcaaa gtagtgagct
     4201 ttttaaattt tttaacgaaa actctattaa agtagttgat tttgaaacta aaaaagagac
     4261 gcttaaagat atttatctaa atcgttcaaa ataaaggaag gttataatca tgaaattaaa
     4321 taaattgaat tttcttaagg aaaatataag aaatttatat tcatcaggcg taatatatct
     4381 cggtttgctt atatcgttta taccgccgat attggttaca ttctttattc taaagactca
     4441 agggacatcg cttggtatta agcatatttc aaacttttat gctatgctcg gtatgttaat
     4501 ggctgttata catgctaatc gagtcattag tagagatttt tcccacaata cggtaagttt
     4561 gttttataat caacagaaga atcggatgat ttacgtcttg tctaattttc tatatgccat
     4621 ctcagtttcc attatttata ctttgaatgg cattgtgtta ctagtcatag taagtaaatt
     4681 gggtattcca ggtgatttag gattagattt tatagtagct attgtagtca atacaatttt
     4741 gttagtcctg ttttattttc tattatctta cattttctat ttatacaaat tgaaaagtgg
     4801 cttggtattt ggtattttag tagctttact actctttatc cctaatatat taaatacgat
     4861 tatgatgaat actagtaatg atttgtttat caaagcaatt gaacttcttc ctttttattc
     4921 tttacctcta tttgtggttt caaatacgat gtctattagt cagtatcttg tgctaatcac
     4981 tacaatcatt ttattgtact ttttcactct caagaaaagc aagaagtatt cattttagtt
     5041 tcatttagta ttattttgca tacctaaaat acagtaaaaa aatcagtcat cttggtatgc
     5101 tcctgctttc actattcaac acgtttttga cttatactag gctcatttcc agaagcatta
     5161 tataatagtg atatgaaacc aactaaacta aacaagaaat ataagcaata aaaactcgtt
     5221 taaaagattc tactaaagct aatactaaat aaaaataaaa gagtaaacta ggaagtttat
     5281 ttcaaacaac ctaaaatact gattttcgtc tgaagataat actggagtgc aaattaatgg
     5341 ggttataata aatagctgat agcttgtgtt ggttttggat tttttaagag tagatgagta
     5401 ttaaaactat aaggaggacg aaggtggcta aaaatttaaa attaaaatta gctcgggtag
     5461 agcgtgattt aacacaaggt caactggcag aggctgtcgg ggtgacacgc cagactattg
     5521 gtttgataga ggcgggaaaa tacaatccca gtctctcgct ctgccagtct atttgcagat
     5581 gtttagggaa aaccctagac caactatttt gggaggaaga agatgaaaaa tagattttat
     5641 tattatcaat tactagacga aagagaagac caactgttca ataaagcggg atctgaaagt
     5701 ttctatatct gcattgcttt gtcgctccta tcttatatca tttcagtatt agcaccaagc
     5761 ctttttaatt ctaatatgct gctaatcgtt atcatcatag ggacatttta ctttttcaat
     5821 cgcgcccgtt atctgggagt gacctactat agtcgttttc attttacgat tttgggttgt
     5881 tttttcctaa ccttggctat tacggctctt ttgatgttgc agaattatca attcaacata
     5941 gaaatttatc agcacaatcc tttgaatttt aaatacctgt ctgcttgggt cattacttat
     6001 gtcatttacc ttccgtgggt ctttattggc aatcttggtc ttaagagcta tggcgaatgg
     6061 gctcagaaaa aatttgaaca agatatggat gaattggaga gtggagaata gcttgttact
     6121 cttttctcaa tccagctaaa atgtgatata atagtactaa tttattggaa tacatgaaag
     6181 ttcttgaaaa ttttcatggg tttctagcta aggaagtagg aaaagtatgt atccagatga
     6241 tagtttgaca ttgcacacgg acttgtacca gatcaacatg atgcaggttt actttgacca
     6301 agggattcac aataagaagg cggtctttga ggtgtatttc cgccaacagc cttttaagaa
     6361 cggctatgcg gtttttgcag gtttggaaag aattgtgaac tatcttgaag acttgcgttt
     6421 ttcagatagt gatatagcct atttggagtc gcttggttat catggggcgt tcttggatta
     6481 ccttcgcaat ttcaagttgg agttgaccgt tcgttctgcc caagaagggg atttggtttt
     6541 tgctaatgaa ccgattgtgc aggtggaagg acctctagcc caatgtcagt tggtcgaaac
     6601 ggctcttttg aacatcgtca actaccagac cttggtggcg acgaaggcag ctcgtattcg
     6661 ttcggttatc gaagatgaac ccttgatgga gtttgggaca cgtcgggctc aagaaatgga
     6721 tgcggccatc tggggaacac gcgcagcggt gattggtggg gccaatggaa ccagcaacgt
     6781 gcgtgcgggt aagctctttg acattcctgt tttgggaacc catgcccatg ccttggtaca
     6841 ggtttatgga aatgactatg aagctttcaa ggcttacgct gcgacccaca aaaattgtgt
     6901 ctttcttgtg gatacctatg acacccttcg catcggtgta ccagctgcca ttcaggtggc
     6961 gcgtgagctg ggtgatcaga ttaactttat gggtgtgcgg attgactctg gggatattgc
     7021 ctacatttct aagaaagtcc gtcagcaact ggacgaggct ggatttacag aggctaagat
     7081 ttatgcttct aatgatttgg acgaaaatac tatcctcaat ctcaagatgc aaaaggccaa
     7141 gattgatgtc tggggcgtgg gtaccaagct gattacagct tatgaccagc cagctcttgg
     7201 tgcagtttac aagattgttg caatcgaaga tgaaactggt cagatgcgca atacgattaa
     7261 gctgtctaat aatgctgaaa aagtttctac gccaggtaag aagcaggtgt ggcgcattac
     7321 cagtcgtgaa aaaggcaagt cagaaggcga ctatatcact tatgatggtg tggatattag
     7381 cgacatgaca gaaatcaaga tgttccatcc gacctataca tacatcaaga agacggttcg
     7441 taattttgat gccgttcctc tcttggtgga tatcttcaaa gaaggaatat tagtttacaa
     7501 cttgcctagt ttgactgaca ttcaggatta tgcccgtaag gaatttgaca agttgtggga
     7561 tgagtataag cgtgtgctca atccgcagca ctatccagtg gatttggcgc gtgatgtatg
     7621 gcaagataag atggacttga ttgataagat gcgcaaggaa gcccttggtg aaggagaaga
     7681 agaatgagtt tgcaagaaac gattatccaa gagctgggtg tcaaaccagt gattgatgcc
     7741 caggaagaaa tccgtcgttc tattgatttc ttaaaaagat atctgaaaaa acatcccttc
     7801 ctaaaaacct ttgtactagg gatttctggg ggacaagact caaccttggc aggacgtttg
     7861 gcgcaattag ctatggaaga actgcgagct gaaacgggag acgatagcta caaatttatc
     7921 gctgtccgcc tgccatacgg agtgcaagct gatgaagcag atgctcaaaa agccctagcc
     7981 ttcatccagc cagatgtcag cttggttgtg aatatcaagg aatcagttga tgccatgaca
     8041 gctgcagttg aagcgacagg tagtcctgtt tcagacttca acaaggggaa tatcaaggca
     8101 cgttgccgta tgattgctca gtatgccctt gctggttccc atagcggagc ggtcattgga
     8161 acagaccacg ccgcggaaaa tatcacaggt ttctttacca agtttggtga cggcggtgcg
     8221 gatattctcc ctctttaccg cctcaataaa cgccaaggaa aacagctctt gcagaaactt
     8281 ggcgcagagc cagcccttta tgaaaaaatc ccaacggcag acctagaaga agataaacca
     8341 ggcctagctg acgaagtcgc acttggagtc acctacgcag agattgacga ctacctagaa
     8401 ggcaaaacaa tcagcccaga agctcaagcg accattgaaa actggtggca caaaggccaa
     8461 cacaaacgcc gcttacccat cactgtattt gatgactttt gggagtaaaa acctccattg
     8521 gaggttttta ccctgagcct agaaatgaga aagcgaagaa ggtccggggg actttttagc
     8581 ttcttgccct gaaattaaaa agcaagaaaa acctccactg gaggttttca gcctctcatc
     8641 ttgaaataag aaagtgagag aaggtctggg ggatcttgaa ccccgagttt agaaataaga
     8701 aaatgaggca gattcagtaa ctcgaagagt tcgatttcat cgtcttaccc ctgcaacgat
     8761 gactaggttt gaaaaagctt gctagagcgc atttcaaacc aggcagcaac tgcgtcaaga
     8821 aattagaaga caaactcgtt ttctagctgt tactgagttg agccttttta ctacgagtat
     8881 agaaataagg aagtgaggta gcatcatgaa atctatcggt acgcaaatat tacagacaga
     8941 acgtttgatt ttaagaagat ttgtggagag tgatgcagaa gccatgtttc aaaattgggc
     9001 ttcatccgct gagaatctga cctatgttac ctgggatccc catcctgatg tcgaaatcac
     9061 tcgaaactcg atttgcaatt gggttgcttc ctatactaat ctcaactatt ataaatgggc
     9121 catttgtcta aaagaaaacc cagagcaagt gataggagat atcagcattg ttaagataga
     9181 cgaggctgat ttaagctgtg aaattggcta tgtgttaggc aaggcttact ggggaaatgg
     9241 tatgatgaca gagactttga aagctatctt ggacttttgt tttactcaag caggttttca
     9301 aaaggtcaga gcacgttatg ccagtctcaa cccagcttca ggtcgtgtca tggaaaaggc
     9361 tggaatgtcc tatctacaaa ccattgttaa tggtgtagag agaaaaggct atcttgcgga
     9421 tcttatttat tatggtataa gtagggaaga atgttgaatt ctattttctg tttctatcga
     9481 agtcaactat ttattgtaaa tataataatt agcattccaa gtttatttga aactttaaaa
     9541 tagcatattg attagtacaa gacagatgtt ctagttcctt ctttaatctg gtttagtgtt
     9601 agttaaaaaa tcgctttaag cttgtaacta agagggagct aatcgactag attctccagc
     9661 cgaacaggtg gtaatgtact ttttatagtg taatcctagc tgttgttaaa tttaaaatag
     9721 aatcctctat cgagttaggg aattaaattc aaccaatttt attcatgttt tttctatcaa
     9781 attatctaat attaaaatag tctcattctg atgagaaaac tattctattt atactgcata
     9841 gttgtataag gaatgatgaa agatgagtga aaattatcaa gttggaatgt ttgtatctaa
     9901 atatattagc atgtatttag ataagatgtc tgcaatcctt tatatatgag attgattacg
     9961 atatagttaa agtgttagtt caataatcaa tatatcattc taagtctatt ttatatataa
    10021 agtatattgt ttaacgtttg atagaaaaga tgctatacta gaagtaggat gtaatggcaa
    10081 aatctaatac taataagcgc tatgcaatac gtaaactcgg aaagattttt ggttctgcgg
    10141 taatcgggct aactttattt ttaggaggaa tctgaataca agttttgttc atgctgctga
    10201 tgggattcaa tatgtcagag atgatactag agataaagaa gagggaatag agtatgatga
    10261 cgctgacaat ggggatatta ttgtaaaagt agcgactaaa cctaaggtag taaccaagaa
    10321 aatttcaagt acgcgaattc gttatgaaaa agatgaaaca aaagaccgta gtgaaaatcc
    10381 tgttacaatt gatggagagg atggctatgt aactacgaca aggacctacg atgttaatcc
    10441 agagactggt tatgttaccg aacaggttac tgttgataga aaagaagcca cggatacagt
    10501 tatcaaagtt ccagctaaaa gcaaggttga agaagttctt gttccatttg ctactaaata
    10561 tgaagcagac aatgaccttt ctgcagaaca ggagcaagag attactctag gaaagaatgg
    10621 gaaaacagtt acaacgataa cttataatgt agatggaaag agtggacaag taactgagag
    10681 tactttaagt caaaaaaaag actctcaaac aagagttgtt aaaaaaggaa ccaagcccca
    10741 agttcttgtc caagaaattc caatcgaaac agaatatctc gatggcccaa ctcttgataa
    10801 aagtcaagaa gtaggagaaa ttggtaaatt actcttacta caatctatac tgtagatgaa
    10861 cgtgatggaa caattgaaga aactacttct cgtcaaatta ctaaagagat ggtaaaaaga
    10921 cgtataagga gagggacgag agaacctgaa aaagttgttg ttcctgagca atcatctatt
    10981 ccttcgtatc ctgtatctgt tacatctaac caaggaacag atgtagcagt agaaccagct
    11041 aaagcagttg ctccaacaac agactggaaa caagaaaatg gtatgtggta tttttataat
    11101 actgatggtt ccatggcaac aggttgggta caagttaatg gttcatggta ctacctcaac
    11161 agcaacggtt ctatgaaagt caatcaatgg ttccaagttg gtggtaaatg gtattatgta
    11221 aatgcatcgg gtgagttagc ggtcaataca agtatagatg gctatagagt caatgataat
    11281 ggtgaatggg tgcgttaaca gattcctccc tgcgacaaaa ttgataatag tatgtctgaa
    11341 tatataatta tatataaaaa gccatagata aggtcatctt atagcgacta taaaaaagtg
    11401 aacaagccta gtcttctgta cattagaatt cagatttgtt cactttttgt ttaatactca
    11461 atgaaaatca aagagcaaac tagaaaacta gtcgcaggtt gctcaaagta ctgctttgag
    11521 gttgtagata gaactgacga agtcagtcac atatataatc caaggtgacg ttgacgcggt
    11581 ttgaagagat ttttgaagag tataagtctt tgattttgag actaaggaga gtcagggtca
    11641 aagtagtgaa tgattctgaa ataactcata atagtctctt gagaggacag ataagagtaa
    11701 caaatatggt gctactcatg tgtcttgcat tttgatttac aaacagcgaa gaaaatatag
    11761 gaagctgaaa taaaatatag atgaatcaat ttggagagtc aacgcaatct atggcaatat
    11821 tttcgaagct agggggaagc attttaattt caatgtacta ggcgtcttct acagctagct
    11881 agagtttcaa ttgtagatgt tctttgaaat aatatcttag cgatttattg gtattagaag
    11941 atttagagaa attctttctc aataaataaa catggagtca ccaaaactga agaagcggta
    12001 gtgttcttgg atggcatggt ggtaggcatc taagactaat tcacggcctg caaaggcaga
    12061 aaccaacatg accagagttg attttggcag atggaagttg gttgagaagg catccacgac
    12121 cttccactca tacccaggtt tgataaagat attggtccaa ccagaatctg cttggatttg
    12181 cccatcaaac ttggaaccaa tagtttccaa ggtgcggata gaagtggttc cgacagcgat
    12241 gacacgacca ccattttttt tgacagagcg aagggtggca gcagcttcct cagaaagttg
    12301 atagaactct gagtgcattt cgtgttcgtc cagattatcc acagaaacag gtctaaaggt
    12361 tccgagtccg acatggagag tcagatagac tagatgaaca cccttagctt ggatttctgc
    12421 cagcagttct ttggtgaagt gaagaccagc agtcggtgct gcagcagagc cgctttcctt
    12481 ggcgtagacg gtttgataac gttcacggtc atctaatttt tcgtggatat aaggtggcag
    12541 aggcatttct cccagacttt ccaagacttc taggaaaatt ccttggtatt caaagcggac
    12601 aatgcgtccc ccgtgggtca attcttctgt aacgacagcg ctgaggcggc catcaccaaa
    12661 gctgatacga gtaccgacct tgaggcgttt ggcaggttta gccagaactt cccactcgtc
    12721 tccactagtg ttcttaagga ggagaagttc cacatgacct cctgtctcca ctttttgacc
    12781 atagaggcgg gcagggagaa ctcgggtgtc gttcatgaca agggcatcac caggttccag
    12841 catatcaata atagagtgga agtgtttatc ttgcatttct cctgtctcac ggttgacgat
    12901 gaggagtttg gaggcatcac gtttttcaag gggcgtttgg gcaatcaatt cctctggcaa
    12961 gtggaaatca aaatcagctg tattcatata tctgttcatt ctttctaagt tctaatccta
    13021 tccattataa cacgtttcaa gtttggacgc tcttttttta gaaattaaat cgttttcact
    13081 tgacaaaaat tggtctatac catataataa atatagacag aaatggagga tgaaaagatg
    13141 aaagttatta aagttgaaaa ccaagttcaa ggtggaaaag ttgcttttga gattttgaag
    13201 gaaaaattgg ctaatggagc tcaaactcta ggacttgcga caggaagtag cccacttgaa
    13261 ttttacaagg aaattgttga gagtgacctt gatttttcaa atctaaccag tgtcaacctt
    13321 gatgagtatg tgggccttga tggggacaat ccacagtctt atcgttactt catgcaagaa
    13381 aacttgttca accaaaaacc atttaaagaa agtttcttgc ctcgtggtgt taaggacaat
    13441 gctgaagctg aagttgaacg ctacaaccaa attttggctg accatccagt tgacctccaa
    13501 atcttgggaa tcggtcgcaa tgggcatatc ggctttaatg agcctggtac tccatttgac
    13561 agtcaaacgc atctagtaga acttgaccag tctactatcg aagctaatgc acgcttcttt
    13621 gctaagattg aagacgtccc aacccaagct atttcaatgg ggattaaaaa cattttggat
    13681 gccaagtcta ttattctttt tgcttacggt gagtcgaaag cagaagccat tgccggaaca
    13741 gtatctggcc cagtgactga gaacctacct gcaagtagcc tccaaaatca ccctgatgta
    13801 accatcatcg cagatgctga agcgcttagc ttactcgaaa aataaaaaag caatgttcta
    13861 ttgaacgctt tcaactcttg tataaatgga agaaaaaaat caaaattaaa ccgcattttt
    13921 gcttgacaat tattcctttt acgtgtagaa tgaaatagat attgaacttg aagggagtga
    13981 aaaaaatgtc taaaacagta gtacgtaaga atgaatctct tgacgacgca cttcgccgtt
    14041 tcaaacgtgc ggttactaaa gctggtactc ttcaagaaac acgcaaacgt gaattctatg
    14101 aaaaaccttc tgtaaaacgt aaacgtaaat cagaagtagc tcgtaaacgt aaaaaattct
    14161 aattgaaatg aaaggctaga gaaatctagt cctttttctt ttaaataaat actccaaagc
    14221 ctgcaaaaat ctgaaacttc ctcctacaat ttgatataat agagagaaga actcatttga
    14281 aggaggaaat gatgtcggtt ttagtaaaag aagtgattga aaagcttaga ctagatattg
    14341 tctatggtga accagaattg cttgaaaagg aaatcaatat agcggatatt acgcgacctg
    14401 gtcttgaaat gacaggctat tttgactact atacaccaga gcggattcaa cttttgggga
    14461 tgaaggagtg gtcttatctg atcagcatgc cttccaacag ccgttatgaa gttttgaaaa
    14521 aaatgtttct acctgagaca ccagcagtca ttgttgcccg tggtttggtg gttccagagg
    14581 agatgttaaa ggctgctaga gaatgtaaga ttgctatttt aaccagccgt gcagctacca
    14641 gtcgtttatc tggagagtta tctagctatc tggattctcg tttggcagaa cgtaccagtg
    14701 tgcacggtgt cttgatggat atttatggga tgggcgtctt gattcaggga gatagtggaa
    14761 ttggtaagag cgagacaggt cttgagcttg tcaaacgtgg tcaccgtttg gtagccgatg
    14821 accgtgtcga tatctttgcc aaggatgaga ttactctctg gggtgaacca gctgaaattt
    14881 tgaaacactt gattgaaatt cgtggggttg gtattatcga tgttatgagt ctctacggtg
    14941 cgagtgctgt caaggattct tcacaggttc agcttgctgt ctatttggaa aattacgata
    15001 cacataagac ctttgatcgt cttggaaaca atgcagagga acttgaagtt tctggcgtag
    15061 ccattcctcg tattcgtatt ccagttaaaa caggtcgtaa tatctctgtt gtgattgagg
    15121 cagctgccat gaattatcgt gccaaggaaa tgggctttga tgcgacccgt ttgttcgacg
    15181 aacgactgac aagtctcatc gctcgaaatg aggtgcaaaa tgcttgatcc aattgctatt
    15241 caactaggac ccctagccat tcgttggtat gccttatgta ttgtgacagg cttgattctt
    15301 gcggtttatt tgaccatgaa agaagcacct agaaagaaga tcataccaga cgatatttta
    15361 gattttatct tagtagcctt tcccttggct attttaggag ctcgtctcta ctatgttatt
    15421 ttccgatttg attactatag tcagaattta ggagagattt ttgccatttg gaatggtggt
    15481 ttggccattt acggtggttt gataactggg gctcttgtgc tctatatctt tgctgaccgt
    15541 aaactcatca atacttggga ctttctagat attgcggcgc ctagcgttat gattgctcaa
    15601 agtttggggc gttggggtaa tttctttaac caagaagctt atggtgcaac agtggataat
    15661 ctggattatc tacctggctt tatccgtgac cagatgtata ttgaggggag ctaccgtcaa
    15721 ccgactttcc tttatgagtc tctatggaat ctgcttggct ttgccttgat tctgattttt
    15781 agacggaaat ggaagagtct cagacgaggt catatcacgg ccttttactt gatttggtat
    15841 ggtttcggtc gtatggtcat cgaaggtatg cgaacagata gtctcatgtt cttcggactt
    15901 cgagtgtccc aatggctgtc agttgtcctt atcggtctcg gtataatgat cgttatttat
    15961 caaaatcgaa agaaggcccc ttactatatt acagaggagg aaaactaaat gttagaagtt
    16021 gcatatattc ttgttgccct agctttgatt gtctttttgg tctatctgat cattactgta
    16081 caaaagcttg gtcgtgtcat cgatgaaaca gaaaagacga ttaaaacctt gacttcagat
    16141 gtggatgtga ccttgcatca caccaatgag ttgttggcta aggtcaatgt cttggcagat
    16201 gatatcaatg tcaaggtggc tacgattgat ccactcttca gtgctgttgc agatttatct
    16261 ctatctgttt cagacctcaa tgaccatgcg cgtgtcttga gcaagaaagc ttcatcagct
    16321 ggttcaaaaa cactcaagac tggtgcaagt ctgtcagctc ttcgtcttgc aagtaaattt
    16381 ttcaaaaaat aaaaaaggag aatccttatg ggtaaattat cctcaatcct tttaggaacc
    16441 gtttcaggtg cagctcttgc cttgttttta acaagtgata agggcaaaca agtttgcagt
    16501 caggctcaag attttctaga tgatttgaga gaagatccgg agtatgccaa ggagcaagtc
    16561 tgtgaaaaac tgacagaagt taaggagcag gctacagatt ttgttctgaa aacaaaagaa
    16621 caggttgagt caggtgaaat cactgtggac agtatacttg ctcaagctaa atcctatgct
    16681 tttcaagcga cagaagcatc aaaaaatcaa ttaaataatc tcaaggaaca atggcaagaa
    16741 aaagccgaag ctcttgatga ctcagaagag attgtgattg atataacaga agaataaacc
    16801 atcaccatct ccgaacggac tatgtatctg gggatggtga tttttatctg gaatctagtc
    16861 tttgtggtat aataattact atgcagaaaa aaccaacgtc agcctatgtg cacatcccat
    16921 tttgtaccca gatttgttat tattgtgatt tttcaaaggt cttcatcaaa aatcagccag
    16981 tcgacagcta tttagagcat ctgctggaag agtttcgttc ttatgatatt gaaaagttgt
    17041 caacccttta tatcggtggt ggaacaccga cagccctgtc ggctccgcaa ctggaggttt
    17101 tactgaatgg cttgactaaa aacttggact tgtctgtctt agaagagttg accattgaag
    17161 ccaatccagg cgatttggat gcggataaga tagctgtttt gaaaaattcg gctgtcaatc
    17221 gtgtttcgct aggtgtccag acctttgatg ataagatgtt gaaaaagatt gggcgcagtc
    17281 atttggagaa ggatatttat gaaaatatcg atcgcctgaa actggctggt tttgacaaca
    17341 tctccattga tttgatttat gctctgcctg gtcagaccat ggagcaagta aaggaaaatg
    17401 tggctaaagc cattggactg gatattcccc acatgagttt gtatagtttg attttagaaa
    17461 accatacggt ctttatgaac cggatgcgac gtgggaaatt gcctctgcct aaggaggaac
    17521 tagaagcgga gatgtttgag tacatcattg cagagctgga gcgagcgggt tttgagcatt
    17581 atgagatttc taatttctcc aaacccggct ttgaaagtcg tcataatctc atgtactggg
    17641 acaatgctga atactatggt attggtgcag gggcatctgg ttatgtcaat ggagtacgct
    17701 ataaaaatca tggtcccatt cgtcattatc tcagtgcggt tgaggaaggc aatgcttgta
    17761 ttacagaaga tcacctgagt caaaaggagc aaatggaaga agaaatgttc ttgggactcc
    17821 gcaagaaatc cggggtttcc atggcgcgat ttgaggaaaa atttggacag tcttttgctg
    17881 gactttatgg agaaattgtc agagatttgg ttcaacaagg cctcatgcag attgagggtg
    17941 accacgttcg catgacaaag agaggtctct ttttgggaga tactgtagca gaacgattta
    18001 ttttggagta ggatcatggg cttaacttat caaatgaaaa tgaaaattcc ttttgatatg
    18061 gctgatatga acggtcatat caaacttcca gatgtgattt tgctgtcact gcaagtttca
    18121 gggatgcagt cgattgaact gggagttagt gataaggcca ttttggaaga ctataatctg
    18181 gtctggatta tcgcagaata tgatattgag gtggttcgtt tgcctcgttt tgcggaagaa
    18241 attaccatcg aaacggaagc cttgagctac aatcgacttt tttgctaccg ttgctttact
    18301 atttataatg aagcggggca ggagctcatc catatgatgg cgacctttgt tctcatggac
    18361 cgcgacagtc gaaaagtcca tgctgttgaa cctgagattg tggctcctta ccagtctgat
    18421 tttgataaaa aacttatccg tggaccgaag tatgagtcct tggaagagct gatcagcaag
    18481 gattaccatg ttcgttttta cgacttggat atgaatggtc atgtcaataa cagtaaatac
    18541 ttggactgga tttttgaggt catgggagcg gattttttga cccactatat tcccaagaaa
    18601 atcaacctca agtatgtcaa ggaagttcga ccaggtgggg tgattacatc ggctgttgaa
    18661 cggactggac tggaaagcaa gcatgaaatt acaagtgatg gggttatcaa tgcccaagca
    18721 atcattactt ggcaagaaat aaaaaaggct tagggagaaa tagatgaaat ataaaggcta
    18781 tttaattgat ttagacggaa ccatttataa ggggaaagac cgaatccctg ctggagagac
    18841 ttttgttcat gaattgcaaa agcgggacat tccctatctc tttgtaacca acaatacaac
    18901 ccgcactcca gagagtgtta aggagatgtt gactcagaat tttaatatcg atacgcccct
    18961 atcgactgtc tacacagcga ctttggcaac catcgactat atgaatgatt tggggcttga
    19021 aaagaccgtc tatgtcgtcg gagaagcagg actcaaggaa gccatcaagg cggctggtta
    19081 tgtggaagac aaggaaaaac ctgcctacgt ggtagttggt ctggattggc aagtcgacta
    19141 tgaaaaattt gccacagcaa ctcttgctat tcaaaagggt gcccatttta tcggaaccaa
    19201 tcctgacctc aacatcccga cggaacgcgg tcttttgcca ggtgctggct cactgattac
    19261 gctgcttgaa gtagcgacac gagtgaagcc ggtttatatc ggaaaaccaa atgccatcat
    19321 tatggacaag gcggttgagc acttaggttt ggaacgtgaa gagttaatca tggttgggga
    19381 caattatttg actgatattc gggctgggat tgacaatggc attccaacgc tcttggtgac
    19441 gacaggtttt actaaggcag aagaagtagc tggcctgcca atcgcaccga cacatgtggt
    19501 ttctagcctt gcggagtggg attttgatga aaactaaatt gatcttttgg ggctctatgc
    19561 tctttctcct ctccctctca atccttctga ccatttatct ggcttggatt ttctatccta
    19621 tggagattca gtggctaaac ttaacaaatc gagtctatct aaaaccagaa accattcaat
    19681 acaattttca tatcttgatg aattatctga ccaatccttt tagtcaggtc ttacagatgc
    19741 ctgattttcg ttcgtcagca gctggtctgc accatttcgc agtggtcaag aatctctttc
    19801 atttggttca gctagtagct ctagtgacac tgccaagttt ctatgtcttt gtcaatagga
    19861 ttgtgaaaaa ggactttttg tctctttatc gaaaaagtct cctggctcta gtagtcttac
    19921 ctgtaatgat tggacttggg ggagttttga ttggttttga ccaattcttt actcttttcc
    19981 atcaaattct ctttgtggga gatgatacct ggctttttga tccagccaag gatcctgtta
    20041 ttatgatttt gccagagacc ttctttcttc atgccttcct cctctttttt gccctctatg
    20101 aaaacttctt tggctatctg tgtctgaaaa gtcgtaggaa gtgaaaggaa agatgttttt
    20161 aatttacata tataaaaata tatatatcgt ttaaaaccat cgttaagagt gaattaacca
    20221 aatccaattg tgtcaatcgt tcgcaaacag cctatttttc ctgaaaaaat aggctttttt
    20281 tctaaaaatc cctagtcaag cgctttattt ttttgtataa tagaagtagc aaagtataga
    20341 taagaagaga aaagcatgat tacactattt ctatcaccga gctgtacatc atgtcgtaag
    20401 gctaaggcct ggttagaaaa acataaggtt ccctttgtgg aacacaatat tatgaccagt
    20461 cctttaacaa gaaaagaatt gcaacacatc ctttccttga ccgaaaatgg tactgatgac
    20521 atcatttcaa ctcgttcaaa aatttttcaa aaattgaata ttgatgtaga gagtatttcg
    20581 gtatcggaat tgcttcattt gattgagcag tatcctagtc ttttgcgtcg tccaattatt
    20641 attgatgcca agcgtatgca aatcggtttt aatgaagatg agattcgtgc ttttctccct
    20701 cgtagttatc gtaagcaaga actaaaagaa gcaagaatga gagctggtat tagttaatga
    20761 acaaacagta tagttaccca ctagatttgt cgtggagcac tgaagaactt gcttcagtgc
    20821 tttctttttt taatgatgtt gaagctgcct atgaaggcaa agtagaggct aaaaagttac
    20881 tggactccta taagggattc aaagcggtcg tgccaagcaa gagcgaagag aaacgtttgg
    20941 gacgagaatt tgaaacggtt agtggctatt cactttaccg agcagttcag gctgccaaag
    21001 aaaaagggga aggaaagatt tctcttggaa agtaaatttg aatttgctaa agagcttgtt
    21061 aagaaagcag gtcagtacat tcttgaccat atgcaggaag acttgcgtgt tgaaaccaag
    21121 tcctctccaa cagatttggt gaccagactg gacaaagaag ttcaggaact cttggttggt
    21181 gagattttgt cccgttatcc tgaggataag atttgtgctg aagaaggttg tctgcgagcc
    21241 tcggttcaag agggcaaggt ttgggtcatt gatcccattg atggtaccaa taattttgta
    21301 gcccagcagg aagattttgc tgttatgatg gcttattttg aaaatggtca gggacagttt
    21361 ggtctgattt atgatgtggt caaaggggat tgttaccatg gtggtgggga atttccggtt
    21421 tgccgaaacg ataagcccct agctcccttt caagcaaaac cacttggaga ttttctcatt
    21481 gcgggaaata gtggcatgct ggaaaccaac gaatgggggc tggctgattt gagtcgagcg
    21541 gtcctcggtg tacgtgtcta tgggagtgcg gctattagtt ttgccaagat tttgtcaggg
    21601 catttattga cctatgtcac ctatctgcaa ccatgggatt atgctgcggc tagtatttta
    21661 ggggaaagtc tgggctatcg ggttgtgact ctatctggtg aggctcctga ttttcaaacc
    21721 agacaaccgg tcatgatgct acctcttgag atgcaggagg aaattcagtc ctatatttac
    21781 gaaaggaaaa gaacttaaat gcaatttcca gaaggatttg ttgaaaaata tgaagagata
    21841 ctaggagatg aggcaagaga ttttcttgcc tcttttgagg aggaagcggt ttcggccttt
    21901 cgggtcaatc ccttaaaaga agagcaactt tccttttctg atgccattac tcaaacccct
    21961 tggggccact atgggaaggt ttcagggaaa tcgcctgagc atgctacagg tttagtttat
    22021 tcgcaagaac ctgctgctca aatggtggct caagtagccc aacccagtcc tggtatgaag
    22081 gtcttggact tggctgctgc accagggggc aaatcaactc aactggcagc ctatctagca
    22141 ggggaggggc tacttgtttc caatgaaatt tcaagcaaac gggctaagat tttggttgaa
    22201 aacatggagc gttttggagc gacaaatgtc gtggtgacca atgaatctgc cgaccgcttg
    22261 gtcaaggtct ttaaaggcta ttttgactta atcgttcttg atgccccttg ctctggtgaa
    22321 ggaatgtttc gtaagcaacc tgatgctatg gactattgga gcttagatta tccgagtcaa
    22381 tgtgctagct tgcaaagaga aattctggag gatgcagtga ccatgttagc tgaaggtggt
    22441 catctggttt attcgacctg tacctgggca cccgaggaaa acgaagagat tgtcaattgg
    22501 ttgctggaag agtatgattt tgacttgttg ccagtagagc atatcaatgg aatggtagct
    22561 ggtattgacc tgccagaaac ggctcggatg tatcctcatc agtttaaggg agagggtcag
    22621 tttgttgcct atctacagtt taagggtaac aatccagctc ctaaatttaa ggcaagtaag
    22681 agtaacctca gccgtgaaca agttgccttg tggcaggaat ttgcccaaaa ccatttgaag
    22741 gtcaatctac cgggtatctt gcagactttt ggagaccagc tttatctctt gccagaactt
    22801 ttgccagatt tagggaagct caagattgct cgcaatggac tgcatctggg tacttttaag
    22861 aagaaacgct ttgagcccag tttcgctctt ggtttagcct tgaaaccgag tcaggtcgaa
    22921 cagtcggttg aaattggcca agaagagttt gtcaagtatg cggctggaga aaccgttcag
    22981 ctggcagaaa gtctgccaaa tggttggtac caagttttgg ttaaaggcaa tggcttgggc
    23041 tttgcaaagg ttactggaaa tgttttgaaa aattattttc caaaaggcct cagattcaaa
    23101 tgaaaatgct agtcaaatat cttattctat gttatagtga aagtatggat ttttttagta
    23161 ggatgattct tgatatcttg attgccatca catgtagttt tactactcga tgaaaatcaa
    23221 agaacaaact aggaagctag ccatagatag ctcaaaacac tggtttgaag agattttcaa
    23281 agagtacaag aagtttagtt attagcgttc ttaccgcttg taaactagat ttctcataaa
    23341 atagaatctt ttccttttag ttgtaaacta gtctgggaga gtagagaggt ttgagatacc
    23401 tttctagctt ttggattatc atctaaggag agtaatttcc cttgcattaa aaaggggaaa
    23461 aagagacacg aaatgactat aatgggtgac aatgggggaa gggatagaca agagatttta
    23521 tccacatatg aaaaaaggag gttaggaaag agtaatatag cctatattat ataaataatc
    23581 aattgcgcag aaatttggta agaattcatg cgtcaactca taaagaacta cttaaaaaat
    23641 tcacagtatt cataattatt ttcgaggaga aaaacagtga aaaaaagaaa aaagcttgct
    23701 ctgtctctta tcgctttttg gctgacggct tgtttagtag gctgtgctag ctggattgat
    23761 cgtggagaat ccataacggc tgttggctca actgccttgc aacccttggt tgaagtagcg
    23821 gcagatgaat ttggcacgat ccatgttgga aaaacggtca atgtccaagg gggaggttct
    23881 ggtacaggct tgtcccaggt tcagtctggg gcagttgata taggaaactc agatgtattt
    23941 gctgaggaaa aagacggaat tgatgcttct gctcttgttg accacaaggt cgcggtagct
    24001 ggcttggctc tgattgtcaa taaggaggtt gatgttgata acctaacgac agagcaactt
    24061 cgtcaaatct tcataggtga ggtaaccaat tggaaagagg ttggtggtaa ggacttaccc
    24121 atctctgtta tcaatcgggc agccggctct ggttctcgtg ctacctttga tactgtcatt
    24181 atggaaggtc agtctgccat gcaaagtcag gagcaggatt caaatggagc ggtaaaatca
    24241 atcgtatcaa aaagtccagg agctatctct tatttatctc ttacctatat agatgattcg
    24301 gtcaaaagca tgaagttgaa tggctatgac ttaagtccag aaaatataag tagcaataat
    24361 tggcccttgt ggtcttatga gcatatgtat acattggggc agcccaatga gttggctgca
    24421 gaatttctca attttgttct ctcggatgag acccaagaag ggattgtcaa aggattgaag
    24481 tatattccga ttaaggaaat gaaggttgaa aaagatgctg ccggaactgt gacagtgttg
    24541 gaagggagac aataatgaat caagaagaat tagctaagaa aatgttgctt ccatcaaaga
    24601 attctcgtct ggagaaatta ggaaaaggtt tgacctttgc ctgtctttct ttgatagtca
    24661 tccttgtggc catgattttg gttttcgtag cgcaaaaagg cttgtcgacc ttctttgtca
    24721 atggtgtgaa tatctttgac tttcttttgg gaggaatttg gaatccttct agtaaagaat
    24781 ttggtgccct tcctatgatt ttgggttcct ttatcgttac cattctctca gcccttatcg
    24841 caaccccctt tgctattggt gcagcagttt ttatgaccga agtatcacca aaaggggcga
    24901 agattttgca accagctatt gaactcctgg ttgggattcc ttcagtagtg tacggattta
    24961 ttggcttgca agtcgtcgtt ccctttgttc gcagtgtctt tggtgggact ggttttggga
    25021 ttttgtcagg gatttccgtc ctctttgtca tgattttgcc gaccgtaacc tttatgacaa
    25081 cggatagctt gcgtgcggtt cctcgttatt atcgtgaagc cagtttcgct atgggagcca
    25141 ctcgctggca gactatctgg cgtgtgatct tgaaggcggc ccgttctggt attttcactg
    25201 cagtggtctt tgggatggcg cgtgcctttg gtgaggcttt agctatccag atggttgtcg
    25261 gaaactcagc tgttatccca acttccttga ccacaccagc tgcaacttta acttctatat
    25321 taactatggg aattgggaac actgtcatgg gaactgtaaa taataatgtt ctctggtcac
    25381 tggccttggt actgctcttg atgagtttag tttttaacag tgtgattaaa ttgattacga
    25441 aagaaagagg aaagaaaaat tatgcgcgct aagaaattag ataaacttgc aacagctgtc
    25501 ctctatacga ttgctagcat cattgtgaca atcttggctt ccttgattct ctatatcttg
    25561 gttcggggct tgccccatat ctcttggtct ttcttgactg gaaggtcttc tgcttttcaa
    25621 gcaggtggtg ggattggcat tcagctttac aattcctttt tcctattggt cattaccttg
    25681 attatttctg tacctctttc tatgggagct gggatttact tggctgaata tgctaaaaaa
    25741 ggtcctgtta ccaactttgt gcggacttgt attgaaatct tgtcctcttt accatcagtg
    25801 gtggtgggtc tctttggtta cttgatcttt gtagttcagt ttgagtatgg attttcaatc
    25861 atttcaggtg ccttggcctt gacagtcttt aacttgcctc agatgacgcg taatgtagag
    25921 gatagtttga aacacgttca ccatacccaa cgtgaggctg gtctggctct tgggatttct
    25981 cgctgggaga cagtggttca tgttgttatt ccagaagcgc ttccaggtat tgtaacgggt
    26041 gtcgtcttgg catctggtcg tatctttggc gaagctgcag ctctgatcta tacagcaggg
    26101 caatcggcgc cagctcttga ctggtctaac tggaatatcc tcagtgtgac tagccccatc
    26161 tctatcttcc gtcaagcaga aaccttggct gtccatatct ggaaagtcaa tagtgaaggc
    26221 actattccag atggaaccat tgtatcagca ggttctgccg ctgtgctcct gatctttatc
    26281 ctgattttta actttggagc tcgtaagttc ggaagctatc tacacaagaa attaaccgct
    26341 gcctaaagga gaagccatgt caacatataa ctgggatgag aagcatatcc ttacctttcc
    26401 tgaagaaaaa gtagcccttt ctactaagga tgtccatgtt tactatggta aaaatgaatc
    26461 cattaagggg attgatatgc aatttgaaag aaataaaatt acagctttga ttggtccgtc
    26521 gggatcgggg aaatctacct acttacgcag tctcaatcgc atgaatgata ccattgatat
    26581 tgctaaagta actgggcaga ttctctatcg tggaattgat gtcaaccgtc cagaaatcaa
    26641 cgtttatgaa atgcgtaaac acattggaat ggtttttcaa cgccccaatc catttgctaa
    26701 gtcaatttac cgtaatatta cctttgcgca tgaacgtgct ggagttaagg ataagcaagt
    26761 cctagatgaa atcgtagaaa cctcccttcg tcaggctgcc ctctgggatc aggttaaaga
    26821 cgatctccac aagtcagcct tgaccttatc aggtggtcag caacaacgtc tctgtatcgc
    26881 tcgtgccatc tctgttaagc cagatatcct cttaatggat gagccagcct cagccttgga
    26941 tccgattgcg accatgcaac tagaagagac catgtttgag ctcaagaaaa actttaccat
    27001 catcattgta acgcataata tgcagcaggc tgctcgtgca agtgactata caggcttctt
    27061 ttacttgggt gatttgattg agtatgacaa gactgcaact attttccaaa atgccaagct
    27121 acagtccacc aatgactatg tatctggtca ctttggttag aaaggaaacc gtatgacaga
    27181 tgcgatttta caggtatcag acctgtccgt ttattataat aaaaagaagg ctttgaatag
    27241 tgtttcccta tctttccaac ctaaggaaat tacagccttg attggtccat ctggatcagg
    27301 gaagtcaacc ctcctcaagt ctctcaaccg catgggagat ctcaatccag aggtgaccac
    27361 aactggatcc gtggtgtaca atggtcacaa catctacagt ccgcgtacag atacggttga
    27421 attacgtaag gaaatcggaa tggttttcca acaacctaat cctttcccta tgactatcta
    27481 tgagaatgtt gtctacgggc ttcgtatcaa tggaattaag gataagcagg ttctggatga
    27541 agccgtagaa aaagccttgc aaggtgcctc tatctgggat gaggtcaagg atcgtctata
    27601 tgattcagct attggattgt caggtggtca acagcagcgt gtctgcgtgg cccgtgtctt
    27661 ggcaactagt cctaaaatca tcctcttgga tgagccaact tcggctttgg atccgatttc
    27721 agctggtaaa attgaggaaa ccttgtatgg tctaaaagac aagtacacca tgcttctggt
    27781 aacccgttcc atgcagcaag cttcacgtat ctctgataag acaggatttt tcctagatgg
    27841 agatttgatt gaatttaatg ataccaagca gatgttcctt gatccccaac acaaggaaac
    27901 ggaagactat attacaggaa aatttggata aggagatgaa agatgttacg atctcaattt
    27961 gaagaagatt tagagaaatt acataaccag ttctacgcta tgggacaaga agtgctctca
    28021 caaatcaatc gtacggtacg tgcttttgtc acgcatgacc gtgacctggc aaaagaggtc
    28081 atcgaagatg atgcagaagt aaatgaatac gaagtgaaac tggaaaagaa atcatttgaa
    28141 atgatcgcac tccaacaacc agtctctcaa gatttgcgta cagtcttgac tgtccttaag
    28201 gctgtatcag atgtggagcg tatgggggat cacgctgtag ccattgccca ggcaaccatc
    28261 cgtatgaagg gggaagaacg catcccagct gtagaggaag aaattaaaaa aatgggacgt
    28321 gaagttaaaa gcgttgtgga agcagcactt gatctttatc ttaatggttc tgttgacgac
    28381 gcataccggg tggcctccat ggatgagcaa attaaccact attttgaaac tatccgtgac
    28441 cttgcgactg aagagattaa gaaaaatcca gaagccattg ttacgggtcg tgattatttc
    28501 caagttattt cctacttgga gcgtatcggt gactatgcta aaaatatctg tgaatgggtt
    28561 gtctactttg aaacaggtaa gattgtcgaa ctataaaata gtttaattct gtataaaaag
    28621 gagcttgaaa tcaactgatg gctccttttt ttgaacgaaa aaatattttt gagataaaaa
    28681 tttaaaaaac acttgacaag taacttggat atcgttataa ttatacaaaa ttaacagaga
    28741 ggttgtttat ttatgaaatc aaaaaaatgg atatttgttt tatgtaattt tcttgcaagt
    28801 ttcttcttag tagcttgcca gtcaggttct aatggttctc agtcagctgt tgaggccatt
    28861 aagcaaaagg ggaaattagt tgtggcaacc agtcctgact atgcaccctt tgaatttcaa
    28921 tcattggttg atggaaagaa ccaggtagtc ggtgcagaca tcgacatggc tcaggctatc
    28981 gctgatgaac ttggggttaa gttggaaatc tcaagcatga gttttgacaa tgttttgacc
    29041 agtcttcaaa ctggtaaggc tgacctagca gttgcaggaa ttagtgctac tgacgagaga
    29101 aaagaagtct ttgatttttc aatcccatac tatgaaaaca agattagttt cttggttcgt
    29161 aaggctgatg tggaaaaata caaggattta actagcctag aaagtgctaa tattgcagcc
    29221 caaaaaggga ctgttccaga atcaatggtc aaggaacaat tgccaaaagc tcaattaact
    29281 tccctaacta atatgggtga agcagtcaat gaattgcagg ctggaaaagt agatgctgtt
    29341 catatggatg agcctgttgc acttagttat gctgctaaaa acgctggctt agctgtcgca
    29401 actgtcagct tgaagatgaa ggacggcgac gccaatgccg ttgctcttag aaaaaatagt
    29461 gatgatttga aagaagtggt agacaaggtc atccaaaaac ttaaggatga aggaatttac
    29521 caaagctatc ttgaaaaagc agcaagtcta actgaagttg aagaataaga aaaagcagag
    29581 ttggatgtca ttccaattct gcttttaaat agtttaaaac attttccaga ttgtctaggg
    29641 acaccttggc aaattgataa ggacaggtac ttaaataggc ctcttcaaag aagtccaagc
    29701 ccggttgact gtgtttgaga ctggcgattt taggatactg tctcaggtct agcaataaac
    29761 catcgtgtag gggataatga ggaaggggac aaggtgtttt agttatcctt tcctcgattt
    29821 gtttttggta agattcatga ttggtcaagc gagccaaacg atttttttca aacaattgac
    29881 tgtcaatata gagtgacagg gccttttgca taatgaggtt gctgtcgtag tctaggatat
    29941 ttttgtaggc cacaaatgct tctttgatag catttggaag aatgagtgct gtaatacgaa
    30001 gggcaggaaa aaggctggtc gagaaggact tgatataaat gacatgctcc tctgtatcaa
    30061 gatagtggaa ggtttggccc ttcttggagt ccaaatcacc cagataatcg tcctctacga
    30121 tatagacatc atacttggca gctaagttaa gaatagatcg tttgtcttgc tcagaatagg
    30181 aatgtcccag aggatagtga aatctaggaa tggtgtagaa aaatttaatt tttcctgttt
    30241 tgaagtggcc ttccagctcc tccaagtcaa tcccatcaat gcctcgttca atcgtttgat
    30301 agtccagccc ctgtgcaatc aagaggcgat tcatccgatg gtaggttggc tgttccacca
    30361 agatttcctt ggcttgtcta ggaaaggata tttgagagag gataaataag gcttgttggg
    30421 ttccagaagt cagtactagt tggttagcct tgcagtagag agcttgctca aagaggagtt
    30481 tgtgaatgga ctgtcttagg tcttctaatc cttcttgatt gtcatagtag ttgaagaggt
    30541 agttttctcg gccaatcaag gtttcattga cacagagtcg gaaatcgtca taggcactgg
    30601 catgttcgtc ggtaacctcg atttctaggt cttgatgttg cccttgttct aatacatagt
    30661 agccactctg aggcttggca tagaggtatt gttcgtgccg taattccagc agggctcgtt
    30721 gaatggtgtc cttgctgcag tgaaagtcaa ggctcagttg acggatagaa ggcaggcgac
    30781 tacccgtcgg aaatcgtcca gactcgatac catttttcag ataggaaacg acctctttgt
    30841 acttgctttg tttcttcatt ccagacctcc cttgattttg ttacattgta cctttttttt
    30901 tccttcttgg caatgtctag agcgtttctc tcgttcacat ctaggggcaa atgtggtata
    30961 cttaggagta agatttatag aataacagac aagaaagtga atggataaga acgtgcagga
    31021 accagtgaaa ttatttcaat acaataccct tggagccttg atggctggcc tttatggtgg
    31081 tactatgaca gtaggagaat tgctagaaca tggtgacctt ggtttgggaa ccttggattc
    31141 cattgatggg gaattgattg tcttggatgg caaggcttat caggccaaag ggtcaggaga
    31201 ccagccagaa attggggaag tgtcaccaga tgcccttatt ccttacgctg cagtggtacc
    31261 gcatcaggca gaggtcattt tccgccagcg ctttgagatg acagacaagg aattgaaaga
    31321 acgaattgag tcttattatg atggggaaaa tcttttccgc tctatcaaga ttcgggggga
    31381 attttcacat atgcatgtgc gtatgattcc taagtcaaca cccgatacca agtttgctga
    31441 tgtcgcaacc catcaaccgg aatatagtcg tgacaatgtt gcggggacta ttgttggttt
    31501 ctggacgcct gagattttcc atggggtcag tgtggcaggc taccatctgc acttcatatc
    31561 agatgatttg accttcggtg gacatgtcat ggattttgtc atcaaggaag gcattatcga
    31621 ggtgggagca gttgaccagt tggaccaacg tttcccagtc caagaccgtc aatacttgtt
    31681 tgctaagttc aatgttgacg agatgaaaaa agatattgaa aaggcagaat aggagaagaa
    31741 aatgaccatt catatcatta ttaccatgtt gctgttgcta gcttttctga taggaagcat
    31801 ttggtttgcc aaaaagaaat accagattaa tctagctgtc ttgggcttgg gtgcagtcgc
    31861 tttctttgtc tcttcgcaga ttttggaaaa actggtgcat atcttgattt tgcatcctca
    31921 aaaagacggt agtattgccc tcttgcaaga tcatccgctt atctatatta tctatggcct
    31981 agccatggca gcattttttg aggaaacggc tcgtcttgtt ttcttcaaat ggttggagaa
    32041 aaagagaagt ttggaaaagg cagatgcctt ggcctatggc ctagggcatg gtggcttgga
    32101 gttgattttt ctaggcctta ttagtttact caatctttac atcgttcttt cggcagttca
    32161 aactcagaat ccacaggtta tgcaattact gtctgaaaat atgttaaaaa ccattcagtc
    32221 actttcggtc tggcagattt atttgcttgg ttttgagcga atcttggcgc ttggtttcca
    32281 attacttttg acagtttggg tttaccaagc tgttcgccag aagaaatgga tttatctcct
    32341 agcagcctat ggcttgcatg ccttctttga tctggcacca tctcttttcc aagtaggctg
    32401 gttgacaaat ccagtcttgg ttgaagtgat tctagcactg gagctcgttc tggttgccta
    32461 tggaaccaag gaaatctttt gtaaaaaatc ataaaaaggg gggaacctct ttttcttatg
    32521 caaaatccaa acaaggtatt tttatggtcg tcaaatgtct ctaaaaatgg tataatggaa
    32581 tgaattttgt aaaaggaaga gtgacatgtc tgtaagagaa aaaatgcttg aaatcttaga
    32641 aggaattgat atccgtttta aggaaccctt gcatagctat agttatacaa aagtaggtgg
    32701 agaggctgat tatttggtct ttccacgaaa tcgttttgag ttggctcgcg ttgtgaaatt
    32761 tgccaaccaa gaaaatatcc cttggatggt tcttggcaat gcaagcaata tcatcgttcg
    32821 tgatggtggg attcgtggat ttgtcatctt gtgtgacaag ctcaataacg tttctgttga
    32881 tggctatacc attgaagcag aagctggggc taacttgatt gaaacaactc gcattgccct
    32941 ccgtcatagt ttgactggct ttgagtttgc ttgtggtatt ccaggaagcg ttggcggtgc
    33001 tgtctttatg aatgcgggtg cctatggtgg cgagattgct cacatcttgc agtcttgtaa
    33061 ggtcttgacc aaggatggag aaatcgaaac cctgtctgct aaagacttgg cttttggtta
    33121 ccgccattca gctattcagg agtctggtgc agttgtcttg tcagttaaat ttgccctagc
    33181 cccaggaacc catcaggtta tcaagcagga aatggaccgc ttgacgcacc tacgtgaact
    33241 caagcaacct ttggaatacc catcttgtgg ctcggtcttt aagcgtccag tcgggcattt
    33301 tgcaggtcag ttaatttcag aagctggctt gaaaggctat cgtatcggtg gcgtagaagt
    33361 gtcagaaaag catgcaggat ttatgatcaa tgtcgcagat ggaacggcca aagactacga
    33421 ggacttgatc caatcggtta tcgaaaaagt caaggaacac tcaggtatta cgcttgaaag
    33481 agaagtccgg atcttgggtg aaagcaagta ggaagctgta tttgaaaagc tgctgctatg
    33541 tcatggaaag gggggtgaaa gcctattggt agcgaagatg tatgcaggtg gttttactcc
    33601 ctgcaagagg tagtggcgac ctgacagagc cccgatcggt taatctatga aaaagaagga
    33661 atttatgcca attgaaaaaa tcaattatcg aattcaaaaa cgtctctaaa gtttttgaag
    33721 acagcaacac caaggttctc aaagacatca actttgagtt ggaagaaggg aaattctaca
    33781 cccttctagg tgcatctggt tcggggaaat caactatcct aaacattatt gcaggtttac
    33841 tggatgcgac gacaggagat atcatgctag acggtgttcg tatcaatgat attccaacca
    33901 acaagcgcga cgtacatact gtcttccaat cctatgcctt gttcccacat atgaatgtgt
    33961 ttgaaaatgt tgcctttcca cttcgcttgc gtaacattga taagaaagaa atcgagcaac
    34021 gtgtagcgga agttctcaag atggttcagt tggaaggtta tgaaaaacgt tccatccgca
    34081 aactttctgg aggacaacgt cagcgtgtgg ctatcgcccg tgctatcatc aaccaacccc
    34141 gtgtggtttt gttggatgag cccttgtcag cgctggactt gaaattaaga acagacatgc
    34201 agtacgaact gcgtgaactg caacaacgat tgggcattac ctttgtcttt gtcactcacg
    34261 atcaggaaga agctcttgcc atgagtgact ggattttcgt tatgaatgat ggcgagattg
    34321 tccagtctgg aacccctgtg gacatctacg atgagccaat caaccacttt gttgccacct
    34381 ttatcgggga gtcaaacatc ttgccaggta ccatgattga ggactacttg gtcgaattta
    34441 acggcaaacg ctttgaagcg gttgatggtg ggatgaagcc aaatgaacct gttgaggtcg
    34501 ttattcgtcc agaggacttg cgcattaccc ttcctgaaga aggcaagctt caagttaagg
    34561 tcgataccca gctcttccgt ggggtgcatt atgaaattat cgcctatgac gaacttggaa
    34621 atgaatggat gatccactca acccgtaagg ccatcgtggg tgaggaaatc ggtctggact
    34681 ttgaaccaga agacatccac atcatgcgtc tcaatgaaac cgaagaagag ttcgatgctc
    34741 gtattgagga gtacgtagaa atcgaagagc aagaagcagg tttgatcaat gcaatcgagg
    34801 aggaaagaga tgaagaaaac aagctctaaa ctctttgtag taccctacat gctttggatt
    34861 gccctctttg tattggcacc cttggtcttg attttcggtc aatccttttt caacatcgaa
    34921 ggccagttca gtttagaaaa ttacaaatct tactttgcgt cacaaaactt gacctatctt
    34981 aaaatgagtt tcaactcagt gctttatgca ggcattgtga cctttgtgac actgcttatc
    35041 agttatccga cggccctctt tttgacccgt ctcaaacacc gtcaactctg gattatgctg
    35101 attattctgc caacttggat caaccttctt cttaaggctt atgcctttat cgggattttt
    35161 ggtcagaatg gctctattaa ccaattcttg gaatttatcg gaattggttc acagcagttg
    35221 ctatttactg atttctcatt tatctttgtc gcaagctaca tcgagctccc ctttatgatt
    35281 ttgccgattt tcaatgtctt agacgatatg gataataatc tcatcaatgc tagttacgac
    35341 cttggtgcaa ctaagtggga gaccttccgt catgtcatct tccctctatc tatgaacggt
    35401 gtgcgaagtg gggttcagtc ggtctttatc ccaagtttga gtctcttcat gctgacccgt
    35461 ttgattggtg ggaaccgcgt tatcaccttg gggacggcta ttgagcagaa ttttctaacc
    35521 aatgacaact atggtatggg ttcaactatc ggtgtgattc tcatcctgac catgttcatc
    35581 accatgtggg tgactaagga aaggagagaa cgatgaaaaa atttgccaac ctttatctgg
    35641 gactggtctt tctggtcctc tacctgccta tcttttactt gattggctat gcctttaatg
    35701 ctggtgatga tatgaatagc tttacaggtt ttagctggac tcactttgaa accatgtttg
    35761 gagatgggag actcatgctg attttggctc agacattttt cttggccttc ctatcagcct
    35821 tgatagcgac cattatcggg acttttggtg ccatttacat ctaccagtct cgtaagaaat
    35881 accaagaagc ctttctatca ctcaataata tcctcatggt tgcgcctgac gttatgattg
    35941 gtgctagctt cttgattctc tttacccaac tcaagttttc acttggcttt ttgaccgttc
    36001 tatctagtca cgtggccttc tccattccta tcgtggtctt gatggtcttg cctcgactca
    36061 aggaaatgaa tggcgacatg attcatgcgg cctatgactt gggagctagt caatttcaga
    36121 tgttcaagga aatcatgctt ccttacctga ctccgtctat cattactggt tatttcatgg
    36181 ccttcaccta ttcgttagat gactttgccg tgaccttctt tgtaacagga aatggctttt
    36241 caaccctatc agtcgagatt tactctcgtg ctcgcaaggg gatttcctta gaaatcaatg
    36301 ccctgtctgc tctagtcttt ctctttagta ttatcctagt tgtaggttat tactttatct
    36361 ctcgtgagaa ggaggagcaa gcatgaaaaa aatctattca tttttagcag gaattgcagc
    36421 gattatcctt gtcttgtggg gaattgcgac tcatttagat agtaaaatca atagtcgaga
    36481 tagtcaaaaa ttggttatct ataactgggg agactatatc gatcctgaac tcttgactca
    36541 gtttacagaa gaaacaggaa ttcaagttca gtacgagact tttgactcca acgaagccat
    36601 gtacactaag ataaagcagg gtggaacgac ctacgatatt gccattccaa gtgaatacat
    36661 gattaacaag atgaaggacg aagacctctt ggttccgctt gattattcaa aaattgaagg
    36721 aatcgaaaat atcggaccag agtttctcaa ccagtccttt gacccaggta ataaattctc
    36781 catcccttac ttctggggaa ccttaggaat tgtctacaac gaaaccatgg tagatgaagc
    36841 gcctgagcat tgggatgacc tttggaagcc ggagtataag aattctatca tgctttttga
    36901 tggggcgcgt gaggtgctgg gactaggact caattccctc ggctacagcc tcaactccaa
    36961 ggatccgcag cagttggaag agacagtgga taagctctac aaactgactc caaatatcaa
    37021 ggctatcgtt gcggacgaga tgaagggcta catgattcag aataatgttg caatcggcgt
    37081 gaccttctct ggtgaagcca gccaaatgtt agaaaaaaat gaaaatctac gttatgtggt
    37141 accgacagag gccagcaatc tttggtttga caatatggtc attcccaaaa cagttaaaaa
    37201 ccaagactca gcctatgcct ttatcaactt tatgttgaaa cctgaaaacg ctctccaaaa
    37261 tgcggagtat gtcggctatt caacaccaaa cctaccagcg aaggaattgc tcccagagga
    37321 aacaaaggaa gataaggcct tctatccaga tgttgaaacc atgaaacacc tagaagttta
    37381 tgagaaattt gaccataaat ggacagggaa atatagcgac ctcttcctac agtttaaaat
    37441 gtatcggaag taggagataa acgtaagaag acgaatcagt caagctggtt cgtttttaag
    37501 gaatagaagt cagtttttag aaccctatct ttttctattc tagttgctta tttgcttgcc
    37561 tagtagtata ctaagcctat attcttcaaa ccacgtcagc gttgccttgc cgtactcaag
    37621 tacagcttga ggctagcttc ctagtttgct ttttgatttt tattgagtat taaccttaca
    37681 gaaagcggca acaaataatg aaaatgtcta cttttttcaa aaaaagtttc tggccaacct
    37741 ttatgattgt taaccaaact gttatactat cccatttaaa ggatggcttg gatcgacaat
    37801 acctaacaac tgagtccata tattgggtga taggcacctt tatatttgga aatattctag
    37861 tagctgtgtt tagtaatatg aaaatttggg ataaaaagaa aaacggcagt aagaaaaaat
    37921 atatcctgaa aaagtaatca gagatgtagg gaattggtct aattcaacgg agatcatttc
    37981 cagttgacgc aagcttaaaa aaacgttata ataagaaagt tgagaattga ttttcacttg
    38041 tcttagtcca gagaaatggc ggtgctgcga gccatctaag ctaggaagtc atgctactca
    38101 atcatacaat tgcataagaa caagagaatg acaagttcat tgaatgaagg tggtaccgcg
    38161 gtttttcgcc cttcgtgata tgagcttgtc ttttgatttt tggaggtgtt gatgaaaaca
    38221 tttcttgtca aacaaaagtt tcgtcttgga ggcgaacgct tcgctatcaa ggatgacagg
    38281 ggagaaattg cctatcaggt ggagggatca ttttttaaga ttcctaaaac ctttaccatc
    38341 tatgatgcgg ctggtgaaca agtcagtgag attagtaaag aaatcttgac cttgcttcct
    38401 cgttttgaga ttcagcttcg ggatggctcg agttttgtca ttcgtaagaa gttgaccttc
    38461 tggcgagata agtatgagtt tgataatcta ggtcttcgta tcgagggcaa tatctgggat
    38521 ttgaatttca aattgctgga tgatcgcgat cagttgattg cggaaattaa gaaggaactc
    38581 ttccatctga cctctaccta taccgtaacg gttcttgaag acgcttatgc agacctagtc
    38641 atttccctct gtgtcgcgat tgactatgtg gaaatgctgg aaagccaatc acattaaaca
    38701 agtaaataag gagacaatat gaaacaacta tctagtgcac aagtacgcca aatgtggctt
    38761 gatttctggg cgaccaaagg tcactcagta gaaccatcag taagtttggt tcctgtaaat
    38821 gacccaactc ttttgtggat caactctggg gtagcaaccc tcaagaaata ctttgacggg
    38881 accattatcc ctgaaaatcc acgtattacc aatgcccaaa aggctatccg taccaacgac
    38941 atcgaaaacg tagggaagac tgcgcgtcac cataccatgt ttgaaatgtt ggggaacttc
    39001 tctatcgggg attacttccg tgatgaagcc atcacttggg cttatgagct tttgacaagc
    39061 cctgaatggt ttgacttccc agctgagaaa ctttacatga cttactatcc agatgataaa
    39121 gattcttaca accgctggat tgaagtggga gtggatccaa gtcacttgat tccaattgag
    39181 gacaacttct gggaaattgg tgcgggacct tctggaccag atacagagat tttctttgac
    39241 cgtggggaag cctttgaccc agaaaatatc ggtcttcgcc tgcttgcaga agatattgaa
    39301 aacgaccgtt acatcgaaat ctggaacatc gttttgtcac aatttaacgc agaccctgct
    39361 gttcctcgta gcgaatacaa ggaattacca cataagaaca ttgatacggg cgctggtttg
    39421 gagcgtttgg tggccgttat ccaaggggct aagaccaact ttgaaacgga cctcttcatg
    39481 ccgattatcc gtgaagtcga gaaattgtct ggtaaggttt atgaccaaga tggcgacaac
    39541 atgagcttca aggttatcgc agaccacatt cgttctcttt catttgctat cggtgatggt
    39601 gcccttccag gaaatgaagg tcgtggttat gttcttcgtc gtcttctccg tcgtgcttct
    39661 atgcatggtc aaaaattggg tatcaacgag cctttccttt acaaactcgt tccaactgtt
    39721 ggaaaaatca tggaaagcta ctacccagaa gtgcttgaga aacgtgactt tattgagaaa
    39781 atcgttaaga gcgaagaaga atcatttgcc cgtacccttc actcaggtca acactttgcc
    39841 caaggcattg tggcagactt gaaagaaaaa ggtcaatctg tcattgctgg tcaagatgtc
    39901 tttaaactct atgatacata cggattccca gttgaattga ctgaagaaat tgctgaagag
    39961 gctggtatga ctgtagaccg tgaaggtttt gaagcagcca tgaaagaaca acaagaacgc
    40021 gcgcgtgcgt cagctgtcaa gggtggctca atgggtatgc aaaatgaaac tcttcaaaac
    40081 atcactgtag aaagtgtctt caaccacaat gctagccaat tgtcttctaa attggtggct
    40141 atcgttgctg acaatgcaga agtagaagct gtatcagaag gaactacctc acttatcttt
    40201 gcggaaacgc cattctatgc tgaaatgggt ggacaggtcg ctgaccacgg acaaatcttg
    40261 gatgagtcag gtaaggttgt ggctactgtg accaatgttc agaaagcccc aaatggtcaa
    40321 gcccttcata cagttgaagt ccttgcaccg cttgccttga accaagaata taccttggca
    40381 attgatagca atcgccgtca ccgtgtcatg aaaaaccaca ctgcgactca tttgcttcac
    40441 gctgcccttc acaatatcct tggaaaccac gcaacacagg caggatctct taacgaagtt
    40501 gaattccttc gctttgactt tacccacttc caagctgtaa ctgctgaaga attgcgtgcg
    40561 attgaacagc aagtcaacga aaaaatctgg gaagctcttg aagttaagac agttgaaacg
    40621 gatattgaca ctgctaaaga aatgggagcg atggccctct ttggtgagaa atacggcaag
    40681 gaagttcgtg tcgtgactat tggtgactac tctattgaac tttgtggtgg tactcatgtt
    40741 ggcaacactt ctgagattgg tctcttcaaa attgtcaaag aagaaggaat cggttcagga
    40801 actcgccgta tcttggcagt gactggtaag gaagcctttg aagcctatcg tgaacaagag
    40861 gatgctctta aagctgtcgc agcaaccttg aaagcacctc aagtcaagga agtacctcac
    40921 aaggtagaag gacttcaaga acaacttcgt caacttcaaa aagaaaatgc tgagttgaaa
    40981 gaaaaagccg cagctgcagc cgcaggcgat atcttcaaag atgttaagga agtcaacggt
    41041 catcgttaca ttgctagtca agtgtctgta tccgatgcag gtgcccttcg tacctttgca
    41101 gataactgga aacaaaaaga ctactctgat cttcttgtcc tagttgccgc tatcggtgac
    41161 aaagtcaatg tccttgtagc aagcaagaca aaagaccttc atgcaggaaa ccttgtcaaa
    41221 gaattagcac caatcatcga tggacgtggt ggtggtaaac cagacatggc catggcagga
    41281 ggaagcaacc aacctaagat ccaagaattg ttggatgcag tagcaggtaa attgtaatca
    41341 agtaaagatc tatccatttg ggtaggtctt tttgtgaata caaaaaagcc aaatccgctt
    41401 ggacctagct tggttattat gagctattag atggtattga ctgcccagac acttacggat
    41461 ctagctgaga cagggaattg tccataacct tcctcatcaa ttgtaacttg accttggtgg
    41521 ttaccaagta aatctacaaa ggtttgatta gtccattctt gaccgacaaa cattgacttg
    41581 ctgttttctt ggtcatttga gataaggact gcgattgggg attgattttc agcacctgaa
    41641 cgtacccaac cgatacagtt agcatggtca aagtagttat tttgttctcc ataggccaaa
    41701 tcttttcgga tggctaggag gcggtcaagg atttctttga aatcttcttg agcatactgg
    41761 cctgaaatcc catagtagtc tccgtaaaag acacatggaa ggccgtcttg gcgtaacaaa
    41821 atgagggcat aggctgctgg cttgaaccat tcttcaacgg tagactcaag ggcttgtcct
    41881 cgttgggtat cgtggttgtc gacaaaagtc acagccttgt caggcttgag ttcaaccagg
    41941 ctatctgtga aaatgccacg aaggtcatag tttgcgccag cttgactggc ttcaaagaga
    42001 ttctgatgga gacgaacatc gacaaggtca aagtgttctt ccgttttttc gagatagtcc
    42061 agattggctt ccttgtctgg gttccaaaat tcaccaaaaa catagaaatc gtcaccgtat
    42121 ttttccttca tatcgcggat gaagttgcgc ataaagaaag agtcaatatg cttaacggca
    42181 tccaaacgga aaccagctac accagtcgtt tccatgaacc aatcagccca gtcatagatg
    42241 ttttggatga cttcaggatg tttaaagtct aggtcggcat acatgaggta gtcgtagttt
    42301 ccgttttcgt tatcgaccaa ttcctcgtta gcccagccct tgttgtcccc ttggatcaga
    42361 taaatcccag acttacggcg tttggcatca tagtctgtac ctgtgaagtg gtaccagtgc
    42421 cagtggaagt cattgtaggt atcttggcga ccatcgaagg taaaactagt ccagccattg
    42481 atggtgaagg gttctccaag ttcaactgta cggtctacag gatccacttc aataacttga
    42541 aaggcttccc tgtgatcagc agcagccttg tggttgagaa ccacatcggc cataggttga
    42601 attccctgcg ctttaagggc ttgaatggct tgaagatagt cttctttgaa accatacttg
    42661 gtgcggacag tccctttttg gttgaactct cctaagtcaa ataagtcata gaccccatag
    42721 ccgacatctt tttcgttggt tgccttgaag gctggtggca tccagacgtg actgatcccc
    42781 agatgagcta ggtgtggagc attttcagcc agacgcgtcc agtgttgacc gtcgtggggc
    42841 agataccatt caaagtattg catgagtgtt tgattttgca taatgtttcc tcttacttgt
    42901 caatcttgtt ctttattcta tcataaagta tctattagcg caaacgtttg cgtaagatag
    42961 aaggaaacta ttttaactac ttaaaataaa gtattgattt ttttgtatca aagtgctagt
    43021 atagcgatat ataatacaga taaagatagg agttgtccca tgattgaatt tcaaaatgtt
    43081 agtaagttgt atggtgataa aaaggccttg agtaatctca atttgcagat tgaaaatgga
    43141 gagattatgg gcttgattgg tcataatggg gctggaaaat cgaccactat aaaatcccta
    43201 gtcagtatca tttcacccag cagtggtcgt attttggtag acggtcagga gttatcggaa
    43261 aatcgcttgg ctattaaacg aaagattggc tacgtagcag actcgcctga cttattttta
    43321 cgcttaacgg ccaatgaatt ttgggaattg atcgcctcat cctatgatct gagtagatct
    43381 gacttggagg ctagtctagc taggctattg aacgtttttg attttgctga aaatcgctat
    43441 caggttattg aaactctttc tcatggaatg cgtcagaaag tctttgtcat cggggcactc
    43501 ttgtctgatc ctgatatttg ggttttggac gaacccttga ctggtttgga tccccaggcc
    43561 gcctttgatt tgaagcaaat gatgaaggag catgcgcaaa aaggtaagac agttttgttt
    43621 tcaactcatg tgctagaggt agctgagcaa gtctgtgatc ggattgctat tttgaaaaag
    43681 gggcatttga tttattgtgg taaggtagag gacttgagaa aagacaaccc agaccagtct
    43741 ttggaaagta tctaccttag ccttgctggt agaaaagagg aggtttcaga tgcgtctcaa
    43801 ggtcattaaa aaattagttg atatcaatat cctctattca tctcaagaag ctaatctggc
    43861 taatctacga aagaagcagg ctaagaatcc tgggaaaaaa gtaaatgttt ccgctagagt
    43921 cctaagttct tacatttttt ccagtctctt gatgctcatc tgttttagta atatagccat
    43981 tcattttcct tttgaggaaa tacctattta ttttagctcg atggttgcta ttttactggt
    44041 gctggccttt tcaacttctt tcactgcatt ttacaatgtc ttttatgaga gtaaggacct
    44101 ggcctcctat aggccctatg cctttaaaga atcagagatt ataatggcca aaggtctgtc
    44161 tgtcctcttg ccagctctag ctggaattgt accaatccta gcttattttc tggtcctcta
    44221 cattaggcta gcaccttctc tgtggttggg tttgcctttg atgctactgt ccttgacctt
    44281 attatttgtc tctgttactt tagtgatggt agtggcagta catttcttgg ctcaaactac
    44341 ggtcttcaga aagtatcagt ctattttttc gaatgtgatg attgggatag gagttctcat
    44401 acctttaata tttatcttct ttcttcagtc gacttttgga agtattgttg acaaagttag
    44461 agacattcca tttctccttt atcctcttca tatcttttac aaaatagcag tggagccttt
    44521 ttcgacagaa gccatattgg gtctgctcgc ttggatagga ctaactctct tcctgcttta
    44581 tctgaccaaa aagaaggtcc ttcctcgttt ttatgacgtg atcctgctta atagtgagga
    44641 gaaggtcaaa aaagaacgtc gcagcaagga gagaatttca accactaaaa agggattttt
    44701 ccgcatggtt ttacgctacc acctcaccct cttgggacag ggtactggcg tggttacagt
    44761 gctttttaca agtgctttct ttccttatct catgatgatc ggtctgattt ccaaaatccg
    44821 agattctcag atagttccag acattcatcc tccatactgg ttacccttgt tttttgtagg
    44881 agtgtttata gcagttgtca ataacaatat caccagcctg cattcaattg ccttgtcctt
    44941 ggagagggaa aatcttgatt ttctgaagag tttacccttt gactttgctc gttatgtgaa
    45001 agtgaaattt tggattatct ttgctgttca gtccttttta ccaattctga ctttgctcgg
    45061 tctttctcta tatctaggct tgtccatcct ttcgatgatt taccttcttg tagtctggat
    45121 cattgccagt gtcatccttt cttgccacca ttactttaag gacgttaaaa atctgtcaac
    45181 caattggagt agcattacgg acctggtgaa tcgttcaaat ggcatagtcg ccatagtttt
    45241 attgtttatt tatagtgcaa tcctgatggc ccttgtaatt gggagcatat tcttggttca
    45301 gtctctctcc cctatccttg ccatcaactt gggagtagga gctcttatcg tcttgcttgc
    45361 tcttgctatt tttggctatc attattacct gtcacgcata ttggcagaaa tagaaaaaag
    45421 atgagatagt tggttgcttg cttgataaat tcaattcgac aaacgctttt atagtttgtt
    45481 agaatgtagt tgtaaatgat taagattggt aatcaaaaat atagggagga atgttttgaa
    45541 taagaaatat aatatagttc tattattgtt gtttatagtt tatttattgg gatatttttc
    45601 aatttcaaaa acgttaattc ctataatgtg tgtgatccaa gtatttttga tagaacatat
    45661 atttagagtt cgaaatagaa tgatgcaaat aggtgaaatt ttaattattg ttgcttctat
    45721 aatattattt attgatagta tattgagttt gtaacaaaag gcttctctat aaaatcaaat
    45781 tttccagata tctattgaag cagatttatt tcttcatctt tcttctacta cctttgtcac
    45841 taaatttgac agacacatat tgctgataca acctctctac ctataatctc acagttaacc
    45901 tgaggctagt ttcatagttt gctatttgat tttcgttgat aataaaaaat gctcctccaa
    45961 gacggaagag cattttttat tgtgattctt acacatttac ttcctagttt tgcaggaagt
    46021 ctagtatacc attttttaaa agaagagtaa aaaagcaagg gtagtttctt ttttgagaat
    46081 tgtctaaaag tttgatataa tggtagttat gaatagaata agagtcagca aaagggttga
    46141 aaagaagctt gctaaggggc tagttttact agaagccagt gatcttgaga atgtcaatct
    46201 taaggatcag gaagtagagg tgcagggtca ggaaggaaac tttcttggga ctgcctacct
    46261 ttctcagcaa aacaagggct tgggctggtt tgtcagcaaa gacaaggtgg ccttcaatca
    46321 agctttcttt gaaacgttgt ttagaaaagc caaagaaaag agaagcgcct actatcaaga
    46381 tgatttaaca actacctatc gtctctttaa tcaagaggga gatggctttg ggggtctgac
    46441 agtggacctt tatggcgact acgccgtctt ttcttggtat aactcttatg tttatcagat
    46501 tcgtcagact atatcagaag cctttagaca ggttttccct gaggttttag gggcttatga
    46561 gaaaattcgc tttaagggtt tggactatga atctgcccat gtttatggtc aagaagcacc
    46621 tgactttttc actgttttag aaaatggtgt cctgtatcaa gtctttatga atgatggctt
    46681 gatgacagga attttcctag accagcatga ggttcgcggt agtttagttg acggcttggc
    46741 tatgggtaaa tccttgctca atatgttttc ctacacagcg gctttttcag tagctgcggc
    46801 catgggagga gctagccaga caacttctgt tgatctagcc aaacgttcac gagaattgtc
    46861 tcaagcgcat tttcaggcaa atgggctcag cacagacgag catcgtttta tagtcatgga
    46921 tgtctttgag tatttcaaat atgccaaacg caaaaacttg acctacgatg tgattgtcct
    46981 agatccgcct agctttgctc ggaataaaaa acaaactttc tctgtggcca aggattatca
    47041 caagttgatt tcccagagtc ttgagatttt aaatccggga gggattatca ttgccagtac
    47101 caatgctgcc aatgtttccc gtcagaaatt tacagaacaa attgataaag gctttgcagg
    47161 aagaagttac cagattttaa acaaatatgg tcttccagca gattttgcct ataataaaaa
    47221 agatgaaagt agtaattacc tcaaggtgat tagtatgaag gttagtaaat gaaattaatc
    47281 gtttcagtaa tgccaagaag tttagaggag gctcaggctc tggatgccac gaggtacctg
    47341 gatgccgaca tcattgaatg gcgtgccgac tatctgccta aagaagcgat tttgcaggta
    47401 gctccagcca tttttgaaaa attcgcaggc cgtgagttgg ttttcacgct acgaactcgc
    47461 tccgaaggtg gagaaatcga cctttctcca gaagagtata tccatctaat caaggaagtt
    47521 gcgcaactct atcaaccaga ctatattgat tttgagtact atagctacaa ggatgttttt
    47581 gaggaaatgc tggacttccc aaatcttgtt ttgagttacc ataatttcca agaaacacct
    47641 gagaacatga tggaaatctt gtcagagttg acgatcctaa atccaaaact tgttaaggtt
    47701 gcggtgatgg ctcacacgga gcaggatgtc ttagacttga tgaactatac acgaggcttt
    47761 aaaaccctca atcctgaaca ggaatatgtg accatttcta tgggtaaggt gggcaaggtc
    47821 tctcgtatca ctgcggatgt gactggttcg agttggtctt ttgccagtct ggatgaggtt
    47881 agtgcccctg ggcagatttc tctagctagc atgaaaaaaa tcagggagat tttggatgaa
    47941 gcttgatggc tatacacgtt tagctgcagt tgttgccaat cctattaagc attctatttc
    48001 tcccttcatc cacaatagag cctttgaggc gacagctacc aacggtgctt atgtggcttg
    48061 ggagattgaa gcgagtgact tggtagaaac agtggccaat attcgtcgct accagatgtt
    48121 tggcatcaat ctgtccatgc cctataagga gcaggtgatt ccttatttgg ataagctgag
    48181 cgatgaagcg cgcttgattg gtgcggttaa tacggttgtc aatgagaatg gcaatttaat
    48241 tggatataat acagatggca agggattttt taagtgcttg ccttctttta caatttcagg
    48301 taaaaagatg accctgctgg gtgcaggtgg tgcggctaaa tcaatcttgg cacaggctat
    48361 tttggatggc gtcagtcaga tttcggtctt tgttcgttcc gtttctatgg aaaaaacaag
    48421 accttaccta gacaagttac aggagcagac aggctttaaa gtggatttgt gtgctttaga
    48481 atatgtttct gaactgcaag caaggattgc cgagtcggat ttgctagtta atgccaccag
    48541 tgtgggcatg gatggccaat cctctcctgt tcctgaaaac atagtcttac cagaaactct
    48601 tttagttgca gatatcatat accaaccctt tgaaacaccg tttttgaaat gggctagaag
    48661 tcagggcaat ccagcagtca atggtctggg aatgttgctc tatcaagctg cagaagcttt
    48721 tcaactgtgg acaggcaagg aaatgccgac agaagagatt tggcagtctt taacagaaaa
    48781 ataccaataa agaaagggag actctcctat gaaaatcaga atcgatattc ctcatcatcc
    48841 ttatgatatt cagattgaaa aaggttgtat ggcccaggct ggtcagtggt tgcgagaact
    48901 ctggcaaccg caaaaggtag tcattgtgac agataaccat gtagcctctc tctatgcaga
    48961 gaaggtcaag ctcagcctag aagatgctgg ttttcaggta gctgtttttg atttcttaga
    49021 aggtgaagaa agaaagaatt taactactgt tcagaaagtc tatgaatttc tagtcaagca
    49081 aggtctgact cgtagcgatg gaatcgttgc tcttggtggt ggcgttgttg gggacctggc
    49141 tggctttgta gcctctacct atatgcgggg tattcacttt gttcagattc cgactagttt
    49201 gacagctcag gttgattctt ctatcggtgg aaagacaggc gttaacacac catttgctaa
    49261 aaatatggtg gggacctttg cccaaccaga tggggttctg attgatccac ttgttcttga
    49321 aaccctcgga aaaagagagt tgattgaagg gatgggtgaa gttatcaagt atggcttgat
    49381 tgaggatcca gaactgtggg ctctcttgac gggactgaat ggttctgttg agagtatttt
    49441 ggaacatgca gagaccttga ttgaacattc ttgtcaggtg aagcgcaaga tggtggttga
    49501 agatgagttg gacaatggta ttcgtcttta cctcaatttt ggccacacta ttggccatgc
    49561 catcgaagcg actgccggtt atggcaaggt catgcatgga gaggctgttg ccatgggaat
    49621 ggtacagatt tccaaggttg ctgaggaaaa aggcctcatg ccagctggca ttacccaatc
    49681 tatcacagag atgtgtcaga aattcggctt gcctgttgac tatgaaaatt ggaaagttga
    49741 caagctttat caggctctta ctcatgacaa gaaagcgcgt ggtaacacct tgaaattggt
    49801 cttggtgcca gagcttggtt cagcgaccat tcacccagtt tctctggaag agatgaaaga
    49861 ctacttggta aaataaggag agtgtatgag atatttaact gcaggagaat cacacggccc
    49921 ccgtctaaca gctattattg agggaattcc agctggactt ccattgacag ctgaggatat
    49981 caatgaggat cttagacgcc gtcagggtgg ctacggtcgt ggtggtcgta tgaagattga
    50041 gagtgaccag gttgtcttta cttcgggtgt tcgccacggg aagacgacag gggcgcctat
    50101 tactatggat gtcatcaata aggaccacca gaaatggctg gacatcatgt ctgcggagga
    50161 cattgaagac cgccttaaaa gcaagcggaa aattactcat cctcgcccag gtcatgccga
    50221 tttggttggg gggattaagt accgttttga tgatttgcga aattctttgg agcgttcatc
    50281 agctcgtgaa accaccatgc gggtggcagt tggtgcagta gccaaacgcc tcttggctga
    50341 gctggatatg gagattgcca accatgtcgt ggtctttggt ggtaaggaaa tagatgttcc
    50401 tgaaaatctg acagtcgctg aaattaagca aagagctgcc cagtctgaag tttctattgt
    50461 caaccaagaa cgagaacagg aaatcaagga ctatattgac caaatcaaac gtgatggtga
    50521 taccatcggt ggggttgtgg agacagtcgt cggaggagtt ccagttggtc ttggttccta
    50581 tgtccaatgg gatagaaaat tggatgcaag attggctcaa gctgttgtct ctatcaatgc
    50641 ctttaaaggg gtggaatttg gtcttggctt tgaggctggt tatcgtaaag gcagccaagt
    50701 tatggatgaa attctctggt ctaaagaaga cggttatact cgccgtacca ataatctagg
    50761 tggttttgaa ggtggtatga ctaatgggca acccatcgtt gttcgtgggg tcatgaaacc
    50821 cattcctact ctttataaac ctcttatgag tgtggatatc gaaacccacg aaccttacaa
    50881 ggcaaccgtg gagagaagtg atccgactgc tcttccagct gcaggaatgg tcatggaagc
    50941 agttgtagca acggttctgg cgcaagaaat cctcgaaaaa ttctcatcag ataatcttga
    51001 ggaactaaaa gaagcggtag ccaaacaccg agactataca aagaactatt aaggagttcc
    51061 tatggcaaaa acaatctata tcgcaggtct tgggttgatt ggagcctcta tggcacttgg
    51121 tatcaaacgc gatcatccag attatgaaat tttaggttat aatcgtagtc aagcttcgag
    51181 agatatcgcc ttgaaagaag gtatgattga ccgtgcaacg gatgattttg ctagttttgc
    51241 tcctttggca gatgtcatta tcctcagctt gccaatcaaa caaactattg ctttcattaa
    51301 ggagttggcc aatttggatt tgcgagaagg cgttattatt tcagatgctg gttcgaccaa
    51361 gtcaaccatt gtggatgcgg cggagcagta tttggctggc aagtctgttc gctttgtcgg
    51421 ggcccatccc atggctggta gtcacaagac aggggctgct tcggcagatg tcaatctttt
    51481 tgaaaatgcc tattatatct ttacaccttc aagcctgaca agtcaggaca cgcttaagga
    51541 aatgaaggat ctgctttcag gtcttcatgc tcgttttatc gagattgatg ccaaggagca
    51601 tgatcgtgtc acttctcaga ttagccattt tcctcatatt ttggcttcta gtctcatgga
    51661 gcagactgcg gtctatgctc aagagcatga gatggcaagg cgctttgcgg caggtggttt
    51721 tcgagatatg acccgaattg cggaaagcga gccaggaatg tggacctcca ttctcttgtc
    51781 caatagcgag accattctgg atagaattga ggatttcaag gaacgtttgg aagtgattgg
    51841 tcaggccatt agtaagggag atgaagagca aatttggaac ttttttaacc aagcgcgtga
    51901 acaacgccag accatggaaa tccataagcg tggtggtgtg gatagctctt acgacctcta
    51961 tgttgacgtt cctgatgaag aagatgtcat cctgcggatt ttggaactgc tacgtggaac
    52021 ttccttggtt aacatccaca tcaacgagga aaatcgtgag gatattcacg gaatcctaca
    52081 aatttcattt aaaaatgctc aagacttgga aagagctgag catctcataa cagaaaatac
    52141 cgactataca gtcgtcatca aataaggaga agaacatgtc aaatatttac gatagtgcaa
    52201 acgaactcag tcgcggtcta cgcggattac cagaatacaa ggctgttaaa gcagctaaag
    52261 atgcgattgc agcagatgct gaggcaagca aaatctttac agaatatctt gcctttcaag
    52321 aggaaattca aaaactagca cagacaggtc aaatgccaga tgcgtccttc caagctaaga
    52381 tggaaggctt tggtaaacag attcaaggaa atagcctctt gtcagaattc tttaccaagc
    52441 aacaacaatt ggccatttac ctttctgaca ttgaaaaaat tgtttttgaa ccagtttcag
    52501 aattgctgaa ataagaaaag aacgatccta aagtcaggaa tttttaagga atttctgact
    52561 ttttatgata aaataggtaa aagtattgca agtatgaggt ccagtatgaa actaaaaaca
    52621 aacattcgcc atttacatgg tagtatccgc gtcccaggtg acaagtctat cagccaccgt
    52681 tccattatct ttggaagttt ggctgagggt gagaccaagg tttatgatat tctgcgaggt
    52741 gaagacgttc tttcgaccat gcaggttttt cgtgaccttg gtgttgaaat tgaggataaa
    52801 gatggggtta ttaccattca aggtgtaggc atggctggct taaaagcgcc gcaaaatgcc
    52861 cttaatatgg gaaattctgg cacctcgatt cgcctgattt caggtgtcct tgctggtgca
    52921 gatttcgaag tagagatgtt tggagatgat agtctttcca aacgtcctat ggaccgtgtg
    52981 acccttccac tgaaaaaaat gggcgtcagc atttcagggc aaactgaacg agacttgcct
    53041 ccccttcgct taaaagggac gaaaaaccta agacctattc attatgagtt gccaattgcc
    53101 tctgcccaag tcaagtcagc cttgatgttt gcagccttac aagctaaggg ggcgtcagtt
    53161 attatcgaaa aagagtgcac ccgtaatcat actgaagata tgttgaaaca atttggtggt
    53221 catttaagtg tggacagtaa gaaaatcaca gtccaagggc cacaaaaatt gacaggacag
    53281 aaggtggtcg taccaggaga tatttccagt gcagcctttt ggttagtcgc aggtttgatt
    53341 gttccaaatt ctcgtctagt gctgcagaat gtggggatca acgaaactcg caccggtatt
    53401 attgatgtca ttcgtgccat gggtggaaaa ttggaaataa ctgaaatcga tccagtcgct
    53461 aaatcttcta ccttgactgt tgagtcttct gacttgaaag gaacagagat tggtggcgct
    53521 ttgattccac gattgattga tgaattgccc attattgccc tgcttgcgac tcaagcccaa
    53581 ggtgtaacag ttatcaagga tgctgaggag ctcaaggtca aggaaacaga ccgtattcag
    53641 gttgtggcag acgccttaaa tagtatggga gcagatatta ctcctacggc agatgggatg
    53701 attatcaaag ggaaatcagc tcttcacggt gctagagtca atacgtttgg tgaccaccgt
    53761 atcggcatga tgacagctat cgcagccctc ttggttgcag atggagaggt ggagcttgac
    53821 cgtgcagaag ccatcaatac cagctatcct agtttctttg atgatttgga gagcttgatt
    53881 catggctaag gtgttattag ggtttatggg ggctggaaaa tcgactattg caagaggctt
    53941 ggaccctaat taccttgata tggatgctct gattgagaag cgcctaggta tgtccattgc
    54001 gaattttttc gctgaaaagg gagaagcagc ctttcgtcag gtagaatcag aagtcctagc
    54061 tgatttacta caaacagacc aagtcgtgtc aactggagga ggagtggtta tttctcagag
    54121 aaatcgtgac ttactcaaga ctaatacaga taacatctac ctgaaagcag attttgaaac
    54181 cctctaccta cgtatcgtag ctgataagga caatcagcga ccgctttttc taaataatag
    54241 caaggaagaa ctagtagcta tttttcaaga aagacaggct tggtatgagg aagtggctag
    54301 tcgggttttg gatgtgacca agctaagccc agaggaaatt atagaggaac taagatgaaa
    54361 attgcttatc taggtcccaa gggatcattt tcacaccacg ttgtgcagac agcttttcct
    54421 catgaggaat tgcaggcttt tgccaacatt acagatgtca tcaaggctta tgagcaagga
    54481 ttagtgaact attctgtggt gccagttgaa aattctattg agggtagtgt tcatgaaacc
    54541 ttggactatc tttttcatca ggctcacatc caagcagtag cagaaatcgt tcagcctatt
    54601 catcagcagt tgatggtggt tccaggccat actaagattg aaaagatttt ttcacatcca
    54661 caggccttgg ctcaaggaaa gaaattcatc gatgaacaat atccagaggc tcaaatcgag
    54721 gtaacagcta gtacagctta tgcggcccgt tttatttccg aacatccaga ccagcccttt
    54781 gcagcagttg cacctagaag ttctgctgaa gaatatggat tggaactgat tgccgaggat
    54841 attcaggaaa tggaagccaa tttcacacgt ttctgggttc taggagctga aaatcctagt
    54901 attcccttgc aagcacaaac tgaaaagatg agtttggcct tgacattacc tgacaacctt
    54961 ccaggtgcac tttataaggc cctgtcgacc tttgcttggc gaggaattga cttgacaaaa
    55021 attgaaagtc gtccactcaa gacagcactg ggtgaatact ttttcattat cgatgtggat
    55081 tataccgata aggacttggc ccactttgcc caaaaagaat tagaagcgat tggaatccag
    55141 tataaaattc tgggtgccta tcctatttat ccaatatcag accatggaaa ggagagaaga
    55201 tgagtaaaga aaatccctta agtcatcatg agcagttgcg ttatgattat ttgctaaaaa
    55261 atattcacta tctcaatgag agagaaaaaa atgagtttgc ctatttgcaa gaaaagctaa
    55321 ctcttgctag gggaaatagt agctctagct tggaacaaga aagagaagag caggttgact
    55381 taccaagcta tgcgaaccgg agtcgctcac aatccaaatc acaagcactc tcttcccctc
    55441 caaaaaagaa aagacggaag ctccgtctta aacgaatttt tatggtgatt ttttcacttt
    55501 tggtctgtgt ggctttggcc atggtattca tgtttttgcg tggttaccaa gatgctagcg
    55561 caaagaaaac tgctgatgct cgggcagctc aagtagaagt ctttaatggt caggacacta
    55621 gagatggagt taatatttta atcatgggta ctgatggtcg aatcggccag aacagtgttg
    55681 agacacgaac tgactctatt atggtattaa atgtcggggg ctcagataag aaaatgaagc
    55741 tagtcagttt catgcgtgat aatttggtct atatagatgg ttatagtcaa gtgattaatg
    55801 gtagaaaaca gacagataac aagttaaacg tagcctacga gttaggagaa caagaggggc
    55861 aaaaaggggc agaaatggtt cgccaagtct tgaaagataa ttttgacttg gacattaagt
    55921 actacgcctt ggttgatttc caggcctttg ccacagcgat tgacacgctt ttccctgatg
    55981 gggtgacgat tgatgctcaa ttttcaacat tgaatgggcg tcccctaaca gaagctacag
    56041 tcggagatga tttatacgct accgagactg agtctccaac ccaaaccatt aaagtcggaa
    56101 aacagcagat gaatggctcg accctgctca attatgctcg tttccgtgat gatgatgagg
    56161 cagattacgg ccgtacaaaa agacagcaac aagttttaac agcaatttta gagcaaatta
    56221 aagatcccac taaacttttc actggttctg aagctcttgg aaaggttttt gctatgacct
    56281 caaccaacgt accctatact ttcctcctaa caaacggttt atctgttttg gatggagcaa
    56341 aaaatggtat tgaaaaattg acgattccag aactgggtga ctgggtagat gcctatgatg
    56401 tttatggagg cttgggcttg ctggttgatc aaaacaaata tcaaaccaag ctcgctcaaa
    56461 tgggcttgag ataagataat actcaatgaa aatcaaagtg caaactagga agctagccgc
    56521 aggctgctaa aaacacagtt ttgaggttgt agataagact gacgaagtca gttacctata
    56581 cctacggcaa ggtgaagctg acgtggtttg aagagatttt cgaagagtat aagacagaaa
    56641 aatcaaagtt tgatagctat ttggatagca gtcaggcttt gattttttac agtctgcaat
    56701 agattttcac cccttgtttg tggtataatg aaacgatacg atagaaagaa taatgaacaa
    56761 tatgactgat ttaaaagcaa ttcaggctcg tagtctggag atggctgaat attttgtggc
    56821 cttttgtaaa gaacatgatt tgctctgtta tctctgtggc ggaggcgcta ttggtgccct
    56881 tcgaaacaag ggatttattc cttgggacga cgacctagac ttttttatgc ctcgtaaaga
    56941 ttatgagaaa ttagcagaat tatggcctcg ttatgcagat gaacgttatt tcttgtcaaa
    57001 gagtcacaag gattttgttg atcgtaatct ttttattacc attcgtgaca agaaaaccac
    57061 ctgtatcaag ccttatcagc aggatttgga tttgccacat ggtctggcct tggatgtttt
    57121 gcctttggat tattatccga aaaatccagc tgagcggaaa aaacaggttc gttgggcctt
    57181 gatttattca ctcttttgtg cgcaaactat tccagaaaag catggtgctc tcatgaaatg
    57241 gggaagttgc attttactgg gtttgactcc aaaatctctc cgttatcgca tctggaaaaa
    57301 agctgagaaa gaaatgacta agtatgattt ggctgattgt gatggcatta cagaattatg
    57361 ctcaggtcct ggctacatga gaaacaagta cccaatcaca tcttttgaag acaatctttt
    57421 cttgccattt gaaggaacag agatgcctat tccaatcggc tatgatgtct atctcagaac
    57481 tgcttttggg gattatatga cgcctccacc agcagacaag caggtaccgc atcatgatac
    57541 tgtcattgct gatatggata agtcttatac agaatacaag ggagaatatg gtggctaaga
    57601 aaaaaatctt attttttatg tggtcttttt ctcttggagg tggtgcagag aagattctat
    57661 caaccattgt ttcaaatctg gatccagaaa agtatgatat tgatattctt gaaatggagc
    57721 actttgacaa gggatatgaa tctgttccaa agcatgtacg cattttaaaa tcccttcaag
    57781 attatcgcca aaccagatgg ttacgagctt ttttgtggag aatgagaatt tattttccaa
    57841 gactgactcg tcgtttgctt gtaaaagatg attatgatgt tgaagtttct tttaccatta
    57901 tgaatccacc actgttgttc tctaaaagaa gagaagtcaa gaagatatct tggattcatg
    57961 gaagtattga agaacttctt aaggatagct ctaaaagaga atcacataga agccagttgg
    58021 atgctgcgaa tacaattgta gggatttcaa aaaagaccag caattctatc aaggaagttt
    58081 atccagatta tgcttctaaa ttacagacaa tctacaatgg atatgatttt cagactattc
    58141 tagaaaaatc tcaagagaag atcgatatcg agattgctcc tcaaagtatc tgtactatcg
    58201 gacggattga ggaaaataag ggttctgacc gtgtagtgga agtgatacga ttattacacc
    58261 aagagggaaa aaactatcat ctctatttta tcggggctgg tgatatggaa gaggaactga
    58321 aaaaacgagt caaagagtat gagattgagg actatgtaca tttccttggt tatcaaaaaa
    58381 atccttatca gtatttatct cagacgaaag ttctcttgtc tatgtctaaa caagaaggtt
    58441 ttcctggagt gtatgtggag gccttgagtc tgggactccc ttttatctct acggacgttg
    58501 gaggggctga ggaattatcc caagaaggac gatttggaca aatcattgag agcaatcaag
    58561 aggcagctca ggcgattact aattacatga cttctgcctc aaactttgat gtcgatgagg
    58621 ctagccaatt cattcaacaa tttacaatta caaaacaaat cgaacaagta gaaaaactat
    58681 tagaggagta gcatggaaac tgcattaatt agtgtgattg tgccagtcta taatgtggcg
    58741 cagtacctag aaaaatcgat agcttccatt cagaagcaga cctatcaaaa tctggaaatt
    58801 attcttgttg atgatggtgc aacagatgaa agtggtcgct tgtgtgattc aatcgctgaa
    58861 caagatgaca gggtgtcagt gcttcataaa aagaacgaag gattgtcgca agcacgaaat
    58921 gatgggatga agcaggctca cggggattat ctgattttta ttgactcaga tgattatatc
    58981 catccagaaa tgattcagag cttatatgag caattagttc aagaagatgc ggatgtttcg
    59041 agctgtggtg tcatgaatgt ctatgctaat gatgaaagcc cacagtcagc caatcaggat
    59101 gactattttg tctgtgattc tcaaacattt ctaaaggaat acctcatagg tgaaaaaata
    59161 cctgggacga tttgcaataa gctaatcaag agacagattg caactgccct atcctttcct
    59221 aaggggttga tttacgaaga tgcctattac cattttgatt taatcaagtt ggccaagaag
    59281 tatgtggtta atactaaacc ctattattac tatttccata gaggggatag tattacgacc
    59341 aaaccctatg cagagaagga tttagcctat attgatatct accaaaagtt ttataatgaa
    59401 gttgtgaaaa actatcctga cttgaaagag gtcgtttttt tcagattggc ctatgcccac
    59461 ttctttattc tggataagat gttgctagat gatcagtata aacagtttaa agcctattct
    59521 cagattcatc gttttttaaa agaccatgcc tttgctattt ctaggaatcc aattttccgt
    59581 aaggggagaa gaattagtgc tttggcccta ttcataaata tttccttata tcgattctta
    59641 ttactgaaaa atattgaaaa atctaaaaaa ttacattaga acgggggtga ccaagtgatt
    59701 gatgggaaac gattattatt tagtttgacc atagtcagtt atgccttgac gctagtaagt
    59761 ggaattgtgt atctgtttaa taataataat gttagcttac tttctacttt attgttcttg
    59821 ttggttagta gcttaattgc ttgttggaat gatatcaagt attacttaat ccattttatt
    59881 ttctatttaa ccatttttgt atttctggta tcaagaccga ccattgatta ttttagggat
    59941 ggtgctttgg atacctatca tccaatagcc tatcgttttg cctttatagt tgtcatggtt
    60001 tcgattctgg gcttgaccac aggaggcatt ctggctcgtt acttcatagc taggaagaaa
    60061 ataaaagtag caaatatagg aaattctcta aaagaggttt atatcaagcg gttacgcttt
    60121 gtatcactag gagtttttct tctaacctat cctttctatt tcattcggtt atttgaacgg
    60181 ctcttgtatc gtttgcagac ttcctactat gcctactatg caaattttga aagtaaactg
    60241 ccttatttta cctacatttt gtctaccttt acggtctatg caatgtgtat gtatctggca
    60301 accaagccaa agaaattgca ggccacagca gtgcttgtct cctttattgc agctaatact
    60361 attcatttgg caattgggac acgaaatccc tttattttaa gtattttatt tgcttttgtt
    60421 tattacttta tgcgggagca aactgaaaaa ggaaaatgga ttgggtttaa agaaaagtta
    60481 gcgatttttg taggttctcc tattctcatg ttagcgatgg gagtacttaa ttatgtacgg
    60541 gataatgtcc aagtttccca tacaggtttc tgggatatct tacttgactt tatctataaa
    60601 caaggaacta gttttggtgt tctggctcga ggttttctat ttaacagtag cctcccttac
    60661 cgagatttcc gtaattttac ttttggtcct gttcttgatt attttgcaag ggggagtttg
    60721 ggagccattt tcggaggaaa agcctttgaa catacaacca atagtgtgga actagctatt
    60781 gatagtaata gttatgccca caatctatcc tatcttgtct tgaacaagga atacttgaaa
    60841 gggcatggta tcggaagtag ttatatcatg gagttgtata ccgactatgg tatgattgga
    60901 gtctttctgc ttagtttctt actcggcgta ttatttatag ccatgctgca agtagcctat
    60961 cgctcaagga caatcctatt tgctttatcc ctactcatct tgaataatct attctttatg
    61021 ccaagaagca gcttttcaga aagtttcttc aatttattta caatgcaatt ctggggaatt
    61081 gttcttgtga ttatatttgt agcaaaaatg cttacaaagg aaaactagta tctactaaac
    61141 aaaggagaaa aaaatcatgt ttgaacatta ttcagtagct gatttgtttg caaatcttta
    61201 taaaaaacga aaagcaaata ttttagctct catcgcttta tttgctctca ttgctgtacc
    61261 atttacaatt aaagcagtta ggaataaaaa cactgtcaaa gatacaacaa gttattcaac
    61321 ttatcttatc tataaaatca ctcctccaga agattcggcc aaaacgattt tgaatcatca
    61381 aattggtggt tatagtgatt tttatgggaa attgattgat ggtaatttga atggagctta
    61441 tcttttcaat gatgtagaac ccagtgagtt gaaaaaaatt gccagtgaat tagacacgac
    61501 ggaaacaacc ttgaaaaatt caacgaatga ctattggtgg aaaaaattga ccgtctacta
    61561 tatgattgac gatgcagggg ttggtgtgaa aattttgaca tcaagtaaag atgccaatga
    61621 cttgttagag aaaaaaattg atgggttgat tgagaaattt aaacatgctt atgcaaatgt
    61681 gaaaattgaa aaactggaaa ccatcaactc taaagaattg aacgcaaatg gtgaaacagc
    61741 gcttggctta aatgtgaaaa atctgattct tcgtttagtt gttattggag tggtttgtgt
    61801 gattttggtt gtgatgggaa atgtgttagt ttatctcttt aatccaacaa tcaatagagt
    61861 aggtgatttt tctcagtatc aaattgattt tgtaacagag attacaacaa ttgctaacct
    61921 agcagatgtt ttgtcataca aaaatactgg acaggaattg accatcgtta gctcaaataa
    61981 agctatccta gataaattga aacagagtca agaagcttta aaaggaatgc attttgtaga
    62041 tttgcaggat gtatcatctc ttttggaaag agatacagtc cttcttgttg aagagtacgg
    62101 agtgactcgt tataagaaat ttgagcaaag tcttcaaatt ctcagaaact taaatcgttc
    62161 tatcctcggt gtagcaacct ttaaattata agtattctga tgtataaggt cttcaaaatc
    62221 ggctcttagc cgattttgaa ggctttttct atctgtctgc agaaattttc tcttggagtc
    62281 tcctatagaa agaccctagg gaaaatctat ccgtatagag gagccttctt ttgataaaat
    62341 cgtaaaaatc tagtataata gatagaactg aaagtatgag gttactagca atgaaaatga
    62401 aacaaattag tgatacaact ttaaaaatca cgatgtcttt agaggatttg atggatcgtg
    62461 gaatggagat tgctgacttt ctcgttcctc aagaaaaaac agaagagttc ttttatgcta
    62521 tcttggatga gctagagatg cctgatagct ttctggatac aggcatgttg agcttccgtg
    62581 tgactccaaa acctgataag gtagatgtct ttgtgaccaa gtcaaagatt gaccaaaatc
    62641 tagattttga agacttatcg gatttgccag atatggaaga attggctcaa atgtctccag
    62701 atgaatttat caaaaccctg gaaaaaagca tcgcagacaa aaccaaggat gatatcgaag
    62761 ccattcaatc tcttgagcaa gttgaagcca aggaagaaga gcaagagcag gctgaacaag
    62821 aagctgagag taagaaagaa ccttacatct actacatcct ttcttttgct aagttggctg
    62881 acttggtagc ttttgccaag acagtgactt ttgaaatgga aacttctgaa ctctacaaaa
    62941 tgaacgagcg ctattatttg accattttag tggatattga aaatcatcca agcccatatc
    63001 cagcttggct gttggcccgt atgcgcgagt ttgcagacga tagtgatatc agtcgctcag
    63061 tcttacaaga gtatggtcaa gtcttgatga gtcacgatgc agtgctcaat ctgcaaaaaa
    63121 tcggctaatc ctttctggaa agctattttc agattttaag aagagcgaat cgtctgattc
    63181 gttttttctt tttatactga aatagtgatt tactataata ggaattttca caaaattctg
    63241 ttataatggc tatattagaa aatttcgagg agataaagat gacagttaaa attgctttac
    63301 taggatttgg taccgttgca agtggtgtgc ctttcctcct aaaggaaaat ggaggaaaaa
    63361 tcaatcaatc agcacattca gatatcaaag ttgctaaggt attggtcaag gatgaagatg
    63421 aaaaaaatcg cttgcttgca gcagggaatg actttaactt tgtaaccaat gtggatgata
    63481 ttttatcaga ccaggatatt actatcgtag tggaattgat ggggcgtatt gagcctgcta
    63541 aaacctttat cacttgtgcc ttggaagctg gaaaacacgt tgttactgct aacaaggacc
    63601 ttttagctgt ccatggcgca gaattgctag aaatcgctca agctaacaag gtagcacttt
    63661 actacgaagc agcagttgct ggtgggattc caattcttcg tactttagca aattccttgg
    63721 cttctgataa aattacgcgc gtgcttggag tagtcaacgg aacttccaac ttcatggtga
    63781 ccaagatggt ggaagaaggc tggtcttacg atgatgctct tgcggaagca caacgtctag
    63841 gatttgcaga aagcgatccg acgaatgacg tagatgggat tgatgcagcc tacaagatgg
    63901 ttattttgag ccaatttgcc tttggcatga agattgcctt tgatgatgta gcccacaagg
    63961 gaatccgcaa tatcacacca gaagacgtag ctgtagctca agagcttggt tacgtagtga
    64021 aattggttgg ttctattgag gaaacttctt caggtattgc tgcagaagtg actccaacct
    64081 tcctacctaa agcgcaccca cttgctagtg tgaatggcgt aatgaacgct gtctttgtag
    64141 aatctatcgg tattggtgag tctatgtact acggaccagg tgcgggtcaa aaaccaactg
    64201 caacaagtgt tgtagctgat attgtccgta tcgttcgtcg tttgaatgat ggtactattg
    64261 gcaaagactt caacgaatat agccgtgact tggtcttggc aaatcctgaa gatgtcaaag
    64321 caaactacta tttctcaatc ttggctctag actcaaaagg tcaggtcttg aagttggctg
    64381 aaatcttcaa tgctcaagat atttccttta agcaaatcct tcaagatggc aaagagggtg
    64441 acaaggcgcg tgtcgttatc atcacacaca agattaataa agcccagctt gaaaatgtct
    64501 cagctgaatt gaagaaggtt tcagaattcg acctcttgaa taccttcaag gtgctaggag
    64561 aataagatga agattattgt acctgcaacc agtgccaata tcgggccagg ttttgactcg
    64621 gtcggtgtag ctgtaaccaa gtatcttcaa attgaggtct gcgaagaacg agatgagtgg
    64681 ctgattgaac accagattgg caaatggatt ccacatgatg agcgtaatct cttgctcaaa
    64741 atcgctttgc aaattgtacc agacttgcaa ccaagacgct tgaaaatgac cagtgatgtc
    64801 cctttggcgc gcggtttggg ttcttccagc tcggttatcg ttgctgggat tgaactagcc
    64861 aaccaactgg gtcaactcaa cttatcagac catgaaaaat tgcagttagc gaccaagatt
    64921 gaagggcatc ctgacaatgt ggctccagcc atttatggta atctcgttat tgcaagttct
    64981 gttgaagggc aagtctctgc tatcgtagca gactttccag agtgtgattt tctagcttac
    65041 attccaaact atgaattacg tactcgcgac agccgtagtg tcttgcctaa aaaattgtct
    65101 tataaggaag ctgttgctgc aagttctatc gccaatgtag cggttgctgc cttgttggca
    65161 ggagacatgg tgaccgctgg gcaagcaatc gagggagatc tcttccatga gcgctatcgt
    65221 caggacttgg taagagaatt tgcgatgatt aagcaagtga ccaaagaaaa tggggcctat
    65281 gcaacctacc tttctggtgc tgggccgaca gttatggttc tggcttctca tgacaagatg
    65341 ccaacaatta aggcagaatt ggaaaagcaa cctttcaaag gaaaactgca tgacttgaga
    65401 gttgataccc aaggtgtccg tgtagaagca aaataaagaa tagaagatag gatggggaaa
    65461 ctcttgacca gagggtttca tatccttttt gtgaaaagaa gtttatactc aatgaaaatc
    65521 aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac agtgttttga ggttgtggat
    65581 agaactgaag aagtcagctc aagacactgt tttgaggttg cagatagaac tgacgaagtc
    65641 agtaacatat atacggtaag gtgacgctga cgtggtttga agagattttc gaagagtatt
    65701 agttaaaaac gtgataaagg agaaataaag atggcagaaa tttatctagc aggtggttgt
    65761 ttttggggcc tagaggaata tttttcacgc atttctggag tgctagaaac cagtgttggc
    65821 tacgctaatg gtcaagtcga aacgaccaat taccagttga tcaaggaaac agaccatgca
    65881 gaaacggtcc aagtgattta cgatgagaag gaagtgtcac tcagagagat tttactttat
    65941 tatttccgag ttatcgatcc tctatctatc aatcaacaag ggaatgaccg tggtcgccaa
    66001 tatcgaactg ggatttatta tcaggatgaa gcagatttgc cagctatcta cacagtggta
    66061 caggagcagg aacgcatgct gggtcgaaag attgcagtag aagtggagca attacgccac
    66121 tacattctgg ctgaagacta ccaccaagat tatctcagga agaatccttc aggttactgt
    66181 catatcgatg tgaccgatgc tgataagcca ttgattgatg cagcaaacta tgaaaagcct
    66241 agtcaagagg tgttgaaggc cagtctatct gaagagtctt atcgtgtcac acaagaagct
    66301 gctacagagg ctccatttac caatgcctat gaccaaacct ttgaagaggg gatttatgta
    66361 gatattacga caggtgagcc actctttttt gccaaggata agtttgcttc aggttgtggt
    66421 tggccaagtt ttagccgtcc gatttccaaa gagttgattc attattacaa ggatctgagc
    66481 catggaatgg agcgaattga agttcgttct cgttcaggca gtgctcactt gggtcatgtt
    66541 ttcacagatg gaccgcggga gttaggcggc ctccgttact gtatcaattc tgcttcttta
    66601 cgctttgtgg ccaaggatga gatggaaaaa gcaggatatg gctatctatt gccttactta
    66661 aacaaataaa acagagagtg gggcttccca ctttcttcat ttctagaata tgaatagaag
    66721 ggatttatga aacacctatt atcttacttc aaaccctaca tcaaggaatc aattttagcc
    66781 cccttgttca agctgttaga agctgttttt gagctcttgg ttcccatggt gattgctggg
    66841 attgttgacc aatctttacc tcagggagat caaggtcatc tctggatgca gattggcctg
    66901 ctccttatct ttgcagtaat tggcgtttta gtggccttga tagctcaatt ttactcagca
    66961 aaggcagcag taggttttgc taaggaattg acaaacgatc tttatcgtca tattctttcc
    67021 ttgcccaagg acagcagaga ccgtctgaca acatctagtt tggtcactcg cttgacttcg
    67081 gatacttacc agattcagac tggtatcaat caattcctgc gtctcttttt gcgagcgccc
    67141 attatcgttt ttggtgccat ttttatggct tatcgaatct caactgagtt gactttctgg
    67201 ttcttagtca tggttgccat tttgaccatt gtcattgtag ggttatctcg attggtcaat
    67261 cctctctaca gtagtctcag aaagaaaacg gaccaactgg ttcaggaaac gcgccagcaa
    67321 ttgcaaggga tgcgggttat tcgtgctttt ggtcaagaaa aacgagagtt acagattttt
    67381 caaaccctta accaagttta tgctagatta caagaaaaga caggtttctg gtctagttta
    67441 ttaacacctc tgacctatct gattgtcaat ggaactcttc tcgttattat ctggcaaggc
    67501 tatatttcaa ttcaaggagg agtgctcagt caaggtgctc tcattgctct tatcaattac
    67561 ctcttacaga ttttggtgga attggtcaag ctagccatgt tgataaattc tctcaaccag
    67621 tcctatatct cagccaagcg aatcgaggaa gtctttgttg aggctccaga ggatatccat
    67681 tcagagttag aacaaaagca agctaccaga gataaggttt tacaagtcca agaattgacc
    67741 tttacctatc ctgatgcggc ccagccttct ctgagataca tttcctttga tatgactcaa
    67801 ggacaaattc taggtatcat cgggggaact ggttctggta aatcaagctt ggtgcaactc
    67861 ttacttggac tttatccagt agacaagggg aacattgacc tttatcaaaa tggacgtagt
    67921 cctcttaatt tggagcagtg gcggtcttgg attgcctatg tacctcaaaa ggtcgaactc
    67981 tttaagggaa ctattcgttc caacttgact ttaggtttaa atcaagaagt gactgatcaa
    68041 gaactctggc aagccttgga aattgctcaa gctaaggatt ttgtcagtga taaggaagga
    68101 ctcttggatg ctctagttga agcaggaggt cgaaatttct caggtggaca aaaacaaagg
    68161 ttgtctatcg cccgagcagt cttgcgccaa gctccgtttc tcatcctaga tgatgcaacc
    68221 tcggcactgg ataccattac agagtccaag ctcttgaaag ctattagaga aaattttcca
    68281 aacacgagct taattttgat ctctcaacga acctcaactt tacagatggc ggaccagatt
    68341 ctcctcttgg aaaaaggtga gttgctagct gttggcaagc acgatgactt gatgaaatcc
    68401 agccaagtct atcgtgaaat caatgcatcc caacatggaa aggaggacta gaatgaaacg
    68461 acaaactgta aaccagacgc tcaaacgttt agccgtagat ttagcaaacc atcccttcct
    68521 ccttttccta gcctttctag gaactattgc ccaagttggc ttatcaattt acctacctat
    68581 tctgattggg caggtcattg accaagtcct agtggctggt tcatcaccag ttttttggca
    68641 gatttttctc cagatgctct tggtggtaat aggaaatact ctggtacaat gggccaatcc
    68701 tctcctctat aatcgtctaa tcttctctta taccagagat ttacgagagc gaatcatcca
    68761 taaactccat cggttaccga ttgcttttgc ggatcggcaa ggcaatggag agatggtcag
    68821 tcgtgtaacc acggatatcg aacagttggc agctggcttg accatgattt ttaaccaatt
    68881 tttcattggt gttttgatga ttttggttag tattctagcc atgctccaaa ttcatctcct
    68941 catgactctc ttagtcttgc tgttgacgcc actgtccatg gtgatttcac gctttattgc
    69001 caagagatcc tatcatctct tccagaagca aacagagacg agggggattc agacccagtt
    69061 gattgaagaa tcgcttagcc agcagactat aatccagtcc ttcaatgctc aaacagagtt
    69121 tatccaaaga ttgcgtgagg ctcatgacaa ctactcaggc tattctcagt cagccatctt
    69181 ttattcttca acggtcaatc cttcgactcg ctttgtaaat gcactcattt atgccctttt
    69241 agctggagta ggagcttatc gtatcatgat gggttcaacc ttgaccgtcg gtcgtttagt
    69301 gacttttttg aactatgttc agcaatacac caagcccttt aacgatattt cttcagtgct
    69361 agctgagttg caaagtgctc tggcttgcgt agagcgtatc tatggagtct tagatagccc
    69421 tgaagtagct gaaacaggta aggaagtctt gaccagtgac caagttaagg gagctatttc
    69481 ctttaaacat gtctcttttg gctaccatcc tgaaaaaatt ttgattaagg acttgtctat
    69541 cgatattcca gctggtagta aggtagccat cgttggtccg acaggtgctg gaaaatcaac
    69601 tcttatcaat ctccttatgc gtttttatcc cattagctcg ggagatatct tgctggatgg
    69661 gcaatccatt tatgattata cacgagtatc attgagacag cagtttggta tggtgcttca
    69721 agaaacctgg ctcacacaag ggaccattca tgataatatt gcctttggca atcctgaagc
    69781 cagtcgagag caagtaattg ctgctgccaa agcagctaat gcagactttt tcattcaaca
    69841 gttgccacag ggatacgata ccaagttgga aaatgctgga gaatctctct ctgtcggcca
    69901 agctcagctc ttgaccatag cccgagtctt tctggctatt ccaaagattc ttatcttaga
    69961 cgaggcaact tcttccattg atacacggac agaagtgctg gtacaggatg cctttgcaaa
    70021 actcatgaag ggccgcacaa gcttcatcat tgctcaccgt ttgtcaacca ttcaggatgc
    70081 ggatttaatt cttgtcttag tagatggtga tattgttgaa tatggtaacc atcaagaact
    70141 catggataga aagggtaagt attaccaaat gcaaaaagct gcggctttta gttctgaata
    70201 agccattctc ttttgaaagt ttatggacga aaaaagttgc cttcgagtga cttttttgtt
    70261 acaatagcta gaaaaattgt tcactgtaat actcaatgaa aatcaaagag caaactagga
    70321 agctagccgt aggttgctca aagcacagct ttgaggttgt agataagact gacgaagtca
    70381 gctcaaaaca ctgttttgag gttgcagata gaactgacga agtcagctca aaacactgtt
    70441 ttgaggttgc agatagaact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
    70501 gaactgacga agtcagtaac cacacctacg gcaaagtgaa tctgaagtgg tttgaagaga
    70561 gtacaacttg tcttttaaaa aaggagtcta taatgaaagt ctttcagcat gtaaatatcg
    70621 tgacttgtga tcaaaatttc catgtttatc ttgatggaat cttagcagtc aaggattctc
    70681 aaatcgtcta tgttggtcaa gataagccag catttttaga acaagctgag cagattatag
    70741 actatcaggg agcttggatt atgcctggtt tggtcaattg tcacacccat tctgcaatga
    70801 caggtctgag agggatccga gatgacagca atctccatga atggctcaat gactatatct
    70861 ggccagcaga atctgagttt actcccgaca tgactaccaa tgcggtcaaa gaagccctga
    70921 cagagatgct ccagtcagga acaacaacct ttaacgatat gtataatccc aatggtgtgg
    70981 atatccagca aatttatcag gtggtgaaaa cttccaagat gcgttgttat ttttctccga
    71041 ctctcttttc ttcagagaca gaaacaactg ctgagactat aagcagaact cgatccatca
    71101 tagacgaaat cttaaaatat aaaaatccaa atttcaaggt tatggtagca cctcattctc
    71161 cgtatagctg cagtagagac ttgctggaag cgagtttgga aatggcaaaa gagctaaata
    71221 ttccgctcca tgtccatgtg gcggagacca aggaggagtc aggaattatc ctcaaacgat
    71281 acggcaaacg cccccttgct tttcttgaag aactgggtta tttagatcat ccgtccgtat
    71341 ttgctcacgg ggtcgaatta aacgagagag aaattgaacg cttggcatct tctcaagtgg
    71401 ctatcgccca caatcctatc agtaacctca aactggcatc aggaattgct ccaattatcc
    71461 agctccaaaa agcgggagta gcagtcggaa ttgcgactga ctcggttgct tccaataaca
    71521 atctagatat gtttgaggaa ggaaggactg cagctcttct tcagaagatg aaaagtgggg
    71581 atgccagcca gtttccaatc gaaacagctc tcaaggtact gacaatcgaa ggggctaagg
    71641 cccttggaat ggaaaatcag ataggaagtc tggaagtcgg caagcaagca gattttctgg
    71701 tcattcaacc acaagggaaa attcatctcc aacctcagga aaatatgctg tctcacctgg
    71761 tttatgcagt taaatctagt gatgtagatg atgtttatat cgccggagaa caggttgtta
    71821 agcaaggtca agtcctgaca gtagaacttt aaaagaaaaa tcacgaaaaa ttttaaaaaa
    71881 agtttgcaaa aatcttgcat tctttttttg actatgctat acttatatac ggtttaaaaa
    71941 aactgcctaa gacagtaggg gagctcgact cataaatatc ctaccgagga caagacgtat
    72001 catgtaaaaa gaagcgtatt gtactttcgt gtctaggttt gggcgcgttt ttctttttga
    72061 aaaattcccc aagcaaaata attacggagg tgaacacact aatgagtgaa gcaattattg
    72121 ctaaaaaagc ggaactagtt gacgtagtag ctgaaaaaat gaaagctgct gcatctatcg
    72181 tcgttgtaga cgctcgtggt ttgacagttg agcaagatac agttcttcgt cgtgagcttc
    72241 gtggaagcga agttgagtat aaagttatta aaaactcaat cttgcgtcgt gcagctgaaa
    72301 aagctggtct tgaagatctt gcatctgtat ttgttggacc atctgcagta gcattttcta
    72361 atgaagatgt tatcgcacca gcgaaaatct tgaacaactt ttctaaaaac gctgaagcac
    72421 ttgaaattaa aggtggtgca atcgaaggcg ctgtcgcatc taaagaagag attcttgcac
    72481 ttgcaactct tccaaaccgc gaaggacttc tttctatgct cctttctgta cttcaagcgc
    72541 cagtgcgcaa cgttgctctt gcagtcaaag cggttgcaga aagcaaagaa gacgcggctt
    72601 aatcttaagc tacacagcgt agcctagcta cgaaaaaaac tattataaaa tttaaaactt
    72661 atttggagga aataacaatg gcattgaaca ttgaaaacat tattgctgaa attaaagaag
    72721 cttcaatcct tgaattgaac gaccttgtaa aagctatcga agaagaattt ggtgtaactg
    72781 cagctgctcc tgtagctgtt gctgcagctg atgcagctga tgctggtgct gctaaagatt
    72841 cattcgacgt tgaattgaca tctgcaggcg acaaaaaagt tggcgttatc aaagttgtac
    72901 gtgaaattac tggtcttggt cttaaagaag ctaaagaact tgttgacggt gcaccagcac
    72961 ttgttaaaga aggcgttgca actgcagaag ctgaagaaat caaagctaaa ttggaagaag
    73021 ctggagcttc agttactctt aaataagagg catataccaa ttagaattcg gaatactata
    73081 gtatcagcct tttagaatcg tgaacacatt ttagaaactg ataaatttat ttagtttcct
    73141 accaaaaacc ctaccaaaaa ttctttggca gggtttttct ttttaataaa ttttcggagg
    73201 tagacactag attgtctccc cctttttttg tgtttcggag gtaattatgc aaaaggaagg
    73261 acagtcatca cgtcaattcg tgaagagtca tctcatgact atcatgggag ttgatattgt
    73321 aaaagcaact cagttagttg atgaaatgga acaagtaggt ttaatccgat ttgatgaatt
    73381 tggaaatgtt ggaattttag tcttggaggg acaatcatga agcgtattac cgctagtcaa
    73441 tatcagacat cagagcgtta ttataagctc cccaaacttt tatttgagag tgaacggtat
    73501 aagaatatga aactggaggt taaggtggtt tactcagttt taaaagatcg gttggagttg
    73561 tctttgagca aagcttggat tgatgaggat ggggctattt atttgattta ttccaattca
    73621 aatttgatgg cacttttagg ctgttcaaag tcaaaattac tctccatgtg agtttgaggt
    73681 gacattttta gatgattacc ataaaaaaca taattaccca ctattttatg aatcctatct
    73741 tcaaaacgtt atggaattcc ttgaaagtca ggatataaag aacggagtta atgcctttgt
    73801 agatgataat cagaatcttg tttttgtttt atattgacaa gactatcgag ccgagggaaa
    73861 agaggggata cttacaaccc aagtaactgt aaaagcttat gatgaagaca agaaatcgat
    73921 taacttcgca aatttattag attccttaat cgtctcagaa tatcaaatgg aaccgaatct
    73981 ttgggaggtc tcccatgatt gatctctatc taagtaaaaa tagacaaaga aatcaacttc
    74041 ttttagattt cttccaaaac tatggcatag aggtatcttg tcattcagtt tctgaaatga
    74101 caaaggacaa attaattgag atgatgagct attcttcaga ttgttttgag tttttatctc
    74161 ccaatttatt acgatttaag aaccgtgaca atctaagatt aacggatttc gttgagataa
    74221 ttttaaaaaa tcctgaacta accatcagac ttcctcttgc ggtttcaaat aagcgagttt
    74281 atccaagtct gaatttggaa gaggctagag ctctattgcc aagagatacg aaacaattga
    74341 tttacatggc gcaaacacat tatttatcta actaaaggag aagcaatatg gctgaacgat
    74401 tttgggagaa cttgtccatt attttggctg aaagaaatat cagctgtatt gagttaacca
    74461 gaaaaatgtt tgcgggagag tttcactatc caagtgaatt gaatcgtttg tatcaaaaga
    74521 ttcgccacta gaagatggaa caacgaatgc ctcaaagttc atgggtagaa aggattgtgc
    74581 aggtattaga tttagattat gaagatttat ttcggaggta actatgaaaa gaataattcc
    74641 agtttatata ttccaacaag taaatgtcct attggtatct ctatacttat tgaaatttct
    74701 ttgtatcggt gagttaacta tactacaggt tctctatggt gcgtctcttt tttctttttt
    74761 atggatgtat ggtcaacgaa aacaagtggt caaggtcaat atgaaaacta ggatgaaatg
    74821 ccttggtatt ggactagcta gtctactgat tataagtcta tgttttagcc tgattcatgc
    74881 tcaaggaagc acgaatcaaa caaatttaat tggccttcaa catcaagttc cttggttttc
    74941 atttttattg ttcttaatca atgcgagtat ggttgaagaa tttctgtatc gtgaaatttt
    75001 atggaacttg gttagaaaat tagatattcg agttgctttg acaagtgttt tatttgcctt
    75061 agtacatcat ccaggaacca ttctagcttg gtgtctgtac gtttcacttg gaatgttttt
    75121 aggtatggtg cgctataaat ctgacttatg gggaagtatg gggttacatt tggtgtggaa
    75181 ctttttagtt tatagtttgc tgctttttta aaataggtga cctgatttat ctcataaatc
    75241 tgtagttttt atgggattct cttttaattt agaaataaaa tatattacct atataaaata
    75301 aagaaactag aaatattttt tcaatttttt tagaaataaa atattatata gaaattccga
    75361 aaagaaataa taaaaccaaa ataaaatatt actaaaatat tttaatatga acatattatt
    75421 agtgataaac gttcttacaa tacatataat tacgataaaa agaataaaaa ctattatatt
    75481 tttatgtttg ttgttctgtt atgaaacgaa agaaattgga aactagtttc taatttatga
    75541 aaaatattga aaaaaaaaaa aagtgttaaa ataaagaatg taaacgttta cttcaactaa
    75601 ggagctcata tgttactgca aaaagaacta attccaatga tagaagctaa cttaccaaat
    75661 atggcatatg ctgaaaaaga cattgctaaa ttcttcttaa aacagcaacc tctgaatgat
    75721 tattcatcta aagcattgtg cgaatacctt aatgtatcca aagcaacatt gactcgattt
    75781 gcgaaaaaat gtggttttaa aggttttaga caattcattt tcaaatacca agagatgatt
    75841 catgagaaag aaaagttggc attatataca gaggcaacag aaaaagtttt atccgactat
    75901 gaggaaatgt tgagaaaaac ttacacggtt cttgatgaag ttcaacttga gcgtattgct
    75961 gagatgatag aaactgctga gcgtgtatat ctctacggta aaggaagttc tgttcttgct
    76021 ttacaagaaa tgaagatgag atttatgcgt ctcggagtga ttggtgaagt attatcagac
    76081 gaggatatga ttttgtggag tagcttacta cttaatgaaa attgccttgt cattggagca
    76141 tccatttcag gtcaaactga tattgtacta gaaggtctac aaaaagctgc agataaaggc
    76201 gctaaaacag ttttaatgac tacaagaaaa tttgacgaag aagattgttt ctttgatgaa
    76261 ctattgttat tagcttcgac cgatcatctc tcgtatggca atcgcatatc acctcagttt
    76321 ccaatacttt taattacaga ctgcttattc tctaattatc tggaaagtcc agagagacaa
    76381 tattattaca atcaaactat tatccataag gaggaataat aaaatgagcc aaatttggac
    76441 taaagaaaaa tttataagcc aagttcaagg tggagtcatt gtttcttgtc aagctttacc
    76501 tggtgaagcc ctttataatg aagaatttag cttgatgcct tttatggcta aagcagcttt
    76561 agaggcagga gcagtgggca ttcgcgcaaa ttctgtgcgt gatattaaag caattcagaa
    76621 agtagtagat ttaccaataa ttggaattat caaaagggat tatccacctc aagaaccata
    76681 tattactgct acgatgaaag aagtagatga acttgtagaa tgcggaacaa cagtcattgc
    76741 atttgatgca actttaagac caagatatga tggcttagtt gtcagtgaat ttatcaaaaa
    76801 aataaaagaa aaatatccga atcaattgct gatggcggat gtaagtaatt tagatgaagg
    76861 tctctatgca tttaaatcag gcgttgattt tgttggtaca acattatcag gttacacaag
    76921 tacaagtgta caatcagatg agcctgattt tgaactaatg aaaaaattgg ctgattttaa
    76981 tattccggta attgccgaag gaaaaattca ttatccagaa caattaaaaa aagcttatag
    77041 tttaggtgtt accagtgtag tcattggtgg agcgattaca cgtccaaaag aaattgctca
    77101 gcgatttatt aatgtcatca aataaaaaac aatataaagg agaaatctga tgaaagattt
    77161 aactaaatac aaaggcgtta tccctgcatt ttatgcttgc tatgatgaaa atggtgaaat
    77221 tagccaagat cgtgtaaaat ctctggtaca atatttcatt gacaaaggtg taaaaggtat
    77281 ctatgtaaat ggttcttcag gtgaatgtat ttaccaaagt gtagaagatc gtaaacaaat
    77341 tattgaagct gttatggaag ttgctaaagg taaattaaca gttatcaacc atattgcatg
    77401 taataacacg aaagatagta tcgaattggc aaaacattca gaaagtgttg gagtcgatgc
    77461 tattgcagct atcccaccta tttatttcaa attgccagag tattcaatcg cagcatattg
    77521 gaatgcaatg agtgaagctg cgtcaaatac agattttatt atctataata ttccacaatt
    77581 ggcaggggtt gcgttgactg gtagtttgta tgcaacaatg cgtcaaaatc ctcgtgtgat
    77641 tggagttaaa aattcttcta tgcctgtaca agatattcaa atgtttgtag ctgcaggtgg
    77701 agaagattac attgtattca atggtccaga tgaacaatat cttggtggtc gcttgatggg
    77761 agcagaagct ggtattggtg gtacttatgg cgttatgcca gatttgttct tgaaattgga
    77821 aagtttgatt caagaacgag atttagatac agctaaaaaa cttcaatatg ctatcaatga
    77881 agttatctat aagatgatat caggtaaggc aaatatgtat gctgtagcaa aagaagtttt
    77941 gcgtctaaat gaaaaacttg atttaggttc tgttcgtcaa cctttagaag cattggcaga
    78001 aggtgacttg gaagttgcaa aacaagcagc agaacttatt caacaagcac gaaaagaatt
    78061 tttataataa ataaaatcaa tatggagata tgttatgggc acaacaggat ttacaataat
    78121 tgacttaatt atcttgattg tttatttact tgcggtgttg gttgcaggta tctatttctc
    78181 taaaaaagag atgaaaggaa aagagttctt taaaggagat ggttcggttc cttggtatgt
    78241 tacttcggta tccatttttg ccacaatgct cagtccgatt tccttcttgg gactcgctgg
    78301 tagctcttat gcaggtagct ggattttatg gtttgctcaa ttagggatgg tagtagctat
    78361 tccactgaca attcgtttta tcttacctat ctttgcacgg atagacatcg atacggcata
    78421 tgattacttg gataaacgtt ttaattctaa agcacttcgt attatttcag cactcttgtt
    78481 tattatttat caattgggac gtatgtctat cattatgtac ctcccatcag ctggtttatc
    78541 agtattgaca ggaattgaca tcaatatttt gattattttg atgggtgtag ttgcaattgt
    78601 ttattcttat actggtggtc taaaatccgt attatggaca gactttattc aaggtgtgat
    78661 tctgattagt ggtgtcgttt tagctttatt tgtactgatt gctaatatta aaggtggctt
    78721 tggtgcagta gcagaaacat tagcaaacgg gaaattcctt gctgcaaatg aaaaactttt
    78781 cgatcctaac ttgctttcaa actccatctt tttaattgtg atgggttcag gctttacaat
    78841 cttgtcttcc tatgcttcat ctcaagattt ggttcaacgt tttactacaa cacaaaatat
    78901 taagaaactt aataagatgt tgttcacaaa cggtgttttg tcacttgcaa ctgcaacagt
    78961 cttttacttg attggtacag gcttgtacgt attctatcaa gtacaaaatg cagatagtgc
    79021 agctagcaat atccctcaag accaaatctt tatgtacttt attgcatacc agttaccagt
    79081 aggtatcaca ggtttgatct tggcagcgat ttatgcagca tctcaatcaa ctatttcaac
    79141 aggtttgaac tctgttgcaa cttcatggac attggatatt caagatgtca tttctaaaaa
    79201 tatgtcagac aatcgtcgta cgaaaattgc acaattcgta tctctagcag taggtttatt
    79261 ctcaattggt gtttccattg tcatggctca ctcagatatt aaatctgcat acgaatggtt
    79321 caatagtttc atgggacttg tacttggtct acttggtggt gtatttattc ttggatttgt
    79381 ttctaaaaaa gcaaataaac aaggtgctta tgcagcgctg attgtatcaa ccatcgtcat
    79441 ggtatttatt aaatacttcc ttcctccaac agctgttagc tactgggcat attcattgat
    79501 ttcaatctct gtatcagtag tttcaggtta tattgtatct gttcttactg gaaataaagt
    79561 atctgcacct aaatatacaa cgattcatga tattacagaa attaaagcgg attcaagttg
    79621 ggaagttcgt cactaataga aaagagaaaa taatatgatt atttctgaac aatctgattt
    79681 taaacgatat gcttctgtca ataaatattt ttcaaaagtc tgtgattttt tagaaaatac
    79741 aaatttgaca gatttagttg atggaaaaat tgatattgac ggggaaaatg tttttgcaaa
    79801 ttgtatgact tatctagctg atggagttcc aggagatatt tttgaaactc ataagaaata
    79861 tttagatatt catattgttg ttgaaaatac tgaaaaaatg gcagtaactt ccccagttcg
    79921 tgcccagtca cgtgtacctt ttagcgaaga gaaggatatt gctttttacg atagcaaaga
    79981 ctatcaaatt gttgaattgc ttccagggaa tatgttggtg acttttgaag aagatcttca
    80041 ccaaccaaag attcattgca atgatgaaac tgttaaaaaa cttgttatca aagttttaaa
    80101 cgaggaaaaa taaaatgaaa aaaaatatta aacaatatgt aaccttaggt actgtagtgg
    80161 tattatcagc atttgttgct aactcagttg cagctcagga gactgaaact tctgaagtat
    80221 caacaccaaa gttggtgcaa cctgttgcac caacgactcc gatttcggaa gtacaaccta
    80281 catcggataa ctcttcggaa gttactgtac aacctcgaac agttgaaact actgttaagg
    80341 atccatcttc tacagcggaa gaaactcctg tcttagaaaa aaataatgtt actttaacag
    80401 ggggcggaga aaatgttact aaagagttaa aggataaatt tactagcggt gactttactg
    80461 tagtgattaa gtacaatcag tcaagtgaga aaggcttaca agctctgttt ggaatatcta
    80521 attccaaacc cggtcaacaa aatagttatg tagatgtgtt ccttagagac aatggtgagt
    80581 tggggatgga agcgcgtgat acttcttcca ataaaaataa cctagtatcc agacctgctt
    80641 cagtttgggg taagtacaaa caagaggctg tgactaacac tgttgcagta gtagcagatt
    80701 cagtcaaaaa aacatattct ttatacgcaa atggtacaaa agtagtagaa aagaaagtgg
    80761 ataatttcct aaacatcaag gatattaaag gtattgatta ctatatgctt gggggagtga
    80821 aacgtgcagg aaaaacggcg tttggtttta acggaacact agaaaatatc aaattcttta
    80881 atagtgcatt ggatgaagaa actgttaaaa agatgacaac aaacgctgtt actggacatt
    80941 taatttatac ggctaatgat acaacaggtt ctaactattt ccgtattcca gttctgtata
    81001 cttttagcaa tggtcgggta ttttcaagca ttgacgctcg ttacggtgga actcatgatt
    81061 tcttgaataa aattaatatt gctacaagtt atagtgatga taatggtaag acatggacta
    81121 aaccaaaatt aacattggca ttcgatgatt ttgcgccagt accattagaa tggcctcgtg
    81181 aagttggtgg acgtgactta caaatcagcg gtggtgcaac ctatattgac tctgttattg
    81241 ttgaaaaaaa gaacaaacaa gtactcatgt ttgctgatgt gatgcctgct ggagtaagtt
    81301 ttagagaagc aactagaaaa gattcaggtt ataaacaaat tgatggtaat tattacctta
    81361 aattaaggaa acaaggtgat actgattaca attatactat tcgtgagaat ggtactgtat
    81421 acgacgatcg taccaacaga ccaactgaat tttcagtaga taaaaatttc ggtattaaac
    81481 aaaatggtaa ttatttgacg gtagagcaat attcggtttc atttgaaaat aataaaaaga
    81541 ctgaatatcg taatgggact aaagtccata tgaatatctt ctacaaagat gcattgttta
    81601 aagtagtgcc aacgaactat attgcatata tttctagcaa tgatcatggc gaatcttggt
    81661 ctgcaccaac tttattacct cctataatgg gacttaatcg gaatgcgcca tatttaggtc
    81721 ctggacgtgg aatcattgaa agctcaactg gacgtattct tattccgtct tacactggta
    81781 aagagtctgc gttcatttat agtgacgata atggagcatc ttggaaagtt aaagtagtgc
    81841 cacttccttc tagttggtca gcagaagcac aatttgtaga attgagtcca ggagtaattc
    81901 aagcatatat gcgtacaaat aatggtaaaa ttgcatattt aacaagtaaa gacgcaggta
    81961 ctacttggag tgcaccggaa tatttgaaat ttgtttcaaa tccaagttat ggaacacaat
    82021 tatcaatcat caattatagc caattgattg atggtaaaaa ggctgtcatt ttaagtactc
    82081 caaactccac aaatggtcgt aaacacggac aaatttggat tggtctaatt aatgatgata
    82141 atacaattga ttggcgttat catcacgacg ttgattatag taactatgga tactcatatt
    82201 caacattgac agagttacca aatcatgaaa ttggattgat gtttgaaaaa tttgattcat
    82261 ggtctcgtaa tgaacttcat atgaaaaatg ttgtaccata tataacattt aagattgaag
    82321 atctgaaaaa gaattaaagc tgaaatttga aaatatataa aaagaggata aaaattatgg
    82381 taaattacgg tattgttgga gctggatatt ttggagctga tttagctcgc tcaatgaaca
    82441 aaattgaaga tgcaaaagtg gttgcggtat ttgacccaaa tcatggagaa gaagttgctc
    82501 aagagttggg atcagatgtt tgtgcaagtt tagatgaact tgtagcacgt gaagatattg
    82561 attgtgtgat cgtagcttca cctagctacc ttcaccgtga accagttgtg aaagctgctc
    82621 aacatggcaa acacgtattt tgtgaaaagc caattgcatt gtcttatgaa gattgtaaag
    82681 ccatggttga cgcatgtaaa gaaaataatg tcatctttat ggctggtcac atcatgaact
    82741 tctttaacgg tgtacaccat gctaaagaat tgattactca aggtaaaatc ggtaaagttc
    82801 tttattgcca tgctgctcgt acaggttggg aagaacaaca accaactgta tcatggaaga
    82861 aacttcgttc tcaatctgga ggacatttgt accaccatat tcatgaatta gattgcattc
    82921 agtttatcat gggaggactt cctgaaaaag cgacaatggt aggaggcaat gtatatcata
    82981 aaggtgaaaa ctttggtgat gaagatgata tgctcattgt aaacttagaa tactctgatg
    83041 atcgttatgc tgttttggaa tatggtaatg ctttccgttg gggtgaacac tacgtcttga
    83101 ttcaaggaac tgaaggagct atcaaacttg acttgttcaa tactggcggt actcttcgtg
    83161 ttaaaggtga aggagaatca cacttcttag ttcatgaaac tcaagaggaa gatgatgatc
    83221 gtacagctat ctataccggt cgtggtatgg atggagcaat tgcgtacggt aaaccaggag
    83281 tacgttgccc attatggttg caaacatgta ttgataaaga aatggaatat ctacatgaca
    83341 tcattaaagg tggagaaatt acagaagaat ttgaaaaact tctcaatggt gtagctgctt
    83401 tagaatcaat cgctaccgct gatgcatgta ctttatcagt taaagaagat cgaaaagtaa
    83461 gtctttcaga aatcacaaat gcttaacttt tgtaaaacag aatagtaaat tcttgtcatt
    83521 atataatttc taaagttctg tgatacaact cattgaataa agaaatagag atgggactgg
    83581 gataatgccc agtcccattt tttatcaaaa agtaatgaga tcaaaaatgt gggagtgttg
    83641 aaatgaagat tataggtatc gatattggcg gaacaacaat taaggcagat ttatacgatg
    83701 agtttggaac gagtttgaat catttcaaag agatagaaac aattattgac tatgatttgg
    83761 gaacgaatca gatattaaat caggtctgtg atttaattgg tgagtatact ttaaatcatt
    83821 caattgatgg tgttgggatt tccactgctg gagttgttaa tgctaatact ggagaaatca
    83881 tctatgcagg ctatacaata ccagggtata tcggagtaaa ctttactgcc gaaatagaaa
    83941 aacgttttgg gttgtatact tttgttgaaa atgatgttaa ttgtgctgca ttaggtgaat
    84001 tgtggaaggg acaagccaaa gataagaaaa atgtagtaat ggttactatt ggaacaggta
    84061 taggaggcag tattattgtc aacggacaaa ttgttaacgg atttaactat actgctggtg
    84121 aagtaggtta tattcctgta ggtaattcgg attggcaaag taaagcctca acaaccgcat
    84181 tgattcattt atatcaaaaa aagagcttga aaactaatca aactggacgt actttcttca
    84241 ctgatttaag atctggagat aaagttgctg aagaaacttt tgaaattttt gtagaaaatc
    84301 taacaaaagg tttattaacg atttcttatc tacttaatcc agaaattctc atattaggag
    84361 gtgggattct ggatagtaag gatattttgt tacctgaaat tcaaagttct ttagctaaaa
    84421 atgcaatgga taataggttt ttacctaaaa atcttgtggc agctacatta ggaaatgaag
    84481 ctggtcgtat aggagctgta aaaaatttct tagatagaat ttctaataaa tagtatgtaa
    84541 gataaggagg tgtcacaatg actaactctg tattttcgac aatgcaagat attgagaatg
    84601 ttgcaaccga tattataaaa tcatatgata atgagattta tacttataaa gctgtttccc
    84661 aagaagaatt ggaaaaacta gaaaaaagtt atgatgaaaa aagtcacgaa gaattagttt
    84721 caatagaaag caatttagaa atgaaacaac agaaccttat tgatgaggtt aataaaacaa
    84781 tcaaggaaaa tgatgcaaat attcagtata tttcatcaag taggagagga gaatttgtag
    84841 aaaaaattat tggtagggtg gtagaaaaat atggccatta gtcagatgaa aagaatctct
    84901 ctactatttt ctaaaagtag tcttgatgat gttttaaaaa ctattcaaga actagagtca
    84961 gtgcagttcc gtgatttaaa ggttcaggat aactggtcag aagctctaga aaaagatgaa
    85021 gttgtatttc caactattca aatttttcat acttctaatt ccaatcatgg ggttattgag
    85081 ggaaatgatg ccttgactta tttgatgaat caacaacaac atttagaagc aactgtagag
    85141 aaattacaag aatacctacc gaaagaaaac acgtttaaat tattgcagca acctccgata
    85201 actacctctt atgaagaatt agagaaattt ggtaaagcta atgttgctga gggtgttctt
    85261 aaaaaagtga atcatcaaat taacagagtt catgaattag aaagacacat tcaaagtaat
    85321 aatgaggaaa tagagcgatt aataaagtgg gaaaaattag aaattgttcc tgcgaattta
    85381 gaacaatttt ctttctgtaa aggaaaagtc ggaacaattc caaggactga agataatcgc
    85441 ttatacaata gtcttttaga aaacaatatt gaagttcaag aaatattttc taatgataga
    85501 gagtacggtg ttgttgtttt ctatcagtct agttactcta tagattttga tgaatactta
    85561 tttgaaccat ttgattattc tagaaaggaa ttaccgaagc agcgagtagt agatttagat
    85621 caagaaaaca tgcagttaat aactgaaaaa gagaatatta tcgcatcgtt gcaagattca
    85681 aagaaatatt tgatagattt acaatggcaa atagactata ttttatctat ctatgctcgt
    85741 caaatctcta agaataactt tttgtgcact ccgcatctag ttgcattaga aggatggata
    85801 gaagaaactc gtattttata ttttataaaa gttatggatg agcattttgg acattctatt
    85861 tatatttatg aatcggaaac attgacggat aatcaagatg aaatacctat caaattaacg
    85921 aatcattctt taattgaacc atttgaatta ttgacagaaa tgtatgctct gcccaaatat
    85981 tatgagaaag atcctacacc tgtattagca ccattttact ttacattttt tggaatgatg
    86041 gttgctgatt taggctatgg tttactattg tttttaggaa caatgttagc attaaaaatt
    86101 tttcatctac cttcagcaac taagagattt ttaaaattct ttaatatatt aggggtagcc
    86161 gttgcaattt ggggtggaat ctatggctca ttttttggat atgagttgcc atttcatctg
    86221 atatctacaa cctctgatgt catgactata ttagtagtgt cagttgtgtt tgggtttatt
    86281 acagtatttg caggtttgtt agcttcagga ctacaaaaag taagaatgaa gaaatatgca
    86341 gaagcatata attcaggatt tgcgtggtgt gttattctgc ttggcttgtt atttattgct
    86401 gttggaatgt tgatgcctga tatgagaccg ttatttgtat tagggaaatg ggtatctatt
    86461 tttaatgctg tggggatttt gattgtttct attattcaaa ccaaaagctt gtcaggtatt
    86521 ggagcaggat tgtttaatct atataacatt tcatcttata taggtgattt agttagtttc
    86581 actcgattga tggcattagg attatctgga gcaagtatag catcagcttt caatttaatt
    86641 gttggtttgt ttccgggaat attggctaaa ctgacaattg gattagtatt attcattctt
    86701 ttacatgcga tcaatatttt tctatcgtta ctatcaggat atgttcatgg agcacgtctg
    86761 atatttgttg aattttttgg taagttttat gagggtggag gaaaaccatt tcaacctttg
    86821 aaggcttctg agaaatatat taaggttatt acaaagaatt aatggaggat atatataatg
    86881 gaacatttag caacttattt ttcaacctat ggaggagctt tcttcgctgc attgggaatt
    86941 gtattggcgg ttggattaag cggtatgggg tctgcttatg gagttggtaa ggctgggcaa
    87001 tctgccgcag ctttactgaa agaacagcct gaaaagtttg cctcagcttt gatattgcaa
    87061 ttattgcccg gaacacaagg attatatggt tttgttattg gaattttaat ttggttgcaa
    87121 ttaactccag aacttccttt agaaaaaggc gttgcttatt tctttgtagc tcttccaatt
    87181 gctattgtag gatacttttc agctaagcat caaggaaatg tagcagtagc gggaatgcaa
    87241 atcttggcta aaagaccaaa agaattcatg aagggagcaa ttttagctgc catggtagaa
    87301 acctatgcaa ttcttgcttt tgtcgtatca ttcattttga cccttcgtgt ataagaaata
    87361 aatttgcaat tcaaaggagg tgtctaaatg agcaatttag aaaacttacg agagtctgtt
    87421 attgaacaag ctcatgaaaa agggcgtatg aaattattgg attccaaaaa gaagattgat
    87481 gatgaatttg aaatgcaaaa gtcgctcatt ataaagaaaa aagaagctga acatgaacga
    87541 aagttaaaag aattgcaaca gaaatatcaa ataatttttc aacaattaaa aaataaggaa
    87601 cgccaatcaa cgttagtatc aaaacagaaa atattaaaag aactttttca atctgcttta
    87661 ctagaaatgg aatcttggag tgcagataaa gaaatggagt tcatctatcg aattctggaa
    87721 cgatattcac aacaagaggt catagtaacc tttggggaac ggactttagc taaattcaat
    87781 ttggaacaat tagagaaatt gaaattctct tttccaaatt atttatttag tgaacaacct
    87841 atctcaaatg aatcaggctt acttatttca ataggtaaaa ttgatgataa ctatttgtat
    87901 aaaacattaa ttggatcgat ttctaaggaa gaaagttcaa gtatcgcaaa tc
//
LOCUS       DAVLHB010000002        86181 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLHB010000002 DAVLHB010000000
VERSION     DAVLHB010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 86181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.002"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            85..3435
                     /locus_tag="VXE36_000093"
     CDS             85..3435
                     /locus_tag="VXE36_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0778474.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMINLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3941..4411)
                     /locus_tag="VXE36_000094"
     CDS             complement(3941..4411)
                     /locus_tag="VXE36_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0778475.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4428..6701)
                     /locus_tag="VXE36_000095"
     CDS             complement(4428..6701)
                     /locus_tag="VXE36_000095"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0778476.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7048..10149
                     /locus_tag="VXE36_000096"
     CDS             7048..10149
                     /locus_tag="VXE36_000096"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0778477.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLDITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVELLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10232..11239
                     /gene="pfkA"
                     /locus_tag="VXE36_000097"
     CDS             10232..11239
                     /gene="pfkA"
                     /locus_tag="VXE36_000097"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0778478.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11298..12803
                     /gene="pyk"
                     /locus_tag="VXE36_000098"
     CDS             11298..12803
                     /gene="pyk"
                     /locus_tag="VXE36_000098"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0778479.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(13547..13772)
                     /locus_tag="VXE36_000099"
                     /pseudo
     CDS             complement(13547..13772)
                     /locus_tag="VXE36_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            14620..15492
                     /locus_tag="VXE36_000100"
     CDS             14620..15492
                     /locus_tag="VXE36_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0778480.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFNSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(15638..15982)
                     /locus_tag="VXE36_000101"
                     /pseudo
     CDS             complement(15638..15982)
                     /locus_tag="VXE36_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16125..16436
                     /locus_tag="VXE36_000102"
     CDS             16125..16436
                     /locus_tag="VXE36_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778481.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            16440..17156
                     /locus_tag="VXE36_000103"
     CDS             16440..17156
                     /locus_tag="VXE36_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0778482.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYSASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(17286..18101)
                     /locus_tag="VXE36_000104"
     CDS             complement(17286..18101)
                     /locus_tag="VXE36_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0778483.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLIIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(18098..19003)
                     /locus_tag="VXE36_000105"
     CDS             complement(18098..19003)
                     /locus_tag="VXE36_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0778484.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGWAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            19415..21544
                     /locus_tag="VXE36_000106"
     CDS             19415..21544
                     /locus_tag="VXE36_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0778485.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTD
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRISESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            21531..21980
                     /locus_tag="VXE36_000107"
     CDS             21531..21980
                     /locus_tag="VXE36_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0778486.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            22038..22310
                     /locus_tag="VXE36_000108"
     CDS             22038..22310
                     /locus_tag="VXE36_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0778487.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(22358..22522)
                     /locus_tag="VXE36_000109"
     CDS             complement(22358..22522)
                     /locus_tag="VXE36_000109"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778488.1"
                     /translation="MDEAGEILLILFKNQSANYINFTLPTKLQPAAGFLVCTLIFIEY
                     KSKKALNQAV"
     gene            complement(22664..22855)
                     /locus_tag="VXE36_000110"
     CDS             complement(22664..22855)
                     /locus_tag="VXE36_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778489.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            23283..24041
                     /locus_tag="VXE36_000111"
     CDS             23283..24041
                     /locus_tag="VXE36_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778490.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            24043..26031
                     /locus_tag="VXE36_000112"
     CDS             24043..26031
                     /locus_tag="VXE36_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778491.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTIHKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(26073..26717)
                     /locus_tag="VXE36_000113"
     CDS             complement(26073..26717)
                     /locus_tag="VXE36_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0778492.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(26743..27738)
                     /locus_tag="VXE36_000114"
     CDS             complement(26743..27738)
                     /locus_tag="VXE36_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0778493.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            28445..29920
                     /locus_tag="VXE36_000115"
     CDS             28445..29920
                     /locus_tag="VXE36_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0778494.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(29886..30601)
                     /locus_tag="VXE36_000116"
                     /pseudo
     CDS             complement(29886..30601)
                     /locus_tag="VXE36_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            30688..30825
                     /locus_tag="VXE36_000117"
     CDS             30688..30825
                     /locus_tag="VXE36_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778495.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            30856..31716
                     /gene="speE"
                     /locus_tag="VXE36_000118"
     CDS             30856..31716
                     /gene="speE"
                     /locus_tag="VXE36_000118"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0778496.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            31713..32972
                     /locus_tag="VXE36_000119"
     CDS             31713..32972
                     /locus_tag="VXE36_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0778497.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            32972..34099
                     /gene="nspC"
                     /locus_tag="VXE36_000120"
     CDS             32972..34099
                     /gene="nspC"
                     /locus_tag="VXE36_000120"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0778498.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            34096..35181
                     /gene="aguA"
                     /locus_tag="VXE36_000121"
     CDS             34096..35181
                     /gene="aguA"
                     /locus_tag="VXE36_000121"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0778499.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            35191..36066
                     /gene="aguB"
                     /locus_tag="VXE36_000122"
     CDS             35191..36066
                     /gene="aguB"
                     /locus_tag="VXE36_000122"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0778500.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTDIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(36247..37056)
                     /locus_tag="VXE36_000123"
     CDS             complement(36247..37056)
                     /locus_tag="VXE36_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0778501.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            37328..37549
                     /locus_tag="VXE36_000124"
     CDS             37328..37549
                     /locus_tag="VXE36_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778502.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            37603..38274
                     /locus_tag="VXE36_000125"
     CDS             37603..38274
                     /locus_tag="VXE36_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0778503.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(38326..38523)
                     /locus_tag="VXE36_000126"
     CDS             complement(38326..38523)
                     /locus_tag="VXE36_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0778504.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFLRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            38516..39424
                     /locus_tag="VXE36_000127"
     CDS             38516..39424
                     /locus_tag="VXE36_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0778505.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            39421..39882
                     /locus_tag="VXE36_000128"
     CDS             39421..39882
                     /locus_tag="VXE36_000128"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0778506.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            39872..40759
                     /locus_tag="VXE36_000129"
     CDS             39872..40759
                     /locus_tag="VXE36_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0778507.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            40762..42645
                     /gene="cbpE"
                     /locus_tag="VXE36_000130"
                     /gene_synonym="pce"
     CDS             40762..42645
                     /gene="cbpE"
                     /locus_tag="VXE36_000130"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0778508.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNFERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIVGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            42725..43855
                     /locus_tag="VXE36_000131"
     CDS             42725..43855
                     /locus_tag="VXE36_000131"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0778509.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            43865..45127
                     /locus_tag="VXE36_000132"
     CDS             43865..45127
                     /locus_tag="VXE36_000132"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0778510.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            45131..45928
                     /gene="proC"
                     /locus_tag="VXE36_000133"
     CDS             45131..45928
                     /gene="proC"
                     /locus_tag="VXE36_000133"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0778511.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLILEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            46148..46786
                     /locus_tag="VXE36_000134"
     CDS             46148..46786
                     /locus_tag="VXE36_000134"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0778512.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            46783..47673
                     /locus_tag="VXE36_000135"
     CDS             46783..47673
                     /locus_tag="VXE36_000135"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0778513.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            47713..48030
                     /gene="yabA"
                     /locus_tag="VXE36_000136"
     CDS             47713..48030
                     /gene="yabA"
                     /locus_tag="VXE36_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0778514.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            48033..48902
                     /gene="rsmI"
                     /locus_tag="VXE36_000137"
     CDS             48033..48902
                     /gene="rsmI"
                     /locus_tag="VXE36_000137"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0778515.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            49129..49647
                     /locus_tag="VXE36_000138"
     CDS             49129..49647
                     /locus_tag="VXE36_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0778516.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            49756..50403
                     /locus_tag="VXE36_000139"
     CDS             49756..50403
                     /locus_tag="VXE36_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV0778517.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKIES"
     gene            complement(50356..51197)
                     /locus_tag="VXE36_000140"
     CDS             complement(join(50356..50826,50829..51197))
                     /locus_tag="VXE36_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0778518.1"
                     /translation="MNDEASKQLTDARFKRFVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKFHAMKTQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTVEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYQNHRKRFGLRMNLIAGIINHELGFYFCRKSNVI
                     LKL"
     gene            51192..51446
                     /locus_tag="VXE36_000141"
     CDS             51192..51446
                     /locus_tag="VXE36_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0778519.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            51691..53025
                     /gene="trmFO"
                     /locus_tag="VXE36_000142"
     CDS             51691..53025
                     /gene="trmFO"
                     /locus_tag="VXE36_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0778520.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            53109..53846
                     /locus_tag="VXE36_000143"
     CDS             53109..53846
                     /locus_tag="VXE36_000143"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0778521.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            53855..54412
                     /gene="frr"
                     /locus_tag="VXE36_000144"
     CDS             53855..54412
                     /gene="frr"
                     /locus_tag="VXE36_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0778522.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            54472..55326
                     /gene="cvfB"
                     /locus_tag="VXE36_000145"
     CDS             54472..55326
                     /gene="cvfB"
                     /locus_tag="VXE36_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0778523.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            55335..55550
                     /locus_tag="VXE36_000146"
     CDS             55335..55550
                     /locus_tag="VXE36_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0778524.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            55636..56604
                     /locus_tag="VXE36_000147"
     CDS             55636..56604
                     /locus_tag="VXE36_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0778525.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(56582..56761)
                     /locus_tag="VXE36_000148"
     CDS             complement(56582..56761)
                     /locus_tag="VXE36_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778526.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            56797..57297
                     /locus_tag="VXE36_000149"
     CDS             56797..57297
                     /locus_tag="VXE36_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778527.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            57300..57559
                     /locus_tag="VXE36_000150"
                     /pseudo
     CDS             57300..57559
                     /locus_tag="VXE36_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(57926..58252)
                     /locus_tag="VXE36_000151"
     CDS             complement(57926..58252)
                     /locus_tag="VXE36_000151"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778528.1"
                     /translation="MVDVAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(58198..58611)
                     /locus_tag="VXE36_000152"
     CDS             complement(58198..58611)
                     /locus_tag="VXE36_000152"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0778529.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(58612..59037)
                     /locus_tag="VXE36_000153"
     CDS             complement(58612..59037)
                     /locus_tag="VXE36_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0778530.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            59214..59783
                     /locus_tag="VXE36_000154"
     CDS             59214..59783
                     /locus_tag="VXE36_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778531.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            59851..60501
                     /locus_tag="VXE36_000155"
     CDS             59851..60501
                     /locus_tag="VXE36_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0778532.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            60485..62725
                     /locus_tag="VXE36_000156"
     CDS             60485..62725
                     /locus_tag="VXE36_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0778533.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            62904..63092
                     /locus_tag="VXE36_000157"
     CDS             62904..63092
                     /locus_tag="VXE36_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778534.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            63124..63711
                     /locus_tag="VXE36_000158"
     CDS             63124..63711
                     /locus_tag="VXE36_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778535.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            63715..64896
                     /locus_tag="VXE36_000159"
     CDS             63715..64896
                     /locus_tag="VXE36_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778536.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIILLLVGILFIESWGSLRKKEVFK
                     V"
     misc_feature    65056..65187
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            65203..65733
                     /gene="infC"
                     /locus_tag="VXE36_000160"
     CDS             65203..65733
                     /gene="infC"
                     /locus_tag="VXE36_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0778537.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            65766..65966
                     /gene="rpmI"
                     /locus_tag="VXE36_000161"
     CDS             65766..65966
                     /gene="rpmI"
                     /locus_tag="VXE36_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0778538.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            66018..66377
                     /gene="rplT"
                     /locus_tag="VXE36_000162"
     CDS             66018..66377
                     /gene="rplT"
                     /locus_tag="VXE36_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0778539.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            66435..66815
                     /locus_tag="VXE36_000163"
     CDS             66435..66815
                     /locus_tag="VXE36_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0778540.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            67065..67865
                     /locus_tag="VXE36_000164"
     CDS             67065..67865
                     /locus_tag="VXE36_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0778541.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            67828..68814
                     /locus_tag="VXE36_000165"
     CDS             67828..68814
                     /locus_tag="VXE36_000165"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0778542.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            68856..71021
                     /gene="lytB"
                     /locus_tag="VXE36_000166"
     CDS             68856..71021
                     /gene="lytB"
                     /locus_tag="VXE36_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0778543.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWIFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWIYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLYFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(71082..72737)
                     /gene="pavA"
                     /locus_tag="VXE36_000167"
     CDS             complement(71082..72737)
                     /gene="pavA"
                     /locus_tag="VXE36_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0778544.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            72842..73339
                     /gene="ybeY"
                     /locus_tag="VXE36_000168"
     CDS             72842..73339
                     /gene="ybeY"
                     /locus_tag="VXE36_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0778545.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            73320..73715
                     /locus_tag="VXE36_000169"
     CDS             73320..73715
                     /locus_tag="VXE36_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0778546.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            73732..74631
                     /gene="era"
                     /locus_tag="VXE36_000170"
     CDS             73732..74631
                     /gene="era"
                     /locus_tag="VXE36_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0778547.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            74679..75503
                     /gene="mutM"
                     /locus_tag="VXE36_000171"
     CDS             74679..75503
                     /gene="mutM"
                     /locus_tag="VXE36_000171"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0778548.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVTGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLNQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            75503..76108
                     /locus_tag="VXE36_000172"
     CDS             75503..76108
                     /locus_tag="VXE36_000172"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0778549.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            76095..77294
                     /locus_tag="VXE36_000173"
     CDS             76095..77294
                     /locus_tag="VXE36_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0778550.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNAILSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            77294..77443
                     /gene="rpmG"
                     /locus_tag="VXE36_000174"
     CDS             77294..77443
                     /gene="rpmG"
                     /locus_tag="VXE36_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0778551.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLEFK"
     gene            77483..77716
                     /gene="secG"
                     /locus_tag="VXE36_000175"
     CDS             77483..77716
                     /gene="secG"
                     /locus_tag="VXE36_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0778552.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            77818..80172
                     /gene="rnr"
                     /locus_tag="VXE36_000176"
     CDS             77818..80172
                     /gene="rnr"
                     /locus_tag="VXE36_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0778553.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPETVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            80135..80602
                     /gene="smpB"
                     /locus_tag="VXE36_000177"
     CDS             80135..80602
                     /gene="smpB"
                     /locus_tag="VXE36_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0778554.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            80618..81478
                     /gene="tehB"
                     /locus_tag="VXE36_000178"
     CDS             80618..81478
                     /gene="tehB"
                     /locus_tag="VXE36_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0778555.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            81551..82504
                     /gene="coiA"
                     /locus_tag="VXE36_000179"
     CDS             81551..82504
                     /gene="coiA"
                     /locus_tag="VXE36_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0778556.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQYFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            82523..84325
                     /gene="pepF"
                     /locus_tag="VXE36_000180"
     CDS             82523..84325
                     /gene="pepF"
                     /locus_tag="VXE36_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0778557.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLKGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            84327..85040
                     /locus_tag="VXE36_000181"
     CDS             84327..85040
                     /locus_tag="VXE36_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0778558.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            85107..86048
                     /gene="prsA"
                     /locus_tag="VXE36_000182"
     CDS             85107..86048
                     /gene="prsA"
                     /locus_tag="VXE36_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0778559.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
BASE COUNT        26075 a        15664 c        19118 g        25324 t
ORIGIN      
        1 ttgtgagata gctataaaag tgtggagaaa tagcttgaaa tttagtataa tatagctaaa
       61 ctatttgttt aaagtgagaa aaaaatggga aattttagct ttcttttaaa aaatgacgaa
      121 tatgaatctt tttcaaaacc ttgcattgaa gctgaaaata tgattgctac atcaactgtg
      181 gctactgcct ttatggcgcg tcgtgctttg gagcaggctg tccattggat atatagtcac
      241 gattcatatt tagaagctcc ctatcgtgct actctatctt ctttagtatg ggatgatgat
      301 tttagggata tcgtagattc tgaactccac aagcagatag ttctgttgat tcggtgggga
      361 aaccatgctg ctcatggtgg tgaaattaag gaacgagaag cgattttagc tttacatcat
      421 ttgtatcagt ttgttaattt tatcgattat tgttacagca atgaatttgt ggagcgttat
      481 tttgatgaga agtgcttacc actttcagca aacatcaaat accgagaaac tccacaatct
      541 atgataaact tacaagacag tttaccagaa ctgcctgatt ttcatgaaca gatggctgct
      601 cagtccgtag aagttcaaga gacttatact gaaaaacgtg agactgcagc gcaacggcaa
      661 gatgtgcctt tccatattga tcaattatct gaggcagaga caagaaagct ctttattgat
      721 atcgatctcc gtttagcagg atggatattt gaagaaaact gtcgtgttga gatagccgtt
      781 gatggtctca agcacggttc aggaattggt tactgtgact atgtacttta tggtaaaaat
      841 gggaaaattt tagcgattgt ggaggctaaa aaagcctctg tcaatccaga agtaggggaa
      901 gtacaggtca aagaatatgc tgaagctctt gagaaacata tcggctatca gccaatttgc
      961 tttattacaa atgggttgaa gcactatata cttgatggtc cgaaccgccg ccagattgca
     1021 ggcttttact ctcaagaaga attgcaatta gtgatggata gacgtcatct tcaaaaaccg
     1081 cttgaggata tttctagtaa aattagggac gatatttccg ggcgtcacta ccaaaaacat
     1141 gccattgcaa gcgtttgtga agctttctct aatcatcgta gacaggcact tttggttatg
     1201 gcaactgggg cggggaaaac tcgtacagca gtttctctag ttgatatctt atcacgtcat
     1261 aactgggtaa aaaacgttct cttcttagcc gatagaactt ccttggttaa gcaagcctat
     1321 gattcgttta gaaaattact cccagatctt tccgtttgta acttcttaga agataaagaa
     1381 ggagctcaat caagtcgtat ggtcttttca acttatccga ctatgattgg agcgattagt
     1441 ggtcaagaag aagtaaatca acgccctttt actgttgggc attttgacct tatcataatt
     1501 gacgaatctc accgttctat ttatcagaaa tacaagtcca tttttgatta ttttgatgca
     1561 agaattgtag gcttaacagc tactccgcgt caagatttag ataaaaacac ctatggattc
     1621 tttaatttgg agaatggggt tccaacatat gcatatgatt tggaagaggc tgttaaagac
     1681 ggatatttag tagcctatca ttctatcgaa accaaactga aactacctac ggatggtcta
     1741 cattatgatg atttgtccga agaagaaaag gaacattttg atagcaaatt tgaagacaat
     1801 agctgtgaaa aagatattga tgggagtgta tttaattcct ttattttcaa taaaagtaca
     1861 gtagaaattg ttttaaatga actcatgaca agaggaattc agacagcctc gggtgatgaa
     1921 attggtaaaa ctattatttt tgctaaaaat catgatcatg cggaatatat cagaggtatt
     1981 tttaacaacc gctatcctga aaaagggagc gactatgctc aggtgattga ttatagtatt
     2041 aagcattatc agaccttgat tgatgatttt aaaattaagg agaagtatcc tcaaattgcg
     2101 atttctgtcg atatgttaga tacaggtatt gatgtaccag aggttgttaa tttagtcttc
     2161 ttcaagaaag tacgctctaa aactaagttt tggcagatga ttggtcgagg aacccgtcta
     2221 tgtaaagatt tatttggacc tgagcaggat aaggaaaact tcttggtatt tgattatggg
     2281 gacaattttg attattttcg tgcagatcca agagatggag agggtcgtca cattgtttcg
     2341 ctgactcagc gtttatttaa tatcaaagtg gacttgattc gagaacttca gggactccaa
     2401 taccaagaag atcagtttgc gagagcatac cgtcagcagc ttgtctcgga acttcaaggt
     2461 cgtatagaga gcttaaatga gttggacttc agggttcgta tggttttaga tacagtttat
     2521 agctatagga aattggaaag ttggcagaat ctaactgctg ttacaagtga aaccattcaa
     2581 aaaaatctct ctccgctttt atttgatgaa gataaagaag atgagatggc caggagattt
     2641 gatttgtggt tgcttcatat tcagttgggg caactgacag ctaaatcttc cactgttcat
     2701 atttcccaag tgatgaagac ggctagagct ctttctgcta ttggcaatat cccgcaggtt
     2761 tttgagcagg ctgaaattat caggaaagta caggagcctg aattttggaa agaagttaac
     2821 ttgtctgatt tggaaaaaat tcgtcttgct attcgagatt tattacagtt tttggataaa
     2881 acagaccgta aaccctacta tgttaacttt gaagatcgta tactctccac tgttcacgag
     2941 accacagcat ttttgcaggt caacgatctt cggtcttaca atgaaaaagt tgagcattat
     3001 ttgaaaactc atctggatga ggagtccatt tctaagctat accataataa aaagttgaca
     3061 tctgatgata tgcttgcact tgaaaaattg ctttgggaaa aattaggtag taaagcagac
     3121 taccaaagtc attatgaaaa taaggcaatt ccgagattgg ttcgtgagat tattggctta
     3181 gatagagagt ctgccaatcg tattttttct aaatttttgt cggatgagaa tcttaatgcc
     3241 aggcagattt catttgtaaa attgattgta gactacattg tagaaaatgg ttttttagag
     3301 acgaaagtgt taacgcaaga gccgtttaaa tcttatggtt ctgttcaact actcttccaa
     3361 caccaactac cagtacttcg taatattgtt caaatcattg aacttatcaa taatcgagct
     3421 ggagaagcgg cttaaattct aaagtgattg ccatgctgag actcatttaa aattaaaaag
     3481 agtagaaatt tatgctatat atgagaagtt ttattaggaa gaatgtcatc gttttcctag
     3541 aatacagtat cagttgttaa gtggttgata aatttcaaag tagatacttg taccacgatg
     3601 tttgttgatc gagttattaa caaaagagct actttgattt taaagaaata gaaaacaaaa
     3661 agccgagcaa gaattcaatt gcaggagaaa atgaaataat actcaatgaa aatcaaagag
     3721 caaactagga aactagctgc aggctgctca aaacactgtt ttgaggttgc agatggaagc
     3781 tgacgcggat tgaagagatt ttcgaagagt ataaatcttc ctaggataaa gcaaaacgca
     3841 tagtatcaag ggttttcaac acttgatact atgcgttttc tgatgttaaa gactttctac
     3901 caggtttttt aaaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg
     3961 gtggggcgaa ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga
     4021 tgataagaca gacatcatta ccacaaaggg tagcgatagc gtcagggaag ctcaaagtat
     4081 caatgataga accaaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt
     4141 gaactgggcg catccagaca agggcgtctt ccatgtagag ttcgagacgt ttttcccatt
     4201 ttgagatgga accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata
     4261 ggttcatatt tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg tcgttctcag
     4321 caagaagggc ttgcaactca gcctgtgtat gaatcttgtt ttttgtgata agagcgcgta
     4381 taagttggtg gcggtgttct gatttattca taataatgta actcctttta gcaaggtaag
     4441 gtaagcatgg actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg
     4501 atttcaaagt cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa
     4561 atagttggct gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact
     4621 aacagtaaat catttctatt ttgtaaatta aggtaacctt ttgtcacgac tcgttgtgcc
     4681 tctggtctaa atggcaattc acagagattt tccaacatgt gatagcgacc gttgtcaatg
     4741 gttctagcac ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc
     4801 agttgggcag ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg
     4861 cgaccgttta ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attggctttc
     4921 ccttgataga gctctgtatt gaaggtttgg tatgtcttac catagcgctc aaaatcctta
     4981 tctgggtact ggttttgaat agcttgctct tcttgaccaa gtgagaaggt ttcacagttt
     5041 tcttgcccac cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag
     5101 ataacagtag gaagttgaaa gtctgtttcc tgtcctagta atttcttggt taataaggca
     5161 tttatggact cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta
     5221 tggaaaaaga gatgcttgtg tatatgagta ggaagagcat ggaacatctg gtaaacatga
     5281 agtggtttga cattccaatc ctgagaacca tgagtaaaga caacctctgc ctttacttta
     5341 tgggcattga gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg
     5401 tctagctgag ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag
     5461 tcgccagcta agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct
     5521 ggataaccac ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa
     5581 attcctgcct cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg
     5641 gacatggtac ctagatagga aagtcctgtt gtagcaactt ttccgtttga ccaatcagcc
     5701 ttgacttgac gctggcgcgt gtgatcagta aaggcacggc aacgaccgtt aagccaatcg
     5761 atgacatttt tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag
     5821 tctttggtac caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg
     5881 tttagtgtat agctagagtt gatgtgagtt agcttttcct cagcctctgc tataagctca
     5941 gctttacctt ggggttggac gagatttagt tgaggtttct ctagctcaat cttgtgagga
     6001 agcttaacct caagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg
     6061 gttccctgat gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg
     6121 cgaataatgc taacctttac taggtctgat agcccttttt ggtcagtatc gacacgagac
     6181 tcaacgtaaa cgacttcacg aatgacatcc tggttagaaa aagtagccaa actcttgccg
     6241 ttaaagtagt ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata
     6301 agagtatttc cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca
     6361 ccatatataa tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc
     6421 aaataagaaa agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca
     6481 tcttctgatt gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatagaaagt
     6541 gggtagttgg tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct
     6601 ttgtgattgg ctgtattttg taaatcaaag ccacattttt ttagttcaga taagacattt
     6661 tcttttggaa aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg
     6721 acagttaagg ttattatatc aaaaaaaaag cagaaaggga attgttaact tcaaaaggaa
     6781 ataatccaat aaaaatgaat aaagtactaa attcaatata gagaacagag taacaataag
     6841 aataaataga tagggtataa aagttctagg agatttatat tatatgcttt ctatttttat
     6901 atacaatata gtataaatat aaaaatgatg acaaaaatac aaatgaatag aaaataaatt
     6961 agtaagctga tgaaattttt ctcaagagaa gccatttata ggtgaaaatg gtataatata
     7021 gtgagaagga tagaggagaa gtgtaaattg atcgcacaac tagatacaaa aacagtctat
     7081 agttttatgg aaagcgtcat ttcgatcgaa aagtatgtga gagcagctaa agaatacggc
     7141 tacactcatt tggctatgat ggatattgac aatctttatg gcgctttcga ctttctagat
     7201 attacaaaaa aatacggcat tcatcctttg ctagggcttg aaatgacagt gtttgtagat
     7261 gatcaggaag tgaatttgcg ctttttagct ctatctagtg tgggctatca gcagttgatg
     7321 aagctttcga cagccaagat gcagggggag aaaacttggt cagtcctgtc ccagtacctg
     7381 gaggatatcg cggtcattgt gccttatttt gatagagttg agttgttaga actaggctgt
     7441 gattactata taggggttta tccagaaaca ctagcaagcg aatttcatca tcctatctta
     7501 cctctttatc gggtcaacgc ttttgaaagc agggatagag aagttcttca agttttaaca
     7561 gcgattaaag aaaatctacc gctcagagaa gttcccttgc gttcgagaca agatgtcttt
     7621 atatcagcaa gttctttaga gaaactattc caagagtgtt ttccgcaagc tttggacaat
     7681 ttagaaaagc ttatttcagg catttcttac gacttggata ctagtctgaa actgcctcgt
     7741 tttaatccag ctagaccagc agtagaggag ttgagagagc gtgctgaact ggggcttgtt
     7801 cagaaggggt tgactagtaa agaatatcaa gatagactag accaagaatt gtctgttatt
     7861 catgatatgg gctttgatga ttatttcttg gttgtttggg atttgttgcg ttttggacga
     7921 tcgaatggct attatatggg aatgggaagg ggttctgcag taggcagttt ggtttcttat
     7981 gccttagaca tcacggggat tgacccagta gagaaaaatc tgatttttga acgctttctt
     8041 aatcgtgaac gctataccat gcctgatatt gatattgata tcccagatat ttatcgtcca
     8101 gattttatca gatatgttgg taataaatat ggtagtaaac atgcggcaca aatcgttact
     8161 ttttcaacct ttggagccaa gcaagctctt cgagatgtct tgaaacgctt tggtgtgcca
     8221 gagtatgaat tatctgcaat tactaagaaa atcagttttc gtgacaatct taagtcggcc
     8281 tatgagggca atctccagtt tcgtcagcaa atcaatagta agttagaata ccaaaaagct
     8341 tttgagattg cttgcaagat agagggctat ccaaggcaaa cctctgtcca tgcggctggt
     8401 gttgtaatta gtgaccaaga tttaaccaac tacattcctc taaagtatgg tgatgaaatt
     8461 ccactgactc agtatgatgc tcatggagtt gaggctagcg gacttttgaa gatggacttt
     8521 ctgggactac gaaatttgac ctttgtccag aagatgcaag agttgcttgc tgaaacagaa
     8581 ggtattcatc tgaaaattga agaaatcgat ttagaagaca aagaaacgtt agctttattt
     8641 gcctctggta atacaaaagg tatctttcaa tttgagcaac caggtgccat tcgtctgctt
     8701 aagcgtgtgc aaccagtctg ttttgaagat gtcgtcgcga ctacttctct aaatcgaccg
     8761 ggtgctagtg actatatcaa taattttgtg gcaagaaagc atgggcagga agaagtgact
     8821 gttctggatc cagtactgga ggatattttg gctccaacct acggcataat gctctatcag
     8881 gagcaggtta tgcaggttgc ccagcgattt gccggattta gtcttgggaa agccgatatt
     8941 ttgcgtcggg ctatggggaa aaaggatgcc tctgccatgc atgagatgag ggcttccttt
     9001 attcaaggtt cattagaagc tggtcatact gtggaaaaag cagagcaggt ctttgatgtt
     9061 atggagaagt ttgcaggcta tggttttaac aggtcacacg cctatgccta ctcagcattg
     9121 gccttccagt tggcttattt taaaacacat tatccagcca tattttatca gattatgttg
     9181 aattctgcca acagtgatta cttaatagat gcacttgaag caggttttga agtggcgcct
     9241 ctgtccatca acacgattcc ctatcacgat aaaattgcca acaaggccat ctatctaggt
     9301 ttgaaatcca ttaaaggagt cagtaatgat ttagctctct ggattattga aaatagacct
     9361 tattctaaca ttgaagattt tatagctaaa ttacctgaga attatctgaa acttcctctg
     9421 ctagaacctt tggtaaaagt tggtcttttc gattcatttg aaaaaaatcg tcaaaaagta
     9481 tttaataact tagctaatct atttgaattt gtgaaagagt tgggaagttt gtttggagat
     9541 gctatttata gttggcagga atcggaagat tggacggaac aagaaaaatt ttatatggaa
     9601 caagagcttt tagggatagg tgtcagcaaa catccactac aagctattgc aagtaaggct
     9661 atttacccga ttaccccaat cggaaatttg tcagaaaata gctatgctat tattttggtt
     9721 gaagttcaga aaataaaagt gattcgtacc aaaaagggtg aaaatatggc cttcttacag
     9781 gcagatgata gtaagaaaaa attggatgtc actctctttt cagacttata tcgtcaggtt
     9841 ggacaggaaa taaaagaggg agccttctac tatgtaaaag gaaaaataca atcacgtgat
     9901 ggccgtctgc aaatgattgc acaagaaata agagaagcag ttgctgaacg cttttggata
     9961 caggtgaaaa atcatgaatc ggatcaagaa atttcacgta ttttagaaca atttaaaggc
    10021 ccaatcccag tcatcatccg gtatgaagag gaacagaaaa ccatcgtttc tccccatcat
    10081 tttgtagcta aatccaatga attagaggag aaattgaatg aaatcgttat gaaaacgatt
    10141 tatcgctaaa aatacggaaa atagaagaat tttaaaatca aatgtgatat aatcaagaag
    10201 aatgttaaaa gaaaaaggag cataaaccaa tatgaaacgt attgctgttt tgactagtgg
    10261 cggagacgca cctggtatga acgctgctat ccgtgcagtt gttcgtcaag caatttcaga
    10321 aggaatggaa gtgtttggta tctatgacgg atatgctggt atggttgccg gtgaaattca
    10381 tcccctagat gcagcttcag taggagacat catttctcgt ggtggtactt ttcttcactc
    10441 agctcgttat ccagagttcg ctcaacttga agggcaactt aaagggattg agcaattgaa
    10501 aaaacacgga attgaaggtg tagttgttat cggtggtgac ggctcttacc acggcgctat
    10561 gcgtttgact gaacatggct tcccagctat tggtcttcca ggtacaatcg ataacgatat
    10621 cgttggtact gactttacaa ttggttttga cacagcggtt actactgcca tggacgctat
    10681 cgataagatt cgtgatacat catcaagtca ccgtcgtact tttgtaatcg aagttatggg
    10741 acgtaacgct ggtgatatcg ctctttgggc tggtattgca actggtgctg atgaaatcat
    10801 catccctgaa gcaggcttca agatggaaga tatcgtagca agcatcaaag ctggttatga
    10861 atgtggtaaa aaacacaata tcatcgtctt agctgaaggt gtgatgtcag cggctgaatt
    10921 tggtcaaaaa cttaaagaag ctggagatac aagcgacctt cgtgtaacag aacttggaca
    10981 tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt ttggcgtcac gtatgggtgc
    11041 acatgctgtt aaacttctta aagaaggtat cggtggtgtt gcggttggta ttcgtaacga
    11101 aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa ggggcattgt ttagccttac
    11161 tgcagaaggt aagattgtgg ttaacaaccc acacaaagcc gatattgagc tatctagctt
    11221 gaataagagc ttgtcataat ttacaattta gttaataaga ccaaaaaggt catatatata
    11281 aaggagtcac aaaaatcatg aacaaacgtg taaaaatcgt tgcaactttg ggtcctgcgg
    11341 tagaaatccg tggtggtaaa aaattcggtg aggacggata ctggggtgaa aaacttgatg
    11401 ttgaagcttc agctaaaaac attgctaaat tgattgaagc tggtgctaac acattccgat
    11461 tcaacttctc acacggcgac caccaagaac aaggtgagcg tatggcaact gttaaacttg
    11521 cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga tacaaaagga cctgaaatcc
    11581 gtacagaatt gttcgaaggt gaagctaaag aatattcata caaaactggt gaaaaaattc
    11641 gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt gattgcgttg aacgttgctg
    11701 gtgctcttga tatctatgat gatgttgaag ttggtcgtca agttttggtt gacgatggta
    11761 aacttggtct tcgtgtggtt gctaaagatg atgcaactcg tgaatttgaa gttgaagttg
    11821 aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat ccctaacact aaaattcctt
    11881 tcccagctct tgctgaacgc gataacgacg atatccgttt cggtcttgaa caaggtatca
    11941 acttcatcgc aatttcattc gtacgtactg caaaagatgt gaacgaagtt cgtgcaatct
    12001 gtgaagaaac tggaaacgga catgttcaat tgttcgctaa aatcgaaaac caacaaggta
    12061 tcgataactt agacgaaatt atcgaagcag ctgatggtat tatgattgct cgtggtgata
    12121 tgggtatcga agtaccgttc gaaatggttc cagtttatca aaaaatgatt atcaagaaag
    12181 tcaatgctgc aggtaaagtt gttatcactg caacaaacat gcttgaaaca atgactgaaa
    12241 aaccacgtgc aactcgttca gaagtatcag acgtattcaa cgctgttatc gacggaactg
    12301 acgctacaat gctgtcaggc gagtctgcaa acggtaaata cccactcgag tcagtaacta
    12361 caatggctac aatcgacaag aacgctcaag ctcttcttaa tgaatacgga cgtcttgatt
    12421 cagattcatt tgagcgtaac tctaagacag aagtaatggc ttctgctgtt aaagatgcta
    12481 ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa gacaggtcat actgcacgtt
    12541 tgatttctaa ataccgtcca aatgctgaca tcttagcatt gacatttgac gaattgacag
    12601 aacgtggctt gatgttgaac tggggtgtta tcccaatgtt gacagatgct ccatcttcaa
    12661 ctgacgatat gttcgaaatc gctgaacgta aagcggtaga agcaggtctc gttgagtcag
    12721 gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga agctgttcgc acaaacacaa
    12781 tgcgtatccg cacagtacgt taagaaaaat ataaaaacct atcatatcca gctttctagc
    12841 ctgtatgatg ggctcttttt ttgtccaggg ggcaaaaagg ggggcaaaac tttcataatg
    12901 gattgatact cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac cgtatatatg
    12961 ttactgactt cgtcagttct atctacaacc tcaaagcagt gctttgagca acctgcggct
    13021 agcttcctag tttgctcttt gattttcatt gagtatgaaa taagatatgc acaaattgat
    13081 tagaaagtca aatgaatttc tacaaatgtt ttagcaatcg taatgtactt gtctagattc
    13141 gatctgatat attttcgatt taatgatatg gtatttaaaa cctccaaagt agcttgctcc
    13201 attcttttac ttacgtgagt gtagatgtta tttactgttt tagcgtttta gcgtttttgt
    13261 gttccactct aaccattata gcattcttct cagctagtgt actaaggagt gtgtgcctga
    13321 aaatatggga actaaggggc tggtttatcg gtttctctag tttagtattt gccttttgca
    13381 aagtgatgtt aaatgccttt ctctaaattt acatatcact attgtttaac aaaatctaat
    13441 ctattttagg tcacttattc tttttttgaa atgtagaatg aactttttca aagtttttcg
    13501 aatcttttaa aatttgtttg ttttatatcg ccattctccc ccttttttaa ttctccctat
    13561 atagcctgac aactttcccg atggtacgaa tatggttgct ttcgtctagg tggatgtcgg
    13621 ggtatttggg attgagtttt tttaaggtag ccttggcgga gtttcttgac atagttagcg
    13681 ccgtctactt ggaagatgcc gatggtatta tagtcaatct gtggggtatt cttgataaat
    13741 aggtagtcgc tgtttcttat ctttggctcc atggacttgc tgacgacata agcgattggg
    13801 tcgtagtcgt ctgggataat ggaaactcca tatctaaatc gttgtcctgc atcgagcggc
    13861 tacctgcaga gataaactac ctaacacgag agtaagtagt ctgtctgtag tcgtccagtc
    13921 tgatgatttt tacgatactt cgtttttctg atcatacagt tgcctctcgg cataggtcag
    13981 aactttacct tgtctgggtg gtgcccgttg gtcgtagata gattggatat cgctaggaga
    14041 atccttttga actggagaaa agagggcatc aatcaagcta ctgaatactt taactaagtc
    14101 aaatatagta tttttcttag tagacctaac ccttttttca taatttctaa tggtgttttt
    14161 acttatacct atcttagtac ccaattctta ttgagtccaa ccattactag tctatattgt
    14221 tttatagttg attgagtttg gaatagtacg ctgtagctgc taaaacattt ctaggaatta
    14281 atttgccttt cctaatagag ttgttcatat cttatttcaa tctactatat ttttcgcctc
    14341 taacaatcgc aatctcttct ttatctacga atgaaatcgc tttctatttt tgtaagtaaa
    14401 gcatcacacg aaatccacga aaatgaaaac ctttgttgtg ttttcgtaaa aaatttgttg
    14461 acagagcacg aaacgcctac tataattaaa tcaagcttaa ggaaataaca aaaaaacaaa
    14521 tcggagggaa agacgatgaa cacattaaat gagaaagtaa tcaatatctg taaagcagta
    14581 gttaaagaaa ctttaatcca agacatttag gagaaagaaa tgaagaaatc aagaaaatta
    14641 gccacattag gaatctgttc agccttgttt ttaggcttgg ctgcttgtca acaacaacat
    14701 gctacttctg aggggacgaa tcaaaggcaa agcagttcag cgaaagttcc atggaaagct
    14761 tcatacacca acctaaacaa ccaggtaagt acagaagagg tcaaatctct cttatcagct
    14821 cacttggatc caaatagtgt tgatgcattt tttaatctcg ttaatgacta taataccatt
    14881 gtcggctcaa ctggcttatc aggagatttc acttccttta ctcacaccga atacgatgtt
    14941 gagaaaatca gtcatctctg gaatcaaaag aagggcgatt tcgttgggac caactgccgt
    15001 atcaatagtt attgtctttt gaaaaattca gtcaccattc caaagcttga aaagaatgac
    15061 caattgcttt tcctagataa tgatgcgatt gataaaggaa aggtctttaa ttcacaagat
    15121 aaggaagagt ttgatattct attttcgaga gttccaactg aggcaactac agatgtcaag
    15181 gttcacgctg aaaagatgga aacattcttc tcacaatttc aattcaatga aaaagctcga
    15241 atgctgtctg tagtcttgca cgacaatttg gatggcgagt atctgtttgt aggccacgtt
    15301 ggggtcttag tacctgctga tgacggtttc ttatttgtag agaaattgac tttcgaagag
    15361 ccctaccaag cgattaaatt tgctagtaag gaagattgct acaagtattt gggcaccaag
    15421 tatgcggatt atacaggcga gggactggct aagcctttta tcatggataa tgataagtgg
    15481 gttaaacttt aatagtgtta tgatatgaca gtaatcttag gatttttatt tctatttttg
    15541 atgacttggt gggttatttc aatcgttaat agccagaaac cactcaaaaa tgaaacattt
    15601 attggctatg tccaaagata cgatattgat gggaatggct atcaatcatt accgtgtcct
    15661 cagaactgag aggagttctt gaaatcgtaa aaccactttg aacaagagtt acttcaaccc
    15721 attggctctg atggattaag ttgctttcgt gaataccaaa atcagccgca atttgttcat
    15781 aagtgcggta ttctcgcaca tattgaagag tggccataag aaggtcttct aggcttaatt
    15841 taggttttcg tccacctttt gcgtgtttaa gttgataagc tgtttttaat acagctaata
    15901 tctcttcaaa agtcgtgcgc tgaacaccaa caagacattt aaatcgtgca tcagttagtt
    15961 gtttacttgc ttcataattc atagaactac tataccatat tttgtttcgc aggaagtcta
    16021 atgctaaaat cttatcagtg agaagatttc ttaaagttta ttctttgtag tttcatctgt
    16081 attagtacat aatttaactt agagaaaata ggaggactaa tcgaatggaa ttaaaagatt
    16141 ttacagaaaa agaacaggaa atgattaaga aaaggcttac aatgtctaat attagtgaca
    16201 aagaaactac tgagaagatt ctggcgctag taccacaaga cttgattaag cgaatcccgt
    16261 tttttgtcag aaaacatgct acaacacgta cgattaaacg catttcaatt gaacaccctg
    16321 aactctacgc tgtagctcaa acaagtggtg agattccgga aaaagaacgc gaagaattgc
    16381 gtcagattat cacgactatc tttgaacaaa agatgaataa gcatagtatt aagtagagaa
    16441 tgaaaaaata ttttattagc ggtttgggaa gcaatgccta tcatagcaag gatttttttc
    16501 aagaactaga ttcgcaggtc tattttctaa atccatatga aaagcatctt cgagatgaaa
    16561 cagaattgaa atcatggttt aaaaatgaga ttgtagagga agaatctatc tgtctgatag
    16621 gtcattctct tggaggagat ttagctcgtt attccgcatc ggaatttgaa gaagtaaaga
    16681 aactgattct tttggatggt ggctatctag atttagataa gattttacct ttggatacag
    16741 agttagagga aactaaaaat tatatcaaat ctcaaattgt ttcggactta gctcttctta
    16801 cttctaaaga aaaatctgaa gcaaagcatt ggtcagaaaa tatggagaaa gctgtaagac
    16861 agtcctatca ctggaatgtt gagtataata gatatgagtt ggctataaat tatgaaaata
    16921 tagaagcgat actccgccta cggagaaaaa tacaagcttt taagagagaa gtgggagata
    16981 ccttgtttat tagtcctcgc tatcctaatg aagctacatg gagagaggaa gccctaaaag
    17041 aattgccaga ctattttgat actatttttt tagaaaactt tggccatgag ctttatactc
    17101 aagcacctaa agaaatcgct agtctaatga atgagtggct cgcttatttt ctatgagcta
    17161 cttgtattgc tggaaatggt ataagatgaa aatctacaag tcactaattt tcatataacc
    17221 aaaaaacgaa caggctcttt ttctgttatt cagaagagaa cttgttcgtt tttatcttga
    17281 ttttcttaaa aagctctata tacataggga ttttctggtt tatcgacttt ggtaaagctg
    17341 tcgatttcca aggttggaag gttttgtttg agttctttat ggtagtgatt gaccagtttt
    17401 cctttggctg aaatccaagt gttgttttca tactgccggg tattgccctt ggtcagcaat
    17461 ccatagacac cagaatctgc gatacagtgg ataataccga atcggaacag aaattgacta
    17521 ttggcatgac tggggtcgtt atagacaaag cctgtaaact ggattgtctt gccctcaaac
    17581 tcatctggat agtcgtagat agcctccatg acttccatat agttttcatt agtgatctga
    17641 atactatctt gggataagta tttatccgcc gccgttcgca tttccttttc ataggctgat
    17701 tttgaaaaat aagaactggt atctggtttc aaatattggc ttgtcgtccc ttcgcttgtc
    17761 tgaatggcta gatccgttcc ttctgatagg gggaaatgat aacctttagc agaaacggtc
    17821 tgagaatcca agctaacagt tgggaaagtt aagccgatga taagtggaat agccagaaga
    17881 gaaatactcg tcatcttggc caatcggctg ttcagatgac tgtgggtttt gacttgcttc
    17941 atccagatat acaattgaac aattgccaag ataaaggaaa gcaccatgga gatataggcc
    18001 agataggaat agtgcatgtt gatgtactgg tttagtttgc ccgacagatg gaggtaaata
    18061 gtcagttcaa aatagccagc taaaactaaa aatcgaatca taggatgact ccaatcaaga
    18121 gagaataggc taaaacgacc agagtcacaa tcgtaatgaa gtgactaata aatcgtgctt
    18181 tcaagtaatt tttcatcatg agaatatttt tgatatccag cattgggcca atgacgagaa
    18241 aggccagaac tggtgcccaa ccgaaactcg agagtagaga agcacctata aaggcatccg
    18301 cctcactaca gagcgaaaga agaaaggcca aaagcatcaa gagcaggatg gcaaaaagag
    18361 gagtcgcact gatagaggtc agaatccgag tcggaacgta gacctgtatt atagaagcaa
    18421 agaggcagcc aaataccaaa taacgccccg tatcaaaaaa ttcatcaatg gcctgcacaa
    18481 agacttgaaa aacttttttt gcagaactca agtaagaaaa atcatgctca tgacaagcca
    18541 gacgattttc tttctgaatc ggttcttgcc agaaaaatcc tagaaaaatt cctagtatta
    18601 cagccacaag aatggaaccc agagctcgta atagggcgac atggaaggag ttgccaaagg
    18661 cagaataggt cgcaaaaaga acaatgggat tgataacagg tgctgtcaca agaaaaggaa
    18721 cggccgtgta acttggaacc tttttttcca gaaaacgatt gatgatgggg acgattccac
    18781 attcacaaga agggaaaagt ataccgacaa aggtcccaaa aaagattctc ccccaacgat
    18841 ttcgagggag aaaatgataa accttgtcag gtgtgatata aacttcaatc agccctgaga
    18901 caatgcttcc tatcagaacg aagggaaggg cttcaatgat aatggagaga aaaatggctc
    18961 cagtttgaag tacactagat gggagttgtt gaaaagcagt catctagttt ttcttttctg
    19021 ctttgacttt tttctctttg tcatcaggga aagtaacttg tttcaaatca gggagtttag
    19081 caaactcttc aaacatcttg tccaagtcgt ctcgttttgt aaatttgaca gccataggtg
    19141 tacctcgatt ctaaattcta cctctattat actattattt tgcggaaaag ggagtttttt
    19201 aatttgtttt cgatagttga tacacttcga aaatctcttc aaaccacgtc agcttcgcct
    19261 taccgtagta cggttactga cttcgtcagt tctatccaca acctcaaaac agtattttga
    19321 gcagcctacg gctagcttcc tagtttgctt tttgattttc attgagtatg aaaaggattg
    19381 gagaaagcct tccagcttgt ggtataatag atttatggat aaaaaatatg aaaaaatctc
    19441 tcaggatttg ggagtgacgt taaagcaaat tgataccgtt ctaagtttga cagctgaagg
    19501 ggcgactatt ccctttatcg cgcgttatcg caaggacatg actgatagtc tggatgaggt
    19561 ggcgattaag gctattattg atttggataa aagtctgaca aatctcaatg accgtaagga
    19621 agctgtctta gctaagattc aagaacaagg taagttgacc aaggaattgg aagaagctat
    19681 cttagttgcc gaaaaattag cagacgttga agaactctat cttccttata aggaaaagcg
    19741 tcgtaccaag gcaaccattg cccgtgaagc tggactcttt cctcttgctc gcttgatttt
    19801 gcagaatata gttgacttag agaaagaagc tgaaaagttc gtctgtgaag gatttgcgac
    19861 tggcaaggaa gccttgaccg gtgcagttga tattttggtc gaagccttat cggaagatgt
    19921 gaccttgcgt tctatgactt atcaggaagt gctgagacac tctaaactta cttctcaagc
    19981 caaggatgaa agtcttgatg aaaagcaggt ttttcagatt tattatgatt tttcagagac
    20041 agttggaact atgcaaggct atcgtacctt ggctctcaat cgtggggaga aacttggtgt
    20101 cttgaagatc ggttttgaac atgcgacgga ccgtattctt gccttctttg ctactcgttt
    20161 caaggtgaaa aatgcttata ttgatgaagt tgttcagcaa tccgttaaga aaaaggtctt
    20221 gcctgctatc gagcgtcgta ttcggacaga attaactgag aaagctgaag aaggagctat
    20281 ccaacttttt tctgacaatc tgcgcaatct cctcttggtt gctccactga aagggcgcgt
    20341 ggttcttgga tttgacccag cctttcgtac aggtgccaag ctagctgtcg tggatgcaac
    20401 aggaaaaatg ctgacaactc aggttattta tcctgttaaa ccagcatcag ctcgtcaaat
    20461 cgaagaagcc aagaaagatt tagcagattt aattggtcaa tacggtgtag agattattgc
    20521 cattggaaat ggaacggcca gtcgtgaaag tgaagctttt gtagcggaag ttctgaaaga
    20581 tttccctgaa gtcagctatg ttatcgttaa tgaaagtggt gcttctgtct attctgccag
    20641 cgaacttgct cgtcaggagt ttccagactt gaccgttgaa aaacgctctg ccatttctat
    20701 cgcccgtcgt ttgcaagatc ctcttgcgga attggtcaaa atcgatccta agtcaattgg
    20761 tgtcggtcaa taccaacacg atgtcagtca gaagaaacta tctgagagtc tggactttgt
    20821 tgtcgataca gtggttaacc aagttggtgt caatgtcaat acagctagcc cagctcttct
    20881 ttcacacgta gctggactca acaaaactat ctctgaaaat attgtcaaat accgcgagga
    20941 agaaggaaaa atcacttcac gcgcccaaat caagaaagtt cctcgtctgg gagccaaggc
    21001 ctttgagcag gctgctggtt tccttcgtat ctctgaaagt agcaatatcc ttgataatac
    21061 aggagttcac ccagagaatt acactgcagt taaggaactc ttcaaacgtt tagatattaa
    21121 agacctaaac gaagaagccc aaagcaaact caagtcgctt tcagtcaagg aaatggcgca
    21181 agagttagac cttggtccag aaactcttaa agatatcatt gcagatcttc tcaaaccagg
    21241 tcgagatttc cgtgattcct ttgacgcacc tgtgcttcgc caagatgtcc tagatatcaa
    21301 ggacttagtg gttggacaaa agctagaagg agtggtgcgt aacgttgttg atttcggtgc
    21361 ttttgttgat atcggaattc atgaggacgg tctcatccat atttcccata tgagtcgcaa
    21421 gtttatcaaa caccctagtc aagtggtggc agttggagat ttggtgagcg tttgggttaa
    21481 gaaaattgat actgaacgtg aaaaagttaa tctgtctctc ctagctccaa atgaaactga
    21541 ctgattacgt caagcaggtt tcactagaag acttcggcag accttttatc catcatgtcc
    21601 agtggaatag gcgtctacgt tcgacaggtg ggcgattttt ccccaaagat gggcatttgg
    21661 attttaatcc caaggtttat caggaactgg ggttggacgt ttttaggaaa attgtccgac
    21721 atgaactctg tcattatcac ctctattttc aagggaaagg ctatcaacac aaggatcggg
    21781 attttaagga actgttgaaa gcagtggatg gattacggtt tgtaccatcc ttgcccaata
    21841 gtaactccaa gccaatcaag ctctatcgtt gccaatcctg ccagcaaagg tatcagcgta
    21901 agcgtaggat tgatacccaa cgctatcgct gtggactttg tcgaggaaag ttgctattag
    21961 taaatcagcc tgaggactga tgaaagccga gcctatccgt gatatactag tctaacctag
    22021 cagaaagagg aaatatcatg aacagtaagt tttataaaat gagacgaaat cgcatgattt
    22081 caggagtttt agcaggtctg tcagacaagt ggaactttga tgttaccctt gtacgttttc
    22141 tgtttgccat ttttacagtc gcaaactttg gacttggggt gattatctat atcatcctag
    22201 cttctatcat gccaaccaag gaagaaatcg aagcagaaat gtacggaaca ggcccacgta
    22261 aacgcaaaga agctcaagcc attgacgata atgaaggctg gttttggtga ggttttacaa
    22321 aagatttgga atacgcaaaa agctttaaat caatagtcta aactgcttga tttaaagctt
    22381 ttttactttt atactcaata aaaatcaaag tgcaaactag gaagccagcc gcaggctgta
    22441 atttagtcgg caatgtgaag ttgatatagt ttgcactttg atttttgaat agtattaata
    22501 atatttcgcc agcttcatcc acaaactata gtggattgga actagaatag gacacctata
    22561 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttatt
    22621 tcattttact ataaaagcag taatttaaac gcagtttttt aatctatttt tgctgttgag
    22681 acaatacatt tttggaaaaa tggtggatgc tgataacaac tgataaccag caaataacat
    22741 aagcagtgcc ggtaaattct gtactgataa agtgtgtgtg ttcaactaag agctgaccga
    22801 tgaatggaga gagcagatag agaagtccga tgagtatatg ttctttgtgt ttcattaaag
    22861 cgcaccttct ttccttatag gttgaacgac ttgcaagtgt taaattgaat ggtatgttat
    22921 ctaggtaagc ttactaaaat gttagttccc gcttcctcct tttcaaagta agccttttca
    22981 cacttatatt ttacaacttt aaaaatagga aatcaaatca ttttctaagt aattttgctt
    23041 atatttcacc caatcttaca aaaatgtaag attaaagtct cttttgtaag gttaggttat
    23101 ggcaagcggt ctttttttga tgtaaactag actcataaag aacaaaggag taacatcatg
    23161 aaacaaatct tacataagaa aactagaaaa ccaagtcaca aagaaattga gcgcgttcag
    23221 ctgggatgca ctatgatgca agctacattt catttgatgg gatattaaga aaggagattt
    23281 tcatgacact tttagatgta aaacacgttc aaaaaattta taaaacacgt tttcagggca
    23341 accaagtaga agccctcaag gatattcact ttaccgtaga aaagggtgac tacgttgcca
    23401 tcatgggtga gtctggttct ggtaaatcaa ctcttctcaa tattctagct atgttggata
    23461 aaccaagtcg tggtcaggtt tacttgaatg gaactgacac cgcaactatt aaaaattcac
    23521 aggcttctag tttccggcgt gaaaagctag gatttgtctt ccaagacttt aacttgctag
    23581 atactctgtc tgttaaggac aatatcttgc ttccgcttgt cttgtcaaga agacctataa
    23641 cggagatgat gaagaaattg gtggtgacag ctgagaatct gggtattaac caattgcaag
    23701 agaagtaccc ttacgagatt tctggtggtc agaaacagcg tgtagcagta gcccgcgcca
    23761 tcatcacaga acctgaaatt ctccttgcgg acgagccaac aggagccctt gattccaagt
    23821 catctgcagc cttacttgat gtctttaatg aaatcaatga gcgtgggcaa accatcctca
    23881 tggtaaccca ctcaacagca gctgctagca gggccaagcg tgttctcttt atcaaagacg
    23941 gcattcttta caaccaaatc taccgtggag agaagacaga gcgtcagatg ttccaagaaa
    24001 tctctgatac cttgactgtc atggcaagcg aggtgaatta gtatgtttcg attaaccaat
    24061 aagttagcgg tatcgaactt gattaaaaac cgcaaactct actatccctt tgcactggct
    24121 gttctcttgg cagtcaccat cacctatctc ttttactccc taaccttcaa tccaaagatt
    24181 gcggaaatcc gtggaggaac caccattcaa gcaacacttg gatttggtat gtttgtcgtt
    24241 acccttgcgt cagccattat cgtcctctat gccaatagtt ttgtcatgaa aaaccgttcc
    24301 aaggaactgg gtatatatgg catgttaggc ttggagaagc gccatctaat cagtatgacc
    24361 tttaaggagt tagtgctatt tgggattcta actgttggag caggaatcgg tattggagcc
    24421 ttgtttgaca agttgatttt cgctttccta ctcaaactga tgaaattgaa ggtggaactg
    24481 gtcgctacct tccagatgaa agttgttatt acagtacttc ttgtctttgg attgattttc
    24541 ctaggcctca tgttcctgaa tgcccttcga atcgcccgta tgaatgccct ccagctctca
    24601 cgtgagaaag ctagcggaga gaaaaaaggt cgcttccttc ctctccaaac gattcttggt
    24661 tccataagtt tagggattgg ctattatctt gcccttacgg taaccgatcc tcttacagcc
    24721 ctaacaacct tcttcctagc tgttttgctg gttatctttg gtacttatct attgtttaat
    24781 gcagggatta cagtcttcct acaaatctta aagaaaaaca agaaatacta ttaccaacct
    24841 aataacctca tatctgtttc caacttgatt ttccgtatga agaaaaatgc ggttggacta
    24901 gcaaccatcg ctattttgtc aacaatggtt ttggtaacca tgtcagcagc gacaagcatt
    24961 ttcaattccg cagaatcctt taaaaaagtt ctaaatcctc atgattttgg ggtttcaggg
    25021 caaaatgttg aaaaagaaga tttggacaaa ctcttgagcc agtttgcaag tgacaaaggt
    25081 tatagtgtca aagagaaaga agtacttcgt tacagtaact ttggtattgc aaatcaagaa
    25141 ggaaccaagt taactatttt tgaaaaagga caaaaccgtg tccaaccaaa aacagttttc
    25201 atggtatttg accaaaaaga ttatgaaaat atgactggtc aaaaactgtc tctatcagga
    25261 aatgaggtcg gtctctttgc caaaaatgac ggactgaaag gacagaaagc tctaactcta
    25321 aatgatcatc aattttctgt caaagaagaa tttaataaag atttcattgt caaccatgtt
    25381 ccaaataagt ttaatatctt gactactgat tacaattacc ttgttgttcc tgatttacaa
    25441 gcctttttgg atcaattccc agattcggct atctataatc agttttacgg tggtatgaat
    25501 gtagatgcca gcgaagaaga acaactcaag gtcgctgagg agtatgaaaa ctacctcaat
    25561 caatttaatg ctcaattaga cacagaaggt agctatgttt atggtagcaa tctagcagat
    25621 gctagtgctc agatgagtgc cctctttggt ggtgtcttct ttatcggtat tttcctatcc
    25681 attatcttta tggtcggaac tgttctggtc atctactaca aacaaatttc tgaaggctac
    25741 gaagaccgtg aacgctttat tatcttgcag aaagtcggtt tggaccaaaa gcaaatcaag
    25801 caaaccatcc acaaacaggt tttaactgtt ttcttccttc ctttgctctt tgccttcata
    25861 catctcgcct ttgcctacca tatgcttagc ctgattttaa aagtgattgg tgtactggat
    25921 acgactatga tgttgattgt gaccttgtct atctgcgcta tcttcctcat cgcctatgtg
    25981 ctgattttca tgattacttc aagaagttat cgcaagattg tgcaaatgta aaaaagatac
    26041 ctcgacttca aaatcgaggt atttcttgta ttttaaatgc tgaaaagttg ttcgagcagg
    26101 aaggtaactc ccatggtcaa gagaccaata gcaaggttcc gaatcatagc tgttttggtt
    26161 ggggcttttc caagtctagc acttgtgtaa ccagtgagaa gaagggccac accgacaata
    26221 aggacggtag cagggatgcg gtaatcactt ggaaaaatgg tcactgacag cattggaggc
    26281 aaacttctaa ggaaaaaggc aacgaagcta gaaatggcag cgtgccaagg attggtaaat
    26341 tcttcatact caatcccata tttttcctct accagagcct tgagtggatt tttaagaaag
    26401 atcttattag tcaagagttg ggcagaagtt ttgaattctc cattttggat ataagaagca
    26461 tagagggatt ttttggctag ttccctatct tggtctagca agagtttttc tcgcgaaacg
    26521 gcagcttcct cggtatcttt tggagttgaa acggatacat attctccacc agccattgaa
    26581 aaggcaccag ctaagatagc cgcaaaacct gataaaaaga taatccagat attgctcgtg
    26641 gcactggcaa ctccgataac cacaccagca atggaaataa ttccatcgtt agcatcaaga
    26701 acacccgcac gcaggatatt taaacgacct gcaaaatttg aatcaatttc gtgatttgtt
    26761 tctgacgcta aatttcaagt tcaagttagc catccagaag tcttctctgg gtgacttgta
    26821 gtccaagcat tttttaggat agttgttaat ccacttttcg atgaatgcga cttctttggg
    26881 agtcattttc ttgattccct taggtaacca tctacgaatg agcctgttgt gattctcatt
    26941 agttcccctt tcccaagagg cataggggtg cgcataatag atgtgctcct cagaaaatac
    27001 atcaaataag cgattgaatt ccgttccatt atctgccgtg atggaaagaa tcttgtgttg
    27061 ttttaagatg agttttagag cctgattgac cacatcagca cttttatttg gaatcaatcg
    27121 gatgatctga tgtctactct ttcgatcagt caagacaagc aaacagtagt ttttcgctct
    27181 cgtaagtaga accgtatcaa tctcataatg cccattctcc aagcgaagat tgatagcttc
    27241 agaccgctgt tcgatggatt gaccagcagg tttaaagttg gtgctagcct gtttcttaag
    27301 cgcttttcct tttctagggt aaagcagatc ctgtttgctt aaccccaatt ttccatgatg
    27361 aatccaatag taaatggttg aaattcccac gttaacccct ttaaccatca ccatcatttc
    27421 aggcgaaaat ttttggttat gatagtggag aatcttttcc tttagttcct tggtcacgct
    27481 tgatttcctg accgagcgct tgcgattgtt ttcataagac tgttgagcat agtcggcaga
    27541 ataaacctct ttgaagcgcc cttttccaag acattgtcgg actgtcccac gcttgatttc
    27601 agtgtggata gtttgaggaa cttttccaag cagagaggca atttctctat ttgatttccc
    27661 ttcttttttc catctttcga ttaagcgacg gctatcgatt gtcaaatgtt tggcttttgt
    27721 agtataattg tcttgcatct ctgtgccttt cttgtgtttg tggttgaaca acaagtataa
    27781 cacagaggtg ttttcttatg cctacaagag ctatcagcta gttgaaccat ctaattttta
    27841 ggagggctgg gtggctaact tcattataga actttcattt acgaacatat agtaaaatga
    27901 aacaagaaca gaacaaatcg atcaggacag taaaatctat ttctaataat gttttagaag
    27961 cagaagtgta ctattctagt ttcaatctac tatatttttg ttttttatca aaaaatactt
    28021 tacaagttct taaaaacatg atatagtaat aaagcttaga aaatgagatg atgttttcta
    28081 gcaaatataa acccgagtaa aaaatgccta cggacaggca gggttgaatg ccgaagcgtg
    28141 gttgaaaagc cacattattg atagggttaa aagcctactt ttataagttg atgttaggac
    28201 acttgtccta attcataaat ttttagtgtg gtgaaagcac acgtcatctt gtgaaacgat
    28261 caataaagta cgtaatattt gctactagag agttaggaaa catcgggaac agacatactc
    28321 aacagaaacc aaaataaaca cgtcagaaga ttgcagagca ggtgaaaacc tgctcttttt
    28381 tcatgagtca acctttagtt ccttagtttt cataaggtcc taaaaatatt gaaaggagta
    28441 tgttttgaaa gagttagatc aaaaccaagc cccaatttat gaagccttgg tgaagttacg
    28501 caagaaaagg attgttccct ttgatgttcc aggtcacaag cgtggacggg gaaatccaga
    28561 acttgtcgaa ctcttaggag aaaaatgtgt aggcattgat gtcaattcga tgaaaccctt
    28621 ggataattta ggccatccta tttcgattat tcgtgatgca gaggagctgg ctgcagatgc
    28681 ttttggagct agccatgcct ttctaatgat tggtggaaca acttcatcgg tgcagactat
    28741 gattctggca acctgcaagg caggagataa gattattctg ccacgaaatg tccataaatc
    28801 tgctatcaat gcgttggttc tatgtggtgc cattcccatc tatatcgaga tgagtgtaga
    28861 tcctaagatt ggtatcgctt taggtcttga aaatgaccga gtagcacagg ccataaagga
    28921 ccatccagat gctaaggcta tcctaatcaa caatcctact tactacggca tctgttcaga
    28981 cctaaagggg ttgacagaaa tggctcatga agctggcatg atggttttag tagatgaagc
    29041 ccatggagcg catttgcatt tcactggtaa acttccaatt tctgctatgg atgcaggagc
    29101 tgatatggca gcagtttcca tgcataagtc tggtgggagt ttgacacaaa gttcgcttct
    29161 tttaatcggg gagcagatga atcccgagta cgttcgtcag attataaacc tgacccagtc
    29221 tacatctgcc tcttacttat tgatggctag tttggatatt tcacgtcgca acttggccct
    29281 tcgtggtaaa gagtcgtttg aggaagtcat tgagctatcc gagtacgctc gtcatgaaat
    29341 caatgccatt ggcggttact atgcttactc aaaagagtta atagatggtg tgtcggtctg
    29401 tgattttgat gtaaccaagt tgtcagttta cactcaggga ataggcttaa caggtatcga
    29461 ggtttatgac ctcttgcgag acgaatacga cattcagatc gagtttggtg atatcggcaa
    29521 tatcttggcc tatatttcca tcggcgaccg catccaagac atcgagcgct tggttggtgc
    29581 tctggctgat attaagagac tctattcacg agatgggaag gacttaatag ctggagaata
    29641 tattcagccc gagttggtgc tgtctccaca agaagccttc tattcagaga gaaaaagttt
    29701 gaccttagat gagtctgttg gacaggtctg tggagaattt gtcatgtgct atcctccagg
    29761 gattcctatc ttggctcctg gtgaacgcat tacacgagaa attgtagact atatccaatt
    29821 cgccaaggaa cgtggttgct ccctccaagg gacggaagat ccagaggtca atcatatcaa
    29881 cgttattaag agaaagacaa actataagaa aagtcaatag ttttatctaa actatttctt
    29941 atttcaattt gatgatttgg cgatgatttt agagcacggc aaaaagccct tgaattagaa
    30001 gcggtcaatc gcttaatttc tatcagctta tcaaatcctg cctcaatcct tttctgagga
    30061 ttagggtagc gtgtcaagag ttggtaggta tattctgaat gctttccaac gattttatcc
    30121 aactcaggaa agatgatatc aagacaacga gtgtattgta ctttccaatc agactgtttt
    30181 tcttgagacg atgaatatgt ctagccagta tttttagttc tacttgccga ttatcgtgtt
    30241 gaaattgttc acgattgggg tcagaaagaa gtttaagagc gatgccatga gcgtctttct
    30301 tatccgtttt agtcttgcga agtgataatg atttggcaaa ttccttgatg agcaaaggat
    30361 tgtaggtgta aactttatat ccttgttcat gcaggaagtt cagtagatta aaggcataat
    30421 gtccagtatc ttcaagagcg atgagacagt cttggttgag ctgtcgaaga gacagatcta
    30481 agagttcaaa accagcttta ttatttgaaa aagtgagtgg tttaagaaca gtttttcctt
    30541 gaacattcaa ggctgtaaca tcgtgtttat ttttagcgat atcaatgccc acataaagca
    30601 tgggagtacc tccagatgta gtatttcaag tctacttggt tatccacgaa ctttttgcct
    30661 tgttacctta gacgagataa aacgtctatg cgttatcaaa ctcattacca attgaaacaa
    30721 aagctgtggt tagagccttt cggaaatcgt caagcgattg gaggaaatga actaatccac
    30781 agtggcttat tccaagtata ccacttgggc tttggcagta gctaactgcg ctaaatataa
    30841 tataaggaga aatagatgga tttatggttt tctgaagttc atactccaga tgtcaaattg
    30901 tctctgagaa cagccaagca actttacgct ggaaaaagtg aatggcagga tatcgaagtc
    30961 ttggatacgc cagcttttgg gaaaatactg attttaaatg gccatgtctt gttctcagat
    31021 gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc ccatggctgt ccacccaaat
    31081 ccaaagaaag tattggttat tgggggtggt gacggcggtg ttgcccaagt attaacactc
    31141 tatcctgaac tggaacaaat cgatatcgtg gaaccggatg agatgttggt cgaggtctgt
    31201 cgtgagtatt tcccagactt tgctgcaggg ctagatgatc ctcgtgttac catttactac
    31261 caaaatgggc tacgcttttt gcgaaactgc gaagatgatt acgatattat catcaacgat
    31321 gcgacagatc catttggcca tacggaagga ctctttacca aggaattcta cggcaatagt
    31381 tatcgagctc tgaaggaaga cggcatcatg atttaccagc atgggagtcc cttctttgac
    31441 gaggatgagt cggcctgccg aagcatgcac cgcaaggtca atcaatcctt tccaatcagt
    31501 cgggtttatc aggcccatat tccaactagc ccagctggct attggttgtt tggatttgca
    31561 tcgaaaaaat accaccctgt caaagatttt gacaaggaag gttggaaaaa acgccagctt
    31621 ttcacagaat actacactgc aaacttacac gtgggagctt ttatgttgcc caagtatgtt
    31681 gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg tttactagtt attggttgtg
    31741 ggggcgttgc ccaagttgct atttcaaaaa tttgtcaaga tagcgaaaca tttacagaga
    31801 ttatgattgc tagccgtacc aagtcaaaat gcgatgactt gaaagcgaag ctagaaggca
    31861 aaacaagtac taaaattgaa actgcagcac ttgatgctga caaggtagaa gaggtcatta
    31921 ccttgattga aagctacaaa ccagaagctg ttttgaatgt agctctgcct tatcaagatt
    31981 taaccattat ggatgcttgt ttggcaacag gtgttcacta tatcgataca gccaactacg
    32041 aagcagaaga cacagaagac cctgagtggc gtgctatcta cgaaaaacgt tgtaaggaac
    32101 ttggttttac agcctacttt gactactcat ggcagtgggc ttatcaagag aaattcaaag
    32161 aagcaggctt gactgctctt cttggttctg gttttgaccc aggtgtaact agtgtctttt
    32221 cagcttatgc cctcaaacac tattttgatg aaatccatta tatcgacatt ttagactgta
    32281 atggcggtga ccacggttat ccatttgcaa ccaactttaa tccagaaatt aatctccgtg
    32341 aggtttctgc gccaggttct tactgggaag atgggaaatg ggtcgaagtc gaagctatgt
    32401 ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa agatatgtat ctccttcacc
    32461 atgaagaaat cgaatcattg gccaagaaca ttccaggtgt caaacgcatt cgtttcttta
    32521 tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct tgaaaatgtt ggactccttc
    32581 gtacggatac cattaacttt aacggccaag aaattgttcc aattcaattt ttgaaagcct
    32641 tgcttccaga tcctgctagc cttggcccac gtacagtcgg aaaaaccaat attggatgta
    32701 tctttacagg tgtcaaagat ggcgttgaaa agactatcta catctacaat gtttgcgacc
    32761 atcaagagtg ctatgcagaa gtcgggtcac aagcaatttc atacacgaca ggcgttccag
    32821 ccatgattgg gacaaaatta gtcatgaacg gaacttggaa acaagctgga gtgtataacc
    32881 ttgaggagtt agatccagat ccattcatgg aagctttgaa tgagtatggt ttgccatggg
    32941 ttgtggttga aaatccacaa atggtggact aatgaagtta gaacaagtac caacaccagc
    33001 ctatgttatt gacttggcca agttagaagc taattgccgc attctacaat atgtacaaga
    33061 agaggccggt tgcaaggtct tgcttgccca gaaggcatat tccctctaca aaacttatcc
    33121 cttgattagc cagtatctat caggtacgac agctagtgga ctctatgagg ccaaattggc
    33181 aagggaagaa tttcctggtg aagtccatgt atttgcgcct gctttcaagg atgcagactt
    33241 ggaggaattg cttgggataa cagaccatat cgtctttaac tcagagagac agttgcgtaa
    33301 gcatggggct cgttgtcgag aggctggtgt cagtgttggt ttgcgcctca accctcagtg
    33361 ttcaactcaa ggagatcacg cgctctatga cccttgtgca ccaggttctc gctttggagt
    33421 tactatagac aagattccga gtgatttgct agatttggtt gacggacttc attttcatac
    33481 cctttgcgag cagggagcag atgatttaca aacaactttg aaagcagtag aagaacaatt
    33541 tggtccctac ttacatgagg taaaatggct caatatgggt ggtggtcatc atattacaag
    33601 agaaggttac gatgtggatt tgctgatttc agaaatcaag cgtatccgaa aaacttacaa
    33661 tcttgaaatc tatatcgagc ctggtgaagc cattgcgctt aatgcgggtt atttagcaac
    33721 tgaggtatta gatattgtag aaaacggtat ggaaatcttg gttttagacg cctctgcgac
    33781 ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca cctttgagaa atggctttga
    33841 ggcacaggaa aaagcccata cctacagact ttcttctaat acctgtctga cgggcgatgt
    33901 gattggtgat tatagttttg aaaatccagt ccaaatcgga gacagacttt attttcaaga
    33961 catggccatt tattcttttg tcaaaaataa tacctttaat ggtattggat tgccaagtct
    34021 ctatctcatg gacgaacagg gagactgtag cttactcaaa gcttttggct atcaagactt
    34081 taaagggaga ttatcatgat ggacagtcca aaaaaattag gctatcacat gccagcagag
    34141 tacgaacccc atcatggtac cctcatgata tggccgactc gaccaggatc atggcctttt
    34201 caaggaaagg ctgctaaaag atcatttact cagatcatcg agaccatagc agaaggggaa
    34261 agagtctatc ttttggtgga gcaggcctat ctatctgaag cccaatccta tcttggagac
    34321 aaggttgttt atttagacat tcccaccaat gatgcctggg cgcgtgatac tggcccaacc
    34381 attctcgtca atgataaagg taagaaatta gccgtggatt gggccttcaa tgcttgggga
    34441 ggcacctatg atggtcttta tcaagattat gaagaggatg accaagtagc cagtcgtttt
    34501 gctgaggcct tgggaaagcc tgtctatgat gctaaacctt ttgtactgga aggaggcgca
    34561 atccatagcg atggtcaagg aactattctc gtaactgaaa gttgcttgct tagtcctggt
    34621 cgcaatccta acctgactaa agaggagatt gaaaacacat tattagaaag tcttggtgct
    34681 gaaaaagtta tttggcttcc ttatggtatt tatcaggatg aaaccaatga acacgtcgat
    34741 aatgttgctg cctttgttgg tcctgctgag gttgttttag cttggacaga tgacgaaaat
    34801 gatccccagt atgccatgtc aaaagcagat ctcgaactct tagaacagga aacagatgca
    34861 aaaggttgtc acttcaccat tcataaattg cctatccctg cagttcgaca agttgtgaca
    34921 gaagaagatt tgccaggcta catctatgaa gaaggagaag aaaagcgata cgcaggtgaa
    34981 cgactagcag cttcctacgt aaacttttat atcgccaaca aggctgtctt ggttccacag
    35041 tttgaggatg taaacgacca agtggcctta gatatcctca gcaagtgttt cccagaccgt
    35101 aaagttgtcg gaataccagc cagagatatt ctcttaggtg gtggcaatat ccactgtatc
    35161 acccaacaaa ttccagaata ggagaaaaag atgagaaatg taagagttgc aaccattcag
    35221 atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg cagagcgttt agtacgtcag
    35281 gctgctgagc aaggagccca aattattctc ttgcccgagt tgtttgaaca tccctatttc
    35341 tgtcaggaac gtcagtatga ctactaccag tatgcccaat ctgtagcgga aaatactgac
    35401 attcagcatt ttaaggtgat tgctaaggaa ctacaagttg ttttaccaat cagtttctat
    35461 gaaaaagatg gtaatgtctt gtataactct attgccgtca ttgatgcaga tggggaagtg
    35521 ctgggcgttt atcgaaagac ccacatacca gatgaccatt attatcaaga aaaattctat
    35581 ttcacgcctg gtaacactgg tttcaaggtc tggaatactc gctatgctaa gattggtatc
    35641 ggtatctgtt gggatcaatg gttccctgaa acagcgcgct gtcttgcatt gaatggtgct
    35701 gaattgctct tttatcctac agctatcggt tcagagccaa ttttggatac agatagttgt
    35761 ggtcactggc aacgtactat gcaagggcac gcagcagcga atattgttcc agtcatcgca
    35821 gccaatcgtt atggtttaga ggaggttact cctagtgagg aaaatggcgg acagagttcc
    35881 agtcttgact tctacggttc ctcctttatg acggatgaaa caggagctat tctagaacga
    35941 gctgaaagac aagaagaagc tgttctgtta gctacttatg acctagacaa gggagcaagt
    36001 gaacgcctaa actggggctt gtttcgagat agaagaccag aaatgtatag acaaattaca
    36061 gattagtgtg ggagaaatga gagattcatt ctgctagact aacttcttag tagcaactat
    36121 aagatactat ggcatctagt aaatcgattt ttatgattcg ctattcttgt ctattgatta
    36181 gtccgtattt taaaatatta gcaaaaaagc aaatagcagt aacttctgtc tatttgcttt
    36241 tcttttttat agaatatatt tctcaatagc acgcgcaacg ccgtcttctt cgttgcttga
    36301 ggtaacggca tccgcaagag atttgacata atcgctggca tttcccattg caatcccaag
    36361 ccctgcaaac tggagcattt cgatatcgtt attagcatcg cccatggcca taatctctga
    36421 ggaatcaatc ttcaaaatct cagctagtcg tgaaagagca gtagcctttg tcgttccaag
    36481 cggcattgct tcataaatga caggctgcga acgaactcca ctgaatcgtt ggcaaagctc
    36541 ttcagcaaaa cgctgctcaa aatcgtctgt ttgttctttt gttcctaaaa acataccttg
    36601 gaacatccgg aactttccac tagtcgcttc ttcaagagaa atttcagtca ggtctgaaaa
    36661 tactagttta gcatcatttt caataacttg attgggtttg ccaccgagaa caaaataatg
    36721 tgactcgtca aaaagtgtca actgaacatc actcttttca gcaaggtcat agaggtattc
    36781 gatgtcagct ggactcagtt ctttccagtc aactagactc caatcactgg tctggtgagt
    36841 tgaacaaccg ttgttaacaa taatatattc gttctggagg tcgagtccca gttttttgta
    36901 gtaggggagg acaccgaaaa gggggcgacc cgtacagaga accagtttga cacctttttc
    36961 aatggctttg tgaatagcag taatgtgagc ttgtgggatt tccttggctt cattgaggag
    37021 ggtgccgtcc atatccaagg ctagtagttt aatcataggt cttccttctt tattttttgc
    37081 tattattata gcatattttg gagaagaaat tgatagaaag cttgagacta attgatttta
    37141 tagtttaaga tgttttgatg acaattcatg atttgaagag gatatttggc aaagatatgc
    37201 tatactatgt ttgtcaatgt tgcaactaga caaattaaaa aaccaactta atataatagt
    37261 ttttttgtaa gtaggtatga gtatcagatt actcaactaa tctgaagaat aatggaggaa
    37321 atatatcatg attttaatga caaaaaatat aaatctaaca aatgaagaat tagagctgat
    37381 acaaggtgga gcagatccct atggtaaaga acctaatggt tattatcctt ggcaaatgga
    37441 accagtatta actatgccgg ttcatggatt ttgtcccaga ggaaccgatg atttaggata
    37501 tattggagga ggtaatcatc tttgcaaagg aagtgctgcg agattttaag taaaatttat
    37561 taggaatatg aagaaacaag gggagaaaac agaggattta atatgaaaaa acgagctatt
    37621 caaattttac tagtattgtc cttaattttt tacaaatcaa cttggttttg gaggcttttc
    37681 aattatctcg caaagcccta tctaccagca agtcgtgaat tttttcagat tctgcttttg
    37741 atggagagtg gagttctttt attagcggtc atctatctac tggtttttgc aggaaagaaa
    37801 atttttcatt tcaagtggca gctgaggtat tttatctacc ttttactggg ttacatcact
    37861 tcgtatatgt ctgactttct cttttcgtat ttcatatctc tgtcttcaaa tcagatttct
    37921 ttgaatgaaa cggtagaaat gatggggaga caggagttcc cttatttctt gctcatcgtt
    37981 tgcttcatcg cccctattgc tgaggaattg atttatcgag gtgtgcttat gacaaccttt
    38041 ttcaaaaact caccttggta cggagatgtt ttgctttctg ctattatttt cggttatatt
    38101 catatcaatt ttgctttaac tcctcttgct tttttcattt atgctagtgg aggtcttatt
    38161 ttagctctat tgtatcgcat gactaaaaat ctctactatc caatactagt tcatattctc
    38221 atcaatatca ctgccttctg ggatgtttgg ttactcctat tttcaggaag ttagcttact
    38281 aaaaaaatgt cggaattttc cggcattttc ttttttcaca aatagtcaac gtttttcttt
    38341 ccgatactga agtggtgtgt agccacttat ttttttgaat tgattttgaa aataagattg
    38401 gcgtaagaaa ggcagatagt gaagatagtt aagaagaata ggatgttctt ttttcctttt
    38461 tggaaaactt ctaaaatatg gtataatgaa aagataaaga agttgggggt agaagatgaa
    38521 cattcaacaa ttacgctatg ttgtggctat tgccaatagt ggtacttttc gtgaagctgc
    38581 tgaaaagatg tatgttagtc agccgagtct gtctatttct gttcgtgatt tggaaaaaga
    38641 gttgggcttt aagattttcc gtcggaccag ctcagggact ttcttgaccc gtcgtgggat
    38701 ggaattttat gaaaaagcgc aagaattggt taaaggattt gatatttttc aaaatcagta
    38761 tgccaatcct gaagaagaaa aagatgaatt ttccgttgct agccagcact atgacttctt
    38821 gccaccaact attacggcct tttcagagcg ctatcctgac tataagaact tccgtatttt
    38881 tgaatcaact actgttcaaa tattagatga agtggcgcaa gggcatagtg agattgggat
    38941 tatctacctc aacaatcaaa ataaaaaggg gattatgcaa cgggttgaaa aattaggtct
    39001 ggaggtcatc gaattgattc ctttccatac ccatatttat ctccgtgagg gtcatccttt
    39061 agcccagaaa gaggaattag tcatggagga tttagcggat ttaccaacgg ttcgtttcac
    39121 tcaagagaaa gacgagtacc tttattattc agagaacttt gtcgatacca gcgctagctc
    39181 acagatgttt aatgtgacag accgtgccac cttgaatggt attttggagc ggacggacgc
    39241 ctatgcgaca ggttctggat ttttagatag tgacagtgtt aatggcatta cagttattcg
    39301 tctcaaggat aacctagata accgcatggt ctatgttaaa cgtgaagaag tggagcttag
    39361 tcaagctggg actctcttcg tagaagtcat gcaagaatat tttgatcaaa agaggaaatc
    39421 atgaaaaaaa gagcaatagt ggcagtcatt gtactgcttt taattgggct ggatcagttg
    39481 gtcaaatcct atatcgtcca gcagattcca ctgggtgaag tgcgctcctg gattcccaat
    39541 ttcgttagct tgacctacct gcaaaatcga ggtgcagcct tttctatctt acaagatcag
    39601 cagctgttat tcgctgtcat tactctggtt gtcgtgatag gtgccatttg gtatttacat
    39661 aaacacatgg aggactcatt ctggatggtc ttgggtttga ctctaataat cgcgggtggt
    39721 cttggaaact ttattgacag ggtcagtcag ggctttgttg tggatatgtt ccaccttgac
    39781 tttatcaact ttgcaatttt caatgtggca gatagctatc tgacggttgg agtgattatt
    39841 ttattgattg caatgctaaa agaggaaata aatggaaatt aaaattgaaa ctggtggtct
    39901 gcgtttggat aaggctttgt cagatttgtc agaattatca cgtagtctcg cgaatgaaca
    39961 aattaaatca ggccaggtct tggtcaatgg tcaagtcaag aaagctaaat acacagtcca
    40021 agagggtgat gtcgtcactt accatgtgcc agaaccagag gtattagagt atgtggctga
    40081 ggatcttccg ctagaaatag tctaccaaga tgaggatgtg gctgtcgtta acaaacctca
    40141 gggaatggtt gtgcacccga gtgctggtca taccagtgga accctagtca atgccctcat
    40201 gtatcatatt aaggacttgt cgggtatcaa tggggttctg cgtccaggga ttgttcaccg
    40261 tattgataag gatacgtcag gtcttctcat gattgctaaa aacgatgatg cgcatctagt
    40321 acttgcccaa gaactcaaag ataaaaagtc tctccgcaaa tattgggcga ttgttcatgg
    40381 aaatctgcct aatgatcgtg gtgtaattga agcgccgatt ggccggagtg aaaaagaccg
    40441 taagaaacag gctgtaactg ctaaagggaa gcctgcagtg acgcgttttc acgtcttgga
    40501 acgctttggc gattatagct tagtagagtt gcaactggag acagggcgta ctcatcaaat
    40561 ccgtgtccac atggcttata tcggccatcc agtcgctggt gatgaggtct atggtcctcg
    40621 caagactttg aaaggacatg gacaatttct tcatgccaag actttaggtt ttactcatcc
    40681 gagaacaggt aagaccttgg aatttaaagc agatatccca gagattttta aggaaacctt
    40741 ggagagattg agaaagtaag aatgaaaaag aaattaacta gtttagcact tgtaggcgct
    40801 tttttaggtt tgtcatggta tgggaatgtt caggctcaag aaagttcagg aaataaaatc
    40861 cactttatca atgttcaaga aggtggcagt gatgcgatta ttcttgaaag caatggacat
    40921 tttgccatgg tggatacagg agaagattat gatttcccag atggaagtga ttctcgctat
    40981 ccatggagag aaggaattga aacgtcttat aagcatgttc taacagaccg tgtctttcgt
    41041 cgtttgaagg aattgggtgt ccaaaaactt gattttattt tggtgaccca tacccacagt
    41101 gatcatattg gaaatgttga tgaattactg tctacctatc cagttgaccg agtctatctt
    41161 aaaaaatata gtgataatcg tattactaat tttgaacgtc tatgggataa tctgtacggt
    41221 tatgataagg ttttacagac tgcttcagaa aaaggtgttt cagttattca aaacatcaca
    41281 cagggagatg ctcattttca gtttggggac atggatattc aactctataa ctatgaaaat
    41341 gaaaccgatt catcaggtga attaaagaaa atttgggatg ataattccaa ttccttgatt
    41401 agtgtggtaa aagtcaatgg caagaaaatt taccttgggg gcgacttaga taatgttcat
    41461 ggagcagaag acaagtatgg tcctctcatt ggaaaagttg atttgatgaa gtttaatcat
    41521 caccatgata ccaacaaatc aaataccaag gatttcatta aaaatttgag tccgagtttg
    41581 attgttcaaa cttcggatag tctaccttgg aaaaatggtg ttgatagtga gtatgttaat
    41641 tggctcaaag aacgaggaat tgagagaatc aacgcagcca gcaaagacta tgatgcgaca
    41701 gtttttgata ttcgaaaaga cggttttgtc aatatttcaa catcctacaa gcctattcca
    41761 agttttcaag ctggttggca taagagttca tatggaaact ggtggtatca agcgcctgat
    41821 tctacaggag aatatgctgt cggttggaat gaaattaagg gtgaatggta ttactttaac
    41881 caaacgggta tcttgttaca gaatcaatgg aaaaaatgga acaatcgttg gttctatttg
    41941 acagactctg gtgttgctgc taaaaattgg aagaaaattg ttggaatctg gtattatttt
    42001 aacaaagaaa accagatgga aattggttgg attcaagata aagagcagtg gtattatttg
    42061 gatgttgatg gttctatgaa gacaggatgg cttcaatata tggggcaatg gtattacttt
    42121 gctccatcag gggaaatgaa aatgggctgg gtaaaagata aagaaacctg gtactatatg
    42181 gattctactg gtgtcatgaa gacaggtgag atagaagttg ctggacatca ttactatcta
    42241 gaagaatcag gagctatgaa gcaaggctgg cttaaaaagg caaatgattg gtatttctac
    42301 aagacagatg gttcacgagc tataggttgg attaaagaca aggataaatg gtacttcttg
    42361 aaagaaaatg gtcaattact tgtgaatggt aagacaccag aaggctatac tgtggattca
    42421 agtggtgcct ggttagtgga tgttccgatc gagaaatctg ctacaattaa aactacaagt
    42481 cattcagaaa taaaagaatc caaagaagta gtgaaaaagg atcttgaaaa taaagaaacg
    42541 agtcaacatg aaagtgttac aaattcttca actagtcaag atttgacatc ctcaacttca
    42601 caaagctctg aaacgagtgt aaacaaatcg gaatcagaac agtagtagaa aagaaggttt
    42661 tagggccttc tttttcctat caactctttt ctatttcctg ttattcatgt tataatggat
    42721 aaatatgaat aatcggagtg agactatgaa atacaaacgg attgtcttta aggtgggtac
    42781 ttcttctctg acaaatgagg atggaagttt atcacgtagt aaggtaaagg atattaccca
    42841 gcagttggct atgctgcacg aggctggtca tgagttgatt ttggtgtctt caggtgccat
    42901 tgcggctggt tttggagcct taggatttaa aaagcgtccg actaaaattg ctgataaaca
    42961 ggcttcagca gcggtagggc agggactttt gttggaagaa tatacgacca atcttctctt
    43021 gcgtcaaatc gtttctgcac aaatcttgct gacccaagat gactttgtgg ataagcgtcg
    43081 ttataaaaat gcccatcagg ctttgtcggt tttgctcaac cgtggggcaa ttcctatcat
    43141 aaatgagaat gatagtgtcg ttattgatga gctcaaggtt ggggacaatg acactctaag
    43201 tgctcaagta gcggcgatgg tccaagcaga ccttttagtt ttcttgacag atgtggacgg
    43261 tctctatact ggaaatccta attcagatcc aagagccaaa cgcttggaga gaatcgagac
    43321 catcaatcgt gagattattg atatggctgg tggagcaggt tcgtcaaacg gaactggggg
    43381 tatgttaacc aaaatcaagg ctgcaactat cgcgacggaa tcaggagttc ctgtttatat
    43441 ctgctcatcc ttgaaatcag attccatgat tgaggcggca gaggagactg aggatggttc
    43501 ttactttgtt gctcaagaga aggggcttcg tacccagaaa caatggcttg ccttctatgc
    43561 tcagagtcaa ggttctattt gggttgataa aggggctgcg gaagctctct ctcaacatgg
    43621 aaagagtctt ctcttatctg gtatcgttga agcagaagga gccttttctt acggtgatat
    43681 cgtgacagta tttgacaagg aaagtggaaa atcacttgga aaaggacgcg tgcaatttgg
    43741 agcatctgct ttggaggata tgttgcgttc tcaaaaagcc aagggtgtct tgatttaccg
    43801 tgacgactgg atttccatta ctcctgaaat ccaactactt tttacagaat tttagaggta
    43861 aactatggtg agtagacaag aacaatttga acaggtacag gctgttaaaa aatcgattaa
    43921 cacagctagt gaagaagtga aaaaccaagc cttgctagcc atggctgatc acttagtggc
    43981 tgctactgag gaaattttag cggctaatgc cctcgatatg gcagcggcta aggggaaaat
    44041 ctcagatgtg atgttggatc gtctttattt ggatgcagat cggatagaag cgatggcaag
    44101 aggaattcgt gaagtggttg ccttaccaga tccaatcggt gaagttttag aaacaagtca
    44161 gcttgaaaat ggtttggtta tcacaaaaaa acgtgtagct atgggtgtca tcggtattat
    44221 ctatgaaagc cgtccaaatg tgacgtctga tgcggctgct ttgactctta agagtggaaa
    44281 tgcggttgtt cttcgtagtg gtaaggatgc ctatcaaaca acccatgcca ttgtcacagc
    44341 cttgaagaag ggcttggaga cgactactat tcatccaaat gtgattcaac tggtggagga
    44401 tactagccgt gaaagtagtt atgctatgat gaaggccaag ggctatctag accttctcat
    44461 tcctcgtgga ggagctggct tgatcaatgc agtggttgag aatgcgattg tacctgttat
    44521 cgagacaggg actgggattg tccatgtcta tgtggataag gatgcagacg aagacaaggc
    44581 gctgtctatc atcaacaatg ctaaaaccag tcgtccttct gtttgtaatg ccatggaggt
    44641 tctgctggtt catgaaaaca aggcagtaag cttccttcct cgcttggagc aagtgttggt
    44701 tgcagatcga aaagaagctg ggttggaacc aattcaattc cgcctagata gcaaagcaag
    44761 ccagtttgtt tcaggtcaag ctgctcaagc acaagacttt gataccgagt ttttagacta
    44821 tattctagct gttaaggttg tgagcagttt agaagaagcg gttgcgcata ttgaatccca
    44881 cagtacccat cattcggatg ccattgtgac ggaaaatgct gaagctgcag catactttac
    44941 agatcaagtg gactctgcag cggtgtatgt taatgcctca actcgtttca cagatggagg
    45001 acaatttggt cttggttgtg aaatggggat ttctactcag aaattgcacg cgcgtggtcc
    45061 tatgggcttg aaggaattga ctagctacaa gtatgtggtc actggtgatg gacagataag
    45121 ggagtaagag atgaagattg gatttatcgg tttggggaat atgggtgcta gtttagccaa
    45181 gtctgtcttg caggctagac cgtcagatga gattctcctt gccaatcgta gtcaagtcaa
    45241 ggtggatgct ttcatcgcta acttcggtgg tcagacttct aacaatgaag aaatattcga
    45301 agaagcagat gtgatttttc taggtgttaa gcctgctcag ttttctgaac tgctttctca
    45361 ataccagacc atccttgaaa aaagagaaag tcttcttttg atttcgatgg cagctggatt
    45421 gatcttagaa aaactagcaa gtcttatccc aagccaacac cgaattattc gtatgatgcc
    45481 taatacccct gcttctatcg ggcaaggagt gattagttat gccttgtctc ctaattgcag
    45541 ggctgaggac agtgagctct tttgtcagct tttatccaag gctggtctct tggttgaatt
    45601 aggagaaagt ttaatcaatg cagcgacagg tcttgcaggc tgtggaccag cctttgtcta
    45661 tctctttatt gaggccttgg cagatgcagg tgttcagacg ggattaccac gagaaacagc
    45721 cttgaaaatg gcagcccaaa ctgtggtagg agctgggcaa ttggtcctag aaagccagca
    45781 acatcctgga gttttgaaag atcaagtttg tagtccaggc ggttcgacta ttgctggcgt
    45841 agcaagccta gaagcgcatg cttttcgagg aacggtcatg gaggcagttc atcaagccta
    45901 taaacgaaca caagaactag gtaaataaga ggtagtttta tctgcctctt ttatggtggt
    45961 tgatactctt cgaaaatcaa attcaaactg cgtcagcttc accttgccgt actcaagtac
    46021 agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtatgaa atgagaagac
    46081 aaaaagattg tcacaaaccc ctattttttt gatagaatag aagtagtaaa aaagaaatga
    46141 gttagacatg tcaaaaggat ttttagtctc tcttgaggga ccagagggag caggcaagac
    46201 cagtgtttta gaggctctgc taccaatttt agaggaaaaa ggagtaaagg tgctgacgac
    46261 ccgtgaacct ggcggagtct tgattgggga gaagattcgg gaagtgattt tggatccaag
    46321 tcatactcag atggatgcta aaacagagct acttctctat attgccagtc gcagacagca
    46381 tttggtggaa aaagttcttc cagcccttga agctggcaag ttggtcatca tggatcgttt
    46441 tatcgatagt tctgttgcct atcagggatt tggtcgtggc ttagatattg aagccattga
    46501 ctggctcaat cagtttgcga cagatggcct caaacccgat ttgacactct attttgacat
    46561 cgaggtggaa gaagggctgg ctcgcattgc tgcgaatagt gaccgcgagg tcaatcgtct
    46621 ggacttggaa ggtttggaat tgcacaagaa agtccgtcaa ggctaccttt ctctcctgga
    46681 aaaagaagga aatcgcattg tcaagattga tgctagtctc cctttggagc aagttgtgga
    46741 aactaccaag gctgtcttgt ttgacggaat ggacttggcc aaatgaaaca agatcaacta
    46801 aaggcttggc aaccagctca gtttgaccgt tttgtccgta tcttagaaca agaccagctc
    46861 aatcacgcct atctcttttc aggtttcttt ggaagcttgg aaatggcgca atttttagct
    46921 aagagcctct tttgtacgga taaagttggc gtcttaccat gtgagaaatg ccgaagttgc
    46981 aagctgattg aacaggaaga gtttccagat gtcaccttga ttaagccagt caatcaggtc
    47041 atcaagacag aacgcattcg ggaattggtg ggacagtttt ctcaagcagg gattgaaagc
    47101 cagcaacagg tctttattat cgagcaagcg gataaaatgc atcccaacgc agccaattct
    47161 ctgctcaagg tcatcgaaga accccagagt gaagtttata ttttcttctt gactagcgat
    47221 gaggaaaaga tgttaccgac aatccgaagt cggactcaga tcttccactt taaaaagcaa
    47281 gaagaaaaac ttatcttact cttagaacaa atgggacttg ttaagaaaaa agcgactctt
    47341 ttagctaagt ttagtcaatc gcgagctgaa gcagaaaagt tggcacatca ggcaagtttt
    47401 tggaccttgg tcgatgaaag tgaacgcctg ctgacttggt tagtagctaa gaaaaaagaa
    47461 agttatctac aggttgccaa attagccaac ttggcagatg ataaggaaaa acaggatcag
    47521 gttttacgga ttcttgaagt tctctgtggg caggacctct tgcaggtaag agtaagagtg
    47581 attctacaag atttactaga agctagaaaa atgtggcaag ctaatgtcag ctttcaaaat
    47641 gccatggaat atctggtctt gaaagaaata taaactcaaa aatgaatgat aaagaaagga
    47701 aagggctgtt ttatggacaa aaaagaatta tttgacgcgc tggatgattt ttcccaacag
    47761 ttattggtaa ccttggccga tgtggaagcc atcaagaaaa atctcaagag cctggtagag
    47821 gaaaatacag ctcttcgttt ggaaaattct aagttgcgag aacgcttggg tgaggtggaa
    47881 gcagatgctc ctgtcaaggc caagcatgtt cgtgaaagtg tccgtcgcat ttaccgtgat
    47941 ggatttcacg tatgtaatga tttttatgga caacgtcgag agcaggacga ggaatgtatg
    48001 ttttgtgacg agttgctata cagggagtag gcatgcagat tcaaaaaagt tttaaggggc
    48061 agtctcccta tggcaagctg tatctagtgg caacgccgat tggcaatcta gatgatatga
    48121 cttttcgtgc tatccagacc ttgaaagaag tggactggat tgctgctgag gatacgcgca
    48181 atacagggct tttgctcaag cattttgaca tttccaccaa gcagatcagt tttcatgagc
    48241 acaatgccaa ggaaaaaatt cctgatttga ttggtttctt gaaagcaggg caaagtattg
    48301 ctcaggtctc tgatgccggt ttgcctagca tttcagaccc tggtcatgat ttagttaagg
    48361 cagctattga ggaagaaatt gcagttgtga cagttccagg tgcctctgca ggaatttctg
    48421 ccttgattgc cagtggttta gcgccacagc cacatatctt ttacggtttt ttaccgagaa
    48481 aatcaggtca gcagaagcaa ttttttggct tgaaaaaaga ttatcctgaa acacagattt
    48541 tttatgaatc acctcatcgt gtagcagaca cgttggaaaa tatgttagaa gtctacggtg
    48601 accgctccgt tgtcttggtc agggaattga ccaaaatcta tgaagaatac caacgaggta
    48661 ctatctctga gttattagaa agcattgctg aaacgccact caagggcgaa tgtcttctca
    48721 ttgttgaggg tgccagtcag ggtgtggagg aaaaggacga ggaagacttg ttcgtagaaa
    48781 ttcaaacccg catccagcaa ggtgtgaaga aaaaccaagc tatcaaggaa gtcgctaaga
    48841 tttaccagtg gaataaaagt cagctctacg ctgcctacca cgactgggaa gaaaaacaat
    48901 aaagggagac aggatgtaat aattctgtct gtttctgttt aacttaatta gtgatgataa
    48961 tataaagatg tatcacttgg tatagaagct ttggtattaa gttttttatt aagcccatac
    49021 ggaataccga tggttggagc agcagttata gcgttcttag aaggtataaa tagaaaaata
    49081 aggtcatttt aaatcaaagg attgataaat cagaaagaag gtgatttttt gcgaacatac
    49141 gaaaataaag aagaactaaa agctgagata gagaaaacat ttgagaaata tattttagaa
    49201 tttgataata ttccagaaaa tttaaaagat aagagagctg atgaagttga cagaactcca
    49261 gcagaaaacc ttgcttatca ggttggttgg accaacttgg ttcttaaatg ggaagaagat
    49321 gaaagaaagg ggcttcaagt aaaaacacca tcggataaat ttaaatggaa tcaacttggt
    49381 gaattatatc agtggttcac agatacctac gctcatttat ctctgcaaga gttgaaagca
    49441 aaattaaatg aaaatattca ttctatctct gcaatgattg attcgttgag tgaggaagaa
    49501 ttatttgaac cgcatatgag aaagtgggct gatgaagcga ctaaaacagc gacttgggaa
    49561 gtgtataagt ttattcatgt aaatacggtt gcaccttttg gaactttcag aactaaaatc
    49621 agaaaatgga agaagatagt attataaatt atatttttaa ctttaaaaaa tttcataaaa
    49681 atggttacca aaggcgatag aagaaaaact atcgtctttt tctttgcaaa tttttaagaa
    49741 gggaggtgat cttgcatgga ctttgaatat ttttataaca gagaagcgga aagatttaac
    49801 ttcttaaaag taccggagat attagttgat agagaagaat ttcggggctt atcagcagaa
    49861 gcaattatcc tttattccat acttcttaaa cagacaggaa tgtcatttaa gaataactgg
    49921 atagacaagg aaggcagagt atttatctat tttactgtcg aagaaattat gaaaagaaga
    49981 aatatctcaa agccaactgc cataaaaaca ttagatgagc ttgatgtaaa aaaaggaata
    50041 ggactgatcg aaagagtaag gcttggactt ggtaagccga acatcattta tgttaaagac
    50101 tttatgagta tatttcaggt aaaagaaaat gacttacaga agtcaaaaaa cttaacttca
    50161 gaagtaaaag attttaacct cagaagtaaa gaaaatgaac ttcaagaggt taagaacctt
    50221 gactctaact atatagagaa taataagagt aagtatagta agagagaata tagttttggt
    50281 gaaaacggac ttggaacatt tcaaaatgtg tttttagctg ctgaagatat atcggattta
    50341 caaatcataa tgaactcaca gcttgagaat tacattagac ttcctgcaaa aatagaatcc
    50401 tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaagc gtttacgatg
    50461 attttgatag gttgttgaaa acattttaaa cgtttttact ttggcaaaga tgttctcaac
    50521 cttgcttctc tccttagata gcgcatggtt acaggcttta tcttcaactg ttagcggctt
    50581 gagtttgctg gatttacgtg aagtttgtgc ttgaggatat atcttcatga gcccttgata
    50641 accactgtca gccaagattt taccagcttg tccgatattt ctgcgactca ttttgaacaa
    50701 cttcatatca tgacaatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt
    50761 gacaatcgct tgagtcttca tagcgtgaaa tttcttttta ccagaatcat tcgctaattc
    50821 ttttttttag ggcgattgat ttttacttcc gtcgcatcaa tcattaccgt gtcctcagag
    50881 ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa gagttacttc aacccattgg
    50941 ctccgacgga gtaagttgct ttcgtgaata ccaaaatcag ccgcaatttc ttcataagtt
    51001 cgatattctc gcacatattg aagagtagcc ataagaaggt cttctaggct taatttaggt
    51061 tttcgtccac cttttgcgtg tttaagttga taagctgttt ttaatacagc taacatctct
    51121 tcaaaagtcg tgcgctgaac accaacaaaa cgcttaaatc gtgcatcagt tagttgttta
    51181 cttgcttcat cattcataga actactatac catattttgt ttcgcaggaa gtctattgga
    51241 aagtaagaaa tattgaagct gaggctatta gaagaaattg tgagcgtggt gctatttttt
    51301 caggtaaaat aaaatatcac gaagattcac agtttaaagg agatcactat gttgaatgtt
    51361 atgctgtttt agataatacg gttatagcaa gagatagaat aacagtccct atcgatccgt
    51421 tatgtggaaa agattttata gagtagcata taattgattc ttaactggaa tactcactat
    51481 ctctttacat caagaaaatg actaaacagg gaagtttgcc ttcttccctt tttttgttat
    51541 actagtagaa gaaaaaatag aaagatttgt gggagtgaaa aagtcctgtg gactttttca
    51601 gcctgagcca agaaactcga aagctcgtaa gtctgattgg ctttttcaat gtgaatctta
    51661 acttcacact cccaaagagg tattagtgtc gtgtctcaat cttatatcaa tgttatcggt
    51721 gctggtttgg caggttctga agcagcttac caaatcgcag agcgtggtat tccagttaaa
    51781 ctttatgaaa tgcgtggtgt caagtcgact cctcagcaca aaacagacaa ttttgctgag
    51841 ttggtttgtt ccaattcttt gcgtggggat gctttgacaa atgcagttgg tcttctcaag
    51901 gaagaaatgc gtcgcttggg ttctgttatc ttggaatctg ctgaggctac acgtgttcct
    51961 gccggtggag cccttgcggt ggatcgtgat ggtttctctc aaatggtgac cgaaaaagtg
    52021 gtcaaccacc ccttgattga agtggtgcgt gatgaaatta cagaattgcc aacagatgtt
    52081 attacagttg tggcgactgg tcccttgact agcgatgccc tggctgaaaa gattcatgcc
    52141 cttaataatg gcgatggctt ctatttctac gatgcagcag cgcctattat cgatgtcaac
    52201 actatcgata tgagtaaggt ctatctcaaa tctcgttatg ataagggaga agcagcctat
    52261 ctcaatgctc caatgaccaa gcaagagttt atggatttcc atgaagcctt ggtcaatgcg
    52321 gaagaagcac cgctcaattc ttttgaaaaa gaaaagtact ttgaaggatg tatgccaatc
    52381 gaagttatgg ccaaacgtgg cattaaaact atgctttatg gccctatgaa gccagtcggt
    52441 cttgagtatc cggacgacta cacaggacct cgtgatggag aatttaaaac accttatgcg
    52501 gttgtgcaac ttcgtcagga taatgcagct ggtagcctat acaatattgt tggtttccag
    52561 acccacctca aatggggaga acaaaagcgt gtcttccaaa tgattccggg tcttgaaaat
    52621 gcggagtttg tccgttatgg tgtcatgcat cgcaattctt acatggattc accaaatctt
    52681 cttgagcaga cttaccgttc caagaaacaa ccaaatctct tctttgctgg tcagatgacg
    52741 ggggtggaag gctatgttga gtcggcggct tcgggcttag ttgcgggaat taacgcagct
    52801 cgtctcttca aggaagaaag cgaggttatt ttccccgaga cgacagcgat tggaagctta
    52861 gctcattaca ttacccatgc cgacagcaaa catttccaac caatgaatgt caattttggg
    52921 atcatcaagg agttggaagg cgagcgtatc cgtgataaga aggctcgtta tgaaaaaatt
    52981 gcagagcgtg cccttgccga cttagaggaa tttttgactg tctaattttt ttgaaagaat
    53041 tgttcatgat actataaaaa tcttagaaat tgtgataaaa taggtaggat gaaagaagga
    53101 gagtgaaaat ggcgaatccc aagtataaac gtattttaat caagttatca ggtgaagccc
    53161 ttgccggtga acgtggcgta gggattgata tccaaacagt tcaaacaatc gcaaaagaga
    53221 ttcaagaagt tcatagctta ggtatcgaaa ttgcccttgt tattggtgga ggaaatctct
    53281 ggcgtggaga acctgcagca gaagcaggta tggaccgtgt tcaggcagat tacactggaa
    53341 tgcttgggac tgttatgaat gctcttgtga tggcagattc attgcaacaa gttggggttg
    53401 atacgcgtgt acaaacagct attgccatgc aacaagtggc agagccttat gtccgtggac
    53461 gtgcccttcg tcaccttgaa aaaggccgta tcgttatctt tggtgctgga attggttcac
    53521 catacttctc gacagataca acagcggctc ttcgcgcagc tgaaatcgaa gcagatgcca
    53581 tcctcatggc taaaaatggc gtcgatggtg tgtacaatgc tgatcctaag aaggacaaga
    53641 cagccgttaa gtttgaagaa ttgacccacc gtgatgttat caacaaaggt cttcgtatca
    53701 tggactcaac agcttcaacc ctctcaatgg ataacgacat tgacttggtt gtcttcaaca
    53761 tgaaccaacc aggaaacatc aaacgtgtcg tatttggtga aaatatcgga acaacagttt
    53821 caaataatat cgaagaaaag gaataagaaa gaatatggct aacgtaatta ttgaaaaagc
    53881 taaagagaga atgacccagt ctcaccaatc acttgctcgt gaatttggtg gtatccgtgc
    53941 tggtcgtgcc aatgcaagct tgcttgaccg tatacatgta gaatactatg gagtcgaaac
    54001 tcctcttaac caaatcgctt caattacgat tccagaagcg cgtgttttgt tggtaacacc
    54061 atttgacaag tcttcattga aagacatcga acgtgccttg aacgcttctg atcttggtat
    54121 cacaccggct aatgacggtt ctgtgattcg cttggttatc ccagctctta cagaagaaac
    54181 tcgtcgtgac cttgctaaag aagtgaagaa ggtcggcgaa aatgctaaag tggctgttcg
    54241 caatatccgt cgcgatgcta tggacgaagc taagaaacaa gaaaaagcaa aagaaatcac
    54301 tgaagacgaa ttgaagactc ttgaaaaaga cattcaaaaa gtaacagacg atgctgttaa
    54361 acacatcgac gacatgactg ctaacaaaga gaaagaactt ttggaagtct aaaaataaac
    54421 agaaaaactc agttggcatt gctggctgag ttttattcga aagaaggaaa tatgaataca
    54481 aatcttgcaa gttttatcgt tggactgatc atcgatgaaa atgaccgttt ttactttgtg
    54541 caaaaggatg gtcaaaccta tgctcttgct aaggaagaag gtcaacatac agtaggggat
    54601 acggtcaaag gttttgcata cacggatatg aagcaaaaac tccgcctgac aaccttagaa
    54661 gtgactgcca ctcaggacca atttggttgg ggacgtgtca cagaggttcg taaggatttg
    54721 ggtgtctttg tggatacagg ccttcctgac aaggaaatcg ttgtgtcact cgatattctc
    54781 cctgagctca aggaactctg gcctaagaag ggcgaccaac tctacatccg tcttgaagtg
    54841 gataagaaag accgtatctg gggcctcttg gcttatcaag aagacttcca acgtcttgct
    54901 cgtcctgctt acaacaacat gcagaaccaa aactggccag ccattgttta ccgtctcaag
    54961 ctgtcaggaa cttttgttta cctaccagaa aataatatgc ttggttttat tcatcctagc
    55021 gagcgttacg cagagccacg tttggggcaa gtattagatg cgcgcgttat tggtttccgt
    55081 gaagtggacc gcactctgaa cctctccctc aaaccacgct cctttgaaat gttggaaaac
    55141 gatgctcaga tgattttgac ttatttggaa agtaatggcg gtttcatgac cttaaatgat
    55201 aagtcatctc cagacgacat caaggcaacc tttggcattt ctaaaggtca gttcaagaaa
    55261 gctttaggtg gtcttatgaa ggctggtaaa atcaagcagg accagtttgg gacagagttg
    55321 atttagggag gcttatgaga aaatcatttt acacttggct catgaccgag cgcaatccta
    55381 aaagtaacag tcccaaagca attttggcag acctcgcttt tgaagaggca gcttttccaa
    55441 aacatacaga tgattttgat gaggtcagtc gctttttgga ggagcatgcc agtttctctt
    55501 ttaacctagg agattttgat agcatttggc aggaatatct agaacactag catttattca
    55561 ttgggtttgg gctagtaatt tctccatccc tctgctataa taaaaagaaa taaaaggatt
    55621 agagaggttc tttatttgaa ggaacattca atagacattc aactgagtca tccagatgac
    55681 ctgtttcatc tttttggttc caatgaacgc catcttcgtt tgatggaaga agagcttgat
    55741 gttgtgattc atgctcgtac ggagattgtc caggttttgg gagaagagtc tgcctgtgag
    55801 gaagcccgtc aagttattca ggctttgatg gtcttggtaa atcgtgggat gaccgttggt
    55861 acgccagatg tagtcactgc gattagcatg gtcaaaaatg atgaaattga caagtttgtc
    55921 gccctttacg aagaagaaat tatcaaagat aatactggga aacctatccg tgtcaaaacc
    55981 ctagggcaaa agctttatgt ggacagtgtc aaacagcatg atgtgacctt tggaattggg
    56041 ccagcaggta cagggaagac cttccttgca gtgaccttgg cagtgactgc ccttaaacgt
    56101 gggcaagtca agcgaattat cctaactcgt ccagcggtgg aagcgggaga gagtcttgga
    56161 tttcttccgg gtgatcttaa ggagaaggtg gatccttacc ttcgtcctgt ttacgatgcc
    56221 ttgtatcaaa ttcttgggaa agaccaaacg actcgtctca tggagcgtga aattatcgaa
    56281 attgcgcccc ttgcctatat gcgtggccgg accttggatg atgcctttgt cattctcgat
    56341 gaggcgcaaa acacgaccat catgcagatg aagatgttct tgacgcgttt aggctttcat
    56401 tctaagatga ttgtcaatgg agatatcagt cagattgacc tgccacgtaa tgtcaagtcc
    56461 ggtttgattg atgctcaaga gaaactcaag aacatccatc agattgactt tgttcatttt
    56521 tcagccaagg atgtggttcg ccatccagtt gtcgctcaga ttatccgagc ctatgaatat
    56581 tctactgaag ttgcacacga ctgattttga ggaagttcgc ctgcaaaaga atatactttt
    56641 gagagaggaa aatccagttg tataggctaa aggttttatc caaaggtctg agacaacgat
    56701 taggcacgat ggaaagaact tttatgtggc tgatgacgat cagtgcatct tcctgtgtca
    56761 taatcacagg gcacaagaaa gtaggaattt gaaaagatga ttgaccaact atctaagtat
    56821 tacagttgta ggatactaac tgaaaaggat attccaagta ttttatcttt atatgaaagt
    56881 aatcctctgt attttcagca ttgtccacca gaaccaaatt ttgcaactgt aaaagaggac
    56941 atgctttgtc tacctgaagg taaagctaag gctgataagt tttttgttgg attttggaat
    57001 ggatctgacc ttgtggctgt tatggatttt gtctatgcat atcctgatga ggagactgtt
    57061 tttattggtt tgtttatggt tgatcaagcc tatcagagga aagggattgg tagtcatatt
    57121 gtgacagaag cactagctta ttttgctaag aactttcgaa aggcacgttt ggcttatgtt
    57181 aagggaaatc cgcaatctca gcatttttgg gaaaagcagg gctttaaatc aattggatgc
    57241 gaggttaagc aagaactcta tacggttgtt atcgttgaac agagcctaga agattagaaa
    57301 tggcatcaag taagaactat ttggaatttg ttttggaaca attatcagga ttagatgatg
    57361 tgacttaccg ttccatgatg ggggagtata ttctttactt ccgcggcaag attattggcg
    57421 gtatttatga cgatcgcttt tagttaaacc cgtgcaagca gtcttagata agattgacca
    57481 atcttctttt gagtttccat acaaaggtgc caaagaaatg atttgagtgg aagaacttga
    57541 taataagatg tttctataag acctgatttt agctatgtat aaccaactgc caacgcccaa
    57601 acctaaaaag aaaaagcaag ggtgaacgaa gtaaaaaaga agtctgctaa ggccctgtct
    57661 ttgcacgggt aaaattttat atataaaaag aagctgggac taaagagctc agcttccttt
    57721 ggtttatata attgtcatta caagacgaag tggttgggcg aaactctgtt gactttattc
    57781 aatttagagt ttcttatgca caattgagtc tggaacgaaa gtctccagtt gcaaagtcta
    57841 cagtacaata aaccaacgat gtaatagctg atgacacaaa gcacagtggg taggacttgc
    57901 gaagtcaccc ttttcttttc aaaatttata ctaaatcatt gatatcagtg tagtcacgat
    57961 taagtccttg agcaactggt aggctagtca agtaaccttg ataagtggtc acaccttgac
    58021 gcaagccttc atcttcagag attgcttgtg cgaatccttt gccagccaaa gcttcgatat
    58081 aaggaagagt gacattggtt agggcgatgg ttgaagtgcg ggcaaccgca ccagggatat
    58141 tggcaacggc atagtggaga acaccgtgtt tttcatagac gggttcatcg tgcgttgtca
    58201 cacggtcagc tgtttcgata aggccacctt ggtcaacagc aacgtcaacg atacagagcc
    58261 tggacgcatt tgtttgacca tctcatctgt caccaattcc ggtgcttttg caccagggat
    58321 gagaatggct ccaatcacca catcagcatc tctcacactt gcttcaatgt tgaatgaatt
    58381 agatataaga gtttgaattt gacttccaaa gacttcttct agaactgaga gacgcttggc
    58441 actaatatct aaaatagtca cttgagcacc aagaccaagg gcgatgcggg cagcatgtgt
    58501 accgacgaca ccatcaccga tgatagttac ttttcctttt ggaacacctg gtacaccacc
    58561 aggtagaaca ccagagccac cagcttgctt agtaaggaag tgagctccga tttaaacagc
    58621 catacgacct gcaacctcac tcataggaac gaggagcggt agttgtcctt gattgtcacg
    58681 aacagtttca taggcaattc ctgttgtttt tgctgctaac atagcatctg ctaattctgg
    58741 agcagcggcc atgtgcaagt aggtgaagag aagaagatcg tcgcgcaagt aaccgtattc
    58801 agaacttaaa ggttctttta ctttcacaac caactctgct gcccaagctt caccagcagt
    58861 agcgacaatc tcagctcctt gcttttgata gtcagcatca gtaaagccag aaccgagacc
    58921 agcatttgtt tcgataagga cacgatgacc acgactaact aagctatgaa cacctgcagg
    58981 tgtgagggcg acacggtttt cgttattttt aatttctttt gggattccga ttaacattga
    59041 gataacctac ctttcaattg acggtcttgt tttggttgtc acattccagt tcataaatca
    59101 aaaatgtgac ggtttcattg tatatgaaac cgcttcaaaa atcaagaaaa acttgtcatc
    59161 caaatttttt atgctagact agtgaaaatc aagctttgat tggttggaaa cgtatggaat
    59221 caatatttgt gaaatttgcc cagtatccgt ctatagaaac ggagcgttta ttgcttagac
    59281 ctgtaacttt ggatgatgcg gaagcaatgt ttgactatgc ctcggacaag ggtaatacac
    59341 gttacacttt tccaaccaat caaagcttgg aagaaaccaa gaataacatt gctcagttct
    59401 atttggctaa tcccttggga cgttggggaa tagaactaaa aagcaatggt cagtttattg
    59461 gaaccattga cttgcacaag attgattctg ttcttaagaa ggcagctatt ggctacatta
    59521 tcaataaaaa gtattggaat caaggattaa cgacagaagc caatcgtgct gtgattgagc
    59581 tagcttttga gaagataggg atgaataagt tgactgccct tcacgataag gacaatcctg
    59641 cgtcaggaaa ggtcatggag aaatcaggca tgcgtttttc ccatgcagaa ccatatgctt
    59701 gtatggacca gcatgaaaaa gatcgaatcg ttacaagagt tcattatgtc ttgaccaagg
    59761 aagactattt tgcaaataaa taagcagttg aaaagaaatt tttcgactgt tttttcttcc
    59821 tcttacgaat aatctaagag aggagaaaat atggaagcaa ttatcgagaa aatcaaagag
    59881 tataaaatca tcgtcatctg tactggtctg ggcttgcttg taggcggatt tttcctgcta
    59941 aagccagctc cacaaacacc tgtaaaggaa acgaatttgc aggctgaagt tgcagctgtt
    60001 tccaaggatt tggtatccga aaaggaagtg aacaaggaag agaaggaaga accagttgaa
    60061 caagatctaa tcacagtaga tgtcaaaggt gctgtcaaat cgccagggat ttatgacttg
    60121 cctgtaggta gtcgagtcaa tgatgctgtt cagaaggctg gtggcttgac agagcaagca
    60181 gacagcaagt cgctcaatct agctcagaaa gttagtgatg aggctctggt ttacgttcct
    60241 actaagggag aagaagcagt tagtcaacag actggttcgg ggacagcttc ttcaataagc
    60301 aaggaaaaga aggtcaatct caacaaggcc agtctggaag aactcaagca ggtcaaggga
    60361 ctgggaggaa aacgagctca ggacattatc gaccatcgtg aggcaaatgg caagttcaag
    60421 tcagtagacg agctcaagaa ggtctctggc attggtggca aaacaataga aaagcttaaa
    60481 gactatgtta cagtggatta agaatttctc tattccccta atttacctga gttttctatt
    60541 actttggctt tattacgcta ttttctcagc atcttatctt gctttgttgg gctttgtttt
    60601 tctgctagtc tgtctcttta tccaatttcc gtggaaatct gctggtaaag ttctaataat
    60661 ttgcggaatc tttggatttt ggtttgtttt tcaaaattgg caacagagtc aagcgagtca
    60721 aaatctggcg gattctgttg aaagggtacg gattttgcct gatactatta aggttaatgg
    60781 tgatagtcta tcctttcgtg gcaagtctaa cggtcgtgct ttccaagtct attataaact
    60841 ccagtccgag gaggagaaag aagcctttca agctttaacc gacctgcatg agataggact
    60901 agaagggaag ctttcggagc cagaagggca gagaaatttt ggtggcttta attaccaagc
    60961 ctatctgaag actcagggaa tttaccagac tctcaatatc aaaacaatcc agtcacttca
    61021 aaagattggc agttgggata taggagaaaa cttgtccagt ttacgtcgaa aggctgtggt
    61081 ttggattaag acgcactttc cagaccctat gcgcaattac atgacaggac tcttgctggg
    61141 acatctggac accgactttg aggagatgaa tgagctttat tccagtctag gaattatcca
    61201 cctctttgcc ctatctggta tgcaggtagg ttttttcatg aatggattta agaaacttct
    61261 cttgcgattg ggcttgaccc aagaaaagtt gaaatggctg acttatccct tttcccttat
    61321 ctatgcggga ctaactggat tttcagcatc ggttattcgc agtctcttgc aaaagctact
    61381 ggctcaacat ggggttaagg gcttggataa ttttgccttg acggtgcttg tcctctttat
    61441 tgtcatgcca aactttttct tgacagcagg aggagtcttg tcctgcgctt atgcttttat
    61501 cctgaccatg accagcaaag aaggggaggg gctcaaggct gttactagtg aaagtctagt
    61561 catctccttg ggcatattgc ccattctatc cttctatttt gcggaatttc aaccttggtc
    61621 tatccttttg acctttgtct tttcctttct atttgacttg accttcttac cgctcttgtc
    61681 tattttattt gtcctttcct ttctctatcc agtcattcag ctgaacttta tctttgaatg
    61741 gttggagggc attattcgct tggtgtcaca ggtgacaagt agacctctgg tctttggaca
    61801 acccaatgca tggtttttaa tcctattgtt aatttccttg gctttggtct atgatttgag
    61861 aaaaaacatt aaaaagctaa cggtattgtg cttattgatt acagggctct ttctcctgac
    61921 caagcatcca ctggaaaatg aaatcaccat gctggatgtg gggcaaggag aaagtatttt
    61981 cctacgggat gtaactggga aaaccattct catagatgta ggtggtaagg cagaatctta
    62041 taagaaaatc gaaaaatggc aagaaaagat gacgaccagc aatgcccagc gaaccttgat
    62101 tccctatctc aaaagtcgag gagtagctaa gattgaccag ctaattttga ctaacacgga
    62161 caaggagaat gttggagatt tgtcagaggt gaccaaggct ttccatgtag gggagattct
    62221 agtatcaaaa gacagtctga aacagaagga atttgtggca gaactacaga cgactcaaac
    62281 aaaggtgcgt agtatgacag taggggagaa cttgcccatt tttggaagtc agttagaagt
    62341 tctatctcca aggaaaatgg gagatggagg acacgatgac accctagttc tgtatgggaa
    62401 attcttggat aagcaatttc tcttcacggg aaatttggag gagaaaggag agaaggactt
    62461 gctgaagcac tatccagact tgaaagtaaa tgttttgaaa gctagccaac atggcaataa
    62521 aaaatcatca agtccagcct ttctagaaaa actcaaacca gagcttactc ttatctcagt
    62581 tggaaagagc aatcgaatga aactccccca tcaggaaaca ttgacacgac tggaaggtat
    62641 caatagcaaa gtttatcgaa ctgaccagca aggagctata cgttttaagg ggttggatag
    62701 ttggaaaatc gaaagtgttc gataggaagg ataaatgttg tagattagtg aaataaacta
    62761 aaaatttgtt gcataataat gataaaaatg gtataatgaa aacgtattca atattgagga
    62821 tataaaatca ttaaaaatca gcaaaagttg ttttattagt tagtttataa tctattggtc
    62881 ttcttcagtc cagtgtatct gctgtgacag ccactaaaag ttacaagtat gattggaata
    62941 cggttttgga atatagtacc aactatcacg accatcagta tgcttggatt ccggaatggt
    63001 ctcgttatta cagctattct gagtataaag ttggcggagg ctggaactac gctcgttatg
    63061 aggtcataaa ctactatact ggaggttatt aatccttaaa gagtgagaaa aggagggctg
    63121 gatatgttaa atcttactca tgttacctta aaaacgcgac aagtcatctt gcaagatgcg
    63181 gattttacct ttaaaaaggg taggatttat ggccttcttg ctatcaatgg ctcgggaaag
    63241 acgacactat tccgagctat gagcaagttg cttcccctta gtagtggaca catcgcagtt
    63301 cctccttctt tgttttatta tgagagcgtt gaatggctgg atggaaactt aagtgggatg
    63361 gactaccttc gtctcataaa aaacatctgg aagtcagacc taaacttgag agatgaaatc
    63421 gcctactggg aaatggctga ctatatcagt cttcccatcc gcaagtattc cttagggatg
    63481 aagcaacgct tggtgattgc tatgtatttt ctcagtcagg ccaaatgctg gctcatggat
    63541 gagattacaa atggcttaga cgagtattat cgacagaagt tttttgatag gctagcacaa
    63601 atcgatagac aagaacagct ggttctttta agttcccact ataaggaaga gttggttgat
    63661 atctgcgata gagtagtaac cattcatcag gggcagatag aagaggttta gtttatgaaa
    63721 gatgttagtc tatttttatt gaaaaaagtt ttcaaaagtc gtttaaactg gattatctta
    63781 cttttatttg catctgtact cggtgttacc ttttatttaa atagtcagac tgcaaactca
    63841 cacagcttgg agagcaggtt ggaaagtcgc attgcagcca acgagagggc tatcaatgaa
    63901 aatgaagaga aactctccca aatgtctgat accagctcgg aggaatacca gtttgctaaa
    63961 aataatttag acgtgcaaaa aaatcttttg acgcgaaaga cagaaattct aactttacta
    64021 aaagaagggc gctggaaaga agcctactat ctgcagtggc aagatgaaga gaagaattat
    64081 gaatttgtat caaatgaccc gactgctagc tctggcttaa aaatgggggt tgaccgcgaa
    64141 cggaagattt accaagccct gtatcccttg aacataaaag cacatacttt ggagtttccg
    64201 acccacggga ttgatcagat tgtctggatt ttagaggtta tcatcccaag cttgtttgtg
    64261 gttgcgatta tttttatgct aacacaacta tttgcagaaa gatatcaaaa tcatctggac
    64321 acagctcact tatatcctgt ttcaaaagtg acatttgcaa tatcctctct tggagttgga
    64381 gtgggatatg taactgtgct gtttatcgga atctgtggct tttcttttct agtgggaagt
    64441 ctgataagtg gttttggaca gttagattat ccctacccaa tttatagctt agtgaatcaa
    64501 gaagtaacta ttgggaaaat acaagatgta ttatttcctg gcttgctctt agctttctta
    64561 gcctttatcg tcattgtgga agttgtgtac ttgattgctt actttttcaa gcaaaaaatg
    64621 cctgtcctct ttctttcact cattgggatt gttggtttat tgtttggcat ccaaaccatt
    64681 cagcctcttc aaaggattgc acatctgatt ccctttactt acttgcgttc agtggagatt
    64741 ttatctggaa gattacctaa gcaaattgat aatgtcaatc taaattggag catggggatg
    64801 gtcttgcttc cttgcctgat tatccttttg ttagtgggga ttctatttat cgaaagctgg
    64861 ggaagtttac gtaaaaagga agtttttaaa gtttagtttt cctataggga agctaaagaa
    64921 aaactaacat agggagagaa tcaacttggt tctctctttt tgattcgaaa accaaaccaa
    64981 aatacaaaca caaacttttc aaaaaataac tttttatctt gacaagagct agaaaacttg
    65041 gtatcatata aaagttgaga aaagcagaag tgagagcttc tcgccttgtg acattaagtt
    65101 gcctggccct acggatgaaa agtttcgaag aaacgctatc ataacgtgcg ggcttgtata
    65161 tttacaagtc cgctattgtt tttctctaat aaaacaaaag aggtgaaaac catagcaaag
    65221 caagacttat tcatcaatga tgagattcgt gtacgtgaag ttcgcttgat tggtcttgaa
    65281 ggagaacagc taggtatcaa gccactcagt gaagcgcaag ctttggctga taacgctaat
    65341 gttgacctag tattgattca accccaagcc aaaccgcctg ttgcaaaaat tatggactac
    65401 ggtaagttca aatttgagta ccagaagaag caaaaagaac aacgtaaaaa acaaagcgtt
    65461 gttactgtga aagaagttcg tctaagtcca acaattgaca agggtgactt tgatacaaaa
    65521 cttcgtaatg cacgtaagtt ccttgaaaaa ggaaataaag ttaaggtatc tattcgcttt
    65581 aagggtcgta tgattaccca taaagagatt ggtgcaaaag ttttagccga gtttgctgaa
    65641 gcaactcaag atattgccat catcgaacaa cgtgctaaaa tggatggacg tcaaatgttc
    65701 atgcaattgg cgccagcgac tgacaaaaaa taattgtcag aaagttaaat aaaggagaaa
    65761 aaatcatgcc aaaacaaaaa acacaccgcg catcagctaa acgtttcaaa cgtacaggtt
    65821 ctggtggact taaacgtttc cgtgcttaca cttctcaccg tttccacgga aaaactaaga
    65881 aacaacgtcg tcatcttcgt aaagcatcta tggtgcattc aggagattac aaacgtatca
    65941 aagcaatgct tactcgcttg aaataatagc ttgactgtaa gtaaacaatt ctaggaaata
    66001 tttggaggaa ataaaacatg gcacgtgtta aaggtggcgt tgtatcacgc aaacgtcgta
    66061 aacgtattct taaattagca aaaggttact atggagctaa acacatcttg ttccgtactg
    66121 caaaagaaca agtaatgaac tcttactact atgcataccg tgaccgtcgt cagaaaaaac
    66181 gtgacttccg caaattgtgg attactcgta tcaatgcggc agctcgtatg aacggacttt
    66241 catactcaca attgatgcat ggtttgaaat tggctgagat tgaagttaac cgtaaaatgc
    66301 ttgctgactt ggctgttaac gatgcagtag ctttcacagc tcttgcagat gcagctaaag
    66361 caaaacttgg taaataataa ctgatgagac tggaacagga ttgtccagtc tttttaaaaa
    66421 taaaggagaa agatatggct tcaaaaatgc tacacacttg cttacgagta gaaaatcttg
    66481 aaaaatcaat cgcattttat caagatgctt ttggttttaa agaattgcgt cgcagagatt
    66541 ttccagacca tgccttcacg attgtctatc taggtcttga gggtgatgat tatgagttgg
    66601 agttgactta taactacgat cacggtccgt atgtggttgg tgatgggttt gcccatatcg
    66661 ccctcagtac acctgatctt gaggcacttc atcaagaaca cagtgcaaaa ggctatgaag
    66721 tgactgagcc aaatggtcta ccaggaacta caccaaacta ttactttgtt aaagaccctg
    66781 atggatataa ggtcgaagtc attcgtgaaa aataatttcg tgcaagttaa gtagaatatt
    66841 cgttttctac ttgacttttt ttagctgaaa gagtatacta ataaaaattc aacctttaag
    66901 gggagtccag agagactcac aaggtgtcag ataaaagaat agtgcaattt tctagaggag
    66961 accttttgag tgtgctctct tgtgttgtac gattttaact gaggccttgc actagcaagg
    67021 tcttttcttt atctggtccc cttaaaattt aaggaggaaa agttatgaat ctcacatgta
    67081 agaagcgttt gggtgtcatt cggttggaaa ccatgaaggt ggttgcacaa gaggaaatcg
    67141 cgccagcaat ctttgaatta gtcctagaag gagaaatggt tgaagccatg cgagcaggcc
    67201 aatttcttca tctgcgtgta ccagacgatg cccatctctt acgtcgtcct atttcaattt
    67261 cgtctattga caaggcaaac aagcagtgtc acctcattta tcggattgag ggagctggga
    67321 ctgcaatttt ttcaacctta agtcagggag acactcttga tgtgatgggg cctcagggaa
    67381 atggttttga cttgtctgac cttgatgagc agaatcaggt tctccttgtt ggtggtggga
    67441 ttggtgttcc acccttgctt gaggtggcca aggaattgca tgaacgtgga gtgaaagtag
    67501 tgacagtcct cggttttgct aataaggatg ctgttatttt gaaaacggaa ttggctcagt
    67561 atggtcaggt ctttgtaacg acagatgatg gttcttatgg catcaaggga aatgtttccg
    67621 ttgttatcaa tgatttagat agtcagtttg atgctgttta ctcgtgtggg gctccaggaa
    67681 tgatgaagta tatcaatcaa acctttgatg atcacccaag agcctattta tctctggaat
    67741 ctcgtatggc ttgtgggatg ggagcttgct atgcctgtgt tctaaaagta ccagaaagcg
    67801 agacggtcag ccaacgcgtc tgtgaagatg gtcctgtttt ccgcacagga acagttgtat
    67861 tataaggaga aaattatgac tacaaatcga ttacaagtgt ctctacctgg tttggatttg
    67921 aaaaatccga ttattccagc atcaggctgt tttggctttg gacaagagta tgccaagtac
    67981 tatgatttaa accttttagg ttctattatg atcaaggcga caacccttga accacgtttt
    68041 gggaacccaa ctccaagagt ggcagagacg cctgctggta tgctcaatgc aattggcttg
    68101 caaaatcctg gtttagaggt tgttttggct gaaaagctac cttggctgga aagagaatat
    68161 ccaaatcttc ctattattgc caatgtagct ggtttttcaa aacaagagta tgcagctgtt
    68221 tctcatggga tttccaaggc aactaatgta aaagctatcg agctcaatat ttcttgtccc
    68281 aatgttgacc actgtaatca tggacttttg attggtcaag atccagattt ggcttatgat
    68341 gtggtgaaag cagctgtgga agcctcagaa gtgccagttt atgtcaaatt aaccccgagt
    68401 gtgaccgata tcgttactgt cgcaaaagct gcagaagatg cgggagcaag tggcttgacc
    68461 atgatcaata ctctggttgg aatgcgcttt gacctcaaaa ccagaaaacc aatcttggcc
    68521 aatggaacag gtggaatgtc aggtccagca gtctttccag tagccctcaa actcatccgc
    68581 caagtagccc aaacaacaga cctgcctatc attggaatgg ggggagtgga ttcggctgaa
    68641 gctgccctag aaatgtatct ggctggggca tctgctatcg gagttggaac agctaacttt
    68701 accaatcctt atgcctgccc tgacatcatc gaaaatttac caaaagtcat ggataaatac
    68761 ggtattagca gtctggaaga actccgtcag gaagtaaaag agtctctgag gtaaactgca
    68821 atcaatctgt tcttgatttt ttattagttt gtaatatgaa tttaggagaa ttttggtaca
    68881 ataaaataaa taagaacaga ggaagaaggt taatgaagaa agtaagattt atttttttag
    68941 ctctgctatt tttcttagct agtccagagg gtgcaatggc tagtgatggt acttggcaag
    69001 gaaaacagta tctgaaagaa gatggcagtc aagcagcgaa tgagtggatt tttgatactc
    69061 attatcaatc ttggttctat ataaaagcag atgctaacta tgctgaaaat gaatggctaa
    69121 agcaaggtga cgactatttt tacctcaaat ctggtggcta tatggccaaa tcagaatggg
    69181 tagaagacaa gggagccttt tattatcttg accaagatgg aaagatgaaa agaaatgctt
    69241 gggtaggaac ttcctatgtt ggtgcaacag gtgccaaagt aatagaagac tggatctatg
    69301 attctcaata cgatgcttgg ttttatatca aagcagatgg acagcacgca gagaaagaat
    69361 ggctccaaat taaagggaag gactattatt tcaaatccgg tggttatcta ctgacaagtc
    69421 agtggattaa tcaagcttat gtgaatgcta gtggtgccaa agtacagcaa ggttggcttt
    69481 ttgacaaaca ataccaatct tggttttaca tcaaagaaaa tggaaactat gctgataaag
    69541 aatggatttt cgagaatggt cactattatt atctaaaatc cggtggctac atggcagcca
    69601 atgaatggat ttgggataag gaatcttggt tttatctcaa atttgatggg aaaatagctg
    69661 aaaaagaatg ggtctacgat tctcatagtc aagcttggta ctacttcaaa tccggtggct
    69721 acatggcagc caatgaatgg atttgggata aggaatcttg gttttacctc aagtttgatg
    69781 gcaaaatggc tgaaaaagaa tgggtctacg attctcatag tcaagcctgg tactacttca
    69841 aatccggtgg ttacatgaca gccaatgaat ggatttggga taaggaatct tggttttatc
    69901 tcaaatctga tgggaaaata gctgaaaaag aatgggtcta cgattctcat agtcaagctt
    69961 ggtactactt caaatccggt ggttacatga cagccaatga atggatttgg gataaggaat
    70021 cttggtttta cctcaagtct gatggcaaaa tggctgaaaa agaatgggtc tacgattctc
    70081 atagtcaagc ctggtactac ttcaaatctg gtggctacat ggcgaaaaat gagacagtag
    70141 atggttatca gcttggaagc gatggtaaat ggcttggagg aaaagctaca aataaaaatg
    70201 ctgcttacta tcaagtagtg cctgtcacag ccaatgttta tgattcagat ggtgaaaagc
    70261 tttcctatat atcgcaaggt agtgtcgtat ggctagataa ggatagaaaa agtgatgaca
    70321 agcgcttggc tattactatt tctggtttgt caggctatat gaaaacagaa gatttacaag
    70381 cgctagatgc tagtaaggac tttatccctt attatgagag tgatggccac cgtttttatc
    70441 actatgtggc tcagaatgct agtatcccag tagcttctca tctttctgat atggaagtag
    70501 gcaagaaata ttattcggca gatggcctgt attttgatgg ttttaagctt gagaatccct
    70561 tccttttcaa agatttaaca gaggctacaa actacagtgc tgaagaattg gataaggtat
    70621 ttagtttgct aaacattaat aatagccttt tggagaacaa gggcgctact tttaaggaag
    70681 ccgaagaaca ttaccatatc aatgcccttt atctccttgc ccatagtgcc ctagaaagta
    70741 actggggaag aagtaaaatt gccaaagata agaataattt ctttggcatt acagcctatg
    70801 atacgacccc ttacctttct gccaagacat ttgatgatgt ggataaggga attttaggtg
    70861 caaccaagtg gattaaggaa aattatatcg ataggggaag aactttcctt ggaaacaagg
    70921 cttctggtat gaatgtggaa tatgcttcag acccttattg gggcgaaaaa attgctagtg
    70981 tgatgatgaa aatcaatgag aagctaggtg gcaaagatta gtactataag tgaatatgat
    71041 ttgagtgaat agtaagttaa aaatcctgat ttcaagtaaa atcaggattt tttcatggat
    71101 gcaatttttt tggagtctgg tgtgacgcgg agggtctttt gtcctgtgta agtgacaaag
    71161 ccgggttttc caccagttgg tttattgagt tttttgactt caatcatatc tacctgcacc
    71221 agattcgaca ggcgcccttg agagaagtag gcagctaact ctgctgcgtc tgtcttgact
    71281 gcatcagatg ggtcaagatt tcctgagatg acaacatggc ttccaggaat gtccttagca
    71341 tggaaccaaa gttcctcctt gcgggccatt ttaaaggtca attcctcatt ttgaagattg
    71401 tttcgtccga catagatgat ggttttgcca tcgcttgcta gatattgttc tagttttttg
    71461 cgtttctgga ttttctcccg ttgtcttctg cggataaaac ctgtttgaat caattcttcg
    71521 cggatttcag cgatttcttc cagtccagct tggttgagga cggtttctac actttccaga
    71581 tagagaatag tggctttggt ttcttcaatc aaatcagtca agtatttgac agcttctttg
    71641 agtttctgat accgtttaaa atagcgttgg gcattctggt tgggagtcag agccttatca
    71701 agcgcaatca tgataggttg gttggtatag tagttgtcta ggataacctg gtcttggtcg
    71761 ttaggcactt ggtgtaggaa ggttgtcagc aattctcctt tttgacgaaa ttcttcagcg
    71821 ttgtctgtcg ccagtaactc tttttcctgt tttttgagtt tgtgtcggtt tttctgaagt
    71881 tcattttcaa cacgacgaat cagttcactg gcctgctgtt tgacgcggtc gcgctcagcc
    71941 ttatccttat agtaggtgtc caacaaatca gaaagatttg caaaaggctc tcccacctga
    72001 tttgcaaaag gaactggact gaaggaagtc tcagtcaagc atggcttggt ttcctgattg
    72061 aaaaaatttc ggaaagcgga aagtttttca ctaaccagta tcctttccaa ttcatttgcc
    72121 gtatcgcgtc ccagaccttg aaagaggctt tgaagatttt ttgctgttag ttcttgggtt
    72181 tgcaggattt caaagagctt ttcatccttg atagtaaaag gattgagaga ttctgtactt
    72241 ggcggagcga tataggtcga tcctggaagt aaggtgcggt agctattttg tgaaaagccg
    72301 acgtgtttga taacttcgag gattttatga ctgcttttat cgaccagtag aatattactg
    72361 tgtttcccca taatttcgat aatcaaggta gcctggatat ggtctccaat ctcgttttta
    72421 ttggaaactg taatttccac aatacggtca ttttccactt gctcaatcga ctcaatcagg
    72481 gccccctgca aatactttct caaaaccatg ataaaggtag aaggttgggc tggattttca
    72541 aaagtcgttt gggtcagctg aatgcgtcca aaaactggat gggcagaaag gagcaggcga
    72601 tggctttggc gattgctgcg gatttgcaag accaactctt gttcaaaagg ctgattgatt
    72661 ttctggatgc gaccattcac taattcgctt cgcaattcct caactatgtg gtgtaaaaaa
    72721 aatccgtcaa atgacatcgt tctctccttg tgattgtatt ccatagtatt atatcaaaaa
    72781 ggtagaataa aatcatggaa atgtggtata ataaagccaa gtaaagagaa acgagaagca
    72841 catgtatatt gaaatggtag atgaaactgg tcaagtttca aaagaaatgt tgcaacaaac
    72901 ccaagaaatt ttggaatttg cagcccaaaa attaggaaaa gaagacaagg agatggcagt
    72961 cacttttgtg accaatgagc gtagtcatga acttaatctg gagtaccgtg acaccgaccg
    73021 tccgacagat gtcatcagcc ttgagtataa accagaattg gaaattgcct ttgacgaaga
    73081 ggatttgctt gaaaatccag aattggcaga gatgatgtct gagtttgatg cctatattgg
    73141 ggaattgttc atctctatcg ataaggctca tgagcaggcc gaagaatatg gtcacagctt
    73201 tgagcgtgag atgggcttct tggcagtaca cggcttttta catattaacg gctatgatca
    73261 ctacactccg gaagaagaag cggagatgtt cggtttacaa gaagaaattt tgacagccta
    73321 tggactcaca agacaataaa cgaaaatgga aaaatcgtga cttgatatcc agtttagaat
    73381 ttgccatcac agggattttt actgctatca aggaagaacg aaatatgcga aaacatgcag
    73441 tgacggctct agtggtcatc cttgcaggtt ttgtttttca ggtgtcacga atcgaatggc
    73501 tctttcttct attgagtatt ttcttggtag tagcctttga gattatcaac tctgctattg
    73561 aaaatgtggt ggatttggcc agtcactatc acttttccat gctggctaaa aatgccaagg
    73621 atatggcggc cggcgcggta ttagtggttt ctcttttcgc agccttaaca ggcgcattga
    73681 tttttctccc acgaatctgg gatttattat tttaaacagt aagaggaaat tatgactttt
    73741 aaatcaggct ttgtagccat tttaggacgt cccaatgttg ggaagtcaac ctttttaaat
    73801 cacgttatgg ggcaaaagat tgccatcatg agtgacaagg cgcagacaac gcgcaataaa
    73861 atcatgggaa tttacacgac tgataaggag caaattgtct ttatcgacac accagggatt
    73921 cacaaaccta aaacagctct cggagatttc atggttgagt ctgcctatag tacccttcgc
    73981 gaagtggaca ccgttctttt catggtgcct gctgatgaag cgcgtggtaa gggggacgat
    74041 atgattatcg agcgtctcaa ggctgccaag gttcctgtga ttttggtggt gaataaaatc
    74101 gataaggtcc atccagacca gctcttgtct cagattgatg acttccgtaa tcaaatggac
    74161 tttaaggaaa ttgttccaat ctcagccctt cagggaaata acgtgtctcg tctagtggat
    74221 attttgagtg aaaatctgga tgaaggtttc caatatttcc cgtctgatca aatcacagac
    74281 catccagaac gtttcttagt ttcagaaatg gttcgcgaga aagtcttgca cctaactcgt
    74341 gaagagattc cgcattctgt agcagtagtt gttgactcta tgaaacgaga cgaagagaca
    74401 gacaaggttc acatccgtgc aaccatcatg gtcgagcgcg atagccaaaa agggattatc
    74461 atcggtaaag gtggcgctat gcttaagaaa atcggtagca tggcccgtcg tgatatcgaa
    74521 ctcatgctag gagacaaggt cttcctagaa acctgggtca aggtcaagaa aaactggcgc
    74581 gataaaaagc tagatttggc tgactttggc tataatgaaa aagaatacta agtagaggtg
    74641 ggctcatgcc tgcttcttgt tttacagaag gaggacttat gcctgaatta cctgaggttg
    74701 aaaccgtttg tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa
    74761 ttcgctaccc caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc
    74821 agattatcga gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg
    74881 tcttgatttc ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg
    74941 aacgcaagca tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg
    75001 atgttcgcaa gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta
    75061 tttctaaaaa attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat
    75121 ctgcccttgc caagtccaaa aagcctatca aatcccatct cctagaccag accttggtaa
    75181 ctggacttgg caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta
    75241 gatcttccca gactttgaca gcagaagaag cgacagctat tcatgaccaa accattgctg
    75301 ttttgaacca ggctgttgaa aaaggcggtt ccaccattcg gacctatacc aatgcctttg
    75361 gggaagatgg aagcatgcag gattttcatc aggtctatga taagactggt caagaatgtg
    75421 tacgctgtgg taccatcatt gagaaaattc aactaggcgg acgaggcacc cacttttgtc
    75481 caaactgtca aaggagggac tgatgagaaa aatcatcgga atcactgggg gaattgcctc
    75541 tggtaagtca actgtgacaa attttctaag acagcaaggc tttcaagcag tggatgccga
    75601 cgcagtcgtc caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca
    75661 ctttgggcaa gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct
    75721 catcttttca aatcctgaag agcaaaaatg gtctaagcaa attcaagggg agattatccg
    75781 tgaggaactg gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga
    75841 tattccccta ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta
    75901 tgtggaccga gatacccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga
    75961 agctgagtct cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca
    76021 ggttcttgat aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga
    76081 gggaggtagg caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg
    76141 gtaattttct gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg
    76201 aaaatctagg tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct
    76261 ctgctatttc cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc
    76321 gaaaacccat gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct
    76381 ttgtcccaaa tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt
    76441 ttgttcctaa tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg
    76501 ccttaggtac tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg
    76561 gctttatcgc agaattattt ggcattcgta cagttttctt actggttggt agttttctat
    76621 ttttagctgc tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg
    76681 aaaaggctat tccaacaaag gaattgttta cttcagttaa atatccctat cttttgctca
    76741 atctcttttt aaccagtttt gtcatccaat tttcagctca atcgattggc cctattttgg
    76801 ctctttatgt acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg
    76861 tgtccagtat gggcttttcc agcatgatga gtgcaggagt catgggcaag ctaggtgaca
    76921 aggtgggcaa tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc
    76981 tctgtgccaa tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggcttgg
    77041 gaaccggtgc gctgatacct ggggtcaatg ccattctcag caaaatgact cccaaagccg
    77101 gcatttcgag ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc
    77161 ccatggcagg ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacaa
    77221 gcctttgtgt tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag
    77281 taaaggaaat ctagtgcgag taaaaattaa tctcaaatgc tcctcttgtg gcagtatcaa
    77341 ttacctaacc agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg
    77401 tcccaaggaa agaaaagtaa ccctacatct tgaatttaag tagattttat ggtaaaataa
    77461 tagggatttt aaggagtttg atatgtataa cctattatta accattttat tagtattatc
    77521 tgttgtgatt gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt
    77581 tgatgccagt tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat
    77641 gcagcgtttg acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt
    77701 attatcaagt agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta
    77761 aaggatgttt gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg
    77821 aaagatagaa taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct
    77881 caggctttgg gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta
    77941 atggaaagaa agcaccaaat tcgttttgaa gaagatggta gtctgacatt agaaattaag
    78001 aaaaaacatg agattaccct caaggggatt tttcatgccc ataaaaacgg ctttggcttt
    78061 gttagtctgg aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct
    78121 attgatggtg ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca
    78181 gcagcagaag ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa
    78241 atcgttctgg atcaggaaaa gcctaagtat gctggctata ttcgttcaaa aaatcagaaa
    78301 atcagtcaac cgatttatgt taagaaacca gccctaaagt tagaaggaac agaagttctc
    78361 aaggtcttta tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc
    78421 gatgtggtgg gacactcaac ggatgtcgga attgatgttc ttgaggtctt ggaatcaatg
    78481 gacattgtat ccgagtttcc agaaactgtt gtcaaggaag cagaaagtgt gcctgatgct
    78541 ccgtctcaaa aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt
    78601 gacggtgcgg atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc
    78661 aatctggagc ttggggttca catcgcagat gtttcctatt atgtgaccga gggttctgcc
    78721 cttgacaagg aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca
    78781 atgcttccag aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg
    78841 acccagtctg ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca
    78901 caaacagtta tcaagaccag ttttcgtatg acctatagcg atgtcaatga tatcctagct
    78961 ggcgatgaag aaaagagaaa agaataccat aaaattgtac caagtatcga actcatggcc
    79021 aagcttcatg aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc
    79081 aatgaagcga agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag
    79141 cgtggcattg ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc
    79201 gaacatttca gcaagttgga tttgcctttt atctaccgaa ttcacgagga gcctaaggct
    79261 gaaaaggttc agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatgggact
    79321 gccagtgaga ttagccagga ggcacttcaa gacatcatgc gtgctgttga gggagaacct
    79381 tatgcagatg tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag
    79441 cacaatcacg gccactatgg actagctgct gactattata ctcactttac cagtccaatt
    79501 cgtcgttatc cagaccttct tgttcaccgt atgattcggg attacggccg ttctaaggaa
    79561 atagcagagc attttgaaca agtgattcca gagattgcga cccagtcttc caaccgtgaa
    79621 cgtcgtgcca tagaagctga gcgtgaagtc gaagccatga aaaaggctga gtatatggaa
    79681 gaatacgtgg gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt
    79741 gtcgaattgc caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat
    79801 catttcaatg agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg
    79861 ggtcagcaga tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt
    79921 tcattcgtac ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcgtagt
    79981 ggcagagggc gtggttcaaa tcgtcgttcg gataagaagg aagacaagag aaaatcagga
    80041 cgctcaaatg ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct
    80101 ttttacaagg aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt
    80161 cgcacaaaat aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat
    80221 ggtcctgact ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg
    80281 ctttgctcaa gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga
    80341 agagggcaat atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa
    80401 gcaaattcaa aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa
    80461 ggtctatata aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga
    80521 ctatgacaaa cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat
    80581 gaaagctgtt aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa
    80641 acgcatgcct ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac
    80701 aaaagttggg acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt
    80761 gacagaagaa ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat
    80821 ggcccaacct caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt
    80881 ggaattttat tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca
    80941 ttcagaggtc ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttaggttg
    81001 tggtcagggg cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga
    81061 tcaaaatgga ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat
    81121 gcctgttggc ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt
    81181 ttcaacagtt gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat
    81241 gcaggagaaa accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga
    81301 ttatccttgc tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta
    81361 caaggattgg gaattggtta agtacaatga aaatccaggc catttgcatc gtcgcgatga
    81421 gaatggcaat cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac
    81481 acacatgaag attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag
    81541 gagggaattc atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga
    81601 taaacttgag aagcaagcat acacctgccc agcttgtgga ggccagctcc atttgcgtca
    81661 aggaccaagt gtacggacgc attttgccca taaatcctta aaagactgtg attttttctt
    81721 tgaaaatgaa agtccagaac acctggccaa taaggaatcc ctctatcact ggttaaaaaa
    81781 agagacaaag gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt
    81841 tgtaaatggc aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa
    81901 agagcgaagt gagggctatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa
    81961 actgtggctc aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa
    82021 catgggcttt tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct
    82081 gatttaccag gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca
    82141 aggtagttta ttggaaatat tgcgtcttcc ctataagaga caaaaaatat ctcattttac
    82201 agtttctgag gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct
    82261 cttttggatg aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg
    82321 actgaaagaa tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca
    82381 agacttgact agctattatc agtactttta tacctattac caaaaaaatc ctcaaaatga
    82441 ttggcaaaag ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga
    82501 ataaaaagga tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac
    82561 atgggatcta tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt
    82621 aacagaacaa ttggagacag tagcccagta tgaaggccat ctcttggata gtgcggataa
    82681 cctactagaa atcactgaat tttctcttga aatggaacgc cagatggaga agctttacgt
    82741 ttatgctcat atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc
    82801 caaggccatg acactctaca gccagttaga ccaagccttt tcattctatg atcctgaatt
    82861 tatggagatt agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt
    82921 ttatcaacac tattttgaca agctcttgaa aggcaaggat cacgttcttt cacaacgtga
    82981 agaagaatta ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat
    83041 cttggacaat gcggatattg tgttccctta tgtcctagac gatgatggta aagaagttca
    83101 gctatctcat gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg
    83161 tgcctatcaa gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacctt
    83221 gcaaaccaat gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg
    83281 tcatgcagcc ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc
    83341 agttcgcaag catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg
    83401 gatttcagat ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacagttt
    83461 tacctaccaa gaagccttga aaaaagcaga agatgctttg gcagtcttgg gtgaggatta
    83521 cttgagccgt gttaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg
    83581 caagcgttca ggtgcctact ctggtggttc ttacgatacc aatgccttta tgcttctcaa
    83641 ctggcaggac aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca
    83701 ttcaagctat actcgtgaaa ctcagcctta tgtttacgga gattactcta tctttttggc
    83761 tgagattgcc tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga
    83821 agacgacgca acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt
    83881 tttccgccaa actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg
    83941 ggaggtcttg acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta
    84001 tggtttgagt aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt
    84061 ctactataac tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc
    84121 tgaaaaaatt gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc
    84181 aggtaagtcg gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga
    84241 agactacctc aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct
    84301 tgttgaaaaa ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata
    84361 acatgcgtcg tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc
    84421 aggtcacagg tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta
    84481 ttccccatga aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata
    84541 ttctggaaat tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa
    84601 atgctaagat tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt
    84661 ttgcccagtt tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gtggatgtct
    84721 tatctacact gacagagtct tatgatttcg tatttatgga ttctgccaag tctaaataca
    84781 tcgtctttct gccagaaatc ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg
    84841 atatttttca aggtggtgat gttgccaagg atattatgga agtccgtcgt ggtcagcgaa
    84901 ccatttatcg aggccttcaa aaattatttg atgcaacctt agacaatcca gaactcaccg
    84961 caacattagt gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc
    85021 aactgtctga aagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga
    85081 gtaacactta tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac
    85141 tattatcagt agcaacttta gcagcttgtt cgaaagggtc agaaggagca gaccttatca
    85201 gcatgaaagg ggatgtcatc acagaacatc aattttatga gcaagtgaaa aacaaccctt
    85261 cagcccaaca agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct
    85321 cagagcttga tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg
    85381 aaaactacca acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa
    85441 ttcgtacaag taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag
    85501 atgaagccta taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc
    85561 gtcttaataa tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg
    85621 attttgctca attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag
    85681 aaattacctt tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg
    85741 ctttagatgt ggatggtgtt tctgatgtga ttacagcaac tggcacacaa gcctacagta
    85801 gccaatatta cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact
    85861 acaaagaaaa attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc
    85921 aaagcattat cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc
    85981 aaaatatctt tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa
    86041 acgaatagtc caaatcaatg agtcagggaa aaaactcgac ttcaggaaaa aatgaagcaa
    86101 acattcccac aataaaacgc atagtacaag gtttgtactg ccccccaaaa aagttagaca
    86161 attaatttat ccgaaggatt t
//
LOCUS       DAVLHB010000003        82364 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLHB010000003 DAVLHB010000000
VERSION     DAVLHB010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.003"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..860
                     /locus_tag="VXE36_000183"
     CDS             <1..860
                     /locus_tag="VXE36_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0778560.1"
                     /translation="QPKPAPAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQP
                     PKAEKPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSN
                     GAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGDMATGWLQYNGSWYYLN
                     ANGDMATGWFQNNGSWYYLNANGDMATGWLQYNGSWYYLNSNGAMVTGWLQNNGSWYY
                     LNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDSYR
                     VNANGEWVN"
     gene            complement(1090..2070)
                     /gene="dusB"
                     /locus_tag="VXE36_000184"
     CDS             complement(1090..2070)
                     /gene="dusB"
                     /locus_tag="VXE36_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0778561.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWAGPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(2057..2929)
                     /gene="hslO"
                     /locus_tag="VXE36_000185"
     CDS             complement(2057..2929)
                     /gene="hslO"
                     /locus_tag="VXE36_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0778562.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            3094..4521
                     /locus_tag="VXE36_000186"
     CDS             3094..4521
                     /locus_tag="VXE36_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0778563.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKVELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4679..6187
                     /gene="glpK"
                     /locus_tag="VXE36_000187"
     CDS             4679..6187
                     /gene="glpK"
                     /locus_tag="VXE36_000187"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0778564.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            6229..8055
                     /gene="glpO"
                     /locus_tag="VXE36_000188"
     CDS             6229..8055
                     /gene="glpO"
                     /locus_tag="VXE36_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0778565.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEVFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            8125..8829
                     /locus_tag="VXE36_000189"
     CDS             8125..8829
                     /locus_tag="VXE36_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0778566.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            9183..9329
                     /locus_tag="VXE36_000190"
     CDS             9183..9329
                     /locus_tag="VXE36_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004247184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778567.1"
                     /translation="MLVEFHKSQGTLETPEAQAEIAQKREEIEQRRAELEGKKQELLN
                     RLNK"
     gene            complement(9416..10023)
                     /locus_tag="VXE36_000191"
                     /pseudo
     CDS             complement(9416..10023)
                     /locus_tag="VXE36_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11101..12378
                     /gene="ltrA"
                     /locus_tag="VXE36_000192"
     CDS             11101..12378
                     /gene="ltrA"
                     /locus_tag="VXE36_000192"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV0778568.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMIKTKITRPRELKYLGFGFW
                     KSSDGWKIRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            12830..14008
                     /locus_tag="VXE36_000193"
     CDS             12830..14008
                     /locus_tag="VXE36_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0778569.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            14322..14453
                     /locus_tag="VXE36_000194"
     CDS             14322..14453
                     /locus_tag="VXE36_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0778570.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            14474..16024
                     /gene="dltA"
                     /locus_tag="VXE36_000195"
     CDS             14474..16024
                     /gene="dltA"
                     /locus_tag="VXE36_000195"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0778571.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            16021..17265
                     /gene="dltB"
                     /locus_tag="VXE36_000196"
     CDS             16021..17265
                     /gene="dltB"
                     /locus_tag="VXE36_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0778572.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            17279..17518
                     /gene="dltC"
                     /locus_tag="VXE36_000197"
     CDS             17279..17518
                     /gene="dltC"
                     /locus_tag="VXE36_000197"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0778573.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            17511..18779
                     /gene="dltD"
                     /locus_tag="VXE36_000198"
     CDS             17511..18779
                     /gene="dltD"
                     /locus_tag="VXE36_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0778574.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18934..19374
                     /gene="adcR"
                     /locus_tag="VXE36_000199"
     CDS             18934..19374
                     /gene="adcR"
                     /locus_tag="VXE36_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0778575.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            19374..20078
                     /locus_tag="VXE36_000200"
     CDS             19374..20078
                     /locus_tag="VXE36_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0778576.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            20071..20877
                     /locus_tag="VXE36_000201"
     CDS             20071..20877
                     /locus_tag="VXE36_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0778577.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20887..22392
                     /gene="adcA"
                     /locus_tag="VXE36_000202"
     CDS             20887..22392
                     /gene="adcA"
                     /locus_tag="VXE36_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0778578.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(23554..24327)
                     /locus_tag="VXE36_000203"
     CDS             complement(23554..24327)
                     /locus_tag="VXE36_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0778579.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            24503..25906
                     /locus_tag="VXE36_000204"
     CDS             24503..25906
                     /locus_tag="VXE36_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0778580.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSTLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEDSLFISSGTWSLVGVELSSPILSTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMYKTLTEYLAYHHETGEWTDGQLFKIVYESLAETYKETIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEATAVGNICIQLLSQGKINEDTGLK
                     DIMTNIADTQYYYPQLS"
     gene            25935..27227
                     /locus_tag="VXE36_000205"
     CDS             25935..27227
                     /locus_tag="VXE36_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0778581.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLAAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPDQWNTWEDFTQAMAAVRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVHTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            27314..28243
                     /locus_tag="VXE36_000206"
     CDS             27314..28243
                     /locus_tag="VXE36_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0778582.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            28246..29085
                     /locus_tag="VXE36_000207"
     CDS             28246..29085
                     /locus_tag="VXE36_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0778583.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            29082..30401
                     /locus_tag="VXE36_000208"
     CDS             29082..30401
                     /locus_tag="VXE36_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0778584.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            30407..32278
                     /locus_tag="VXE36_000209"
     CDS             30407..32278
                     /locus_tag="VXE36_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEV0778585.1"
                     /translation="MKIENKNVRRNFFWGDGRFYTTDIVNKRAGVMIENVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDTRIQVSFVCPSLRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYLGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKHLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDSQYQEFLEKREIQLPMWSLYNHEPIYAVSANTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            32300..34516
                     /locus_tag="VXE36_000210"
     CDS             32300..34516
                     /locus_tag="VXE36_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0778586.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLLQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            34527..37544
                     /locus_tag="VXE36_000211"
     CDS             34527..37544
                     /locus_tag="VXE36_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEV0778587.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETV
                     RVTGNNLEKLITKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLPKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            37559..38287
                     /locus_tag="VXE36_000212"
     CDS             37559..38287
                     /locus_tag="VXE36_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEV0778588.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            38300..40066
                     /locus_tag="VXE36_000213"
     CDS             38300..40066
                     /locus_tag="VXE36_000213"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0778589.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            40212..41363
                     /locus_tag="VXE36_000214"
     CDS             40212..41363
                     /locus_tag="VXE36_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0778590.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            41508..42392
                     /locus_tag="VXE36_000215"
     CDS             41508..42392
                     /locus_tag="VXE36_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0778591.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(42510..42587)
                     /locus_tag="VXE36_000216"
                     /pseudo
     CDS             complement(42510..42587)
                     /locus_tag="VXE36_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            42791..43042
                     /locus_tag="VXE36_000217"
     CDS             42791..43042
                     /locus_tag="VXE36_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0778592.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            43030..43320
                     /locus_tag="VXE36_000218"
     CDS             43030..43320
                     /locus_tag="VXE36_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778593.1"
                     /translation="MGALGYYEGFVPYVSNQYQNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(43725..45056)
                     /locus_tag="VXE36_000219"
     CDS             complement(43725..45056)
                     /locus_tag="VXE36_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0778594.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(45078..46589)
                     /locus_tag="VXE36_000220"
     CDS             complement(45078..46589)
                     /locus_tag="VXE36_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0778595.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGSFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(46800..47747)
                     /gene="arcC"
                     /locus_tag="VXE36_000221"
     CDS             complement(46800..47747)
                     /gene="arcC"
                     /locus_tag="VXE36_000221"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0778596.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(47912..48928)
                     /gene="argF"
                     /locus_tag="VXE36_000222"
     CDS             complement(47912..48928)
                     /gene="argF"
                     /locus_tag="VXE36_000222"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0778597.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPDKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(48986..50215)
                     /gene="arcA"
                     /locus_tag="VXE36_000223"
     CDS             complement(48986..50215)
                     /gene="arcA"
                     /locus_tag="VXE36_000223"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0778598.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            50970..52649
                     /locus_tag="VXE36_000224"
     CDS             50970..52649
                     /locus_tag="VXE36_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0778599.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTLLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLDLDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(52689..54773)
                     /locus_tag="VXE36_000225"
     CDS             complement(52689..54773)
                     /locus_tag="VXE36_000225"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0778600.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDMATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            54944..56224
                     /locus_tag="VXE36_000226"
     CDS             54944..56224
                     /locus_tag="VXE36_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0778601.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLSYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     SYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            56315..58960
                     /locus_tag="VXE36_000227"
     CDS             56315..58960
                     /locus_tag="VXE36_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0778602.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVRADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            59044..59913
                     /locus_tag="VXE36_000228"
     CDS             59044..59913
                     /locus_tag="VXE36_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0778603.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            59907..61787
                     /locus_tag="VXE36_000229"
     CDS             59907..61787
                     /locus_tag="VXE36_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0778604.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            62113..62328
                     /locus_tag="VXE36_000230"
     CDS             62113..62328
                     /locus_tag="VXE36_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778605.1"
                     /translation="MILWSFDFANDHAHAFFMDNVEWSHADSYFLSFVSDDVEERYIE
                     NVYLDSLSVKQKFKFIFDFGDEWCFEC"
     gene            complement(62491..62727)
                     /locus_tag="VXE36_000231"
     CDS             complement(62491..62727)
                     /locus_tag="VXE36_000231"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0778606.1"
                     /translation="MKIYPQAQTPRKSSKLKPLTVEDKACNHALSKERSKVENIFAKV
                     KTFKMISTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(63153..63329)
                     /locus_tag="VXE36_000232"
                     /pseudo
     CDS             complement(63153..63329)
                     /locus_tag="VXE36_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            63664..65349
                     /locus_tag="VXE36_000233"
     CDS             63664..65349
                     /locus_tag="VXE36_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEV0778607.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKD
                     KGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(65829..65978)
                     /gene="rpmG"
                     /locus_tag="VXE36_000234"
     CDS             complement(65829..65978)
                     /gene="rpmG"
                     /locus_tag="VXE36_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0778608.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(65994..66176)
                     /gene="rpmF"
                     /locus_tag="VXE36_000235"
     CDS             complement(65994..66176)
                     /gene="rpmF"
                     /locus_tag="VXE36_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0778609.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(66328..66528)
                     /locus_tag="VXE36_000236"
     CDS             complement(66328..66528)
                     /locus_tag="VXE36_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0778610.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(66531..67538)
                     /locus_tag="VXE36_000237"
     CDS             complement(66531..67538)
                     /locus_tag="VXE36_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0778611.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            67729..69759
                     /locus_tag="VXE36_000238"
     CDS             67729..69759
                     /locus_tag="VXE36_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0778612.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            69763..70047
                     /locus_tag="VXE36_000239"
     CDS             69763..70047
                     /locus_tag="VXE36_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0778613.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            70060..71406
                     /locus_tag="VXE36_000240"
     CDS             70060..71406
                     /locus_tag="VXE36_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0778614.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            71410..72267
                     /locus_tag="VXE36_000241"
     CDS             71410..72267
                     /locus_tag="VXE36_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0778615.1"
                     /translation="MILSKNREDELRKFAANIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPETFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            72264..73196
                     /locus_tag="VXE36_000242"
     CDS             72264..73196
                     /locus_tag="VXE36_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0778616.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            73429..75132
                     /gene="ilvD"
                     /locus_tag="VXE36_000243"
     CDS             73429..75132
                     /gene="ilvD"
                     /locus_tag="VXE36_000243"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0778617.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(75293..75373)
                     /locus_tag="VXE36_000244"
                     /pseudo
     CDS             complement(75293..75373)
                     /locus_tag="VXE36_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(75431..75772)
                     /locus_tag="VXE36_000245"
     CDS             complement(75431..75772)
                     /locus_tag="VXE36_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0778618.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            75896..76747
                     /gene="rgg"
                     /locus_tag="VXE36_000246"
                     /pseudo
     CDS             75896..76747
                     /gene="rgg"
                     /locus_tag="VXE36_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            76938..78185
                     /locus_tag="VXE36_000247"
     CDS             76938..78185
                     /locus_tag="VXE36_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0778619.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            78262..79551
                     /locus_tag="VXE36_000248"
     CDS             78262..79551
                     /locus_tag="VXE36_000248"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0778620.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            79548..79625
                     /locus_tag="VXE36_000249"
                     /pseudo
     CDS             79548..79625
                     /locus_tag="VXE36_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            79893..80207
                     /locus_tag="VXE36_000250"
     CDS             79893..80207
                     /locus_tag="VXE36_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778621.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            80217..80423
                     /locus_tag="VXE36_000251"
     CDS             80217..80423
                     /locus_tag="VXE36_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0778622.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            80423..80620
                     /locus_tag="VXE36_000252"
     CDS             80423..80620
                     /locus_tag="VXE36_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778623.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            80623..81357
                     /locus_tag="VXE36_000253"
     CDS             80623..81357
                     /locus_tag="VXE36_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0778624.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            81369..82010
                     /locus_tag="VXE36_000254"
     CDS             81369..82010
                     /locus_tag="VXE36_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0778625.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            82028..82258
                     /locus_tag="VXE36_000255"
     CDS             82028..82258
                     /locus_tag="VXE36_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778626.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT        25031 a        14732 c        17666 g        24935 t
ORIGIN      
        1 aacaaccaaa accagcgccg gctcctcaac cagctccagc accaaaacca gaaaaaacag
       61 atgatcaaca agctgaagaa gactatgctc gtagatcaga agaagaatat aaccgcttgc
      121 cccaacagca accgccaaaa gcagaaaaac cagctccagc tccagcacca aaaccagagc
      181 aaccagctcc cgcaccaaaa acgggctgga aacaagaaaa cggtatgtgg tacttctaca
      241 atactgatgg ttcaatggct acaggttggc tccaaaacaa cggttcatgg tactacctca
      301 acagcaatgg cgctatggct acaggttggc tccaatacaa cggttcatgg tattacctaa
      361 acgctaacgg cgctatggct acaggttggg ctaaagtcaa cggttcatgg tactacctca
      421 acgctaatgg tgatatggcg acaggatggc tccaatacaa tggttcatgg tactacctca
      481 acgctaatgg tgatatggcg acaggatggt tccaaaacaa tggttcatgg tactacctca
      541 acgctaatgg tgatatggcg acaggatggc tccaatacaa tggttcatgg tactacctaa
      601 acagcaatgg tgctatggta acaggatggc tccaaaacaa tggctcatgg tactacctca
      661 acgctaacgg ttcaatggca acagattggg tgaaagatgg agatacctgg tactatcttg
      721 aagcatcagg tgctatgaaa gcaagccaat ggttcaaagt atcagataaa tggtactatg
      781 tcaatggctc aggtgccctt gcagtcaaca caactgtaga tagctataga gtcaatgcca
      841 atggtgaatg ggtaaactaa acctaatata actagttaat actgacttcc tgtaagaact
      901 ctttaaagta ttccctacaa ataccatatc ctttcagtag ataatatacc cttgtaggaa
      961 gtttagatta aaaaataact ctgtaatctc tagccggatt tatagcgcta gagactacgg
     1021 agtttttttg atgaggaaag aatggcggca ttcaagaggc tctttaagag agttacgggt
     1081 tttaaactat taagccttct ccaattgcaa gagagcttca atctctgcta gggtgctagc
     1141 ttgcgaaatg gctccacgga gtttggcagc gccagatgtt ccccggagat agtgaggagc
     1201 gaggccgcgg aattcacgaa ctgcgacgtt ttctcctttg aggttaatca atcgtttcaa
     1261 gtgttcgtag gcgatcttca tcttgtcttc aaaggtcaaa tcaggtagga tttctcctgt
     1321 ttcaaagtaa tggttgattt ggttgaagag gtaaggattt cccatggcag ctcggccaat
     1381 catgactgcg tcagcaccaa cttcttcgat gcgttgcttg gcttcttgga cagtacggat
     1441 atcaccgttg gcgatgaatg gaatcttggt tagagcttgg gcaaccttgt aaagggtctc
     1501 aaggtctgcg tggccagtat acatttgttc acgggtacgg ccatgcatgg cgagggcaga
     1561 aacacctgca gcctcagcag cgagggcatt ttctactgca agagatgggc ccgcccagcc
     1621 ggtacgcatt ttgacagtaa gtgggatatc aaggacagac tggaccttgt tgatgataga
     1681 gtagatcttg tcaggatcct tgagccacat agcaccagct tcgttcttca cgattttgtt
     1741 gacagggcag cccatgttga tatcgacgat atcggtcttg gtattttctt ggatgaattc
     1801 tgctgcgcgt gctaggctgt cttcatcgct accaaaaagt tggatagaga cagggttttc
     1861 gccctcatcg atatgaagca tgtgcagggt tttttcgttg ttgtattgga ttcccttgtc
     1921 agagaccatt tccattacaa cgagtccagc tccgagctcc tttgcgatgg tacgaaaggc
     1981 tgagttggtc acgccagcca taggcgctaa aacggtacga ttgggaatct caacattgcc
     2041 aatcataaaa ggtgtattaa gatttgtcac gaatgagttc ctccaggtcc ttttcatcaa
     2101 agttgtaagt agtttggcag aattgacaag tgatttctgc cccgtggtct tcctctttca
     2161 tttcctgtaa gtctgagctt ggaaggctgg caagagcgtt cataaagcgt tcatggctac
     2221 agtcacattg gaaacggatt tcttcttcag aaagacgctt gtaggcttcg tccccgtaga
     2281 tagccttgag gagggcttcg atatggtcgt cgctttcgag aagagtagag atagctggca
     2341 tttcttggat gcgtttttca aagcgagcaa tctcttcttt cttggctcct ggcaagactt
     2401 gaactaggaa accacctgca accttgacct tgtcttcctc gtccaaaagg acattgaggc
     2461 cgaccgctga aggcgtttgt tggctttcag taaggtaaaa ggcaaggtct tcaccgattt
     2521 ctccagagat gaggggagtt atagagttgt aaggatttcc agtaccgtag tctgtgataa
     2581 cgaggaattg accatttcca acaaaaggtc cgactaggac ttcaccagtc gcagtctttt
     2641 tgatgtcaac accaggattt tgaacgtagc ctttgacgtt ccccttggta tcagcgacgg
     2701 tgataatagc acctagagag ctagatccca acaccttaac tgtaagtttg gtatttcctt
     2761 tttcattggc tgcgagaatc tggctggcga taagagttcg accaagcgct acagttgagc
     2821 tagcttgggt ttgatgtttt tcttgagcag tgcggacggt ttcagtgcta tcaaggacaa
     2881 aagcacgaaa ggctccgctt tctgatatag ttttaataat tttatccata gctactattt
     2941 tagcataaaa atgcccaaag ggggagccgt gtgtttactg attttcagga taatggacca
     3001 ggaaatcagc atgaaaataa aaagagaaac agattatttt agcatttgta agatttatgc
     3061 tatgcttaag gtagaaaatg aaaggggtaa caaatgtatt taggagattt gatggagaaa
     3121 gccgagtgtg gtcaattttc aatcctttcc tttctattac aagagtctca gacgaccgtc
     3181 aaggctgtaa tggaagaaac aggattttca aaagcaaccc taaccaaata tgtcaccctg
     3241 ctcaatgaca aggctttgga tagtggctta gagctgacta ttcactcaga agatgaaaat
     3301 ctgcgtctgt ctatcggtgc agctaccaag gggagagata ttcggagctt gtttttggag
     3361 agtgctgtta aataccagat tttggtttat cttctctacc accaacagtt tttagcccat
     3421 cagctggctc aagaattggt gattagcgag gctacgcttg gtcgtcactt ggctggttta
     3481 aatcagattt tgtcagaatt tgatttatcc atccaaaatg gacgttggcg aggtccagag
     3541 catcagattc gctatttcta tttctgtctt ttccgaaagg tctggtcgag tcaggaatgg
     3601 gaaggtcaca tgcagaaacc agagagaaaa caggagattg ccaatttaga ggaaatctgc
     3661 ggtgcaagtt tgtctgcggg gcagaaattg gacttggttc tctgggctca catcagtcaa
     3721 caacgtcttc gggtcaatgc ttgtcagttt caagttatag aagagaaaat gcgagggtat
     3781 tttgacaata tcttctatct tcgtttgctg agaaaggttc cgtccttttt tgctgggcaa
     3841 catattccac taggagttga ggatggtgag atgatgatat tcttctcttt tctcctatct
     3901 catcgcattc ttcctcttca tactatggag tatattcttg gttttggagg gcagttggca
     3961 gatttactga cgcaattgat tcaagaaatg aagaaggtgg aactattggg ggattataca
     4021 gaggaccatg tcacctatga actcagtcag ctttgtgctc aagtctatct ctataagggc
     4081 tatattttac aggatcgcta caagtaccag ttagagaatc gtcatccata tttactgatg
     4141 gaacatgatt ttaaagagac agcagaggag atttttcatg ctctgcctgc ttttcaacag
     4201 gggacagatt tagataagaa gattctctgg gaatggctcc agttaatcga atatatggct
     4261 gaaaacggtg gccagcatat gcggattggt ctggatttga catctggttt tcttgtcttt
     4321 tcaaggatgg cagccatttt gaaacggtat ttggaataca atcgttttat taccattgaa
     4381 gcttatgacc ctagtcggca ttatgatttg ctggttacca ataaccctat tcataagaag
     4441 gaacagacac cagtctatta tttaaaaaac gacttggata tggaagattt ggcagggatt
     4501 cgccagttat tattcactta aaaggcttgg tgcttccagg tctttttgtg aaattcacac
     4561 aatctcctca cattttttta aaaattaaaa aaagttgata aacaagaaag cgctttattt
     4621 tgtatactag taagtgtaaa gaggaaacac ctcaagatct ttatcaggag gacagtacat
     4681 gtcacaagaa aaatatatca tggccattga ccagggaact acaagttctc gtgccatcat
     4741 tttcaacaaa aaaggggaaa aggttagctc gagtcaaaaa gagtttaccc agattttccc
     4801 tcaggcaggt tgggttgagc acaatgccaa tgaaatttgg aactctgttc agtcagttat
     4861 tgcgggtgct ttcatcgaaa gtggtgtcaa gccaaatcaa atcgaggcaa tcgggattac
     4921 caaccaacgt gaaacaacgg ttgtctggga taagaaaaca ggacttccta tctacaatgc
     4981 tatcgtttgg cagtcacgcc agacagcacc tttggctgag caactaaaaa gccaaggtta
     5041 tgtggaaaaa ttccatgaaa agactggttt gattattgat gcttacttct ctgctaccaa
     5101 ggttcgttgg attttggatc atgtagaagg tgctcaagag cgagcagaaa aaggggaatt
     5161 gctctttggt actatcgata cttggttggt ttggaaattg actgacggtg cggctcacgt
     5221 gactgactac tcaaatgcag ctcgtaccat gctttataac attaaagaac tcaaatggga
     5281 tgatgagatt ttggaaatcc ttaacattcc gaaggctata cttccagaag ttcgttctaa
     5341 ctccgaaatc tacggcaaga cagctccatt ccatttctac ggtggagagg tgccaatctc
     5401 aggtatggct ggggaccaac aagcagccct ctttggacag ttggcttttg agccaggtat
     5461 ggttaagaat acttatggaa caggctcttt catcatcatg aatactgggg aagagatgca
     5521 gttgtctgaa aacaacctct tgacaaccat tggttacgga atcaacggta aggtttatta
     5581 tgccttggaa ggttctatct tcatcgcagg aagtgctatt cagtggcttc gtgacggtct
     5641 tcgcatggtt gaaaattcac cagaatctga aaaatacgct cgtgattctc acaacaacga
     5701 tgaagtttat gtcgttccag cctttacagg tctaggcgct ccatactgga accaaaatgc
     5761 tcgtggttcc gtctttggtt tgactcgtgg aacaagcaaa gaagacttta tcaaggcgac
     5821 tttgcaatct attgcttatc aagtgcgtga catcatcgac accatgcaag tggatactca
     5881 gaccgccatt caagtattga aggtggatgg tggtgcagcc atgaacaact tcctcatgca
     5941 gttccaggcg gatattttag gcattgacat tgcacgtgct aaaaacttgg aaacaacagc
     6001 tctaggagcg gccttcctag caggtttgtc agtagggtac tggaaagact tggacgagtt
     6061 gaaactcttg aacgagacag gagaactctt tgagccatct atgaacgaat ctcgcaagga
     6121 acaactctac aagggctgga agaaggctgt gaaagcaact caagtctttg cggaagtaga
     6181 cgactaatac tggcagaata aagcgattta tttagaaagt gtgtaaatat ggaattttca
     6241 aaaaaaacac gtgaattgtc aattaaaaaa atgcaggaac gcaccctgga cctcttgatt
     6301 atcggtggag gaatcacagg agctggtgta gccttgcagg cggcagctag cggtcttgag
     6361 actggtttga ttgaaatgca agactttgca gaaggaacat ctagtcgttc aacaaaattg
     6421 gttcacggag gacttcgtta cctcaaacaa ttcgacgtag aagtggtctc agatacggtt
     6481 tctgaacgtg cagtggttca acaaatcgct ccacacattc caaaaccaga tccaatgctc
     6541 ttaccagttt acgatgaaga tggagcaacc tttagcctct tccgtcttaa agtagccatg
     6601 gacttgtacg acctcttggc aggtgttagc aacacaccaa ctgcgaacaa ggttttgagc
     6661 aagaaagaag tcttggaacg ccagccaaac ttgaagaagg aaggcttggt aggaggtgga
     6721 gtgtatcttg acttccgtaa caacgatgcg cgtctcgtga ttgaaaacat caaacgtgcc
     6781 aaccaagacg gtgccctcat tgccaaccac gtgaaggcag aaggcttcct ctttgacgaa
     6841 agtggcaaga ttacaggtgt tgtagctcgt gatctcttga cagaccaagt atttgaaatc
     6901 aaggcccgtc tggttattaa tacaacaggt ccttggagtg ataaagtacg taatttgtct
     6961 aataagggaa cgcaattctc acaaatgcgc ccaactaagg gagttcactt ggtagtggat
     7021 tcaagcaaaa tcaaggtttc acagccagtt tacttcgaca caggtttggg tgacggtcgt
     7081 atggtctttg ttctcccacg tgaaaacaag acttactttg gtacaactga tacagactac
     7141 acaggtgatt tggagcatcc aaaagtaact caagaagatg tagattatct acttggcatt
     7201 gtcaacaacc gctttccaga atccaacatc accattgatg atatcgaaag cagctgggca
     7261 ggtcttcgtc cattgattgc agggaacagt gcctctgact ataatggtgg aaataacggt
     7321 accatcagtg atgaaagctt tgacaacttg attgcgactg ttgaatctta tctctccaaa
     7381 gaaaaaacac gtgaagatgt tgagtctgct gtcagcaagc ttgaaagtag cacatctgag
     7441 aaacatttgg atccatctgc agtttctcgt gggtctagct tggaccgtga tgacaatggt
     7501 cttttgactc ttgctggtgg taaaatcaca gactaccgta agatggctga aggagctatg
     7561 gagcgcgtgg ttgacatcct caaagcagaa tttgaccgta gctttaaatt gatcaattct
     7621 aaaacttacc ctgtttcagg tggagaattg aacccagcaa atgtggattc agaaatcgaa
     7681 gtctttgcgc aacttggagt ttcacgtggt ttggatagca aggaagctca ttacctagca
     7741 aatctttacg gttcaaatgc accgaaggtc tttgcacttg ctcacagctt ggaacaagcg
     7801 ccaggtctta gtttggcaga caccttgtcc cttcactatg caatgcgcaa tgagttgact
     7861 cttagcccag ttgacttcct tcttcgtcgt accaatcaca tgctctttat gcgtgatagc
     7921 ttggatagta tcgttgagcc agttttggat gaaatgggac gattctatga ctggacagaa
     7981 gaagaaaaag caacttaccg tgctgatgta aaagcagctc ttgctcaaaa cgacttagca
     8041 gaattaaaaa attaagaaaa aataaaagag gtggagggta gcaatccttg tcgcccgccc
     8101 cttcttttta atggagacag aaaaatgatg agtgaattat ttggagaatt tttagggact
     8161 ttaatcctga ttcttctagg aaatggtgtt gttgcaggtg tggttcttcc aaaaaccaag
     8221 agcaacagtg caggttggat tgtgattact atgggttggg ggattgcagt tgcggttgca
     8281 gtatttgtat ctggaaaact cagcccagct catttaaatc cagctgtgac agttggtgta
     8341 gctttaaaag gtgacttgcc ttgggcttcc gttttgcctt atatcttagc ccagttcgca
     8401 ggggctatgc tgggtcagat tttggtttgg ttgcaattca aaccgcatta tgaggtagaa
     8461 gaaaatgcag gcaatatcct ggcaaccttc agtactggac cagccatcaa ggatactgta
     8521 tcaaacttga ttagcgaaat ccttggaacc tttgttttgg tgttgacaat ctttgctttg
     8581 ggtctttacg attttcaggc aggtatcgga acctttgcag tgggaacttt gattgtcggt
     8641 atcggtctat cactaggtgg gacaacaggt tatgccttga acccagctcg tgaccttgga
     8701 cctcgtatca tgcacagcat cttgccaatt ccaaacaagg gagacggaga ctggtcttac
     8761 gcttggattc ctgttgtagg ccctgttatc ggagcagcct tggcagtgct tgtattctca
     8821 cttttctagt ttatactctt cgaaaatcaa attcaaacca cgtcagcgtc gccttaccgt
     8881 actcaagtac agcttgcggc tagcttccta gtttgctctt tgattttcat tgagtattag
     8941 aaaacaatta ttttgataga gcttgggcaa gagcccaatt tcagcaaaaa atgaagtaaa
     9001 tcttctcata ataaaacgca tcatatcaag cacgaaaatt ccacgaggtc aactacagtc
     9061 agaaagctga acaacaagcc aaaacgccca aaaaaggcgg caaaaagcaa gcacctgcaa
     9121 gcaacgtgcc gaaatgatca aatcctgatt atgtcaacga attagaccca aaaatcgttg
     9181 atatgctagt agaatttcac aagtcacaag gcactttgga aactcccgag gcgcaagcag
     9241 aaatcgccca aaaacgtgaa gaaatcgagc aaaggagagc tgagcttgag ggtaaaaaac
     9301 aagagctttt gaaccgcttg aacaaataga gtttcgcaag tattatgctt acaaattact
     9361 tgagcaatta actaaaatat aaaccctgcc tttatatcta ggcagggttt atattttaga
     9421 aattcacgta ggttgttacg gtttttacat acccagtata gtttgagttt ctatagtatt
     9481 cagtgataaa cttccatttt ctttgagcaa catggatata agtacttgtt atgtagtatg
     9541 gatatgggct ttgtgaatcc aagtaagact gataagcttg tataccaaaa tatgctccac
     9601 caattattgc accccatgga cccccaataa agcacctatc ctaccaatca tataactgat
     9661 tccagcacca gtcatgaagt tagcgaatgt gttagcttgt ttattcccat gtattgtgtt
     9721 gacgtaattc caaacattag gatcgtatga tctaaaagat atatttaggt cgatttcatt
     9781 cttttgataa gccatataaa atgccccatt gatatagacg ccgtcagcac gtcgttcaat
     9841 agtgtctaca cttccatctg gattgacaac ctcaagaact tcatcgctta aaatatttac
     9901 ttgcgtatct ccgaaccgca ctgatgagcc attctcaaac tgagcctcac cagatacaac
     9961 tttagagttt gccgataagc tatcatcagc aaaaacaaca agcgacgggg aaatgctaga
    10021 catacagaaa acagacataa ctagcaaaca catgcattta aacatcttag acataacgga
    10081 aactcttttg tatttttgat ttttttcaac ttttattata caataaaacc aaataaaaag
    10141 aaagcggtaa caatatgctt aatgcgaaaa ttttttatat atttttatgt ttgatcgtta
    10201 tcgaaactac aggcttgttg ttgttgaaaa gaggtctcga aatgggttat ttagacacag
    10261 aagctattat cctcgcagtt ttttcatttg ctttttacaa cctatgttca ttcgcttggg
    10321 tctgctctac aataaaaaat aaatagacgt attttcaaaa aaaaaaaatg catatttatc
    10381 ttagcaaaac gacgatttaa atcgtcgttt ttttgtagta cgacgggcat gtcgtatatc
    10441 tgaggtgtaa gtcctcggtg ggcacctgct accggtgaac ccaatagcga ttcccaagcc
    10501 tgactatcgt gaggtagcag ggagaggaag ggatagcgaa atcgtggctc tacgaacagg
    10561 aacgtgatag taaggcgtat atagcggata aggaggcttc aaactctaaa gtccaaaaag
    10621 gtagtcgtaa cctatatgtg taaatcacga gagtaattga attcggacta aggtttgtgt
    10681 gaaaaagata aatctttcta gagtctaaag attctgcgtc agatttccta ttttcactgt
    10741 aaccttttaa cgtcctcata tcttgtataa acgaggaaag atgtacgact tatcccgtga
    10801 ggtttcatga gcgctgaaag cgtagtaaca acgaatcatg agaagtcagc cgagcccata
    10861 gtagtgagga aacttccgta atggaagtgg agcgaagggg tgaatactca aacagtctgg
    10921 ggagagactg tttgaggtct gtcgctagaa agagaaaacg acagatcgaa gtaatcctac
    10981 ttcacttgtg tctgtaaaat gagtggtctg atagaactgg actttgacac gtaatgacta
    11041 gatgaaggtt caccaatata agatgtccct caggcaccaa aacaagaaag gaatacgcac
    11101 atgtcaaaac tgctagataa gatattatca cgcgaaaata tgctggaagc ctacaatcaa
    11161 gtaaaatcca ataaaggctc agctgggatt gatggaatga ctatcgaaga gatggataat
    11221 tatctcagac aaaactggcg cttgactaag gaactgataa aacagagaaa atataagcct
    11281 caaccagttc ttaaagttga gatacctaaa ccagacggag gcatccgtca actaggaatt
    11341 ccaacagtta tggatagaat gattcaacag gccattgtcc aagtcatgag ccccatttgt
    11401 gaaccccatt tctcagatac gagttatggt ttcagaccaa ataggtcatg tgaaaaagcc
    11461 atcatgaagc tcttagaata cttaaatgac ggctatgagt ggatagtgga tatagatcta
    11521 gagaaatttt tcgatacagt tcctcaagat agattgatgt ccttagtaca taacattatc
    11581 gaagacggag atacggaatc cttgattcgt aagtatcttc attcaggtgt tatcattaat
    11641 ggtcaacgtt ataaaacact agttggtaca ccacagggag gaaatttatc tcctctctta
    11701 tccaatatca tgcttaatga attggacaag gaattagaaa agaggggact tcgatttgtg
    11761 cgctacgcag atgattgtgt gattacggtc ggaagcgagg cagcctctaa gcgtgtgatg
    11821 tattcagtca gtcgttttat tgagaaacgg ctaggtttga aagtaaacat gatcaagact
    11881 aagattacca gaccaagaga gttgaaatat ctaggttttg ggttctggaa atcatcagat
    11941 ggttggaaaa tccgtccaca tcaagatagt gttcggagat ttaagtttaa attgaagaaa
    12001 ctaacacaga ggaaatggag tatagaccta acaagacgta ttgagcaact gaatttgtct
    12061 attcgaggat ggataaacta tttctcattg ggaaatatga aaagtatagt cgccagcata
    12121 gatgagcgct tgcgtactcg cctacgagtg attatctgga agcaatggaa gaagaaatcg
    12181 agacgattat ggggattgct taagttagga gttcctaaat ggatagcaga taaggtatct
    12241 ggctggggcg accattatca attagtagct cagaagtcgg tacttaaacg tgctatatca
    12301 aaaccagtcc tggaaaaacg tggactggtt tcgtgtttgg attattacct tgaacgacat
    12361 gcgttaaaag ttagttgaac cgctgtatgc cgaacggcac gtacggtggt gtgagagggg
    12421 ctagagatta tcccctactc gattaactcc cctgaaattt attttaatta tgcaaatttc
    12481 acgtattttt gatgctgaga cgacgatcct gggaactttt cagatatttt tttgactatc
    12541 taaatctatc attagaaaag cttagagcgc caaaggattt gagcgttttt ctgattttta
    12601 agactttttc cagtctcttt ttcgattgaa gatgtaatta ttctactaac taacttctta
    12661 gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata aaggcaatag
    12721 tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat gctaaaatat
    12781 taaaaatcaa atttaattcc agagtttgta actaaagggg gagcgctaca tgtctaattc
    12841 atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt tctttagagt
    12901 aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat cactagttcc
    12961 tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg ttactaaaag
    13021 gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat tattggcgat
    13081 actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct atctatttgt
    13141 tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta ttgtgccacg
    13201 ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg aagctgttca
    13261 attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt tacctaccac
    13321 gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc ttcctaacgc
    13381 tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag gttggaagtt
    13441 agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg aaattttttc
    13501 aaatacgatt tgggtttctt ccattatact tgtttttgta acggagttat taaataaaac
    13561 ggaaagttac tggggatatt ctaatacagc atactctatt ggtattataa ttagtggctt
    13621 aattgctttt aggctatctg aaaagttcct tgctgctaaa tgggaaagta ttctttttcc
    13681 tcttgtagct atggcaatag tgacactgac tattctatat tttccaaacg cacagatgtt
    13741 tttattattt tcagctttag ttggtatgtt atcgcaacta aaagaagttc ctgaaagtgt
    13801 atttcttcag gaaacagtag aggaaaatca tttagttaat gtctattccg ttcttgaagt
    13861 gatttctaca ttagcatttt cagtatttgt tttgctaatg agctatatta ctgagagttt
    13921 tggtattagc atcagttttt ggctatcagc catttgtctg atgatagaag ctattttaat
    13981 ttatatcaga cgagattatt ttaaatgaga gagtggttaa aaagtcttta aaaatcagaa
    14041 aagcgcatag tatcaggtgt tgaaaaaact tgatattgtg tgttttatta tgggaagatt
    14101 tacttcattg tctcctgaaa tggagttttg aagcaggatc actctatttg aaaatataca
    14161 tagaaaaacc gcataatcct taaaataagc tgaaatctat tggaaacata cggtaaacaa
    14221 ttgaaaagat actatataaa gtggtacaat ggtagaaaaa taagctagta agaatcactc
    14281 ttattttagc gaaaaattac agaaatgaat ggtttttctt gatgaaacag agaaaagaat
    14341 tgtacctctt tcttggtcgg acagccttgt attttcttat ctttctaggg ctgctttact
    14401 tctttagcta tcttggtcag ggtcaaggaa gctttatcta taatgaattt taacttgaag
    14461 gagaatccct attgtgtcaa ataaaccaat agcagatatg attgaaacca ttgagcattt
    14521 tgctcagaca cagcctagct atcctgtcta taatgttttg gggcaggaac acacttatgg
    14581 cgatttaaag gctgattcgg atagtttggc tgcagtcatt gaccaactag gcttgcctga
    14641 gaagtctcct gtggttgttt ttggtggcca agaatatgaa atgttggcaa cctttgtagc
    14701 gctgactaag tcaggtcatg cctacattcc aattgatagc cattcggcct tggagcgagt
    14761 ttcagctatt ttagaagtag cagagccaag cttgattatt gccatttcag cctttccctt
    14821 ggagcaggtt tctacaccaa tgataaatct agctcaggtt caagaagcct ttgcccaagg
    14881 gaacaactat gaaatcacgc atccagtcaa gggagatgat aattactaca ttatctttac
    14941 ttctggtacg actggtaagc ctaagggagt gcagatttca catgataatc tcctcagctt
    15001 tacaaactgg atgattacgg ataaggaatt tgcgacaccg agtcgtccgc aaatgctggc
    15061 acagccacct tattcttttg acttgtctgt catgtattgg gcaccgacct tggcacttgg
    15121 tggtacgctt ttcactcttc cttcagtcat cactcaggac tttaagcaac tctttgcggc
    15181 tatcttttca ttgccaatcg ctatctggac atcaacacca tcctttgcag atatggccat
    15241 gttgtctgaa tacttcaaca gtgagaaaat gcctggaatc acgcatttct actttgatgg
    15301 tgaagaattg acggtcaaaa cagctcaaaa actgcgcgag cgtttcccaa atgcccgtat
    15361 catcaatgct tacggcccaa cagaagcgac agtagctctg tcagcagttg ccgtgacaga
    15421 cgagatgtta gcgactctca aacgcctacc aatcggctat actaaggctg attctccaac
    15481 ctttatcatt gacgaggaag gaaataaact gccaaatggt gagcagggag aaatcattgt
    15541 ttctgggcca gctgtttcaa aaggttatat gaacaatcct gaaaaaacag cagaagcctt
    15601 ctttgagttt gaaggtctgc cagcctatca cacaggcgat gtgggaacca tgacagatga
    15661 gggcttgctt ctctacggcg gacgcatgga cttccagatt aagtttaacg gttaccgcat
    15721 tgagttagaa gatgtctctc aaaacctcaa caagtctcgc tttatcgaat ctgctgtcgc
    15781 agtaccgcgc tataacaagg accacaaggt acaaaatcta ttggcttatg tcatcttaaa
    15841 agacggtgtt cgtgagcagt ttgagcgaga tatcgatatt accaaggcca tcaaggaaga
    15901 cctgacagac atcatgatgt cctatatgat gccatctaaa ttcctttacc gagacagttt
    15961 gccactaact ccaaatggaa agattgacat caaaggattg attaacgagg tgaataagag
    16021 atgatggagt tttttcaaca gcttcctcat ttagagccat atggcaatcc tcagtatttt
    16081 gtttatgtga ttgctgcaac cttgcccatc tttataggtc tctttttcaa gaaacgcttt
    16141 gcctggtatg aagtgttggt aagtctcttc tttattgtca ccatgttggt gggtggaaag
    16201 accaatcaac tagctgcctt gggtatttac ctttgctggg aaatattgct cctgcttttc
    16261 tacaagcatt atcgaaaaag caaggatggc aagtgggtct tctacttagt tagttttctg
    16321 tccctacttc cgattatctt tgtcaaggtg caaccagcta tcaatggaac gcagtctttg
    16381 cttgggttct tgggaatttc ttaccttacc tttcgttcgg ttggaattgt catcgagctg
    16441 agagatggag tgattaagga ttttaccctc tgggaattcc tccgtttcct tctcttcatg
    16501 ccaactttct cgagtggtcc aatcgatcgc tttaagcgat ttaatgaaaa ttatcaggct
    16561 attcctgagc gagatgagtt gatggatatg ctggatgaat ctgtccgcta tatcatgtgg
    16621 ggctttttgt ataagtttat cctagctcat gttttaggag agaccttact acctcctctg
    16681 aagaatttag ccttgcagtc aggtggcttc tttaatctct atgccttggc agttatgtat
    16741 acttttggtc tggaactctt ctttgacttt gcaggttatt ctatgtttgc tttggccatc
    16801 tcaaacttga tgggaatccg tagccctatc aactttaaca agcccttttt atcaagggat
    16861 ttaaaggagt tttggaatcg ctggcatatg agtctgtcct tctggttccg tgactttgtc
    16921 tttatgcgaa tggtgatggt gttaaccaga aagaaagtct ttaaaaatcg taatgtaacc
    16981 tcaagcatgg cctacattgt aaatatgctg attatgggat tttggcatgg cgtgacctgg
    17041 tactatatcg cctatggact ctttcatgga ctaggcttgg tcatcaatga tgcctgggtt
    17101 cgcaagaaaa aaacgctcaa taaggaacgg aaaaaagcag ggaaggctgc cctacctgag
    17161 aatcgctgga ttcagtttct tggcatggtt gtcactttcc atgttgtcat gttgtcattc
    17221 ttaatctttt ctggattctt gaataatcta tggtttaaaa aataaaagga aataaaatat
    17281 ggatatcaaa tcagaagtta ttgaaattat tgatgagttg tttatggaag atgtttctga
    17341 catgatggat gaagatcttt ttgatgcagg tgtcttggat agtatgggaa cggttgagtt
    17401 gattgtggag attgagaacc gttttgacat tcgtgtccct gtaacagagt ttggtcgtga
    17461 cgactggaat acagctaata aaatcatagc tggtattgtg gagctacaaa atgcttaaac
    17521 gcttatggat gatcttcgga ccggtcttga tcgctggttt gttggttttt ctgctcattt
    17581 tcttttatcc tactgagatg catcataatc taggagctga aaagcgttca gcagtggcta
    17641 ctactatcga tagttttaag gagcgaagtc aaaaagtcag agcactatct gatccaaatg
    17701 tgcgttttgt tcccttcttt ggctctagtg aatggcttcg ttttgacggt gctcatcctg
    17761 cggtattagc tgagaaatac aatcgttcct accgtcctta tcttttagga caggggggag
    17821 ctgcatcgct taaccaatat tttggaatgc aacagatgtt accacagctg gagaataaac
    17881 aagttgtgta tgttatctca cctcagtggt tcagtaaaaa tggctatgat ccagcagcct
    17941 tccagcagta ttttaatgga gaccagttga ctagttttct gaaacatcaa tctggggatc
    18001 aggctagtca atatgcagcg actcgcttac tgcaacagtt cccaaacgta gctatgaagg
    18061 acctggttca gaagttggca agtaaagaag aattgtcgac agcagacaat gaaatgattg
    18121 aattattggc tcgttttaat gaacgccaag cctccttttt tggtcagttt tcggttagag
    18181 gctatgttaa ctacgataag catgtagcta agtatttaaa aatcttgcca gaccagtttt
    18241 cttatcaagc aatagaagat gttgtcaaag cagatgctga aaaaaatact tccaataatg
    18301 agatgggaat ggaaaattat ttctataatg agcagatcaa gaaggatttg aagaaattaa
    18361 aggattctca gaaaagcttt acctatctca agtcgccaga gtataatgac ttgcagttgg
    18421 ttttaacaca gttttctaag tctaaggtaa acccgatttt tatcattcca cctgttaata
    18481 aaaaatggat ggactatgct ggtctacgag aggatatgta ccaacaaacg gtgcagaaga
    18541 ttcgctacca gttagaaagt caaggtttta ccaatatagc agatttttct aaggacggcg
    18601 gggagccttt ctttatgaag gacaccattc accttggttg gttgggttgg ttggcttttg
    18661 acaaggcagt tgatcctttc ctatccaatc ccacaccagc tccgacttac catctgaatg
    18721 agcgcttttt cagcaaagat tgggcgactt atgatggaga tgtcaaagaa tttcaataga
    18781 taatataata tagaagagtt caagaatgaa actagttttc acgttttttc ttgactcttt
    18841 ttttgcttgt gatataatta actggtaaac aaaatgtcaa agaatagtat ttttctctta
    18901 aaaaagagaa gtctaaaagg aaaggagtca gatatgagac agctagcaaa ggatatcaat
    18961 gcttttttga atgaggtgat tttgcaggcg gaaaatcagc atgaaatcct aataggtcat
    19021 tgcactagcg aggtggccct gaccaatact caggagcata tccttatgct cttgtcagag
    19081 gaatctttaa caaattcaga attggcccgt cgtctcaatg tcagtcaggc ggcagttacc
    19141 aaggccatta agtctttggt caaggaaggg atgttggaaa catctaaaga ttctaaagat
    19201 gcgcgtgtga ttttttatca gttgactgac ttggctcgtc caatcgctga ggagcaccac
    19261 catcaccatg agcatacact tttaacctat gaacaagtgg cgactcagtt tactccaaat
    19321 gaacaaaaag tgattcagcg gtttttgact gctttagtag gagaaatcaa ataatgagat
    19381 atattacggt agaggatttg tccttctatt atgataagga gcctgttctt gaacatatca
    19441 attatagtgt tgatagtggg gaatttgtta ccttgactgg ggaaaatgga gcggctaaga
    19501 cgacgctcat caaggccagt cttggaattc tgcaaccacg cattggaaag gtggctattt
    19561 caaagacaaa tacgcaaggt aagaaattga gaatagccta tcttcctcaa caaattgcca
    19621 gttttaatgc tggttttcca agtacggtct atgaatttgt caagtcgggt cgctatccga
    19681 gaaaaggctg gttccgtcgt ttgaatgctc atgatgagga gcatatcaag gctagtctgg
    19741 actcagttgg catgtgggaa catcgagaca aacgcttggg gtctctatct gggggacaaa
    19801 agcagcgagc ggtgattgcg cgtatgtttg cttctgaccc tgatgtgttt atcctagacg
    19861 agccgacaac ggggatggat gcaggaagta aaaatgaatt ttacgaactc atgcaccaca
    19921 gcgcccatca tcatggcaag gctgttttga tgattaccca tgaccctgaa gaagttaagg
    19981 attatgcgga tcgcaatatt catctagtcc gtaaccaaga ctcgccatgg cgttgtttca
    20041 atgttcatga gaatggccag gaggtgggcc atgcttagtt tattatctta cgactttata
    20101 caacgcgcct ttttggcggt tattgctatg agtcttttct caccggtatt gggaaccttc
    20161 ctcatcttgc gtcgtcagag tttgatgagt gataccctta gccacgtctc actttcaggt
    20221 gtagcctttg gtctggtttt ggggatttct ccaactgttt ctactattgc cattgtcttg
    20281 attgcggcgg tctttctgga gtatctccgt acggtttaca agagctttat ggaaatcggg
    20341 acagctatcc tcatgtcaac aggtctggct gtttctctga ttgtcatgag caagggtaaa
    20401 agctcgagtt caatgagttt ggaccaatat ctctttggtt cgatcgtgac tatcagtgaa
    20461 gaacaggtca tttccctctt tgtcattgcg gcggttgttt tgattttgac ctttctcttt
    20521 cttcgtccta tgtatatctt aacttttgac gaagatacgg cctttgtgga tggcttgcca
    20581 gttcgtacca tgtccattct ttttaacatg gtgacagggg tggctattgc ccttatgatt
    20641 cctgcagcag gagctcttct ggtatcgacc attatggtct tgccagctag tattgccctg
    20701 cgtctgggga aaaactttaa atcggttatg ctgcttgcca gtgcgattgg ctttttggga
    20761 atggtagcag gactttacat ttcctactat gcagaaacac ctgcaagtgc aagtattacc
    20821 attatttttg taactgtctt tatactaatc agtttagtaa gacgttttat caaataggag
    20881 acgaacgtga aaaaaattag cttattacta gccagtctat gtgccttgtt tttagtggct
    20941 tgttccaatc aaaaacaggc agatggtaaa ctcaatatcg tgacaacctt ttaccctgtc
    21001 tatgaattta ccaagcaagt tgcaggagat acggctaatg tagaactcct aatcggtgct
    21061 gggacagaac ctcatgaata cgaaccatct gccaaggcag ttgccaaaat ccaagatgca
    21121 gataccttcg tttatgaaaa tgaaaacatg gaaacatggg tacctaaatt gctagatacc
    21181 ttggataaga aaaaagtgaa aaccatcaag gcgacaggcg atatgttgct cttgccaggt
    21241 ggcgaggaag aagagggaga ccatgaccat ggagaagaag gtcatcacca tgagtttgac
    21301 ccccatgttt ggttatcacc agttcgtgcc attaaactag tagagcacat ccgcgacagc
    21361 ttgtcagcag attatcctga taaaaaagag acctttgaga agaatgcagc tgcctatatc
    21421 gaaaaattgc aagccttgga taaggcttac gcagaaggct tgtctcaagc aaaacaaaag
    21481 agctttgtga ctcaacacgc agcctttaac tatcttgcct tggactatgg actcaaacaa
    21541 gtcgcaatct caggactttc tccagatgca gagccatcag ctgctcgctt ggcagaattg
    21601 acagagtatg tcaagaaaaa taaaatcgcc tatatctatt ttgaagaaaa tgcctcacaa
    21661 gcccttgcta acacactttc aaaagaagca ggtgtcaaaa ctgatgtcct caatccttta
    21721 gaaagtctga cagaagagga caccaaggct ggagaaaact acatttccgt gatggagaaa
    21781 aacctcaagg ctttgaaaca aacaacagac caagaaggcc cagcaatcga acctgaaaag
    21841 gcagaggata ccaagacagt ccaaaatggt tacttcgagg atgcagctgt caaggaccgc
    21901 accttgagtg actatgcagg taactggcaa tcagtttatc ctttccttga agacggcacg
    21961 tttgaccaag tctttgacta caaggctaag ttgactggta agatgaccca ggctgagtac
    22021 aaggcttact atacaaaagg ctatcagaca gatgtgacta agattaacat tactgataat
    22081 actatggaat ttgttcaagg tggacaaagc aagaaataca cttacaagta tgtcggtaag
    22141 aaaattttga cttacaagaa aggcaatcgt ggcgtgcgtt tcctctttga agccacagat
    22201 gctgacgctg gacaattcaa gtatgttcag tttagtgacc acaatgttgc cccagttaag
    22261 gcagaacatt tccatatctt ctttggaggc acaagccaag aagccctctt tgaagaaatg
    22321 gacaactggc caacctacta cccagataac ctatctggcc aagaaatcgc ccaagaaatg
    22381 ttggcgcatt gatgagaaat cgactagttc ataagagcta gtcggttttt tgatactaga
    22441 tggctaactt cattatagac ctttcagaac tttaaacaat aaataaaact cttgaaatat
    22501 ctgggcttat atgctagaat gtagttagtg tataaggttc attagaacac caaagcccct
    22561 aactagtgcc atagttaagg gcttttttga cgtatcttag cgatttaacg ggtgtttata
    22621 ggctagtcag tcggtctact tcttaccatc tagccatttg cagacgaaat acaagataat
    22681 tccagctata acatctgcta taatagtaag agcaagctct ggtataaggc tcattagttt
    22741 cacctcctct cacgaaccca taggaacgta atcggtaacc gatgacaaaa atagtatacc
    22801 acactaaatt tagatcatca acctcactta atgcttgaac tattgtagat tatatgctaa
    22861 aatgtagtta attgataagg ttcattagaa caccaaagcc cctaactatg gccgtagtta
    22921 agggcttttt tgacgtatct tagcgattta acgggtgttt ataggctagt cactcggtct
    22981 actccttact atctagccat ctgcagacga aatacaagat aattccagct ataacatccg
    23041 ctataatagt aagagcgagc tctatgataa ggctcattag tttcacctcc tctcacgaac
    23101 ccataggaac gtaatcggta accgatgaca aaaatagtat accacaatat atttagatca
    23161 tcaaggtcac ttaattcttg aaatataggg tctaggcgac aaagtcttta aaatcagaaa
    23221 aacgcataat atcaggtgtg caaaaacttg atactatgcg ttttattgtg ggaaggttta
    23281 ctccattttc tcctgaaatt gagtttttgt ccagcctctg tttttagaat tgctaagaaa
    23341 ataatgtcat gtggtgaata tttgtaaatc agtcagcaga cagaacgaat actcttcgaa
    23401 aatctcttca catcatgtca gcttcgtctt tccgtatata tgtgactgac ttcatcagtt
    23461 ctatctacaa cctcaaaaca gtgtttcgag ctgacttcat cagttttcaa atctgtactt
    23521 tgagcaagct gagactagct tcctatttga ttttcattga atatcagaaa cccattctcc
    23581 atcaaataat tcgactgcgt ctaataattt ttgatctggc acggtgtctg aaataaaggt
    23641 tgtgtatttg gagaggggat taattttaaa aaatccagtc ttgtaaaatt tagaactatc
    23701 aatcagtaag atggtttcat gggctttgtc aataatattc ttttttgaaa tagcttggct
    23761 gagagaagct tcataaacat attggtcatc aatacctctt gctgaacaaa atgctaaatc
    23821 gatattaaaa tgatctaata aagaattttc cttatcatag ttgaccacgg aacaggattg
    23881 atgtttgacc tcgccagatg tgataaagat tttggagcta tctttaacag tttcagatag
    23941 ggtttgtgca gtatgtaaac catttgtaaa aataatcaaa ttatcaagtt cagaaagata
    24001 gggacagagt tcgtagacag tcgtactgga atccagatag atacacatac cagaccgaat
    24061 aaagtcttta gcgagactag cgattagtct tttttgccta gtactttctc cttcacgtat
    24121 ttgatgagaa agttcaattg tgttcataga ggacagggtc acgtatccgt gctttctttt
    24181 gataagacct tgattttcta agaaaattaa atcacgacgt aaggtacttg tgctggagaa
    24241 agtgatttct gccagctctt ttacggcaat tctttttttc tttttaataa tttcaatcaa
    24301 ttcaagtaca cgttcatctt ttatcataag ctcctcctaa tttatcattt caactatatt
    24361 atagcacaaa ttggaggaat ttgaattatt tttatgaata ttgggttaac atttaaacat
    24421 tattcaagta agcgttcaca tattgaaaaa ataaaacgtg gggattataa taaagttaat
    24481 caaggacgaa gagagaagaa aaatggaagc ggttttagca atagatttag gtgcgacttc
    24541 tggaagagca atcgttggtt acctttctga aaataaacta gtaatggaag aaataaatcg
    24601 cttttctaat ctacctatta gagtaaaagg gcatttatct tgggatattg actttctact
    24661 agctaaaatt cttgaaagta tccgcttggc taatactagt tacaagattt tatctatcgg
    24721 tattgacaca tggggagttg attttggact gattgataat gaaggtaagc tgttattaca
    24781 acctgttcat tatcgtgatg aaagaacaaa gggagtgtta aaggaaatat ctgaaatgac
    24841 tgaattagaa aaactgtatt cagagacagg aaatcagatt atggagataa ataccttgtt
    24901 tcaactcttt aaggcacgtc aagaatctcc tgactctttc tataagacca ataagattct
    24961 tttaatgcca gatttgttta attatctctt gacaggtaag tttgctacag aaaaaagcat
    25021 tgcttcaaca actcaattat ttgatcctag gagtcaaaat tggaatcaga atatcttaaa
    25081 actatttgaa ttggattcaa ctttacttcc tgaaattgtt tcagagggaa atgtccttgg
    25141 aaggataaaa gaggagtatg gtttaggcga tattcctgtt gtgaatgttt gtagtcatga
    25201 tacagcaagc gcgattgtct cagtacctaa gacagaagat agtttgttta tttcatcagg
    25261 gacttggtct ttggttggag tggagctttc ttcacctatt cttagtaccg aatccttcag
    25321 ttatggattt acaaatgaag tcggtaaaga tggagtgatt acatttctga agaattgtac
    25381 agggttgtgg atcatagagg aactaagacg ttcatttgaa cgaagaggga aagcctattc
    25441 ttttgatgat attaggacaa tggtggagaa agaaaaagaa aatcttcctc tgattgatac
    25501 tgaatcaact gaatttgcaa cagaatctga tatgtacaag actttgacag aatatctagc
    25561 ttatcatcat gaaactggag agtggacaga tggacaacta tttaagatcg tttatgaaag
    25621 cctagctgaa acgtataagg aaacaataga gttactagaa gaactaactc ataaggttta
    25681 taagaggata tatgtgattg gaggaggtgc tagagccagt tactttaacc aaatgattgc
    25741 tgatagaact ggtaaagaag ttcttacagg ttcaactgag gctacagctg tggggaatat
    25801 ttgtatacag ctattaagtc aaggtaaaat aaacgaggat acagggttaa aggatattat
    25861 gacaaatatt gctgatacac aatattatta tcctcagcta tcataaacaa aaataaaaaa
    25921 acggaggttt tgtcatgaac aaaaaaagtc ttttgaaatg cgctgttatc gggttagtag
    25981 ctacctttgg tttagcagct tgtggaacat ctaaggatgc aagcggtgga agttcttctg
    26041 gtaaagaagt attagaattt tatcatgggt atcatcatag tgaagatgaa tggcctgtag
    26101 cgaagactat gcgagattta tatgataaat ttgcagaaga acataaagat agtggtgtag
    26161 aatttaaacc aactcctgta aatggtgatt tgaaggatat aatgaataac aaggttgcta
    26221 gtggtgaatt tcctgatgtg attgacctag caggtaatgc agtatcatta gctgcgattg
    26281 aacaaaaact tgttttagat ttgaaaccat atatcgattc aaataagctt gaaaaaaatg
    26341 ttggtttgaa ctataaacaa aaccaaaaag atggaaaaat ttatacagtt cacgaacagt
    26401 tatttacaat gggtctgtgg tacaacaagg acatatttgc aaaagcaggt gctaagacac
    26461 ctgatcagtg gaatacttgg gaagatttta cacaagcaat ggctgctgtg agaaaacaag
    26521 atggagtgta tgcatttggt gctggagaac catctattcg cttgtttaat acagtcttag
    26581 gaaccacaga aaatgggcgt aaattattag acaaaccatt aacaaaagaa ggaattgaat
    26641 ctaaagaatt tgcagatgct ttgaagatgg tcatgaaaga aattcaagct aatggttcta
    26701 agaatgctgg tggcgatgct aatgcgtatt ctaaagactt ccaagaaggt aaatctgcag
    26761 tcttctttaa tggtgtgtgg gcttctggtg agatgtctaa gaacccaagt cttgcacctg
    26821 gaatctatcc tgcaggtgta gcaattagtt cttctggagg tggtatcact atctcaagta
    26881 agatgtctga agctaaacaa aaactagctc ttgagttttt gaaatatatg actagcgatg
    26941 atgtacaaaa agtaattttt gaaaaagtag gagcaaatcc ttctaatgaa aatgtaaatg
    27001 taaaagaact ttcagaaaag agttcagaag ctactactaa aattttagga caagcaatca
    27061 ctcaagttaa gaatgcaaaa gcagttgttc caactgtaag tgatgtttgg ggtggcgatg
    27121 tacacacagc tattatcaat gcattgacag aaagtgctgc tgaaaatgta gatgttgatc
    27181 aaaaagtaaa atctactcaa gatgtgttga aatcattgat tggttaattg ttttagggag
    27241 tgaaaacgaa gctcagttgg cactgccaac tgagcttgat tttacttata tagttgaaaa
    27301 aaggagtttg tttatggcac aaaaaattat gagcctacaa aataggaaga atcaaaaaag
    27361 acgatttatc tttttatttc ttttgccaac gttgatttgt ttctttctat tttattttta
    27421 ttctgtagta acaatctttt taacttcatt tgctaaatgg gattatacaa atttaaacac
    27481 ccctgagttt cttggatttg ataaattatt tgaaaattat aggtatgttt ttaaagaata
    27541 cccatttttt acagaagctc taattaattc tgttcgttgg gctgtaattg gtgttattat
    27601 tcaagttcct ttagctgtat ctgttgcaat tacattatct aagaaattaa aaggctggaa
    27661 gatatctagg aatctttata ttgtaccaag tatcatttct agtgctgcta tgggcttgat
    27721 ttttcttcaa atctataatc caaactatgg tgttgttaac caaattattc atctatttaa
    27781 tccatcgttt aaagattcag tactgttgac tccaggatta aatatagtag ctatgactgg
    27841 cgcttatatc ttctttgcag gagcatcaac cattatgatt cttgggcaaa tttttgctat
    27901 tccagaagaa gttcaagaag ctgctatttt agacaatatt actggttgga ggaaagagtg
    27961 gtatattacg attccgatga ttaaggggac aattaaaact gtttcaatta tggcagcaac
    28021 ttcaggattt ttgctctata acgaagtatt ctttttgaca aatggtgctg caggaacaaa
    28081 aagtatcagt tttgttattc gagaattagc agtggctagc tcacgaactc agtatgctcg
    28141 tgcaaataca attggagtta tacaaatctt aggtggaatg ttgattatcg tttgtattaa
    28201 tattttattc agagaaagaa aaagactgaa aggtgggaaa tgattatgaa tacacatata
    28261 aatggtatta gtaaaaaagg caaagttctt atatatggtt atatgctcct taccatttta
    28321 atttctattt tccctattgc gtggattttt ttatcatcat taaaagcaga tcctatgaaa
    28381 aatccaggta ttagtttacc gactgacttt actcttgaag gttatataaa tgtttttaca
    28441 aaacttcatg ttttcactta cttttggaat agctttaaag tagtgtctat atcagttatt
    28501 attagcattg ttatgatctc catgtcttca tatgttattg ctaggatgga atttagaggg
    28561 aagaagttgg tgacttctat gctgtattct actctattta ttccagcaac agctatgact
    28621 tttccagttt atagattagt aaatgagttg gggatttata ataccccagt tgctctaatt
    28681 ctggtctact cttgtagtgg aattgctatg agtttcttta ttataaagaa ctattttgaa
    28741 attattccaa aagaattgga ggaggcagca gagattgatg gtgcgacata tgctcaaact
    28801 ttttggaaag tgatgttgcc aattgctaga ccaggaattt taacagcagc agtacttgcc
    28861 tttattaata actggaatga atattattgg gcatctatgt tggtgattga taaaaatgaa
    28921 ttaacagtac cagcattact aggtcaattt actacaagtt ttaatactaa ttataatggt
    28981 ctattttcag ctattgttgt aatcgtatta ccaccaatca ttctattcgc atttacaagt
    29041 aaatacttca ttgaagcttt aggaggagga gcagtaaaag gatgaaacat acacttgaaa
    29101 ctatcaatag tagaactcag tggtttagag aagcaagatt tgggatgttc attcattggg
    29161 ggttatattc tattccagga aaaggggaat ggattcgtag tcatcagaaa ttatctattg
    29221 aagattatga accatatttt cgagcttttg atcctaagga atataaccct agagaatggg
    29281 ctaaacaagc aaaagctgca gggatgaagt atatggtttt aacggctaaa catcatgatg
    29341 ggttttgttt gtttgattca aaatttacag attataaagc aacaaataca cctgcaggta
    29401 gagatttagt taaagaattt gtagatgctg ttcgagctga aggtttaaaa gtaggcttat
    29461 attttagttt gattgactgg caccatcctg atttccctaa atatgctgat ctaaatcatc
    29521 caatgagagg aaatgaagcc tatcgagatg agaaaattaa ctttgacagt tatttggagt
    29581 atttgcacaa tcaagttaaa gaaattgtaa ctggttatgg tcagattgac atattatggt
    29641 ttgattattc ttatgaagac atggtgggtg aaaaatgggg agcttcaaaa ttaatagaca
    29701 tggttcgtca ttatcagcca aacgttatcg tagataatag attagaaaca tcaggtgaag
    29761 gattcggaag tatcgttaca gatgaaatta cctcttacgc tggagatttt gttagtccag
    29821 agcaaattgt tcctcacgaa ggtattcgaa actttaaagg tgaacctgtt ccttgggaac
    29881 tttgtctaac tatgaataac aattgggctt ataatcctac agattatcta tataagtcta
    29941 gtcaaacttt gataagaaag ttagtggaat gtgttagtaa aaacggaaat atgattctta
    30001 atgtaggccc agatgctttg ggaagaatta atgattcaag taagaaaata ttagataatt
    30061 ttcatcgatg gatgtctcga aatggtgagg caatttatgg atgtagtgga gatgaaaatt
    30121 taccaaaacc agattgggga tactatactc gtaatggaaa tacggtttat gctcatgtat
    30181 ttgaacaacc tataggtcct ttagctcttc ttggtattag taaagaaaac gtaaaaagaa
    30241 tgagctttct tcatgatgga agtgaggtga aaatttcaga aagctggacg accaatgcct
    30301 acaaaggaat ttgttttgca cagtttggag aagttccaca ttttacctat ccattaccag
    30361 acttgattga tagcgtaatc aaaattgagt tgagagagta gtttatatga aaattgaaaa
    30421 taaaaatgta agacgtaatt tcttttgggg agatggtcga ttttatacta ctgatatcgt
    30481 aaacaaacgg gcaggagtaa tgatagaaaa tgtttcgaaa gaagaattta ccattacatt
    30541 ggagaatggt ataagacttt cttcaaatca tttttcagca atcgttaggg aagagggaga
    30601 tacgcgaatt caggtttctt ttgtttgtcc ttcccttcgt ttacgtttaa tctttgaatc
    30661 gagggatgat gttctttcga agcaattagt tttagaatca tctactgagg ttattaaatc
    30721 tgtagaggta gagagttttg agtttgaaac agaagacaat attttctatc cgaaaagaca
    30781 agattgtatt aaggaaatgg cgaatttttc cggttattat gtagaattgg gacaacctgt
    30841 ttatgcgaat tctttattct taggaatgga atttccaatg tctgaaaaca aggtagatgg
    30901 tagacactat gtatcaagat attacttggg aactgttgta aatcaagaaa agagtttgtg
    30961 gtcttgtatt attgggggag catgttctta taaaaaagaa gagattcaag aggcattttt
    31021 tgaatatgtt gaaggaatag ctcaacctag ttatttccgt aaacagtata attcctggta
    31081 tgaccatatg accgatatta cagaggaagg tattttaaaa agtttttctg agattcgaga
    31141 tggatttgaa aatcatggag ttcatttaga tgcttatgtt gttgatgatg gttggacaaa
    31201 ctatcaatca gtttgggaat tcaatcataa attcccaaat ggtttgagaa atattaaaca
    31261 tcttgtaaat ggatttggtt caagcctagg attgtggatt ggtccccgag gtggttataa
    31321 tgggacagaa atcattatga gtgattggtt agaagcacat ccagagttaa atattggatc
    31381 taaaaatttg atttcaaatg atgtaaacgt ggctgatttt aactatctca atcaaatgaa
    31441 gaaaaagatg ttggaatatc aaaaagaatt cgatatcagc tattggaaaa ttgatggctg
    31501 gttacttcaa cctgacaaac ctgataagag tggaccgcac ggtatgtata ccatgacagc
    31561 ggtttatgag ttcttaattc aactgttgat agatctaaga aaggagagag gaggaaaaga
    31621 ttgttggtta aacttgactt cttatgtaaa tcctagtcca tggtttttac agtgggtcaa
    31681 tagtttatgg attcaaatat ctcaagatgt aggctttaca gagaatgcag gtaatgatat
    31741 caatcgtatg attacttacc gagatagtca gtatcaagaa tttttggaaa aacgtgagat
    31801 acagttacct atgtggtcgc tttataatca tgaaccaatc tatgctgtca gtgcaaatac
    31861 ctggtacatg gatcatcaaa tgtttgcatc aataccagat tttgaagctt atctattatt
    31921 tatttcaaca agagggaatg ctttttggga gtttcactat tcttttgata tgtttgatga
    31981 agaacgctgg aaagccaatg ctcgtgccgt caaatggata gaggagaatt atcaaacact
    32041 aaaatatagt aaaaaaatag gaggaagtcc tgaaaaattt gaaatttatg gttataagtg
    32101 tcacaatcag aagacttcta ctgaaattct ctctctgaga aatcctgctc agattaaaca
    32161 aaaaataaaa atagagaatc tttcgataga gaattttacc agagtaattg gagattttac
    32221 tattcaagaa gatgagatag aattggcacc gtactctatc gtgatactga agaagtaaag
    32281 aaaaaattgt gaggtagaga tgacgattta tattaataag gacgagaccg tttttcattt
    32341 ggcaatgaaa gatagtagtt atatttttag aattttagaa aatggggaac ttcaacatct
    32401 acattttggg aaaaggattc atgtcaagga aaattataac caattgatgg cctatgaaaa
    32461 aagaggattt gaagtatctt tttctgaaga atttgaggat attcaacagt ctatgataca
    32521 aaatgaatat tcttcatatg ggaaaggaga ttttcggcat ccagcctttc aagttcaagg
    32581 aatgaatggt agtaggataa cgacactaaa atatcaaggt tttgaacttg aaaaagggaa
    32641 aaatcgtctt aactctctac cttcaacatt tgatgatatt ggtcagtgtg cggaaacatt
    32701 aacgattatt ttaacagatt ccatattaga tttaactgtt agactaaatt acacaatttt
    32761 tccggaatac aatgtcttag ttagaaatac ggaattttta aataatagca ataataagtt
    32821 gactcttttg aaagcaatga gcttacagct agatctacct gatagtcaat atgactttat
    32881 tcaattttct ggagcatggc tgagggaacg tcagttatat agaacttcgc ttagaccagg
    32941 tattcaagca atagatagct tgagatactc atcaagtcct cagcaaaatc ctttctttat
    33001 gctatcaagg agggaaacta cagagcatag tggtgaggtt tatggtttta actttatcta
    33061 ttctggaaat tttcaaaata tgattgaagt tgaccatttt gacaccgcta gagtaacggt
    33121 aggaataaat ccagtagaat ttcgtttttt attaaatcct gccgaaagtt ttgtgacacc
    33181 agaagcaatt gtgatctatt ctgatcaagg gatgaatcag atgagccaac aactatcaga
    33241 tttttatcga catcatttag ttaatcctaa tttttctcaa gctagtcgtc ctataatact
    33301 caatagttgg gaaacatttt attttgactt gagtacagaa aaaattttag atttagcaaa
    33361 ggctgctaaa gatttaggga tagaattatt tgtactggat gatggttggt ttggtcatag
    33421 gaaagatgac aaaagttctc tgggtgattg ggtaacagat agaagtcgcc ttcctgaagg
    33481 tattggattt cttgcagatg aaattcacaa aataggttta caatttggtt tgtggtttga
    33541 gcctgaaatg atttctattg atagtgattt gtacaagaat catgccgatt ggactatcca
    33601 tttgttagac agagagaagt cagtaggaag aaatcaatat gtgttggatt tgacgagaca
    33661 ggaagttgtt gattatcttt ttgattctat ttctaaaatc ataatcaaaa caaatctgga
    33721 ttatatcaaa tgggatatga atcgtcatat aacagatatt tatagtattg aacttgattc
    33781 tgaacagcag atggaatttg gtcatcgata tatcttaggt ctttatcagt tattagatcg
    33841 tttaataact aagttccctt cagttctatt tgaatcttgt tcttcaggtg gtggacgttt
    33901 tgatttagga cttatgtatt atgcaccgca agcgtggacg agtgatgata cggacccgat
    33961 agaaagattg aaaattcagc atggaacttc ttatggatat tctccatcaa tgatgacagc
    34021 ccatgtttct atttctccaa atgaacaaag tggaagacaa acgagtttgg acactaggac
    34081 aaatgtagct tattttagtt ctttcggtta tgaattagat gttacgagat tgtcggtaga
    34141 agaaaaagaa caagtgagag aacaaattca gttttataaa aaatatcgtt cattgcttca
    34201 atatggggat ttctatagga taaacagtcc ttttagttgt gattctgcta gttggcaagt
    34261 tgtttcaaaa gataaatgcc aatcgatttt attgtatgct caattgaata gtaagttgaa
    34321 tccaggttat acaagagttt attttagtgg tttagataaa gataaatgct attccgtctc
    34381 tggatttgat gagttctttt atggagatga attaatgaat gctggaataa aagtaagttt
    34441 aagtaattta gcactttgtg ttccagaata tcttacaaaa ttatttgtta ttgaagaagt
    34501 tgtatgtaaa tattgaggaa ataaaaatgg aaagtaaaaa aatagcaaaa cagattttaa
    34561 tagctacggc tgttttaaca agttttttag gaagtaattt ggtttatgca gatgtagttc
    34621 aaagtaattc taataacaga gctagtactg aaactgttag agtaacaggg aataacttag
    34681 aaaaacttat tactaaagat aaagaaattg ataaagagat gacatatctt tcagatatgg
    34741 attggtcttc tgcaactcat ggtgatatag ataaaacaaa aacagtacaa aaagatgctc
    34801 catttacaac aggaaataaa ggagagcata ctaagatttc attgctcact tctgatgata
    34861 aagttaaata ttttgataaa ggaataggaa cagtcgcaga ttctccatca gtaatcagct
    34921 atgatatcag cggtcaaggg tttgaaaaat ttgaaactta tataggaatt gatcaaagtg
    34981 ctaatagttc tagatcagac catgcagtag tggatagaat agaaatagaa attgatggaa
    35041 aggttgtcta ttctagtagt gtaactaatc cagaaggatt cagatataat acccaggcac
    35101 aatttattag tgtgacaatt ccacaaaacg ctaaaaaaat atccttaaaa tcattcgcag
    35161 gagaacatac atggggtgat gaggttgtat ttgctgatgc taaacttatt aaaactgtta
    35221 gtactcaaac tataactcca gatcttctta ataaaggaat taatggagga gtatatcttt
    35281 ctgatttaga atgggttgat gctactcatg gtgatgacga taaatcaaaa acagttcaga
    35341 aagataaacc gtttacacct ggtaataacg ggtctaataa taaaataaaa ttactaattg
    35401 acggtaagga agtcgaattt aataagggat tgggaactgt agcaagtaac ccgtctagta
    35461 taaaatatga tgtttcgggt gctaatgtta caagatttat ttcctatgtc ggaattgata
    35521 ggagtgcaaa tcatttaaat tcagattacg cagatattca aaaatttgaa gttgttgcgg
    35581 atggtaaagt catttactca tcagattcaa aatatccaaa aggaattaag tatgatacat
    35641 cggcatttct ggttgatgtt gaaattccca aagatacaca gacaatagaa cttaaatcat
    35701 attcagggaa acatacatgg gctgacgaat tggttttagg tggagccttg tttatggcaa
    35761 atggtaaatt taagaatcct aatgattggt cagaagttga taaacgtcgt gaaattaata
    35821 atgaacatcc gttacttatg atgcctttat atgctaacgg agaagagttt aaccaaggga
    35881 aatatacttt ttggggagga gatacattaa caggtaagtg ggagaatata ccagatgact
    35941 taaaaccata tactgttata cagttacatc cagatgatct tcctaaaaga gatggagctg
    36001 ctagagattt ttatgaacat atgttagaag aagcagcgaa atatgtaaat cctaagactg
    36061 gaaaaaatga accaattcca gttattctga cggtttacac tgctggtaat atgccttatt
    36121 atacttcggc acattggtta agtaccagct ggattgataa aatgtatcaa aaatatccaa
    36181 atttgcatgg tattttcagt acagagaatt attggatttg ggcaaatgat attgaaaata
    36241 aggcggcaga ttacttaaaa gtatcagcta aaaatggagg atattttata tgggctgaac
    36301 aaaataatgg ttctgcaata gaaaaagcat ttggaaaaaa cggtaagata gcatttcaga
    36361 aatctgttga taagtactgg aagaacctta ttttcatgtt caaaaataca cctgctgctg
    36421 agggaaatga ttcaactaca gaaagttata tgaagggact ttggctttca aatcatactt
    36481 atcaatgggg tggtttgatg gatacttgga agtggtatga gacaggtaaa tggaaactgt
    36541 ttgcaagtgg taatatcgga aaaagtcaag gagatagaca atggttgact gaaccagagt
    36601 ctatgctagg agaagaagct ttaggggttt accttaatgg aggtgtagtt tataattttg
    36661 aacacccagc ttatacctat ggtgtaaata ataaagaaag cttactcttt agcgaagtaa
    36721 taaaagaatt ttttagatat gtaatagcgc atccagcacc atccaaagaa aaggtacttg
    36781 aggatacaaa agtattcata catggagact attcaaataa aggaaatggt aagttctttg
    36841 taaacgtaaa tactgataga gaacaaactc cattatacat gactggtcgt tataatgtta
    36901 ttccagctat tccaggtgtt ttaaaaacag ataaattgaa agagtctgtt tctggtagcc
    36961 gtattcagat taaggaaatc acttctccag aatttagctc tactcaggct agaaaagaat
    37021 acttaaataa gctgtatcct atgaattatg aaggagatat ctttgctcag aaattagata
    37081 atagatggtt tgtctataat tacaaggtaa atgagaatgt taaacagact gggaaattaa
    37141 aatttaattc tttagaaatg gatgttgaat ttgaacctca tacctatggt atttttgaga
    37201 gaataagtaa tggattgaaa gtgaatttaa ataattttag aacaaataaa gattcactat
    37261 ggtctaatgc tcaagatgca aatcaggcaa agaaactacc acaattgacc aagaaaggtg
    37321 cgattaagtg gattgaagaa cattatatca aagatactca gtttggagag aaaagggtta
    37381 caaagatagt attaagaggt atagataaac ttcctactat tcattcatta tcaggaacaa
    37441 ataattccta tgatcagcca tctctcaatt ttgatcagaa aaatcatatg gttactatta
    37501 ccattaacag taacggaaat cttgaattcg aacttcattt ttagaaagga gtgagtttat
    37561 gtctcaagat gaaaaattaa ttcgtgaaca gatttgtgat gtttgtcata agatgtggca
    37621 acttggttgg gttgctgcta acgatgggaa tgtatctgtt cgattagatg aggataccat
    37681 tcttgcaaca cctactggta tcagcaaaag ttttattaca ccagaaaagc tggtgaagtt
    37741 aaatcttaaa ggagagattt tagaagcaga aggtgattac tgtccttcta gtgaaattaa
    37801 aatgcacatt cggtgctacg aagaacgtga ggatgttcgt tcagttgttc acgcgcatcc
    37861 accgattgca acaggatttg ctcttgcaca cattccttta gatacttatt cactaattga
    37921 gagcgcgatt gtggtagggg caattcctat aacgccattt ggagttccgt ctacaatgga
    37981 agtgccagaa gcaattacac cttatctgcc cgatcatgat gtcatgctat tagaaaatca
    38041 tggagctctg actgtcggaa gcgatgtcat tacagcatac taccgtatgg aaactttaga
    38101 attagtcgca aagacaacct tccacggaag aatgttactt tctacaaagg gcattgagga
    38161 gcaagaaatt gctcgtccga ctttagaacg tctattctca atgcgagaaa attataaggt
    38221 tacaggtcgt cacccaggct accgtaaata taatggcgat ggtagtatga aagaaacaga
    38281 aaaataagag gaaaatagta tgattcaaca tccacgtatt ggtattcgtc cgactattga
    38341 tggtcgtcgt caaggtgtac gcgaatcact tgaagtacaa acaatgaaca tggctaaaag
    38401 tgtggcagat ttgatttcaa gcacattgaa atatccagat ggggaacctg tggaatgcgt
    38461 gatttctcca tctactattg gccgtgtacc agaggctgca gcttcccatg agttgtttaa
    38521 aaaatcaaat gtttgcgcaa caattacagt tacaccatgc tggtgttatg gtagtgaaac
    38581 tatggatatg tctccagata ttcctcatgc tatttgggga tttaatggga cagaacgccc
    38641 aggagctgtc tatcttgcag ctgtactagc ttcacatgct caaaaaggga ttccagcctt
    38701 tgggatttat ggaagagatg ttcaggaagc tagtgacaca gatattccag aagatgtcaa
    38761 agaaaaactt ttacgctatg cgcgtgcagc tcttgcaact ggcttgatga gagacactgc
    38821 ttacctatca atgggtagtg tttcgatggg gattggtggt tctattgtaa atccggattt
    38881 cttccaagaa tacctaggaa tgcgaaatga atcggtagat atgacggagt tcacgcgccg
    38941 tatggaccgt agtatttacg accctgaaga gttcgaacgt gcgctcaaat gggtgaaaga
    39001 aaacgtaaaa gaaggattcg accataaccg tgaagacctt gttttaagcc gtgaagaaaa
    39061 agatagacaa tgggaatttg ttattaagat gttcatgatt ggacgtgact taatggttgg
    39121 taacccaaga cttgctgaac ttggttttga ggaagaagca gttggtcacc atgctttagt
    39181 agctggtttc caaggtcaac gtcagtggac agaccatttt ccaaatggag attttatgga
    39241 aactttcctc aatactcagt ttgactggaa tggtattcga aaaccatttg tatttgcgac
    39301 agagaatgat tcactaaatg gtgtgtctat gctctttaat tatctattaa caaatactcc
    39361 acaaatcttt gctgatgtgc gtacttattg gagcccagag gctgttaaac gtgtaacggg
    39421 acatacttta gagggtcgtg ctgcagctgg cttcttacat ctaatcaact ctggttcttg
    39481 tacattggat ggtacaggtc aagctactcg agatggcaaa cctgttatga aaccattctg
    39541 ggagttggaa gaaagtgaag tgcaggctat gcttgaaaat acagacttcc caccagcaaa
    39601 ccgcgaatac ttccgtggag gaggattctc aactcgtttc ttgacgaagg gggatatgcc
    39661 agtaacaatg gtacgtctca atcttctaaa aggggttggt ccagtgctac aaattgcaga
    39721 aggttataca cttgaacttc ctgaagatgt tcaccatact ttagataatc gtacagatcc
    39781 aggatggcca actacttggt ttgctccacg tttgacagga aaaggtgctt tcaagtctgt
    39841 ctatgacgtc atgaataatt ggggagctaa tcacggagcc ataacatatg gacacattgg
    39901 agcagacttg attaccttgg cttctatgtt gagaattcct gtcaatatgc ataatgtacc
    39961 tgaggaagat atctttagac ctaaaaattg gtccttattt ggaacagaag atctagaatc
    40021 agcagactat tgtgcatgtc agttgttggg accactacat aaataaaact tgtttatata
    40081 ggaggtgaac ttacgtccct cctatccttt taaaaagatt tgttaaacaa ttcacaaata
    40141 attaaaaacg aatacaaaaa gtaatataat gatgttaaat agatagcgcg gaggcgcagg
    40201 aggaaaatta tatggctaca ttttatgttc cggcagtcaa ccttattgga aaaggtgttg
    40261 taaatgaagt gggtccttat atcaaggaac ttggctataa aaaggcactt ttggttacag
    40321 ataagtacat cgaaggcagt gatattttac ctaagacttt aaaaccactg gatacagaag
    40381 gaatcgaata tgtcatcttt agcgatgtag agccaaaccc tacttgtaaa aatgtcacag
    40441 atggggtagc tgctttgcaa gaacatggct gtgactttat catcagtctt ggcgggggtt
    40501 ctccacagga tgcagctagt tgtatttcta tcatggctac aaatggtgga aaaccacagg
    40561 attatgaagg gcttcataag tctgctaaaa aaggcttgcc agttgtggct atcaatacaa
    40621 cggcaggaac ttctgcagaa atcactatta actatgtgat tactgatgaa gaacgcaagg
    40681 ttaagatggt aatggttgac aagaatagcc ttgctcttat ctctgttaat gacccggaac
    40741 tcatgctttc caaacctaaa ggcctgactg ctgctactgg tatggatgct ctgactcacg
    40801 ctgttgaagc tttggtaaca cctggtgctt atgatgtaac caagaaactg tctattggtg
    40861 ctattgagct tatcaaggaa tatcttcctc gtgctgtaga aaatggacat gatattgaag
    40921 cgcgtgaagg tatggtcaat gccatcttcc ttggtggtat gagctttaat aatgctggtc
    40981 ttggttatgt tcactcaatg gctcaccaac tcggtgcagt atataatttg ccacatggcg
    41041 tgtgctgtgc catgttgcta ccagttatag aacgtgaaaa tgctaaacgt gtaccagaag
    41101 ctttccgcaa tgttgccaaa gccttgggac ttcatgtaga aggtaaatca gatcaagaat
    41161 gtgccgatta tgcgattgct gagattgaga agctttctga gacagtaggt attcctaaga
    41221 aactgactga acttggtatt gaagaaaaag atttcgactt tgaatacctt tctaagaatg
    41281 ccttgattga tgcctgcgca ccaggaaatc catttatgcc aaccttagaa gaaacgattg
    41341 ccttttataa agagttattt tagcaagaga ttggacgaca ataggacaat tcacctctaa
    41401 ttattgacat ttcaggaaaa atcgcagtaa aaacggcaca gccttcttta aatgtgctat
    41461 aatactagaa aaatacttgt ggaggttcca ttatggcaat atttttcatg atttttctga
    41521 ttgtttgtgt gctcctattg gtgatagtca cactgagtac agtttatgtg gttcgtcagc
    41581 agtcggtggc gattattgaa cgctttggga aataccaaaa ggttgctaat agcggtattc
    41641 atattcgctt gccttttggg attgactcga ttgcagcacg gattcagttg cgcttgttgc
    41701 aaagtgatat tgtggttgag actaagacca aggacaatgt gttcgttatg atgaatgtag
    41761 cgactcagta ccgtgtcaac gagcagagcg tgacagatgc ttactataaa ctcatacgtc
    41821 cagaatctca gattaaatct tatatcgaag atgctcttcg ctcttctgtt ccaaaattaa
    41881 ccttggatga attgtttgag aaaaaagatg agattgccct tgaagttcaa caccaagtag
    41941 cagaagaaat gaccacttac ggctacatta tcgtgaaaac cttgattacc aaggtcgaac
    42001 cagatgcaga agttaagcaa tctatgaatg aaatcaatgc ggcgcaacgt aagcgggtcg
    42061 cagcacaaga attggcggaa gctgacaaga ttaaaattgt cactgcagct gaagccgaag
    42121 cagaaaaaga ccgccttcat ggtgtgggga ttgcccaaca acgtaaggcg attgtggatg
    42181 gattggcaga gtctatcacc gaactcaagg aagccaatgt tggcatgaca gaagaacaaa
    42241 tcatgtctat cctcttgacc aaccagtatt tggatacctt gaataccttt gcctctaaag
    42301 gaaatcaaac catcttttta ccaaatactc caaatggtgt ggatgatatc cgtacacaaa
    42361 tcttgtcagc ccttcgcgct gagaagaaat aatagactaa tactcttcga aaatctcttc
    42421 aaactacgtc agcgtcgtct tgccgtatag atgttactga cttcgtcagt tctatctgca
    42481 acctcaaaac agtgttttga gctgacttcg tcagtcttat ctactacctc aaaacggtgt
    42541 tttgagcaac ctgtagctag tttcctagtt tgctctttga ttttcattga gtataaagag
    42601 cttggcaaca ggctcttttt gtattgcgtt tattaagaaa aacaaaaaac atcgatatac
    42661 atttaactaa aaattattgt atgttatctc ccttaattag gaatgataag ggaataacta
    42721 gaaagatttg tgaatacaaa ctatttctga tatacaaaat atacagtaat aatgaatgat
    42781 gggagatggg atgaaagaat ttcaatttga gagaaagcag cgtttttctt tgaggaaata
    42841 tgcaatagga gcttgttcgg tcttgctagg aacgagttta ttttttgctg gtatgggtgc
    42901 tcagcctgta caggatacag aaacgagttc agcactaatt tcaagtcatt atttggatga
    42961 gcaggattta tctgaaaagc tgaaatctga gttgcaatgg tttgaattag aaaacaagct
    43021 tttgaactta tgggagcatt aggttactat gaaggatttg ttccttatgt ttcaaatcaa
    43081 taccaaaacc aagctgaaga agaatacaaa ccgctatctg ataaatatat tttcgaaaaa
    43141 atcttaggaa aaacatatgc agccttcaaa aaagatcaaa ttaatgagcg tgtcgagaaa
    43201 ttaggtaagt taaaacctat tacaataaat tacaacggaa aatcagaagt aattgatagt
    43261 aaagaaaaat tacaagagct tatgaataaa gccgttaaag acgaagtggc tcaaatatag
    43321 taaaatgaaa taagaacagg acaaatcgat caggacagtc aaatcgattt ctaaaaatgt
    43381 tttagaagta gaggtgtact attctagttt caatatacta taaaatcagg caataccacg
    43441 gctaaaaagt ttgagtttat cgaaatacca gtgcaaaaac tgaaaaaagc aatttataaa
    43501 gctcatctca aagattcaga tgactttaga ccagaaacat ccacaccaaa tctttttgaa
    43561 agctgtttga agctttgtcc ttgctttctt agttcataga tctgaacttt atcttcataa
    43621 ctcaatttca taataaaaca ccccaaaagt tagatttatt ctgtctaact tttggggtgc
    43681 agttcattaa tcggtcgatt ttttttgtag aaacagttgc ctgattaagt tgcaagtcga
    43741 tagacggctt cggcataaat atccatagca cggtacaaat cttctagaac ggcacattca
    43801 tttgcctgat gttctgtctg cttcgctcct gggaataagg cgccgaaggc tacacaattt
    43861 ggcatggtgc gagcaaaagt ggcaccaccg gatgaaatag caggactgtt atcgccagtc
    43921 ttttcttggt agatttgcat cagtgtgcta acgagtttac tgtcttttgc gacgtataga
    43981 ggcgctagat agtcaaactc ttcgtagcgg agttggtagt tttgtgcaca tcttgtaagc
    44041 aactctacta gttcttcctt gtcagctaag acaggagtcc gaatgtcaat acggatttca
    44101 gaacgttcat gattgatcat gagacctgcg acattaaagg ataggtgacc agaaggttca
    44161 tctgctatat caccaaagat ttgtcttcct gtgccgtctt gacctgcttg tgttgcaaga
    44221 aaactgagag cagggtgttc ttggagagga gcaagaatgg tagctagtcg gatgacagca
    44281 ttgatacctt gactagcatc cttagcatgc tttggcactc cgagaaccgt tacggtttgt
    44341 tcagtggttt ggtaatcata accagcttct ttgagaccgt tacaaacctg ttcatagagg
    44401 agaccttggt agttggcctt gtctggtaca acgttaaagg cgcctcctac ttcaagctct
    44461 agttgatccg atcccgggcc atgaagtttg acctgtagaa gccctttttc agcataggtc
    44521 agaggaaaag atgagtcagg tgcaaagccc atactggcct gttcttcgat ggtattgtag
    44581 cgtgccatgc agcgccagag ggtttcctca tcggtaccaa agataaagcg tacgcgcttt
    44641 ttgaactgaa taccttggtc cagcaagctt tttactgcat agagagctgc gagcgaaggg
    44701 cctttatcat cttggacacc acgtccgaat acccagccgt ctttgatagt tgcttcaaat
    44761 ggcggtgtct gccaatctgc ttcatcacct gatggaacaa catccaaatg acagagaatg
    44821 gccagaagct ctgctccctg accgatttct gcatatccgt aataaccttt agggtcaaga
    44881 taggtagtga aacctatgtc tcgacaaatc tctaaagttt tttctaggac atcttggatt
    44941 gcttgtccaa aaggtgttcc attttctcct tcattgagta ctgaaggata ggaaatcaag
    45001 gtttttaatg atataagaaa ttcatcttta acttgatttg ttatatctat tttcatggaa
    45061 tcacctcact cactatttta taggaatgga aggaaggttc caaggagaag aagggcgatg
    45121 gtcactacaa taatagcgac tacgagtttg cccatgaatt tccaccaagt accaatgttg
    45181 atacgtccaa gtgcaagagc tcccatcaca ataccagatg ttggtgcaat caagttcaag
    45241 acacctgaag cagattggta agcagtgata atcaagctag gacggacatt tacaaattct
    45301 ccaagtggag ccatgatacc catagttgcg ctggcaagac cagatgaaga tgggatcaag
    45361 aatgacatag gtagatagaa gatataagtt acaacgataa agacttgtga agatagaccg
    45421 ctcaagcctt ctttacccca gttgaggatt gtatcggtaa tcataccgtc gttcatgata
    45481 acttgaatac cacgagcaat cgctacgatc aaggcaacac tgagcaagtc agcagcacca
    45541 ttcatgaagg aagagataat cttatcttct ttaagaccat aaataacacc aatcaggata
    45601 cccataaagg caaagagcat ggcgccttct gggaagtacc aagtacctag tgcagaagta
    45661 gatgaaccga caatattacc aataactgga agaccagtca accaagcatt aaagtcatca
    45721 aaaatggtaa cgccaaggtc tgtccatgga atgaagctca ataccatcaa gatgaatgtc
    45781 aacacaaata agaagagaac tgatttttgt ttgctgctaa gtgtagattc tacagatgaa
    45841 gattcttcta cgttaaagtg tttcaaatct tctttgcgag tactataaac cagtgactta
    45901 gtcggatctt tttgaatctt atccgcataa cggtaaacaa accaagtact aagagcagtc
    45961 aaggtaaccc agaaaatcag acgaagtacg ataccgtccc ctgtaccaac tcccgcagtc
    46021 gctgaagcaa tacctgtcgc aaatggattc agagtagatg ccaaacagcc gatttgagaa
    46081 ccgagcaaaa taattgcaac accagtcagg ctatcaaaac caacggccat cataactggc
    46141 acaaggagtg gatagaaggc cattgtttct tcccccatac cataagttgt accaccgagg
    46201 gcaaacaaag gcatcagtac caaaattaac attttttcgc ggcccttata cttcttcacg
    46261 atagaggcaa tccctacgtc aagagcacca gttttgttga caatgccaag gaaactacca
    46321 accataagga tgaagaaggc tacatcaatc gctgcgctcg tttctttaat gagcgaacct
    46381 tcctctggat gagtacctag catagcccga atcggtgcca tgaggacatc ccaaatccct
    46441 tgtggatttt gaggctgagt ctcgtaaata ccttctataa aggcccccgc agggataaac
    46501 caagttagta ctgccataat agcaatgatt atcaataata cggtgtaaga tgaaggcatc
    46561 ttaaaccctt ttttagcttt ttcactcatt tgtttttcct cctgatgtct aacaaagtgt
    46621 aaaaaaccaa ctactttctt aaataaacat ttaagaaaac gctttctatt tatatttgtt
    46681 ttaccatatt aaagtctaaa aaactaatat cttttgaaat attgtacatg ttttcaagaa
    46741 taatttctaa tttgatataa agatactaga aatagaatac atcttattag taaaacaact
    46801 tatccttttt caataattgt tccactttca gattcaatca aggcgcctag attttcaagg
    46861 gaagtaataa ctgcttttcc ttctggacga ccattgacaa aagcgatagc tgcttctact
    46921 tttggaagca tgctacctgg tgcaaactga tcttgtttga tatattcttc cagctgggca
    46981 acattcacat gttccaattt ttcctggttt ggcttgttgt agttaacaaa tacataatct
    47041 acacctgtca aaacgatgaa gaggtctgca tcaaccaatt ctgccaaacg ttgggaagcg
    47101 aagtctttat caataaccgc ttcgacacca gtcaaatgtc cattgttttc tttgacgacg
    47161 ggaataccgc caccacctgc agctacgacg acttgaccac tatttaaaag agtacggatg
    47221 gtttcaattt ctttgatgtc aacaggtttt ggtgaggcaa cgaccttacg ccagccacgg
    47281 ccagcatctt ccttgaaagt cgctccgctc ttttcggctt ctgcttttgc ttcttcttct
    47341 gaatagaaag gaccgattgg tttactcaag ttaacaaaag ctggatcatt tttatctacg
    47401 ataacttgcg ttacaacaga ggcaacattt ttttcgatgc cttcatccaa gagagcattt
    47461 tgcaaagcat ttttcaacca gaaaccgatg ctaccttctg tcatagcgac aagtgagtcg
    47521 agtgggaagg cagggttctt ttcagagtct gatgccaaat gttggagcaa gagattccca
    47581 acttgaggtc cattaccgtg agtgataatc aaatcatctc catttttaat caattttaca
    47641 agatgcttag ctgtttcaac taaagcttct tgttgagcct ttgctgatgg gtcagaagaa
    47701 agaatcgcat ttcctcccaa agctactaca attttacgat ttgccataaa ttctccttta
    47761 tcacactcaa tagaatgcgt ttagatttca atttaatgat ttttcacata ttttataaga
    47821 aataatagat taccattata taaaagagga ccggactaaa gctattagtc gcagccctca
    47881 tagctgttgg tagacggttt attatctaaa attatacttt aggaatataa aggttaccaa
    47941 gtgtcgcagc cataacagct ttgatagtgt gcatacggtt ttctgcttga tcgaagtggc
    48001 gagcgtactt gctgcggaag acttcgtctg ttacttccat ttcttctaca ccaaattttt
    48061 cagcaacgtc tttaccataa acagtgtgag tatcgtggaa tgctggcaag cagtgtagga
    48121 agatcaagtt ttcattgcct gcttttttaa ctaagtccat attgacttgg taaggtttaa
    48181 gaagagctac acgttctgcg aatttgtctt cttcacccat tgatacccaa acgtctgtgt
    48241 aaagaacgtc tgcatcttta actgcttcat cagcatcttc agtgatgaga acatgtgcgc
    48301 cactttcttt agcaaatcct tctgccaatt caacgatttc tttgtctggg aagagttctt
    48361 ttggtgagaa gatgtgaaca ttgacaccaa ggatagcacc tgttacgagc aagctgttgg
    48421 caacgttgtt acgtccatca ccacagtata ccaatgtcaa gccttccaag cgaccgaagt
    48481 tttcttgaac agtcaagtag tcagcgagca tttgagttgg gtgccattcg tcagttagac
    48541 cgttccatac tggaacgcct gagaattctg ccaattcttc aaccatacgt tggctgaatc
    48601 cgcggaattc aatcccgtca aacatacgtc ccaatacttt agcagtatct tcagtagatt
    48661 cttttttacc caactgaata tcatttgctc cgaggtattc tgggtgagca ccaaggtcga
    48721 tagccgcagt tgtaaaggct gcacgagtac gagtagatgt tttttcaaat aggagagcga
    48781 tattcttgcc agcaaggtag tggtgttgaa tattgcgttt tttcaaatct ttcaagtgag
    48841 ctgaaagacc aataaggtat tctaactctg cacgggtaaa gtctttttct gctaagaagc
    48901 tgcgtccttg gaatactgaa tttgtcattt tattatttcc tctttctatt ttttacattt
    48961 tctattgacg aataccgaac agcgattaca cttcttcacg ttcaaatggc atagacatac
    49021 aacgaggtcc accacggccc cgaaccaatt cacttccgcg aatcttaatc aagcgaagcc
    49081 cgtattcttc caaaatctta ttggtcacgg tattgcggtc ataaacaact accacaccag
    49141 gtgcgatggt caaagtgtta gaaccgtcgt tccattgttc acgcgcagct gctacgatat
    49201 tgccaccacc gcaacgaatc aaatgaactt tttctacacc aaggttttga gcaagaagtt
    49261 cagctaagtc acctttctct tcaacgattt taagtttttc gttttcgtaa gtaactgagt
    49321 aaacgtgaag gtcgccttcg atttctgggt gaatagtgaa cttgtcatag tctaccatag
    49381 tgaagacagt atccaagtgc atgaatttac ggttgttagc aaattcaaag gccaaaactt
    49441 tcttgaagcc aacatttttc ttgaagatgt tgaccaaaag tttttcgata gaagctgcgt
    49501 ctgtacgttg agagatacct actgcaagga cgtctttaga aagaactaac tcgtctccac
    49561 cttcgatacg cgtatcttct tcacggttgt agaccaaatc cacttttccg ccatagattg
    49621 ggtggtattt gaagatatac ttaccgtaga gtgtttcacg gttacgagtg tctgcaaaca
    49681 tgtggttaag cgatacggcg tttccaattg ttgcaaatgg gtcgcgagtg aaatagaggt
    49741 ttggcatcgg gtcaattgca aatggataat ctgattcaac taagtcagtt agatctttag
    49801 cttcgtcagg aatttctggc aattcaactt tttgaatccc agccattgtt ttttcaacca
    49861 attcttggtt gtccttgatg ccgtgaagca attcacgaat agcaaccttg gtttgacgat
    49921 cacggatgtt ggcttcgtct aagtattcct cgataaattg atcgcggatt tctggagagg
    49981 tcaatgattc agcagcgagt tgttctaggt agagaacctc aattccttca tcgcgaagag
    50041 cttgggcaaa tgcatcatgt tctttttgag catcttccaa gaaaggaata tcatcaaaaa
    50101 gaagcctttc aagatagtcc ggcaacaagt tttctaactc cttgcctgga cggtgcaaca
    50161 taactttttt cagtttccca atttctgaga agacctgaat tggatgagaa gacatgtatt
    50221 ttcctcctta aaaattttga cttggcacca ttttgggtac cgcttacatg tatgttataa
    50281 cgcaattcct aggtaatgtc aatggctata atttctcgga aaataatata aattatgatg
    50341 tttagcacaa ttttatgtta ttatacataa cataggatag aatacataga tacaaatgca
    50401 taaacttcta taaaaaggat ataaaatttt tttaaaaaat ttttcaaaaa atatacaaat
    50461 gaccaaaaag tgtccaatta tcatctggtt atcacttgga tctgtataaa gagaaatgtt
    50521 tgtgtgaaag gataaaaaga tgcaacattc ttttgaagat agattttgga gaagcatttc
    50581 ttgttcaatt gtacaaatta tagaatcttt tctgagtatt taggaagaga taattatctt
    50641 attgaccctc tttttatttt ttgttatagt cgacgaggtg atagcttaga ataatcactt
    50701 attcacaatc tgtggaaaag tctggagagt gaatggtctt cacacaatga cctgaaagaa
    50761 gcctgagaat aattatggag agtagcattc tgagaggtgt tagcagaacc atatgacaga
    50821 gctgtttgaa gagggaacat tgaggagaaa aatcctgagc ctaccagttg gagttggaaa
    50881 gagctggctg ttagatcatg gtttattatc cacaacctgt ggataacctt gtgaacaaga
    50941 gaagttgcaa aagaaggaga tatataacga tgaagaaaat caaaccgcat ggaccgttac
    51001 caagtcagac tcagctagct tatctgggag atgaactagc agcttttatc cacttcggtc
    51061 ctaatacctt ttatgaccaa gaatggggga ctggacagga ggatcctgag cgctttaacc
    51121 cgagtcagtt ggatgcgcgt gagtgggttc gtgtgctcaa ggaaacgggc ttcaaaaagt
    51181 tgattttggt ggtcaagcac cacgatggct ttgtccttta tccgacagct cacacagatt
    51241 attcggttaa ggtcagtcct tggaggagag gaaagggcga cttgctcctt gaagtatccc
    51301 aagctgccac agagtttgat atggatatgg gggtctacct gtcaccgtgg gatgcccata
    51361 gtcccctcta tcatgtggac cgagaagcgg actacaatgc ctattatctg gctcagttga
    51421 aggaaatctt atcaaatcct aactatggga atgctggtaa gttcgctgag gtttggatgg
    51481 atggtgccag aggagagggc gcgcaaaagg ttaattatga atttgaaaaa tggtttgaaa
    51541 ccattcgtga cctgcagggc gattgcttga ttttttcaac agaaggcacc agtatccgct
    51601 ggattggcaa tgaacgaggg tatgcaggtg atccactgtg gcaaaaggtg aatcttgata
    51661 aactaggaac agaagcagag ctgaactatc ttcagcacgg ggatccctcg ggcacgattt
    51721 tttcaatcgg agaggcagat gtttccatcc gtccaggctg gttctaccat gaggatcagg
    51781 atcctaagtc tctcgaggag ttggtcgaaa tctactttca ctcagtaggg cgaggaactc
    51841 tactcttgct taatattccg ccgaatcaag ctgggctctt tgatgcaaag gatattgaac
    51901 gactttatga atttgcgacc tatcgcaatg agctctataa agaagatttg gctctgggag
    51961 ctgaggtatc tggtccagct ctttccgcag actttgcttg tcgccatttg acagacggcc
    52021 ttgagaccag ctcttgggca agcgatgcag acttgcccat ccagttagac ctcgatttag
    52081 gttctcctaa aacttttgat gtaattgagt taagagaaga tttgaagcta gggcaacgaa
    52141 tcgctgcttt tcatgtgcaa gtagaggtgg atggtgtctg gcaggagttt ggcaggggct
    52201 tcacagttgg tcataagcgc ctcttgcgag gtccgctagt agaggcacaa aaggtgcgcg
    52261 tgatgattac cgaggcacaa tctatccctg tattgaccaa gatttccctt tataaaactc
    52321 ctgggttatc aaaaaaagaa gttgttcagg aactagcatt tgcagaaaaa agcctagctg
    52381 tggcaaaggg agagactctt cattttagga ttgaacgtag tgaaagtagc tcctctttag
    52441 aggctaagat ttcgattcaa ccggggacag gtgtccatgg tgtcgcctat caggatgaga
    52501 ttcaagtcct tgcgtttcaa gctggtgaga ctgaaaaaag gctgacgcta ccaaccttgt
    52561 atttcgcagg agataaaacc ttggatttct atctgaacct aacggtggat ggtcagcttg
    52621 tggatcaact tcaagtccaa gtttcataaa agaagaacct ttgcgagatg caaaggttct
    52681 tttggttatt agtgacttgg taaccagctg agggtgaaag ttagttgttc agcttttaag
    52741 aggtcttggt gttgaatagt tgatacgagt gttttgtcca gtcggcattc tttgacaaag
    52801 ttaaaatggt tgtggttttg tttagtatgg atatccagcc atttatcttc tttagcgagg
    52861 tagactcgta gatggtcaaa gagagggatt ccgaggtcat agcttggttt tcctggacag
    52921 gttggataaa atccgagagc tgaccagatg taccaagcag agagactacc attgtcttca
    52981 tctccaggat aggcttccca acttgggtga aaagctttct gacggagcgt cttgataaga
    53041 agggcagtgt agtcagggta atcgctgtag cggaagagat aaggaatgtg gaaactaggc
    53101 tggttggaaa tggctatctg tccaaaagga gcagtagcca tctcgctcat ttcgtgaatt
    53161 tcgtaaccat agcctgttgt ttcaaagagg ggagcatctt gacaggcttt caaaagatag
    53221 ttgctaaagg tttcttttcc acccatcagt tggattaagc cagggatgtc gtggagaacg
    53281 cctaaagtag cttgaatggc agagcattca gcgtagtctc gcccccaact ataaggagag
    53341 aagtcagggt gaaagtttcc ttgattgtct cgtgctcgca tgtaacctgt ctcagcgtca
    53401 aatagctggc ggtaattttg tgaagcagcc ttgtaggttt cagcgatttc tatgttctct
    53461 agttttttgg cacagctggc gatacaaaag tcactatagg catagtctag agtatggcta
    53521 acactttcat ggtggtcggt agagaggtaa cctagttctt ggtattgggc tagtccgtgg
    53581 cggccattga tgccgagagg gtcggctttg ctggctgttt cgagcatggc ttggaagagt
    53641 tctccttcta ggtcaggggc catgtccttg caggcgctat ctgcgataat accgtctaaa
    53701 agtgtacctg gcatcatacc ccgttcatct ggagccagcc attttggaag gaaaccagta
    53761 tcgcggtagc tattgaggaa accttctaaa aagcgttgat agtgctccgg tatgataagg
    53821 gcaaagaggg ggaaggtggt gcggaaggta tcccagaaac cattgttgct aaagaggaca
    53881 ccaggcttga cagtaccagt agccatatcc atgtggatgg cttgccctga ctcatcaacc
    53941 tcataaaaag tctgtgggaa gaggaagagt ctgtagaggc agtggtcaaa gaaggttcgg
    54001 tcagcctctc ctgtctctat aatgtcaaaa cgatggagga gattttccca atccgcttgg
    54061 gcacttgctt tacagctatc aaaatcttct tgaggtagat tgattagagc ttgagaagga
    54121 gagatgaaag aagtggctag ttgcatctcg gtttgactac ttgctaagtc aattcgccag
    54181 tccccagctt cttggctgat agcaagaata tccgtgttca tttgcagggc agtaaacatc
    54241 gttagcgaat ttttgttggt ttcagtttta ccttcttgtc gcagggcaag agttcgctta
    54301 tctacttgct ctactgtcag ttcatctgtt gcgtgaagat agagggagag ggctttgcct
    54361 tgcttttgct tcaaacgaat agaagcaccg tagcaagtcg gtgtgagctg ggtttcaatc
    54421 tgataacgca gagaaaagag cttcaaatag tgaggctgga agcaagcttt atctatatca
    54481 taagaagact ggcggtgaaa gaggctgtct ccacccagtt gactggtgac aggtgtcaga
    54541 aggagccaag agtagtcccc aatccaagga ctgggctggt gagttaatcg aatcccctga
    54601 aagataggca gatgcggatc aaaaaaccaa gatccatcct ggtcactggt ctggggcaca
    54661 aagtaattca tcccaaaagg cacgcctgtg tatggcaggg tatttccccg agaaaaggca
    54721 tgcttgttgg tagttccaaa gcgggtatcg atggtttcaa gtagtggttt catagtcttt
    54781 cctttagctg tttttctaca ttatatcaga aaaagagggc ctttagaaaa ggagtttcaa
    54841 aaataactat tttgtagaaa aatgactatc atttgtgtat gtattttctg tctcaaaagc
    54901 tatatactga acatgaaact tgtttgaaag agggaattgc acgatgattt attcgaaaga
    54961 aattgttaga gaatggctag atgaagtagc agagcgggct aaggaccatc cagagtgggt
    55021 ggatgttttc gagcgttgct acaccgatac cttggacaat acggttgaaa tcttagaaga
    55081 tggttcaact tttgtcttga ctggggatat tcctgccatg tggcttcgag attcgacagc
    55141 ccaactcaga ccctaccttc atgtagctaa aagagatgcc ctcctgcgtc agaccattgc
    55201 aggtttggtc aaacgtcaga tgaccttggt actcaaggat ccctatgcta actccttcaa
    55261 cattgagaag aactggaaag ggcaccacga gactgaccac acagacctta acggctggat
    55321 ctgggagcgc aagtatgagg tggattcact ttgctatcct ttgcagttgt cttatctcct
    55381 ctggaaagaa actggcgaga ctagtcagtt tgatgagact tttgtcgcag cgactaagga
    55441 aattcttcat ctgtggacgg tagaacaaga tcataagaac tctccttatc gttttgtccg
    55501 agatacggac cgcaaggaag acaccttggt aaatgatggc tttggacctg attttgcagt
    55561 gacaggaatg acttggtcag cctttcgtcc gagcgatgac tgctgtcagt atagttactt
    55621 gattccgtca aatatgtttg ctgtagtagt cttgggttat gtgcaagaaa tcttcgcagc
    55681 attaaaccta gctgatagcc agagtgttat tgctgatgcc aagcgtcttc aggatgaaat
    55741 ccaagaagga atcgaaaact acgcttacac caccaacagc aagggcgaaa agatttacgc
    55801 ttttgaagta gatggcctag gaaatgccag catcatggat gatccgaatg tgccaagtct
    55861 actagctgcg ccctatctgg gctactgttc gatcgatgat gaagtgtatc aagccactcg
    55921 ccgtaccatt ctgagctctg aaaattcata cttctaccaa ggagaatacg ctagcggtct
    55981 tggaagttct cataccttct atcgctatat ctggccaatc gccctttcta tccaaggatt
    56041 gacaacaaga gataaggcag agaaaaaatt cttgctggat cagctggttg cctgcgatgg
    56101 tggtacaggt gtcatgcacg aaagcttcca cgtagatgat ccgaccctct actctcgtga
    56161 atggttctcc tgggctaaca tgatgttctg tgagttggtc ttggattact tggatattcg
    56221 ctaaggggct cgctttagct caaccgattc ttatcagaat cacaagttta catttaaaac
    56281 gttaaaattt aaatttagaa tgaggtttta cttcatggaa aatgttgttg tacatattat
    56341 ctcacatagt cactgggacc gtgagtggta cttgcctttt gaaagccatc gtatgcagtt
    56401 ggtggaattg tttgacaatc tctttgatct ctttgaaaat gaccctgagt tcaagagttt
    56461 ccacttggat ggacaaacta ttgtccttga tgactactta caaattcgcc ctgaaaatcg
    56521 tgacaaggtc caacgctaca ttgacgaggg caaacttaaa attggtccct tttacatctt
    56581 gcaggatgac tacttgatct ccagtgaagc caatgtccgc aataccttga ttggtcaaca
    56641 agaagctgcc aaatggggta aatcaaccca gattggctac tttccagata cctttggaaa
    56701 tatgggacaa gctcctcaaa tccttcaaaa atcaggtatt cacgtggcag cctttggtcg
    56761 tggtgtgaag ccgattggat ttgacaacca agtccttgaa gatgagcggt ttacatccca
    56821 gttttcagaa atgtactggc agggtgtgga tggtagtcgt gttttaggta ttctctttgc
    56881 caactggtac agtaatggga atgaaatccc agttgacaaa gatgaggcct tgaccttctg
    56941 gaaacaaaaa ttgtcagatg tgcgtgccta cgcttcgacc aaccaatggt tgatgatgaa
    57001 cggctgtgac caccagcctg tacagaaaaa tctgagcgaa gccattcgtg tggcaaatga
    57061 actcttcccg gatgtaatct ttgttcatag ttcttttgat gaatatgttc aagctgtaga
    57121 aggtgcgctt cctgaacact tatcaactgt tacaggcgag ttgaccagtc aggaaacaga
    57181 tggctggtac acacttgcca acacttcttc atcccgcatt tacctaaaac aagccttcca
    57241 agaaaatagc aacctcctag agcaagtggt agaacccttg actattatca ctggtggaca
    57301 caaccacaag gaccagttga cctatgcttg gaaaacactt ttgcagaatg cgccacatga
    57361 tagtatctgt ggctgtagcg tggacgaagt tcaccgcgag atggaaacgc gttttgccaa
    57421 ggtcaaccaa gtaggaaact ttgttaaaag taacttgctc aacgagtgga agggtaaaat
    57481 tgctacggat aaggctcaaa gtgactatct ctttactgtc attaacacag gcttgcatga
    57541 taaggtcgat actgtcagca cagtgattga tgtggcgact tgtgatttca aggaattgca
    57601 cccaacagaa ggctacaaaa agatggctgc tcttatctta ccaagttacc gtgtggagga
    57661 cttggatggt cgtcctgtag aggctacaat cgaagacctc ggagctaatt ttgagtacga
    57721 tttaccaaaa gacaagttcc gccaagctcg tattgctcga caagtgcgcg tgaccattcc
    57781 agttcaccta gcgccgcttt cttggacaac cttccaattg ctggaaggaa aacaagaaca
    57841 ccgtgagggt atttaccaaa acggagtgat tgatacacca ttcgtaacgg tgagtgtgga
    57901 tgacaatatc acagtatatg acaagacaac tcacgaagcc tatgaagact ttatccgctt
    57961 cgaagaccgg ggtgacatcg gaaacgagta tatctatttc caaccaaaag gaacagagcc
    58021 aatctttgca gagcttaagg gccacgaggt cttggaaaac acagcttgct atgctaaaat
    58081 cttgctcaaa catgaattga ccgtgcctgt cagggcggat gaaaagctag aagaagagca
    58141 acaaggtatc atcgagttta tgaagcgtga ggctggacgg tcagaagaat tgacaaacat
    58201 tcctctggaa actgagttga ttgtctttgt tgacaatcca caaatccgct tcaagactcg
    58261 ctttactaac actgccaagg atcaccgtat ccgtctcttg gtcaagactc ataacacgcg
    58321 tccaagcaat gattctgaaa gtatctatga ggtggtgaca cgaccaaaca aaccagctgc
    58381 ttcatgggaa aatcctgaaa atcctcaaca ccaacaagct tttgtcagtc tgtatgacga
    58441 tgaaaaaggg gtgactgtat ccaacaaggg attgaatgaa tacgaaatcc ttggggataa
    58501 caccattgcc gtgaccattt tgcgtgcatc aggtgagcta ggtgactggg gctacttccc
    58561 aacgccagaa gcacaatgct tgcgtgagtt tgaagtcgaa tttgcgattg aatgccacca
    58621 agcccaagaa cgcttctcag cctatcgtcg tgccaaagcc ttgcagacac cgtttaccag
    58681 ccttcagctt gctagacagg aaggaagcgt ggttgcgact ggtagcctct tgagccattc
    58741 tgttctcagc atacctcaag tttgtccaac agcctttaaa gtggcggaaa atgaagaagg
    58801 ctatgtcctc cgttactata atatgagtca agaaaatgtg cgcatatcag aacatcaaca
    58861 aaccattctt gacttacttg agcgaccata tccagttcat tcaggaccat tggatccaca
    58921 agagattcgt acagaattca tcaaaaaaga agaaatttaa tttcaaaaag taaacatcaa
    58981 aagaaaggag gggcgaaaaa gtaagaacta actgctgatt cgcccctttt tatggtaaaa
    59041 acaatgacca ttgcaacgat tgatatcgga gggactggga ttaagtttgc cagtctgact
    59101 cctgatggga aaatactgga taagacaagt atttcaacgc ctgaaaactt ggaggattta
    59161 ctagcgtggc tagatcaacg cttgtcagaa caggattaca gtgggattgc tatgagcgtt
    59221 ccaggtgcgg tcaatcaaga gacaggtgtg attgatggct tcagtgcggt gccctacatc
    59281 catggctttt cttggtatga ggcgcttagc tcttatcagc tacctgtcca tttagaaaat
    59341 gatgccaact gcgttggact cagtgaacta ctagctcatc cagatcttga aaatgcagcc
    59401 tgtgtcgtga ttgggacagg gattggcgga gccatgatta tcaatggtag acttcatcga
    59461 ggtcgccacg gtctgggtgg agaatttggc tacatgacaa cccttgcccc tgctgaaaaa
    59521 cttaataact ggtcgcaact agcatcaact gggaatatgg tacgatacgt gattgaaaaa
    59581 tctggtcata ctgattggga cggtcgcaag atttaccaag aggccgcagc tggtaatgct
    59641 ctttgtcaag aagccattga gcgcatgaac cgcaatctgg cgcaaggctt gctcaatatc
    59701 cagtatctca tcgatccaga tgtcatcagt ctgggtggct ctatcagtca aaatccagat
    59761 tttatccaag atgtcaagaa ggctgttgat aactttgtcg atacctacga agaatacacg
    59821 gtcgcaccag ttatccaggc ctgcacctat cacgcagatg ccaatctcta cggtgctctt
    59881 gtcaactggc tacaggagga aaagcaatgg taagatttac aggacttagt cccaaacaaa
    59941 cgcaagctat tgaggtttta aaaggtcata tttctctacc agatgtggaa gtggctgtca
    60001 ctcagtctga ccaagcatct atctctatcc agggtgagga aggtcactat caattgacct
    60061 accgcaaacc tcaccaactc tatcgtgcct tatccttgtt ggtaacagtt ctagcagaag
    60121 ctgataaagt agagattgag gaacaagcag cttacgaaga tttggcttac atggttgact
    60181 gttctcgaaa tgcggtgctg aatgtggctt ctgccaagca gatgattgag atattggctc
    60241 tcatgggcta ctcaaccttt gagctttaca tggaagatac ttaccagatt gaaggacagc
    60301 cttactttgg ctatttccgt ggagcttatt cagcagagga gttgcaggaa atcgaagcct
    60361 atgcccaaca gtttgacatg acctttgtac catgcatcca gaccttggcc cacttgtcgg
    60421 cctttgtcaa atggggtgtc aaggaagtgc aggagctccg tgatgtagag gacattcttc
    60481 tcattggcga agaaaaggtt tatgacctga ttgatggcat gtttgccacg ttgtctaaac
    60541 tgaagactcg caaggtcaat atcgggatgg acgaagccca cttggttggt ttgggacgct
    60601 acctgatttt gaacggtgtt gtggatcgta gtctcctcat gtgccaacac ttggagcgcg
    60661 tgctggatat tgctgacaaa tatggtttcc actgccagat gtggagtgat atgttcttca
    60721 aactcatgtc agcggatggc cagtacgatc gtgatgtgga aattccagag gaaactcgtg
    60781 tctacctaga ccgtctcaaa gaccgtgtga ctctggttta ctgggattat tatcaggata
    60841 gcgaggaaaa atacaaccgt aatttccgca atcatcacaa gattagccat gaccttgcat
    60901 ttgcaggggg agcttggaag tggattggct ttacacctca caaccatttt agccgtctag
    60961 tggctatcga ggctaataaa gcctgccgtg ccaatcagat taaagaagtc atcgtaacgg
    61021 gttggggaga caatggtggt gaaactgccc agttctctat cctaccaagc ttgcaaatct
    61081 gggcagaact cagctatcgc aatgacctag atagtttgtc tgcgcacttc aagaccaata
    61141 ctggtctaac ggttgaagat tttatgcaga ttgaccttgc caacctctta ccagacctac
    61201 caggtaatct cagtggcatc aatcccaacc gatatgtctt ttatcaggat gttctctgtc
    61261 cgatacttga ccgacacatg acacctgaac aggacaagcc acacttcgct caggcggcgg
    61321 gaactattgc tgacattaaa gaaaaagctg gaaactatgc ttatctcttt gaaactcagg
    61381 cccagttgaa tgctatttta agtagcaaag tagatgtggg acgacgcatt cgtcaggcct
    61441 accaagcgga tgataaagaa agtttacaac aaatcgccag acaagaatta ccagaactta
    61501 gaagccaaat tgaagacttc catgccctct ttagtcacca atggctgaaa gaaaacaagg
    61561 tctttggttt ggatacagtt gacatccgta tgggcggact cttgcaacgc atcaaacgag
    61621 cagaaagccg tatcgaggtt tatctggctg gccagcttga ccgcatcgac gagctggaag
    61681 ttgaaatcct accatttact gacttctacg cagacaagga tttcgcagca actacagcta
    61741 accagtggca taccattgcg acagcttcga cgatttatac gacttaatac tcttcgaaaa
    61801 tctcttcaaa ccacgtcagc ttccatctac aacctcaaaa cagtgttttg agcagcctgc
    61861 agctagcttc ctagtttgct ctttgatttt cattgagtat aaaaacaaga acaccttgct
    61921 tggcgcaggg tgtttcgcgt gaaacagaag aattatctgg tttcaaatgc tacagttaaa
    61981 attagtaaaa caagaaatag aagctgaaaa gccagcatct gtagaagctt ggatcatttc
    62041 cgtcaaatta aaaaaggttg ctaccgacat atatagattc caaaaacaaa aacgttagcg
    62101 gaactagcag atgtgatttt atggagtttc gattttgcaa atgatcatgc tcatgcattt
    62161 ttcatggata atgttgagtg gagtcatgca gattcttact ttcttagctt tgttagtgac
    62221 gatgttgaag aacgttacat agaaaatgtc tatctggata gcctaagtgt caaacaaaaa
    62281 tttaagttta ttttcgactt cggtgatgaa tggtgttttg aatgctaagt gctgagagaa
    62341 atcgagacag aggacgaaga agcttatctc gtacgttcgg ttggaacgtt gccagaacaa
    62401 tatccagatt atgatggttt tgactatgaa gaatggtaaa attgaaatca gtctgtgtag
    62461 gcttagtatt tcaatagact tcctgcaaaa ctagaatcct agttcatgat tgataatgcc
    62521 agcaatcaaa ttcattcgta atccgaagcg tttacgatga tttcgatagg ttgttgaaat
    62581 cattttaaac gtttttactt tggcaaagat gttctcaacc ttgcttctct ccttagatag
    62641 cgcatggtta caggctttat cttcaactgt tagcggcttg agtttgctgg atttacgtgg
    62701 agtttgtgct tgaggatata tcttcatgag ccttcatagc gtgaaatttc tttttaccag
    62761 aatcattcgc taattctttt tttagggcga ttgattttta cttccgtcgc atcaatcatt
    62821 accgtgtcct cagaactaag aggagttctt gaaatcgtaa aaccactttg aacaagagtt
    62881 acttcaaccc attagctccg acggagtaag ttgctttcgt ggataccaaa atcagccgca
    62941 atttcttcat aagttcgata ttctcgcaca tattgaagag tggccataag aaggtcttct
    63001 aggcttaatt taggttttcg tccacctttt gcgtgtttaa gttgataagc tgtttttaat
    63061 acagctaaca tctcttcaaa agtcgtgcgc tgaacaccaa caagacgctt aaatcgtgca
    63121 tcagttagtt gtttacttgc ttcataattt tgtttcgcag ggagtctatt gactctttgg
    63181 taggtgtcaa tgtttttttc atctatcccg agaattattt tcccgccatt tgtatttgca
    63241 aatgctgagt aggtttccca gaaagactct ggaagattgt ttttagcttt tttgtattct
    63301 aaatcaaccc cttcaaattt taagtccata tttttccttt acatctgttt tttgtggttc
    63361 tggtatttgt tcaagttgag tgataatata gcgaattgaa tttcgagagt ttttactcag
    63421 ttaatttctt ttttaaccca ctttaatttc ttttttaaca cgtgttaaaa aagaaattaa
    63481 agtgggttaa ttttccttga cttaaaattt aaaaatgata tactgtgttt atggagagat
    63541 gacaatttat aaaatgtact actctattct actagataat gattgaataa aactttttat
    63601 aacaacggct agcaaagtta taattttata tctattagaa aataaatatg taaggaaatt
    63661 taaatgaaaa aaactacaat attatcatta actacagctg cggttatttt agcagcatat
    63721 gtccctaatg aaccaatcct agcagatact cctagttcgg aagtaatcaa agagactaaa
    63781 gttggaagta ttattcaaca aaataatatc aaatataagg ttctaactgt agaaggtaac
    63841 ataggaactg ttcaagtggg taatggagtt actcctgtag agtttgaagc tggtcaagat
    63901 ggaaaaccat tcacgattcc tacaaaaatc acagtaggtg ataaagtatt taccgttact
    63961 gaagtagcta gtcaagcttt tagttactat ccagatgaaa caggtagaat tgtctactat
    64021 cctagctcta ttactatccc atcaagcata aaaaaaatac aaaaaaaagg cttccatgga
    64081 agtaaagcta aaactattat ttttgacaaa ggcagtcagc tggagaaaat tgaagataga
    64141 gcttttgatt tttctgaatt agaagagatt gaattgcctg catctctaga atatattgga
    64201 accagtgcat tttcttttag tcaaaaattg aaaaagctaa ccttttcctc aagttcaaaa
    64261 ttagaattaa tatcacatga ggcttttgct aatttatcaa atttagagaa actaacatta
    64321 ccaaaatcgg ttaaaacatt aggaagtaat ctatttagac tcactactag cttaaaacat
    64381 gttgatgttg aagaaggaaa tgaatcgttt gcctcagttg atggtgtttt gttttcaaaa
    64441 gataaaactc aattaattta ttatccaagt caaaaaaatg acgaaagtta taaaacgcct
    64501 aaggagacaa aagaacttgc atcatattcg tttaataaaa attcttactt gaaaaaactc
    64561 gaattgaatg aaggtttaga aaaaatcggt acttttgcat ttgcggatgc gattaaactt
    64621 gaagaaatta gcttaccaaa tagtttagaa actattgaac gtttagcctt ttacggtaat
    64681 ttagaattaa aagaacttat attaccagat aatgttaaaa attttggtaa acacgttatg
    64741 aacggtttac caaaattaaa aagtttaaca attggtaata atatcaactc attgccgtcc
    64801 ttcttcctaa gtggcgtctt agattcatta aaggaaattc atattaagaa taaaagtaca
    64861 gagttttctg tgaaaaaaga tacatttgca attcctgaaa ctgttaagtt ctatgtaaca
    64921 tcagaacata taaaagatgt tcttaaatca aatttatcta ctagtaatga tatcattgtt
    64981 gaaaaagtag ataatataaa acaagaaact gatgtagcta aacctaaaaa gaattctaat
    65041 cagggagtag ttggttgggt taaagacaaa ggtttatggt attacttaaa tgaatcaggt
    65101 tcaatggcta ctggttgggt taaagacaaa ggcttatggt attacttaaa cgaatcaggt
    65161 tcaatggcta ctggttgggt taaagacaaa ggcttatggt attacttaaa tgaatcaggt
    65221 tcaatggcta ctggttggtt tacagtttct ggtaaatggt actataccta taattcagga
    65281 gatttattag taaacacgac tacacccgat ggctatcgag tcaatgctaa cggtgagtgg
    65341 gtaggatagg tatccattag ctaaatctaa tcattctgaa ctaaaaaatc ttcttacata
    65401 tgtaggaaga ttttttggat tctcaaaact agtttaaaag actacgctat ttaaaccaat
    65461 tttaagaatg gatatataag gatattcaga aatctagttg gtcaactttt gtattttgaa
    65521 tataccttag atggtgacga tgtcttggta tatctggtac tcacttacat attctaactt
    65581 attttaacta agatgcaact gtagttggtg aatttgctac aaatagtgta gaggcgttat
    65641 ttgaaaaata tacaaaaaag gaaccccaac ttacatttga gtttctctta cttttaatcg
    65701 tccgaatccg tattcttatt tcaaaaaatg tagtcattcg aatgatttct cttgcaatat
    65761 agtgaaatta acaaaaagaa aaaacgctga tcaagcgttt ttcttctgta ttgattcgta
    65821 ttgaatgctt acttcacttc tgtaaacaca acgtgtttgc gaagttttgg tgagtatttc
    65881 ttcaattgaa ggcggtctgg agtgttacgt ttgtttttag aagtaaggta caagcgttca
    65941 ccagattctt tgtgttcaag tgtaatattt acgcgcatgg tatctccctt ctattattca
    66001 gctgatgcag ctttagcgat tttacgtcct ttgtagtatc ctttaagtga tacacggtga
    66061 gaacgtgagt aatctccagt agtttcgtca aagtttacag atggagctgt tactttgtag
    66121 tgtgtacgac gtttgttttt cttcgctttt gaagtgcgac gtgcaggtac tgccattttg
    66181 atttctcctt taggtattta tattcgattc aatctactga ttttcatcaa ccatactagg
    66241 ataacacatt ttttttgtaa agtaaagtta cttgacaaaa aaagatgaaa aaattctcct
    66301 gtccgacttg tcagacagga gaagatgtta aatatcaatc tcaaatggtt cgtcaatggt
    66361 ttctgatacg tattttccgt ctttcttccg ttgcttgaca cactctgtga ggagatattc
    66421 gatttgccca ttgactgaac gaaagtcgtc ttctgcccat gatgcgagtg cagcgtataa
    66481 ctttgttgag agtcgaaggg ggatctgctt ttttttagct tcagccatct ttagtaaaga
    66541 cttcctgtgt tgacaattgg ttgtgcatca tgattgccac aaagaacgac aaggagattt
    66601 gaaaccatgg cagcttttcg ttcttcgtca agttctacca attccccttc attgagccgt
    66661 tctagtgcca tttcaaccat tcctacagca ccatctacaa tcatcttacg tgcatcaata
    66721 atggcagatg cttgttggcg ttgaagcata acggcagcaa tttctggagc ataagctagg
    66781 taagtgatac gtgcttcaag gatttccaag ccagcatctt ctacgcgact ttgaatttcc
    66841 tcacgaatac ggttagcaac aatttcgcta gagccacgga gactaccttc atctgcttgc
    66901 ccgtcacccg tagtatccac attaggagac acatcgtaag gatagatgcg gacaatatta
    66961 cggagggcgc tatcacattg caatgaaaga tattctttgt agttatcaac gttgaagact
    67021 gccttagcgg tatcgacaac tctccaagtt accgcgatac cgatttctac agggtttcct
    67081 aagcaatcat tgattttttg acgagaattg ctcaaggtca tgactttgag ggaaatctgt
    67141 ttcttgccaa tttcaagatt tacatcattg tcatttgatg atttagctcc taaaaaagga
    67201 gattttgtgc taacatcacc actttgtcca agtcgagtgt ggtttgcagg gttgactgct
    67261 acgctgaagg gattgacaaa gtaaaaacca ggttctttga tggtacctgt ataattacca
    67321 aagagtgtca gaaccagagc ttcctgaggt ttgacaactt ttaaaccagc atgagctaga
    67381 cctgcaatta cgattagtaa aggtccgata ataattccaa aaatgttttc cgaaccaaca
    67441 cccattataa atataaagat accaagtacg attgtcaact caatgagaat caatgcgaat
    67501 acaccatttg gttttgaatt gattagtttt tcagtcataa gaatgacctc ccattatttg
    67561 atatctaaat gatatcactt tgtttttaaa agtcaataga aagttgaaaa taatcactaa
    67621 aaactttcag cccaataatt tcttttaaaa ggtgagatta tattgtgctc aaatactctt
    67681 ttattcttat aatttttaca ctataattgt agttagaaag gaagagaaat gtttgattat
    67741 agagcactag ttattttgat gactttgatg gatcattgtg agctatcatt atatgaatta
    67801 tctgttaagg tgagcttacc tataaaggaa gtcaaagaag gaatagatta tttagtgcct
    67861 tatctagcta ataaagggat agtgctggat aaaaaacaag gtcgctatag tttatcaaat
    67921 cgtacgaagc agtctttgac agatattatt aagtcggatg aattggtttt accaaagtcg
    67981 actcgcttag ctttaatcta tctttacact ttttgccgat tagattttat atcgaataat
    68041 cattaccaag actttttgaa agtaagtaag aatacaacct tatctgatat tcaatcatta
    68101 agaaagatta tgttagataa tgatttggag ctagggtaca gtagagcaaa aggttatact
    68161 ttacacggtt cagagtggaa taagcaccgt ttagcttttc aaatggttag tgagttgctg
    68221 gaatcctcca tagggatttg gggtttggat tatgttttat ccagttgggg gtattcatta
    68281 acttatgatt tgattgatca ggtagttaaa gattattatg agaagctaca gctagtacct
    68341 attgttaatc aattaaaagt ttaccttttc ggtttagtat tcattctgtg taggtatcaa
    68401 agggatgttg aaagagtatg tctttcagag acattagtat ctcctgttat tcaagatata
    68461 accactattt tattggatac agtggttgat ttgggaatta tagatacggt gttttctgag
    68521 gatgattatc gctatatcac agttttatta tcaagttgct ttgaaggtga agtagatgtt
    68581 gctccggttt actttaatca attaacagag gctattataa gtagaatgga agatatttct
    68641 ttgttacatt ttaaacaaag ggaaggattg agagaaaatc ttcgccgcca ccttataccg
    68701 gcttactata gattaaagtt cggcctacct agttcaaatg aatatgtatt gcatgttaaa
    68761 gaacattatc ctgatttatt tgaattagtc aaagattctt tgatgccctt gatggacgct
    68821 attgacaatc ccatacctga tagtgaaaca gcatattttg ttatccattt cggaggttat
    68881 ttaaagaaag cagatacttt gcctcaaaaa tgctataaag cagcaatcat ttgtcctaat
    68941 ggtgttagtt cttcattgat gttaaaagag aatctattag cattatttcc tcaaattgag
    69001 tttataggaa cctcaaagat tgatgattta caggtgaaag ctagtagtga ctatgatatg
    69061 gttttttcta ccataaaggt ggagacagaa aagccaaatt atctagtttc ggttatgatg
    69121 actgaagagc aagcaataca actagtagaa ctagtgttaa aagattttcc gaatttagag
    69181 tatggagatt ttgagattga acaaatcctg aatattgtca aaagatatgg aattattaca
    69241 caagaattgg aattaagatt ggcgttaaag aattatcttt atcaaaaaaa tgatagaaag
    69301 gaaattgtac cagtgctaga acaacttatt accaaagaaa cctatcaggt tagttcgcaa
    69361 aaattaggat ggaaggaggc gattcgttta gcagctaaac cgcttttgga tcaagataag
    69421 ataactgaga actaccctga ggcaatgatt caaaaagtag aagagtttgg accttttatt
    69481 aatttaggga agggagtagc aattcctcac gctcggccag atgaaggtgt gaatgaaata
    69541 ggaatgtcaa tgttagtttt ggaagaaccg atttatttat tggataatcc agaacaagag
    69601 gtaagattgt tgatttgtat tgcagccatt gataatgaga gtcatttaaa ggctttgtca
    69661 catttaacaa caattttaag agataaaaat catgttcaaa ctttaatatc atcaaaaaac
    69721 tatgatgaca ttaaaatgat aattaaacag gaggattaga taatgttaaa aattggtaca
    69781 gcttgtggtt caggattagg ttcaagtttt atggtacaga tgaatattga atctgtattg
    69841 agtgatttga atgtttcgga tgtagaagtt gaacattatg atttaggtgg agcagatcca
    69901 aatgcagctg atatttggat tgttggtcgt gatctagctg attcagctag tcatcttgga
    69961 gatgttcgta tcttaaatag tattattgat atggatgaac tacgagaatt aattactaaa
    70021 ctttgtgaag aaaaaggact tatataggag gctagcgtca tgatgaagtt catattggat
    70081 attgttagta caccagctat tttagtagct ttaattgcaa ttttaggatt agttcttcag
    70141 aagaagaaat tacctgatat tattaaaggt ggaattaaga cctttgttgg tttcttagtt
    70201 gtatctggtg gtgcaggaat tgtacaaaat tctttaaatc catttggtac catgtttgag
    70261 catgcttttc atttatctgg cgttgtgccg aataatgaag caattgtagc tgtagcttta
    70321 acaacatatg gctcagctac tgcaatgatt atgtttgcag gaatggtgtt caatatctta
    70381 atcgctcgtt ttactcgatt taaatatatt tttttaacag ggcaccacac tctatatatg
    70441 gcatgtatga ttgcggtcat tttatcagtt gctggcttta ctagcttgcc tctcatctta
    70501 ctaggaggat tagcactcgg tattattatg agtatttccc cagcatttgt gcaaaaatat
    70561 atggttcaat taactggaaa tgacaaggtg gctttaggtc atttcagttc tttgggatat
    70621 tggttgagtg gttttactgg tagccttatc ggtgacaaat caaaatcaac agaggacatt
    70681 aaatttccaa agagtttagc ttttttacgt gatagtactg ttagtatcac tttatctatg
    70741 gcagttattt acattattgt agctatcttt gcagggtcag aatatataga aaaagaaatc
    70801 agtagtggta caagtggtct agtttatgct ttacaattag caggtcaatt tgcagcaggg
    70861 gtatttgtta ttttagcagg tgttcgcctt attttgggcg aaattgttcc agcctttaaa
    70921 ggtatttcag agcgtcttgt acctaattca aaacctgctt tggattgtcc gattgtttat
    70981 acttatgcac ctaatgcagt tctaattgga tttatctcta gttttattgg tggtttagta
    71041 agtatggcaa ttatgattgc ttcaggaacg gttgttatct taccaggcgt tgtgcctcat
    71101 ttcttctgtg gagcgactgc aggtgttatt gggaatgcat ctggtggtgt tcgtggagcc
    71161 actattggag catttttaca aggtatttta atcagttttc tcccagtctt tttaatgcca
    71221 gttttgggag gactcggttt ccaaggatca actttctcag atgcagattt tggtctatca
    71281 ggaattattt taggaatgtt aaatcaattt ggctcacaag caggcattgt gattggtctt
    71341 gttcttattt tagcagttat gtttggagta tcctttatta aaaagccatc tgcaaaggag
    71401 gaataaggga tgattttaag taaaaataga gaagatgagt taagaaaatt tgcggctaac
    71461 atccgattaa atactcttag aacattgaat catcttggat tcggacatta cggaggaagt
    71521 ctgtctatcg tagaagtttt agcagtgctt tatggtgaaa taatgccaat gactccagaa
    71581 acatttgcag cacgagatag agattatttc atattatcaa aaggtcatgg aggaccagct
    71641 ctatacagta cactctattt gaatggtttc tttgacaaag aattcttata ttctttaaat
    71701 acaaatggaa ccaaattacc gtctcatcct gatagaaatc taacgccagg catagatatg
    71761 acaacgggct ctttaggaca aggaattagt gttgcaactg gacttgcata tggtcagaga
    71821 ataagaaaga gtccctttta tacttatgct attgttggag atggtgagtt aaatgaggga
    71881 caatgttggg aggctataca gtttgcttct catcaacagt tatccaactt aattgtattt
    71941 gttgatgata acaaaaaaca attagatggt tttacaaagg atatttgtaa tccaggtgat
    72001 ttcgtagaaa aattttcagc atttggattt gaatccatta gggtcaaggg ttcagatatt
    72061 agagaaattt atgaagggat tgtccaatta aaacagtcaa ataattcatc acctaagtgc
    72121 attgtattag atactattaa aggtcaaggg gttcaagagc tggaagaaat gaaatccaac
    72181 catcatcttc gccctactgt agaggagaga caaatgttaa cttcagttgt agaaagatta
    72241 agtcaggaat tggaggaaac agaatgatga gaagcacgaa agaattacgg catgtatata
    72301 gagacttcct tttagaggct aatcaaagtt attctgatat agtagtctta gaagccgatt
    72361 tgtcaagttc gatggctact aataatcttg aaaaggattt tggagaccgt tatgtgaatg
    72421 ttgggattat ggaagcagaa atggtcggcc ttgcagcagg cttgtctatt caggggttta
    72481 gaccttatct tcatacattt ggtccttttg cttcacgaag agtatttgat caattattta
    72541 tttctcttgg atacgcacaa ttggatgcca ctgtgattgg atcagatgca ggagtaactg
    72601 cagaaatgaa tggtgggaca catatgccat ttgaagaaat tggattgtta cgtttaattc
    72661 ctaaatcgat catttttgaa gcaactgatg atatccaatt tcgtgaaata ttgaaccaga
    72721 cattagactt aaaaggacta aaatatattc gaacaattag aaaagctcca gttcctgtgt
    72781 atcaaggtgg agaagatttt tctaaaggct acattgagtt aaggcatggt gaagatcttg
    72841 taatcgttgc ttctggtata atggttgctc caagtattcg agttgcagat gaactgtcta
    72901 aattaggtta ttcagtaagt gtgatagatt tatttagaat caaaccgata ccagaacaga
    72961 taaaaacaat gttaagtgga aaaactatat ttactgtaga aaaccacaat cagataggtg
    73021 gaattggcag ttctttatgt gaattattct ctgatgatgg aatgacaaaa attcatcgga
    73081 tgggtgttca agaaagattc ggtcaagtag ggaaaatgga ttatcttctt aatgagtatg
    73141 gtttgagtga atcgaatata aaagagaagg ttctagaaat ttataatgca agatagatgt
    73201 taaatacact tatctgaaag aatttctgta aaaattacag tacgttattt aaagaaagcg
    73261 gattaaaaag catattctgg tcatcagaaa gtgcactaat ccgctttgtt gtttttaatt
    73321 ttaaatattt cacatgtgta tagaattttc tgaaaattca agatttttat tctgttcttc
    73381 atgcgaaaat tgtgctataa tagtaaaaac tgaaatggga gggataagat gactgaatta
    73441 gataaacgtc accgcagtag catttatgac agcatggtta aatcacctaa ccgtgctatg
    73501 cttcgtgcga ctggtatgac agataaggac tttgaaacac cgattgtggg agtgatttcg
    73561 acttgggcgg aaaatacacc atgtaacatt cacttgcatg atttcgggaa actggctaaa
    73621 gaaggtgtca aatctgcagg cgcttggcct gtacagtttg gaaccattac cgtagcagac
    73681 gggatcgcta tgggaacgcc tggtatgcgt ttctctctaa catctcgtga catcatcgcg
    73741 gactccatcg aggcggctat gagtggtcac aacgtggatg cctttgtcgc tatcggtggc
    73801 tgtgacaaga acatgcctgg atctatgatt gctattgcta atatggatat cccagctatt
    73861 ttcgcctatg gtggaactat tgcaccggga aatcttgatg gtaaagatat cgacttggtt
    73921 tctgtctttg aaggtatcgg aaaatggaac cacggtgaca tgacagctga ggacgtgaaa
    73981 cgtcttgaat gtaatgcctg ccctggccct ggtggctgtg gtggtatgta tactgctaat
    74041 accatggcaa ctgctatcga agttctaggg atgagtttgc cagggtcatc ctctcaccca
    74101 gctgaatcag ctgataagaa agaagatatc gaagcagcag gacgtgctgt tgttaagatg
    74161 ttggaacttg gtctcaaacc atcagatatc ttgactcgtg aagcctttga agatgctatt
    74221 actgtaacga tggctctcgg tggttctaca aacgccactc ttcacttgct cgccattgcc
    74281 catgccgcaa atgttgactt gtcacttgaa gacttcaata cgattcaaga acgtgtgcct
    74341 cacttggccg acttgaaacc atctggtcag tatgtcttcc aagacctcta cgaagtcggt
    74401 ggtgtccctg cggttatgaa gtacttgttg gcaaatggtt tccttcacgg agatcgcatc
    74461 acatgtactg gtaagactgt agctgaaaac ttggctgact ttgcagactt gactccaggc
    74521 caaaaagtta tcatgccact tgaaaatcca aaacgtgcgg atggtccgct tatcatcttg
    74581 aacgggaacc ttgctcctga cggtgcagtt gccaaggtat caggtgttaa agtgcgtcgt
    74641 cacgttgggc cagctaaggt ctttgactca gaagaagatg cgattcaggc cgttctgaca
    74701 gatgaaatcg ttgatggcga tgtagtcgtt gttcgttttg ttggacctaa aggtggtcct
    74761 ggtatgcctg agatgctgtc actttcttca atgattgttg gtaaaggtca gggagataag
    74821 gtggccctct tgacggacgg acgtttctct ggtggtactt atggtctggt tgttggacat
    74881 atcgctcctg aagctcagga tggtggacca attgcctatc tccgtaccgg cgatatcgtt
    74941 acggttgacc aagataccaa agaaatttcc atggccgtat ccgaagaaga acttgaaaaa
    75001 cgcaaggcag aaacaacctt gccaccactt tacagccgtg gtgtcctcgg taaatatgcc
    75061 cacatcgtat catctgcttc acgcggagcc gtgacagact tctggaatat ggacaagtca
    75121 ggtaaaaaat aaactcatac tcgaaaatct cttcaaatca cgtcaacgtc gccttgccgt
    75181 aggtatggtt actgacttcg tcagttctat ccacaacctc aaaacagtat tttgagctga
    75241 cttcgtcagt tctatccata acttcaaaac agtattttga gctgacttcg tcagttctat
    75301 ccataacttc aaaacagtgt tttgagcaac ctgcggctag ttttctagtt tgccctttga
    75361 ttttcattga gtatcaaaaa gcaagccatt tttggcttgc ttttttcatc tttaaaagtg
    75421 attggcctgc ttaacgaggt ggtagtccaa gggcaatacg gccatagcga ctgattcgtg
    75481 tgattttcca agcaggcgac caggtaactt caaccttgat atctttgata ccctcgattt
    75541 gtttcagacc tgccacaatt tcaataggca ggctttcggc gcaatcacag gcagtatcgg
    75601 tgaaggtcat gacaatcttg cagagccccg tttcatccag attgatttca taaatcagac
    75661 ctagattgta aacatccaat tccacatctg tatcaaaaac tttctctagt ttttcgataa
    75721 tttggtcttg caaggccaaa gcacggtcat tgattttgat atcgtctctc atagcagtcc
    75781 ctccacgtga taaatatcct ctattttctc ataattctga caatttggca agtttttgat
    75841 gaattttctg aaaaatatga taaaatgaag aaaatacgga atcaagggga agtctatgga
    75901 gtagattgga aaagtcttta gacaattacg agaatcaaga aatatctcac tgagacaagc
    75961 aaccggagga caattttcgc cgtctatgtt gtcccgtttt gaaacaggtc agagtgagct
    76021 ttcggtggaa aagtttctat ttgctctgga aaatatatct gccagtgtgg aggagatcct
    76081 ctttctggcg agaggtttcc agtatgatac agattctgag ttgagaaaag aaattacaga
    76141 tgtcttggaa ccaaagaata tagcacctct tgaggactta tatcgcaggg agtatcaaaa
    76201 gcatgcccat tctcacaaca aacagaaaca tattctaaat gccattatga tcaagtctta
    76261 tatgaagagc atagatgaaa gggtagagtt aacagcagag gaaggaaaag tccttcatga
    76321 ttatttgttt tctaccgaga tctggggaat ctatgaactc aatttatttt cagtcagttc
    76381 tccattttta tctgtttctc tttttactag atatgtacga gaaatggtac gtaaatctga
    76441 ttttctaatg gaaatgtctg gcaatcgaaa cctttttcat actatactat tgaatggctt
    76501 tttagctagt attgagtgtg aagaatttac caatgcctat tattttaaac gtgttatcga
    76561 agagcatttc tacaaggaaa atgagaccta tttccgaatt gtttatctgt gggcagaagg
    76621 tttccttgat agcaagcaag gtagagtcaa ggaaggtcag aaaaagatgg aggatgctgt
    76681 ccgtattttt gagatgcttg gctgtaataa atctgccgaa tactatagaa atacgaccga
    76741 atgttgaata tctgcaaacc aagaaaaaat ttgaagcgat agaactgttg ccctctctca
    76801 ggtcattaca aaagttctat cgtttttttg ctcattttgt ttgttgcata tattcaaaag
    76861 aatcgtttcg caaattcata agtgctatac taaagctatt cttgatgtag aacttagaac
    76921 aaggagggag attatctatg aaactattgt ttagaaatcc agcttataga attttgactt
    76981 tatcacgctt cttcaatgct tttggtgctt cgattttcaa cctggtcttt atcgtctatg
    77041 catcgacctt gtcacaagca tcttttgctg ttgctatggc gaatattgtc atgattcttc
    77101 cgaccctctt tacagttttt gcagggattc gggcagatta cacgagggac aaggtcaaat
    77161 ggatggtcta tagcggtttg tttcaggcgg ttctattttt tctagcagcc ctagttgttc
    77221 agcaagctag cctctttgcc ttttctagcc tgtgtttgat caatgtcatt agtgatatca
    77281 tcagtgattt tgcaggtggc ctgcgtatgc ctcttattaa ggaaaaagta gctgaagatg
    77341 atctgatgga ggcttattct ttttcacagt tcatcaccta tatttcagct attggtggtc
    77401 aagctttcgg agtctggctc ttagctctat cggtcaacaa tttttctctc gttgcgggaa
    77461 tcaatgcctg ctttttccta gtatcagcca ctatcctctt tttaggaaaa agcaaattga
    77521 gcctgtcaat gtcatctgct gatggtgaaa acttaaaaaa tgagaagctt tctatcaaag
    77581 accagttcct aacaatttac cgaaatttac gtctcgtttt tcttaaaagt ggacagaaaa
    77641 actttggttt tatgctcttt gctgtcttgc ttattaattc cttgggtggc gctttgggtg
    77701 gaatttataa tatcttcttt ttgagccatt ctctcttgaa tttttcttat acagaggcac
    77761 tatttatcaa tcaattctgt gttttagtag caatcatcat cagtagcctt acgggcaatg
    77821 attattttgg gaagcagtcc ttgcctagat tgatgatgtg ggcgaccgta ggacttagtc
    77881 tagttggttt ggctaattta ttcaatcaag tcgtgcttgg tttgctattt ctcttcttta
    77941 ctctgtatgt gtctggtaaa gttcaaccaa agattagtgc catgctcatg aaaaatctag
    78001 ctccagaggt tctagctcgt actagtaatt ttttcggtct attgtttacc ttatccatac
    78061 ctgtgggaac agcttgtttt tcactagtag ccgtatggaa catgcagttg acttggatgc
    78121 tatttgttgg tttttccttg ctagctattt ttttgacaat tcttaatctc aaaaatgata
    78181 tttgaatcct aattttttct cactgtttta atccctctat ttatggtaaa ataagactat
    78241 taagtttaaa gaggattccc tatgaaatta caaaaaccaa aaggaacgca ggatatttta
    78301 cctgctgagt ctgctaagtg gcagtacgtt gagggctttg cccgtgaaat tttcaaacgc
    78361 tacaactacg cagaagtgcg tacgcctatt ttcgagcatt acgaggttat cagtcgctct
    78421 gtcggagata caacggatat cgtaaccaag gaaatgtacg atttttatga caagggtgac
    78481 cgtcatatta ccctccgtcc agaaggaact gcgcccgttg tccgttccta tgtggaaaat
    78541 aaactcttcg ccccagaagt gcaaaagcca agcaagttct actatatggg acctatgttc
    78601 cgttatgagc gtccacaggc agggcgcttg cgccaattcc accagattgg tgttgagtgt
    78661 tttggctcta gcaatccagc taccgatgtg gaaacaatcg ctatggcagc ccattttttg
    78721 aaggaaatcg gtattcaagg tgtcaaattg cacctcaaca ctcttggaaa tcctgagagc
    78781 cgtgcagcct accgccaagc cttgattgac tatttgacac cgctcaagga gaccttgtct
    78841 aaggatagcc aacgtcgctt ggaggaaaat cctcttcgtg tcttggactc taaggaaaaa
    78901 gaagacaagg tggcagtaga gaatgcgccg tctatcttgg actttcttga tgaagaaagc
    78961 caaactcatt ttgatgctgt gcgtcagatg ttggaaaatc ttggagtaga ttacatcatc
    79021 gataccaata tggtgcgtgg tctggactac tacaaccaca ccattttcga gtttatcaca
    79081 gagattgagg gcaatgactt gacagtctgt gcgggtggtc gctacgatgg tttggttgct
    79141 tactttggag gccctgaaac tgctggattt ggttttgggc ttggtgtaga gcgcctgctt
    79201 ctcatccttg aaaaacaagg cgtggccctc cctatcgaaa acgccctaga tgtctatatc
    79261 gcagtcttgg gtgatggagc aaatgtcaaa gccctagaac tagtccaagc tcttcgccaa
    79321 caaggtttca aagcagagcg tgattacctc aaccgtaagc tcaaagctca gttcaagtca
    79381 gcagatgtct ttgcggctaa gaccctcatc accctaggag agagcgaagt cgaaagcgga
    79441 caagtgacgg tcaagaacaa ccaaacccga gaagaagtgc aagtgtcact tgagacaatc
    79501 agccaaaact tctcagaaat ctttgaaaaa ctaggatttt atactcaatg aaaatcaaag
    79561 agcaaactag gaagctagcc gcagattgct caaaacactg ttttgaagtt atggatagaa
    79621 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
    79681 accataccta cggcaaggtg aagctgacgt ggtttgaaga gattttagaa gagtattaat
    79741 gatagataaa gtggtcagga acttactcct gacctttttc ttttgcaaaa tgacaaaaat
    79801 cataaacttt ttgacaacta taattgtcaa aaaagaaaaa gatatgttac aatgaattca
    79861 agttaagaaa taggaagcag aaaggagtta taatgtgggt actaggattt atactattta
    79921 tgattttctt ttattctaat aattctaaaa aaatcaagaa actagagaat aaaatcaaaa
    79981 aacttgagcg aaaagagaaa ggaaacgcag aaatgtcgag attattacaa gaaatgattg
    80041 gaaaggaacc aattataacg ggagtgtata ttgggccaga taactgggaa gttgtggatg
    80101 ttgatgagga atgggtcaaa ctacgtagtg ttgataatac gggaaaagaa aaattcaagt
    80161 tgcaacgtat tgaagatatc caaaccgttg aatttgacgg agagtaggtg tgtaacgtgc
    80221 aactaaaaaa tcgtctaaaa gagcttcgag ctcgcgatgg tctcaatcaa accgacctag
    80281 ccaaactggc aggggtttcc agacagacca ttagcctact agaacgggat gagtacaccc
    80341 catccattat cattgccctg aaaatatctc aaattttcaa cgaaacagtc gaatcggtat
    80401 ttcgtttgga ggaggacgag tgatgaacaa gtataaagtg atttattatg tagtggtcat
    80461 agctttatta gtcagcgtat ttctactgat tgggatggac ctaagctggt ttaatcccta
    80521 tcaaagcgac caatttgttt gggtctactt tgctctcatc ccagtaactg aatggattga
    80581 aaagaaatcc aaaaatctag caagtgaaaa aggagaatga atatgaaaaa gaaacgtaga
    80641 ttgttatttt tgatgtctat tgtcttgggg gggttcttgg gcatgtttgt agggatgttt
    80701 aaggcacgtg tcgaatccca cgaaattatt ttagatgtaa aagccttgat gccatggata
    80761 tcagctattt gtttactgat aggtttcatt agtatgtttt tgactttcaa tttcttaaag
    80821 aaaagcagaa aatttcattc cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc
    80881 tattatgtgc aaatgtatcg gaatcttgag tttggaacca ttgcttttaa tattacaggt
    80941 gtagcgattc cattggctat ttttatttca ttaagtgagg tgattatatt gcatacaaac
    81001 cctcaaacat ttttcctttc tttcttactc tttgtggtat tcttagtcgc tcaaaaatct
    81061 ctttttaaaa ccattgcgat tgttcgtcag tttgatttgg aatttttcgc tacaccaaag
    81121 gatgtcttga actatataaa ttcttatgat gaaggggagc gtcaggctaa tttggaacag
    81181 agttttcgaa ttttattcca attacaccaa tatgtcttac cagccttata tatttttctt
    81241 attatcattt ctttcttgac aggagagatt cagttactag ctttcttgct tgtaggagcc
    81301 atccatgttt atatcaatgt gatgcagtta cctatggtaa aacgttattt caaataaagg
    81361 agttatctat gaaattactt aaaaaccttg gctggattct tctagccctt ctatcctttt
    81421 tctttatcta tggctttatt caggggctcg cgactgcgtc gcttgcttta ggcgcttcac
    81481 cctatgctgt tactctactc tatgtggtct tggctggagt atatgtgtac ggcatttaca
    81541 aatggtatca gaaagctcct gtttatattg agaagagcgg ctttaaccga tttatttggc
    81601 ttcctgcctt ggtttggttc ttatctctgg tcgttcaatt cttcttgcca gatgatcctt
    81661 cagtaaatca gcaaatagcg acagacttga ccttgtctca accacttttc tcattctttg
    81721 ctgtggttat ttttgctcct ttgacggaag agattgtttt tagagggatg ttagcacgct
    81781 atctctttcc taagcaggac aatagtaaac gaaccctgat ttttcttctg gtatctagtc
    81841 ttctatttgc cttgattcat tttccaggtg atgtgcaaca attttttgtc tattttagcc
    81901 ttggttttag tttgggtttg gcttacgtta gcagaaaagg tctggtctac agtatttctc
    81961 ttcacgcttt gaataattta gtcggctttt tgatgattct catgctataa tagagtcagg
    82021 aggtcacatg aaacgagtaa ttttattagc agtgattcag gcagtcgttc tatttttcat
    82081 cattggagcg ctagcttatg ccttcaaagg cgatttcttc tataactatc tagcagttgt
    82141 ctttgctcct attgcaggtg tactgcgttt tgggacggct tacataacgg aaattgtctt
    82201 gcctcgaaag gcagccgaaa tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa
    82261 gagtccggtg aagttcatcg gatttttgta ttatactcaa tgaaaatcaa agagcaaact
    82321 aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgt
//
LOCUS       DAVLHB010000004        79960 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLHB010000004 DAVLHB010000000
VERSION     DAVLHB010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.004"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..1103
                     /locus_tag="VXE36_000256"
     CDS             <1..1103
                     /locus_tag="VXE36_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0778627.1"
                     /translation="IFNEDIPKEWFYLMEKRLEKLNCEILNIEIDAEKVKYFSTPDEH
                     IKYMTYFRYFIAEFVKEDRAVYLDCDMVIHGNINPLFQKDFEGNYIIAVPDGWYKNIF
                     NAGMMMVNVHKWKTDNICQNLLELTAEKHQEIYGDQGVLNLLFENKWKKVSPHYNFMV
                     GLDTLGYWAQKPEWFLNSWDENYKPAIIHFEGKDKPWNDSLKTRYRELWWFYNGLDWQ
                     TILSQVDNKPTTFSEIATVSLFHTAIFTDTHELEHIEYLVEKLPNVHFHIFAHSYFGP
                     RVQALNHFLNVSLYPNYTPYQSQEVLSKLDFYLDINHNHEIDNIISKVHNLSKPIFAF
                     ENTSHDTNNRSQILPSTEPKEMVEAIRQFIGE"
     gene            1108..1983
                     /locus_tag="VXE36_000257"
     CDS             1108..1983
                     /locus_tag="VXE36_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0778628.1"
                     /translation="MADELISIIVPIYNVEKYLRQCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYIAFVDSDDWLESDYLE
                     VLYSKIVEYDTDFVIGSYKKFSMSDNCYYMHVWEQDYYEKIWTSQELITVLPNIENYD
                     SSYTVSWGKLFKRFLFDEVLFNEQRRFGEDFECSFKLYLTMTSCLYIHRELYNYRVHS
                     ESMVGKVRTERQLMDDVEIRLGRIPFLIGRGIDSTPYIAEIKRLIQWRLDTKSDVEEG
                     ESNALCMYREILRNL"
     gene            1992..3197
                     /locus_tag="VXE36_000258"
     CDS             1992..3197
                     /locus_tag="VXE36_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0778629.1"
                     /translation="MKKAIVLGADNHYMDKVETTIKSICSKNKEVKFYVFNSDLPTEW
                     FQLMDKRLSVLGSEIVNVKVTESLINQFHLPTPHLSSATYLRYFIPTIVFEKRVLYLD
                     SDIIVTADLTSLFEFPLDGCPLAAVPDIPNTSEGFNSGVLLIDTDRWREDDIQNQLLN
                     LTIKHHEHVYGDQEILNMLFKDRWKKLSLSYNLQVGYDTYRHSLGDNEWYHLFEGIPN
                     IIHYTTQNKPWSHYRFNRFRDIWWFYYGLNWNDILLDNQILQENFEKLIKPITCHASI
                     FTNTGDIEGLPYLLEQLPNVQFHIAAPTYFSPNIVELQRYSNLYIYPCVDPKMKETLI
                     NQTNFYLDINYGPALDDALQEIVRQGNPIYSFESASHFSNGENQVFAVDNVDEMVKSI
                     QNKLSESHR"
     gene            3237..4247
                     /locus_tag="VXE36_000259"
     CDS             3237..4247
                     /locus_tag="VXE36_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0778630.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARSLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            4257..6710
                     /locus_tag="VXE36_000260"
     CDS             4257..6710
                     /locus_tag="VXE36_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEV0778631.1"
                     /translation="MIKTIVLAGDRNYIRQLETIIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNTGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLTANRYRDLWWEFHDLEWSQILQHHMGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYVIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLAYHLSRKGYQVLDIGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IEDETYNSQILVDLSKREV"
     gene            6707..7598
                     /locus_tag="VXE36_000261"
                     /pseudo
     CDS             6707..7598
                     /locus_tag="VXE36_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653909.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            7623..8843
                     /locus_tag="VXE36_000262"
     CDS             7623..8843
                     /locus_tag="VXE36_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEV0778632.1"
                     /translation="MLQDKKSVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            8852..10048
                     /locus_tag="VXE36_000263"
     CDS             8852..10048
                     /locus_tag="VXE36_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0778633.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNSGVLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            10048..10953
                     /locus_tag="VXE36_000264"
     CDS             10048..10953
                     /locus_tag="VXE36_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0778634.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIE
                     TLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFN
                     SSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRS
                     GSIMRTEFDLSWARDIVEVFSKKISDCILAGLDVSVLRIRFVNLLKDYKQTLEYHQLT
                     DTEEYKDICFRLKLFFDAEQRNGKS"
     gene            11010..12227
                     /gene="secY2"
                     /locus_tag="VXE36_000265"
     CDS             11010..12227
                     /gene="secY2"
                     /locus_tag="VXE36_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEV0778635.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSYSKKLGLSSTAIEIQDRR
                     KMYLTLLIAVIQSLAVSLSLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSIVLNIPQDVIETFKLVYIPTGIVVLLVFMTIIFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            12237..13817
                     /gene="asp1"
                     /locus_tag="VXE36_000266"
     CDS             12237..13817
                     /gene="asp1"
                     /locus_tag="VXE36_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEV0778636.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            13801..15336
                     /gene="asp2"
                     /locus_tag="VXE36_000267"
     CDS             13801..15336
                     /gene="asp2"
                     /locus_tag="VXE36_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEV0778637.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMNWYHFYPNSSEALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            15333..15773
                     /gene="asp3"
                     /locus_tag="VXE36_000268"
     CDS             15333..15773
                     /gene="asp3"
                     /locus_tag="VXE36_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEV0778638.1"
                     /translation="MIITQRQSIHWGEVGGTYMYGTTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKVKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            15766..18138
                     /gene="secA2"
                     /locus_tag="VXE36_000269"
     CDS             15766..18138
                     /gene="secA2"
                     /locus_tag="VXE36_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEV0778639.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKEYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDMIYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            18150..19661
                     /gene="gtfA"
                     /locus_tag="VXE36_000270"
     CDS             18150..19661
                     /gene="gtfA"
                     /locus_tag="VXE36_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEV0778640.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNANKVDFFI
                     VSTDRQREVLQEQFAKYTPHQPKIVTIPVGSIDSLTESSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEARKEIPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            19654..20991
                     /gene="gtfB"
                     /locus_tag="VXE36_000271"
     CDS             19654..20991
                     /gene="gtfB"
                     /locus_tag="VXE36_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEV0778641.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYEHALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLRYPNVALY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            20993..21172
                     /gene="asp4"
                     /locus_tag="VXE36_000272"
     CDS             20993..21172
                     /gene="asp4"
                     /locus_tag="VXE36_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEV0778642.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            21177..21401
                     /locus_tag="VXE36_000273"
     CDS             21177..21401
                     /locus_tag="VXE36_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEV0778643.1"
                     /translation="MIDILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFILLLTFMVITYK"
     gene            21462..21539
                     /locus_tag="VXE36_000274"
                     /pseudo
     CDS             21462..21539
                     /locus_tag="VXE36_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21682..22635)
                     /locus_tag="VXE36_000275"
     CDS             complement(21682..22635)
                     /locus_tag="VXE36_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0778644.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(22703..23921)
                     /gene="sstT"
                     /locus_tag="VXE36_000276"
                     /pseudo
     CDS             complement(22703..23921)
                     /gene="sstT"
                     /locus_tag="VXE36_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            24060..24620
                     /locus_tag="VXE36_000277"
     CDS             24060..24620
                     /locus_tag="VXE36_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEV0778645.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            24677..25585
                     /locus_tag="VXE36_000278"
     CDS             24677..25585
                     /locus_tag="VXE36_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0778646.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            25537..26127
                     /locus_tag="VXE36_000279"
     CDS             25537..26127
                     /locus_tag="VXE36_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0778647.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            26130..27236
                     /gene="yqeH"
                     /locus_tag="VXE36_000280"
     CDS             26130..27236
                     /gene="yqeH"
                     /locus_tag="VXE36_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0778648.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            27450..27761
                     /gene="yhbY"
                     /locus_tag="VXE36_000281"
     CDS             27450..27761
                     /gene="yhbY"
                     /locus_tag="VXE36_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0778649.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27813..28442
                     /locus_tag="VXE36_000282"
     CDS             27813..28442
                     /locus_tag="VXE36_000282"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0778650.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            28442..29035
                     /gene="yqeK"
                     /locus_tag="VXE36_000283"
     CDS             28442..29035
                     /gene="yqeK"
                     /locus_tag="VXE36_000283"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0778651.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            29036..29536
                     /locus_tag="VXE36_000284"
     CDS             29036..29536
                     /locus_tag="VXE36_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0778652.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     AMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            29549..29902
                     /gene="rsfS"
                     /locus_tag="VXE36_000285"
     CDS             29549..29902
                     /gene="rsfS"
                     /locus_tag="VXE36_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0778653.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            30005..30751
                     /locus_tag="VXE36_000286"
     CDS             30005..30751
                     /locus_tag="VXE36_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0778654.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30761..31858
                     /locus_tag="VXE36_000287"
     CDS             30761..31858
                     /locus_tag="VXE36_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0778655.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
     gene            32096..32350
                     /locus_tag="VXE36_000288"
     CDS             32096..32350
                     /locus_tag="VXE36_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV0778656.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSIQVHVIEE"
     gene            32354..32608
                     /locus_tag="VXE36_000289"
     CDS             32354..32608
                     /locus_tag="VXE36_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV0778657.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            32799..34412
                     /locus_tag="VXE36_000290"
     CDS             32799..34412
                     /locus_tag="VXE36_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0778658.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RNESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            34542..35168
                     /gene="gmk"
                     /locus_tag="VXE36_000291"
     CDS             34542..35168
                     /gene="gmk"
                     /locus_tag="VXE36_000291"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0778659.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            35193..35507
                     /locus_tag="VXE36_000292"
     CDS             35193..35507
                     /locus_tag="VXE36_000292"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0778660.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            35573..37969
                     /locus_tag="VXE36_000293"
     CDS             35573..37969
                     /locus_tag="VXE36_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0778661.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGKADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            37982..38917
                     /locus_tag="VXE36_000294"
     CDS             37982..38917
                     /locus_tag="VXE36_000294"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0778662.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            38910..40223
                     /gene="rsmB"
                     /locus_tag="VXE36_000295"
     CDS             38910..40223
                     /gene="rsmB"
                     /locus_tag="VXE36_000295"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0778663.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            40238..40978
                     /locus_tag="VXE36_000296"
     CDS             40238..40978
                     /locus_tag="VXE36_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0778664.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            40975..42954
                     /gene="pknB"
                     /locus_tag="VXE36_000297"
     CDS             40975..42954
                     /gene="pknB"
                     /locus_tag="VXE36_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0778665.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            43069..43827
                     /locus_tag="VXE36_000298"
     CDS             43069..43827
                     /locus_tag="VXE36_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0778666.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            43829..44278
                     /locus_tag="VXE36_000299"
     CDS             43829..44278
                     /locus_tag="VXE36_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0778667.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            44340..44966
                     /locus_tag="VXE36_000300"
                     /pseudo
     CDS             44340..44966
                     /locus_tag="VXE36_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            45034..45282
                     /locus_tag="VXE36_000301"
     CDS             45034..45282
                     /locus_tag="VXE36_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778668.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            45413..46585
                     /locus_tag="VXE36_000302"
     CDS             45413..46585
                     /locus_tag="VXE36_000302"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0778669.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            46585..47859
                     /locus_tag="VXE36_000303"
     CDS             46585..47859
                     /locus_tag="VXE36_000303"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0778670.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(47894..48859)
                     /locus_tag="VXE36_000304"
     CDS             complement(47894..48859)
                     /locus_tag="VXE36_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0778671.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(48840..50294)
                     /locus_tag="VXE36_000305"
     CDS             complement(48840..50294)
                     /locus_tag="VXE36_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0778672.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            50347..50544
                     /locus_tag="VXE36_000306"
     CDS             50347..50544
                     /locus_tag="VXE36_000306"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778673.1"
                     /translation="MQAFYVKKEEKLSNDYHKINTGNQSNFYENVKDNEIKDFLIKVS
                     NLFFKESLMKQSKTINLKLAR"
     gene            50671..52554
                     /locus_tag="VXE36_000307"
     CDS             50671..52554
                     /locus_tag="VXE36_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0778674.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGFDDTTMVIVTNTADYASVAPVATGSVAKGNAVIE
                     VKI"
     gene            52703..53590
                     /locus_tag="VXE36_000308"
     CDS             52703..53590
                     /locus_tag="VXE36_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0778675.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(53910..54527)
                     /locus_tag="VXE36_000309"
     CDS             complement(53910..54527)
                     /locus_tag="VXE36_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0778676.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(54942..55130)
                     /locus_tag="VXE36_000310"
                     /pseudo
     CDS             complement(54942..55130)
                     /locus_tag="VXE36_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(55640..55720)
                     /locus_tag="VXE36_000311"
                     /pseudo
     CDS             complement(55640..55720)
                     /locus_tag="VXE36_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            55837..56730
                     /locus_tag="VXE36_000312"
     CDS             55837..56730
                     /locus_tag="VXE36_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778677.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            56727..57926
                     /locus_tag="VXE36_000313"
     CDS             56727..57926
                     /locus_tag="VXE36_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778678.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFLLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(58279..59046)
                     /locus_tag="VXE36_000314"
     CDS             complement(58279..59046)
                     /locus_tag="VXE36_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778679.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(59063..59758)
                     /locus_tag="VXE36_000315"
     CDS             complement(59063..59758)
                     /locus_tag="VXE36_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778680.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(59763..60128)
                     /locus_tag="VXE36_000316"
     CDS             complement(59763..60128)
                     /locus_tag="VXE36_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0778681.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            60268..60741
                     /gene="nrdR"
                     /locus_tag="VXE36_000317"
     CDS             60268..60741
                     /gene="nrdR"
                     /locus_tag="VXE36_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0778682.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            60742..61911
                     /locus_tag="VXE36_000318"
     CDS             60742..61911
                     /locus_tag="VXE36_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0778683.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSPKETTIIKEAKSKTALQFLAEIKQTRKGTTTQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            61912..62808
                     /gene="dnaI"
                     /locus_tag="VXE36_000319"
     CDS             61912..62808
                     /gene="dnaI"
                     /locus_tag="VXE36_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0778684.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            62805..63518
                     /locus_tag="VXE36_000320"
     CDS             62805..63518
                     /locus_tag="VXE36_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0778685.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            63532..64842
                     /gene="der"
                     /locus_tag="VXE36_000321"
     CDS             63532..64842
                     /gene="der"
                     /locus_tag="VXE36_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0778686.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            64930..65265
                     /locus_tag="VXE36_000322"
     CDS             64930..65265
                     /locus_tag="VXE36_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778687.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            65405..65755
                     /locus_tag="VXE36_000323"
     CDS             65405..65755
                     /locus_tag="VXE36_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778688.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(65977..66828)
                     /locus_tag="VXE36_000324"
     CDS             complement(65977..66828)
                     /locus_tag="VXE36_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0778689.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSSL"
     gene            67155..67547
                     /locus_tag="VXE36_000325"
     CDS             67155..67547
                     /locus_tag="VXE36_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778690.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            67569..68360
                     /locus_tag="VXE36_000326"
     CDS             67569..68360
                     /locus_tag="VXE36_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778691.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            68353..68994
                     /locus_tag="VXE36_000327"
     CDS             68353..68994
                     /locus_tag="VXE36_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778692.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            68998..69630
                     /locus_tag="VXE36_000328"
     CDS             68998..69630
                     /locus_tag="VXE36_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0778693.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            69658..69945
                     /locus_tag="VXE36_000329"
     CDS             69658..69945
                     /locus_tag="VXE36_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778694.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            70091..72604
                     /gene="secA"
                     /locus_tag="VXE36_000330"
     CDS             70091..72604
                     /gene="secA"
                     /locus_tag="VXE36_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0778695.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            72685..73716
                     /locus_tag="VXE36_000331"
     CDS             72685..73716
                     /locus_tag="VXE36_000331"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0778696.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            73718..74749
                     /locus_tag="VXE36_000332"
     CDS             73718..74749
                     /locus_tag="VXE36_000332"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0778697.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            74788..75156
                     /locus_tag="VXE36_000333"
     CDS             74788..75156
                     /locus_tag="VXE36_000333"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0778698.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            75146..76249
                     /locus_tag="VXE36_000334"
     CDS             75146..76249
                     /locus_tag="VXE36_000334"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0778699.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            76268..78283
                     /gene="recG"
                     /locus_tag="VXE36_000335"
     CDS             76268..78283
                     /gene="recG"
                     /locus_tag="VXE36_000335"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0778700.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            78600..79580
                     /locus_tag="VXE36_000336"
     CDS             78600..79580
                     /locus_tag="VXE36_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0778701.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        24159 a        14360 c        17813 g        23628 t
ORIGIN      
        1 atatttttaa tgaagatatc cccaaagagt ggttttattt gatggagaag agattagaaa
       61 aacttaactg tgaaattttg aatatagaaa ttgatgcaga aaaagtaaag tatttttcta
      121 ctcctgatga acacatcaag tatatgactt attttcgcta ttttattgca gaatttgtaa
      181 aagaagatag ggccgtgtat ttagactgtg atatggttat tcatgggaat ataaatccat
      241 tatttcagaa agatttcgaa ggaaattata taatcgccgt tccagatggg tggtataaaa
      301 atatttttaa tgcaggaatg atgatggtaa atgttcataa gtggaaaact gataatattt
      361 gtcaaaatct tttagagttg actgcagaaa aacatcaaga aatctatggt gaccagggag
      421 tcttaaatct attgtttgaa aataagtgga agaaagtatc tcctcattat aattttatgg
      481 ttggacttga tacattgggt tattgggctc aaaagccaga gtggttttta aatagttggg
      541 atgaaaacta taaacctgct attattcatt ttgaaggtaa agataaaccg tggaatgatt
      601 cattaaaaac aagatataga gaattgtggt ggttttataa tggtttggat tggcaaacta
      661 ttttgtcgca agttgataac aaaccaacta cgtttagtga aattgcaaca gttagtttat
      721 ttcatacagc gatctttaca gatacgcacg agttggaaca tatagaatat ctagtagaaa
      781 aacttccgaa tgtccatttt catatttttg ctcacagtta ttttggaccg agagtacaag
      841 cgttgaacca ttttttaaat gtatctcttt atcccaatta tacaccgtat caatctcaag
      901 aagtgctgag taagttagat ttttatttag atatcaatca taatcatgaa atagataata
      961 ttatttcaaa agttcataac ctatcgaaac cgatatttgc ttttgagaat acgagtcatg
     1021 atacaaataa tcgaagtcag atattgcctt caacggagcc aaaggaaatg gtagaggcta
     1081 ttagacaatt cataggagaa taagtttatg gcagacgaat taattagtat tatagtccca
     1141 atctacaacg ttgaaaaata tttgcgacag tgtttagata gcattcagaa tcagacgtat
     1201 caaaattttg agtgtttatt aatcaatgat ggctctccag atcattcatc caaaatatgt
     1261 gaagaatttg tagagaaaga ttctcgtttc aaatattttg agaaagcaaa cggcggtctt
     1321 tcatcagctc gtaacctagg tattgaatgt tcgggggggg cgtacattgc ttttgtagac
     1381 tctgatgatt ggttggaatc ggactattta gaagtactat attcaaaaat agtagagtat
     1441 gatacggatt ttgtgatagg atcatataaa aagtttagta tgtctgataa ttgttattat
     1501 atgcatgttt gggaacagga ttattatgaa aaaatctgga ctagtcagga attgataact
     1561 gtgcttccaa atattgaaaa ttatgatagt tcttacacag tttcttgggg taaactattt
     1621 aaacgttttt tatttgacga ggtattattt aacgagcaac gtagatttgg tgaggatttt
     1681 gagtgtagtt ttaaattgta tttaactatg actagctgct tatatattca tagagaactt
     1741 tataattata gagtacactc agaatcgatg gtgggaaaag ttaggacaga gagacaacta
     1801 atggatgatg tggaaatccg acttggacga attccttttt tgattggaag aggaattgat
     1861 tcgactcctt acatagcaga aattaagaga cttattcaat ggcgtttaga tacgaaatca
     1921 gatgtcgaag aaggtgagtc aaacgctttg tgtatgtatc gagaaatact taggaattta
     1981 taggggacga aatgaaaaaa gcaattgttt taggagcaga taaccattac atggataaag
     2041 tggaaacaac cataaaatct atctgttcta agaataaaga agtgaaattt tatgttttta
     2101 acagtgacct tcccacagaa tggtttcaat tgatggataa aaggttgtct gttttgggtt
     2161 cggagattgt gaatgtgaag gtgacagaga gtctaataaa tcaatttcat cttcccaccc
     2221 ctcatcttag ttctgctacc tatcttagat attttatccc aactattgtt tttgaaaaaa
     2281 gagttcttta tttggatagt gatataatag tgaccgcaga tttaacctca ctttttgaat
     2341 ttcctttaga tggctgtcct cttgcagccg ttccggatat tccaaacacg tctgaaggat
     2401 ttaattctgg agttttactt attgatacgg ataggtggag agaagatgat attcaaaatc
     2461 aattattaaa tttaacaatt aagcatcatg aacatgtata tggcgatcaa gaaattctaa
     2521 atatgttgtt caaagataga tggaagaaat tgagtttatc ctacaattta caggttgggt
     2581 atgataccta ccgacattcg ttaggagata atgaatggta tcatttgttt gaaggaattc
     2641 ccaatattat tcactataca acacagaata aaccttggag tcactatcga ttcaaccgtt
     2701 ttcgtgatat ttggtggttc tactacggat taaactggaa tgatattttg ttagataatc
     2761 aaatacttca agaaaatttt gagaagttaa tcaaaccgat tacatgtcat gccagtattt
     2821 ttacaaacac aggtgatata gaagggctac cttatcttct ggaacagtta ccgaatgttc
     2881 aattccacat tgctgcacca acttattttt ctccgaatat tgtggaatta cagagatatt
     2941 caaatcttta tatatatccc tgtgttgacc ccaaaatgaa agaaacacta atcaatcaaa
     3001 ctaattttta tttggatatt aattatggac cagctttgga cgatgcctta caagagattg
     3061 tacgacaagg gaacccaatc tattcgtttg aaagtgcgtc ccatttttct aatggagaga
     3121 atcaagtatt tgcagtagat aatgttgatg aaatggtaaa aagcatccaa aataaactaa
     3181 gtgagtccca tcgttagttg tcaaaaaata tgatgattag aatgagatag cgtaatatga
     3241 aattacattt aacaaattta tacggcatgg ctggtgatag tacggttatc ttagctcaaa
     3301 atgctgttca aaagatagct agtcaactgg gatttagaga ggttggtatt tatttttaca
     3361 acattgcttc agatagtcct tctgaaatga ataagcgtct ggatggtatt atggccagta
     3421 tctctattgg tgatatctta gtctttcagt ctccaacctg gaatggcttt gaatttgatc
     3481 gtctcttgtt tgataagcta aaggatatgc aggtgaaaat tatttgcttt atccatgatg
     3541 ttgttcccct catgtttgat agtaactatt atctcatgaa agactatatg tacatgtata
     3601 atctatcaga tgttttgata gtgccgtcag agagaatgaa aacacgcctg atggaagaag
     3661 gattgacgac taagaagatt cttgttcaag gtatgtggga tcatcctcat gatttatcct
     3721 tatacacccc tgcttttaaa aaagaacttt tttttgctgg aagtttagag cgttttccag
     3781 acttacaaaa ttggtctcaa gatacgcctt tgagagtatt ttcaaataaa ggggaagcta
     3841 gttctagtgc tagaagtctc agcatcgaag gatggaaaaa agatgaggaa ttgttgctag
     3901 aattatcaaa gggtggattt ggccttgtct ggggaaccca tcaaaatgag ggagaaagta
     3961 accaatacta taccttgaat atatctcata aggtgagtac ctatctaaca gctggtatcc
     4021 cagtcattgt accaagtagc ttgtcaactg ctaaatttat agtagatcaa ggcttaggct
     4081 ttgtggcgaa tagtctagaa gaagttcatg cgatagttga taaaatgaat ctacaagaat
     4141 atcaagaaat gacgaatcgg ataaaaacct ttagttattt gctaaaagaa ggttatttta
     4201 ctaaaaaatt attggtagat gcaatttacc atttgggagt tgaataagag aacaagatga
     4261 ttaaaacaat tgtattagct ggtgatcgta attacatcag gcagttagaa acaatcataa
     4321 aatctatttt ataccacaat cgagatgtta agatttatat tttaaatcaa gatattatgc
     4381 cagattggtt tcgcaaacca cgaaaaatag ctcgcatgtt agggagtgag attatcgatg
     4441 ttaaactacc tgaacaaact gtgtttcaag attgggaaaa gcaagatcac attagtagca
     4501 ttacctatgc tagatatttt attgcagatt atatccaaga agataaggtt ttatatttag
     4561 acagtgattt gattgtaaat acttctttag agaaattatt tagtatttgt ttagaagaaa
     4621 aatcactcgc agcagttaaa gatacagatg gaattacatt taatacaggt gttctattaa
     4681 tcaacaataa aaaatggcgt caagagaaat taaaagaacg actaattgaa cagagcattg
     4741 ttacaatgaa ggaagttgaa gaaggccgtt tcgagcattt taatggtgat caaacgattt
     4801 ttaatcaggt cttacaagat gattggttag agctggataa agaatttaac cttcaagtgg
     4861 gtcatgatgt aactgctttt tataataaat gggaaaatta ttttaatgaa ttagtacccc
     4921 ctagtatcat acattttgtg tcttatagaa aaccttggac taccttgaca gccaatcgtt
     4981 atcgtgattt atggtgggaa ttccatgatt tggagtggag tcagatttta caacaccata
     5041 tgggagaatt tgaactaata tcgcctctag ataaggaatt ttcttgctta accttaacga
     5101 attcccaaga tttagaagga atagaagagc tagttacagc tctacctgag gtggtatttc
     5161 atatcgcagc ttggacggat atgggagata aattaaaaaa attagctgta tataataatg
     5221 tgagattgca tccacaaatt gttcctcctg tattagataa gctgaaaaag tcaacaaatc
     5281 tatatttgga tatcaatcat ggtagtgcag atgagaactt tttaaaatct ttgcaagaac
     5341 aagaaaaaac gctactagct tttcaatcga ctcagcacgg agagttagga caaatcgttt
     5401 tcgaaaatgg gaaagtttcc tttatgattg atacgattaa agattttaag aaaaacggac
     5461 atcttacctg ttttcgacaa cttccaagtt taacttgttt aacgtttacg gcttctcagg
     5521 atatcgaaca attggattac ttggctggac agttgccaaa tgttgttttt caagttgctg
     5581 cttggacagc tatggggcca aaattatatg atttgtctaa tcgttatcct aatattcagc
     5641 tctatccggc aatttctaga gataagctag acgagttgaa ggagaagatg gatgcttatt
     5701 tagatatcaa cctactgact tcaacatccg atatcgttgc agaaatggct catctatcta
     5761 aacctatact agccttttat aaatctcaaa atgggaataa tggccaaagg ttgtattcaa
     5821 gtgaacatcc tgaacgaatg ttggctgatt tgcaaaaatt gataactaag gatatgctag
     5881 aaaaaccgct tgatataatc caggtgaaag ggatagatga aaccttggat tatgttattg
     5941 aacacaactc ttctttagtt cgttttggag atggggaaat caatatgctt gcagggcatt
     6001 caattcccta ccaggattat gatgaagagt tggtttcaat catgagggac attatcggcc
     6061 aagaaagtcg agaagattta gtagtgtgcc ttcctgatgc ttttacagat cgttttaggt
     6121 ttacatcgtg ggcgattcca ttttggaaag atcacatgga tcattatatg gatttttaca
     6181 gagagttatg cagtgattca tggtatggct caacctttgt atctcgccct tatatcgatt
     6241 ttgaagacaa gagtcaagct aaagctcaat ttgaaaaatt gaaaagcatt tgggaaaacc
     6301 gtgacttact gatagtcgaa ggtgcgactt ctcgttcagg tgtcggaaat gatttattcg
     6361 atgaggcaaa ttctattaag cgaattatct gtccttctca tagtgccttt tctagagttc
     6421 atgaaattga acaagaaatt gaaaagtatg ctggtggtcg cttgatttta tgtatgcttg
     6481 gacctacagc aaaagtttta gcctatcatt taagtcgaaa gggttaccaa gtcttagata
     6541 ttgggcatat tgactccgag tatgagtgga tgaagatggg tgctaaaact aaggttaaat
     6601 tttcacataa acatacagca gagtataatt ttgatcaaga tattgagttc attgaggatg
     6661 aaacctataa tagtcagatt ttagttgatt tatcaaagag agaagtatga aagatttaat
     6721 aagtgttata gtaccagttt ataacgtaga accatttatt gctagttgcc tagacagttt
     6781 atcgaaacag aactatcaaa attttgaagt tttattagta aatgatggtt ctacagataa
     6841 ttcaggagtg atttgtcgag aatattctga tcgtgacagt cgtttccact attttgaaaa
     6901 agagaatggg ggactttcgg atgcacgtaa ttttggaatc gagagatcta aaggagatta
     6961 tattacattt gtagactcag atgattgggt tactgaagag tatttatcaa ttcttataga
     7021 aactttgaag gagcagcatt ctgaaattgt tgtttcaact tattcaacct ataatgagtc
     7081 agatggttta ttctatattc acgtatttga cttcgattat tatgtgaaaa attataattc
     7141 aaaacttcta atggaagaac ttcctttatt agaggggtat gatatgagct ttttaacttc
     7201 ttggggaatt ctatttaaaa gggaattatt tcaagaagtt cagtttccgt ttggtcgggt
     7261 gtgtgaggat agaggatata ggaaccaatt ataaactatt tatgcaggtt gagaaagtaa
     7321 cctatattaa taaagttttg tattggtata gggttgggaa agaaggactt tctaattctt
     7381 attcaccgaa gatgatgcgt gatgattgtg attttaggtt agaacgaatt gccgtgctag
     7441 cgctaaaagg atatgatgtc agtaaatatt tagaccagat gaatttctat ttgaaatatc
     7501 gtcatgatat tgcaattcaa cgagaactta aggagaatgt ggaaacaaga catttagaaa
     7561 tgttagacta tttattgaat ggtaataaat ataactgaaa attaagatag agagacgata
     7621 aaatgttaca agataagaaa tctgtagtat ttgcaggtga ttacgcttat attcgacaaa
     7681 tcgaaacggc gatgaagtca ctctgtagac acaatagtca tttgaaaatt tatctgctaa
     7741 atcaggacat tcctcaggaa tggtttagtc aaataagaat atatttacaa gagatggggg
     7801 gcgacttgat tgactgcaag ttaattggct cacagtttca aatgaattgg tctaataaat
     7861 tacctcatat caatcatatg acatttgcac gctattttat tccagatttt gtaacagaag
     7921 ataaagttct ctatctagat agtgatttga ttgtgactgg tgatttgacc gatttgtttg
     7981 aattagactt aggtgaaaat tatttggcag cagctcgttc ttgctttgga gcaggagtcg
     8041 gcttcaatgc tggtgttctc ttgattaaca acaaaaaatg gggatctgaa actattcgac
     8101 aaaaattgat tgacttaaca gaaaaagaac atgagaatgt ggaagaagga gaccagtcaa
     8161 ttttgaatat gttgtttaaa gatcaatata gttcccttga agatcaatat aattttcaaa
     8221 taggatatga ttatggggcg gcagccttta aacatcaatt catttttgat attccgctcg
     8281 aaccactgcc actaatttta cactatattt ctcaggataa gccttggaat caattttctg
     8341 ttggacgtct aagagaagtt tggtgggaat actctttgat ggattggtct gttattttaa
     8401 atgaatggtt ttcaaagagt gtgaagtatc ctagtaaatc acaaatattt aagttgcaat
     8461 gtgttaattt aacgaattct tggtgtgtcg agaaaatcga ttatttggcg gagcaattgc
     8521 cagaagttca ttttcatatt gttgcttata caaatatggc aaatgaacta ctagctttaa
     8581 cgcgttttcc taatgttacc gtatatccaa attccttacc aatgttattg gaacaaatag
     8641 taatagcttc agatttgtat ttggatttga atcatgatcg aaaattagaa gatgcatatg
     8701 agtttgtgct taagtacaaa aaaccaatga tagctttcga caatacttgc tctgaaaatc
     8761 tttctgagat ttcatatgaa ggtatctatc caagctccat tccgaaaaaa atggttgcag
     8821 caatcagatc ttacatgagg tagagaacag tatgagaaaa tcaatagtat tagcggcaga
     8881 taatgcctat cttattcctt tagagacgac tataaagtct gtattgtatc acaatagaga
     8941 tgttgatttt tatattctca acagtgatat agctcctgaa tggtttaaat tattggggag
     9001 aaaaatggaa gttgtgaatt ctacaattcg cagtgtacac attgataaag aactttttga
     9061 aagctataaa acaggacctc atataaatta tgcttcttac tttagatttt ttgcgacaga
     9121 agtggttgaa tctgataggg tattgtatct ggattccgat atcattgtaa ctggggaact
     9181 agctactttg tttgagatag atctcaaagg atattcaatt ggtgctgttg atgatgtcta
     9241 tgcctatgaa ggacgaaaat ctggatttaa ttctggagtt ttattaatgg atgttgcaaa
     9301 gtggaaagaa cattctattg tcaatagttt attggaatta gcggccgagc agaatcaagt
     9361 tgttcatctt ggggatcaga gtattttaaa tatttatttt gaggataatt ggctagcctt
     9421 agataaaaca tataattata tggtgggtgt tgatatttat caccttgctc aagaatgtga
     9481 acgtctagat gacaatccac ctacaattgt tcactatgct agtcatgata aaccttggaa
     9541 tacatatagt atatctagac tacgtgaatt atggtgggtt tatagagatt tggattggtc
     9601 agagattgct tttcaacgtt ccgatttaaa ttattttgaa agaagcaatc agtctaaaaa
     9661 acaagtgatg cttgtgacat ggagtgcaga tataaaacat ttagagtatt tagtacaacg
     9721 gttacctgat tggcattttc atttggctgc accgtgtgat tgttctgagg agctgacctc
     9781 tctatcacag tatacgaatg taacagtata tcaaaatgta ttacatagta gaattgattg
     9841 gctattggac gattctatag tttatttaga tattaataca ggtggagagg tttttaatgt
     9901 agttacaagg gcacaagaaa gtggcaagaa aatcttcgct tttgatatca cacgtaaaag
     9961 tatggatgat ggactctatg acggtatttt ttctgtggag agaccagatg atttagtgga
    10021 tagaatgaag aatatagaga tagagtaatg agtgaattaa ttagtgttgt ggtaccgata
    10081 tacaatacgg gaaaatattt agtggagtgt gtcgagcata ttctgaagca aacctatcaa
    10141 aatatagaaa ttattttagt tgatgacggt tctacggata attctgggga aatttgtgat
    10201 gcttttatga tgcaagataa tcgtgtgcga gtattgcatc aagaaaataa ggggggggca
    10261 gcacaagcta aaaatatggg gattagtgta gctaagggag agtacatcac gattgttgat
    10321 tcagatgata tcgtaaaaga aaatatgatt gaaactcttt atcagcaagt ccaagaaaag
    10381 gatgcagatg ttgttatagg gaattactat aattatgacg aaagtgacgg gaatttttat
    10441 ttttatgtaa cagggcaaga tttttgcgtc gaagaattag ctatacaaga aattatgaac
    10501 cgtcaagcag gagattggaa attcaatagc tcggccttta tattgccgac atttaagttg
    10561 attaaaaaag aattattcaa tgaagttcac ttttcaaatg gtcgccgctt tgatgatgaa
    10621 gcaactatgc atcgctttta tcttttagcc tctaaaatcg tctttataaa cgataatctc
    10681 tatctgtata gaagacgttc aggaagcatc atgagaacgg aatttgatct ttcctgggca
    10741 agagatattg ttgaagtgtt ttctaagaaa atatcggatt gtatcttggc tggtttggat
    10801 gtctccgttc tgcgtattcg atttgtcaat cttttaaaag attataagca aactttagaa
    10861 taccatcaat taacagatac tgaggaatat aaagatattt gtttcagatt aaagttgttt
    10921 tttgatgcag aacaaagaaa tggtaaaagt tgaaataaaa gaattgttat ttaccatatc
    10981 acaaacaatg aaggtgaggg gagtgtttta tgactaagat ttattcgtca atagcagtaa
    11041 aaaaaggact atttacctta tttctactgt ttatctatgt attgggaagt cgtattactc
    11101 tcccttttgt tgacctaaat actaaagatt ttttaggagg ttcaacagcc tatctagcct
    11161 tctcagccgc cctaacaggt ggaaatctaa gaagtttgtc aattttttct gttggattat
    11221 ccccttggat gtcagctatg attttgtggc agatgttttc atattctaaa aaattggggc
    11281 taagttctac agcgattgaa attcaagatc gtcgaaaaat gtatctgacc ttgctaattg
    11341 ctgtgattca atccttggca gttagcttga gcttgccagt acaatcctcc tattctgcaa
    11401 tattggttgt tctaatgaat acaatattgc tgatagcagg aacatttttt cttgtttggt
    11461 tgtcagattt aaatgcgagc atgggaattg ggggttctat agtcattctc ctatccagca
    11521 ttgttttaaa tatccctcag gatgttattg aaacttttaa actggtttat atccctacag
    11581 ggattgttgt cttgcttgtt tttatgacca ttatattttc ttacttgctt gcccttatgt
    11641 atcgagctcg ctatttggtt cctgttaata aaattggctt acacaatcga tttaaacgct
    11701 attcttatct cgaaatcatg ttgaatcctg caggtgggat gccttatatg tatgtgatga
    11761 gttttcttag tgtaccagct tatttgttca tcttgttggg atttattttc cctaatcatt
    11821 cagggctagc ggctttatca aaggaattta tggttgggaa gcctttgtgg gtctatgttt
    11881 atatttcggt cttattttta tttagtatca tttttgcttt tgttacgatg aatggagaag
    11941 agattgcaga ccgtatgaaa aaatctggag aatacattta tggtatttat ccaggtgcgg
    12001 atactagtcg atttattaat cgattggtcc ttcgtttctc agtcataggt ggtctcttta
    12061 atgtgattat ggcaggtggt cccatgcttt ttgttttgtt tgatgaaaag ttattacgat
    12121 tggcaatgat tccaggctta tttatgatgt tcgggggcat gatttttacg attagagacg
    12181 aggtcaaggc tttaaggcta aatgagacct atagaccttt gatttaggag acttttatgt
    12241 attattttat tccagcttgg tatgggtcag aaagaacatg gcatgcagat atcactccat
    12301 ggtatttttc tcattttcgt ctagagtttg atgatacctt tcaccagatc cggctctttc
    12361 aagagcaaga tatagattct cgtctattag tattagctta ccagcctcat ctacgttatt
    12421 ttttatatag acatggtgtg ttagaaacgg atacttattc cgtttttgat gttatgcaag
    12481 attttcataa tctccatacc caagttttaa gcattagaga tattgagtgg gatgatgact
    12541 gtgaatttat ttatagtccc tttacgatta tcgttcaaaa aaatgggaag aaatttgcta
    12601 aggttgaaca tggagttgaa ggtttcatca gtgatataca gtattttgga ccgaatggtc
    12661 aaatacatat gcaccatatc atggatgatc gagggtttat atcgagtatt attttttttg
    12721 aagatgggca agcagcctat caagaatatt tgaatcctaa gggagtttgg caatttagag
    12781 agcgtttaaa agaaggagga caggtagaag tcaatccaat tttgggttat cgctttaaaa
    12841 tgcttaccta tcaaaatatg ggagatctgg tggcagaatt ttttgagaat tatctgcaaa
    12901 cgtatgtgaa ggatcaggat atttttatgc ttccttctca ttctcatcat gaccagttgg
    12961 tactagatcg tttacctagt actaatccta aactgttgag tctgttcatt ggacgtaatc
    13021 ctcaagatac ctttagggat ttagatgtaa cttttgaaaa atcggatttg attttggtgg
    13081 atagagagga tagtttacga ttgttgcagg agttgtatcc tgaacgaatg catcaatgtt
    13141 atcatttatc atcttttgac acccgattac gattgggacg aagccaaact aagaaagaat
    13201 ccatcattta ttttcaactg gattttgagc aggggattga taatcaagct ctgcttcaag
    13261 tcttgtcctt tgtcgctgaa aataaggata ctgaggtgat ttttggagcc tttgctgcta
    13321 gtcaggagca aatgaatgag gttgaaggga ttgttgagtc tttcatccaa gaaaacattc
    13381 aatccgaaaa tctgggaaag gcgattgatt atggtgatgc agaaaatcct ctggaagaaa
    13441 atcaacacca ggacttacgc ttacagtttg ttaacttgaa tgatgagtta gatttgataa
    13501 aaacactaga atttgtccgt ttgattgtgg atttaaatag acatcctcat ctctacacac
    13561 agattgctgg gattagtgca ggaattcctc aaatcaacct agttgaaacc gtctatgttg
    13621 aacatttaaa aaatggttat ttgttagcag atgttacaga attttctaag gctgcacatt
    13681 attacacaga taggttgaag gagtggaatg agtccttgat atattcaatt gataagatta
    13741 aggagcacac aggacaacaa tttcttggaa aattagagaa atggatagag gaggttaaaa
    13801 atgtcaaagg aacttaatat tttacagata ggacttgcca attgggaaaa tcactatgac
    13861 atacctgaaa atatgaattg gtatcatttt tacccaaact catcagaagc tcttcgtgaa
    13921 ataatcgaaa aagaggatat taaccgtttt catgcagttt taatagaaga tggtcagtat
    13981 tccagagact tattttccta tgtaaaatat tttgaacctt atactttatt ctataaccag
    14041 aatctacaaa taaatgatag agaggttgtg gattttctaa aaaaacgatg tgcacaagca
    14101 attgattttt taagtcccca acaactaatc aatgatttaa gtaaatctct ttttggcggt
    14161 gggtatggtg ataaactctt tcctccgacg atacaagtca atccaaattt tacaggagct
    14221 atttcttatc aaggattgga ttatgtcagt ttggaaggtg agtttgggca agattttgcc
    14281 cagcttgcct attgggctta taatattatg gtgcaaaaaa cactccctat tgagttgtgg
    14341 cttgaatatg agaaggaagg caattgtgac tttcgtttag taatccgtaa aatgtggagt
    14401 gggtctgttg atgatttctt tgaagaagta atagtatctg aaaaagactt ggagcaagca
    14461 ctttttatgg atagtcgaga cggagactac tttctctcga tatctgttga agcaagaggt
    14521 cgtggaacta tcaaactagg taatcttcac caacgatgga gtcgaaaaca atttggtaag
    14581 tttgtacttg gtggaaatat cctacatgat tccaagcgtg atgaaataaa ctatttcttc
    14641 catccaggtg attttaaacc gcctttgact gtctattttg caggttatcg acctgcagaa
    14701 ggattcgagg gttactttat gatgaaaact cttggatgtc ccttcatttt attttctgat
    14761 ccacgtttag aggggggagc tttttatctc ggaacggatg agctagaggg aaaagtaaag
    14821 gatacgatca ctcactatct tgattattta ggctttgatc ataaggattt gattttatca
    14881 ggtctttcta tgggaacgtt tccggctctc tattatggtg cttcttttga accccatgcc
    14941 atcatagttg gtaagccctt ggctaattta ggaactatag ctagtcgtgg acgtttggac
    15001 gcaccgggtg tctctaactt agcttttgat tgtttaattc atcatacagg tgggacaagt
    15061 tctcaagata tgacggagtt ggatcagcgt ttttggaaaa tttttaaaca agcaaatttt
    15121 tcaaagacaa cctttggttt atcctatatg aaagatgaag aaatggatcc acaagcctat
    15181 gaacaattag tgtcttatct gtgtaataca ggtgcgaaga ttttatctaa aggaactgct
    15241 ggacgacaca atgatgatac agataccaat atttcttggt ttttgcactt ttatagaatg
    15301 gtcttagaga ctggttttgg aagggagaaa agatgattat tacacagaga cagtctattc
    15361 attggggaga agtgggtggg acttatatgt atggaacaac tgtatcttat taccctgaca
    15421 aaagtgttcg tctgtataat cctctattgc catctggtga gattctaaag acttggtttt
    15481 ctagtgtcaa ttaccaggct gcacgaaccc aacctcagct tcccttatta aaaagaaagc
    15541 aggagtatca actatcactg gtttttgatt gtcagcctga aaatggagtt tataccaaga
    15601 taactttttt tgaccgctat ggtgatattt tagaaaaaaa ggtagaaaaa gtgaaagatt
    15661 tcatatttac ttatccagaa gatagttata cttatcaagt ttctctttta agtgctggat
    15721 ttgagtcctt aactttctat catttttcta ttaaggagat cagaagtgtt tagacgttta
    15781 ggtcaagatt tccagcttag gaaagtgaaa aagattttaa agcagattaa tgccctgaaa
    15841 ggcaagatgt cctctctttc ggatcaagaa ttagtagcta aaacagtaga gtttcgtcag
    15901 cgtctttccg agggagaaag tctagacgat attttggttg aagcttttgc tgtggtgcgt
    15961 gaagcagata agcggatttt agggatgttc ccctatgatg ttcaagtcat gggagctatt
    16021 gtcatgcact atggaaatgt tgctgagatg aatacggggg aaggtaagac cttgacagct
    16081 accatgcctg tctatttgaa cgctttttca ggagaaggag tgatggttgt gactcctaat
    16141 gagtatttat caaagcgtga tgccgaggaa atgggtcaag tttatcgttt tctaggattg
    16201 accattggtg taccatttac ggaagatcca aagaaggaaa tgaaagctga agaaaagaag
    16261 cttatctatg cttcggatat catctacaca accaatagta atttaggttt tgattatcta
    16321 aatgataacc tagcctcgaa tgaagaaggt aagtttttac gaccgtttaa ctatgtgatt
    16381 attgatgaaa ttgatgatat cttgcttgat agtgcacaaa ctcctctgat tattgcgggt
    16441 tctcctcgtg ttcagtctaa ttactatgcg atcattgata cacttgtaac aaccttggtc
    16501 gaaggagagg attatatctt taaagaggag aaagaggagg tttggctcac tactaagggg
    16561 gccaagtctg ctgagaattt cctagggatt gataatttat acaaggaaga gcatgcgtct
    16621 tttgctcgtc atttggttta tgcgattcga gctcataagc tctttactaa agataaggac
    16681 tatatcattc gtggaaatga gatggtactg gttgataagg gaacagggcg tctaatggaa
    16741 atgactaaac ttcaaggagg tctccatcag gctattgaag ccaaggaaca tgtcaaatta
    16801 tctcctgaga cgcgggctat ggcatcgatc acctatcaga gtctttttaa gatgtttaat
    16861 aagatatctg gtatgacagg gacaggtaag gtcgcggaaa aagagtttat tgaaacttac
    16921 aatatgtctg tagtacgcat tccaaccaat cgtccgagac aacggattga ctatccagat
    16981 aatctatata tcactttacc tgaaaaagtg tatgcatcct tggagtacat caaggaatac
    17041 catgctaagg gaaatccttt actcgttttt gtaggctcag ttgaaatgtc tcaactctat
    17101 tcgtctctct tgtttcgtga agggattgcc cataatgtcc taaatgctaa taatgcggcg
    17161 cgtgaggctc agattatctc cgagtcaggt cagatggggg ctgtgacagt ggctacctct
    17221 atggcaggac gtggtacgga tatcaagctt ggtaaaggag tcgcagagct tgggggcttg
    17281 attgttattg ggactgagcg gatggaaagt cagcggatcg acctacaaat tcgtggccgt
    17341 tctggtcgtc agggagatcc tggtatgagt aaattttttg tatccttaga ggatgatgtt
    17401 atcaagaaat ttggtccatc ttgggtgcat aaaaagtaca aagactatca ggttcaagat
    17461 atgactcaac cggaagtatt gaaaggtcgt aaataccgga aactagtcga aaaggctcaa
    17521 catgctagtg atagtgctgg ccgttcggca cgtcgtcaga ctctagaata tgctgaaagt
    17581 atgaatattc aacgggatat gatttacaag gagcgtaatc gtctaataga tggttctcgt
    17641 gacttagagg atgttgttgt ggatatcatt gagagatata cagaagaggt agcggctgat
    17701 cactatgcta gtcgtgaatt attgtttcac tttattgtga ccaatattag ttttcatgtt
    17761 aaagaggttc cagattatat agatgtaact gacaaaactg cagttcgtag ctttatgaag
    17821 caggtgattg ataaagaact ttctgaaaag aaagaattac ttaatcaaca tgacttatat
    17881 gaacagtttt tacgactttc actgcttaaa gccattgatg acaactgggt agagcaggta
    17941 gactatctac aacagctatc catggctatc ggtggtcaat ctgctagtca gaaaaatcca
    18001 atcgtagagt actatcaaga agcctacgcg ggctttgaag ctatgaaaga acaaatccgt
    18061 gcggatatgg tgcgtaatct cctgatgggg ctggttgagg tcactccaaa aggtgaaatc
    18121 gtgactcatt ttccataaga ggagaaaata tgacaattta caatataaat ttaggaattg
    18181 gttgggctag tagcggtgtt gaatacgctc aagcctatcg tgctggtgtt tttcggaaat
    18241 taaatctgtc ctctaagttt atctttacag atatgatttt agccgataat attcagcact
    18301 taacagccaa tattggtttt gatgataatc aggttatctg gctttataat catttcacag
    18361 atatcaaaat tgcacctact agcgtgacag tggatgatgt cttggcttac tttggtggtg
    18421 aagaaagtca cagagaaaaa aatggcaagg ttttacgtgt cttctttttt gaccaagata
    18481 agtttgtaac ctgttatttg gtggatgaga acaaggactt ggttcaacat gccgagtatg
    18541 tttttaaggg aaacctgatt cggaaggatt acttttctta tacgcgttat tgtagcgagt
    18601 attttgctcc caaggacaat gttgcagtct tataccaacg aactttttac aatgaagacg
    18661 ggactccagt ctatgatatt ttgatgaatc aagggaagga agaagtttat catttcaagg
    18721 ataagatttt ctatggaaag caagcttttg tgcgtgcctt tatgaaatct ttgaatttga
    18781 ataagtctga tttggtcatt ctcgataggg agacaggcat tggtcaggtt gtgtttgagg
    18841 aagcacagac agcacattta gcggtagttg ttcatgcgga gcattatagt gaaaatgcta
    18901 caaatgagga ctacatcctt tggaataact attatgacta tcagtttacc aatgcgaata
    18961 aggttgattt ctttatcgta tcaactgata gacagagaga agttctgcaa gagcaatttg
    19021 ccaaatacac cccgcatcaa ccaaagattg ttaccattcc tgtaggtagt attgattcct
    19081 tgacggagtc aagtcaaggg cgcaaaccat tttcattgat tacggcttca cgtcttgcca
    19141 aagaaaagca cattgattgg ttggttaagg ctgtgattga ggctcgtaag gaaatccctg
    19201 aattaacctt tgatatttat ggtagtggag gagaagattc tctgcttaga gaaattattg
    19261 caaatcatca ggcagaggac tatatccaac tcaaggggca tgcggaactt tcgcagattt
    19321 atagccagta tgaggtctac ttaacggctt ctaccagcga aggatttggt ctgaccttga
    19381 tggaagctat tggttcaggt ctacctctaa ttggttttga tgtgccttat ggtaatcaga
    19441 cctttataga ggatgggcaa aatggttatt tgattccaag ttcatctgac catgtagaag
    19501 accaaatcaa gcaagcttat gccgctaaga tttgtcaatt gtatcaagaa aatcgtttgg
    19561 aagctatgcg tgcctattct taccaaattg cagaaggctt cttgaccaaa gaaattttag
    19621 aaaagtggaa gaaaacagta gaggaggtgc tccatgattg aactttatga tagttacagt
    19681 caagaaagtc gagatttaca tgaaagtcta gtcgctactg gtctttctca acttggagtg
    19741 gtcatcgatg cagatggttt tctgcctgat ggtctgcttt ctccttttac ctattatcta
    19801 ggttacgagg atggaaaacc tctctatttt aaccaagttc ccgtttcaga tttttgggaa
    19861 attttaggag ataatcagtc tgcttgtatt gaagatgtga cgcaggagag ggctgtcatt
    19921 cattatgctg atggaatgca ggctcgcttg gttaaacagg tagactggaa agacctagaa
    19981 ggtcgagtac gtcaggttga ccactacaat cgctttggtg cttgctttgc taaaaccact
    20041 tatagcgcag atagcgagcc gattatgaca gtttaccaag atgtcaatgg tcaacaagtt
    20101 ttactggaaa accatgtgac gggtgatatc ttattgactt tgcctggtca gtccatgcgt
    20161 tactttgcaa ataaagttga atttatcacc ttctttttgc aagatttgga aatagatacc
    20221 agtcagctta tctttaatac tctagcgact cctttcttgg tttccttcca tcatccagat
    20281 aaatctggct cggatgtctt ggtatggcag gaacctctct atgatgccat tccaggtaat
    20341 atgcagttga ttttggaaag tgataatgtg cgtactaaga agatcatcat tccaaataag
    20401 gcgacttatg aacatgcttt agagttgact gacgagaaat accatgatca gtttgtgcac
    20461 ttgggttatc attaccagtt caaacgtgat aatttcctaa gacgagatgc cttaatcttg
    20521 accaattcag atcagattga gcaagtagaa gcaatcgcag gagccttgcc tgatgtcact
    20581 ttccgtattg cagcggtgac agagatgtct tctaagctct tagatatgct tcgttatcct
    20641 aatgtggccc tttaccagaa cgctagtcca cagaagattc aggagctgta tcaactgtcg
    20701 gatatttact tggatataaa ccacagtaat gagttgctac aggcagtgcg tcaggccttt
    20761 gagcacaatc tcttgattct tggctttaat cagacggtgc acaatagact ttatatcgct
    20821 ccagaccatc tatttgaaag tagtgaagtt gctgctttgg ttgagaccat taaattggcc
    20881 ctttcagatg ttgatcaaat gcgtcaggca cttggcaaac aaggccaaca tgcaaattat
    20941 gttgacttgg tgagatatca ggaaaccatg caaactgttt taggaggcta acatgtcaga
    21001 ggaagattta ttttacaaag acgttgaagg ccgcatggaa gagttgaaac aaaaacccat
    21061 caagaaggaa aaagaaaccc gaggggaaaa gattagtaag actttttcac ttttactggg
    21121 tttgatgatt ctgattggtt tgctctttac tttgctggga attttgaggt agatctatga
    21181 ttgacatact aattgtttta gctattatcc tatctcttgc tttgattgta ttggtaacta
    21241 tacaaccccg tcaaaatcaa ctattttcca tggatgccac tagtaatatt ggtaaaccaa
    21301 gctactggca gagcaacacc ttggtcaagg tgctcacttt attggtgagt ttggctttat
    21361 ttattctact attaaccttt atggtgatta cttataaata aaagaaaact tcagatcttc
    21421 accttttgtg gattggtctg aagttttctt ttttatactc aatgaaaatc aaagagcaaa
    21481 ctaggaagct agccgcaggc tgctcaaaac acggttttga ggttgtagat agaactgacg
    21541 aagtcagctc aaaacaccgt tttgaagttg tagatagaac tgacgaagtc agctcaaaac
    21601 acggttttga ggttgtggat agaactgacg aagtcagtaa catatataca gcaaggtgaa
    21661 gctgacgtag tttgaagagt attactgtct atatttttgg taaaaatcaa cttttacttg
    21721 gatgaaggtt ttggcttcac gtaggagttg aagaagggtg gcgcgggttt caaattcttc
    21781 tcttgtcttg ggcagactac ggttccggaa gacttccaga taacgttcaa tttcatctag
    21841 caaatcagaa gcaggattgg tctggctcag ttgacctgca atttttgaaa agagttgcgc
    21901 taagatcagg ctttcactgg cggcaaggtg acaagtgtta atctgttggg ccatgtttct
    21961 caggatacga ctttgtcgtt gtctcatctc aaagtagtgg atatggtagt cggtctggtg
    22021 aaagaggtgg tcagagtgat ccaaatagac cagtctgagg gcttctttca aaagcgtgtc
    22081 taattctgct accagctgtg ctcggttgcg tccgtctcct ctggataaat agtatttgaa
    22141 gcgctggagg atatctttta acttttcttc caccagcgtg tggtagtgct ggatttcctc
    22201 ttctcgtgaa ggcatataga gattaacaag caaggcaaat cctgtaccaa tagcaaagag
    22261 aaggaattcg ttgactagga ggtctggaga ggttgactct tgaaccaaga gatggctaac
    22321 caaaaccgtg cttggtgtga tgccaatttc ccagcccatc ttgtaggcta aaggaacgta
    22381 gaaggccaga tagaggccga gactccagat atgaaatccg ctcaagtgaa aagctagaac
    22441 accgatagcc agagctagaa gcatagaaaa aagacgattg cgagccagtt ttaaagtact
    22501 tctacgcgta tcagataggc tcaagagagc gataattcca gctgaaactg ctgacgaaag
    22561 attgagaaaa taagcaagca ggcaggcaag acaggtagct aagatgagct tggtcgtacg
    22621 ttggctaata gacataagaa tttcctaata agttagaata aaagcgtaaa agacaagaca
    22681 tgagcaggct tgccttgatg agttattttt tacgggttgc tgcgtattcg gcaacggcgg
    22741 taaagaggac atctgtagaa gagttaaggg ctgtttcaca tgagtcttgg atgacaccaa
    22801 tcacaaaacc aaccccaaca acttgtatgg caatatcgtt agaaataccg aaaaggctac
    22861 aagcaactgg gataagaagg agggaacctc cggcaatacc tgaagcacca caggctgaga
    22921 tagctgctac cacactgagg acaaaggctg tggcaaagtc aacaggaatt ccaagagtgt
    22981 taactgtaac aagggtcaaa aggttaatgg taatcgctac tccagccata ttgatagtag
    23041 aaccgagtgg gatagaaaca gaataggtat ctgggttgag tccaaggtca tggcagagtt
    23101 tcatgttgac aggaatgtta gtcgcagaac tacgagtgaa aaaggctgtc acaccgctga
    23161 cacggaggca gttccaaact agagagtaag gattgcgtct cataaagaag aaggcaatca
    23221 aagggttgac cacaggggca acaaaaagca tagtcgttac taatggaacc aataaaatac
    23281 cgtagttggc aaggcttccg actcccttgt cagaaatggt tttaaaaaca agaccaagga
    23341 ttccaaatgg agccagattg atgatccatt cgacaatttt agaagtcacg tcagcgatag
    23401 tttttagcaa ttctttacta tttttactgg ttttactggc ttctctcata gcgattccaa
    23461 aaatgactgc ccaagataag attccaatat agttagcagt aagcagggcg ttgactgggc
    23521 tgtcaaccag tttgagcaag aggttgctga ggacctgccc aatcccatct ggtggtgcaa
    23581 tttcagtatt ggcactattt agggtaattt caatagggac gatgaaactt gctagtacag
    23641 ctacaagagc agcggcgaaa gtccctatca taggatatac aagaaaacaa cagttttcat
    23701 attgctatct tgtccctttt gatgttggga aagggcattg gcaacgaggg caaagactag
    23761 gataggagca acagctttta gacctccaac gaataaatcc ccgagtagcc caatccctga
    23821 gagattagga agggtcagtc ctaggattcc ccataaagca taccaatcaa gatacgcttg
    23881 acaaggcttg ctttattcca agcatgaatg attcttttca taataatctc ctttttgtgt
    23941 agtgattatg attatagtat aaatgataga caaaatcaag aattttctgt ctattttttg
    24001 aatatttatg gagaatgaga ctgatgaaaa tatggtataa tgaaataaag gagttttata
    24061 tgcaaaaatt tattcaggct tatattgaaa agctagatgt gacaaccatt atcgagaata
    24121 ttctaaccaa ggtcatttct cttttactgc ttttgattgt attttatatt gctaaaaaaa
    24181 tgcttcatac catggtgcag agaattgtca aaccttctct aaaaatgtct cgtcatgatg
    24241 tcggacgcca aaaaaccatc tcacgtttac tagaaaatgt gtttaattat acgctatatt
    24301 tctttttact ctactgcatt ttgtcgattt taggtttgcc agtttctagt ttgctggctg
    24361 gagctggtat tgctggggta gcgattggta tgggagccca aggctttctg tctgatgtca
    24421 tcaatggctt tttcatcctc tttgaacgtc aactggatgt gggagatgag gtcgttctga
    24481 caaatggacc gattactgta tcgggtaagg ttgtcagtgt gggaattcgt acgacacagc
    24541 ttcgtagcga ggagcaagtc cttcactttg tacctaaccg aaatatcaca gttgttagca
    24601 atttctcacg cacagactag acctgttatt ttaagtaatt tgtggtacaa tagagggagt
    24661 ttaataagga gaaaagatgg ttttagaaaa gcagttgggc aatggttgta cctggataga
    24721 cctagaccta ggaaagttga ataaactaga agacctttct gaaatttacg gtttggacaa
    24781 ggaaaccatt gaatacgcac tggatagaaa cgagcgcgcc cacatggact accaccgtga
    24841 aagtgggacg gttaccttta tctataatgt cctagacgta aaaaaggaca aggcctacta
    24901 tgagactttt cccatgacct ttattgtcga gcatcgtcgc ctgattacca ttagtaatac
    24961 caagaacgcc tatgtcattg aacagatgac tcgttatctg gagaaccatg acacgctttc
    25021 gatttataag tttctctttg ccagtctgga aatcatcagc aatgcctact atcctgtcat
    25081 tgagcagatg gacaagagta gggatgaggt caatgacctc ttgcgccagc gaactaccaa
    25141 gaaaaacctc tttgccttgt ctgatttgga gactggtatg gtttatctga cggcagctgc
    25201 caaacaaaat cggattttgt tagagcatat tcaaggtcat gccttgtatc gtagttttga
    25261 tgagattgag agagaacagt ttgatgatgc catgattgag gctcatcagc tggtatccat
    25321 gacagaccta atctctcaga ttttacagca gctttcagcc tcttacaaca atattctaaa
    25381 caataatctg aatgacaatt tgacaacctt gactatcatt tcagtcttgc tagctgtttt
    25441 ggcagtcgtg acaggctttt tcggaatgaa tgttccctta cctttaacag atgagcccca
    25501 tgcttggctc tatatcagtt tggctagtgc aggtttgtgg attgttttat ccttgttact
    25561 aaggaaaatt gcgaaaaaaa gttaagaaaa ggagccagaa tggcgattga aaattatata
    25621 ccagattttg ctgtggaagc agtctatgat ctgacagtcc caagcctgca ggcgcaggga
    25681 atcaaggctg ttttggtcga tttggataat accctcattg cttggaacaa ccctgatggg
    25741 acgccagaga tgaagcaatg gctacatgac cttcgggacg cgggtattgg cattatcgta
    25801 gtgtcaaata acaccaaaaa acgcgttcaa cgagcagttg agaaatttgg gattgattac
    25861 gtttactggg ccttgaagcc cttcacattt ggtattgacc gtgccatgaa ggaattccac
    25921 tatgacaaaa aggaagtggt catggttggc gaccagctca tgacagatat acgagcagcc
    25981 caccgtgcag ggattcggtc aattttagtc aaacccttgg tccaacatga ctcaatcaaa
    26041 acgcagatta accgaactcg tgagcgtcgt gttatgagaa aaatcactga aaagtacgga
    26101 ccgattacat ataaaaaagg aatttaacta tggaagaaat tctctgtatt ggttgtggag
    26161 caaccattca gacgacagat aaggctggtc ttggttttac cccccagtcg gcacttgaaa
    26221 aaggtttgga gactggcgaa gtctattgtc aacgctgttt ccgtctccgc cactacaatg
    26281 aaatcacaga tgtccagttg acgaacgatg atttcctcaa gctcttgcac gaggtgggag
    26341 acagtgatgc tttagtggtc aatgttattg atatctttga ttttaatgga tctgtcatcc
    26401 caggtttacc acgtttcgtc tcgggcaatg atgtcctctt ggtaggaaat aaaaaagata
    26461 tccttcctaa gtcagttaag tctggtaaga ttagccagtg gctcatgaaa cgtgcccatg
    26521 aagaaggtct tcgtccagtc gatgtggtcc taacttcagc acaaaataaa catgccatta
    26581 aggaagtcat tgacaagatt gaacactacc gtaagggccg cgatgtctat gtggtcggtg
    26641 tgaccaacgt tggaaaatca actctaatca atgctattat ccaagaaatc acgggtgatc
    26701 agaatgtcat cactacttca cgcttcccag ggacaacctt ggacaaaata gagattccgc
    26761 ttgacgacgg atcttatatt tacgatacgc cgggaattat ccaccgccac cagatggctc
    26821 actacttgac ggccaaaaac ctcaagtatg tcagtcctaa aaaggaaatc aagcctaaga
    26881 cctatcagct taatcctgag caaaccctat ttttaggtgg tttgggacgc tttgacttta
    26941 tagcaggaga aaagcaagga tttactgctt tctttgataa tgaactcaaa ctccatcgta
    27001 gcaagcttga aggagctagt gctttctacg ataagcacct gggaactctt ctgacaccac
    27061 caaatagcaa ggaaaaagaa gatttcccaa ggctagtcca gcatgtcttt actattaaag
    27121 ataagacaga cctagtcatc tcaggcctag gctggattcg tgtaacaggc acagcaaaag
    27181 tcgccgtctg ggcaccagaa ggcgtcgccg tcgtcacacg aaaagcaatt atttaaaaca
    27241 aaatcgctga gcgaacaaag tgagctcata tagcgatagt tattgccgtg gtgtgattgc
    27301 caatctgtag attggcaagg ggcacaattg agaccaaggc tcaattgtga ggtcaggaaa
    27361 tccatttttc aaagatgaaa tctttggaaa attagttccg accgtccctc accacctaaa
    27421 ataactatca aaaaacaagg aagaaaatta tgtcattaac atcaaaacaa cgtgccttcc
    27481 tcaacagcca ggcacacacc ctcaaaccta tcatccaaat cgggaaaaat ggactcaacg
    27541 accaaatcaa aaccagcgtc cgtcaagctc ttgatgcgcg tgaattaatc aaggttactc
    27601 tcttacaaaa cacagatgaa aacatccacg aagtagctga aattttggaa gaagaaatcg
    27661 gtgtggatac agtccaaaaa ataggacgca tcttgatttt gtttaaacaa tctagcaaga
    27721 aagaaaatcg caagatttct aagaaagtca aagaaatcta agaccgaaac tccaaataac
    27781 tgtttttata gagaaataaa ggggactagc ctatgacaat cgaactattg actcccttta
    27841 ccaaggtaga gttggagcca gaaatcaagg agaaaaaacg caaacaagtt gggattttag
    27901 gggggaattt taaccctgtt cacaatgccc atctcattgt tgcggatcaa gtacggcaac
    27961 agttgggact ggatcaagtt cttctcatgc ctgaatacca acctcctcac gttgataaaa
    28021 aggaaaccat tcctgaacac catcgtctca agatgcttga gttggcaatt gaggggattg
    28081 acggcctagt cattgaaacc attgagttgg agcgcaaggg tatttcctac acctacgaca
    28141 ccatgaaaat cttgacagag caacatccag atacggatta ttactttatc atcggtgccg
    28201 acatggttga ctatctgcct aagtggtacc gaattgatga actggttgac atggttcagt
    28261 ttgtgggggt tcagcgtcca cgctacaagg cagggacttc ctatccagtt atctgggtgg
    28321 acgtaccgct catggatatc tcgtccagca tggtgcggga cttcattgcc caaggtcgga
    28381 aacccaactt tctcctacct cagccagtgc tagactacat cgagaaggag gggctctact
    28441 gatgtcctat caagactata tcaactgctc ccgtgaggcc ttgttggaaa aaatggcaga
    28501 gcttctacct gagaaacgtc taacccattg tctaggtgtg gagcgtgccg ctatggagtt
    28561 agctcagcgc tttggtgtag atgttgagaa agcaagtcta gcaggtcttc ttcatgacta
    28621 tgctaaaaag ttgtcagatc aggaatttct agacttgatt gaccgttacc agctagaccc
    28681 tgacctcaaa aactggggta ataatgtctg gcatggtatg gtcggaattt acaaaattca
    28741 ggaagatttg gatttgcatg attcagaaat cctgcgagcc attgaagtcc atacagtcgg
    28801 tgctggtcaa atgacagacc tagataaggt catctacgtc gcagactata tcgagcacaa
    28861 tcgagccttt cctggagtag atgtggcgcg tgagattgca agtctatcgc tcaataaggc
    28921 ggtggcctac gaaacagctc gtaccgtgga gtatctagct catcagggat tccccatcta
    28981 tccccaaacc cttgaaacct ataacgcctt tgtgcactat ttgaaagaga actaaatgaa
    29041 gacggctttt ataatcattg atgttcagaa tgttttagta gaaactgggt tccagacaaa
    29101 aagtctattg ggaaaaattt cttatttaca aaaccaggct agaagcaaga atattgaaat
    29161 tatctatgtt caacatattg agaactctga agctcaaaca tcagaagatt ggcagttatc
    29221 tgcactttta aatcgaaaac ctgctgaaaa ggtctttcag aagaagtata acagtatttt
    29281 caaagaaact ggcttaaaag aatacttgga taagcagggg attgaaaaat tagttttatg
    29341 tgctatgcag acagaatatt gtgtggatac ctctgtcaag gttgcctttg aatatggcta
    29401 tcagcttatt gttccagaag gtgctgtcac aacctttgat ggggatgaca ttccagcaga
    29461 aacgattaat gaattttatg aggacatttg ggaggagcgc tttgcagatg tcctagatta
    29521 caaacatatt ttctaaaaag aggattaaat gaacgaaaaa gaattactag aactagtcgt
    29581 gaaagcggct gatgagaaac gtgcggagga tatcctcgca cttgatgtac aagatttgac
    29641 tagtgtgacg gactactttg tcatcactag ctcaatgaat agccgtcagt tggacgctat
    29701 cgcagctaat atccgtgaaa aagtagctca agcgggcttt aaaggtagcc atgtcgaagg
    29761 cgatgcagct ggaggctggg tcttactgga cctcggtgct gttgtcgtgc atatcttttc
    29821 agaagaaatg cgtgcccatt ataatctaga gaagctatgg catgaggcga attcagtaga
    29881 tatttcagaa gctcttgctt agaagatgaa ctcagttgta gtcaactggg tttctttgct
    29941 tattttagaa aaattgatag aaaggtaaag ggctagtggt gtttaccatg gagctcttag
    30001 tatcatgatt atggcgactt atgaaacctt tgcggcggtc tatgatgcgg tcatggacga
    30061 tagtttatac gacaaatgga caaatttttc tctgcgtcat ttgcctaaga ccaaggagaa
    30121 aaagaaactc ttggaactgg cttgtgggac aggaattcaa tcagtgcgct tctctcaggc
    30181 tggttttgat gtgactggac ttgacttgag tgcggatatg ttgaagattg cggagaagag
    30241 agcaacttca gccaagcaaa agattgcttt tatagaaggt aatatgctga atttgtccaa
    30301 ggcagggaaa tacgattttg tcacgtgtta ttcggactct atctgctata tgcaggatga
    30361 ggtggaagta ggggacgtct ttaaggacgt gtacaatgcg ctgaatgaag agggagtttt
    30421 catctttgac gtgcactcga cctaccagac agatgaagta ttccctggct attcctacca
    30481 tgaaaatgcg gaagattttg ccatgctttg ggatacatat gaggacgaag ctcctcactc
    30541 catcgtgcat gagctgactt tctttatcaa ggaggctgac ggttccttta gtcgccacga
    30601 tgaagtacat gaggagagga cctatgagat cttgacctat gatatcttac tggaacaggc
    30661 tggattcaag tccttcaaac tctatgcaga ctttgaggat aaggaaccaa cagaaactag
    30721 cacccgttgg ttttttgtgg cgcagaagta ggagattagc atgaccatca caggtattat
    30781 cgcggagttc aatccttttc ataatggcca taaatacctg ctggatcagg cagagggact
    30841 gaaaattgtt gccatgtcag ggaatttcat gcagcgtgga gagcctgcta ttgtggataa
    30901 gtggacaagg gcccagatgg cgctggaaaa tggcgcagac ttggtagtgg aattgccctt
    30961 tttagtcagt gttcaggcag ctgatttctt tggtcaagga gctgtggata tcttggatcg
    31021 cttgggcatt gatagtctag tttttgggac agaggaagtt cgagattatc agaaaatcgc
    31081 tgacttatac acagagaaag gtgctgagat ggagaaattt gtggaaaatc tgcctgattc
    31141 cctttcctat ccccagaaaa cccaatctat gtggaaggaa tttgctggtc ttgatttttc
    31201 aggtaatacc cccaatcatg ttcttgctct ggcctatgca aaggcggttg caggacgaaa
    31261 tatcaagctg catccgattc agcgtcaggg ggcaggttac cattctgtga ataaagatgt
    31321 ggactttgcc tcggcgacag ccctccgtca acatcagaag gaccaagatt tcttagaacg
    31381 ctttatgcct tctgttgccc tatttgagca ggccagtaag gtgatctggg aagactattt
    31441 tcccttgctc cgctatcaaa tcttgtcaaa tcccgaccta accaccatct atcaggtcaa
    31501 tcaagaaatg gctgtgcgca ttaaagaagc tattaaaaca gcccagtctg tagaagagtt
    31561 ggtcgaggcg gttgcgacca aacgttacac caaggcgcgt gtcagacgcc tattgaccta
    31621 tattttggtg caggctagag aaaatgtctt gccagaagcc attcatgtcc ttggatttac
    31681 tgaaaaaggc aggcaacatc tcaagtctct gaaaggacag gtcaatctag tcagccgaat
    31741 tggcaaagaa ccttgggatg ctatgaccca aaaagcagac cagatttacc aactaggaaa
    31801 gccaagtata gcagagcaaa attttggaag agtgccgatt agaatagaaa caagctaagt
    31861 ctaccgaaag gtaggctttt tgagattttt tacgaataat actcttcgaa aatcaaattc
    31921 aaatcgcgtc aacgtcgcct tgccgtactc aagtacagcc tgcggctagt ttcctagttt
    31981 gctctttgat tttcattgag tataaataga tagaaaagaa aatcctgtac aagttcctga
    32041 caatttcttt cttttcgtgt ataatagtgg aaaagagcta aaacgaggta tggttatgga
    32101 agcagtcctt tactcaacat tccgaaatca tttaaaggac tacatgaaga aggtaaatga
    32161 tgaatttgag cctttgacgg tggtcaataa aaatccagat gaggacattg tagttctttc
    32221 aaagagcgaa tgggacagta ttcaggaaac cctgagaatc gctcaaaata aggagttatc
    32281 agacaaggtt ttgcgaggaa tggctcaagt ccgtgctgga agcattcagg tccatgtgat
    32341 tgaggagtga tgaatgctac tcaagtttac agaagatgcg tgggcagatt attgctactg
    32401 gcaaaaccaa gataaaaaaa cactaaaaag aatcaataaa ttaatcaagg atattcaacg
    32461 cgatccattt acaggaatag gaaaaccaga gccactcaaa tatgattacc aaggagcctg
    32521 gtcacggcgt attgatgcag aaaatcgctt gatttatatg atggatggag atagcgtggc
    32581 tttcttgtcc tttaaagatc attactaagt ctattgaaag gtaggctttt tctcaagtct
    32641 ctactaaact actatttcta aaaaacaagt ttattttggc aaatgtgttc caaatttccc
    32701 aaaacatatt ctattttagg tttgtgaaaa tcactttttt atggtagaat gtaaaagaat
    32761 gtatgtcatt cggaataaca ataaaatgag gtaaaaacat ggaaatcatg tcgcttgcga
    32821 ttgctgtttt tgccgtcatc attggtttag tcattggata tgtcagcatc tcagctaaga
    32881 tgaaatcatc tcaggaagct gcagagttga tgcttttaaa tgctgaacaa gaagcaacta
    32941 atttacgtgg acaagctgag cgtgaagcgg atttacttgt taatgaagcc aaacgtgaaa
    33001 gcaagtctct taaaaaagaa gcactattgg aggccaaaga agaagccaga aaataccgtg
    33061 aagaagtgga cgctgaattc aaatcagaac gtcaagaact caaacaaatc gaaagtcgtt
    33121 tgacagagag agctactagc cttgaccgta aggacgacaa tttgacgagt aaagaacaaa
    33181 cacttgaaca aaaagaacaa agtatttctg atagagcgaa aaaccttgat gcgcgtgaag
    33241 agcaattaga ggaagtcgaa agacaaaaag aagcagaact agagcgtatt ggtgctctgt
    33301 ctcaggcaga agcacgagat attatcttgg ctcagacaga ggaaaacttg accagggaga
    33361 ttgccagtcg cattcgcgaa gctgagcaag aggtcaagga acgttctgac aaaatggcca
    33421 aggacatctt ggttcaagct atgcaacgta tcgctggtga atatgtagcg gagtcaacaa
    33481 actcaacagt tcatctgcca gacgatacta tgaagggacg cattattggt cgtgaaggtc
    33541 gtaacattcg tacctttgaa agtttgacag gggtcgatgt gattatcgac gatacaccag
    33601 aagtggtgac cttgtcagga tttgatccga ttcgtcgtga gattgcccgt atgactatgg
    33661 aaatgttgct caaagatggt cgtatacatc cagctcgtat cgaagagttg gttgagaaaa
    33721 accgtcaaga gattgacaat aagattcgtg aatacggtga ggctgctgcc tatgaaattg
    33781 gtgcgccaaa ccttcatcca gacttgatga agattatggg acgtttgcag ttccgtactt
    33841 catatggaca aaatgttttg cgccattcga ttgaggttgc taagttggct ggtatcatgg
    33901 cgagcgaact tggtgaaaat gcggctcttg cccgtcgtgc tggattcctt cacgatatcg
    33961 ggaaagccat tgaccatgag gttgaaggta gccacgttga aatcggtatg gaattggccc
    34021 gtaagtacaa ggaaccccca gttgtggtga atacgattgc tagtcaccac ggagatgttg
    34081 aagctgagag cgtgatagca gttatcgtcg ctgcagcaga tgccttgagc gcagcccgtc
    34141 caggtgctcg taatgagtct cttgaaagct acatcaagcg tctccatgat ttggaagaaa
    34201 ttgctaacgg ctttgaagga gtgcaaacta gctttgccct tcaagcagga cgtgaaattc
    34261 gtatcatggt caatccagga aaaatcaagg acgacaaagt cacaatcttg gctcacaaag
    34321 ttcgtaagaa aattgaaaac aatctcgatt atccaggaaa tatcaaggta accgtgattc
    34381 gcgagcttcg tgcagtagat tatgctaaat aaataagaaa gagcagttga aaaattactg
    34441 cttttttgtt acactagata gaaagactgt aaaggataat ctggcttttt gccattattc
    34501 tagagaaatg ttatttcaca gattgactaa aaggagacac aatggcagac cgaggcttac
    34561 taatcgtttt ttctggtcct tcaggggttg gaaaaggaac ggttagaaga gagatttttg
    34621 agagttctga aaaccaattt caatattctg tatcgatgac gacacgcgca caacgtcctg
    34681 gagaagtgga cggtgttgac tatttcttcc gtactcgtga agaatttgaa gagctgattc
    34741 gtcaaggaca gatgttggaa tacgcagaat atgtcggcaa ctactatgga actcctctga
    34801 cctatgtcaa tgaaaccttg gacaagggaa tcgatgtttt ccttgaaatt gaagttcagg
    34861 gtgctcttca ggtcaagaaa aaggttccag atgctgtctt tatcttcctg acaccaccag
    34921 atttggatga attgcaagat cgcttggtag gtcgtggaac agatagtgca gaagtgattg
    34981 cccaacgaat cgaaaaggcc aaggaagaaa ttgccctcat gcgtgagtat gattatgcga
    35041 ttgtcaacga tcaggtgccc ctagctgctg aacgtgtcaa atgtgtgatt gaagcagaac
    35101 acttctgtgt ggatcgtgtc attggtcact atcaggagat gttaccaaaa tctccaacta
    35161 cccgataaaa tttagaaaat aggtacaagc aaatgatgtt aaaaccctct attgatacct
    35221 tgctcgacaa ggttccttca aaatattcac tcgtaatctt ggaagcaaaa cgtgcccacg
    35281 aattggaagc aggtgcccca gcaactcaag gtttcaagtc tgaaaaatca actcttcgcg
    35341 ctttagaaga aatcgaatca ggaaacgtta caattcaccc agatccagaa ggaaaacgtg
    35401 aagcagtgcg tcgccgtatc gaagaagaaa aacgccgcaa agaagaagaa gaaaagaaaa
    35461 tcaaagagca aattgctaaa gaaaaagaag atggtgaaaa aatttaaggt tggggggact
    35521 caatcttatt ttttctattg caagaatgta ctgacaagga ggaggtgaga agatggccct
    35581 agctaagatt atcgtagatg tgcccttgat gcagacggac cagccctata gttacaggat
    35641 tccggaggaa tttgagggaa tgctggaagt tgggatgcgg gttcatgtgc cttttggtaa
    35701 gggtaatcgc ctgattcaag ggattgttct tggtttgaag tcccaatcag atggagaaga
    35761 gatggagcaa gatttaaaag atattgcaga ggtgctggat ttttctcctg ttctcacgcc
    35821 agaacaactc tggctggctg aggagttacg caaatctgtc ttctcctaca aaatctctat
    35881 cctcaaggcc atgcttccag ggtttctgaa ttctagctat gacaagattc tctatcctct
    35941 ggaaggcttg agtcaggaag aacgagtacg cctgtttggt tcagaagatt cgctagcctt
    36001 ttcttcacta gaccttgcca agcaagctga aatgatgcgt ttgactagaa aaggcctgct
    36061 tggtctggaa tatcaggcag tcgatcaaaa gaaggtcaag acccagtctt ggtatgaggt
    36121 tgaccatgcc caattagaag gtgttgagat ttctacacgt gccaagaaaa agttggaact
    36181 gagagattat ctgctgtctc atccagagag cgcttccttg gctagcttgt tagagtccta
    36241 ctcgcgagag caagtcaact tctttgtgga tcaaggtgct gttaccatag tccaaaagga
    36301 agttcaacgc tcggctgctt attttgaagg aattgaagca agtagacctt tggagttaaa
    36361 tccagaacaa agacaggcgc gtgatgcggt tgtgagttct attggcagtt ctcaacctcc
    36421 ctttctactt caagggatta caggaagtgg gaagaccgag gtttacttgc agattatcca
    36481 aggtgccctg gataagggta agacagctat tttgctggta cctgagattt ccttgactcc
    36541 tcagatgacc gagcgtttta tagcacgttt tggggacaag gtagccattc ttcactcagg
    36601 attatccaat ggcgaaaagt atgatgaatg gcgcaaggtg gagcgtggcg atgcccaagt
    36661 tgttgttggt gccagatctg ctatctttgc tcctctgaaa aatctgggtg tcatgattat
    36721 tgatgaagag catgaagcgg cttataagca ggacagcaat ccccgttacc atgccagaga
    36781 ggtagctatt ttacgggctc agtataatca agcaactctg gtacttggat ctgcaacgcc
    36841 gagcttagag agccgggcgc gtgctggcaa aggcgtctat caacacttac gtctaaccca
    36901 acgtgccaat cctttggcta caatccctga ggttcaagtg attgactttc gagactatat
    36961 cggacaaaat gagacgtcaa actttacgcc tcctttgcta gaggctatcc aagaccgtct
    37021 ggttaaaaaa gagcaggtgg ttctcatgct caatcgccgt ggttattcta gctttgtcat
    37081 gtgtcgggag tgtgggacgg tggatacttg tcccaactgc gatatttctc tgaccttgca
    37141 tatggatacc aagactatga actgccatta ttgtggtttc tcgaaggata ttcctcaggt
    37201 ctgtcctaac tgtaagagcc acagtattcg ttactatggg acgggaactc agaaggctta
    37261 tgatgagcta gcagaactct ttccccaagc tcgcattctg aggatggatg tggatacgac
    37321 tcgaaaaaaa ggcagtcacc aagccttgct tgatcagttt gggcgaggga aagcggatat
    37381 tttacttggt actcagatga ttgcaaaggg tttggatttt cccaatgtta ccctagtcgg
    37441 agttctaaat gcggatacgg ccttgaatct gcctgatttc cgttcttctg agagaacctt
    37501 ccagctcttg actcaggtgg caggtcgagc aggtcgggct gaaaaagcag gtcaagtctt
    37561 gatacagtcc tacaattcgc agcactatgc tattcgattt gccaaggatc aagattacga
    37621 aggcttttat gcctatgaaa tgggaatcag acgacaactc ggctatccac cttactattt
    37681 cacgattggt attacccttt ctcacaagaa agaagaagag gttttcaaac gtgcctatga
    37741 agtcatgaac attttgcggt caggcttgtc agagaccagt cccattctgg ggccaacgcc
    37801 aaaaccgatt gcccgtaccc acaacctcta tcattaccag attttaatta aataccgttt
    37861 agaagatgag ctggggccga ccctcaacca ggtcttggcc ttgactcaag aacgggaaaa
    37921 tagtgagctc cgtctcagca ttgaccatga gccgcagcaa tttttataaa aaggagaaga
    37981 tatgacaaaa ctaatcttta tggggacccc cgacttttca gcaacagtct taaaaggact
    38041 tttgacagat gaccgttacg aaattctagc cgttgtgacc cagccagacc gtgctgttgg
    38101 tcgtaaaaaa gttatccaag aaaccccagt caagcaggct gccaaggaag caggactatc
    38161 tatctaccaa cctgaaaaat tatctggaag tccagagatg gaagatctta tgaagctagg
    38221 agcagatgga attgtgactg ctgcttttgg gcagtttctc ccaagcaaac tccttgatag
    38281 catggacttt gctgtcaacg ttcatgcctc cctccttcct agacaccgtg gtggtgcgcc
    38341 tatccattat gccttgattc aaggggatga ggaagctggt gtgaccatca tggaaatggt
    38401 taaggaaatg gatgcaggag atatgatttc tcgtcgcagc attccgatca cagatgagga
    38461 caatgttggc accttgtttg aaaaattggc gctagttggt cgtgatttgc ttttggacac
    38521 tctgcctgcc tatattgctg gtgatatcaa acctgaaccg caggatacga gtcaggttac
    38581 cttctctcca aatataaagc cagaggaaga aaaactggac tggaacaaaa ccaatcgtca
    38641 actctttaac caaattcgtg gaatgaaccc ctggcctgtt gcccatactt tccttaaggg
    38701 cgaccgcttt aagatttatg aagccctacc agtagaaggt cagggaaatc caggtgagat
    38761 tctctctatc ggcaagaaag aattgattgt cgcaacggct gaaggggctc tatccctcaa
    38821 acaagtgcag ccagctggta agcctaagat ggacattgct tccttcctca acggagttgg
    38881 acgtacattg actgtaggag aacgatttgg tgactaaagt agaaacggct agaagtttag
    38941 ctctagcagt gctagaggat gtttttgtga accaagcata ctcaaatatc gccttaaata
    39001 agcatctaaa gggaagtcaa cttttggcag cagacaaggg cttagtgacc gagctggtct
    39061 atggaacggt agcccgtaaa ctgactctgg aatggtacct atcccacttt atcgaagaca
    39121 gagaccagtt agacagctgg ctctatgtcc ttcttctcat gagtgcctac caactccgct
    39181 atttggacaa gattccagat catgctgtgg tcaatgaagc agtggaattg gccaaactcc
    39241 gtaaaaaagg cagtgaaaaa ttggtcaacg ctgtccttcg ccgtatcttg cgtgaaggct
    39301 ggccagatat tgctagcatc aagcgaaaaa acaagcgtga ctccattgcc tattctctcc
    39361 cagtttggct agttgccaaa ctcaaggaag aatacggaga ggagagagca aaagccatct
    39421 ttgaaagcct gttagtgcga aacaaagcca gtattcgtgt aacagaccta agtcgaaaag
    39481 aggaaatcca agccttgttg gaggcgaata attccctttt agcaaccact ggtctggtta
    39541 aggagcaagg gcattttgca gggcataatt tgtttgcgga tggagccatt accatccaag
    39601 acgagtccag tcagctggtt gctccgacgc ttgatttaca aggtgatgag cgagtgcttg
    39661 atgcctgtgc ggctccaggt gggaaaacag cccatatagc ctcttatctt acgacaggtc
    39721 aggttactgc tctggacttg tacgaccaca agttggattt aattcaagaa aatgcccaac
    39781 gtctgggagt tgcagatcgg gttcaaactc aaaaattgga tgccagaaag gtgcatgagt
    39841 tttttgacca ggattccttt gataagattt tggtggatgc tccttgttca ggaatcggtc
    39901 ttttgcgccg aaaaccagat atcaaataca ataaagaaac ggcagatttc gcgtccttgc
    39961 aggaaattca gttagaaata ttaggtagtg tttgtcaaat actaggcaaa ggtggtataa
    40021 taacttatag cacctgcact atcgtctcag aggagaattt tcaagtcgtt aaggcctttt
    40081 tagagagtca tcccgagttc gagcaggtaa aactagaaca tgaatgtaag gatatcatga
    40141 aagacggctg tatcctcatt acacctgaat tgtatggaag tgatggattc ttcatcagtc
    40201 aatttcgcaa gatatcggat taggaaggaa ctgacacatg gaaatttcat tattaacaga
    40261 tgttggtcag aaacgaacaa ataaccaaga ctatgtcaac cactatgtca atagagctgg
    40321 acgtaccatg attattttag ctgatgggat gggaggtcat cgcgcaggga atatcgctag
    40381 tgaaatggcg gtcacagacc tgggtgtagc ttgggttgat acccagatcg atacagtcaa
    40441 tgaagtgcgt gaatggttcg cccattacct agaaattgaa aatcaaaaga ttcaccaact
    40501 tggtcaggat gaagcttaca gaggcatggg aactactttg gaagtccttg ctattattga
    40561 taatcaggct atctatgctc atattggtga ttcgcgtatc ggcttgattc gtggagaaga
    40621 ataccatcag ttgacgagcg atcattcctt ggttaatgaa ttgctcaagg ctggtcaatt
    40681 gacaccagaa gaggcagaag ctcatccgca aaaaaatatt atcacccagt ctattgggca
    40741 aaaagatgaa attcagcctg attttgggac agttatcctt gagtcaggtg actatctctt
    40801 gctcaatagt gacggcttga ccaacatgat ttcaggcagt gagattcgtg atattgtaac
    40861 cagtgatatt cctttagcag ataaaacgga gacacttgtt cgttttgcta acaatgcagg
    40921 aggtttagac aacattacgg ttgcccttgt ttctatgaac gaggaggatg cagaatgatc
    40981 caaatcggca agatttttgc cggacgctat cggattgtca aacagattgg tcgaggaggc
    41041 atggcggatg tctacctagc caaagactta atcttagatg gggaagaagt ggcagtgaag
    41101 gttctgagga ccaactacca gacggacccg atagctgtag ctcgttttca gcgtgaagcg
    41161 agagctatgg cagatctaga ccatcctcat atcgttcgga taacagatat tggcgaggaa
    41221 gacggtcaac agtacctagc tatggagtat gtggctggac tggacctcaa acgctatatc
    41281 aaggaacatt atcctctttc taatgaagaa gcagtccgta tcatgggaca aattctcttg
    41341 gctatgcgct tggcccatac tcgaggaatt gttcacaggg acttgaaacc tcaaaatatc
    41401 cttttgacac cagatgggac tgccaaggtc acagactttg ggattgctgt agcctttgca
    41461 gagacaagtc tgacccagac taactcgatg ttgggctcag ttcattactt gtcaccagag
    41521 caggcgcgtg gttcgaaggc gactgtgcag agtgatatct atgccatggg gattattttc
    41581 tatgagatgt tgacaggcca tatcccttat gacggggata gcgcggtgac cattgccctc
    41641 cagcatttcc agaaacccct gccgtccgtt attgcagaaa atccatctgt acctcaggct
    41701 ttagaaaatg ttattatcaa ggcaactgct aaaaagttga ccaatcgcta ccgctcggtt
    41761 tcagagatgt atgtggactt gtctagtagc ttgtcctaca atcgtagaaa tgaaagtaag
    41821 ttaatctttg atgaaacgag caaggcagat accaagacct tgccgaaggt ttctcagagt
    41881 accttgacat ctattcctaa ggttcaagcg cagacagaac acaaatcaat caaaaaccca
    41941 agccaggctg tgacagagga aacttatcaa ccacaagcac cgaaaaaaca tagatttaag
    42001 atgcgttacc tgattttgtt ggccagcctt gtattggtgg cagcttctct tatttggata
    42061 ctatccagaa ctcctgcaac cattgccatt ccagatgtgg caggtcagac agttgcagag
    42121 gccaaggcaa cgctcaaaaa agccaatttt gagattggtg aggagaagac agaggctagt
    42181 gaaaaggtgg aagaagggcg gattatccgt acagatcctg gcgctggaac tggtcgaaaa
    42241 gaaggaacga aaatcaatct ggttgtctca tcaggcaaac aatccttcca aattagtaat
    42301 tatgtcggcc ggaaatcttc tgatgttatc gcggaattaa aagagaaaaa agttccagat
    42361 aatttgatta aaattgagga agaagagtcg aatgagagtg aggctggaac ggtcctgaag
    42421 caaagtctac cagaaggtac gacctatgac ttgagcaagg caactcaaat tgttttgaca
    42481 gtagctaaaa aagctacgac gattcaatta gggaactata ttggacggaa ctctacagaa
    42541 gtaatctcag aactcaagca gaagaaggtt cctgagaatt tgattaagat agaggaagaa
    42601 gagtccagcg aaagcgaacc aggaacgatt atgaaacaaa gtccaggtgc cggaacgact
    42661 tatgatgtga gtaaacctac tcaaattgtc ttgacagtag ctaaaaaagt tacaagtgtt
    42721 gccatgccga gttacattgg ttccagcttg gagtttacta agaacaattt gattcaaatt
    42781 gttgggatta aggaagctaa tatagaagtt gtagaagtga cgacagcgcc tgcaggtagt
    42841 gtagaaggca tggttgttga acaaagtcct agagcaggtg aaaaggtaga cctaaataag
    42901 actagagtca agatttcaat ctacaaacct aaaacaactt cagctactcc ttaaaagcag
    42961 atggataatc aaaatgagta atcaatcttt gtcatgattt catggcaaag attttttttg
    43021 agtccagatt tgtgatagaa tagagggagt tgataaaagg aggaaagcat ggaagaatca
    43081 aaagaattaa atgccgtcat tgatgtgatt atgctagcgg ggactattct ccttaaaagt
    43141 ggctcagaaa tccatcgtgt agaagatacc atgattcgaa tcgcgcattc gcaggggatt
    43201 gtggattgca atgtccttgc catgcctgcc gctatctttt tctctattga aaataccaat
    43261 atttcgcgca tgaagcgcgt gacctcctct tcttataaca tcgaaaaagt ctgcgatgtg
    43321 aaccagattt ctcgtcagct agttgggggg cagattgact tagaaacagc ctttaagcaa
    43381 ttgacggcct tgcaagctca accccttccc tatactaagt tgcaggtaac tctggctgcg
    43441 acctttagtg ctcctttctt ttcagttatg tttagcggaa atatctacga cgcacttggg
    43501 gcaggagtgg cgaccttatt tggttttgcc ttttccctct atgtggaaaa atttatccga
    43561 attccctttg tgacagcctt tgctggagcc tttgtctttg ggataattgc ccagttttgg
    43621 gctcgctaca caggttttcc ttcaacggca gatttgatta tagctggtgc ggtcatgccg
    43681 tttgtaccag gtattgcctt gaccaatgcg gtccgtgata ttatgaccaa ccacataaac
    43741 tctggtatga gtaagatgtt tgaatccctg ctcattaccc tcgctttagg ggcaggaact
    43801 tctgtcgcct tggtattgat gaactaatat gacactaaca acctttttat tacaagcagt
    43861 agcaagtttt cttgccatta tcactttttt aatcgtactc aatgtgcaac ggtctatgct
    43921 cttacctgga gggattttgg gcatgactgt ctggctaatc tatctcttgc tcaaggaacc
    43981 gaccaatgtc attgtagcta ccttcattgc agccattatt ggttcttgtg tcagccagat
    44041 tttaagtatt ctttataaga cacctgctgt ggtctttatc ttggccattt tggcaccgct
    44101 ggttccaggt tatctctcct accgaacaac tgcctttttt gtgacagggg actataataa
    44161 agcactggca agtgcgacct tggttgtcat gttggctttg gtaatctcta ttggaatggc
    44221 tagcggaaca gtgattctca gactgtatca ttatataaaa acacatcgag tatcgtagac
    44281 tttacagaaa taaaagaatt ttctgaaaaa tgagataaat aaattaacaa cgctttctat
    44341 atgtgcgaga ataccgcact tatgaagaaa ttgcggctga ttttggtatc cacgaaagca
    44401 acttactccg tcggagccaa tgggttgaag taactcttgt tcaaaggtgg tgttacgatt
    44461 tcaagaactc ctctcagttc tgaagacacg gtaatgattg atgcgacgga agtaaaaatc
    44521 aatcgcccta aaaaaaacaa ttagcgaatg attctggtaa aaagaaattt cacgctatga
    44581 aggctcaagc gattgtcaca agtcaaggga gaattgtttc tttggatatc actgtgaact
    44641 attgtcatga tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa gctggtaaaa
    44701 tcttggctga cagtggttat caagggctca tgaagatata tcctcaagca caaactccac
    44761 gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctataac catgcgctat
    44821 ctaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt
    44881 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgctggca
    44941 ttatcaatca tgaactagga ttctagtttt gcaggaagtc tactactttc cttattgtct
    45001 gtaaatctac tgaccttgtt gtttatccca gtcatggttt ctagttcggg ctcagagttt
    45061 caaagtggat ggcaagagca tcaattgatt gctgagaagg ttagtaaaac acttgataag
    45121 acatttgata aggatgtcag agaaattccg accagtcagt tttatcaaaa atttgtagat
    45181 gagatgggaa ggacttactc aggaaatttg atcctccagg agctgataac tgtgaatgga
    45241 gcttataaag ctacttatat cggtgaactc tctagcaact aatcattctt taaaatgatg
    45301 accaataaga ggcttgattt ggtgaatcaa gtcttttttc tctcttttac tgccatttgt
    45361 gataaaatag tatagaacga ttttttacat gaatgataaa acagaggtaa atatgacaat
    45421 cggtattgat aagattggtt ttgcgaccag tcaatatgtc ttgaaattac aagacttagc
    45481 agaagcgagg ggaattgacc ctgaaaaatt aagtaaagga ctcttactca aggaattgag
    45541 tattgcgccc ctaactgagg acattgtgac cttggcggcc agtgctagtg actctatttt
    45601 aactgagcaa gaaagacaag aagttgacat ggtcattgtg gctaccgagt caggaattga
    45661 ccagagtaag gctgcggccg tctttgtgca tggcttgctg ggcatccagc cctttgctcg
    45721 tagtttcgag attaaagaag cctgttatgg agcgactgct gcccttcatt atgccaaatt
    45781 gcatgtggaa aattctccgg agtccaaggt cttggtcatt gccagtgata ttgccaaata
    45841 cggtattgaa actccaggag aaccaactca aggtgctgga agtgtagcta tgttgattac
    45901 acaaaatcca cgcatgatgg cctttaataa tgacaatgta gctcagaccc gtgacatcat
    45961 ggatttctgg cgaccaaatt actcgacaac tccttatgta aatggtgttt attctaccca
    46021 acaatacttg gatagtttga aaacgacttg gcttgaatat caaaaacgct accagcttac
    46081 tctggatgat tttgcggctg tttgtttcca cttgccttat cctaaattag cgctaaaagg
    46141 cttgaaaaaa atcatggata agagcctgcc tcaagagaaa aaagacctct tacaaaagca
    46201 ttttgaccag tctattctct acagtcaaaa ggtggggaat atctacacag gttcactttt
    46261 ccttggactt ttgtctctct tggaaaatac agatagcttg aaagctgggg ataaaatcgc
    46321 cctttatagt tacggaagtg gagctgtggc tgagttcttc agtggtgaat tggttgaagg
    46381 atatgaagct tatttggata aagaccgttt gaacaagctc aaccaacgaa ctgccctatc
    46441 cgttgcagac tatgaaaagg tcttttttga ggaagtaaac ttggatgaaa caaactctgc
    46501 ccagtttgct ggctatgaaa atcaagattt tgccttggtt gaaattcttg accaccaacg
    46561 ccgttatagc aaggttgaaa aataatgaag ataagttgga atggattttc taaaaaatca
    46621 taccaagagc gcctcgagct gctaaaagct caggcgctcc ttagtcctga gagacaagct
    46681 agtctggaga aggatgaaca gatgagtgtg actgtggcag accagctgag tgagaatgtg
    46741 gtgggaactt tttctctgcc ttattcgctg gttccggagg tacttgtcaa cggtcaggaa
    46801 tacaccgttc cctatgtgac agaagaaccc tctgtggttg cggcggccag ctatgccagc
    46861 aaaatcatca agcgtgcagg tggttttact gcacaagtcc atcagcgcca gatgattggg
    46921 caggtagccc tttatcaagt tgctaatcct aaactagcgc aagagaagat tgccagcaag
    46981 aaagcggagc tcttggagct tgccaatcaa gcctatcctt ctatcgttaa acgtgggggt
    47041 ggggcgagtg acctgcatgt cgagcagata aaaggtgaac cagactttct cgttgtttat
    47101 attcatgttg atacccagga agccatgggt gccaatatgc tcaacaccat gctggaagcc
    47161 ttgaaaccag tcttagaaga actcagtcag ggacagagtc tcatgggaat cctgtccaac
    47221 tacgcgaccg attctctggt gactgcaagc tgtcgcatgg cctttcgcta cttgagccgc
    47281 caaaaggatc aaggacgaga gattgcggag aaaattgcat tggctagtca gtttgcgcag
    47341 gctgatcctt accgagctgc tactcataat aaaggaattt ttaatggtat tgatgcgatt
    47401 ttgattgcca ctggtaatga ctggcgtgcc atcgaagctg gggcccatgc ctttgccagt
    47461 cgagatggac gctatcaagg tcttagctgc tggacgctgg accttgaaag agaagaattg
    47521 gtcggtgaga tgaccctgcc catgcctgta gcgactaagg gtggctctat cggcctcaac
    47581 ccacgtgtag ctctcagtca tgatctacta ggaaatcctt ctgccagaga attagcccag
    47641 attatcgtgt ccatcggtct tgctcaaaat tttgcagccc tcaaagcctt ggtaagtacg
    47701 ggcatccagc aaggccacat gaaactacag gccaaatccc tagctctcct agctggggct
    47761 agtgaatctg aagttgctcc cctagtagag cgcctcatct cagataaaac ctttaaccta
    47821 gagacagccc agcgctatct cgaaaattta agatcataaa aactcagacg aatcggtctg
    47881 agttttcttg tgtttaaata ctttttcctg gtaatagcgt aactggtaag aagtaaccag
    47941 ttgtggcgac ttccttgcct tcaatctttt gcaagagaag atcaatagtg agacaagcaa
    48001 tctcttccaa aggttgcttg atagtagcca attgagggta gtaattttcg ataaagtagg
    48061 tcccatcata gccgatgacc ttgagctctt ttgggacaga aatgcccaat tcttgagcga
    48121 ttttaatgac cagaatagct gtcaaatcat ccgaagcaaa aatggcatct ggtttttccc
    48181 gggtcaagat attcttgatt tccatttctt ttctgacggg agaaaagtca ctggaaacat
    48241 tgataatagg agcttttggg agtacggatg caaaaccagc gtggcgcagt ccggttggcg
    48301 aattggaatt gtcattccct gtaatcatga tgatagactg ggcacctgtc ttgaccaagg
    48361 tttgggcagc aagaacccca ccagcatagt tgtcagagga gacaacaggg atgtctggcg
    48421 ataggtttcg gtcaaaggaa ataatcggcg ctgtcacacg attgtagtct tcgattccta
    48481 ggttgtgact accagaaatg atgccgtcca cctgattggc ttccaacatt tcgatgtatt
    48541 cacgttcctt ctcagaatca tgttcactgt tgcagatgat ggtcttgtaa ccatttttga
    48601 agagttggtg ttccaattta tcaatcaatt ctgcatagaa aacattggaa atattgggga
    48661 aaatcaagcc gattaactta gctgattttc cttgcagact acgagccagg ttgttgggtt
    48721 tatagcccaa ttctcgcatg gcttcattga ctttttggat ggttttctca gatagatacc
    48781 cttttttatt gataacccga gaaacggtag taggactgac gcctgcaagt ttggcgacat
    48841 cagttagttt tgcgaccata atctaattca tagtaagttc cagttgggtt tccagatttg
    48901 atcaggatac cattttggtc cgcatgtggg aagacacgac cagaaaatac tttttctcct
    48961 ttattgatga aaatttcaaa gacagagtta tcgatgaaga ttgtagcagt agtagcctga
    49021 ttctcgatag ggcaagagcg agttgtccca aattcttggg catactgttc tccagcctgg
    49081 ctacgatcca ctgtcacttg accgtttaca aggtcaaagt tgattgaaag tcccttacct
    49141 tctttatcag caagtaagac aatctcgctc tggctattag cttccaagtt gagttcaagt
    49201 tcgtaagtgt tcttggtttg ggaacggttt gagaaggctt cttcagaagc acgaaggtcc
    49261 ttaatagcag cgactggata ctggtagagc ttgtcgtctt tgatagtgag ttccttgacc
    49321 aaagagaagg ttccttggtg gtcaaaacgg tcagatgggt aagaaacatc tggcaaacca
    49381 agccagctaa ctgctagagc acgcccatca ggagcgttga aggcttgagt tgcataggct
    49441 tcgaaaccgt aatccatgtt ttgaagttga gacacatcta ccattttggc atttttaggg
    49501 tcaaaggaag ccccaatctt atacatattt ggaaagatat tatcgtagtc tagaactttc
    49561 ttatccaatc cttgtggaca gtagagaagg acaggctgtt cctctacaaa gaccagatta
    49621 ggacattcca tcatgtaggc agtacggtcg ttagcaaagt caaggtcgcc aactgcttgc
    49681 cagtttgtgt agtcgttatt gacagccttg tagagacgga cgaagccttt tttctccaag
    49741 tcctgtccac cgacgacagc atagtattga cctttaaagt taaaaatttg tggatcgcgg
    49801 aagtggtcag tagagtctgc tggctggtca atcaagatct tgtcaatctt tgtaatctta
    49861 ccctccttgt ccatcaaagc accgatttgg tatgggtgac ggatccagtt ttcatcgcga
    49921 acatttcctg tataaaatag gaataagtta tcgccaaatt gcatggcaga accagagtag
    49981 gcaccgtggc tatctaatgg agtatccggc aaaactttga ttccagtttc tttaaagtga
    50041 accaaatcat cactttctag ctgtgcccaa gatttcaaac cgtgggctgc accaaaagga
    50101 aaattctggt aaaagaggat ccacttgcca tcaaagtaag aaaagccatt tgggtcgttg
    50161 agaagtcctg tttttggctc aacatggtaa tgagtatgcc atggagattg tgccatattt
    50221 tcctttatat gttgaatttc ttcttgcgtc caatcttgat aaagtctgta acgacgctca
    50281 gttgtccatt ccattcattc ctccaaaaat cttatcactt ttaatagtaa ctgttttcga
    50341 taaaaaatgc aagcctttta tgttaaaaaa gaggaaaaac tatcaaacga ttatcataaa
    50401 ataaatacag gaaatcaatc aaatttttac gaaaatgtga aagataatga aataaaagac
    50461 tttttaatca aggtttcaaa cttatttttc aaggaatccc tgatgaaaca gtcaaaaaca
    50521 atcaatctaa agcttgcccg ctaagtggat agaatatttt ttctgcaaaa cgcttgacat
    50581 atttttgaaa catgataaaa taatagtcgt aagggcgaat aaaatcgctt tcaaacaaga
    50641 acaaaatgtt atataaggag atttttgcaa atgaacaatc aggaaattgc aaaaaaagtc
    50701 atcgatgcct tgggcggacg tgaaaatgtc aatagtgttg cccactgtgc gactcgtcta
    50761 cgtgtcatgg tcaaagatga agagaaaatc aataaagaag tgattgagaa cttggaaaaa
    50821 gttcaaggtg ctttctttaa ctcagggcaa taccaaatta tctttggtac aggtacagtt
    50881 aacaaaatgt acgatgaagt tgttgtactt ggcttaccaa catcatctaa ggatgacatg
    50941 aaagcagaag ttgctaaaca agggaactgg ttccaacgtg ctatccgtac tttcggtgat
    51001 gttttcgttc caatcatccc agttatcgta gcgacaggtc tcttcatggg tgtgcgtggt
    51061 cttttcaacg ctcttgaaat gccacttcca ggtgactttg caacttacac acaaatcttg
    51121 acagatacag ccttcatcat cttgccaggt ttggttgtgt ggtcaacctt ccgtgtattt
    51181 ggtggaaatc ctgccgttgg tatcgttctt ggtatgatgc ttgtctctgg ctcacttcca
    51241 aacgcttggg cagttgctca aggtggtgaa gtaacagcga tgaacttctt tggtttcatc
    51301 cctgttgttg gtttgcaagg ttccgttctt ccagccttca tcatcggggt tgtcggagct
    51361 aaatttgaaa aagctgtccg caaggttgtt ccagatgtca ttgacctctt ggtaacacca
    51421 ttcgtgacac ttttggtcat gtctatcctt ggactctttg tcattggacc agttttccac
    51481 gttgttgaaa actacatcct tattgctaca aaagcgattc ttagcatgcc atttggtctt
    51541 ggtggtttct tgattggtgg ggttcaccaa ttgatcgtcg tgtcaggtgt gcaccacatc
    51601 ttcaacttgc ttgaagtgca attacttgct gctgaccatg ctaacccatt caacgctatc
    51661 atcacagctg ctatgacagc tcaaggtgct gctactgttg cggttggtgt taaaacaaaa
    51721 aatccaaaac tgaaaacact tgctttcccg gctgctcttt ctgccttcct aggtattaca
    51781 gagcctgcta tcttcggggt gaacttgcgc ttccgtaaac cattcttcct ttcattgatt
    51841 gctggtgcaa tcggtggtgg attggcttct atccttggac ttgctggtac tggtaatggt
    51901 atcaccatca tccctggtac aatgctttat gttggtaacg gacaacttcc acaatacctt
    51961 cttatggtag ctgtatcatt tgcccttggt tttgctctta cttacatgtt tggttacgaa
    52021 gatgaagtag acgcaactgc agctgcaaaa caagctgaag tggctgaaga aaaagaagaa
    52081 gttgcgccag cagctcttca aaatgaaaca cttgtaactc ctatcgttgg tgatgttgtc
    52141 gctcttgctg atgtcaatga cccagtcttc tcaagtggag ctatgggaca aggtatcgct
    52201 gtgaaaccaa gccaaggcgt ggtctatgca ccagctgatg ctgaagtttc aattgccttt
    52261 ccaacagggc acgcttttgg tttgaaaaca agaaatggtg ctgaagtttt gattcacgtt
    52321 ggtattgaca ctgtatctat gaacggtgac ggttttgaag caaaagttgc tcaaggtaat
    52381 aaggtgaaag ctggcgatgt tcttggaaca tttgactcaa acaaaatcgc tgcagctgga
    52441 tttgatgata caacaatggt tatcgttaca aatacagctg actacgcttc agtagctcca
    52501 gtcgcaacag gttcagttgc gaaggggaat gctgtgatcg aagtgaaaat ctaatcaatc
    52561 ctctctaatg tgaaaacgaa caaatgacat gtttgttcgt ttttattaga tagtaagatt
    52621 tacagaggaa aatctaaaaa atagagacat ttagactttc gaagtatgct ataataaaga
    52681 aaataaaaac aagaggttta tcatgacaaa attatatgga agcttggaag cgggcggtac
    52741 aaagtttgtc tgtgctgtcg gtgatgaaaa ctttaacgtt gtagaaaaaa cacaatttcc
    52801 aacaacaact ccaatcgaaa caatcgataa aaccattgag ttcttctcaa aattcgataa
    52861 ccttgctggt cttgcagttg gttcatttgg gccgattgat attgacaaaa actcaaaaac
    52921 ttatggcttt atcacgacga ctccaaaacc aaactgggca aatgtggact tgcttggtgc
    52981 ccttcgtcgc gccctaaacg tgccaatgta cttcacaaca gacgtaaaca gctctgctta
    53041 cggtgaaatg gttgcccgta acaatgctgg tggtcgtatc gaaaacttgg tttactacac
    53101 aatcggtaca ggtatcggtg caggcgtcat ccaacgtggt gagtttatcg gtggtgtggg
    53161 tcaccctgaa atgggtcatt attatgttgc tagacaccca atggatattg aaaaagagtt
    53221 taagggtgtt tgtcctttcc ataagggatg tctagaaggt tatgcagctg gtccaagttt
    53281 ggaagctcgt acaggtgtac gtggggaaac tattgaactc aacaaccctg tttgggatgt
    53341 tcaagcctac tatatcgctc aagctgcggt taatgcgaca gtgactttcc gcccagacgt
    53401 gattgtcttt ggtggagggg tcatggctca acaacatatg ctggaccgtg tccgtgagaa
    53461 atttacatct cttcttaatg gttacctacc agtaccagat gtgcgtgact atatcgtgac
    53521 gccagcagtc gcaggaaatg gttctgccac acttgggaac tttgttcttg caaaagaagt
    53581 ttcaaaataa agcacaaaat ccgcttggga aaccaaacgg attttgtggt tgaaaacaat
    53641 atttttgagc ctttccttaa gtgattacgg acggtagcga ctttcttcga aattccatac
    53701 ctaaactttg agcctagtgt ctcaaagttt ccgaatacct gaaaccatta gatttcaggt
    53761 gtttctatca cggcggaaag gctaggtaag tcctcgcctc actatcgaaa aatatgcatg
    53821 atttccatac caaagtatat ttagtatcaa gctatagtta atctacgctt taaaaatcca
    53881 cttgggaaac caaacggatt ttttacgtgt caaagcattt gccagaaaaa gtcaataata
    53941 taggtcagac cgtaggtata aaccacgagg gtaaagggtt tggtcagaat gatgatggtc
    54001 atgtagcgct tgaaactcat cttggtcagg gcagccagca tacagagaaa gtcagctggg
    54061 ctaatgggcc aaatcatcat aaaaataaag aagcggtcaa aacgattgcc cttatctagc
    54121 cagccgatgt acttgtcgta ggtgcgcttg ctgacgacag actggacaaa ggcagctccg
    54181 tataggcgca ctagataaaa gataatggca cagccaatca cgatgccgat atagttgtag
    54241 atagtcccga tgatgtgccc gtagataaag accccagcca ccgaggtcaa ggcccctgga
    54301 atgataggga cgacagtctg taaaatctgt aaaaagataa agagaggtgg accccagatg
    54361 cctgcctgct ggataaaggc agagagggtt tccttggatt gtaaaatccc agcctgataa
    54421 gcccaaatac agaaaatcaa actcccaacc ccaccgacaa tcgatgagat attgataact
    54481 cgctgcagaa ggggagaaac agctttcatt tgtttatcct gtgacatgta aactcctcat
    54541 agatagtata tttctactat accatatttt ggaggagaaa gggggaatga gtcttttttg
    54601 ataaggaata gaaagtaaat agcccttcga gacttagaat aggtctgtca actaaaggtt
    54661 atatgcattc taggtttcga ataatcgcaa ttccataaat ttaaaagcat tctaagtttc
    54721 gaatagctta tctgagataa ttttgaggca ttcgcgcttt cgaatagtca tttttcctaa
    54781 agtttagatg tattctgaag ctagaaagac taaaatctaa aagtagtaag agtctctctc
    54841 tgatggacgt aatttatggc tagtatgaat cctttgaatt gttagttaat tttaatatta
    54901 atcagttctg aaataattac taaatatagt tagatggtga attaattatt gctaaatttc
    54961 aagttcaagt tagtcatcca gaagtcttct ctgggggact tgtagttcaa gcatttttta
    55021 ggatagttgt taatccactt ttcgatgaat gcgacttcct ttgtagtcgt tttcttagtt
    55081 ccctgaggta accatctatg aatgagtctg ttgtgatttt cattagatcc tatagtgatg
    55141 tgcataatag atatagcaga ttgaaactag aatagtatac atctacttct aaaacattgt
    55201 tagaaatcaa tttgactgtc ctgatcaatt tgtcctgttt ttatttcatt ttactatata
    55261 atccttagaa aacatatggg acaagcggtt gaattctgtt ccgtccatta gtagataaag
    55321 gattactcct tcttgaaatg acagatgaac ttgtttctta taaaaatgtt gtctgaaact
    55381 attcgccttt ttccagaagt tttagaggaa gaaaacttta tgaggaaaaa ggagttactc
    55441 aaataacaat tcaggattaa aaatagacag ttgaggagcg gaaggtataa attaagtttg
    55501 ctactgtata atggatttat cactaatact cttcgaaaat ctcttcaaac cacgtcagct
    55561 tcgccttgcc gtacgtatag ttactgactt cgtcagttct atccacaacc tcaaaacagt
    55621 gttttgagct gacttcgtca gttttatctg caacctcaaa gctgtacttt gagcagccta
    55681 cggctagctt tctagtttgc tctttgcttt tcattgagta taaaagtgct ccaggccata
    55741 ttttacacag caatagtctt ctaaaaatgg acaaaaaaca ttgtaaaggc tatcaaaaag
    55801 gagtataatg agtgcaagaa atttcggagg tgaaagatgc tagaagtaag aagtctagag
    55861 aaaagttttg gatccaagca agttttgttt ggtattgact ttcaagcgcg accaggtcgt
    55921 attttgggac tagtcggaaa aaatggtgct ggaaaaacaa cgattttcca tagtattttg
    55981 aaattcctag aatatcaggg agaaatcggt ctggatggtc aggatattcg tcaggagacc
    56041 tatgctcgga ttggttatct gcctgaagaa cgcagtctca tgcctaaatt gacagttctt
    56101 gaacaagttc gctacttggc gactctaaaa ggcatggatg ccaaagaagt caaagaaaaa
    56161 ctccctcaat ggatgaagag gttggaagtg aaaggaaagc tgacagataa aatcaagagt
    56221 ctgtcaaaag gaaatcagca gaagattcag ctcattatta ctctgattca tgaaccagac
    56281 ctgattatct tggatgagcc ttttagtgga ttggacccag ttaatacaga attgctcaaa
    56341 caagtcattt ttcaggaaaa agagcgcgga gcaaccatta tcttttctga ccatgtcatg
    56401 accaatgttg aggaactttg tgacgatatt ctgatgatcc gagatggccg tgtggtcttg
    56461 cacggaccag ttcaggatgt ccgcaatcaa tacgggaaaa cgcgtctctt tgtttcaagt
    56521 gaacgaagca aggaagaatt ggaaaatctt cctcatgtca aacaggtgag cttgaccaaa
    56581 caaggcagtt ggaaattgat tttggaggat gagagcgctg gaagggaact cttcccaatc
    56641 ttgactcaag gtcaatatat cgcaacattt gaccaacaag cgccaactat cgatgaaatc
    56701 tttaaactag aatcaggagt ggaagtatga gaaatatgtg ggttgtaatc aaggaaacct
    56761 atcttcgaca tgtcgagtca tggagtttct tctttatggt gatttcgccg ttcctctttt
    56821 taggaatctc tgtaggaatt gggcatctcc aaggttcttc tatggctaaa aataataaag
    56881 tggcagtagt gacaacagtg ccatctgtag cagaaggact gaagaatgta aatggtgtta
    56941 acttcgacta taaagatgaa gcaagtgcca aagaagcaat taaagaagaa aaattaaaag
    57001 gttatttgac cattgatcaa gaagatagtg ttctaaaggc agtttatcat ggcgaaacat
    57061 cgcttgaaaa tggaattaaa tttgaggtta caggtacact caatgaactg caaaatcagc
    57121 ttaatcgttc aactgcttcc ttgtctcaag agcaggaaaa acgcttagcg cagacaattc
    57181 aattcacaga aaagattgat gaagccaagg aaaataaaaa gtttattcaa acaattgcag
    57241 caggtgcctt aggattcctt ctttatatga ttctgattac ctatgcgggt gtaacagctc
    57301 aggaagttgc cagtgaaaaa ggcaccaaaa ttatggaagt cgtcttttct agcataaggg
    57361 caagtcacta tttctatgcg cggatgatgg ctctgtttct agtgatttta acgcatattg
    57421 ggatctatgt tgtaggtggt ctggctgccg ttttgctctt taaagatttg ccattcttgg
    57481 ctcagtctgg tattttggat cacttgggag atgctatctc actgaatacc ttgctcttta
    57541 ttttgatcag tcttttcatg tacgtagtct tggcagcctt cctaggatct atggtttctc
    57601 gtcctgaaga ctcagggaaa gccttgtcgc ctttgatgat tttgattatg ggtggttttt
    57661 ttggagtgac agctctaggt gcagctggtg acaatctcct cttgaagatt ggttcttata
    57721 ttccctttat ttcgaccttc tttatgccgt ttcgaacgat taatggctat gcggagggag
    57781 cggaagcatg gatttcactt gctattacag tgatttttgc ggtggtagca acaggattta
    57841 tcggacgcat gtatgctagt ctcgttcttc aaacggatga tttagggatt tggaaaacct
    57901 ttaaacgtgc cttatcttat aaatagaaga gccttgcgaa agcgaggttt ttaaaggtga
    57961 aaagggtgga atcacgaacc taattatgta cacattatgt aaacaggttg cttgaaaact
    58021 caattgtata gtgaactgaa tctggaatag gataatatta cttctaaaac attcttataa
    58081 attgatttga attccaaaat cccatcgttc cgttcttatt tcattttgcg atatagtgaa
    58141 aggaaataag tcagctcaca aaaaacgcat aatatcaagg atttttaaca cttgatacta
    58201 tgcgttttct aattgtaaag actttttgcc tggtctcttt tgttctatga gtatgttaca
    58261 tatctaggta aaaattattt aaagcaaatt aaccttattt ctcaagatgt agtaggttcc
    58321 gagataaaag atagctatga atatgagttc ttcaacaatg gctatacctg ctcccatata
    58381 gaaatggtca ttgagtccta ccagtgaatt gacatagaaa ttagaactaa gattgaagaa
    58441 aagttcaata aatccaatga cgatttggat accaatgtag actgcaacag cgagtgctgt
    58501 acggtattca ttgaaaagct gtccaatgga aatagccagg tagatgcaga ggattcctga
    58561 aatagtattt agtaggaagg atatacctgt aagaaagatc tgagggagat gtgtttctac
    58621 aaatgtaatc acataagaaa gaggaatcca ttctggagct gttaaagcca gaataataac
    58681 agcacttaga gccaatacag cggtgctaat caatgaccag ataaaggcac cgattagttt
    58741 ggctgtgatg atatggtgtt cagaaactgg caaggtcaaa gtcagatagc cttgtcggtc
    58801 gtagacacta cctttgaagc gtttaataat caagaaaatg gttgaaatcg caagtgtaag
    58861 catcaagcca ccaaagactg tggctagaaa aagtagcata gtagcctgac tttcttggta
    58921 aggtagattt ttaaagcctt gtgtctgtat tccgatgagg gcagaaagga ctagcacggc
    58981 tgcgtagagg gctaaatacc acttgttaac atttttaaat tcgtagcgaa ctaaattcca
    59041 aaacataaat aatctccttt gcttaggcct taaattcctg acggaagagt tggtcaatgg
    59101 attcacctga ctcgtagcga atatcatcta catttccttg acggacgact tttccgtctt
    59161 ttaggaagac aatttcatcc aagattggct cgatatcaga aatcaagtgg gtagaaatca
    59221 aaacggtaga agttggtgag tagttgttga taatggtatt gaggatataa gcacgggctg
    59281 ctggatccac cccaccaatg ggttcgtcca aaacatagag acgagcatca cggctcataa
    59341 ccaaaatcag ttgaaccttt tctttgtttc cttttgatag tttcttgaga cgactatttt
    59401 catcaatgcc caggtctgca agtagatgat gagcgcgttc aagattgaaa tctttataga
    59461 aggtcttgaa gtaggttagg gcttctttga ccttcatttg ctcattgaga taggtcgtat
    59521 caggcaaata agctacaacg gccttggttg ctgggcttgg gtccatgtcg ttgatgagga
    59581 cacgtccttg atctggttgt aagaggccat taattagttt aatcagggtt gtttttcctg
    59641 agccgtttgg cccaagaagg ccgacaattt ttccagctgg aatgtcaaga gaaacatttt
    59701 caagggctgg tgttgctcca tatgatttgg atacattttc aaatgctagt aatgacatag
    59761 gcttaaactc ctttaatata atcactgact acgcctggta gttcttcttt ttcatagcca
    59821 aaatgggtca tggaggaaac gaagtgttcc aattcttctt ctgataattg tttgcgtgac
    59881 tgagcgatta gctccttatc cttagtcaca aatcgtccag ttgttcgctt gctgtagaca
    59941 aatccttctc gttcaaggtc tgataaggct ctttggatgg tattgggatt gacaccagcc
    60001 tcgctagcta gctccctcac ggttggaagt tgttgattgg gttccagtgt atgggaaaca
    60061 atctgaagct tgattttctc cataatctgt aaatagatgg gttttttgtt gtcaaatgtc
    60121 caggacatct tagtctcctt tctcttattc ttttgtctta attaaataat acaacaaaac
    60181 aaaaaacttg tcaagcaaaa agaagaattg ttttgggaat cgcttaaaaa atggtataat
    60241 gaaaagaaaa cgataaggag ggaaaggatg cgttgtccaa aatgtggggc taccaagtca
    60301 agtgttatcg atagtcgcca agcagaagaa gggaacacca ttcgtagaag acgagagtgc
    60361 gacgagtgcc aacaccgttt tacaacctac gaacgagtag aagaaagaac cttagtggtt
    60421 gttaaaaaag atggcacacg ggaacaattc tccagagata aaatctttaa tgggattatc
    60481 cgctcagccc agaaacgtcc tgtgtcaagt gatgaaatca acatggtagt caatcgtatc
    60541 gaacagaaac tccgtggtcg aaatgaaaat gaaattcaaa gtgaggacat tggttcactc
    60601 gtcatggagg agttggctga attggacgag attacctatg tacgttttgc tagtgtctat
    60661 cgtagtttta aggatgtcag tgagttagag agcttgctcc aacaaatcac ccagtcctct
    60721 aaaaagaaaa aggaaagata aatgaagcca attgaccgtt tttcttatct aaagaataat
    60781 cgggtgtcgc aagatacctc atctctggta cagtgctacc tcccgattat cggtcaggag
    60841 gcactgagcc tttatcttta tacaatcagt ttttgggata atggtagaaa ggaatatctt
    60901 ttttcaagta tcctcaatca tctcaacttt gggatggata gactgataaa atcattgaaa
    60961 atcttatctg cttttaatct cttgaccctc tatcaaaagg gggatgttta tcagctagcc
    61021 ctccatgctc ctctatctag tcaagacttc ttggagcatc ctgtttatcg cagactctta
    61081 gagaaaaaga ttggcgactc tgctgtggag gatttgaaag ttgaaagtgc tgatggtgaa
    61141 gaaatacctg tctcactcaa tcaagtcttt ccagaattgg cagaactagg cagtcaagaa
    61201 gaccttggtc tcaagaagaa agtggccaat gattttgact tggatcattt tcgtcagctg
    61261 atggctcgag atggacttcg ttttgcggat gagcagtctg atgtcttgaa cttgtttgct
    61321 attgctgagg agaagaagtg gacttggttt gagacctatc aattggccaa gtcaacagct
    61381 gtttcccagg ttatttcaac caaacgcatg cgggaaaaaa ttgctcaaaa accagtttcc
    61441 tcggacttta gtcctaagga aacaaccatt atcaaggaag ctaaaagtaa aactgccctg
    61501 cagttcttgg cagaaatcaa gcaaacacgc aagggaacca ctacccaaac agaaagagaa
    61561 ctcttgcaac agatggctgg cttgggcttg ctggacgaag tcatcaatat cattctttta
    61621 ttgaccttta ataaggtcga ttcggcaaat atcaatgaga aatatgccat gaaggtagcc
    61681 aatgactatg cctatcaaaa gattcattcg gcagaagagg cagtcttgcg catccgtgag
    61741 cgaggacaga aagcaaaaac acaaaaacag aatcagactg ccccagtaaa aaccaatgtt
    61801 cctaaatgga gtaatcctga atataagaat gaaaccagcg aggaaactcg tctggaacta
    61861 gaacgtaaga agcaagaact attagctcga ttagaaaaag gaggagatta gatggaaagt
    61921 gtcggagacg tactcaaacg tcaacccagc cgtttttatt atcaagattt ggtccagaaa
    61981 atcatgaagg accctgatgt tgcggctttt atccagcaag aatccttgac tccagaggaa
    62041 ttaaatcgca gtatctccaa gtttaatcag tacatcaccg agcgtgacaa gtttctccgt
    62101 ggggatacgg attatattgc caaaggctac aagccgattt tggttaagaa tcatggctat
    62161 gcagatgttt catatgaaga aactcctgag ctaatcgcgg ctgaaaaaga agcggctatt
    62221 aagaaccgtc tcaagttaat caatctacca gccagtctca agaaagctag tttggctcaa
    62281 gttgacttgg atgatttggg gcgcttacca gtttttgaaa agctactagc cttcgtggag
    62341 caatatccag ctattcgaaa aggtctttac ttatatggag actttggtgt gggtaaaagt
    62401 ttcatggtgg cggccttagc tcatgattta tcagaaaaac gtggtgtttc atcaactctc
    62461 ctccactatc ctagctttgt cattgatgtc aaaaatgcta tcagtgatgg caatgttaag
    62521 accttggtgg atgagattaa gctgtctgag gtcctgattt tagatgatat tggcgccgag
    62581 caatccaccg cttgggtgcg tgatgaaatc ctgcaggtca ttctccaata tcggatgcag
    62641 gaaaatttac cgaccttttt cacatccaac ttcaactttg aagatttgga gaagcatttt
    62701 gcgaaagtga aacatggaaa tgacgaaacc tgggaagcca gacgggtcat ggaacgcatc
    62761 cgttatttgg ctgaggagac tcgtttagaa ggagtaaacc gtcgatgaca gaaaccatta
    62821 aattgatgaa ggctcatact tcagtgcgca ggtttaaaga gcaagaaatt ccccaagtag
    62881 acttaaatga gattttgaca gcagcccaga tggcatcatc ttggaagaat ttccaatcct
    62941 actctgtgat tgtggtacga agtcaagaga agaaagatgc cttgtatgaa ttggtacctc
    63001 aagaagccat tcgccagtct gctgttttcc ttctctttgt cggagatttg aaccgagcag
    63061 aaaagggagc cagacttcat accgacacct tccaacccca aggtgtggaa ggtctcttga
    63121 ttagttcggt cgatgcagct cttgctggac aaaacgcctt gttggcagct gaaagcttgg
    63181 gctatggtgg tgtgattatc ggtttggttc gatacaagtc tgaagaagtg gcagagctct
    63241 ttaacctacc tgactacacc tattctgtct ttgggatggc actgggtgtg ccaaatcaac
    63301 atcatgatat gaaaccgaga ctgccactag agaatgttgt ctttgaggaa gaataccaag
    63361 aacagtcaac tgaggcaatc caagcttatg accgtgttca ggctgactat gctggggcgc
    63421 gtgcgaccac aagctggagt cagcgcctag cagaacagtt tggtcaagct gaaccaagct
    63481 caactagaaa aaatcttgaa cagaagaaat tattgtagaa agtgagaaat tatggcccta
    63541 ccaactattg ccattgtagg acgtcccaat gttgggaaat caaccctatt taatcggatc
    63601 gctggtgagc gaatctccat tgtagaagat gtcgaaggag tgacacgtga ccgtatttat
    63661 gcaacgggtg agtggctcaa tcgttctttt agcatgattg atacaggagg aattgatgat
    63721 gtcgatgctc ctttcatgga acaaatcaag caccaggcag aaattgccat ggaagaagca
    63781 gatgttatcg tttttgtcgt gtctggtaag gaaggaatta ctgatgcaga cgaatacgta
    63841 gctcgtaagc tttataagac ccacaaacca gttatcctcg cagtcaacaa ggtggacaac
    63901 cctgagatga gaaatgatat ctatgatttc tatgctctcg gtttgggtga accactgcct
    63961 atctcatctg tccatggtat cggtacaggg gatgtactag atgcgattgt ggaaaacctt
    64021 ccaaatgaat atgaagaaga aaatccagat gtcattaagt ttagcttgat tggtcgtcct
    64081 aacgttggaa aatcaagctt gattaatgct atcttgggag aagaccgtgt cattgccagt
    64141 cctgttgctg gaacaactcg tgacgctatt gatacccact ttacagatac agatggtcaa
    64201 gagtttacca tgattgatac ggctggtatg cgtaagtctg gtaaggttta tgaaaatact
    64261 gagaagtact ctgtcatgcg tgccatgcgt gctattgacc gttcagatgt ggtcttaatg
    64321 gtcatcaatg cggaagaggg gattcgtgaa tacgacaagc gtatcgctgg atttgctcat
    64381 gaagctggta aagggatgat tatcgtggtc aacaagtggg atacgcttga aaaagataac
    64441 cacactatga aaaactggga agaagatatc cgtgagcagt tccaatacct gccttacgca
    64501 ccgattatct ttgtatcagc tttaaccaag caacgtctcc acaaacttcc tgagatgatt
    64561 aagcaaatca gcgaaagtca aaatacacgt attccatcag ctgtcttgaa cgatgtcatc
    64621 atggatgcca ttgccatcaa cccaacaccg acagacaaag gaaaacgtct caagattttc
    64681 tatgcgaccc aagtggcaac caaaccacca acctttgtca tctttgtcaa tgaagaagaa
    64741 ctcatgcact tttcttacct gcgtttcttg gaaaatcaaa tccgcaaggc ctttgttttt
    64801 gagggaacac cgattcatct catcgcaaga aaacgcaaat aaaaaagtag aatctggaat
    64861 gacagttccg gatttttttg atataataaa ataatagaaa acgctatcaa aagaaggggg
    64921 atgtcggtga tggaacattt gtttaaattc ttacttttag caccgtactt ttattttgat
    64981 aactggattg aaaaggccaa cagaaatagt aagttttttc caatttttta ttatttttac
    65041 tggttttaca tccccttcta ttctcttttt agccttgctt ggacagttgt ttcagttctg
    65101 tttttcaata ccgtcttgag aaatgtgaca gatatcaagt tatggggcat ttggtttctt
    65161 tttattctgc tagctattgg tatgaattgg ttaacttatt cctgtttcaa agaaatgttt
    65221 cgcttgagac aggaactagg gaagtctaag ggtggaaggc attgatttat atcggtttct
    65281 atttgtagga ggtggcttat ggtacctcta aaatcattta ttacacgcta ttccaaggtt
    65341 tatattggta ataacattta atagaacgaa actaaagaaa acaatttaaa aaaggaggct
    65401 tgtgatggaa cacttgttta aaatgataat cttattaccc tgtttttact ttttcagctg
    65461 gattgacaag gataatagag aaagtaaatt tttcccaatt ttttactatt tttactggat
    65521 ttacatcacc ctctatgctc tttttagcct tgcttggaca gttttttcag ttctgttttt
    65581 caatatcgtc ttgagaaatt tgacagatat caagttatgg ggtatttggc tattattact
    65641 acttatcgct tttgctagtg attggttagc ctatgtcttt ttcaaaaaaa tgattcgctt
    65701 gaggcgggaa ctagggaaat ctaaaggtgt gcataaagga aggtgtagga actaaaaaat
    65761 gactgtatct atgatttgtt tatggagcta tagatacagt catttttatt ttgattatga
    65821 aacttgagag aaatattcat cttgtatagt ggattgaata tggaataata caatacaact
    65881 tataaaacat tggtataaaa tgctttagat cccctaattg attcgttcac attctattac
    65941 aatctactat aataaaatga tgagagttat tacaaattat aggcttgaaa aatcattaat
    66001 ttctttttcg agtattttaa ctaatgcctc ttctttggtt agtcgtaata aagttattcc
    66061 tttatcaatc aaatcggagt tatgttgtag tattcccaag cgtacttgag agaatccaag
    66121 aatatcgtat atttttaatt cttctgctaa taccaaaagt tgtagggtga ttgtttcaca
    66181 ttctttgaat aaatgatgtt gaaaatatac agtggagaga ttggctaaaa aagatgataa
    66241 aaatgctttt gtttctcgga agtatttata tttctcgatg gttttcataa ttctatcaat
    66301 aagaagggga agattttcag aaggaaagaa aaagagaatg gttccaagca atttcaaatc
    66361 actaatgtac catgtatcca taggttcaag atagtcccaa atttcttcat acaaatcttt
    66421 caagacgtgg ttgtttttga atcctttagt tcgtaactct gtgacaattt ttgtatgacg
    66481 atagatattt tgaataggaa catcgtgatg tgtcttaaga tatttttgac atttctcagt
    66541 gagttcaacc atttttctag tatcttgaaa agtagacgga ttttggctct ctacaataat
    66601 atctcgcctt ttactaggat ggtattcgtt gcatatatac ttgaattctg ccaagctcat
    66661 atcaatttgt tcaagaagaa ataccatgtt ttcaaaactg ggaataactt taccgtgttc
    66721 aatatttgtt agagttgttc gatgtatgac ttgtccacat acatcttgtt gggtcaatcc
    66781 ttttgacttt cgaatttctt taaaaatttg tccataatcc catctcatat tgttcctcct
    66841 aggtaaatgt gaatattttc tacatttata aaaaacgtag aaaaaggtgg tattattata
    66901 tcaaaaagga gggaaaaagt catgggcttt aaaaaatatt tgaagaattt accgaaaaac
    66961 tctggatttt tgatttggag ttggattcaa cttatctggt ttgaaacatg gttttgggga
    67021 taaagaaatt agagtctata tataataagt aaaggaggaa tttgtatgat ataccatcgt
    67081 ttagaataag tctatattta aaatagaagt tataaggaat cttcttgaat aaaaaatgaa
    67141 aggaaacaga aaaaatgaaa attaagaaat tattgaaaat ggttattcct gttttaatga
    67201 taagtgctgt tggaactact ttcgtagaag caaatcagat aggtgctttt agtaattttg
    67261 ttattactac cagttataag agaacaggtt atttgactaa agaaaatgaa ggtgcggaat
    67321 atatcatgaa cttaaatcct tgtagaaatt tacatcccat gactgttaag catcgtatag
    67381 taaattctaa tggagaagct cgtagtggag aatcgttaac aacctgtggt actcgttcaa
    67441 ctcatggtaa ttgggcaacg gttggctatg tttatgcagc agatatggca agacaaaatt
    67501 ggtgggattt atcagctgcc atttcaggta gttggtcacc aaattaattc gtaaagtagg
    67561 tataatttat gaagattcct ctcttaactt tggcaaggca taaatttgtt tatgtcttgc
    67621 ttactttgct ttttcttgct ttggtttatc gtgacgtttt gatgacttat ttcttttttg
    67681 atattcatgc gcccgatcta gctaaattcg atggacaagc aattaaaaat gacttattaa
    67741 aatcagcatt agattttcgt attctccagt tcaatctagg tttttatcaa tcatttatta
    67801 ttccaatcat cattgttttg ctaggttttc aatatattga gctgaaaaat aaagttttac
    67861 gattgagtat tggaagagaa gtgagctatc cagggttaaa aagaaagttg actttgcaag
    67921 ttgcaagtat cccttgtttg atatatttag tgactgtgct gacaattgca attataacct
    67981 atttccttgg gactttttct cctcttggat ggaattctct attttctgat ggaagtggtt
    68041 tacaaagact cctagatgga gagataaaaa gctatttgtt ctttacttgt gtcctgctaa
    68101 tcggtatttt catcaatgca atctattttt tacaaatagt tgattatgtg gggaatgtga
    68161 ctcgttcggc aatcacctat ttgatgtttc tttggcttgg ttctatgctg ctctatagtg
    68221 ccttgcctta ctatatggtt cctatgacga gtttgatgca agctagctat ggggatgtaa
    68281 gtttgatgaa actctttact ccttatatcc tttatattgt cccttacatg gtgcttgaaa
    68341 aatatgaaga taatgtttaa gaattttaac aatattttgc taaagagaaa gattgtttta
    68401 ctacttcgta tagttctgat gatgattttg ataaaccatc tattgtcaac agcggttcaa
    68461 aagcaggatg ctgttatctt tttcaagaga gaattgattt caattttttc ctataatgac
    68521 tattctgaag cgaatttaga aatccccaaa ctcttgttaa acctttcgct tttcatggta
    68581 ggatggctct ctgtcatttt acttgaaagt gatttggcag accattacca tcacttgatt
    68641 cgctatcaat caagctcctt tttcgattat acaaggaaac gattggttgt catttctaaa
    68701 ttttttactc aagatttgtt tgtctggttc cttggtttac ttccgctagg aattcatttc
    68761 aaaacagtcg cacttttctt tttacttgct cagttaatga tgttgtactt actactgtct
    68821 tatctgatag cactgattag tgcgggcgct ggtttttcct tttttctcta ttttttagta
    68881 tttgtgggac aagaatggat gatggatcat attgtaacag tgtatttact actcttaagt
    68941 ttattagtta tgttgattgt tagtcgcttg gaagagaaat ttaagaaagg ataaacgatg
    69001 agacttgaaa ttataaatgg acagaaaatt tatgggaaaa gacctatttt aaatcagttg
    69061 aatttggtgt ttcaatcagg aaaaatttat ggacttaaag gtgataatgg atctggcaag
    69121 acggttcttt taaaggtact tgctggctat attaagcttg acaaaggaaa agttcttcaa
    69181 gacgggaaag tctacgggat aaaaaatcat tatattcagg atgcaggaat tttaattgaa
    69241 aaagtcgagt ttttatctca tttatccctg agagaaaatt tggaactgtt aaggtatttt
    69301 tcatctaaag ttacggaaaa aagaattgcc tattggattc aatactatga tttacaggaa
    69361 tttgaagacg ttgaataccg tcatttatcc ttgggaacaa agcaaaaaat ggccttgatt
    69421 caagccttta tttcctctcc ttctatactc tttctcgatg aacctatgaa tgctttggat
    69481 gagaagagtg tgaggttaac caaacaggtc attttatctt acctgaaaaa agaaaatggt
    69541 ctggttatcc tgacgtcgca catatcggaa gatatttcag acctttgtac agatgtatta
    69601 gttgtcgaaa atggacatat acaaatgtaa aggatataca atcctaggag atggcttatg
    69661 gcacatctaa aatcatttat tacacgctat tccaaggttt atattggttt agttctgctg
    69721 atctggctgt ctttcttctt tatcccttgg gatagagcga ttctgggggt aaggattgac
    69781 atcttcatca tacagaaaat cttgctagct tttggaattc tgtccattct catggccttg
    69841 ctgtccaaga aagtcagtct ctttgttttt ggactgattt gctgtctttc tctttggatt
    69901 aacttattta tcacatttgc cattttgccg atttttggca attaaacagt cataaaagtc
    69961 ggagaggtta gcttgaaaac taacctcttt ttccttttca aaatggggat tcttccttga
    70021 aaataatcag taattgtgct aaaattaaag gaacattcta aaatattcgg aatttaaagt
    70081 aaggaaaaac atggctaata ttttaaaaac aattatcgaa aatgataaag gagaaatccg
    70141 tcgtctggaa aagatggctg acaaggtttt caaatacgaa gaccaaatgg ctgctttgac
    70201 tgacgaccaa ctaaaagcaa aaacagttga atttaaggaa cgttatcaaa atggagaatc
    70261 actggattca ttgctttacg aagcatttgc ggttgtccgt gaaggtgcca aacgtgtcct
    70321 aggtctcttc ccttataagg ttcaggtcat gggggggatt gttcttcacc atggtgacgt
    70381 gccagagatg cgtacagggg aagggaaaac cttaactgcg accatgccgg tatacctcaa
    70441 tgccctttca ggtaaagggg ttcacgtagt tacggttaat gaatacctgt cagaacgtga
    70501 cgcgactgag atgggtgaat tgtactcttg gcttggtttg tcagtaggga ttaacttggc
    70561 taccaaatct ccaatggaga aaaaagaagc ctatgagtgt gatattactt actcaactaa
    70621 ctcagaaatc ggatttgact accttcgtga caacatggtc gttcgcgctg aaaacatggt
    70681 acaacgtccg cttaactatg ccttggtcga tgaggttgac tctatcttga ttgacgaggc
    70741 tcgtacacct ttgattgtat caggtgccaa tgcggttgaa accagtcagt tgtatcacat
    70801 ggcagaccac tatgtaaaat ctttgaacaa agatgactac atcatcgatg tgcagtctaa
    70861 gactattggt ttgtctgatt cagggattga cagggctgaa agctacttca aacttgaaaa
    70921 cctctatgac atcgaaaacg tggctttgac ccactttatc gataacgccc ttcgtgccaa
    70981 ctacatcatg cttctcgata ttgactatgt ggtgagcgaa gagcaagaaa tcttgattgt
    71041 cgaccaattt acaggtcgta ccatggaagg tcgtcgttat tctgatggat tgcaccaagc
    71101 tattgaagcc aaagaaggtg tgccaatcca ggatgaaacc aagacatctg cctcaatcac
    71161 gtaccaaaac cttttccgta tgtacaaaaa attgtctggt atgacgggta caggtaagac
    71221 tgaggaagaa gaatttcgtg aaatctacaa cattcgtgtt attccaatcc caacaaaccg
    71281 tcctgttcaa cgtattgacc actcagacct tctttatgca agtatcgaat ctaagtttaa
    71341 agcggttgtc gaagacgtta aggctcgtta ccaaaagggt caacctgtct tggttggtac
    71401 agtagcggtt gaaactagtg actacatttc taagaaattg gttgcagctg gtgttcctca
    71461 cgaagtcttg aatgccaaaa accactatag agaagcccaa atcatcatga atgctggtca
    71521 acgtggtgcc gttaccatcg caaccaacat ggcgggtcgt ggtaccgaca tcaagcttgg
    71581 tgaaggtgtt cgtgaacttg gaggactttg tgttattggt acagaacgtc atgaaagtcg
    71641 tcgtatcgat aaccagcttc gtggacgttc aggtcgtcaa ggagatccag gtgagtcaca
    71701 attctaccta tctcttgaag atgatttgat gaaacgtttt ggttctgaac gcttgaaggg
    71761 aatctttgaa cgtctcaaca tgtctgaaga ggccattgag tctcgcatgt tgacgcgtca
    71821 ggttgaagca gctcagaaac gtgtcgaagg aaataactac gatacccgta aacaagtcct
    71881 tcaatacgat gatgtcatgc gtgaacaacg tgagattatc tatgctcaac gttacgatgt
    71941 catcactgca gatcgtgact tggcacctga aattcagtct atgatcaaac gcacgattga
    72001 acgtgtcgtt gatggtcatg cgcgtgccaa acaagatgaa aaactagagg caattttgaa
    72061 ctttgctaag tacaacttgc ttcctgaaga ttctattacg atggaagact tgtcaggctt
    72121 gtctgataag gccatcaagg aagagctttt ccaacgttcc ttgaaggttt acgatagtca
    72181 ggtttcaaaa ctacgcgatg aagaagcagt taaagaattc caaaaagttt tgattctacg
    72241 agtggtggat aacaagtgga cagatcatat cgatgccctt gatcaattgc gtaacgcggt
    72301 tggacttcgt ggctatgctc agaacaaccc tgttgttgag tatcaggcag aaggtttccg
    72361 tatgtttaat gatatgattg gttcgattga gtttgatgtg acacgcttga tgatgaaagc
    72421 acaaattcat gaacaagaaa gaccacaggc agaacgtcat atcagtacaa cagcgactcg
    72481 caatatcgct gctcaccaag caagtatgcc agaagatttg gatttgagcc agattggacg
    72541 caatgaactt tgcccatgtg gttctggtaa gaaatttaaa aactgtcacg gtaaaagaca
    72601 ataaaatgag atagtttaga ggcggatatc ttgtgaaaag taaattttta ctgggtatcc
    72661 gtttgcttta taaggagatg agttatggta tttacagcaa aaagctctaa aataaatata
    72721 gaagaagttc gtgccttgtc aaaattagaa ggtcaggctt tggagaggaa atcacagcga
    72781 gatcaagagc tagaagccat tatacgtgga gaagaccagc gaattctctt ggtaatcggg
    72841 ccatgctcat ctgacaacga agaagctgtc cttgaatacg ctaagcgttt ggcagtccta
    72901 caagaagaag tggcagatcg tatctttatg gttatgcgtg tttatactgc caaaccccgt
    72961 accaacggag atggctataa gggcttgatt caccagccta acgcgacaga agcgcctagt
    73021 cttatcaatg gaatcaaagc cgttcgccat cttcactatc gtgtcatcac agaaacaggg
    73081 atgacaactg ctgatgaaat gctttatcct gaaaaccttc cgcttgtaga tgatttgatt
    73141 tcttacatgg cagttggtgc ccgttcagtt gaagaccagc aacaccgctt tgtggcaagt
    73201 ggggcaggat tttctactgg ttttaaaaat ccaacctctg gaaatctcaa tgtcatgttt
    73261 aatgggattt atgctgctca aaacaaacaa agtttccttt tcttaggaaa agaagtagaa
    73321 acaactggga acccgctttc acacgctatt cttcgtggtg ctcttaatga gtatggaaaa
    73381 aatattccca actactatta tgacaattta attgatacca ttgcccagta tgagaaaatg
    73441 ggcttggaaa atccttttat catcattgat accaatcatg acaattctgg taagcagtat
    73501 attgaacaga tccgaattgt ccgccagacc ttgattaacc gtgcttggaa tgaaaaaatt
    73561 aagcagttcg ttcgtggttt tatgattgag tcttatctgg aagatggtcg acaaaatgag
    73621 ccagaagtat ttggtaagtc tatcacagac ccttgcctgg gttgggataa cacagaagct
    73681 cttgtcagag aaatttacaa aacgttagga gaataagatg gcatttattg aaaaaggtca
    73741 agaaatcgat atggaagtca tcaaggctga aacccaattg tctgcggaag ccttgagact
    73801 caaggaaagc cgtgacaggg aattggcaga tattatttca ggggaagatg accgtattct
    73861 cttggtgatt ggtccttgct cttctgataa tgaagaggcg gtcttggaat atgctcgccg
    73921 tttatctgcc ttgcaaaaga aggtagcgga taagattttc atggtcatgc gcgtgtatac
    73981 tgctaagcct cgtaccaatg gagacggcta taaaggatta gttcaccagc cagatacttc
    74041 taaggctcca agcctgatta atggcttgca ggctgtgcgc cagttgcact accgcgtgat
    74101 tacagagact ggtttgacaa cggcagatga gatgctttat ccgtcaaatc tgatcttggt
    74161 ggatgacttg gtcagctacc atgccgttgg agctcgttct gtggaagacc aagagcaccg
    74221 ctttgtggct tctgggattg atgcaccagt agggatgaaa aatccaacct caggaaattt
    74281 gggtgttatg tttaacgcca tctatgctgc tcaaaacaag caaaccttcc tttatcatgg
    74341 gcaggaagtt gagacatcag gtaatccttt ggcccatgtt atcctccgtg gagcagtcaa
    74401 cgagtatggc aattatatgc cgaattacta ctatgaaaat ctactccaag ccattgaacg
    74461 ctatgaaacc atgggacttg aaaatccttt tatcctcatt gacaccaacc atgataactc
    74521 aggcaagcaa tatatggagc agattcgaat tgttcgccag accttgcaga atcgtgattg
    74581 gaatgagaaa attaaaaaga cggttcgagg atttatgatt gaatcttacc tagcagatgg
    74641 tcgtcaaaac caaccagaga tctttggttg ctctattact gacccttgcc taggttggga
    74701 aaatacagag gccttggtag aagagattta tgttaccttg acaaaataag tgaaaaggat
    74761 ggagttgggg aatctcaact ccttttgatg agaatgatag ttggacacgg aattgacatc
    74821 gaagaattgg cttcgataga aagcgcagtt acacgacatg aaggatttgc taagcgtgta
    74881 ctgaccgctc aggaaatgga gcgcttcacc agtctcaaag gacgcaggca aatagaatat
    74941 ttagctggtc gctggtcggc taaggaggcc ttttccaagg ctatgggaac gggcattagc
    75001 aagctcggtt ttcaggattt ggaagtcttg aacaatgaac gtggggcgcc ttattttagt
    75061 caggcaccat tttcaggaaa gatttggctg tctatcagcc acaccgatca gtttgtgaca
    75121 gccagtgtca ttttggagga aaatcatgaa agctagtcca catagaccaa ccaaggctct
    75181 gattcatctg ggagctattc gacaaaatat tcagcaaatg ggggctcata tccctcaagg
    75241 aacgctcaag ttggctgtgg tcaaggccaa tgcttatggt catggagctg ttgccgttgc
    75301 caaggcaatt caagatgatg ttgatggctt ttgcgtttcc aatatcgatg aagccattga
    75361 actcagacaa gctggactca gcaagccaat cctcatttta ggagtttctg aaatcgaagc
    75421 tgttgctcta gctaaagaat atgacttcac cttgacagtg gctggactgg agtggattca
    75481 agcactctta gataaggaag tggacctaac tggattgaca gtccacctca agattgattc
    75541 agggatggga cggattggtt ttagagaggc aagtgaggtt gagcaggctc aagatttgct
    75601 ccaacaacac ggtgtttgtg ttgaaggaat ctttacccac tttgctactg ctgatgagga
    75661 atcagatgac tattttaatg cccagttaga acggtttaaa actattttag ctagtatgaa
    75721 ggaagttcca gagctggttc atgctagcaa ttctgcaacg actctttggc atgtagagac
    75781 tattttcaat gcggttcgta tgggagatgc catgtatggc ctaaatccaa gtggagcggt
    75841 cttggatttg ccttatgatt tgataccggc cttgaccttg gagtctgctc tggttcatgt
    75901 caagacagtt ccagctggag cttgcatggg ctatggagca acttatcaag cggatagcga
    75961 gcaagtcatc gcgaccgtgc caatcgggta tgcagatgga tggacaagag acatgcaaaa
    76021 tttctctgtc ttggtagatg gccaagcttg cccaattgtc ggcagggttt cgatggacca
    76081 aatcactatt cgattgccta agccttaccc actcggaacc aaggtaacct tgattggctc
    76141 caatggggat aaggaaatca ctgcaactca ggtagcgacc taccgcgtaa ccattaacta
    76201 tgaggtggtt tgcctcctca gcgaccgtat tccgagagaa tattattaga aaagaaagga
    76261 gtggagcatg aatctacatc aacccttgca tgtcttgcct ggtgtgggac caaagtcagc
    76321 agaaaaatac gccaaactag gaattgaaaa cttgcaagat ctcttgctct actttccttt
    76381 ccgttatgaa gacttcaaaa ccaagcaggt gctggagctg gaagacggtg agaaggcagt
    76441 tctttctggt caggtagtga ctcctgctag tgtccagtat tatggtttca agcgcaatcg
    76501 cctgcgtttt agtctcaagc agggagaggt cgtttttgcg gtgaatttct ttaaccagcc
    76561 ctatctggct gataaaatag agttgggagc aacccttgct gtctttggaa aatgggaccg
    76621 cgctaaggct agtctgactg ggatgaaggt tctggctcag gtagaagatg acctccagcc
    76681 tgtctatcgt ctggctcagg gaatcagtca ggccagtctg gttaaggtca tcaagacggc
    76741 ttttgatcag ggactggacc tcttgataga agaaaatctg ccccagtctt tactagacaa
    76801 atacaaactc atgtcccgtt gtcaggcagt ccgagctatg cattttccaa aggatttggc
    76861 agaatacaag caggctcttc gccgtataaa gtttgaggaa ctcttttatt tccaaatgca
    76921 gctgcagatg ctcaagtctg aaaatagagt tcagggaagt ggtctggttc tgaattggtc
    76981 tcaggaaaaa gtgacagcag ttaaagtaag tcttcctttt gccctgaccc aagctcagga
    77041 aaagagtttg caggaaattt taactgatat gaagtccgac caccacatga atcgtctcct
    77101 acaaggggat gtggggagtg gaaaaacggt agtcgctggc ttggccatgt ttgcggcagt
    77161 gacagcaggt tatcaggctg ccctaatggt accaacagaa atcctcgcag agcaacactt
    77221 tgagagttta cagaaccttt ttcccaattt gaaactggct ctcttgatag gttccttgaa
    77281 agctgcagaa aagagagagg tcttggagac cattgccaag ggtgaggctg atttgattat
    77341 cggaactcac gctctgatac aagatggggt ggagtatgct cgtcttgctt tgattattat
    77401 cgatgagcag caccgttttg gtgtagggca aaggcgtatt ttacgggaaa aaggtgacaa
    77461 tccagatgtc ctcatgatga cggcgactcc cattccacgg acgcttgcca tcacagcctt
    77521 tggagatatg gatgtttcca ttatcgacca gatgccagca ggtcggaagc ctattgtgac
    77581 gcgctggatc aaacatgagc aactacctca ggtcttgact tggttagagg gggaaattca
    77641 aaaaggttcc caagcctatg tcatctctcc tttgattgaa gaatcagaag ctctagattt
    77701 gaaaaatgcc attgccttat cagaggagtt gacgactcat tttgcaggca aggcagaggt
    77761 ggctcttcta catggtagga tgaagagtga cgaaaaagac cagatcatgc aggatttcaa
    77821 ggagagaaag acggatattc tggtttcgac gacggttatt gaggttgggg tcaacgttcc
    77881 caatgcgact gtcatgatta tcatggatgc cgatcgcttc ggtctcagtc aacttcacca
    77941 gcttagaggt cgtgtcggtc ggggggacaa gcagtcctac gctgttctcg ttgctaatcc
    78001 caagacggat tctgggaaag accgcatgcg tatcatgaca gaaacgacca atggatttgt
    78061 ccttgcggag gaagatttga aaatgcgtgg ttctggtgag atttttggaa ccagacagtc
    78121 aggacttcca gagttccaag tggctgatat tatcgaagat tttccgattt tagaagaagc
    78181 aagaaaggtt gctagctaca ttagttctat agaagcttgg caagaagatc cagagtggcg
    78241 catgattgcc cttcatctgg aaaagaaaga acatctggat taagctttct ctaaggaaaa
    78301 cttaagctag tttttaggtt tggctcttat actaaagtca tcaaaaagaa acgaggactc
    78361 tcatatgaca gtaacgatta aagtaaatta ccaaaccact ttccaaaaga aggaagcaaa
    78421 aaactagtat aaacagaaga gaaagcgaaa tgctcttttt tcgtttctaa aactactttc
    78481 agcccatcat cctaaaagta aagaatctaa attcactttc tatttaccct tctttcttgc
    78541 attgattaca tagatatgct acagttgtgg taacgattac aaaataaaag gagcatgcta
    78601 tgaaaaatcc agctttgcta gaagaaatta agacctatag aggaagggat gaggttccgg
    78661 aagactttga tgctttctgg gatggggaag tgaaaaatgt ttccacactt ccatcctacc
    78721 acttggagga aagagatttc cacattcctc aagtcaagtg ctatgagtta acatttgaag
    78781 gaagcaagga aggaaaggtc tatgcacgca ttgttcttcc aaagagtgag gagaaggttc
    78841 cattaatctt ccattttcat ggttatatgg gacgtggctg ggactgggcc gacatgctgg
    78901 gcttcaccgt agctggttac ggtgttgttt ccatggatgt gcggggccag tcaggttact
    78961 cacaagacgg cttgcgttct cctttaggaa ataccgtgaa ggggcatatt atccgtggtg
    79021 ctatggaagg tcgggaccac ctcttttata aggatgttta tctggatatt taccagttgg
    79081 tcgaaattgt tgctagtctg tctcaggttg atgagaagcg tctttctagc tatggtgcct
    79141 cacaaggagg ggctctagct ctagttgcag cagcgctcaa tcctcgaatt cagaaaacag
    79201 ttgccattta tcccttcttg tcagacttca gacgggtgat tgagattggt aatactagcg
    79261 aggcttacga cgaacttttc cgttatttca agtttcacga ccccttccat gaaacagagg
    79321 aggaaatcat ggcgaccctt gcctatatcg atgtcaaaaa tcttgcccat cgtatccaag
    79381 gtgaggttaa gatgattacg ggcttggacg acgatgtttg ctatcccatt acccagtttg
    79441 cgatttataa tcgtctgacc tgcgataaaa cctatcgcat catgcctgag tatgctcacg
    79501 aagccatgaa tgtatttgtc aatgaccaag tctacaactg gctctgtgga agtgagattc
    79561 cttttaaata tctaaaataa ggagtcgact ctaagcacaa aatcttaaaa attacaaaca
    79621 cgcatagtat caggggatta aaaaaacttg atactatgcg ttttatcatg gaaatatagt
    79681 aaaatgaaac aagaatagga caaaacgatc aggacagtca aatcgatttc taacaatgtt
    79741 ttagaagcaa atgtgtacta ttctagtttc aatctattat atttatagaa ttttttgttg
    79801 ctagatttgt caaattgctt aaaataattt ttttcagaaa gcaaaagccg atacctatcg
    79861 agtagggtag ttcttgctat cgtcaggctt gtctgtaggt gttaatactt ttcaaaaatc
    79921 tctttaaacc acgtcagctt cgccttgccg tatatatgtt
//
LOCUS       DAVLHB010000005        79016 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLHB010000005 DAVLHB010000000
VERSION     DAVLHB010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79016
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.005"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(153..1775)
                     /gene="groL"
                     /locus_tag="VXE36_000337"
     CDS             complement(153..1775)
                     /gene="groL"
                     /locus_tag="VXE36_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0778702.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1791..2075)
                     /gene="groES"
                     /locus_tag="VXE36_000338"
     CDS             complement(1791..2075)
                     /gene="groES"
                     /locus_tag="VXE36_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0778703.1"
                     /translation="MLKPLGDRVLLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2345..2740)
                     /locus_tag="VXE36_000339"
     CDS             complement(2345..2740)
                     /locus_tag="VXE36_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0778704.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2818..3579)
                     /locus_tag="VXE36_000340"
     CDS             complement(2818..3579)
                     /locus_tag="VXE36_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0778705.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3621..4247)
                     /locus_tag="VXE36_000341"
     CDS             complement(3621..4247)
                     /locus_tag="VXE36_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0778706.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4263..4580)
                     /locus_tag="VXE36_000342"
     CDS             complement(4263..4580)
                     /locus_tag="VXE36_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0778707.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4577..4876)
                     /locus_tag="VXE36_000343"
     CDS             complement(4577..4876)
                     /locus_tag="VXE36_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0778708.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5161..5352)
                     /locus_tag="VXE36_000344"
     CDS             complement(5161..5352)
                     /locus_tag="VXE36_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0778709.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5513..6187)
                     /locus_tag="VXE36_000345"
     CDS             complement(5513..6187)
                     /locus_tag="VXE36_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778710.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6193..6639)
                     /locus_tag="VXE36_000346"
     CDS             complement(6193..6639)
                     /locus_tag="VXE36_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0778711.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6753..7256)
                     /locus_tag="VXE36_000347"
     CDS             complement(6753..7256)
                     /locus_tag="VXE36_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0778712.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLNFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7253..7615)
                     /locus_tag="VXE36_000348"
     CDS             complement(7253..7615)
                     /locus_tag="VXE36_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV0778713.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7681..9546)
                     /locus_tag="VXE36_000349"
                     /pseudo
     CDS             complement(7681..9546)
                     /locus_tag="VXE36_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9578..10027)
                     /locus_tag="VXE36_000350"
     CDS             complement(9578..10027)
                     /locus_tag="VXE36_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0778714.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(10151..10867)
                     /locus_tag="VXE36_000351"
     CDS             complement(10151..10867)
                     /locus_tag="VXE36_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0778715.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11748..13163)
                     /gene="ply"
                     /locus_tag="VXE36_000352"
     CDS             complement(11748..13163)
                     /gene="ply"
                     /locus_tag="VXE36_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0778716.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13174..13506)
                     /locus_tag="VXE36_000353"
     CDS             complement(13174..13506)
                     /locus_tag="VXE36_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778717.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13577..14185)
                     /locus_tag="VXE36_000354"
     CDS             complement(13577..14185)
                     /locus_tag="VXE36_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778718.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14198..14656)
                     /locus_tag="VXE36_000355"
     CDS             complement(14198..14656)
                     /locus_tag="VXE36_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0778719.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14781..15180
                     /locus_tag="VXE36_000356"
                     /pseudo
     CDS             14781..15180
                     /locus_tag="VXE36_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15945..16205)
                     /locus_tag="VXE36_000357"
     CDS             complement(15945..16205)
                     /locus_tag="VXE36_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778720.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(16264..16815)
                     /locus_tag="VXE36_000358"
     CDS             complement(16264..16815)
                     /locus_tag="VXE36_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778721.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(16805..17002)
                     /locus_tag="VXE36_000359"
     CDS             complement(16805..17002)
                     /locus_tag="VXE36_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778722.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDSISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(17006..17800)
                     /locus_tag="VXE36_000360"
     CDS             complement(17006..17800)
                     /locus_tag="VXE36_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778723.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLTKGQKVVNVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(18208..18633)
                     /locus_tag="VXE36_000361"
     CDS             complement(18208..18633)
                     /locus_tag="VXE36_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778724.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(18762..19145)
                     /locus_tag="VXE36_000362"
     CDS             complement(18762..19145)
                     /locus_tag="VXE36_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778725.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMASG"
     gene            complement(19167..19373)
                     /locus_tag="VXE36_000363"
     CDS             complement(19167..19373)
                     /locus_tag="VXE36_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778726.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(19360..19521)
                     /locus_tag="VXE36_000364"
     CDS             complement(19360..19521)
                     /locus_tag="VXE36_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0778727.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(19880..20836)
                     /gene="lytA"
                     /locus_tag="VXE36_000365"
     CDS             complement(19880..20836)
                     /gene="lytA"
                     /locus_tag="VXE36_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0778728.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21212..22582)
                     /locus_tag="VXE36_000366"
     CDS             complement(21212..22582)
                     /locus_tag="VXE36_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0778729.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(22889..24055)
                     /gene="recA"
                     /locus_tag="VXE36_000367"
     CDS             complement(22889..24055)
                     /gene="recA"
                     /locus_tag="VXE36_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0778730.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(24110..25366)
                     /locus_tag="VXE36_000368"
     CDS             complement(24110..25366)
                     /locus_tag="VXE36_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0778731.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(25451..26467)
                     /locus_tag="VXE36_000369"
     CDS             complement(25451..26467)
                     /locus_tag="VXE36_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0778732.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26475..26993)
                     /locus_tag="VXE36_000370"
     CDS             complement(26475..26993)
                     /locus_tag="VXE36_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778733.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(26983..27426)
                     /gene="tsaE"
                     /locus_tag="VXE36_000371"
     CDS             complement(26983..27426)
                     /gene="tsaE"
                     /locus_tag="VXE36_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0778734.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(27512..28132)
                     /locus_tag="VXE36_000372"
     CDS             complement(27512..28132)
                     /locus_tag="VXE36_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778735.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(28515..29378)
                     /locus_tag="VXE36_000373"
     CDS             complement(28515..29378)
                     /locus_tag="VXE36_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0778736.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            29724..31739
                     /locus_tag="VXE36_000374"
     CDS             29724..31739
                     /locus_tag="VXE36_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0778737.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            31741..32373
                     /locus_tag="VXE36_000375"
     CDS             31741..32373
                     /locus_tag="VXE36_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778738.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            32514..32792
                     /locus_tag="VXE36_000376"
     CDS             32514..32792
                     /locus_tag="VXE36_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEV0778739.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(33301..33714)
                     /gene="ndk"
                     /locus_tag="VXE36_000377"
     CDS             complement(33301..33714)
                     /gene="ndk"
                     /locus_tag="VXE36_000377"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0778740.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(33825..37502)
                     /gene="rpoC"
                     /locus_tag="VXE36_000378"
     CDS             complement(33825..37502)
                     /gene="rpoC"
                     /locus_tag="VXE36_000378"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0778741.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(37535..41146)
                     /gene="rpoB"
                     /locus_tag="VXE36_000379"
     CDS             complement(37535..41146)
                     /gene="rpoB"
                     /locus_tag="VXE36_000379"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0778742.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            41562..41632
                     /locus_tag="VXE36_000380"
     tRNA            41562..41632
                     /locus_tag="VXE36_000380"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41594..41596,aa:Cys,seq:gca)
     gene            complement(41830..43161)
                     /locus_tag="VXE36_000381"
     CDS             complement(41830..43161)
                     /locus_tag="VXE36_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0778743.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(43452..44276)
                     /gene="endA"
                     /locus_tag="VXE36_000382"
     CDS             complement(43452..44276)
                     /gene="endA"
                     /locus_tag="VXE36_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0778744.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(44315..44503)
                     /locus_tag="VXE36_000383"
     CDS             complement(44315..44503)
                     /locus_tag="VXE36_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0778745.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(44496..45779)
                     /gene="murA"
                     /locus_tag="VXE36_000384"
     CDS             complement(44496..45779)
                     /gene="murA"
                     /locus_tag="VXE36_000384"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0778746.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(45803..46033)
                     /locus_tag="VXE36_000385"
     CDS             complement(45803..46033)
                     /locus_tag="VXE36_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0778747.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(46091..47128)
                     /locus_tag="VXE36_000386"
     CDS             complement(46091..47128)
                     /locus_tag="VXE36_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0778748.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAENNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(47112..47600)
                     /gene="coaD"
                     /locus_tag="VXE36_000387"
     CDS             complement(47112..47600)
                     /gene="coaD"
                     /locus_tag="VXE36_000387"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0778749.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(47590..48129)
                     /gene="rsmD"
                     /locus_tag="VXE36_000388"
     CDS             complement(47590..48129)
                     /gene="rsmD"
                     /locus_tag="VXE36_000388"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0778750.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(48194..49186)
                     /locus_tag="VXE36_000389"
     CDS             complement(48194..49186)
                     /locus_tag="VXE36_000389"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0778751.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(49298..49981)
                     /locus_tag="VXE36_000390"
     CDS             complement(49298..49981)
                     /locus_tag="VXE36_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0778752.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(50037..50777)
                     /locus_tag="VXE36_000391"
     CDS             complement(50037..50777)
                     /locus_tag="VXE36_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0778753.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            50811..51089
                     /locus_tag="VXE36_000392"
     CDS             50811..51089
                     /locus_tag="VXE36_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0778754.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            51167..52093
                     /gene="yidC"
                     /locus_tag="VXE36_000393"
     CDS             51167..52093
                     /gene="yidC"
                     /locus_tag="VXE36_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0778755.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(52168..52962)
                     /gene="pflA"
                     /locus_tag="VXE36_000394"
     CDS             complement(52168..52962)
                     /gene="pflA"
                     /locus_tag="VXE36_000394"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0778756.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(53088..54338)
                     /locus_tag="VXE36_000395"
     CDS             complement(53088..54338)
                     /locus_tag="VXE36_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0778757.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(54405..55232)
                     /gene="purR"
                     /locus_tag="VXE36_000396"
     CDS             complement(54405..55232)
                     /gene="purR"
                     /locus_tag="VXE36_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0778758.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(55499..56440)
                     /locus_tag="VXE36_000397"
     CDS             complement(55499..56440)
                     /locus_tag="VXE36_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0778759.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(56430..57686)
                     /locus_tag="VXE36_000398"
     CDS             complement(56430..57686)
                     /locus_tag="VXE36_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0778760.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(57688..58350)
                     /locus_tag="VXE36_000399"
     CDS             complement(57688..58350)
                     /locus_tag="VXE36_000399"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0778761.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKGAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(58313..58969)
                     /locus_tag="VXE36_000400"
     CDS             complement(58313..58969)
                     /locus_tag="VXE36_000400"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0778762.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(58980..59858)
                     /gene="rsgA"
                     /locus_tag="VXE36_000401"
     CDS             complement(58980..59858)
                     /gene="rsgA"
                     /locus_tag="VXE36_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0778763.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(59860..60732)
                     /gene="rsmA"
                     /locus_tag="VXE36_000402"
     CDS             complement(59860..60732)
                     /gene="rsmA"
                     /locus_tag="VXE36_000402"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0778764.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALNQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(60983..61276)
                     /locus_tag="VXE36_000403"
     CDS             complement(60983..61276)
                     /locus_tag="VXE36_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778765.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(61269..61910)
                     /locus_tag="VXE36_000404"
     CDS             complement(61269..61910)
                     /locus_tag="VXE36_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778766.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEAMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(61912..63942)
                     /locus_tag="VXE36_000405"
     CDS             complement(61912..63942)
                     /locus_tag="VXE36_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0778767.1"
                     /translation="MKRLFILISMVLVSLYMEITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GARPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRDLMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(64019..64315)
                     /locus_tag="VXE36_000406"
     CDS             complement(64019..64315)
                     /locus_tag="VXE36_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0778768.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(64636..65535)
                     /locus_tag="VXE36_000407"
     CDS             complement(64636..65535)
                     /locus_tag="VXE36_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0778769.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(65607..66167)
                     /gene="rnmV"
                     /locus_tag="VXE36_000408"
     CDS             complement(65607..66167)
                     /gene="rnmV"
                     /locus_tag="VXE36_000408"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0778770.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSCKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLVEVEEAMKSYE"
     gene            complement(66167..66940)
                     /locus_tag="VXE36_000409"
     CDS             complement(66167..66940)
                     /locus_tag="VXE36_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0778771.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYIRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(67245..68138)
                     /locus_tag="VXE36_000410"
     CDS             complement(67245..68138)
                     /locus_tag="VXE36_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0778772.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSTPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLAAATSGFALLGRKTRRRK"
     gene            complement(68422..68556)
                     /gene="rpmH"
                     /locus_tag="VXE36_000411"
     CDS             complement(68422..68556)
                     /gene="rpmH"
                     /locus_tag="VXE36_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0778773.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(68701..69915)
                     /locus_tag="VXE36_000412"
     CDS             complement(68701..69915)
                     /locus_tag="VXE36_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0778774.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(70071..70364)
                     /locus_tag="VXE36_000413"
     CDS             complement(70071..70364)
                     /locus_tag="VXE36_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778775.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            70526..70978
                     /locus_tag="VXE36_000414"
     CDS             70526..70978
                     /locus_tag="VXE36_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0778776.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(71013..72401)
                     /locus_tag="VXE36_000415"
     CDS             complement(71013..72401)
                     /locus_tag="VXE36_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0778777.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDMLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            72467..73429
                     /locus_tag="VXE36_000416"
     CDS             72467..73429
                     /locus_tag="VXE36_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0778778.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVHFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(73635..74645)
                     /gene="ccpA"
                     /locus_tag="VXE36_000417"
     CDS             complement(73635..74645)
                     /gene="ccpA"
                     /locus_tag="VXE36_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0778779.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(75070..75669)
                     /locus_tag="VXE36_000418"
     CDS             complement(75070..75669)
                     /locus_tag="VXE36_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0778780.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEMVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(75671..76768)
                     /locus_tag="VXE36_000419"
     CDS             complement(75671..76768)
                     /locus_tag="VXE36_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0778781.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILTVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(76768..77505)
                     /locus_tag="VXE36_000420"
     CDS             complement(76768..77505)
                     /locus_tag="VXE36_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778782.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(77507..78391)
                     /locus_tag="VXE36_000421"
     CDS             complement(77507..78391)
                     /locus_tag="VXE36_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778783.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENIIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(78378..78572)
                     /locus_tag="VXE36_000422"
     CDS             complement(78378..78572)
                     /locus_tag="VXE36_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778784.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFICGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(78569..78775)
                     /locus_tag="VXE36_000423"
     CDS             complement(78569..78775)
                     /locus_tag="VXE36_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778785.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        23135 a        17877 c        14467 g        23537 t
ORIGIN      
        1 atcgctctga acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagctgact
       61 tcaacccact acagttgaca aagagcctat aaaaagaagg gttagtcatt ccctcctttt
      121 gtgtttttta taagttgttt tctatagaaa gcttacatca tcccgcccat catacttgga
      181 tccattgctg gagctggggc tactggttct ggtttattgg ctacgactgc ttctgttgtc
      241 aaaatcaagc tggctacaga tgctgcattt tgtagggctg aacgactcac tttaactgga
      301 tcaatgatac cttgatcaat catgttaacc cactcgccag ttgctgcgtt gaatcctata
      361 ccaagctcag catttttcaa acgatcgata acgatagatc cttcaaatcc tgcattgtga
      421 gcaatttgac gaacgggttc ttccaaagca cggagaacaa tattacgtcc tgttgcttca
      481 tctcctgtca attccaaggt agcaacagct ggaatcacat tggcaagagc tgttccacca
      541 cctgcaacaa taccttcttc aacagctgca cgagtagcgt tgagggcatc ttcaatgcgg
      601 agtttcattt ctttcaactc agtttcagtt gcggctccga ccttaataac cgctacacca
      661 cctgacaatt tggccaagcg ttcttgcaat ttttcacggt caaattcaga agttgtagtt
      721 tcgatttgag acttgataac cgcaacacgg tgagaaatcg cttcaggatt tcctgcacct
      781 tctacaataa ccgtgctatc tttgtccacg gtcactctcg ctgcttgacc aagagcttca
      841 attgtcgcat ctttcaactc aagaccaagg tcttctgtga taactgttcc gcctgttaag
      901 atggcgatat cttcaagcat ggctttgcga cggtcaccaa aaccaggtgc cttgactgct
      961 actacgttga aggttccacg aatcttgttc aaaacaagag ttggaagagc ctcgccatcc
     1021 acatcatccg caataatcaa gagtggacga ttgctttgga gaatgctttc caaaagtggc
     1081 aagatttctt ggatattgga aattttcttg tctgtaatca aaatgtacgg attttcaagg
     1141 tcagccacca ttttttcgct atcagtcacc atgtactgtg aaaggtaacc acggtcaaac
     1201 tgcattcctt ctacgacttc aagctctgtt tccataccac gtgactcttc gatggtgatg
     1261 acaccgtctt tgccaacttt ttccattgct tcagagatgt actcaccaac tttttcagaa
     1321 cgagaagata cggctgcaac ttgagcgata gcttctttat tggcaacagg gatggcgttg
     1381 tttttcaaag cttcaactgc tgcggcaact gctgtttcaa tcccacgacg aataccgatt
     1441 ggatttgcac ctgctgtgac gtttttgatt ccttcacgga cgatagcttg ggtcaagact
     1501 gttgcagtcg tagtcccgtc acctgcgata tcattggttt tagaagctac ttctgatact
     1561 aacttagcac ccatattttc aaaatggtct tccaattcga tttctttggc aatggtcaca
     1621 ccgtcattgg taatcaaggg tgaaccgaat gacttttcaa gaacgacatt gcgacctttt
     1681 ggtcccaagg ttactttaac agtgtctgca aggatatcga caccacgaac catggctgaa
     1741 cgggcatctg atgaaaattt aatttctttt gacatactta ctttctcctt ctattcctca
     1801 atgattgcca aaatgttagc ttcgcctacg atgatgtact tttcatcgcc atctttgaca
     1861 tcaagacctg cgtgggcttc aactaagaca cgatctccag ttttaacact tggagcaacc
     1921 aagtcaccgt tcaaggtacg aacaccttgt ccagtagcca caacttgagc tgttttggtt
     1981 ttttcttggg ctgagcctgc aaggacaaag cccccaacgg tttgttcttt ttcttctatt
     2041 tttaagagca cacggtcccc taatggtttc aacatctgat ttcctccata atgagataga
     2101 tattattagc actctttgaa ctggagtgct aattcataat tctattgtat cacttggtca
     2161 gaaatagtca agaaaaaagt ctgactttct caagataaaa agcctgagac caactcagac
     2221 tttttaatgt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg
     2281 ctcaaagcat tgctttgatg ttgtggataa agctaacgtg gtttgaagag attttcgaag
     2341 agtattaaaa tggcaattct tcctcttcca agactaaatc tgccaaatct tggcctgcat
     2401 tattttcacg catagcacgt tgggcacgac tttccaagag ttggaatcct gttacaagta
     2461 cttcggtcac gtagttcatt tggccatttt tctcaaagcg acgggtacgc aattctccat
     2521 caacggaaat gagactacct ttggttgcgt agcttgccaa agtttctgct agtctgcccc
     2581 ataggaccat attgacaaaa tcaacttcac gttcaccgtt ttggtctttg taacgacggt
     2641 tgacagcgat agttgctcgc gctactgact tgtcattgtt ggttttgtgc aattctggtg
     2701 tagacgttaa acgtccaatc aagataactt tattatacat attttcttcc tcctacttat
     2761 ctattcgtag gaaatcaaaa aaagttacag aaatttgtaa cttttcgaga aaatttttta
     2821 ttttttatga accatgaaac ctgtcgcctg ttgattggcc ataatggtca tatctgtaat
     2881 ctgaacacga cgaggttgac tagtcacata gactactgta tctgcaatat cctgagcttg
     2941 caaagcttct attccttggt aaacggacgc agctcgttct ttatcaccat gaaaacgcac
     3001 tgtagaaaaa tctgtttcga caattccagg ctgaatggtt gtcaccttga tatccgttgc
     3061 gatggtatca attcgcagtc catccgaaaa ggtcttaacc gcagccttgg tagctgagta
     3121 aacagcggca ccagcatagg cgtagattcc tgcggttgac cccatattga taatatgacc
     3181 ttgattgact tttatcattg ctggcaagaa acagcgagta accgccatca gacctttaac
     3241 attggtatcc aacatggtca acatatccaa ctcctcatag tcttgatagg gagccaagtc
     3301 aagagccagt ccggcgttgt tgaccaagat atcaatcctc cctatcgttt ctagaatatc
     3361 agagcaaaca gtcttcacca tgaccatatc cgtcacatct agtggaaaag tccagacggt
     3421 ttgatttgga aagcttactg caaactccga cttgaggatt tctaatctgt ctatccgtcg
     3481 tcctgttaga acgacatcct caccctgctc cagataagca cgcgcaatcg cttcaccgat
     3541 tcctgaggtt gctcccgtaa tcacaacatt ttttgccatc ttatttcctt ctagctggtc
     3601 tatcagatat taacaacttc ttaggcagtc cagtgtttag ctgagtcaaa tggtgttccg
     3661 acaacttggt cttctgataa ttcaagcaca ccacgttttt gtggagcatt tggcagatgc
     3721 aattcacgag gactgcacat cataccaaaa ctcttttcac cacgaagttc acctgggaaa
     3781 atgagattcc cttttggcat catagctcca ggaagcgcga caatggtttt caaccccaca
     3841 cgcgcattgg gagctcctgc aacgatttgt acagtcttat cacttgcgac tgcaacttgg
     3901 cagatgttga ggtggtcact atctggatgg gctaccatct caacaatttc accgacaaca
     3961 aacttaggtt ccttatcatt aacaatttct tctgtaaaac cttccgcctg caactcttgg
     4021 ttcaaacgag cgacttgctc atctgtcaaa aagacttgac cgcgctctgc agtttcaaat
     4081 aaacttgaaa cttcgaaaat attccaagcc actgtttccc cattttcttt gaggaaaaca
     4141 cgggctacct tgcctttgcg ttccacattc agtttggcat ctccgctatt tttcacgatg
     4201 accataagga catcaccgac atgttctttg ttatacgtaa aaatcattgt ttcctttttc
     4261 tcctatttca atcctgctaa aaaatcgtta atttgctcct tacttttacg gtcgcgattg
     4321 acaaaacgac cgatttcctt gtccttttct agaacaacaa ggctaggaat tccgtaaaca
     4381 tcccagagtt tggccaaatc catatactga tctcggtcca ttcgaataaa ggtgaactct
     4441 ggattggtct cttcaatctc tggtaaggca ggataaatat aacgacaatc gccacaccag
     4501 tctgccacaa aaaggaagac cttcttgccc gctttttcca ctaaagatgc taattcttct
     4561 aaacttgctg gctgtatcat aagacttcct cctcatagac taggtcttca ttttcataga
     4621 caaaggtata atgacggcca tcctcaaaaa tgacgccacc aaccaagctc tccagactgc
     4681 tttcgtaaac ttgaacataa agggtcgcaa tttcccccat gtcggaaaaa tggtctcgca
     4741 caatctctgt caactcttcc tgagtcttca tgagcttacg gtcatctgca acttttttcg
     4801 tagcaagagc aaggcttccg atacctagca gagccaagcc tgccatccac atttttttag
     4861 ctttcatacc attcatttta acacaaaaaa ggcttcagga caaatgagga agcagcagaa
     4921 aagcaagtaa aaagcctctt cctttaagga aaaggacttc ttatactaag agcaaactag
     4981 aaagctagcc gcaggctgct caaaacacgg ttttgaggtt gtagataagg cgacgttgac
     5041 gtggtttgaa gagattttca aagagtatta ttcttattgc caggcaccta agttgccaac
     5101 gtagtaacca tcaggtgtgt aggtattgcg aagcatctta cctgatgaag ccagataata
     5161 ctacttgcca ttgtctttga cccaatcatt cgcaatcatg gaaccagaag aacttacata
     5221 ataccattct cccttgtcat aaacccaagt actgactttc atggttcctg agcaattaaa
     5281 ggcaaaaaaa ctgtccaata tcattcgttt tttaaaagca ttcgacacta catcatctac
     5341 gctgtagtac atagatacat caaacgtaaa agccaaaata tcgaaaaata tacaactttt
     5401 aaaggcagca tttcattttt taaagtctaa caaccataga actgaaatca gagcaaggca
     5461 tcaatttcct actctatagt acgcctattt tgatggttga agtgaagatt ttttatttaa
     5521 cgtagacaat ttccaacttc ccaaaagcca catctccacg gataatcaag gttttgctgg
     5581 ttggggctac aggagcgtca gccttagctg caccaaagga ggtttctact ttcaaatcta
     5641 cacgccagtg ttgtggaaca tagacggttg catttccgaa ggctacttca atatttaaag
     5701 ttgcaaaatc acctagcatc tctgcattat catagtagat tttagcatcc ccaaaagcga
     5761 cttccacttg gtcatctacg agatcttgat cttgcttata gaaggtcccg ctaccaaaag
     5821 cgacttcctt atccgtgacg actgtttttt tcccattgta ccaccatttt ttttcattcc
     5881 agaacttact tgaatgcgtc agataaccaa caccaagtac caccaagatg ctagcccaaa
     5941 taagagaatg attggtaact ggtaacaagt cataagcgta atttgcaatg atgagcgcca
     6001 gtaaacctgt aaaaactgcc gaagtgagat gacgtctaag gatggactca atggacttat
     6061 aagcaaaaaa aacaatacct agtaaaggcc atattttacc atccaaagaa ggaattccaa
     6121 aattcccttg cagcaagatc caagctgcta aaaccaataa aacaatacca aatgctttct
     6181 ttttcatgtt ttttacctca tgtttcttag attttctttt aggagggatt ggtaatgccg
     6241 tgagacatga acctccttgt gcgtctgata aaaggaaatg gtgcccgttc ctgaaaagga
     6301 cttgtccact gagtaaatct gacggatgtt tgcgatcgtt gacttggaaa ctcgattaaa
     6361 atagcgaggc aagatagact ccaactcata gagcttgagg cgaacctcat aagcttcctt
     6421 ctggttatga gcgtagatct tgctcccttc tgtttcaaag aagagaattt ctgacaggtc
     6481 tagataatat tcacctgtcc ccttgtaaaa agtcaacctc ggagcctttg actcttgcaa
     6541 gagccgttgc aagtctgcaa tttcatctgt caaagtgggg gtcttgatga caatttcagt
     6601 ctcctctaaa ttgccgtcaa tctcaattcg taacttcatc acatctcctt tctgactcta
     6661 ctatatcaaa gctaagttag gaatacaagg gcaaaaaagc aagtggtcaa tttgaagcag
     6721 taagtggttg taggactagc ttaacttaca tgtcagaata ggaagaaaag gaatccccac
     6781 accaaaccac aagcatagcc aaccaagaca tccttgggat aatgaacacc ccctaaaacc
     6841 ctcaccaacc ccagcaaagc tgaaaagttc aagcatacta agccaatagg tagactagca
     6901 tgcagacagg ccatggagat gatagttgcc gaaaagacat ggcgactggg catcgaccgt
     6961 cccgaactat ccttatcaag aaggggacag atatcccaag tttcataagg tctcgggtga
     7021 ttgattttct tacgaaacag ggacaaggtc acaaaacctg atgcaggaat aagcacataa
     7081 accccaactt gctgaccaag tcctagttgc aggtaagtgg tgactagcaa gatcagatag
     7141 accaggggca tggcgactgt catcaaacga ttgaaactgc gtaataggaa taaaagaatt
     7201 ggacgactag ttagtctgga gctgatattt cgataccatt cttgataatt tttcatttat
     7261 gcttctcata cttttctaga acttgttgag atgttttccc cttggcaagc caatccacta
     7321 gcttgtccaa gcgacgtatt tcctgcatca gaggatcatc aatttcctca atacggacac
     7381 cgcaaatctt ccctgtaatt gcaattcgtt cagggacata atatggtgct tgtctaaaaa
     7441 aatctccgta agtaacatcc ctatccagac aagcaagaac atcactcact tcataccctg
     7501 tcaaccaact ggtcacttgg tgaactgact ctgcctttcc accctttcgc tcaacttttg
     7561 caatcaaggc taagtagaca gcagcaaatt tcatattgta taatttctga ctcatacttc
     7621 tctctttcta tgtgtactag tataaataag aaaaagaagg ccgtcaagcc ttcttttgat
     7681 ttattcttct gcttcatctt ctgtaaattg actattgtac aagtcagcgt agaagccacc
     7741 ttgcgccatc agttcctcat agttgccttg ctcgatgata tttccatctt tcatgaccaa
     7801 gatcaagtct gcatttcgga tggttgacaa gcggtgggca atgacaaagg atgtgcgtca
     7861 ttccatcaaa cggtccatgg ctttttggat caattcctct gtccgtgtgt caacagaaga
     7921 agtcgcctca tccaaaatca aaagcggtgc atccttaaga agggcacgag caatagtcaa
     7981 tagttgtttt tgtcctacag acaaggtcac ggtgtcatcc aagatggtat catagccatc
     8041 tggcaaggtc ataataaagt ggtgaattcc cacagcctta ctagcttcca tcattcgttc
     8101 atcactaatc cctatttgat tatagatgag attgtctcga atagttcctt caaagagcca
     8161 ggtatcctgc aagaccattg aaaaggcatc atgcacttct gaacgcgtca tagccttggt
     8221 atccacacca tcaatgcgaa tacttccctt atcaatctca tagaatttca tcaaaagatt
     8281 gacaatggtt gtcttaccag ccccagtcgg cccaacaatg gcaacctttt gaccagcatg
     8341 agctgtcgca gagaagtcat agtcttgaac attgacaccg tccaccagaa tttctcctgc
     8401 tgacacgtcg tagaaacgtg gaatcagatt gaccagagtt gatttaccag aacctgttga
     8461 cccaataaag gccactgttt gaccagtttc tgctttaaag ctaacatgtt caataactgc
     8521 ctccgaattt gccgcatagc ggaaggtcac atccttaaac tcgacctgac ctttgaagtt
     8581 ttcatcagtc agctgcactt gaacagggtt ttggatagaa gaatgcaaat ctaaaacttg
     8641 attaatccgc ttagcagaga ccatagttcg gggaagaacg atgaagagtg ctcccatgag
     8701 aaggaagccc atgacaacct acatggcata agacatgaaa acaatcatgt cactaaagag
     8761 aggcagacgc gctatcggag cagcgtcgtt aatcacatag gccccaatcc agtaaatcgc
     8821 tacactcaaa ccacttgaaa tccccatcat gataggattc aaaatagcca taagacggtt
     8881 gacaaacaaa ttcaaacggg tcaattcatc atttactgct gcaaattttt cattttgata
     8941 atcctctgca ttgtaggcac gaacgacacg aatacctgtt aaactctcac gagtgatact
     9001 gttcagttta tctatcagcc cctgaatcaa ggactgtttt ggaaagtcta gcgtcatcaa
     9061 aacggtcgtc atcaggacgt tgacaatcac tgccacaagt acggcccaaa gccagtattc
     9121 tgaatgacct aaaatcttcc caatagccca aatagccata attgaaccac gcgttaccac
     9181 ttgcaagccc atagtaatca acatttgaac ttgagtaatg tcattggtag tacgcgtcaa
     9241 gaggctagga attgaaaatt tcttaatctc tgtctgcgag taatccaaaa ctcggttaaa
     9301 aatatcactt ctcagcctac tagtataaga agccgccact cgggatgcaa aaaatccaac
     9361 tgcaactacg gacaagaagg caagaaagag cattcccatc atcatgcttg ccggctgcca
     9421 caactcatct aaattagttc cttgactacc tagcaaatcc gtaattttcg agatataggt
     9481 cggcacttcc aactctagat agaccgaaaa gcaagtaaag agaatggcta gtaaaatcat
     9541 ccccattctt ttctactaat tcttttggct aatttcttta ttctctcctc ctattccctt
     9601 gatattttgc ctgtagttga ccgagaacct tctcaaaaat cagtaattca tcttcatcaa
     9661 tgtcttccat caactgcttg tctatgcgtt caaaaaaagc cttaacctgt tgcatctgag
     9721 aacgtgcttt gtccgtcaga cgaacaaact tagcccgctt atcaacagga ctcgcctcca
     9781 attccaccaa accattttgc actatacgct taaccagatt actagcaaca gacttggtaa
     9841 tattgagttc ctgatcgata tctttaatca agaccaagtc ttggtttttc tcgcgattat
     9901 ccaaaaaatg cacaacctga ccttgcggcc cacccataaa ttcaatgccg caacgtttgg
     9961 cttccttttg caccatcagg tgaatttgat gaccaaaacg cttaaagact aacatcggtt
    10021 tacccataat ctcccccttc taaataaaaa tagttctctg gagaataatt aaatttctat
    10081 gagaactatt ttcttgatta aaaaaatccc aagtgatttt ctcacttagg atcatgttct
    10141 ataggttaaa ttaaaaccca tctacgttcg tataaatctt ttggacgtct tcgtcgtctt
    10201 caagaacgct gtaaagtttt tcaaaggttt caaggtcttc gcctgacaat tccacttctg
    10261 actgaggaat catttccaat tcagtcactt ggaattcttc aataccagac tcacggagag
    10321 caacgatagc cttgtgaagg tcagttggcg ctgtgtaaac tgtgattgta ccttcttgtg
    10381 cttctacgtc atccacatcc acatccgctt cgagcaattg ctcaaagact gcgtctgcat
    10441 cttcacctcc aaatacaata acacctttgt tgtcaaagag gtaagaaaca gaacctgaag
    10501 cgcccatgtt tccgccgttt ttaccaaagg ctgcacggac attggctgct gtacggttga
    10561 cgttagaagt caaagtatcc acaattagca tagagccatt tggcccaaaa ccttcgtaac
    10621 gtccttctgt aaaggtttcg tctgtgtttc ctttggcttt atcaatcgct ttatcgataa
    10681 tgtgttttgg cacttgggct tgtttagcac ggtcgataac gaatttcaaa gctgagtttg
    10741 attctggatc tggatcacct tttttagctg ctacatagat ttctacacca aattttgcat
    10801 atactttaga gttggctcca tctttagccg ttttcttggc tacgatattg gcccatttac
    10861 gtcccattag gaatctcctt ttttcacatt ttaatctttc ttattataac acaagttttt
    10921 ttgattttca ctagaggaaa tggattttat tagcaaatca agctaggata gcactttacc
    10981 tgctaagatg gtcttgcctt tctatcttta tcaacagaca ctcatccaca ttcaaaaaac
    11041 aaactagacc attatctgca aatagaaagt ttcagccaag tttgacaaag tcagctcaaa
    11101 ttactgtttg aagtttgtag atataagcga caaaaacaat catactgcac cttttgttga
    11161 cagtctactc cagacatatc atagttcaag taaatacttt gaaattcaac agttcttata
    11221 ggcgctattg tattctaaga aatcaataga agagtttcta agcaaacctc taatactcaa
    11281 taaaaatcaa agagcaaact agaaagctag cctcaggttg ctcaaaacac tgttttgagg
    11341 ttgcggatgg ggctgacatg gtttgaagaa attttcgaag agtataattt acgtgttccc
    11401 aagatggaga agttagacta gtacactggc acttctaaaa cattgctagc aattgatttg
    11461 ttcatattta atttcatttt ttccataaat gggtattaga tataaacagc aaaatatttc
    11521 cgatacgtgt cgttcttgaa tttccaatca tctaaaacaa gtaaaggata atcaatcccc
    11581 tgtatatcaa ggaattggct acccttttta cttttttaca cattctgttt gatagattca
    11641 ttttaacatc acgagcatac tccaatggaa atcgctaggc aagagataaa ctttcagata
    11701 tccgcagaga gatcatcgcc tctttttgtc gcaagcattc tcctctccta gtcattttct
    11761 accttatctt ctacctgagg atagagagtt gttccccaaa tagaaatcgt ccgcttacgc
    11821 actagtggca aatcggtttt ttcataaacc gtacgccacc attcccaggc aagcccggta
    11881 cactctctaa ttttgacaga gagattacga acattccctt ttaaaggaat actagtggta
    11941 aagtgagccg ttaaatcctg cccatttctg tcccaagcct taggagtcaa gacttcctta
    12001 ccttgatgat cataggataa ttcattccaa gtaatataat attgggcaac ataggcacca
    12061 ctatgatcca gcagtaaatc tccgtttctg taagctgtaa ccttagtctc aacatagtct
    12121 gtactatttt gaaaggtcgc aactacattg tcacgtaaaa aagaagttgt ataggaaatc
    12181 ggcaagcctg gatgatctgc tgtaaagcga ctgccttctt gaatcaagtc ctctaccata
    12241 tccaccttgc ctgttacaac tcgggcaccc gaacttgggt cgccccctaa aataaccgcc
    12301 ttcacttctg tattgtccaa aatctgcttc cactctgtct gaggagctac cttgactcct
    12361 tttatcaaag cttcaaaagc agcctctact tcatcactct tactcgtggt ttccaacttg
    12421 agatagactt ggcgcccata agcaacactc gaaatataga ccaaaggacg ctctgcagaa
    12481 attcctctct gttttaaatc ctctaccgtt acagtatctt gaaacacatc tcctggattt
    12541 ttaacagcgt ctacgctgac tgtataataa atctgcttaa aattaacaat ctgaatctgc
    12601 ttttcgcctg aatggacaga gttaaaatca atatcaagag aattccctgt cttttcaaag
    12661 tcagaaccaa acttgacctt gagttgttcc atgctgtgag ccgtgatttt ttcatactgc
    12721 attctagctg ggacattatt gacctgacca taatcttgat gccacttagc caacaaatcg
    12781 tttaccgctc cgcgaacact tgaattgctg gggtcttcca cttggagaaa gctatcgcta
    12841 cttgccaaac caggcaaatc aatactataa gtcatcggag cacgatcgac cgcaagaaga
    12901 gtgggattat tctctaacaa ggtctcatcc actacgagaa gtgctccagg atagaggcga
    12961 ctgtcgttgg tagctgttac agaaatatca cttgtatttg tcgacaagct ccgcttcttt
    13021 ctttcgataa caacaaactc atcgggtagc tgattaccct ctttgatgaa acgattttca
    13081 atactttctc cctgatgggt caagagtttc tttttatcgt aattcatagc tagtataaag
    13141 tcatttactg ctttatttgc catcttctac ctcctaataa gttcctggat tgagttgcat
    13201 aaactcagac ttgttcagcg aaatcagccg tggttggact aagtaatcca aaatttcctc
    13261 gtacaattct tctgagacat tgcgtcgccg tctggctaaa taagaagtcg gaatgaccgt
    13321 attatccaac ataaatacct tatctaagtc aatcaaggtt ggtcttgtaa aaggattacg
    13381 agctagatcc ggctcttcta tcataaagtt cttgaccaaa cgtctggtca agagagctgg
    13441 tttgaaggtc tgatttttaa ccaactcttt gtttttagtc atgctgttgt caatacagat
    13501 atacatatga ttcttcacag ccaaatcgct actaatagtc ggaaaaggca aataaagagc
    13561 tacaacatct cctctcttaa tcaagcaaga gcaccccctt ttctcctaat gtaacataga
    13621 caggattgac caagtcttct gattgactca gaatttccaa agtttgagtt tggcgcgctg
    13681 tcaatttagt agcatcttgt ctcttcaata caaaatgctt gtcgccaata accttgacaa
    13741 tataatcctt ctccaaagct gactggtaaa tccacatcag atgttgtctg tcctgagaac
    13801 tcaagagaga aggattttca agcctcccga tagtctgata aaaatcaaaa acaggagcta
    13861 actcctgcca atctgattgg ctagttgtca aggctagaaa aagggctttg cgagctgata
    13921 cttcttggtt agccttgaga gttactttcc cctccaagtt ttttagaaat cgggaaactc
    13981 cagaaagcaa atttttctct aactgcgaga aataaaaacc tttcgttccc agacataagt
    14041 ctttcatgtc gctttctcta gcaaataaga gctcaaacat ttgatagtaa aagaaaaata
    14101 tctggcactg ggtcgcgctc atcttttcct tatcggcttc tttttttaac cagagcaagg
    14161 gcgacaggta gctggattga gacatttcct ctacctccta ctctttttta actggagcat
    14221 ctgcactagc tgccacttct tttgactgga tactttccca ctggttaatc tcctctgaga
    14281 taagaccttc gcatgtcttg acaaataggg caaaagcctt ggtctttcct gcatatttct
    14341 ccgtttggca ttgatagagg aatttttctt tctccaggag ttgcgcagtt ttttggtaag
    14401 aaatccaatt ttcctttgca ttatacaaat tgataatccc ctcacacagc aagccgagac
    14461 tggataaggc aaccgaaatc aaacggtagc gatcacctgg cataggaata gcacaaaaga
    14521 cagctatgag gaaacctgcc acgatttctg ttatttttaa taccttatag cgcctacgat
    14581 gttgaacgct tttctttaaa aaatgagcta tctgtacgtc taatcgctct gtcaggtaca
    14641 tttcttctgg cgtcatattc gtaactcctt tcatttactt tgataaccat agtataacat
    14701 atttgaatat caaagtatag taaaaactgg actataactt attagactcc ctgcgaaaca
    14761 aaatatggta tagtagttct atgaattatg aagcaagtaa acaattaact gatacacgat
    14821 ttaagcgtct tgttggtgtt cagcgtacca cttttgaaga gatgttagct gtattaaaaa
    14881 cagcttatca aaaaagtcgg acaagctggt aaaatcttgg ctgacagtaa ttatcaaggg
    14941 ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact caagccacta
    15001 acagttgaag ataaagtcta taaccatgcg ctatctaagg agagaagcaa ggttgagaac
    15061 atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctgtcgaaa tcatcgtaaa
    15121 cgcttcggat tacgaatgaa tttgagtgct ggtattatca atcatgaact aggattctag
    15181 ttttgcagga agtctattat atatatgcac agacatatga aatctttttg atacagcctt
    15241 ctttttacat agagagacag cagttatgat atatttatcc attcacaaca tcttctgtac
    15301 caatactaca ataattggta cattttgatt acacaatcgt ttcaaaaaat atgatggaag
    15361 actgagtatt ttatagtaat tcccttccta tcaactagat caaccagttg agtgttgaat
    15421 gttgaaacac cctagcctca gcaaaggact atgatcagca tttcctagcc aataggacgc
    15481 tccaaatcac ctattctaag tccatcacta gcttggtcag taagatacag actgcaaggc
    15541 aagactgacg tggttgatga gattttggaa gagtattaca atcatagatt caccagtaga
    15601 cttgaccgca gatttaacta tagtagattg aaactagaat agtacacttc tgcttctaaa
    15661 acattgttag aaatcgattt gactgtcctg atcaatttgt cctgttctcg tttcatttta
    15721 ctatactaaa aaaccacctg aaacaaatca agtgactaga ggataaaaac aaagactggg
    15781 caaaaagttt tgaaaagcaa aaaacgcata atatcaggtc ttgaaaaacc ttgatactat
    15841 acgtttgatt gtgggaagat tgacttcatt ttctcctgaa attgaagttt tttctagttt
    15901 ccaggtatag acgaattcaa tatagccatc tcgctacaat tattttaacc atcgaaaaaa
    15961 tttttcagaa tttcaaaaat ttcattttga tccaatgaaa tgtcattatt ttgaagaata
    16021 gttgacttca caggctctaa ttctatcaca aagcggtgca tgtctgcttt taccgcacta
    16081 cttgatgtta tagccgataa cttttcatct cctagcaagg aagctgtcaa acgggtaagg
    16141 tcattcaaat gctttttaat ggacttactt aaaccttgag cacctgtggc agagcgctcc
    16201 ctcatatcca gccaagcttt agccttaaaa ataattaata ctcaatgaaa atcaaagagc
    16261 aaactaggaa gctagttgca ggctgctcaa aacactgttt tgaggttgta gatggaagct
    16321 gacgtggttt gaagagattt tcgaagagta tagaccacaa ttactcaata ccgaataccc
    16381 ctgaatggtt tcttttacat gcaccaatat attataataa tcttcatcca ataataaggc
    16441 tgataaacta gcatcttggt caaaatataa gggaatttct cgaccgtcct tctttaatgg
    16501 atattctggt aagatactaa atagttcaat catagaagga aactcagaat tagttgttgt
    16561 aaatcgaaaa agctgcgctt tctcatcttt ctgacttcct tgatactctc ccaattctaa
    16621 aaaatgattc aaggtagtat aaaattcctt attttttact tcatcaatga tgaccatatc
    16681 ataatctttt gttgtgcgac ttttaaatcc ttgcgaatcc aatacgatag aggtagcagt
    16741 tcccccaatc agaacataat agttctgaaa atccgcaaac atttcttgaa aaataacttt
    16801 cgtattagct ggcatcatct tctcccagat actgtaatat catattttct agtgcttcac
    16861 tctcttcctc tatacgtggg tcatcatcat cttttaaggt caaataaaga gaaatcgaat
    16921 ctacaaattg tttatcatga ttatttttaa aatcattcca aaactcagat acaaaaggac
    16981 gatatttcca tatctctagc atctttcatt ttaaaacatg ctgagaaagt ggcaaggata
    17041 actgattgaa ttttctctgc catatgacat agctagtatt ttcatccgtt tcagctaaaa
    17101 aagttgaatg cgacaaagca taagcaccac catatagaag gttagaaaca gattttatct
    17161 gctttatatc gccatctggc aataaaatcc gttttttgat gggattaaat aaacatgaca
    17221 cggattttaa gaataattct ttctttgaca ccgtatatgt gtaaagctta ttttgcttgt
    17281 ttaaccaata taaagcttta aaagtcctca aacacctata aattgttgag tttggaagtc
    17341 cagtgacttg tgaaagcaaa tcaacattta ctactttttg accttttgtc aataaaaagg
    17401 caatccacgt taattgttcg ctaggtgtta attccttagg gatttcagta tcattcgcat
    17461 tgagtactag tcccaatgga gggaagaaga ggtttccctt aaagtctaca aacggaactc
    17521 tagcttgaag taattgcttt ttttcactgt ctgataactt cgaaaacacc aaaacaacat
    17581 ccatattggc tttttcaccc atagtgcgag cctgagtaac aaatgaactc aaactccccc
    17641 ttctcttttc tttaatcaat aaaaatgatt ccttatgaaa agtcatttga gtatactcaa
    17701 acctttttac aaaactgatt ggtaaagtca aagtcagttc ctcaatactg acatcaacat
    17761 aaaaggattg aaaaattgac attatctttt tgacattcat gttttttcct tattctatca
    17821 tttttattat attttatcat tcggtataat aaaatataag ttttttgata aaataaccaa
    17881 aaactactcg ctatcccctc tcacattacc ctacatatcg tttgacatgc gactgatagt
    17941 tcaggaaaac ttcaaggaga acttttctct catccactat gcaggactta ctatttcact
    18001 tctactccta taggctcaat ttgacacttt tctttttcga attgctcata tgcctcctga
    18061 atagtgagtt cgatttatcc aaatttattt ttgtctattt tgatgaatac ttccacgaag
    18121 atagtctgaa aatgaatttg caccaatttt ccttctcttt ttaagcatat tattccagat
    18181 atgattgccc tcttattcag taataaatta cgctttaaac gcttcaatca gtatatctcc
    18241 tgttgtcata tgttctaaag aaaattcttc tacatatggt ttaacatctc ttaggttatt
    18301 acttcctaat atcccattat gctttttcgc taagaaaata gaagtcgctt ctcccttacc
    18361 aataatcttg ttactatcat gatttcttgt taaatctcta tataatgcgt attcttcagt
    18421 tccaatgtct atgctcacaa tctcagctga acccttagtt accaactggt ctatcctaga
    18481 ttttaaatgg ggaattgtag gtatattgat ttcatcatac acctcttgtg gaataacaat
    18541 tttacccaaa tagagctttt ctaaaagatg ttcagtgcca acccataaaa atactgaaat
    18601 acaatctgca tcaataaata cacgactagt caaacgacaa ctcccccctc ttcatctagc
    18661 ccatatacaa tatcatatct gaaagcatct agtaacagtt cctcatactt cccttgcgaa
    18721 attctgttat tttctaaaag ttgttcagtt gaattaatat attatcctga tgccatttct
    18781 tttttacttt ctgacaaagg acgatataaa cttgtatcat agcctaatct tgaagctgtc
    18841 tctataacac taatatccat atttttaatt tcttctgcat caaggtatcc atcattcctc
    18901 aatctatata acatagcttt atgactgata ccataaaact gacccaattt tataatatct
    18961 tctacttcaa gatgagttct attggcattt tctctgattt cctcaaccat cctatacagt
    19021 gaagatggga aaattaaaaa ataagaagca aactgatccg cttttctttc agtttcatct
    19081 ccttcaccaa tcaagataag actgactgaa ctcttcttca cctcatcata ataaagatga
    19141 tacagttcat gtgctaaaga aaatctttac cttcctaatg gcatgtctga attgactgca
    19201 atgagactga actgagttcc tttataacag actccgctaa tattctttcc gagtccataa
    19261 aataccagcg tcaaattttc tatcttttgt accaatttaa aaatatctat cggcgattca
    19321 ccatcagctc ccaacttttt tctaagattt gaagctttat tacttaaatc cattcgtgat
    19381 attcctttca cctttttcca ttttggcaat catgctttga ttcaaagaca aatactcagc
    19441 aatcttatct tgagtaagat ttgaagatat tctaagttct tttattcttt ttccaacatc
    19501 acatacattt atcacataca tttatcatat tcatacacct ctcataaaaa gaatagcaca
    19561 ctcttgtcat aattttttaa ataaaaaaat tatgacaaaa caaggaagca atttattgat
    19621 gctgcttaaa aatctaaaat tgatgagttc ctatcaaaaa tcgtatcttc aacctcaaaa
    19681 cagtacttaa agctatccga ctcggtttac attgtcaaat ttagatttta tttgagcata
    19741 actttctagt ttgctttctg atttttgttt aatatagtag caaacattga aggaaatatc
    19801 tccacaaaaa aacgcatact attaagcttt ttcaagacct aataatatgc gctgttctga
    19861 tttgaaagac attccattat tattttactg taatcaagcc atctggctct actgtgaatt
    19921 ctggcttgtc tgccagtgtt ccgtctggtt tgaggtagta ccagcctgtt ccgtccgctg
    19981 actggataaa ggcatttgat accatggcgc cttctttagc gtctaagtag taccaagtgt
    20041 ccttgtactt gacccagcct gtcttcatgg caccttcttc gttgaaatag taccacttat
    20101 cagcgatttt cttccagcct gtagccattt cgcctgagtt gtcgaaccag taccagttgc
    20161 cgtctgtgtg cttcctccag cggtctgcaa gcatatagcc tgaactgtca aagtagtacc
    20221 aagtgccatt gattttctca aacttgtctt ttggataaga gccgtctgag tgtacgtacc
    20281 agtagccagt gtcattcttc tgccagcctg tttcaatcgt caagccgttc tcaatatcat
    20341 gcttaaactg ctcacggcta atgccccatt ttgccaagta agggtatgga tccacatggt
    20401 ctgagtggtt gtttggttgg ttattcgtgc aatactcgtg cgttttaatt ccagctaaac
    20461 tccctgtatc aagcgttttc ggcaaacctg cttcatctgc tagattgcgt aagagttcga
    20521 tataaaggcg gtagtccgtc atgaactctt ctttagttga atggctttca atcagttcaa
    20581 ccgctgcata ggtctcagca ttccaaccgc ccccaacgtc ccaggcacca ttatcaacag
    20641 gtcctacctg catgatgcaa ccgttcccaa caatgtgcga gaaaaaacct aattctgggt
    20701 ctttccgcca gtgataatcc gcttcattct gtacggttga atgcggattc ccagttgagt
    20761 gtgcgtgtac ttgcctatat ggttgcacgc cgacttgagg caaatctgtt cttaatttac
    20821 tcacattaat ttccatattc tactccttat caattaaaac aactcatttt ttacaatcca
    20881 gaaccagaaa ctcctttatt tctaccttac aaagaagaca attttagtca cgattaggct
    20941 tgtagataga acttcaaaac gcactatttt gacactgtaa ataggactga caaggtctgc
    21001 attctatcta caataacacc ccaaactaaa aagcttttca aaagtatatt tttacagtct
    21061 ctatatgtcc ttttcataaa tactatactt tattatatca tataaaagaa gtcaaaagtc
    21121 tgttaaacta ttttcaacac caaactaaag aagagaacac aagttttttc gattttcact
    21181 agaggaaatg gattttattc agtaaatcca actaggattg cactttggtt gccaaaattg
    21241 cctttccttc ttttatcaag ggatgacgga atagtgagaa gtacagttga actgtcatgg
    21301 caacccagat aagaggttca caaaggataa cacccttata tcctgcccaa ggaataatca
    21361 aaaccacaaa aacgattttt ccgattagtt caataaagct agaaactaga ggaaggatct
    21421 tctgccccaa gccctgcaag caattgcgat aaatcaacaa gaggctcaaa atgggataaa
    21481 aggctgaact gatttgcaga tagagacttc cattttctat caagtaacca tctgtcgaac
    21541 tagccaagaa ggaaaccaag gctggactgg caaaaaagag gaaaatacaa acaaaaactg
    21601 cccaggatat acttaaacga ctgccgattc gaagaccttg aacaatgcgg tcaggtcgct
    21661 tagctcctag attctgagaa gcaaaggtcg tcattgatgc agaaatagcg gtcataggaa
    21721 gaagggcaaa ggtcataatg cgtcgagctg ccgtctgggc actaataatc actgcaccaa
    21781 atgtattaac agaaaactgt aaaatcacac tgccgataga tacaattgaa ctcatcaagc
    21841 ccatagccaa accttgctcc aagagatccg cgtacaagct tttgtcccat ttgaaatgtt
    21901 taaaccgtgg caagagttct ggcacacttt tacgaatata ataaaagcag agaaccgctg
    21961 ataaaccttg cgaaataatg gtagcaagtc ctgcggattg aactcccaga tgcaattgcg
    22021 taataaaata gagatccaga accacattaa ccaaggcaga gaaaatcaga aatcccaggg
    22081 ctgctagact gtcaccaata gaccgcaaca agcctgcaaa aagattataa gcaaagctga
    22141 cacctacaca ggtcacaatc atagaaatat attgataaga ttgaggaaga atttctgcag
    22201 gagtatctaa gtattgcaag agaggataca agccaagaaa gcccagcaac ataactagaa
    22261 tgctcaaaag agcacctaaa atccaggtgg ctgctactgc ttccttgatt ttagtgaaat
    22321 tccgagcccc ataataacga gcaatgacaa tccccatgcc attgccaaca ccaagtgtaa
    22381 aacctacaat caggtcaaaa atcgctgtcg tcgctcctac tgcagccaag gattcttgac
    22441 caagaaatcg tccaacaatc aagacatcag cagtgttata gagctgttga aaaatatttg
    22501 atagcaagat tggaaaggtg aagcttaaga gcgagggaag aatcgaacca tgtatcaggt
    22561 ccactgttcg ttttttattc ataaagctat tatatcagct ttccagagga gcgacaagaa
    22621 acagcaaact tatatatagc ggaatgaaat aaggacagtc aaatcgattt ttaacaatgt
    22681 tttagaagta gatgtgtact attctagttt cgatctatta tagttggttg agtttggaat
    22741 agtacgctgt agctgctaaa acatttctag aaattaattt gactttccta ataaagttgt
    22801 tcatatctta tttcaagcta ctatatataa tctaaaaact tgaatcaaaa atcgaaaaag
    22861 tagcggattt ttccactgct ttaacagctt attcttcaat ttcgatttca agttcatcgc
    22921 ctaagtcaag cgtaacttct tcattcactg cttcttcttt ctttggctca tcttttttgt
    22981 tttcagtatc ttgttctgaa acttcttctc catcaatcaa gccaaattta gaacggactt
    23041 gcttatcaat ttcatcaaag atttctgggt gctctgccaa gtatttctta gcattctcag
    23101 aaccttgccc aattttttca tctttgtaag aataccaagc ccctgctttt ttgataatat
    23161 ccaaatcgct tgcaatcttc aaaagctcac cagtcttaga aattccttct ccgtacataa
    23221 tttcaactac ggcttcctta aacggtggag ctaccttatt ttttacaacc ttaatcttag
    23281 tttctttacc gacattggtt tctttttggt caccagttcc cttaatttgt gtattaccac
    23341 gaacatccaa gcggactgaa gcatagaatt tcaaagcacg tccgcccggt gttgtttctg
    23401 gatttccaaa catcactcca actttttcac gcaattggtt gataaaaatg gcaattgttt
    23461 tggttttatt gatagaggcg ccaagtttac gcatggcctg gctcatcata cgagcctgca
    23521 aaccaacatg gctatctccg atatctccat caatttccgc acgaggaaca agggcagcaa
    23581 ctgagtcgac tacgacaaga tcaactgcac ctgagtcaat caattttccc gcaatctcaa
    23641 gaccttgctc tcctgagtct ggttgagaca agagcaattc gtcaatattg acaccaaggg
    23701 ccgcagcata agctggatca agggcatgtt ccgcatcgat aaaggcagca atcccacctt
    23761 ctttttgcgc ttgtgcaact gcatgaaggg caaccgttgt cttaccagat gactctgggc
    23821 catagatttc gatgatacgt cccttaggat aaccacctga gccaagggca atgtcaagag
    23881 ctaaagaacc tgagctcatc acttgcacct tttgctccgc acgttcaccc aaacgcatga
    23941 ttgatccttt accaaagtct ttctcaatca atttaagagc gtcattcaag gccttttcac
    24001 gttctgcccc aaattttttt gaaatttctt ctaatttttt tggttttttc gccattctat
    24061 tctcctacat tctaatgatc ctcagaccta tctactatta tatcaaaagt tagtcactta
    24121 ataaagcctt gcgaactagg ttaaaggcat gcataaccgc aatgtgacgt acatctgctc
    24181 ggcttctgcc tccaatatta accttgataa cctcagttcc ttgatcttgc gccaagccta
    24241 tgaagactgt cccaactggg tgtccttcta ggctatctgg tcctgccact ccagtcaaac
    24301 taattccaaa atcagactgg gtcttgcttc gtgcctgctc agccatcttc tgagctgtaa
    24361 attcagacac cacaccatgt tcttccaaat tcttggcagg aatatccaac atccttgatt
    24421 tttcctccaa gctataggtc acaaaaccac ccttaaatat acttgaaact ccagaaaaat
    24481 tcgccacggt agcttggaaa agacctgccg tcaaactctc tgcagccgcg atggttttcc
    24541 cttgcctttt cagttcttct accacaatgc tggctaaact agtttcttcc ccataaccat
    24601 agcaaaagtc tcgtaaagaa attccttcga aagtctggca gtccaagatt tgattttcca
    24661 agatatccag cgcttgattc gcctcttctt gactgctagc ctttgttgac agacgtagag
    24721 tgacttctcc tgtcttggca taaggggcca aggtaggatc gatctgatta tcaattaaat
    24781 cagccaaaat cgtaaccaac tggctctcgc caatcccaaa gaaacgaaga actcgggaat
    24841 acagcttgct ccctgtcatc aacttgggta gaagttggtt taagaccatg ggtttcaatt
    24901 cacttggcgg acctggaagg acgacatagg tcactccgtc tacttctaat tttcctccaa
    24961 cagccagtcc tgtttcgttt ggcagtggaa tcgctccttc tacaatttga gcttgtcttt
    25021 cgttattcgg tgttcgggca tagtctggtc gcagggcaaa aaagatatcc aacttctcct
    25081 gagcctgagg atcaaagact aatgctttcc ctaaaaattt agctagggtt tgtttggtta
    25141 ggtcgtcctc agttggcccc aaaccgcctg tcaaaatcac cagactgcta cgttgactgg
    25201 caatctcaag caaagacaag agacgaactt cattgtctcc tacagccgtc tgaaaatata
    25261 catctacccc aatctcagct agtttttccg acaaaaactg ggcattggtg ttgacaatct
    25321 gtcctgtcaa aatctctgtt ccaacagcaa tgatttctgc tttcatgttt cctcctacct
    25381 atctattcgt atttttttga aaaaatcgca ggaattttcc tacgattgat ttttttattt
    25441 gtatcaaaag ttaattatct tcatcaccaa caggtgctct gccaaataaa tcttcaaata
    25501 aaaccgcatt ggtttcaagc tgagtaactt cttcttgtcc caaagaacgt cggagtatat
    25561 tttgcatttc caacatatgt gctctcgaaa caatctggta agaaacacct tgaagtatct
    25621 ctccttcacc ctgcaactgc tgagtttcaa tggttttaaa tgaatcttta tagcctagca
    25681 agttagggat actttttgca gacaaatcaa tattggtctg catattgtca ctcaaagctt
    25741 ttagaatctc ttgataatga ccaatgctat ttaaactgag agctttttcc atgacttttt
    25801 gaataacttc acgttgacgt ttttgacgac cataatcccc ctcaggatct tggtaacgca
    25861 ttcgtgcata gactagggct tcttctcccc caatatgttg ctccccaaca ccgatagaaa
    25921 tggtattaaa ttcttcttgg tcactgatag aaattgggaa acctaggata ttattgactg
    25981 taatacctcc tactgcatcc actaattttt gcaaccctct catattgacc atcacatagc
    26041 gatcaatatg gatattcatc attttttgaa tggtttctat agcaagctct gctccaccat
    26101 ctgcatatgc tgagttcagt ttcgcttcat gagcctgacc attccctgat tcaatgcgcg
    26161 tcagaatatc ccgctctaaa ctcatcattg ttgttttttt cgttttagga ttcactgtca
    26221 tcaagatcat gctatcactt ctaccgaccc aagtttcagt tcgttcaaca tttccggtgt
    26281 ccactcccat taacagaatg gttagaggtt cagtcgcttc aataaccttg gtttcttcgc
    26341 cgattttttt ataggtttta gctaaggttt ctgtcccttg ttgataaata gtataagcaa
    26401 aaacacctac tcctactaca gttacagaaa gtaaagctag caccattcca ataatttttt
    26461 taaccatatt tctactaacc tatcagttta cccatcaagt aaacatcgat aaatttccct
    26521 tcttctatat atgccccacg ctcttggcta ccttcaatga caaagccatg cttttgataa
    26581 agatggactg ctgcttgatt acgagtttgg acagtcagtt ggagacgacg cagaatgcca
    26641 cttgcttgtg cccactctat cgcttcttct agcaacaaac ttcccaagcc attattccaa
    26701 tatctttttc caatcacaat gaagagatct ccaatatgac ggactctctt acgctgatca
    26761 gctgtaatat ttacaatacc agcaattttg ccatttaaga atgcaagtaa ggttatctga
    26821 ttgtccgaac tagcttgctt gttgaggaat atttccatct cctcactagt caagagaata
    26881 ccatctccgt ctaggctggt aaagtctgtc tccaaactca cacgatttaa aaaggccact
    26941 aattcagctg catctttggg ctctgcttcc ctaatgagca attcatactc catattgaag
    27001 ctcctctgac aatttctcag cacgcaaacc ctttgcctga aaatttaaac ggcgtccatc
    27061 tgcttctttt agaatttcca attctaaata agcatctggc aaggcatctc ctaagagatt
    27121 tccccactca ataacagtca cgccgccacc aaagataaac tcatccaagt cgatagaatc
    27181 agcatctcct tcaatacgat aaacatctag gtgataaagt ggaagtcgac cttcatactc
    27241 tctcacgata gtataggtag gacttttaat catttgagaa atctgtaatc cttttgcaag
    27301 tcctttagta aaggtcgttt tacctgcacc cagttctcca attaagatta aaacatcatt
    27361 ctttgctaat agatggccca aacgctcccc taaggcttgc aactcttctt cattttttat
    27421 gtacatactc ttattatacc aaaaactttt cttttgtgtc tattttccta ctaaacttat
    27481 catcataaca tccataaaaa acaggctttc tctaaaagaa aatgagcgta acaatgacca
    27541 atacaagatc tcggaaaata tgaccataaa aggaaacttc cttcttaacc gaatttggga
    27601 caagataggc tgcaaaaaac aagcccagtc caatataaat cagaagtgag acaatggtca
    27661 ttggatttct taagaaaaga agtgttgcta aaatagtcac caacactgtc ttttttctgt
    27721 ctagcatagc aagaaaatcg cgcacgtatt ttttcaaggg taaaaaaatc agcaaatcta
    27781 gcccaaatag gaaaaagaag gatggcaata aaaagtcaac taattcttgc tgcagcgtat
    27841 ttttgatgaa caagttatct gacaaaacaa gaacagctcc taacaaatta attaagagta
    27901 acatactgta aaaaagcttc accgacttct tactggctag gacactatgg acttcttgct
    27961 tacgggtata aagataattt actccagcac agattcctga aacgaaaacc atgcttccga
    28021 tgaaaaaagc tgtactttgt ttaaaggaca agatgcattc cttccataag aaacagctac
    28081 tcaaactgat ttgaattaaa gctaacaaaa ataagattct cattgatttc atcttctctc
    28141 tcccttccta ccaatcatta tactaggaga aaagagagaa ctgtttctaa tcttctcaaa
    28201 tgtctcttta agacgctaaa caaacactag agactaatac tcaatgaaaa tcaaagatca
    28261 aactaggtag ctagccacag gttgctcaaa acactgtttt gagattgcag atagagctga
    28321 cgtgatttga agagattttc gaagaatata aatttgaaat catgaaaatc cgtcaaacgg
    28381 gtggttgttt tgtctcgcac ctcacggagc gagacggact cagagtcaca taattataag
    28441 gctgatagta ttaatctaac tatcagcctt acaggttatt taacgtttca gaaaaactat
    28501 aatgtcaaga ttaactaaac agtatctagt tccttcaaat aattttctat cttcatcaac
    28561 attaaaggat tgttataaat cttacataac tctcttgctt ctatataata atttttgact
    28621 tgttctctgt ctagaaattt ggctccagca tttcctacaa gaataagtag aggagccaat
    28681 tggtagcttg tctgtctttg tttacagagt tcaatcgttt caagagcttc ttggatggct
    28741 tcattatatt tttcctttga tactaggtag tgagcgtagt tgtaacgaac tctgatgtag
    28801 ccaaataaaa actcttgatg gtccaaattt tttgtctgat acaactctat taaatgagag
    28861 tagtttgcct catattcttg ttcacgaccc actaaggaat agaaattaga tagagtattc
    28921 aacgccttta aataaatcag agtatttgaa gagactttta ataatatatt ttccaatgaa
    28981 gaaattgcct cacacttact gtcatattga tagaagtcaa taatagcttt aatccattca
    29041 aggtaagttc ggtcttctag tgttagaaaa gtacttcgtt caatctctat tctataaata
    29101 tattccaaat cgtcataatt tctatcgtct aatagtcgag cagacaattg cttgaaatta
    29161 gagaggttag atttaatttc aatttgttca ttaaaaaaat aatctaatgg tacttcaagt
    29221 cgttgagaga gtttgaacaa aaggtctgcg gagggaatga aatgccctct ctcaatttta
    29281 ctaatctggc tttgttcaca aattccttct gcaagagttt gttgggagag tctcaactct
    29341 tttcttttca atctgaattt ctctgcgagt gtactcatta aagataataa accttcctat
    29401 ttgcttaatt gcattataaa atttttagtt caaaatagca agttaaagaa ataaataatt
    29461 ctttatggta ataaactaaa aaaagtcaaa aattacataa aaatgcttga ccgaataata
    29521 tatatatatt aaaataaaaa caaggaaaaa gaaaggggtt tcattgcatg agaaaaaaac
    29581 gtggaattaa aaaattagtt acatttgatg cgggatggta aagaataatt gaagaagatt
    29641 cttttatcaa tagtttagta agcttgttag tttatagagg gcaggggtat ttctgccctc
    29701 tgttttagaa taaggaatgc actatgaaaa aattatttat actcatatcc aacctgcttg
    29761 ctagtttgtt ctttgtttgg gtatttacca tttggactga tacatatgtc tcccattatt
    29821 accccaacgt tgttgtacgt gattcttccc ctgaaacaac ttttcagcat gttgctacac
    29881 gcttggaaaa actagcagaa gaaacagata gctttattgc gattcaacac caagattcta
    29941 actcagaagg tactacagtt ttttcttata cgacctttgg ggacggaaag ttgcctgatg
    30001 ggcttcagga aaaaaaacta gaagatgctc aaagtagtag tgttgaaaca aactattttg
    30061 tattcgatgg acacctagat attcacttgc taagggagga gctaagtcaa cttggcttga
    30121 ctaacatgaa cctgacaatt ccatctaaac tatctacgtt aatggctatc tttagtaacg
    30181 gatttcagtt aatcagtcta ttgattttca tcttaacctt tgtagcactg actttaatta
    30241 gtcaaattag ccaattacgg tcgtcgggca ttcgcctcat ttcaggagag aaacggtggt
    30301 ccattttcct tagaccagtt ggtgaggatt tgaaagggat agctgttggt ttcagtttag
    30361 ctggcgtgct cgccattctt atgcaaaaaa ttctgtcgct tccaacgcaa tccctaatga
    30421 ccataggagc aggcttgctc agttataatc tcatcttgtt gtcgatctcc ctgtttttcg
    30481 ctcaactctt cgcagttggg ataaaaaaga tacacctgat gcagattata aaagggcaag
    30541 tgcctgtcag aggaatcatt agtttgattt taatcggtca actattagcg attattattg
    30601 taacgctggg aatagggagt agcttaaagt attcccaagc ctggcaacag catcggattg
    30661 gacaagaggc ttggagtcag gaaaggcaac tgattaccct atcaatcagc cgtgaaggaa
    30721 cgagtcctgg ttttgatgaa caagctcaaa ggaaactcag aacttggtat caattgatgg
    30781 atctggctgt ttcagaacaa aaggctttct tatctagaca ccagttaatt gaccgtactt
    30841 tgcaaaatgg catggcttcc tccaaaaact tgataacctc tacagaatgg cacgattaca
    30901 acccgaatgg caatgtcctt atcgtcacac cgcaatactt ggagcgtcaa aacattcctg
    30961 tagatacaac tattgagcaa aagatgaatc accttaatgt aggggagttt gtcttattgc
    31021 tgcctgaaca cctccgttca gaggaagaac attataaatc tgtttttgaa gacgacttaa
    31081 ccagtcgcat gtctagtcaa gatgaacgac agcaaatgac tgctacggta ggttatttag
    31141 aatcaggtca ggatcgtttt gtgtataata cgacccctat ttcttaccag cagtttttga
    31201 aagatccaat catcattgtt ataacacccc aatcaactgg tccacagtcc attttgtttt
    31261 ggatagacgc agtacagaac tacgttctct ttaatcaatt gtctgatgcc caggagctta
    31321 tccagagaca aggcattgaa aattgggtct cagaaatgca aacaggttac cacaactaca
    31381 tcacattatt ggataatatc cagagggaac gttgggtaat gctagcagga gctgtgcttg
    31441 ggattgcaac ttcaatcttg ttgtttaaca ctatgaatag gctctacttt gaagaattta
    31501 gacgtgccat ttttatcaaa cgcattgcag gtctcaggtt cttagaaatc catcgcactt
    31561 atctctttgc tcaactgggt gtgtttttac tgggatttgt tgcgagtgta tttcttcagg
    31621 tagagatagg agttgctttc ttagtcttgt tactctttac tggtctatct cttttacagt
    31681 tacatgtcca aatgcagaaa gaaaacaaga tgtccatgct tgttttgaag ggaggttaat
    31741 atgattgaac ttaaacaggt gagtaaatct tttggagaac gagagttatt ttcgaatctt
    31801 tcaatgacat ttgaggctgg aaaagtctat gccttaattg gttcaagtgg tagcggaaaa
    31861 acaaccttga tgaacatgat tgggaaatta gaaccttatg atgggacgat tttttaccga
    31921 ggtaaagact tggccaatta taaatcgagt gattttttcc gtcacgaatt gggctacctc
    31981 ttccagaact ttggcttaat tgaaaaccaa agtattgaag aaaaccttaa gctaggtctc
    32041 attggtcaaa agttgagtcg gtcggaacag cggttgaggc agaagcaggc tttagaacag
    32101 gtcggcctgg cttatcttga cctagataag cgcatctttg agttatcggg cggagaatcg
    32161 caacgggttg ccttggcaaa aattatctta aagaatccac cctttattct ggcagatgag
    32221 ccaacagctt caatagaccc agcaacctct cagttgatta tggagatttt gctatctctt
    32281 cgagatgata ataggctaat cattatcgca acacataatc cggcaatttg ggagatggct
    32341 gatgaagtgt tcacgatgga tcatctgaaa taaaaatcct tgtttttaat tgcacgatga
    32401 gttactgaaa tattatcatg aatcaagaat tggagttaat ttagaattgt actttattaa
    32461 tattgaggta actttttctt gataaaggag gaaatagtgg agaggaagtt agaatgaaaa
    32521 aattcgacaa ttatattatt gagaagcctt gcgattctaa ttcagataaa ctgcaaaaaa
    32581 tcttaataat tgaaaatttg gtagatgata ttttgcaatt tcctctcaga atcaataata
    32641 gtgtaggaga gattttcctc ctacaaccgt ttcaaaagaa aactatcttt attccatgtt
    32701 attttgagga agatattgtg aaagtcaaag atgatgataa agttgagtgg aatttgttag
    32761 aatttcaaaa atttagagca tttttggctt agtaatctgt gttgaaggct caaaacctat
    32821 ggtaaaaaag tcgctttgaa aacgtattgc ctccaaagat ttagttaaat aatgatttaa
    32881 cacaaaaaga aattattgaa gttctggaaa gatgttgttt cagtattgag aaaaggtggg
    32941 aaaaacttgc gattttcaca gagaaaggaa gaaaaagtat agaaatatag tcaattgaaa
    33001 caagaacagg acaaaagaac cttttgtgcc atatttttct cctttcgctt tacaattggc
    33061 ttgaacacct ttattgtatc gcgtttggag tttttttggt ataaccttcg acgcgcaccc
    33121 gcatagcggg tgtttttttg tctcgcacct aacggagcga gacgaactaa tagtcactta
    33181 atcaaaaaac gcaccatatc aaaaactaaa aagtttgata tcatgcgtca tgtcttaaac
    33241 taattgacta tactttctat tcaaatgagc ttttaaccaa ttgattgagc caatccactc
    33301 ttaaaaccaa agagcaattt ctcgcttagc tgactcttct gaatctgaac catgtacaac
    33361 attttggata acctcatttt ctccagcagc ttttgcaaag tcacctcgaa tagtgcctgg
    33421 taaagcttct tctggacgag ttgcacccat catggtccgc caagtttcga ttactttggg
    33481 accagaaatg acacccacaa gaactggacc tgaagtcatg aattcacgaa tcggtaggta
    33541 aaaactctga ccaaccaagt cctgatagtg ctggtcaatc aactcttctg aaacctgtga
    33601 acgaaactcc aatttttcga ttgtaaatcc acgttgttcg atgcgcttta acacttcacc
    33661 cactagccct ctttttacac catctggttt gatgataaag aatgtttgtt ccatacccgt
    33721 ctcctttgtc agcttctttc ttttatttta ccacatttcg tggaaaaatg gagaaagttt
    33781 tcagaagaga gaatgagaga acccgagggt tctctcattc tctcttattc tactgtttct
    33841 tccacagttt caacggcagt atccacaact acttctgttg tttcttcatt tccttcttcc
    33901 tctactggag gattaaggta ttcttcttcg ttgacagcat gtggttcaag gttacggtaa
    33961 cgggccatac cagtaccagc tgggatgatc ttaccgatga taacattttc tttaagtcca
    34021 aggagatggt ctttcttacc acggatagct gcgtcagtaa ggacacgagt tgtttcttgg
    34081 aaggaagctg ctgacaagaa actgtttgtt tcaagtgagg ctttggtaat tcccataagg
    34141 actgggcgac ctgtcgctgg aactccacct gcgataagga catctttgtt ggcatctgta
    34201 aagtcattga tatccatgag ggtacccatg agaagatctg tatcacctgg atccatgaca
    34261 cggactttac ggatcatttg acgaaccatt acctcgatgt gtttgtcacc gatttctacc
    34321 ccttggctac ggtaaacttt ttgtacttca ccgagaaggt acgtttcaac tgacaagaca
    34381 tcacgaactg caaggagacg ttttggttgg atagaacctt ctgtcagagc agcaccacgc
    34441 gctacttggc ccccaacttc gacacgcata cgagctgtaa atggaacgac atattcacct
    34501 tcgccagttt cacccttaac aaagactttc ttggtacgag ttgatgcatc ttcttcgata
    34561 gcagtaactt gtcctttaac ctctgtgata accgcttccc ctttaggatt acgggcttca
    34621 aagatttctt ggacacgagg aagaccctga gtgatatcgg tatttgaggc aaccccacct
    34681 gtgtggaagg tacgcattgt aagctgtgta ccaggttccc cgatagattg ggcagcaatt
    34741 gtaccaactg cttcaccaac ttcaaccgca tcaccagtcg ccaagttgat accgtaacag
    34801 tgacggcaga caccgtgacg agtgttacat gtaaatacag aacggatagt cacttcttcc
    34861 acaccagcat tgacaatttc acgcgccttg tcttctgtaa tcaattcatt tggaccaata
    34921 atcactgcac cagtttctgg atgtttaaca gttttcttag tgtaacgacc gttgagacgc
    34981 tcttcgagag actcgatcat ctcttttcct tctgcgatag aacggatcaa gagaccacgg
    35041 tcagttccac agtcgtcctc acggatgata acgtcttggg caacgtcgac caaacgacga
    35101 gtcaagtaac ctgagtcggc tgtcttaagg gccgtatcgg tcataccttt acgagcaccg
    35161 tgagttgaga agaacatttc caataccgac aaaccttcgc ggaagtttga aaggattggc
    35221 aattccatga tacgtccatt cggagcagcc atcagaccac gcataccggc aagctgtgag
    35281 aagtttgaga tgttaccacg ggctccagag tccatcatca taacgattgg gttcttagga
    35341 tcttggttag caatcaagcg tttctcaagt ttttcacggg cagcacgcca ttcagctgta
    35401 acagcattgt aacgctcgtc gtctgtgatc ataccacgac ggaattgttt ggtgatttgt
    35461 tcgacacgtt tgtgtgattc ttcaatgatt tcagtcttgt catcaacgac tgggatatcg
    35521 gcaataccca ctgtcaatcc tgcaagagtt gagtggtggt aaccgaggtt cttcatgcgg
    35581 tcaagtaggg cagaagtttc tgtcgtacgg aaacgtttga agatttcagc gatgatattt
    35641 ccgaggtttt tcttcttgaa tggagggttg agctcaagat tgctgatagc ttccttgata
    35701 tctccaccaa gtggcaagaa gtatttagct ggaacacctt ctgtcaagtt ggcattgttt
    35761 ggttcttgca agtatggtag cccctctggc atgatatcgt tgaagagaat tttaccaact
    35821 gttgtaagca agaccttatg tctttgctct tctgtccaag gcttgttgag gctgtctgtt
    35881 gcgataccaa cacgtgagtg gaggtgaaca taaccattgc ggtaagccat aaccgcttcg
    35941 tcacggtctt tgaagaccat tccttcacct tcgcgaccag cttcttccat ggtcaagtag
    36001 tagttaccca aaaccatgtc ctgagatgga gtaactaccg gtttcccatc tttcgggttc
    36061 aagatgtgct cagcagctag catgaggata cgagcttctg cttgtgcttc ttctgaaagt
    36121 ggtacgtgga tggccatttg gtccccgtca aagtcagcat tgtaggcttc acagacaagt
    36181 gggtgcaagc gaagagcctt accatcaatc aagactggct cgaaggcttg gatacccaaa
    36241 cggtgaaggg tcggtgcgcg gttcaaaagc actgggtgtt ctttaatcac ttcttcaagg
    36301 atatcccaga tacgctcatc tccgcgttcc accaagcgtt tagctgcttt gacgttttgc
    36361 acgatatcac gggcaacgat ttcacgcatg acaaatggtt taaagagttc aatcgccatt
    36421 tcacgtggca caccacattg gtacatctta agagttggac caacggcgat aacggaacgt
    36481 cctgagaagt caacacgttt accgagcaag ttttgacgga agcgtccttg tttaccttta
    36541 agcatgtggc tcaatgattt caatggacgg ctacctggtc ctgtgattgg acgaccacga
    36601 cgaccattgt caatcaaagc gtcaactgct tcttgaagca tacgcttctc attttgaacg
    36661 atgatacctg gtgcatttaa ctcaagcaaa cgagccaaac ggttgttacg gttgataaca
    36721 cggcggtaaa ggtcattcaa gtcagatgag gcaaaacggc caccatccaa ctgcaacatt
    36781 ggacgaagat ctggtgggat aaccggaagg atgttaagaa tcatccattc aggtttgttt
    36841 ccagacttgt aaaaggcatc caaaacatcc aaacgacgga tggctttgac acgtttttgt
    36901 ccagtagcag ttttcaattc ttctttgagt tcagcaattt ctttttcaag atctacttgc
    36961 ttcaaaaggt cttggatggc ttccgcaccc atcttagcaa caaatgaacc ataaccatat
    37021 tcacgcaagc gctctcggta ttcgcgctct gtcatgatag acttgtgctc aagtggtgta
    37081 tccttaggat caatcaccac ataagccgca aagtagataa cttcctcgag ggcacgaggg
    37141 ctcatatcaa gggtcaagcc catacggctt ggaatcccct tgaagtacca gatgtgagat
    37201 acaggagctt tcaattcgat atgtcccata cgctcacgac gaactttcgt acgcgttact
    37261 tcaaccccac agcggtcaca aacaattcct ctgtaacgaa tgcgtttgta cttaccacaa
    37321 gcacattccc agtcttttgt aggaccaaag atcacttcat caaagagtcc ttcacgttct
    37381 ggtttcaagg tacggtaatt gattgtttca ggttttttga cttctccata agaccatgaa
    37441 cggactttac ttggagaagc tagggtgatt tgcatacttt taaaacgatt tacatcaacc
    37501 actatttctt ccctttctat tctaagtgaa ctgcttattc ttgttcagca gcttcttctg
    37561 ttgcttccgc ttttgttgct ttctcagctt cttcagcttc aaaggctgct ttagcctctt
    37621 gggctgcttt ttcgcgggct ttttcaaggt catctacgtg gatgacatct tcgtccattc
    37681 cttcatccaa gtcgcgaagt tccacttctt ggtcatcttc gtctaggaca cgcatgtcaa
    37741 gaccaagaga ttgcaattct ttgacaagaa ctcggaagga ttctggaaca cctggttttg
    37801 gaattggttt gccttttgta atagcttcat aggctttcaa acgtccgttg atatcgtcag
    37861 acttgtaagt caagatttct tgaaggacat ttgacgcacc gtaggcttca agagcccaaa
    37921 cctccatctc accgaaacgt tgtccaccaa actgagcttt acctccgagt ggttgttggg
    37981 taacagttga ataaggtccg actgaacgcg cgtgcaattt atcgtcaacc atgtggtgga
    38041 gtttgatcat gtacatgact ccaacagaaa cacggttatc aaatggttca cctgtacgtc
    38101 catcgtaaag gattgtcttg gcatcgctat ccatacctgc ttctttaaca gttgaccaaa
    38161 gatcttcaga acttgctcca tcaaagactg gtgtcgcaat gtgaatacca agagtacgag
    38221 ctgccatacc aaggtgaagc tccataacct gaccgatatt catacgtgat ggcaccccaa
    38281 gtgggttcaa catgatgtcg actggagttc cgtctggaag gtaaggcatg tcttctacag
    38341 gaacgatacg agagacaacc cctttgtttc cgtgacgtcc ggccatttta tctccgacct
    38401 taatcttacg tttttgagcg atgtaaacac gaaccaacat gttaacacct gattgcaact
    38461 catctccatt tacacgtgta aagatcttaa catcacgaac gacaccatcg gcaccgtgtg
    38521 gtacacgaag agaagtatca cgcacttcac gagacttgtc tccaaagata gcgtgcaaga
    38581 gacgttcttc agctgaaaga tctttctcac ccttaggtgt tactttacct acaagaatat
    38641 caccttcttt aacctcagca ccaatacgga taatccccat ttcgtcaagg tctttgaggg
    38701 catcttcacc aacgtttgga atttcgcgag tgatttcttc aggcccaagc tttgtatcgc
    38761 gcgtttctga ttcgtattct tcaaggtgaa cagatgtgta gacatcgtcc ttcaccaagc
    38821 gttcgctcat gataacggca tcctcgaagt tgtaaccttc ccaagtcatg taggcaacga
    38881 ttgggttttg tccaagcgcc atttctccat tttccataga aggtccgtca gcgatgaaat
    38941 cgcctttttc aacgacatca ccaactttta cgagagtgcg ttggttgtaa gcagtacctg
    39001 agtttgaacg acggaatttt tggatgtggt aaacatccaa tgaaccatct tcacgacgaa
    39061 cttctacctt gtcagcatct gcgtaagtaa ctttaccatc atactgagca atcacagccg
    39121 caccagaatc gtgggctgct tggtattcca taccagtacc aacgtaaggt gcctgaggat
    39181 taatcaatgg cacagcctga cgttgcatat tggctcccat gagggcacgg ttggagtcat
    39241 cgttttccaa gaaaggaata catgctgtcg caacggcaac tacctgtttt ggtgaaacgt
    39301 ccatgtagtc aacaatatta gctggatact cttggttgac cccttggtga cgtcccatga
    39361 caatcttctc agcaaaggtt ccatcttcat tcagacgaga gttagcctga gctacagtat
    39421 attcatcttc ttcatcagct gtcaaccaaa caatttcgtt cgtgacaaca cctgtttcac
    39481 ggtcaacctt acggtatggt gtttgaacaa aaccatattt gttcaagtgt ccgtaagatg
    39541 acaagttatt gatcaaaccg atgttaggtc cttcaggtgt ctcgattgga cacatacgac
    39601 catagtgagt gtagtgcacg tcacgtactt catatccggc acggtcacga gtcaaaccac
    39661 caggtcctaa ggctgacaaa cggcgtttgt gagacaactc agaaagcggg ttgtgttggt
    39721 ccatgaactg tgacaactgt gatgaaccaa agaattcttt aactgcagct gttacaggac
    39781 ggatattgat aatttgttgt ggtgtcaaga cttcattgtc ctgaacagac atacgttcac
    39841 ggacattacg ttccatacga gaaagtccca aacgtacttg gttggcaagc aattcaccaa
    39901 ccgcacggat acgacgattt ccaaggtggt cgatatcatc tacacggcca agtccttcag
    39961 ccaagttgag gaagtagctc atctcagcaa ggatatctgc aggagtcacc gtacgaacct
    40021 tgtcatctgg gttagcatta ccaatgatcg ttacgacgcg atctggatca gttggagcaa
    40081 caaccttgaa tttttgaaga acaacaggct cagtcacaac ggctgcatcg tttgggatgt
    40141 agacaatctt gttcaagtcg ccatccaaat ggctttcaat gctttcaatc acgctacgag
    40201 tcataatcgt accagcttct accaagattt ctccagtttc agggtctacc aatggctctg
    40261 caatggtttg gttgagcaaa cgtgttttaa cattgagttt tttattgatt ttgtaacgac
    40321 caactgctgc caagtcataa cgacgtgggt caaagaagcg agctacaagc aagctacgtg
    40381 agctttcagc cgtcttaggc tcacctggac gaaggcgttc gtaaatttct ttcaaggctt
    40441 cgtctgtacg agagtccatt ggattcttgt ggatatcttt ttcaacagtg ttgcgaacca
    40501 attcgctgtc accaaagata tcaaagattt catcatcacc tgagaaacca agagcacgaa
    40561 ccaaggttgt aaatggaatc ttacgagtac ggtcgatacg agtgtaggtg atatcttttg
    40621 agtcgctttc aagttccaac caagctccac ggttagggat aacagttgaa ccatagccca
    40681 ccttaccatt tttgtctact ttgtcgttaa agtaaacacc tggtgagcgg accaactgag
    40741 aaacgataat acgttcacca ccattgatga tgaaagtacc catttctgtc atgattggga
    40801 aatcaccaaa gaaaacttct tgggtcttga tttcgcttgt ttctttattg atcaaacgga
    40861 aggttacaaa aattggtgct gagtagctag catcgtggat acgagcttct tctagcgtat
    40921 attttggttc cttgatttca tatccaacaa attccaactc cattgtgtct gtgaagtttg
    40981 aaattggcaa tacatcttca aacacttcct taagaccgtg gtctaggaaa gctttgaatg
    41041 agtcagtttg aatttcaatc aaatttggta agtcaagaac ttctttgatt cttgaaaaac
    41101 tacgacgggt acgatgtttc ccgtattgaa cgtcatgtcc tgccaagatg attctccttt
    41161 gtaaataagt tccaagcctt gtcaatcagg cttttctaat cgtcatatgg ttgtaaaccc
    41221 cttatcaccg tgtcctcttg acgaattttc agaatcttta agcctctgtt acaaatgctc
    41281 aaaatcttga aaaaaagcac aaaaagagca gctaaatctg actttttcag aagatttaac
    41341 tgctgtgagc cttgtctgga caatatttca gacaaaacct acgacaaatg attacccata
    41401 ttatacccta tttagctaga tttttcaagg ggtttcagta ggtttttggt aaattttttc
    41461 ccatagaaaa cttggcatca cattcgaatc acgctatggt acaaaaaact gaaaaaacta
    41521 ttgactgaaa atcattttca aggtataata ataaacgtta aggcggtata gccaagtggt
    41581 aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc cttctataac
    41641 ttgatttatc aggtttcaaa tgaacagaaa gcccaatttg aagggctttt tttattttcc
    41701 ctcgaataaa tacgtataac tttaaaaact tttggagcga gtttgtggca gagttctttc
    41761 catggcataa ttcccttttg aaatcaattg aaaaaagctt cgtcacgcct ggtgacaaaa
    41821 gcctctagtt tattctgttt cttcttctat ttcgacttct gtgatttgga cttttacctt
    41881 ggtaacacgt ccattcttca ctttatcatt ggttaagata aactgtttgt tttggctgac
    41941 caattcatag ctgagtttct cagtcgttgg aatggttccc actcctgtca aataataacc
    42001 agcgatggta tcaacgtcat cactttccag ttcaacatca aagtaattat tgaaatcatt
    42061 gagggtcata gttccttgaa caatgtaggt atcctcgcca atctgatgaa catctattgc
    42121 tgctttgtcc gtttcatcat caatttcacc aacaatttcc tctaagaggt cttccaaagt
    42181 caccaaacca gccataccac cgtattcatc cagcaagatt gccatttgtc tttgggtatt
    42241 tcgcagttct tttagcaagt catccacaaa aatagtttca ggtacaaaaa gtggatcttg
    42301 taaaattctc ttccaaacaa tattgtcaaa accgtccaca aagcctgcct taaggagact
    42361 cttggtgtga atgattccaa ttacattgtc cttatcccca tcataaaccg ggatacgaga
    42421 ataattttgt tttaaaatac tttggataat ggcttgacta tcatcctgaa tatccaccat
    42481 aaaggcatcc gttcgaggaa ccataacctc tcgtgccatc agttcatcga gcgaaaagac
    42541 accttgtagc atctcaatct catcagcatc caatgtttct tcactatttg tcagcatata
    42601 ggcaatttca tcacgggtca tcttttcatc cgcatcatcg aatgacatag gagtcaaatg
    42661 gctcaagaaa ttggtcgaag cagctaaaag ccaaacaaaa ggactgacta gttttccgat
    42721 cccaatgata atcggcgctg tacgaattgc caaggcatcc tttagattaa gagcgattct
    42781 cttaggatat aattccccaa aaacgatgga aatataggtc aaaaatgcca aggatagaaa
    42841 agttgccacg gcttgtgctg tttcgccatt cccaagccaa gaggcaatca cacgtcctag
    42901 agtatcagtt aaactcgccc ctgataagat tgtaatcagg gtgattccta cctgaatggt
    42961 tgataaaaag tggttaggat tttctagtac cttcagcagg cggatgtagc gtctgtctcc
    43021 ttcttccgcc ttttgttcaa ctcgggcacg attaagagaa accatggcca tttctgtggc
    43081 tgagaaaaag gcatttaata ccgtcaagat aaacaataaa acaaattgta gcaacaaatt
    43141 ctgactactt gggtcttcca tagttcttct cctaaaatag tatcttatcc tttattatat
    43201 cacaaaattt aatccaatac atattatttt tttcttagcg taacttccat ctctctccca
    43261 aaactggaag ttagtctaag acggatttcc actgatttca cgcgtttttc tcatactaaa
    43321 agctaggttg tgggaaactg gaagttagtt ttagaagtta ctatttttta ttagtacctg
    43381 ttctagccct gcttaaacta gtaaaaagaa ctcctacatc cataagtgac ataggagttt
    43441 aggcttatct tttactgagt tacagttact tctccagttc ggtaatccag ttgaagtccc
    43501 ttttgaacat tgggaactag aacattgaat tccaattctc catccgaaga cttggcttca
    43561 atctgtgaag ctgagggaac taaatcctcg tttgaagcgt agtaaagggt tacacggtaa
    43621 cggacacgct tgttttggtc caaggcttta cgcaccttgc tttcatagta gttttgacca
    43681 gtcgaatact cggcttgtgc ctgatttgcc caggctgtct gaacagcaat gtttttagga
    43741 ttgcttgttg aggcatcaaa accatccaaa ccaccgatta aggcatagcc taacaaatga
    43801 cctctatcga ctgcatgggt ataagagccc tttagattct tgacctgatg ccaacctgga
    43861 ggagtccaag aagttgaacc attcccagtt tctttacgat tcttgtactg acgagtggcc
    43921 ttagacaaga gggcattagc tacggttgga acagtttcct tgcccactgt ctttgtttta
    43981 ttgtcagcgt agggcttact tgaaaccttg gcatctagat ttgttttatt accattgacg
    44041 ataaaagcac ctgagccatt ccactccaga ctccccttta tttgactctt gactgcgtct
    44101 gttaagacac tctctgccaa tgcttgacta ggagcttcag acgcttgttt tttctgacta
    44161 agattggttt tgggactatt aggtgccgac ggcatctgct tgatataata gctccctgta
    44221 gacaaaagca ataacactag cagtccgatt agtgtctgtc ttgttttttt gttcatattt
    44281 ctccttatct ttagaaaaag gctggttctc cagcctaatt tcctgtaaat ttatgaatca
    44341 attcctgcca ttttgctgga gacaggatag cccatggatc ttgacccttg cccaagattc
    44401 cataacctac cattaaaccg attcctagag ccagagtacc taaaatcagt actatgatga
    44461 ctaaaagtaa acgcttgact acgtagcttg atttcttatt catcttcatc acttgcctca
    44521 atccgctgaa tcttagcacc tagctgcgcc aacttctcat ggaaaccgta gtaacctcta
    44581 tccaagtgaa ccaatttacc gaccacagtt tctccctgtg ctaccaaacc tgtcaaaatc
    44641 aaggctgcac tggcacgaag gtcagttgaa agaacttctg ctccctgcaa aggctgtcca
    44701 ccaacaatac gagctgtatc acggataatc tcagaatgca agcccatgcg gcgcatctct
    44761 tctaggtgtt ggaaacgatt ttcgaaaact gtctccacca tggttgattc gccttttgca
    44821 actgtcatca aggctgtaaa ttgagcctgc atatctgttg gaaatcctgg gtggggcaag
    44881 gttttcacat gaacagcttt tagattttct agttgagaac gaacacgaat tccttcgtct
    44941 tcttcaatta cttcaacacc catttcaagt aacttggcaa tcaagggacg gttgtgctcc
    45001 cagacagcgt ctcgaatcaa gacatcacca ccagtcatgg cagcagctac cataaaggtt
    45061 cctgcttcga tacggtcttg gactacattg tgagtcgtac catgaagttt ctcaacacca
    45121 gtaatggtta tagtctctgt accagcacct ttgaccttgg ctcccatttc attaaggaga
    45181 atggctaagt caacaatctc aggctcacgc gcagcattct caatcactgt caccccatca
    45241 gccagagtcg ctgccatcat caagttctgc gttgcaccaa cacttggaaa gtccatatag
    45301 atatgagcgc catgcaagcg ttctgccttg gcttcgatgt aaccagctgt ctgactaatc
    45361 ttaaccccca tagcttccag acctttcaaa tgaagatcaa taggacggct accaatcgta
    45421 caaccacctg gcatggatac cttggcatga cccacacggg caaggattgg ccctaataca
    45481 acgatggagg cgcgcatctt gctgacatac ttgtaagggg cttcctcagt gatgtcgcca
    45541 gtagcatcca ccttgacaag atgagcttcc tcatcaaagt caaccttggc attcaaacca
    45601 ccaactacct gattcataat aaagacatcc gacaaaatcg gaacattctg caagacggtc
    45661 tttccttcac ttgctagaat agtcgctgcc aacaagggta agactgcatt ttttgctccc
    45721 tcgatcgtca cgcttcctac cagacgatta tcgccacctt gaaccacaat tttatccata
    45781 ctcgtttcct ttactcttga tttcataata atcctctaag cgcttcttgc cacaaatgat
    45841 acaggctaat aaagaaagaa ctcaggatgt agcctatgac aatgctaaaa aaggctacta
    45901 ataaacgaac ttttcttgta ttatcatctg tcacttttaa aaccttctcc catctaacaa
    45961 gatcctttaa aaggtaaaaa ctcacataaa taaagaacat atgactactt agagtgaata
    46021 ataattgaac catttgacta ttataccatc ttctctgttt gtgcgctagt ttggaaactt
    46081 cactcaaaaa ttagggattg tttttcaagt aatcaatcgc atcttgtagg gttttaacgg
    46141 gcacgatttt catatccgtc ttgattgttt tagccgcttc tagggctgtt tggtagttgt
    46201 tttccgcgtc cggatgcgcc ttttgttctt cttcgctaac agggttatca ggagcaaaga
    46261 aaatagcagc acctgcccta gccgaagcta caaccttctt atcaatacct ccaatgtctc
    46321 ccacattacc atcgcggtca atggtacctg taccggcaac aatacgacca ttacgaagat
    46381 ctgggtgagc tatttgagta tagatagcta gactaaacat gagaccagca cttggaccgc
    46441 caataccagc tgttgaaaag ctaattggga cattgctgat tacctctgta cggtcaatca
    46501 agccgatccc aattccattt ttgccatttt ccaaggtgat gatttttcct tctgcagact
    46561 tggtttgccc atcctcttca taggtgacct tgacggaatc ccctaatttt tgagaactga
    46621 cgtaatcaat caagtctttg gaactatcaa aggtctgatc attgactgct gtgaccgtat
    46681 cagagatatt gagaatccct ttaaaggttg aattatccgt cacattcaaa acataaactc
    46741 caaagtactt gagttcgata tccttaccag ctgtttttag tccttgatac ttggccatat
    46801 tttgcgatgt ttgcatgtag aattgattga ttcgcataaa ttcaacatcg gaagaaccac
    46861 ctgtagtctc ctgagcacta cgaatatctg taaaaggtgt caaccaagca taaatcatat
    46921 gagctaaagt ggcatgttga acaccaaccg taacgaattg ataggcacca gcttccttat
    46981 cttctgtgtc atttacttta aggacttggc gaatatcttc cgaaccacct ggaacctcta
    47041 tataataagg caagggcact acaaatgcca agaaagtcac aatcaaggcc gcaatgacgt
    47101 ataagggcca tctaatcttt tttttcattt cttatttcct ccaaaatact ctcgggaaca
    47161 tagcaggcaa tatcctgacc aaacttcaaa agctctctaa cgcctgatga actgatatag
    47221 agatgttcag gtcgactatg taaataaata gtctctatat cagaagacag ctgatgattg
    47281 tagtaatcaa aactggcttc atattgcaaa tccgacgcat tcctcaaacc acgcactaga
    47341 caagtagcac ccaatctttt tgcaacatcg accaccaatt catcatgaga agccacgact
    47401 tcaacatttt ccaaatgtcc caaagccttt tctagccccc gtttacgatt ttcaagaggg
    47461 agaaatcctt gtttgtgggg attaaaaaaa atacccacac aaagcttatc aaaaagtctg
    47521 ctcgcccgtt caatgatatc cagatgccca tttgtcatcg gatcaaatga gcctgtgaat
    47581 aagccaatct tatctgacat agactgtcac cttactaatt ccataaatct tttccttcca
    47641 gatacccaga caggcaattt cttctggaag ttcaacggcc ttatccgtct cgcacacaac
    47701 cataacatct tcagaaaaaa gctctctctc agccattttt tcaatatctg ctacgatttg
    47761 ttccttggca tagggagggt ctaagaaaac gaggtcaaat tccccagata cctgttccaa
    47821 tgccctctct gcatccatct tgaggagttg aaattttcca acttccttgg tcatctggat
    47881 attttcagcc acgatggtct gagccttacg gtctcgctcc accaaaacag cactggacat
    47941 gccacgcgat actgcttcga tagataaacc accactacct gcataaaggt ccaagactcg
    48001 tcccccttca aagtagggac caatcatgtt aaaaatggct cccctaacct tatccgaagt
    48061 aggtcttgtt gtcttgcctt ctagtgtctt gaggggacgt cccccataga ttcctgatac
    48121 gattttcata ctgtttatta taccaaatta tagacaaaaa gagaaagaaa accgaacctt
    48181 gcggttcgat tctctacaaa atattttcgt aagtatcgcg gacttcttga ggccaaacac
    48241 ttgtttgcac ttctccaatg tgtctcttgc gaagtaggaa catggccata cgagattgtc
    48301 caattcctcc accgattgtc aatgggaata ggccattcaa caaagacttg tgccattcca
    48361 attccaagcg gtcttcatca cctgtaattt ccacctgacg tctaagagtt tcttcatcta
    48421 cacgaattcc catagaagac aactcaaagg ctccacctaa agactcattc cagacaagaa
    48481 tatcaccatt tagacccttg tagccattct cagactcgct tgtccagtca tcatagtctg
    48541 gtgcacgtcc atcgtgcggt ttaccatctg gcaactcgcc accgatacca atcaaaaaga
    48601 cggctccaaa ttctttacaa atcgcatttt cacgttcttt cggtgtcaag tctgggtagc
    48661 gttctaccaa ttcttctgta tggataaagg tgatttgttt tggcaagata gactcgatgt
    48721 catagcgggc ttcaacagct agctcagtca ggcgaatagc cttataaatc ttctcaactg
    48781 tttcttttag ataaacgatg ttacgcttac catttgggat aaccttctcc cagtcccact
    48841 ggtcaacata aacagagtgg gttgcatcca aggaatcctc atctggacga agggctttca
    48901 tgtggacaaa gagaccctct ccttcaccaa agccaaaacg agccaaggtg tggcgtttcc
    48961 atttagcaag tgagtgcacc acttcataag tagcatcagg gatttggaga accttgaccg
    49021 atactggatt ttccacacca gacaggttgt cctgcattcc gtcaccgacc ttactcaaga
    49081 taggaccttg aacttcgaca acttctagct tatctttcaa atactgggta aaagtgtttt
    49141 tgacaaagga aatttcttct tgttgatgga taaaactttt cttcatagac aactcctcaa
    49201 aaatttaata aacgtattat acacctattt ccaagaaaag aaaagagaaa atttaaaaaa
    49261 aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga ccaaagatac
    49321 gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc attgacacca
    49381 cccagcctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc ttttggttat
    49441 cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata taatcaaaga
    49501 agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg agagctgcca
    49561 tcattgctcg accaatccca ctcaagtctt tcttggtaaa aataccaact gccgccatga
    49621 caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga gtatagaaag
    49681 ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat actggaagag
    49741 cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc aactccgcaa
    49801 aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa gtaaaccaac tgagactgaa
    49861 agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga ccaacaaagg
    49921 cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata gtgtgattca
    49981 tccatttctc cttttctgtg aacatctttc cttgattata acaaaaaaag ttaaaattag
    50041 cttaaatgga agattaaaat accggctgca accgcaacat tcaaactctc ggcctgcccc
    50101 ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact aattccttga
    50161 ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct gtaatcaaca
    50221 gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt ttcgtcaaga
    50281 agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg catggaacgt
    50341 agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc tgtaaaacct
    50401 gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac atcttccaaa
    50461 aacaagaact tgccctgact caaatcagct tgtcctactt cttctttttg aaccacggca
    50521 acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc tgaaatccag
    50581 acagtttgcg gaaaagcagc taactgattt cgataatttt ctagggcaaa gattttctca
    50641 atcgtcactc cagcttggac agcttcttca aacaagtgcc agccttcaat caaataggca
    50701 gacttgcggt attttttttg gtgtaatttc ttggcatttt ttaccacaga attggctttt
    50761 gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt atgcaaaagg
    50821 ttagaatgat tgcccaaggt agggtacagg gagtcggctt tcgttggggt gtttacagct
    50881 tggcacttga aattggtggc atcacaggtc gagtatggaa taacgacgat ggcacagtgg
    50941 aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa gaaatccgaa
    51001 aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc aactttcctc
    51061 cctactctga ttttaaaatc gcaaattagg tctccagaac tattgtatat tttgtaaaaa
    51121 aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga aatctattaa
    51181 acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg gctgtgtcaa
    51241 tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg gagcgcctat
    51301 ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg tcgctatcat
    51361 tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc aatcatggaa
    51421 ggcaacgctt cactctgaaa agatgaacgc tctcaagcat gtccttgagc cacaccaaac
    51481 acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa gcccaacaag ccctctttgc
    51541 cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta ggatgtttcc ctatcctcct
    51601 tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag gggttgctca
    51661 agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg cctgtgctgg
    51721 tgtcctttac tatcttcaat cgctcctttc acttcacgga gtagaagatg aaatgcaaag
    51781 agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct tctccctctt
    51841 ctcaccagct agtgtcacac tttactgggt tgtcggtggt ttcatgatga ttctccaaca
    51901 gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg aagaactagc
    51961 caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag acgttacccc
    52021 tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg ctggaaaaca
    52081 acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg caaatcaaaa
    52141 gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat aatcttgata
    52201 actttcggta tccatgagtt ttttagcgtt cttgacgcga tctgctgttg gtggtttgac
    52261 tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca tggtgtgata
    52321 aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac caagttcaat
    52381 caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc agacaggttt
    52441 tccaatatct gatagatact gggcacaagc caagatattt ttattagttt gtctagtgac
    52501 aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt cagtgacagc
    52561 catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa gagcacaggt
    52621 atccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa tcaggaaatc
    52681 aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc cccagaaacc
    52741 acggtagcgc aaagcctctg tcaagacatc atctaccgtc cgttcacgtg acttattgga
    52801 ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac agccctgcaa
    52861 aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg tcgaatgcac
    52921 cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac cttccttgaa
    52981 aacgttttat agttttatta tatcacgact tgaaggaaaa acaagatttt tgcctatttt
    53041 ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta ttcttcaaaa
    53101 tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg gatttgacgg
    53161 gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt atactggtag
    53221 cccattgaaa atccgtgggc acctgtatca tgaattacca gcaaatcacc gatttctgta
    53281 tgaggcagtt cgcgattgac tgcaaattta tcattgtttt cacagagtga accaaccaca
    53341 tctaccgctt cagctggtcc atctggatgg gtcacgttgc taatatgatg gtaagctccg
    53401 tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata ggtacggtag
    53461 gtttccttct tatgagtcac tcttgtgact agagcaccgt gaggtgccag cataaaacga
    53521 cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac ttcttcatac
    53581 accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc tggacgataa
    53641 ttaacaccaa taccgccaga aagattgata aagtctagcc aaatgcccaa cttttccttg
    53701 atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag atgggtcacg
    53761 gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc cttcaagata
    53821 gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc aggattgtcc
    53881 ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga gatgatttct
    53941 ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa gttaatggtc
    54001 gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga agagaacata
    54061 atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa gctctacata actagagcag
    54121 tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg agtagcctta
    54181 actgcaaaat attccttaaa gcccttgttc cacgaaaagg cttggttgac ggctcttgcc
    54241 ttctcacgaa tccccttctc atcatacaag tgaaagggag tcgggaactc ggcaacaatc
    54301 gcttctaact cttctctatt aataaatggt gttttcataa gcttccttct attctatttg
    54361 aaaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt atcttcgtca
    54421 aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt ggttaccttc
    54481 aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc cgcaaagacc
    54541 gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc gttgaccgtt
    54601 ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt aagactacgt
    54661 tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata gttgacgcta
    54721 acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga gacattgagg
    54781 acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat aaccgcgtca
    54841 attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa gatggctggt
    54901 gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc actttctgac
    54961 aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat agacggtgtg
    55021 aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc aatttcctca
    55081 aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga ctcatacttt
    55141 tcagcaaaag tattgagact agttagttta taaggattat taatcaaata gttggaaatg
    55201 acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat ttttattcaa
    55261 aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg ttttgagatt
    55321 gtcgatagaa ctgacaaacc ctgtaatata cctgcatata tacatacgac aaagcgatac
    55381 taccctagtt tgaagagatt ttcgaagagt attcattttt gtcttttact tattatacca
    55441 tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc ttaaattatc
    55501 aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta ttggacatct
    55561 ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca tccagattgt
    55621 caatcatatg gataatctct gcctccataa tacgtggacg gactggactt ccatattcaa
    55681 gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc ttggtatcat
    55741 cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg atatgtccaa
    55801 gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg ataaccttag
    55861 ctaagtcatg cagcataatc cccgcataga gtaagctctt attgagctga ggataaactt
    55921 cgctaatagc gtctgccaaa cgtaccatgg tcgccgtatg ataagccaag cccgtttcaa
    55981 aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca tacttggtgt
    56041 agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc atttgcgaca
    56101 tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatcg gctgggtcat
    56161 tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg gtattgttat
    56221 aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc tcaatgttat
    56281 gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg aaggtaaagg
    56341 ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt aggtaaaagc
    56401 cttcaaatag ctcatctttt ttcatgtgac taatcttcat attcttcctc attttcttga
    56461 aaatggagta gatcaagcgc aggctcgcct tctgacaact caatgtgacg gagcgtccgc
    56521 tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc atgttggaga
    56581 tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt gacactggca
    56641 agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa accaactgat
    56701 agggagttaa gaagggctga tagggtactt ggtcctgcaa cgataatctg ttcttcccgt
    56761 ctcaaatcat caaagaagac cggattgcgg acgatttctg agtagagacc ttctgtcgga
    56821 acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta tgtacttgtt cctaatatcc
    56881 ctagcaaaac gcttgacact tgctaggagt gacttacgac agcgttcgat ttcatccttg
    56941 tcacctactt cataggcttc ttctaagcgg taataatctg ccagtggaaa cttagagtca
    57001 attggtaggt agacgtattc ttggtcgcct tgtccgggta acttgatggc atactccact
    57061 cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg tgtcatgatg
    57121 tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt ggttccagag
    57181 agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc aagaccacga
    57241 ttgacagact ccagttgttt agaaactgtc tcaaaggaag cctgtaagcg tgtctgcaag
    57301 gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg ctcatttgat
    57361 tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag attatctgtc
    57421 atttcttgac ggacttgggt caggccttgg tgcaattcaa tccgcacttc ttgcaaacgg
    57481 tcgctgacag ccacttccaa atctttttgg tctaactggc tggcttgtct ggcttggtca
    57541 aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct cttacttaag
    57601 tgtttctcct gcctatcctg cctttgccaa atcagaaaaa gaccagctag gttggcaatt
    57661 aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca gtacgaccac
    57721 ataaccatct gggcaagtta ccgacacttc cctatctata tattcgttag aagcgtacac
    57781 ttttttaaag aaaaaatttt cctctgtcaa ctcatacttg gctccaagaa tagtcagctg
    57841 gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt ctagctgact
    57901 ggtcccttct ggacaataag taatcaagtt ttgcccatcc tcaatttcta tttgatgcat
    57961 atagggtgcc aacttaggat tgctaggcag aaagacattg gccaacatat ggtcaatacg
    58021 gccacccaag gcaccgaaaa tagtaacctg agcctgagga tttttctcaa agatggttaa
    58081 gagagccaat tccaaatcgg tatcatcttt ttctggtcgg gcttggacaa aatgctgggc
    58141 acctttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatccc caactgctag
    58201 agcaagaagc aagtcttctt ccaagaccca gagcgagcct cgatccaccc caacaaaagc
    58261 atcaaaatct gtccgataat gaccgcggtc tccgcctgca aaaacggcaa ccctagtcca
    58321 gttgttttct gagagtttgt actcgctcat tgacatctcc cttaaagaca taggaacctg
    58381 ctacaaaaac ggtcgcacca gcttctttgg cttgggcaat agtttggtca tcaatcccac
    58441 catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc aactcacgaa
    58501 ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta accgtcatga
    58561 ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactgat gtgccaggat
    58621 tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg ccatgaatat
    58681 gaggcgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca aaatcttcca
    58741 gatgatgctc agggtttgac accatcaagt ggcaatcgaa aaccatctta ctatgaggac
    58801 gaaggctctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga ctgtccatga
    58861 tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca cgttcaaagt
    58921 tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata ggtttctcct
    58981 tattttggaa tttttttgct gactttttta taggtttctc tacgattttc aatttcacta
    59041 aggaattgca ggtaattatc aaaacggaag gttgcaataa caccctcttc aacagctggt
    59101 ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca atctcggcta
    59161 acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac ttcatagtcc
    59221 aaggatgaaa atcctggtgt atctgcgatt ttacccccgt tgagattgta aaaactaaca
    59281 gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt ttcaagattg
    59341 aggtctggta cgagtttatt gagaagagtt gacttcccaa cacctgtctg ccccataaag
    59401 accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac aaagtcatag
    59461 ccgatgtcac cataggtctg ccggtaaaaa tccagttctc ccctatcttc caacaaatcc
    59521 attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac caagaaacga
    59581 tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac agcttgatcg
    59641 atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt taggatatag
    59701 ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg ggtatggcct
    59761 tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact ctccacatag
    59821 tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt gccctttaag
    59881 tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca cacttggtga
    59941 caagcctgcc tggttcaaag ccttggtcag cttgtccttg acctcttcag tcttaccaaa
    60001 gtaacctgtc aagttattcc acaaggtctt acggcgatgg ataaaactag ccttggaaac
    60061 cttaaagaag aagttctcat cttccactgc tacagctggc tctggacggc gcaccatttt
    60121 caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca cgataaaggc
    60181 aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag ccttggtgtt
    60241 aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa actcactaaa
    60301 aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt aaggcaaatt
    60361 agccactacc ttgattggca ggttaggatt tttaaaattt tggatatgtt gcgccaaatc
    60421 aaccttgaga atatcttcgt taactacggt cacattatca aaatcacgca gagtatctgc
    60481 caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg cacgctcagc
    60541 caaaaattct gtcaaggcac caatacctgg cccgatttcg atgacattga cctgatcatc
    60601 aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcaaga aattttgccc
    60661 aaaggacttt ttaaaggtaa aaccgtgacg ctccaacact gccttggtca cgctataatc
    60721 tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac acattcccct
    60781 tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag aaagatagtc
    60841 ttggaaatct ttaaagaggg acttagcgct tctctcgaaa catacgttca tactcttcga
    60901 aaatctcttc aaaccacgtc agcttcacct tgccgtactc aagtacagcc tgcggctagc
    60961 ttcctagttt gctctttgat tttcattgag tatcaaaaaa atcagcttct tgataacttc
    61021 gattttcggg tagggtcaaa tccacatcct cctccacatc atccactgtc agttcaaccg
    61081 tctgaggtaa atttttcaaa cgataatgct tttgcctttg cccttcaata ctagcaaaat
    61141 caagcaaata gccatgcact cggatttgaa ccaaaaggag atgattggtc atattttcca
    61201 tgatgaggat atcttctaaa ccacctctgg cactaggata atcagatacc ctgcgaatac
    61261 ggattttttc acacatgagc aagtttcctc atatcaatga tttcatcagc cttattccag
    61321 actaggggat tatgggtcgc aatgatgata attcgatttt catctttcaa atccaccaag
    61381 agattcatag cctcctctga attttcagga tcaagagctg ctgttggttc atctgccaaa
    61441 atcaagggtg gatttttcaa aatagtctta gcaagggcaa ctcgttgggc ctctccccca
    61501 gataaagtat agattttttg ttctaaatcc aaatacccta gattaacttt ttctaaagcc
    61561 cccacttgcc tttccaaacg ttctactttt gagattttct gaccaacaaa acccaaatcc
    61621 aaattttctt tgattgattg gttttctaag aggccgaaat tttgaaagag atagcccatc
    61681 tggtctcgaa aatactcacg agtgggaatg gtttttaaat ctttcccctg atagagaacc
    61741 cttccaccat ctatcttttc tagctttccc aagatattca gcagcgtcgt ctttccactt
    61801 ccactctttc cgattaaggc ataaaccttg cccttctcca gcttgagatt caaaccagag
    61861 aaaatcgcgc ggtcattaaa tttcttttcc aatccttgaa tatcaatcat cttattttcc
    61921 tttcaatact gccatgctac cagcttcttc ttttttgtcc tgccttacta aaatcaagag
    61981 ggcgttaagc gtaaacaaag ctacaactag agcgctaatc aaaccatctc ttgtcaaaat
    62041 actagatagg actaggccaa gcaagagaac tcctccttgc gccagtaaat acttgccatg
    62101 aagctcatag attgtcatac cagcaagacg tttaatcata agatcccgtc tgaactgctc
    62161 aaaatagaga agattcatgg aatcaaataa caagatagcc gtagacaggg tcaaaatcgt
    62221 cccaataagg agagagtaaa actccacccg tttgtcattt agtaccttgg caaaaaatag
    62281 ctggcttttt accaagtaag aaaccttgtg atacagacct tgctctttta gagctgtgat
    62341 gctgtctcca tatcgatcta gtttcaaggc actattagcc gtagttcccc acaacatccc
    62401 tgcaacaggt cttgctccag tcgcttgcgg cgttagaact acaataatcg gatcttttag
    62461 gtactggcgt gttgtcttgt acccatcatt atagaggaaa cgttcctgtc ctgtttctgt
    62521 aaaagctagc cttacctgtg ggaggtagtg tttctgactc gtcacttcta cactttcaga
    62581 tgaaaagttt tgcaggtaat ctgtaaacaa tccttggtag tagacagact gctctcgcaa
    62641 gctctcaggc aagatcagcc caaactctcc ctcagacaag ttttgcatct tgtccataaa
    62701 ctctgaagaa acggtaatct tttcttctat cagatagcgt ggtgagacat agataacatt
    62761 ccctgacggt gtgtagtcac tgagacgatt gccatctagg tccacttctg ctccatctga
    62821 gaaattgtca acattgctca taatataaaa agagtctgta ttggctaacc gttcttcagt
    62881 aaatgtctgc cactcacgat tatccttacg cgttccttct tcatcggcaa atgcactaga
    62941 ccaaccaaag gatagacggt aacggtctga ggactggctc catttattgc tagctctctc
    63001 catttcctgc atttcacggt agtggggtag gagagctgtc gcactcgatc cgaccaccaa
    63061 tacagctaag agttgcccca ccatcatcaa tgtcatcata cgtttgagag ggagtttccc
    63121 tttcaataga tccaccagac tattttcctg taaaccaagt agatagacga cacttagtaa
    63181 ggtagaaatc cctgccaagg tcaatccata aagtagaaga gcaatgatga ccagttgcac
    63241 cgttgccata aacaaggcac cttgatacca gagaatcccc aatcccaaaa gactggatac
    63301 cagcactgag cagataagct gtctcacatc ttctaacact ggtctgagag caactccaaa
    63361 caagctctca ccagctatta agcgaatccc tgcctgacga agggatttga tccgataaat
    63421 cagggtcaga ctcataaagg tcagcagaaa aatagctaaa ctcagtagca ccataggggt
    63481 ggccgtcaat agtaagacta tcgaaaatgg atcttctcca ttcgaaacaa agccttgata
    63541 accaagctct ttcaaggtgg tctgtaagct cactccatcc aaacttcctg acacaatcaa
    63601 gtaagaccct aataaatcac tcgtttctgc actctccttg gaggaaatgg tcagaccttc
    63661 tggaagcttt ccctcaccat aagtggcata ggtaaagcgt gtttctccag cttcatttgg
    63721 ctcaacgatt cgacgagcaa tgagactatt gtgctctacc gccaagtgac tcaaagcctc
    63781 tgtcacctct tcccgactag ctactggttg atttatcatc attcctgtca catcaacaga
    63841 aggatagtta ccaaataaaa tctcttctcg atggtcaacg gaagttatct ccatataaag
    63901 cgataccaat accattgaaa tcaaaataaa taaacgtttc atcatttcct ccaaaaagtt
    63961 acttggtcac ttagtgagaa ggtgaccaag taaagctaaa caatagggct ataccattct
    64021 aaacattata gtagaatgca actttctctc cccaagaagt acgaatccat gcacgagaag
    64081 tccctccagc accagcatat cccttgtcag atgaaccagt ttttctgcta acaactgttg
    64141 aactatggta ttttgaaggg tgatagtagt ttgagtaagc accaccgtta cctgaaccat
    64201 aagtccaaac accaccttct gggtattgaa cggctgcaga ggcaactgat acacctccac
    64261 ctaatgttgc tgcaatgctc gctacaagag ctaacttttt aactgtttgt ttcatattga
    64321 tactcctcta tttttgatta caagattgtt gagttacttg ctcctctttc cattatcaac
    64381 gttgatacta ttatattacc aaatgatatt ctaaaattat ttgtttttct ctaaattgtc
    64441 aaaatagcac cctgaaatga acttttatag tcattatact ccatctttat cacactatca
    64501 aggacatcaa tgtccttaaa atctaactat ttcatattat ttttagctta tatctaaaaa
    64561 aaacagttct aaagacgaac tttagaactg ttttgatacg aggacaagga catttttgtc
    64621 actgattcac tatgtttata aatatttttt gacatcctct tgccattcct ctgtcaattt
    64681 ctttactaga aatccatctc caattagctt cgcaaatgtt ttagaagact gataaaatga
    64741 ttcagctaaa ctaaaatctc tttctactct taatgcttgc ttccacaaaa acataaatac
    64801 aagaggtttc ttttgataat cttgagtttt atccataatt tcttgtaaac acgatagata
    64861 atcattaaaa caatcagtta ctcctacctt ttcaagacaa cacattcctg aaataagagt
    64921 atctctaatt ataaagtaat tctctatttg agttaccttc ttctgttcca aaagaaagag
    64981 cattagcttt tcgatttgat ttataaattt ggcaagatct tttctaatga gcatttgata
    65041 aaaaaacaaa cgaatcaaca acatatcatt tattgaataa gcttcttttt ctataatctg
    65101 aggcatatgt tcctcaagta ttaactctgc atattcaggc cttctagttc tagaagtatc
    65161 caaacacgcc tgcaatactt cacatgctaa ttgttcttct ttaggaagat tatcaaagta
    65221 tgttttataa atctcttcca aacacgcttc cttcttatcg tactcctctt ctttaccata
    65281 gattggttca cgtaaaatct ggtatttcaa ttctaaataa gcagaaggaa gagctgaaaa
    65341 atccggcata aggctataaa ctggaactcc tagccggcga gcaatatagt ctaacttggg
    65401 caaactcggt tgcgaagctc cactttcaat tcgcgacagt tgacgaactg tcagttcttg
    65461 ctcatctcca caaaaatctg gacgactaat tcctttttct atccgaatct ctttaatttt
    65521 ttgaccaatt aacatcagac gcctcctctt ctacctgctt cgaaaaatac tgtgaaactt
    65581 aaaaaattgt aacggtcaca tctttcctac tcataagatt tcatagcttc ttccacttct
    65641 accaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt gcttgccgtt agaatagccg
    65701 attcggagag tctctccgag atattctcta cgcttacagc tgtctgcccc tgctagaaaa
    65761 ccaaggcgaa tcaagtcgct acgactaatg tcaaactgac tctcatgttc aaattgttct
    65821 gtcacctgag ctagagccgt tttcaggtct tcatagctgg catgctcaat tcccagagaa
    65881 cgccccttgg tcttggactt gggaacagct tcatctcgct tgagaaaggc atgctgaact
    65941 gttggaatga ccgtcatgat catgcgccga atccgttccc cattaaaatc tgggtctgta
    66001 aagacaatga ctccatgacg ttggtgtaga cgctgaatcc gctctatgtc ctggtcattg
    66061 atggcagaac ctcgagtctc ataggtctcc acatcgaaat aacgcttgag attgaccgta
    66121 tcatcacgac cttcaaccac gatgacttgg gaaattttct ctttcattac ttgctgtcca
    66181 atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc tagctcttct gtcgtcatac
    66241 cacgcaagtc agcgataaag tcgaccacat agcgaatata ggctgtttta ttttcacgac
    66301 cacgcttggg tacaggtgct aagtaaggcg catctgtttc caccaacatc ttgtccaaag
    66361 gtaactcttt agctgcttct tggaggtcag ttgccttctt gaaagtcacc actcctgaga
    66421 aggaaatggt cataccaaga tccacaaact tctctgccca ctcaagcgtc cctgaaaatg
    66481 aatgcatgat accaccacga ggaccaacgc cctcactctt gataatctca taggtatctt
    66541 ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa gtccttagat agctgaatct
    66601 gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt catccaatgg tagtctaagc
    66661 caatttcacc taaagccaca accttggaat gttttaactt atccaacaag taagcctcaa
    66721 cttcctctgt ataagtacca gcttctgtag gatgccaacc aatagtcgca tagagctgct
    66781 catactcatc taccaactcc aaggcatgct caatcgtcgg tttatcaaaa ccaacaatat
    66841 tcatctgtgt cacacccatc tcatcagcca aggcaatttc ttctgcctca cgacctgcaa
    66901 attcttctac attcaagtgt gtatgtgtat caaaaatcat ctcttctaac ctcgttttct
    66961 atcttctatt ataccaaaaa agaggagggg cacctaattt ttcggtttcc cctcctctct
    67021 tcaatagaga gctattctgc tatcttttct atccgatatt gcccatctcc tgtcccacag
    67081 ttagagacag aagagattgg ctacattgat agaatattcc tattcagcta aagtatgtga
    67141 ttatcttggg ttctcacttt tctcacccat cactaggatt gataacttct caaaatcccc
    67201 cttataatct aactttaagt agagaataga attttctagc tgttctattt tctacgtcta
    67261 gtctttcttc ctagcaaagc aaaaccactt gttgccgccg ctagaccaag actagcaagt
    67321 gctgcacttg atgctgaacc tgtgttaggt aattgtttgc cagcaggtga ctggtaggta
    67381 acatcttgca ttgttcctgc agttgcttgc ggtgtacttg ttgtcttagg agcagcatta
    67441 ggagccactg gtctcttagg aactgtaacc atgacaatgg cttgcactcc aatcgtttct
    67501 gcttccttca catcttccat agttttcgca ttttcaatct ctttgagagc tgcttgtttt
    67561 tctgcttcca ctcttgctaa aagttctgct ttttctttat cagaaagcgg tgcgcctttg
    67621 atttcatcct gcttgtcctt ggctgctttt tcaatggcat ttttagctga ttctttttca
    67681 gtagctaatt gcttagaagc ttgtgattga gctgagtttt gtgaacctgt gtgagctgat
    67741 ccacccgcct ggctaccacc gcctgcattc gcattagcat ctgagcttcc agtattgcct
    67801 cccttatctc cacctggtgt attttctagc ttatactctg gtgtagcttc ttgagttaca
    67861 gattcacctt tcgcagattg ttgaactgta tcttttccta gaatcgtcac tactgaacca
    67921 tctgggaatg tgattgttgc tgtaccatct ccagctacat tgattgtcgc tccgtctaat
    67981 gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt cttcatctgt taaatgagtt
    68041 atatctttta catctactct ttgagcaggt gctttaacag ttgatttttc agcagtcggt
    68101 ttagtgctat cttgtgcttt tggatcttgt gctaccaatt gatttcctgg aattgtaata
    68161 gctgaaccat ctttaaagac gattgtcgct gtgccatctc cagctacttc aactttatag
    68221 taaaatgaaa taataacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
    68281 tttagaaata gaggtgtact attctagttt caatctacta taacatcgct tccgaatcca
    68341 tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt agactcgagt tcctactgat
    68401 ttttgataga attcgtttgg attatgcagc caaaactttg cgtcctttac gacgacgagc
    68461 tgccaatacg cgacgaccat ttttagttga catacggtta cggaatccgt gtttgcgcgc
    68521 acgacgaagt ttacttggtt gataagtacg tttcacgatg aatacctcct catagatttt
    68581 gtattcgttt agccggctat aaagtgatca gttactaaac atactttact attctatctg
    68641 attctttcac ttttgtcaat agctctaggc aaatgtttcc agctttttcg aatgcaagcc
    68701 ctatctacga tactgtttca agaaacgagt catcttttct tggatttggg ctaactcatc
    68761 aacacgagga aggtaaacga tacggaagtg gtctggttcc tgccagttaa agcctcgacc
    68821 atgaaccaag agaacctttt cctgcttcaa gaaatcaagg acaaactgct catcatcatc
    68881 gatacggtac atattgcggt cgatttttgg gaagatatag agccccgcct tgggtttaac
    68941 ggcagacaaa cctggaatat cttgaatggc attatagatg aaatttcttt gctcgtagat
    69001 tcgtccacca ggaagaagca attcatcgac tgattggtga ccccccaagg aagtttgtac
    69061 gacttgttgg gccaaaacgt tagagcaaag gcgcatattg gacagcatat tgagcccttc
    69121 gatatagccc ttaacatgag tcttagggcc agacaagacc atccaaccca cacggaaacc
    69181 tgctatgcgg tgggattttg acagaccatt catgctgaca cagaagacat ctggtgccaa
    69241 gctcgccaca ggcgtatgca catgtccgtc cattaccatg cggtcataga tttcatccgc
    69301 aaagataatc aaatcatttt gacgggcaat ctcaataatc tccagcaaga gttccttagg
    69361 ataaagggct ccagttgggt tatttggatt gataaggaca attgccttgg tattggaagt
    69421 gatttttgac ttgatatcgt caatatctgg gtaccattcc acagcttcat cacagatata
    69481 gtgaacggca tttcctccag ctaggctgac agccgccgtc catagaggat agtctggcat
    69541 tggcactaag acctcatccc cattgtccaa aagcccctgc atggacatga caatcaactc
    69601 actgacacca tttccaaggt aaatatcatc aatatctacg tttgggaatt tcttcagctg
    69661 gcaatactgc atgatggcct tacgggctga gaaaatccct ttggagtcag aatagccttc
    69721 actatcacgc gcattcataa tcaagtcatg aatgacctcg tctggcgctg taaagccaaa
    69781 ttctgctgga tttcctgtat tcagacgtaa aatcttttct ccattcgctc gcatccgcat
    69841 ggcttcttcc aatacaggac cacggatatc ataagcaaca tgctctaact tactagactt
    69901 gttatattct ttcatcttgt ttcctcaatt catcaggata gtaacattat accactagaa
    69961 agagaatgcg acaagtttac tgaaatgtgt tactagtttc gtatagaaga aaaaccttgc
    70021 taaaggcgag gttaagaacg tagagatagc aggtattttg caaagacaca tcacatacca
    70081 aaagataaac ctagaaaaag caagcctaga aaggagtcat aaagaagatt aaacatgagg
    70141 aaaagccccc atatcatcaa gtaatcccaa cgcccacttc gttttgcaac tagaaataag
    70201 attagatggt agagtacatg aaagactaaa aatccaataa aacttggata aagaagcggt
    70261 accagactct ctaattgcca gatcatgatc acttctacca agactgaaac taggataatt
    70321 ccataataaa ggaaatttga tttttgaaaa gagtttttca tcattctccc ttccttcact
    70381 tctttcctgc tatcctttct tttattttat catatattta tatagatttt aagccctaat
    70441 attcttttga aaaatacttt ttttgcttta cttctatagt gaaaaggttt acaattatag
    70501 taagaaaatt tcaggaggtt tcattatggc acaacgttac caaaatatca tggtcgcaat
    70561 cgatggttct aaggaagcgg acttggcttt tgtcaaggga gttcattctg ctctacgaaa
    70621 cgacgctaaa ctcaccatcg cacatgtcat tgacacacgc gctctccaaa gcgtatccac
    70681 ctttgatgct gaagtttacg aagaactcca agtcgacgct gaaagtctga tgaaagagta
    70741 cgaaaaacgt gctaaagatg ctggggtagc agatgttcat atcgtcattg aaatgggaaa
    70801 tccaaagacc ctgctagcac gtactattcc agatgccgag gaagtggacc tcatcctcgt
    70861 tggcgcaact ggtctcaacg cctttgaacg cctcttggtc ggctcttcat ctgaatacat
    70921 actccgccat gctaaggtcg atttgctggt tgtaagagaa caagaaaaaa ccttataatc
    70981 acaaagaaaa ggagccccta gctccttttt gtttacgatt tatttctctc tttatggcgt
    71041 tcgtaagcct tgagctggcg ctgcagttcc tttttaatag caggttctgg agcatatttt
    71101 tcttcccaat tatctggttt taagatttta tgggtcactg gatcaaaatg agccttacca
    71161 tctggaaaaa ttttccccat attggcctga tggacaatat caaaaatacg ttctgggtcc
    71221 acccccatca agacaaaact gccgtaggtg aagtaaagca tgtcaatcaa ggcatccact
    71281 tgccctatca aatcttgctg agcaggtgtc ttcttggcta ctttatctgc tgccttatca
    71341 agggcctgat gaagttgcga tacagcttga ccaaaatctt cttcagaagg actggctgct
    71401 cgaacaaact ccaccaattc ttctatttta aaaccagccc tatgggttgc accctctaaa
    71461 tcccaagctc gaggttcttc ttgggttcgt tcatccatca tgtggtggaa ggtcttgacc
    71521 ttattgaaat gatagtcacg gctgacaaag actttttctg aagacaaaac accaaaatgt
    71581 tccaaggcct tgtggatccc atcttgttga ttgctagtgg taatgtgctt ggcagcttcc
    71641 ttgacactgc tactaccatt tcccatagcg accgacatac caacgccagc cagcatttca
    71701 aggtcattat ctgagtcacc aaaagccatg acttggttga ggtcaaagcc atattctttc
    71761 ccaactcggc gaatgccttc taatttagaa tttccctgat tgatgacatc cgatgcaaaa
    71821 ggattgctac gtgtcaattt caagtcttca aaatcagctg ccgccttctc agattcttct
    71881 ggtgtcatca gcatcaaaac ttggtaaata ggttgattca tcaggtgaag caggtcctct
    71941 tccttttggg gaacaacctt gctgaccatg cgattaaaag actgactcac cgtccgagtt
    72001 aaaacagagg gaacgaagcg actaattcgt tgggaaaaag aacccagacc aaaggacatg
    72061 attttagaac ccaacatggc atccttggtc cctaaggcaa tctccgtgcc ctctttttta
    72121 gcatagctaa ttagatggcg caaatgtaac ttggaaatag ggctcgtgaa caagactctg
    72181 tctttactaa agatatactg gccattatag gttaccgcaa aatccagatc caaatcgtcc
    72241 atcaattcct taacaaaaaa aggtcctcgc cctgtcgcta cgccaactag taccccttgt
    72301 tctttgacaa tcttaatcgc atccttagtg gatttcaaaa cactcttgcg attgttgacc
    72361 aaggttccat cgatatcaaa aaaaacagct ttgacttcca tcctatccca atctcccctt
    72421 ttgtgataca atgattatac cacatttcag aaagagtgag taaatcatgc ctaagaaaat
    72481 ccttgtttta catacgggtg gaactatttc catgcaggcc gatgcttctg gcgctgttgt
    72541 gacgagttca gataatccca tgaaccatgt gtccaaccca cttgaaggaa tccaagtcca
    72601 cgccttggac ttttttaacc ttccaagtcc ccatatcaaa cccaaacata tgctggtcct
    72661 ctaccagaaa attaaagagg aagcagataa ctacgatgga gtggtgatca cacacggaac
    72721 cgatacttta gaggaaacag cctatttcct tgataccatg gaagttcccc atatgcctat
    72781 cgttctaaca ggagccatgc gtagctccaa tgaactcggt agtgatggtg tttataatta
    72841 cctaagtgct ttacgagtgg ccagcgatga cagggctgct gacaaaggag ttttggtcgt
    72901 tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa acacatacga ctaatgtcag
    72961 caccttccag actccaacac atggccccct tggtctcatc atgaaacagg aaatcctcta
    73021 cttcaaaaca gctgaacctc gtgttcactt tgaccttgat cacatacaag gtttagtccc
    73081 tatcatctcg gcttatgctg gtatgacaga tgagctgatt gatatgctgg atttagaaca
    73141 cttggacggt ttgattatcc aagccttcgg agctggtaat attcccaaag aaacggctca
    73201 aaaattagaa agccttctgc aaaaaggaat tccagtcgct ctggtatcac gatgctttaa
    73261 cggtattgcc gagcctgttt atgcctacca gggtgggggc gtacagttgc aaaaagcagg
    73321 cgttttcttt gttaaagaac tcaacgccca aaaagctcgc ttgaaactcc tcatcgccct
    73381 caatgccgga ctaacaggac aggctttgaa agactatatg gaaggctaat actcttcgaa
    73441 aatctctgca aaccacgtca cgtcgcctta ccgtatgtat ggttactgac ttcgtcagtt
    73501 tcatctacaa cctcaaaaca gtgtgttgcg cagcctttaa ccagccgcct agtccgctct
    73561 atggtattca ttaagtcaac atctcttgtt taagagcaca aaatcaggaa atcttctcga
    73621 ttccctgatt ttttctattt acgttttcgt gttgagctac gttctgtcaa accatgaggt
    73681 aagagaactt cacgttcttc caactcttcc ttatgcataa tcttggtcaa catacgcata
    73741 ctaatggcac caaggtcata aagaggttgg gcaatcgttg tcaagtttgg acgggtaaag
    73801 cgtgagattt gtgaatcatc actagtaata atttcaaaat cttctggcac agaaacaccc
    73861 ttatcagcca aaccgttcaa gactcctgct gccaactcat cacctgtcac aactgctgca
    73921 gttgcatttg atgaaatcaa acgctctgct aaggcgtaac catcatcata gctatattta
    73981 gattcaaata ccaaaccctc actataagtg attcctgctt ttttcaaggt ttccttgtag
    74041 ccaactaaac gaaccttacc attgatgtca tccactagcg gaccgctaac gaaagcaata
    74101 cgctcatttt ctttagcaag gtaactcact gcatcaattg ttgcttgctt atagtcaata
    74161 ttgacacttg gcaactggtg ctcaacatcg acagttcctg cgagaacaat cggagtacgt
    74221 gaacgcgaaa attctgagcg aattttatct gtcaagtgat accccatata gataatgcca
    74281 tctacctgct ttgaaaagag ggtattgaca acagaaactt ctttctcgtt atcttcatcg
    74341 ctattagcta ggacaatatt gtacttgtac atttctgcaa tatcatcaat ccccttagcc
    74401 aaactcgaaa aataaccatt ggtaatattt ggaatcacga caccgacagt ggttgtcttt
    74461 ttacttgcaa gaccacgcgc aactgcattt ggacgataat ccaaacgatc aattacctct
    74521 agcacttttt tacgggtatt ctcttttaca tttttattgc cattgaccac acggctgacc
    74581 gtcgccatgg aaacacctgc ttcacgagcg acatcataaa tggttactgt atcatctgca
    74641 ttcattcctt ttcctgtcct ttctatctca cacattcttt tacaagtaga ggtactgatt
    74701 gaagctctat atctacttac aaaagtgaag atgtgaaaat ttcgttttca tatttctact
    74761 tattccattc tatcactaat tgtaaacact ttcaagtgtt ttttgaagat tgattgaaaa
    74821 aatttcatag aaaacctagg tttagctcct tgctaccacc ttagactaaa caaaaaggag
    74881 gaaactaagc cctcctaaag ttatagtaaa atgaaataag aacaggataa atcgatcagg
    74941 acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat
    75001 ctactatagg tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat
    75061 attatatcat cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc
    75121 agcatccagt tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta
    75181 aagctgatct gcgatttctt ggttggataa gccccgggcg attcccttta agacagcaat
    75241 ctcttgttct gtcaacggat tgggacgggt catcaccatt tccatcaatt caggcgaata
    75301 ctccttgcgt ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttcgttc
    75361 ctttaataca taagcatcca ctccagcctt gaccgcacgt tcaaaatacc cagcacgctt
    75421 gaaggtcgtc accacaacca cctttgtttc aagcttttct gatcgtatcc actccaagac
    75481 ttcaagacct gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt
    75541 ttctaatagt tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg
    75601 ttgaagcgtg agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa
    75661 tactttcatc ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt
    75721 tctgactgat tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga
    75781 gctcatctcc ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt
    75841 ccttctctgt ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat
    75901 tggtcaccaa ctcaagcaaa atcatagaag ccattgactc caattcttga gtaaggctag
    75961 cagtatctag ttggttatcc gtttccacct caattccagc aatttctaac atctttttca
    76021 cagtctctag ttcggatgtc aaagttctag acttaagatt ttccacgata gttcgaactt
    76081 cattcatgga atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat
    76141 aagcctccat ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg
    76201 tatgccccag actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca
    76261 atagatttat ctgggcattt tgcttagcct gtgcttcttt caaatcctcc acaattcgaa
    76321 tccgaaccaa gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagaata
    76381 gaaactcaac ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa
    76441 gaagaaaagt ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga
    76501 gattggatag gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa
    76561 ctacataagt cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta
    76621 aaacacccaa atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc
    76681 acccagtcac tacagttagg atggggaaaa ccataaaaat taaactgatc caaaacatat
    76741 aatgtatgct tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat
    76801 ggtcaaacca aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat
    76861 gccaccctca tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt
    76921 acctactact tgcatccagt ctggaaataa agagataggc atccagagtc cacctaaaac
    76981 agccaaccct agataaagaa gattgcccac gacagacatc aactgactag ttggtaagag
    77041 agtcaaggtc aaaccaagcg ctacgaaggc aatacttcct actatcagca aaagtgcagc
    77101 cccaatccaa tttccaagag acatgtccac acctcttaca aaatgcccaa ctgagaaaac
    77161 caccaagatt gaaaccaaat aatcaaccag catacttgtt atctttgata gataatattc
    77221 taccatattt acagggctat gacgcaatgt tttctgccag ttgttgatct tgtcggtatg
    77281 taaaacaact gggaatgaga agatagctgt tgacatcatg gaaaatgcag tcatggagat
    77341 aagataatca cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa
    77401 aaataaatag aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt
    77461 ggtcaataaa aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct
    77521 tctgcgtctc ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca
    77581 tcctacatcc tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt
    77641 gtaaagaatc ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct
    77701 tgtaagctat aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg
    77761 tcgtatctcg aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca
    77821 cttcctcaat ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga
    77881 caatttccca aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa
    77941 aaacaatctt tggtcgccca attaaggtca agatgaaaga aaagagacgc ttttgaccgc
    78001 ctgataattt ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa
    78061 tttcctgatt gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa
    78121 cttttaattt ctgaacgatt atattttctt gagggaggta agccctagta tagtctaact
    78181 tagaactcgt cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc
    78241 caagcaaaca atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac
    78301 attcaccatc gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct
    78361 tactcaattt ttcaacttta accacagtca tgagactctc ctttcaacca ctccattccc
    78421 atagggaaaa cgacgaaaat cataaatcca aaccccaaag caccacaaat gaattggcga
    78481 agcaaggctt gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg
    78541 ccgataaaga aatagatgat ccctctcttc attcctcaaa ctcctttttc acatctctga
    78601 ctaatttcaa accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc
    78661 aaggaaaatg gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg
    78721 ctactactaa actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat
    78781 actacaatta tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg
    78841 acaaatgtca taaaaattct gttcaaaaca agcaagatac actatacaat aaaacacaat
    78901 cagaaaaatc taaggcaact tcctcaaaag agatatcaaa cccaattcac accataatgt
    78961 aaactaatac ttatttaaaa tcaaaaagag tagaaatttt tatcagacaa acacat
//
LOCUS       DAVLHB010000006        63129 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLHB010000006 DAVLHB010000000
VERSION     DAVLHB010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63129
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.006"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(267..782)
                     /locus_tag="VXE36_000424"
     CDS             complement(267..782)
                     /locus_tag="VXE36_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0778786.1"
                     /translation="MNRLKELRQEKKLSQKELAENIGVHYRTLQNWENGESQIKPEKA
                     QQLADYFGVSVGYLLGYSEYRELEKALDKTIFSNYPDVETFLTQEIKELIGERTKDFY
                     EYIDKQFYESYKNTTVPPEIVVKHREDFYSSFLFLPARLQKFIALWSILTETEQENIG
                     KTIELLAMRGR"
     gene            988..1188
                     /locus_tag="VXE36_000425"
     CDS             988..1188
                     /locus_tag="VXE36_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0778787.1"
                     /translation="MSKLRGYRVMLGLTQQQMADKLKISLQSYNNKELGKTPFNDKER
                     LAIKSMVAEIKSDITIDELFYS"
     gene            1203..1779
                     /locus_tag="VXE36_000426"
                     /pseudo
     CDS             1203..1779
                     /locus_tag="VXE36_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424669.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            2213..2665
                     /locus_tag="VXE36_000427"
     CDS             2213..2665
                     /locus_tag="VXE36_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778788.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            2662..2862
                     /locus_tag="VXE36_000428"
     CDS             2662..2862
                     /locus_tag="VXE36_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778789.1"
                     /translation="MTLDLDNMTQAEFDEVMAEIKAKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKSYQARA"
     gene            2864..3079
                     /locus_tag="VXE36_000429"
     CDS             2864..3079
                     /locus_tag="VXE36_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778790.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSTQFERENQRTI
                     ETPSEDLNPDYGRYIQLAGVNVWGGTE"
     gene            3076..3417
                     /locus_tag="VXE36_000430"
     CDS             3076..3417
                     /locus_tag="VXE36_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0778791.1"
                     /translation="MSLSDNDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRYGVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTILLNADLESY
                     KETLKEVGGYV"
     gene            3410..3685
                     /locus_tag="VXE36_000431"
     CDS             3410..3685
                     /locus_tag="VXE36_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0778792.1"
                     /translation="MFSLSRESEQDLAQGILEVVERYLEARDRLKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYRISDIWKFMGVENG"
     gene            3826..4692
                     /locus_tag="VXE36_000432"
     CDS             3826..4692
                     /locus_tag="VXE36_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV0778793.1"
                     /translation="MTIYETRGFQGNLVYPFDKIEPFQYIERFKPLVVPEGANIEEFK
                     RTQAPYCISGKVTPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKDVSSTLFGY
                     SYILYPTIKHNLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDLASYQKIVEHGLDYPVPQTTAEPVKQNATSLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            4736..6211
                     /locus_tag="VXE36_000433"
     CDS             4736..6211
                     /locus_tag="VXE36_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV0778794.1"
                     /translation="MEVREQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVT
                     EKVAMPQTFTVAKILSEIVTFTFISKTNIPDYSLLYIYDLDEGIYTASNDLFNLLCKT
                     FDVRIKPREWPQIKLMVRTLVKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITS
                     KISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAI
                     FYGDGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYL
                     KNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVP
                     FNADFNGEKEKPWIKNEFLANDEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDN
                     DYLLSWVKHEYMEKGWHELDVVPVFILTRSLKHYAEDMGIPKPNVYGAGKETIRHLQQ
                     LTPNHYKLKRARVKVEDYDKLDPLEFERTKLSKTNHAVVKD"
     gene            6574..7104
                     /locus_tag="VXE36_000434"
     CDS             6574..7104
                     /locus_tag="VXE36_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778795.1"
                     /translation="MTLKTFSDKAKTFTFTYEFKDLDTAMVAGHALLGYMTGTYEVPS
                     ISITHKDKGTLVAEYVEDHKLNKTFKRICDSFKDYYNQLVDDEAFEERYKRERVLQLK
                     ESEDFESLLEKVTDYELELLDYADRLLSDKPIPMDSMTAFGTLEMLGDESISLIQKLD
                     VEGEYKGLAVYTEHLK"
     gene            8251..8670
                     /locus_tag="VXE36_000435"
     CDS             8251..8670
                     /locus_tag="VXE36_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0778796.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELEALEGGIIQKPTLSHSR
                     VQTSRENKTENNFISVLKLKEDTLQRIERITEERMEISGLIDKLANPLERSVLRLFYL
                     NDLDIWGVAEEIGKSKASIYRAKKAAIEHLACMVNGN"
     gene            9418..9627
                     /locus_tag="VXE36_000436"
     CDS             9418..9627
                     /locus_tag="VXE36_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778797.1"
                     /translation="MAKVKEKWNPTISHIVPKGTKLSDGTILDKETTLTQEEFTKNPP
                     VIPAGHPYYNLLARISREEIEKEDL"
     gene            10179..13010
                     /gene="uvrA"
                     /locus_tag="VXE36_000437"
     CDS             10179..13010
                     /gene="uvrA"
                     /locus_tag="VXE36_000437"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0778798.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKNVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVTNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            13003..14064
                     /locus_tag="VXE36_000438"
     CDS             13003..14064
                     /locus_tag="VXE36_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0778799.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDVLDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            14196..14594
                     /gene="spx"
                     /locus_tag="VXE36_000439"
     CDS             14196..14594
                     /gene="spx"
                     /locus_tag="VXE36_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0778800.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            14660..15229
                     /locus_tag="VXE36_000440"
     CDS             14660..15229
                     /locus_tag="VXE36_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0778801.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGSATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            15316..15582
                     /locus_tag="VXE36_000441"
     CDS             15316..15582
                     /locus_tag="VXE36_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0778802.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            15586..16005
                     /gene="ruvX"
                     /locus_tag="VXE36_000442"
     CDS             15586..16005
                     /gene="ruvX"
                     /locus_tag="VXE36_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0778803.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            16021..16326
                     /locus_tag="VXE36_000443"
     CDS             16021..16326
                     /locus_tag="VXE36_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0778804.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            16738..17988
                     /locus_tag="VXE36_000444"
     CDS             16738..17988
                     /locus_tag="VXE36_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0778805.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            17985..18527
                     /locus_tag="VXE36_000445"
     CDS             17985..18527
                     /locus_tag="VXE36_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0778806.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            18673..20205
                     /gene="cls"
                     /locus_tag="VXE36_000446"
     CDS             18673..20205
                     /gene="cls"
                     /locus_tag="VXE36_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0778807.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            20283..20426
                     /locus_tag="VXE36_000447"
     CDS             20283..20426
                     /locus_tag="VXE36_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778808.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            20463..22001
                     /locus_tag="VXE36_000448"
     CDS             20463..22001
                     /locus_tag="VXE36_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0778809.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQTKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDTIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            22121..24328
                     /gene="nrdD"
                     /locus_tag="VXE36_000449"
     CDS             22121..24328
                     /gene="nrdD"
                     /locus_tag="VXE36_000449"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0778810.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            24340..24480
                     /locus_tag="VXE36_000450"
     CDS             24340..24480
                     /locus_tag="VXE36_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778811.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            24524..25030
                     /locus_tag="VXE36_000451"
     CDS             24524..25030
                     /locus_tag="VXE36_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778812.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            25023..25613
                     /gene="nrdG"
                     /locus_tag="VXE36_000452"
     CDS             25023..25613
                     /gene="nrdG"
                     /locus_tag="VXE36_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0778813.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGILYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            25610..26227
                     /locus_tag="VXE36_000453"
     CDS             25610..26227
                     /locus_tag="VXE36_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0778814.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGVKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            26494..26802
                     /gene="rpsJ"
                     /locus_tag="VXE36_000454"
     CDS             26494..26802
                     /gene="rpsJ"
                     /locus_tag="VXE36_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0778815.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            27019..27645
                     /gene="rplC"
                     /locus_tag="VXE36_000455"
     CDS             27019..27645
                     /gene="rplC"
                     /locus_tag="VXE36_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0778816.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            27670..28293
                     /gene="rplD"
                     /locus_tag="VXE36_000456"
     CDS             27670..28293
                     /gene="rplD"
                     /locus_tag="VXE36_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0778817.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            28293..28589
                     /locus_tag="VXE36_000457"
     CDS             28293..28589
                     /locus_tag="VXE36_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0778818.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            28607..29440
                     /gene="rplB"
                     /locus_tag="VXE36_000458"
     CDS             28607..29440
                     /gene="rplB"
                     /locus_tag="VXE36_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0778819.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            29544..29825
                     /gene="rpsS"
                     /locus_tag="VXE36_000459"
     CDS             29544..29825
                     /gene="rpsS"
                     /locus_tag="VXE36_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0778820.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            29837..30181
                     /gene="rplV"
                     /locus_tag="VXE36_000460"
     CDS             29837..30181
                     /gene="rplV"
                     /locus_tag="VXE36_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0778821.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            30194..30847
                     /gene="rpsC"
                     /locus_tag="VXE36_000461"
     CDS             30194..30847
                     /gene="rpsC"
                     /locus_tag="VXE36_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0778822.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            30851..31264
                     /gene="rplP"
                     /locus_tag="VXE36_000462"
     CDS             30851..31264
                     /gene="rplP"
                     /locus_tag="VXE36_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0778823.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            31274..31480
                     /locus_tag="VXE36_000463"
     CDS             31274..31480
                     /locus_tag="VXE36_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0778824.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            31505..31765
                     /gene="rpsQ"
                     /locus_tag="VXE36_000464"
     CDS             31505..31765
                     /gene="rpsQ"
                     /locus_tag="VXE36_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0778825.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            31791..32159
                     /gene="rplN"
                     /locus_tag="VXE36_000465"
     CDS             31791..32159
                     /gene="rplN"
                     /locus_tag="VXE36_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0778826.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            32237..32542
                     /gene="rplX"
                     /locus_tag="VXE36_000466"
     CDS             32237..32542
                     /gene="rplX"
                     /locus_tag="VXE36_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0778827.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            32566..33108
                     /gene="rplE"
                     /locus_tag="VXE36_000467"
     CDS             32566..33108
                     /gene="rplE"
                     /locus_tag="VXE36_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0778828.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            33126..33395
                     /gene="rpsN"
                     /locus_tag="VXE36_000468"
     CDS             33126..33395
                     /gene="rpsN"
                     /locus_tag="VXE36_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0778829.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            33680..34078
                     /gene="rpsH"
                     /locus_tag="VXE36_000469"
     CDS             33680..34078
                     /gene="rpsH"
                     /locus_tag="VXE36_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0778830.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            34270..34806
                     /gene="rplF"
                     /locus_tag="VXE36_000470"
     CDS             34270..34806
                     /gene="rplF"
                     /locus_tag="VXE36_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0778831.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            34890..35246
                     /gene="rplR"
                     /locus_tag="VXE36_000471"
     CDS             34890..35246
                     /gene="rplR"
                     /locus_tag="VXE36_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0778832.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            35264..35758
                     /gene="rpsE"
                     /locus_tag="VXE36_000472"
     CDS             35264..35758
                     /gene="rpsE"
                     /locus_tag="VXE36_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0778833.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            35730..35954
                     /gene="rpmD"
                     /locus_tag="VXE36_000473"
     CDS             35730..35954
                     /gene="rpmD"
                     /locus_tag="VXE36_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0778834.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            36099..36539
                     /gene="rplO"
                     /locus_tag="VXE36_000474"
     CDS             36099..36539
                     /gene="rplO"
                     /locus_tag="VXE36_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0778835.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            36552..37862
                     /gene="secY"
                     /locus_tag="VXE36_000475"
     CDS             36552..37862
                     /gene="secY"
                     /locus_tag="VXE36_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0778836.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            38013..38651
                     /locus_tag="VXE36_000476"
     CDS             38013..38651
                     /locus_tag="VXE36_000476"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0778837.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            38768..38986
                     /gene="infA"
                     /locus_tag="VXE36_000477"
     CDS             38768..38986
                     /gene="infA"
                     /locus_tag="VXE36_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0778838.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            39011..39127
                     /gene="rpmJ"
                     /locus_tag="VXE36_000478"
     CDS             39011..39127
                     /gene="rpmJ"
                     /locus_tag="VXE36_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0778839.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            39145..39510
                     /gene="rpsM"
                     /locus_tag="VXE36_000479"
     CDS             39145..39510
                     /gene="rpsM"
                     /locus_tag="VXE36_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0778840.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            39528..39911
                     /gene="rpsK"
                     /locus_tag="VXE36_000480"
     CDS             39528..39911
                     /gene="rpsK"
                     /locus_tag="VXE36_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0778841.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            39954..40889
                     /locus_tag="VXE36_000481"
     CDS             39954..40889
                     /locus_tag="VXE36_000481"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0778842.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            40901..41287
                     /gene="rplQ"
                     /locus_tag="VXE36_000482"
     CDS             40901..41287
                     /gene="rplQ"
                     /locus_tag="VXE36_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0778843.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            41552..41818
                     /locus_tag="VXE36_000483"
     CDS             41552..41818
                     /locus_tag="VXE36_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0778844.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            41828..43165
                     /locus_tag="VXE36_000484"
     CDS             41828..43165
                     /locus_tag="VXE36_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0778845.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            43432..44124
                     /locus_tag="VXE36_000485"
     CDS             43432..44124
                     /locus_tag="VXE36_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0778846.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(44227..45872)
                     /locus_tag="VXE36_000486"
                     /pseudo
     CDS             complement(44227..45872)
                     /locus_tag="VXE36_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(45862..46953)
                     /locus_tag="VXE36_000487"
                     /pseudo
     CDS             complement(45862..46953)
                     /locus_tag="VXE36_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(46966..48087)
                     /locus_tag="VXE36_000488"
                     /pseudo
     CDS             complement(46966..48087)
                     /locus_tag="VXE36_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(48304..48501)
                     /locus_tag="VXE36_000489"
     CDS             complement(48304..48501)
                     /locus_tag="VXE36_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0778847.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(48576..49352)
                     /locus_tag="VXE36_000490"
     CDS             complement(48576..49352)
                     /locus_tag="VXE36_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0778848.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            49474..50220
                     /locus_tag="VXE36_000491"
     CDS             49474..50220
                     /locus_tag="VXE36_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0778849.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            50233..51213
                     /locus_tag="VXE36_000492"
     CDS             50233..51213
                     /locus_tag="VXE36_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0778850.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            51408..51728
                     /locus_tag="VXE36_000493"
     CDS             51408..51728
                     /locus_tag="VXE36_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0778851.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            51774..52082
                     /locus_tag="VXE36_000494"
     CDS             51774..52082
                     /locus_tag="VXE36_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0778852.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            52099..53397
                     /locus_tag="VXE36_000495"
     CDS             52099..53397
                     /locus_tag="VXE36_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0778853.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            53548..55986
                     /locus_tag="VXE36_000496"
     CDS             53548..55986
                     /locus_tag="VXE36_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0778854.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            56005..56673
                     /locus_tag="VXE36_000497"
     CDS             56005..56673
                     /locus_tag="VXE36_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0778855.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SSSI"
     gene            56691..57779
                     /locus_tag="VXE36_000498"
     CDS             56691..57779
                     /locus_tag="VXE36_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0778856.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            58234..60735
                     /locus_tag="VXE36_000499"
     CDS             58234..60735
                     /locus_tag="VXE36_000499"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0778857.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            60874..61716
                     /locus_tag="VXE36_000500"
     CDS             60874..61716
                     /locus_tag="VXE36_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778858.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLTLTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            61772..62467
                     /locus_tag="VXE36_000501"
     CDS             61772..62467
                     /locus_tag="VXE36_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778859.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            62479..62895
                     /locus_tag="VXE36_000502"
     CDS             62479..62895
                     /locus_tag="VXE36_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778860.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
BASE COUNT        20007 a        11187 c        13741 g        18194 t
ORIGIN      
        1 tcgttttgtt tgaaagataa aaattaaaaa agttaatgag ttatatcttt ttattaaatg
       61 ttggttttta ttggataagg gctaactaat gcttacatat ttaatctaat aacgaatcaa
      121 gagtgaaccc tgagaaaaca cgcgcttcat gattgttgaa cgttgtggcg cgtggtatgc
      181 tataggtcgc attttcggca ctttcggcta ccctaaaaga aaaatattag tgctaaggtt
      241 tgctattggc gaatatgggg ggatttttat ctccctctca tagctaataa ttcaatagtt
      301 ttacctatat tttcttgttc agtttctgtt agtatgctcc ataaagctat aaatttttgt
      361 aatctagcag ggagaaatag aaacgagcta taaaagtctt cacggtgctt tacaactatt
      421 tcgggaggta cggtagtatt tttatagctt tcataaaatt gtttatcaat atactcataa
      481 aaatcttttg ttctttctcc gattagctct tttatctctt gagtgaggaa tgtttcaaca
      541 tcaggatagt ttgaaaaaat tgttttatcc aatgcttttt ctaattctct atactcacta
      601 taccccaaca gatatccaac gcttactccg aagtagtcag ctagttgttg ggctttttct
      661 ggtttgattt ggctttctcc gttttcccaa ttttgaagag tacgataatg aaccccaata
      721 ttttcagcta actctttttg agatagcttt ttttcttgtc ttaattcttt caatctattc
      781 atgttttatc acacctttca cagatgatta tatactatat cttagaaaaa gtacattttt
      841 tttgtgcaaa aattaaaaaa atagttgaca atagaaaaaa tattgtgtat catacaattc
      901 aagcacagaa aaaatgtgca aactcctccg acctttcacg ctttcaatct attcatggag
      961 ggggattttt tagaaagggg gaaagctatg agtaaactac gaggctatcg agttatgtta
     1021 ggactaactc agcaacaaat ggcggacaag ctaaaaattt ctttgcagtc atacaacaac
     1081 aaagaattag gtaaaacgcc attcaatgac aaagaacgcc tagcgattaa gtcaatggtt
     1141 gcagaaatca aatcagatat aaccatagat gaactatttt atagctagaa aggagcaaac
     1201 cgatggaact agtctatatg gacggtaaaa aagagcctta tacgctgagc agtattgtgg
     1261 cagaatgcac gggattgcaa catcacacaa taaccaagac gatccgcaaa catcaagtaa
     1321 ggtttgaaca gttcggaaag gttgaattta aaatccaagc tatggaaagt ggccagaata
     1381 ccaaggacta tattttgaac gaacaacaag cgaccttgtt agttacattc ttaaagaaca
     1441 ccgagcaagt ggccaacttc aaaaccaacc tggtcaaagc tttctttgaa atgcgtgagg
     1501 aactttctaa gtttcgtatg cagagggcgc tagaaaagcc aaaaagaaaa acactgcatg
     1561 aacaacctgc tgctaaaagc agtaactgac atgaacgcta agcagttaag ggaagaacgt
     1621 gggggctata acggtattga tagcttgacc agtgacgagc tggagcaata tcaggcattt
     1681 gaggatatgg taatagccat gattggcttg aatatgagtt atcaggaaat caaagctatg
     1741 gcattcagaa ataaaaaaac acgccaaaga agcgcgtgag agcaacaaaa aaggcttacc
     1801 gagaccaatc agcagagcct ttcacactaa cactaaaacg aatttaacaa agcaggcaag
     1861 ctattatcaa agaggtttta gtaaagattt atacctagat tatagcatat ttagggcaat
     1921 ttgaccatac ggagagcgcc aactctttaa actggtactt tctcacgctt tcaatttggc
     1981 gactctgagc gtgaggatta gcgttataag aaacaactca aaaaagcccc acgctcaaag
     2041 attggaccca gagagcgtga ggctgtaggc aagaaaaact gtataagaaa caaccattca
     2101 aaatccccac actcaaattt tggtcgagga gagtgtgagg atatccagta tagtaaaagg
     2161 cattaaaaag cccttagggc aattacacaa catagaaaca aaggtgaaaa acatgacaga
     2221 aacaacatac gagaatttaa ctagacatat agacagaatt agcgcagaaa tgcgagaaat
     2281 tggcgaaaaa aatgggctta gtagactttc attattggca aatcagacaa aattcatcaa
     2341 agaaaattta caccgtttac tttggattga acttcctgaa ttgaatgaca gtcataaaat
     2401 cgaggcagtt tctaaaagca ctacgggaat gtttttccac gctggtattt ttgaaatgga
     2461 cgctatgcga caagcattct ttaaacgcca agctatgcac ttttttgaca acgaagcaga
     2521 gcaacaggcg tatatagaac atgctgaaaa ggagtattta gaggctacta taaccttaaa
     2581 agatattctt tttaactcta aaaatggaac tcagagagta aataaaagtt gtcttataga
     2641 gaagtttgag gaggcaatgc aatgacacta gacctagaca acatgacaca agcagaattt
     2701 gatgaagtaa tggctgaaat caaggcgaaa cgcccaaacc tcttccagtt tattgcggat
     2761 tttgtagatc ggaaagtaag cactgaggag gtagacgaat acctgaagat gaaacatgaa
     2821 aaacaagtgg aatttatcaa gagttatcaa gcgagggcat aacatgaatg agttagattt
     2881 gaccaataca caatcggtaa tctttatggt ggtattgatt ggcttactgc tttatttaaa
     2941 ccaccgagac cgcaaaaaaa gcacccaatt tgagcgagaa aaccaacgga cgatagaaac
     3001 acctagcgag gatttaaacc ctgattatgg gcgttatatc cagcttgcag gggtcaacgt
     3061 atggggagga actgaatgag tctatcagat aatgacaaac gagtattgag actaatcaag
     3121 gtaggtgctg agaactccat aacaggggca gaaatcagcc tgatcactaa gctggcagaa
     3181 agaaccgtgc aagatattat cagccgtcta atcacgcgct atggcgttcc aatcgttggg
     3241 gttcgacacg gaacatttag aggatatttt atcccagcta acaaagagga gttactggac
     3301 ggagcaaagg cattctataa ccaagtacag gaagaacaga aacgcctaac tatcctttta
     3361 aatgctgatt tagagagtta caaagaaacc ttgaaggagg tgggcggata tgtttagcct
     3421 aagccgagaa agcgagcaag acctagcgca aggcattctg gaggtagtgg aaagatacct
     3481 ggaagcgcgt gatagactca agccacggct gacaggttta atctcagccc aggaagtcat
     3541 ggatgagtta gatattaagt atatgacgct ccaaaaatgg gaaaaagcag ggctaaggcg
     3601 ataccagccc ccactagaag atactaggaa aatctattat agaatttcgg acatctggaa
     3661 gtttatgggg gtggagaatg gctagatata acacacaccc agcacaaggc ggaggtcatt
     3721 atcatgacat taaattgtat aagcaccgtg gcagatcttt ggaacagttc caagaacaaa
     3781 agctactgaa gaagttaaaa aagaaacgca aaaaggggcg atagtatgac aatttacgag
     3841 actagaggct ttcagggtaa tcttgtctat ccatttgata agattgagcc gttccagtac
     3901 attgaacgct ttaagccttt ggtagtccct gaaggggcaa acattgaaga atttaaacgt
     3961 acacaagcgc cttactgtat cagtgggaaa gtgacaccag aaaagaatgg cagttacaag
     4021 cgaaacaact ccagtctaat ctatcgggat ttgattttcc ttgattatga cgatatacag
     4081 gggacgtctg agggctttat aaaggacgtt tctagcacct tgtttggcta ctcatatatt
     4141 ttatacccga ctattaaaca taacttagaa aagccccgtt ttcgccttgt agtgaagcct
     4201 gacaacgtga tgaatgaggc aacctataag caggtagtga aagagattgc tgacaagatt
     4261 ggactaccct ttgatatggc cagccttaca tggtcacaac ttcaagggct accagtaaca
     4321 acaggcgacc tagcaagtta tcaaaagatt gtggagcatg gacttgatta tccagtacca
     4381 cagacaacgg ctgaaccagt caaacagaat gctacaagtc ttccatacac tccaaggcca
     4441 agcggtcaga aatctatgac catgaggatc attgacacgc ttttcaacgg ctttggagac
     4501 gagggagggc gcaacgtagc attgacacgc tttgtaggct tactctttaa taagtgggtt
     4561 gattgtgacc tagagaccgc ctatgaactt acaaagatag ccaatagcgt gacggttgaa
     4621 ccattgccta ttgaagagct agaccgcact tttagcagta tagcacgggc tgaatataga
     4681 aagagaggtt agaaccatag aactagaaga attagcaaac ctaaaaagtg aaatcatgga
     4741 ggtcagagag caagaacacc ctcctagaac gatgaaggag cttgaaaatc gtatctttaa
     4801 agctggtgaa gaatggcggg cagaacatac cgaaactaaa gtaaatgaga ccacagggga
     4861 cgtcaccgaa aaggtggcca tgccccaaac attcacagta gctaaaatac tgagcgagat
     4921 tgtcacattt acttttatca gcaagaccaa tatacctgat tatagcttgc tctatatcta
     4981 cgatttagac gagggtatct ataccgctag taatgatcta ttcaatcttt tgtgtaagac
     5041 ctttgacgtt agaattaaac ccagagagtg gccacagatt aagttaatgg ttagaacatt
     5101 ggtaaagata cgaaaacctt tagaaagtgc taacctcatt cccgtacaga acggcattat
     5161 caacttagaa actaaggaac tactcccctt tagtcctaag tatgtaatta caagtaagat
     5221 aagcacggcc taccacgcgc ctaaacgagt cccaacagat agagagggca aaacttttga
     5281 tgattggcta aactcaatcg cttgtaatga tagtgaactg gtaacactgt tttggcagat
     5341 tatccttgaa gctattaacc ctaaccatac ccgaaataag tttgctatct tctacgggga
     5401 cggtaacaac ggtaagggaa catttcagcg cttccttatc aacctgatag gggaaagcaa
     5461 tatatcagcc ttaaaacctg cacagtttgc tgaaaagcat aacttagaaa ccctggtagg
     5521 taaagtttgt aatatcggag atgaagcccc aaacgaatac ttaaaaaatc cgtctgattt
     5581 aatgagtatt actagtggcg acactgttct agtcaacccc aaaggtcgcc cagcctttga
     5641 agctactttc aagttgttca atatcttttc agggaattat atccccaatg gtggcaacaa
     5701 gacaaaaggc tggtatcgta gaattatgat cgtccctttt aatgctgact ttaacgggga
     5761 gaaggaaaaa ccttggataa aaaatgaatt tttggccaat gatgaagtat tagagtatgc
     5821 actttacaaa gctatcaatc aagagccatt tactcacttt atcgaaccta aagcagttaa
     5881 aggactccta gaagaatacc aggaggataa tgactactta ctttcatggg ttaagcatga
     5941 atacatggaa aaaggttggc atgagctgga cgtagtacct gtttttatac taactaggtc
     6001 gctgaaacat tatgctgaag atatgggaat acccaagccc aatgtttatg gggcaggaaa
     6061 agaaacgata agacacttac aacagttaac acccaatcat tacaaactta aaagagcgag
     6121 ggtcaaagtt gaagattatg acaaactaga tccgctagag tttgaaagaa ccaaactatc
     6181 caaaactaat cacgctgtcg ttaaagacta aaatgttacc ttctttttat gccctaaacc
     6241 cttggtatat ctagattttt acccaaaaat gttaccttct tgttaccttg tttagaaaga
     6301 aggtaacgtt gttaaaccct tgatactact gacttttttg ggaaaatgtt accttgttac
     6361 cttgttttta actctctata tagggaaaaa tagtattttt atatataagg gctatgactt
     6421 caaaagaagg taacatggta acaaaagggt ctaaaccctt gggggtgtaa ggcttaacta
     6481 tgttacctag aaggtaacaa aatcactaaa gaaggtaaca aattaacgaa tattacataa
     6541 tttaccttaa actaagaaac ggagaaaaac aacatgacat taaaaacatt ttcagataaa
     6601 gccaaaacat ttactttcac ttacgaattt aaagacctag acactgctat ggtagcagga
     6661 cacgcgctac tgggatatat gactgggact tatgaagtac catctatttc aataactcac
     6721 aaggataaag ggacgcttgt agctgagtat gtggaagatc acaaactaaa caagaccttc
     6781 aagcgtattt gtgacagttt taaagactac tacaaccaac tagtggacga tgaagcattt
     6841 gaagaacgtt ataaacggga gcgcgtgctc caactcaaag agtcagagga ctttgagagt
     6901 ttgctggaga aagtaacaga ctacgagctg gaactgttag actatgctga tcgcttgctt
     6961 tctgataagc ctatccctat ggactcaatg accgcttttg gtacgttgga aatgctgggc
     7021 gatgaaagta ttagcctaat ccaaaagttg gacgtagagg gcgaatataa aggccttgct
     7081 gtttatacag agcatttgaa gtagaaaaca ggggagcaat ccccttttag tatgtaaccc
     7141 aatcgattta ggttttttac atgataattt gtagtagtgt gcaatttaca aaacaaacaa
     7201 atactacata ttagacggtt tgaatgttaa aaaagctaga tatatcaagg gtttaagtaa
     7261 gtagagcgtt ccaaaaaagg gtgcggtaat cgttccaaaa aaagggtgag gtaagggtga
     7321 ggttacatat atataaagta caaggttagt acaaggttgt gtatttaaaa atattaaaaa
     7381 taggctaaga ttaggctaat gtcacatact tcaaaatact aaggttttag caaggtacag
     7441 ggcttttttt ctagtgatat gaccctaaga ttaccctaag gtatagctac ttttttagaa
     7501 ccatagaacg gtaaggtttt ggtaaggtat cgaagttttc caatggtgag gttttggtga
     7561 ggtaagagca aaaaatgtaa aggttttgta aaggttgcgt atttgaaagc cccaaggtta
     7621 gcacaaggta gagaggttta ccgagggtta gaaaaggtga gattttgctt aggtagtggc
     7681 agtaaatatg cctgacaaat ggcagggtta tgtgtgttga actccgagcg aacgccgaga
     7741 aagtggatat atcccctatc atttatcaag cagataagag aaataataac cctccttaac
     7801 tcccggagaa acgacaagca gataagcgga gtttttaccc ctcttatttc cgatttactc
     7861 cttgcagaat gataggcaga taaggacgac aataagcctt cttaattgct tacaaaacga
     7921 tagggagtta agacgaattt aaaagctctt tattttcgtt tttctcctta caaaatgaca
     7981 gggaaataag aactaaaata actctcctta ttttcctacc aaatgataag gagataagag
     8041 caatttaaaa gtctgttatt ttggatttgt tgcttaccaa atgataagca gatcagcaaa
     8101 ggaataactt gccttaattg cttatcaaat ggtacgtaga atggacttga acctagagcg
     8161 aagctagaga aaatgaaaaa aagccagcac acggctgact cctttatgaa ttattcccta
     8221 aaactattat atcacaaagg aggccgaggc atgacacccg agcaggtaaa agaaaaacta
     8281 gagggcgtta agtggataaa taaggagatc aaaggcttat atttggaatt ggaagccctg
     8341 gaaggtggca ttatccaaaa gccaacacta agccatagca gggtgcagac aagcagagag
     8401 aacaagacag agaacaattt tataagtgtt ctgaagctaa aagaggatac gctccagagg
     8461 attgagcgca ttactgagga aagaatggaa atatctgggc tgatcgataa gctagccaat
     8521 ccgcttgagc gctctgttct gagacttttt tacttgaatg atctcgatat ttggggagtt
     8581 gctgaggaaa taggtaaatc taaagcttcg atatatcggg caaagaaggc agctatagaa
     8641 cacttggcat gtatggtaaa tgggaattga tttaacctta ccacagagcc tagtgcgtat
     8701 agggggcact aggctttata ttcgcccctt attcgttttg ttttggactg gataactaaa
     8761 tcaccacgga taaactacaa gccctcagaa acaaatctag gggcttttgt gagataaaaa
     8821 aataaaggtg acccaccgcc tccacagcaa gctgcttcat gggcgttaga ccacctttac
     8881 cttaacttaa ttataaatca caatgcggag tttttcaaga aaggataaga gactagaaaa
     8941 ctagctactt attggaacaa caaagctagt gagctattga agaacggtaa gattttggtt
     9001 agatacagag aaacaggcct aagcctgctc taaatctaac ttaatttctt cacaaactat
     9061 taaattcaaa taagctgaga aaacataaag ggtaacaaaa aggggactta aattgaagag
     9121 ttcagtaagc aagaaactaa cacaatcaaa cgtgcttttt ttgtaaaaat gttgtatact
     9181 taagtaaata aaggaactgg tttggcaccc aatggcttat tttaggtcgg cgcctaagtc
     9241 agttcctttt tactgtttcg accaccccaa aggatatgcc tctaacatta ttgcgtcaat
     9301 tagttattta ggctataatt aaattaacga atagaggttt tccatctccc cttgaaacag
     9361 ttcattccgc ggtaggaggt gggacgcctc tatttttacc ataaaggagt atttaacatg
     9421 gcaaaagtta aagaaaaatg gaacccaaca atatcccata ttgtccctaa aggtaccaaa
     9481 ctatcagacg gtacaatatt agacaaagaa accaccttaa cacaagaaga atttactaaa
     9541 aatccccctg ttattccagc aggacaccct tattataatc ttttagctag aataagcaga
     9601 gaggaaatag aaaaggaaga tctatagtac aaagaaatag taaaatataa tagttttgcg
     9661 cgtgatgttc gcttgaaaag gacttgttaa ggtcaacaaa atcgataacc acgcgctttt
     9721 atctatctca ccttttcgat agataaaaca accaatacgc gtgatgaaca tggtataata
     9781 tattcacagc tggaggcttg cacagtctag ccgattaggg agagttagac cgagatgtca
     9841 cacactccct tttttggtat aataaaccta tcagataagc aaaaacaact aaaaaagcgt
     9901 agctgatgac tacgctagtt tcttgcctgc tgaactcgtc aaatcttagc ccttttgtgg
     9961 ggcttttttg ctcccctttt tgcgtacttt gggggagcaa gtagtaaaaa gtaatattag
    10021 tgttttttgt taaaaagcgc gtgatataag ggttaggaag ccctaaggaa acataaaata
    10081 agaagttttt tattatacta caaaatcggc cttttgggta atagaatctc actttttttg
    10141 gtataatggt aagcaataat ggactagaaa gaacaaagat gcaagataaa attgtcattc
    10201 atggggcgcg tgcccataat ttaaaaaata ttgatgtgga gattccgcga gacaagttgg
    10261 ttgtcgtgac tggcttgtca ggttcaggga agtccagtct ggcttttgat accctctatg
    10321 cggagggaca acgtcgctat gtagagagtt tgtccgccta cgctcgtcag ttcttgggaa
    10381 atatggaaaa accagatgta gatgccattg atggtctcag cccagctatt tccatcgacc
    10441 agaaaacgac tagtaaaaat cctcgctcga cggtgggaac gacgactgaa atcaatgact
    10501 atctgcgtct cctctacgca cgtgtgggga cgccttactg tatcaacgga catggagcta
    10561 tcaatgcttc ttctgtggag caaatcgttg ataaggtttt ggagttacct gaacgccagc
    10621 gcttgcagat cttggctcct gtcatccgca agaaaaaagg ccaacataag aatgttatcg
    10681 agaaggttca gaaagacgga tatgttcgtg tccgtgtgga tggggaagtc tatgatgtga
    10741 ccgaagtgcc agagttgtct aagagcaagc aacacaatat cgatgtcgtg gttgaccgta
    10801 ttgttatcaa ggagggcatt cgtagccgtc tctttgattc cattgaagct gcccttcgta
    10861 tcgcagaagg ttatgtgatt atcgacacca tggacgattc ggagttgctc ttctctgagc
    10921 attatgcctg tccagtttgt ggatttactg tcccagagtt agagcctcgt ctcttctctt
    10981 tcaatgctcc ctttggctct tgtagtgagt gtgacggctt ggggattaag ctggaggtgg
    11041 atactgattt ggtagtgcca gatgccagca aaaccttacg tgaaggagcg ctagcacctt
    11101 ggaatcctat ctcatccaac tactatccaa acatgttaga gcaggccatg aaagtctttg
    11161 gagtggctat ggataagcct tttgaggacc tgtcagaaga agataagaac ttgattctct
    11221 atgggtcaga tggtaaggaa ttccatttcc actatgagaa tgaatttggt ggcgtgcgcg
    11281 atatcgacat tccgtttgag ggagtcgtca ctaatatcaa acgtcgttac catgaaacca
    11341 atagcgatta cactcgcact cagatgcgtc tctacatgaa tgagctgacc tgcggaacct
    11401 gtcaaggcta tcgtctcaat gaccaggcct tgtctgtccg tgtgggcggc cagcaagggc
    11461 cacatattgg agaaatctca gacctgtcta tcgctgacca cttggacttg gtgagccagt
    11521 taactttgtc tgaaaatgaa gccatcattg ctcgtcccat tctcaaggaa atcaaggatc
    11581 gtttgacctt ccttaataat gtgggtctta actatctaac cctgtcacgt tcagcaggaa
    11641 ccctttcagg tggggaaagt cagcgcattc gtttggcaac ccagattggt tccaacctat
    11701 caggcgtcct ctatatccta gacgagccgt caatcggtct tcaccagagg gacaatgacc
    11761 gcctgattgc cagtctgaaa aagatgcgtg acttgggcaa tactcttatc gtggtggaac
    11821 acgacgaaga taccatgcgt gaagctgatt atctgattga cgttggtcct ggtgccggtg
    11881 tttttggtgg tgagattgtt gcagcaggta cacctaagca agtggctcgc aacagcaagt
    11941 ctatcacagg tcagtacttg tcaggcaaac gtgtcatccc agtaccagaa gagcgccgtg
    12001 tcggaaatgg tcgttttatt gaagtgatag gagcgcgtga gaacaacttg caaaatgtca
    12061 cggctcgctt tccactagga aaatttatcg cagtgacagg tgtgtcgggt tcagggaaat
    12121 cgactctaat caacagcatt ctcaaaaaag ccattgccca gaagctcaac cgtaattcag
    12181 acaaacctgg taagtttaag actattacag ggattgagca tgtcgaccgt ttgattgata
    12241 ttgaccagag ccctatcgga cggacgccga ggtctaaccc agctacctat acaggagttt
    12301 ttgacgatat acgtgacctt tttgctcaga caaatgaagc caagattcga ggctacaaga
    12361 aggggcgctt cagtttcaac gtcaagggag gtcgctgtga agcttgctca ggtgacggga
    12421 ttatcaagat tgagatgcac ttcttgccag atgtttatgt ggcttgtgaa gtttgccacg
    12481 gaacccgcta taacagtgaa accctagaag ttcactacaa ggaaaagaat atttcgcagg
    12541 tcttggatat gacggtcaac gatgcggtag aatttttcca acacattccg aaaattcaac
    12601 gcaaactcca gaccatcaag gatgtagggc taggctatgt gaccttggga cagccagcta
    12661 ccaccctttc tgggggagaa gcccaacgta tgaagttagc tagcgaactc cacaaacgct
    12721 cgacaggaaa atctttctac attctggatg agccgacgac agggcttcat acagaggaca
    12781 ttgctcgcct gctcaaggtt ttagctcgct ttgtagacga tggcaataca gtcctcgtca
    12841 tcgagcacaa tctggatgtt atcaagacgg cagaccatat cattgacttg ggacctgagg
    12901 gcggtgtcgg tggtggaacc atcatcgtaa caggaactcc agaagaagta gctgccaacg
    12961 aagccagcta tacaggacac tatttgaaag gaaagttaca tcatgaataa acgcgtacaa
    13021 gcatttctag ctaaaatgca agaaaaagaa ctagatggta tcatcatcaa caatcttaaa
    13081 aacgtctatt atttgactgg tttttggggc tcaaacggaa cagtctttat cagccgtgac
    13141 cgtcaggtct tagtgacaga ctctcgctat atcatcgcag ctaagcaaga aaccagtggt
    13201 tttgagattg tggctgatcg tgatgaattg gctgtcattg caggaattgt taaggacatg
    13261 ggcttgactc gtatcggttt tgaagatgag atttcagtgt cttattacca ccgtatgcag
    13321 gcagcttttg caggtttgga cttgcttcca caaactcagt ttgtggaagg tcttcgtatg
    13381 attaaggatg aggcagagat tgcagcgatt cgcaaggctt gttctatctc agaccaagct
    13441 ttccgcgatg tgcttgactt tatcaaacca ggaaaaactg aaattgagat tgccaacttc
    13501 cttgatttcc gcatgcgtga gttgggagca tctggcttat cttttgatac gatcctagct
    13561 agcggtatca attcttctaa accccatgcc catccaatgc acaaaccagt ggagttggga
    13621 gaagccatta ccatggactt cggctgtctc tatgaccact atgtcagtga tatgacccgg
    13681 actatctatc taggacatgt tagcgatgag caggcagaga tttacaatac ggttctaaaa
    13741 gctaaccaag ccttgattga ccaagctaag gcaggcttag gtttccgtga ctttgacaaa
    13801 atccctcgtg atattatcat tgaggcaggt tatggtgact actttactca cggcattggc
    13861 cacggtattg gtctggatat ccatgaggaa ccctacttta gccagacttc tacagaaact
    13921 attaagacag gtatggcctt gaccgatgaa ccaggtatct atatcgaagg caaatatggc
    13981 gttcgtatcg aggatgatat cctgattaca gagacaggtt gtgaattatt gaccctagct
    14041 ccaaaagagt tgatagtcat ttagttgttt gtcaagaaaa aagtacgaaa atgacgaaaa
    14101 aagtcaaaaa aaattaaaaa taggtcgcaa gtcggatgtt ttttatggta taatagacta
    14161 aactgatagt aacatgtagc gaaaggggta ggtacatgat taaaatttat acagtctcaa
    14221 gttgtactag ctgtaaaaaa gcaaaaacct ggctcaatgc ccaccagtta agttataaag
    14281 aacaaaacct tggtaaagaa ggaattacga gagaagaatt actggatatt ctaaccaaaa
    14341 cagataacgg aatagccagc atcgtttcgt ctaaaaatcg ctatgccaaa gcccttggag
    14401 tggatattga agatttgagt gtcaatgaag ttctcaatct gattatggaa acaccgagaa
    14461 ttttaaagag cccaatcctt gtagatgaaa aacgcctgca agttggctac aaggaagacg
    14521 atattcgtgc cttcctacca cgctctgtcc gtaatgtaga aaatgcagaa gcacgtttgc
    14581 gtgcagctct ataaacatca aggctgggag cacttcccag tcttattcta ttttaatttc
    14641 aaaaagaaag aagaaagaaa tgaaaaaaat agttcttgtt agtctagctt tcctttttgt
    14701 cctggttggt tgcggacaga aaaaagaaac tggatcagct acaaaaacag aaaaagatac
    14761 gcttcagtcg gcattgccag ttattgaaaa tgctgagaag aatacagttg taactaagac
    14821 tttggtcttg cccaagtcag atgatggtag ccagcagaca caaacaatta catacaagga
    14881 caagactttt ttgagcttaa cgattcaaca aaaacgtcca gtttctgatg agttgaagac
    14941 ttatatcgac caacatggag tggaagaaac tcaaaaagct cttcttgaag cggaggagaa
    15001 ggataagtct atcattgaag ctcgtaaatt ggcaggtttc aaacttgaaa caaaactatt
    15061 gagcgcaacg gaacttcaaa caacgactag ttttgatttt caagttctgg atgtcaagaa
    15121 ggcttcccag ttggaacatc tgaagaatat tggtttggaa aatcttttga aaaatgaacc
    15181 aagcaactat atttcagata gattggcaaa tggcgcgaca gaacaataga aaatccaaat
    15241 aaatagactg cctgaattgt agaaggtaag gaattatgct ataatggtac tattctaagg
    15301 aaagagggtg ttagaatggg atttactgaa gaaacagtac gttttaaatt ggacgattcc
    15361 aataaaaaag aaattagcga aactttgaca gatgtttatg cttcgttgaa cgataagggt
    15421 tacaacccaa ttaaccaaat cgtaggttac gtattgagtg gagaccctgc ctacgttcct
    15481 cgttataata atgcacgaaa tcaaatccgt aagtatgagc gtgatgaaat cgttgaggaa
    15541 ttggttcgct actacctaaa aggacaagga gtcgatctat aacctatgag aattatggga
    15601 ttggacgtcg gttcaaaaac ggtaggggtg gcgattagcg atccgcttgg ttttacagct
    15661 caagggcttg aaatcatcca gataaatgaa gaacaaggcc aatttggttt tgaccgcgtt
    15721 aaggaattgg ttgatactta caaggtggaa cgatttgtag tgggcttgcc taaaaacatg
    15781 aacaatacaa gtggaccgcg cgtagaagct agtcaagcct acggagcaaa gctagaagag
    15841 ttttttggtt taccagtaga ctatcaggat gaacgcttga caacagtggc tgctgagcgc
    15901 atgttgattg aacaagcaga tatcagtcgc aataagcgca agaaagtcat tgataagtta
    15961 gcagctcagc tgattttaca aaattattta gatagaaaat tttaatataa aggagaggct
    16021 atgtcacacg atcataacca cgaccacgaa gaacgtgaac taatcacact agtagatgag
    16081 caaggaaatg aaaccttgtt tgaaatcctt ttgacaattg atggaaaaga agaatttggt
    16141 aaaaactatg ttcttctagt accagttaac gcagaagaag acgaagacgg acaagttgaa
    16201 atccaagctt actcattcat cgaaaacgaa gatggaacag aaggcgaatt gcaaccaatc
    16261 ccagaagact cagaagacga atggaacatg attgaagaag tcttcaacag ctttatggag
    16321 gagtgataca gtctgggaga ctgtatcagc ccaactccca gaaatgggga agagttggaa
    16381 cgtccagtgg atgtttttag cccagttcct ttaaataaga gagaactggt aggttcgggg
    16441 ggacgttttt agcccagctc ctttaaataa gatagagctg gtaagtctgg gagactgtat
    16501 cagcccaact ccagaaatgg ggaagagttg gaacgtccag tgaacatttt taccccaact
    16561 cttagaaatt gagaagagtt gggacatcta gtggatgttt ttagcccata ttcacattca
    16621 tagtagctag ttattagcta accaggtaag aggtcgggac gaaaatcctg gccttgtttt
    16681 tattagtaac catactttaa tgcgataatt gattggactt ttgtcaagga gatgtgtatg
    16741 tttgaagtag aagaatggct ccatagtcgg attggtttga attttcgatc aggtttgggc
    16801 cgaatgcagc aagcggtgga tttgttagga aatcctgagc agtcttaccc tattatccac
    16861 gtaacaggga ctaatgggaa aggatctacc attgctttta tgagggaatt atttatgggg
    16921 catggcaaaa aagttgcgac ctttacctcc cctcatatcg tctctatcaa tgaccgaatc
    16981 tgcattaatg ggcaacctat agcagacgca gactttatcc gtttgactga tcaggtcaag
    17041 gagatggaga aaacgcttct gcaaactcct gcccagttgt ccttttttga attgctgacc
    17101 ttagttgctt ttctttattt tagggagcaa gaggtggatt tggttttatt agaagtggga
    17161 attggtggct tacttgacac gaccaatgtg gtaactggag agcttgctgt catcacctcc
    17221 attgggcttg accatcaaga aaccttgggt gatagtctag aagcaattgc agagcagaaa
    17281 gctggtattt tcaaggctgg taagaaggca gtgattgcga aattgcctcc agaagctagg
    17341 cttgtctgtc agaaaaaagc cgaatcttta gctgttaacc tttatcaggc aggtcaagat
    17401 tttttaatgc tgaatggtga tttttcaagc tctttactaa atctttcaca gctgaacata
    17461 ggcttagaag gagcctatca gcaggagaat gcggccttgg cgttgcaaac ttttcttctt
    17521 tttatgggag aaagaaagga agctattgat gaacaggctg taagaaaggc cttggaacag
    17581 acccattggg ctggtcgctt ggagcgtatt cgcccacaga tttacttgga tggtgctcat
    17641 aacctccctg ccttgactcg cttggttgag tttatcaaag aaaaagagca ggaaggctat
    17701 cgacctcaaa tcctctttgg atccttgaaa cgtaaggatt atcaagggat gttgggttat
    17761 ctgactgaaa atttacctca agtggaactc aaaatgaccg gctttgacta tcaagggtct
    17821 ttggacgaga cagatgtaac aggttaccat gtaattccct cttaccgaga atttatcagc
    17881 agtttcgaag aaagggcaga cgctcaagac ttgctgttcg ttacagggtc tctctatttt
    17941 atctcagaag tacggggcta cctgctggac cgtgagcaga taaattgacc cccttttttg
    18001 aacttgttat actaggggaa ttgctggtta gagaaaattt ctctaaattg gtagcagaaa
    18061 ggaaattcat catgaaatta aaaagattca cactttctct tgcttctcta gcaagtttta
    18121 gtctcttagt agcttgttca caaagagctc aacaggttca acagcctgtt gctcagcagg
    18181 tccaacagcc tgctcaacag aataccaata ctgcaaatgc aggaggtaac caaaatcaag
    18241 cggctccagt acaaaaccaa cctgttgctc aaccgaccga tattgatggg acttatactg
    18301 gtcaggatga cggagaccgt atcactttag tggtaactgg aacgactggt acatggactg
    18361 agctcgaatc tgacggggat cagaaagtca aacaggttac atttgattca gcaaatcaac
    18421 gcatgattat tggcgatgat gtcaaaattt acactgtaaa cggtaatcaa atcgtcgtag
    18481 atgatatgga tagagaccca tcggaccaaa tcgttttaac taaataagac tatgcaagta
    18541 gaaagggctg gatttttcag cctttttact tttacctaga aaataatcat aaatacttgc
    18601 cttctaccga atacctgcgt tatactagta tcaattactt gtttttagca ttcaaactat
    18661 caaggagggg atatgaaata taggaaattt caattattga tgtccaagta tggctttagt
    18721 ctttcgatta tgctacttga actttgtctt gtttttggtc tctttcttta tttaggacgc
    18781 atggctccca ttttatggat tactgtcctc attctactga gtatcatcac aatcatttcg
    18841 atagtcaacc gtaatacgac tcctgagaat aaggtaacct ggttgttagt agcctttgtg
    18901 ccagtatttg gtcccttgct ctatctgatg tttggtgaaa ggcgattgtc caaaaaagaa
    18961 atcaaacaac tgaagaagct aggctctatg catttccaag aagcaaatag ccagctacta
    19021 aaagagaaat taaaagaaag tgacaaggca gcttatggag tcatcaagtc cttattgagt
    19081 atggatacca atgctgacat ctatgatcaa actgcctcta cattttttcc taacggagaa
    19141 gctatgtgga aaaagatggt agaagatctt aaaaaggctg agaaatttat tttcttggaa
    19201 tattacatta tagaagaagg tttgatgtgg aatcgcatac tagatatact agagcaaaag
    19261 gtagctcagg gtgtagaggt taagatgctc tatgatgata tcggctgtat ggctacttta
    19321 acaggagatt atgcacatcg acttcgtcag ctgggcatcg aggcccataa attcaataaa
    19381 gttattcctc gtttgacagt ggcttataat aacagagatc atagaaaaat attgattgtt
    19441 gatggtcaga tagcctatac tggtggggtc aatctggcag atgagtacat taaccacgtc
    19501 gagagatttg gttattggaa ggatagtgga attcgcttag acggactagc agtaaaagcc
    19561 ctgacacgct tatttttgac cacttggtac attaatcgag gagaaattag tgattttgat
    19621 caatatcatt tagaaaatca ttctatcccg agtgacggtt taaccattcc atacggaagt
    19681 ggacccaagc caatttttcg agcgcaggta gggaaaaaag tttatcagag tttaatcaat
    19741 caagcaacgg aatcggtcta tattacgaca ccttatttga ttatagatta tgatttaaca
    19801 gagacaatca aaaatgcagc tatgagaggg gtcgatgttc gaattattac cccttacata
    19861 ccagataaga agttcattca gttagtcacg agaggagctt atcccgacct tctttctgct
    19921 ggggttcgga tttatgagta tagtccaggt tttattcata gtaagcagat gttggtagac
    19981 gaagattttg cggtggtggg gacaatcaat ctcgactacc ggagcttggt acaccattat
    20041 gaaaatgcag tcttactcta taaaactcct tctataaggg aaatcgcccg agattttcga
    20101 aatatatttg cagattctca ggaagtctat cctcattcta tcaaaacgag ctggtatcaa
    20161 aagcttgtaa aagaaatcgc ccagctattc gcccctatct tataagaaat ctagaactta
    20221 ggatacaaac cagacctatt tttcttgtct tttacgaata gaaagaaaga ggaggggaat
    20281 tcatgctaac taaggaagaa gtgaatgata tgattgagtt caaacagaca catttacacc
    20341 gctttcggga aattgaaacc tttgtgaaac tatgcaaaaa atcactcaaa cagccatcgc
    20401 aagctgacaa tcctaggact ttttgatata ctaagacaga taaattgaac aggagaaacg
    20461 atatgagtgt gtatggtaga gtagaagaag ttcataagga gaatcgtgaa cctctagaat
    20521 accaaatcga acaagaatcg catcatcgtg aatcaagtcg tcttcctttg gtgaaaattt
    20581 tactatggag tacgcttgta acggggataa ctctaggagt accgctatta ctcgacttaa
    20641 tgagtgcaca agaagtgcag gatttttatg caggttgggc gcttcatcag acagggaaga
    20701 tttacagcga ctattatgga agtcaaggtt tgctttatta tttgctgact tacgtgagtc
    20761 agggaggatt tttctttgcc atctttgagt ggttagcctt ggtagcagga ggatttttcc
    20821 tttttagatc agcggacacc ttgacagagc aaggagacca agctggacat ctggtgacta
    20881 ttttttacat gctagttaca ggtcttgctt ttggtggagg ctatgcgact cttttagcgc
    20941 ttcctttctt attcgcagcc tttagtttag ttgcggctta cctaagcaat ccaagccatg
    21001 ataagggatt tgtacggatt gggctagctt tggcaggcgg atttttcttt gctcccttat
    21061 catcgctcct gtttattgct gtagtgagtt taggcttgtt ggtctttaac cttgggcata
    21121 gacgctttgc gcatgggttt tatcagtttc ttgcagtggc tttaggtttt tcacttgtct
    21181 tttatccaac tgcctactat agtgctgcaa caggaagttt tggggatgcg attagtggta
    21241 ttcgttatcc tattgacagt attcgctttg attttacttc taaaatttta gagaatatgt
    21301 ttttttatgg cttgttgtcc cttggtttgg gatttgtggt ttgtatcttt ttaggtctct
    21361 ttcaaaccaa accctttaaa ctatacgtca tttcggttcc tgcaagtctt gtggtaattt
    21421 taggtttgat tttacttttc ttttcacaag agcctctgca cgcttcttat ttgatggtcg
    21481 tcttccctgt tttcctactt ttattggtaa ccaatattaa gagtcaacag agggggcgta
    21541 gtgctagaag aagccgaaga gaaacgccag ttagcctatg gagtcgtttc ttcaaaggaa
    21601 atctatatct gctagttttt gggtttgtct atcttttgtc tgttcctttt ttgatgaagt
    21661 ttgtccttta tccagtacct tatcaagaac gtaatcgtct tgctgatttg gtaaaagagg
    21721 agacaaatac ggaagatact atctatgcat gggatgatac tgcgactctt tatcgtaaga
    21781 gtgagcgctt gtcgccatcg gcgattttgt ccccgttgca ctatacagca actgaggaaa
    21841 atcgtaataa gttacttaat gacttgaaag aaaaacaacc taaggtgatt gtggtaaatg
    21901 acaaggtggt agtctggtct gaagtggaaa cactcttaaa agaaaattac caacaagtaa
    21961 agactgatta ctcagagttt aaagtctata aaattaaata accaaatcaa tatcttgtgt
    22021 atttttaaaa attttaggat ttttaacaca agatattgat ttttcttttt agagtggtat
    22081 aatacttttt agaaagaaca ttttagaaaa gagcatgcat atgattgcac tagaagaaaa
    22141 aattacaatt ttgccaactc tcttcgtcga gaaacgagat gggagacgtg ttgtatttga
    22201 tgtggacaag attgacaagg ctctccacaa ggcggctgac aaggttatgg atgtgacacc
    22261 cctggttgaa aaacgcctca atgatctgac tgagcgaatt attacagaaa ttcatagtcg
    22321 ctttccacag ggaattaaga tttacgaaat tcaaaatatc gtagaacatg aactccttga
    22381 agccaaagaa tatgcgctgg ctgaggagta tattacttat cggacacaga gggattttga
    22441 gcgctcaaaa gcgacggata tcaactttag tattcataaa cttctcaaca aagaccagac
    22501 agttgtcaat gaaaacgcta ataaagacag tgatgtcttt aacactcagc gtgatttgac
    22561 agcagggatt gttgggaaat caatcggact gcaaatgctt cctaagcacg tagccaatgc
    22621 ccaccaaaag ggggatatcc actatcacga tttggactac agtccctata cccctatgac
    22681 caactgctgt ttgattgatt ttaagggtat gttggaaaat ggttttaaga ttggaaatgc
    22741 agaggtagag agtcccaagt ctatccagac tgcgacagca cagatttctc aaatcattgc
    22801 caacgttgct tctagccagt acggtggctg ttcagctgac cgtatcgatg aaattttggc
    22861 gccttatgca gagaagaatt atcaaaaaca tctcaaagat gcagaagagt gggtattgcc
    22921 tgaaaaacag gaagattacg cttggaagaa agcgcaaaag gacatctacg atgccatgca
    22981 atctcttgag tatgaaatca atactctctt cacttcaaat ggacaaacac cttttacttc
    23041 gttaggtttt ggtctgggaa ccagtcgttt tgaacgagaa attcaaaaag ctattttaaa
    23101 cattcgcatc aagggtcttg gttcagaaca ccgtacggct atctttccta aacttatctt
    23161 tacgcttaaa agaggcctca acttagagga aggaactccc aactatgaca tcaagcagtt
    23221 ggctctagag tgtgcaacca agcggatgta tccagacgtc ttgtcttatg ataagattgt
    23281 tgatttgaca ggttctttca aggtgcctat gggctgccgt tctttccttc aagggtggaa
    23341 ggatgaaaat ggtgtagaag tcaattcagg tcgcatgaat ctgggtgttg tgacggttaa
    23401 tctgcctcgt attgctcttg agtctgaagg tgatatgaat aagttctggg aaatcttcaa
    23461 cgagcgaatg aatatcgcag aagatgctct tgtttaccgt gtcgaacgca ctaaagaggc
    23521 gacaccagcg aatgctccta ttctttatca gtacggtgct tttggccatc gtctaggtaa
    23581 agaagaaagt gttgaccagc tctttaagaa tcgtcgtgcg accgtttcgc tgggctatat
    23641 cggcttgtat gaagtagcga cagttttctt tggtaacagc tgggaaagta atccagatgc
    23701 taaggaattc acgctagaca tcattcacga tatgaaacgc cgtgtagaag agtggtcaga
    23761 ccaatatggc taccatttct ctatctactc aacaccatcc gaaagtctga cagaccgttt
    23821 ctgccgacta gatatagaca agtttggctc tattcctgat atcacagaca aggaatacta
    23881 caccaactct ttccactacg atgttcgtaa aaatccaaca ccgtttgaaa aattggactt
    23941 tgagaaagtc tatccagaag caggtgcgtc aggtggtttc atccattatt gtgagtatcc
    24001 agtccttcag caaaatccaa aggccttgga agctgtctgg gattatgctt atgaccgtgt
    24061 aggctatcta ggcaccaata ctccgattga ccgttgctac aagtgtgact ttgaagggga
    24121 ttttgaacca actgagagag ggtttgcttg tccaaactgt ggcaatagcg accctaaaac
    24181 agtagatgtg gtgaagcgaa cttgtggcta cctaggtaat cctcaagcaa gaccgatggt
    24241 caacgggcgt cacaaggaaa tcgctgcgcg tgtcaaacat atgaatggtt caacgattaa
    24301 aatagctggg catcaagtaa caaattagaa agaaatgaaa tgggaaaata tcaactagac
    24361 gataaggggc gcgcacaagt gacccgttat cacgagaaac actctaaagg tggagctggt
    24421 aagaaagaac gcttgcttag cttcagagaa caatttttaa acaagaacaa gaaaaaataa
    24481 aagtgagagc cagctctcgc ttttctcata gtgggaggta aggatggaat tacgcagacc
    24541 aagattagcg gataagaaag ctgttttaga tatgatgaca gagtttgaaa agagccaatc
    24601 agcccatgat ggaggatttt gggatacaga gaattttgtg tatgaagagt ggttggaaag
    24661 caatcaggaa caggaaatgg ggattaatct gcctgaagga tgggttcctg caattcagtt
    24721 agtggctttt tctgagaaag gtcaagcagt tggatttctt aatctccggt tgcgcctcag
    24781 taactttcta ctagaagaag gtgggcacat tggctactcc atccgtccat ctgaaagagg
    24841 caagggttat gcaaaagaga ctctccgtca gggcttgcaa gttgctaagg aaaagaacat
    24901 caagaaagct ctggtgacct gtagcgtgaa taatcctgct agcagagcag tcattctagc
    24961 aaatggtgga atatttgagg atgctcacaa tggagtcgag cgttattgga tagaggtagc
    25021 gaatgaataa tccaaaacca caagaatgga aaagcgagga acttagtcaa ggtcgtatca
    25081 ttgactacaa ggcctttaac tttgttgatg gcgaaggcgt gcgtaactct ctctatgtat
    25141 caggctgtat gtttcactgc gagggatgtt ataatgttgc gacttggtct tttaatgctg
    25201 gcattctcta tacagcagaa ttagaagagc agattatggc agaccttgcc caaccctatg
    25261 ttcaaggctt gactttgctg ggaggggagc cttttcttaa tactggcatt ctcttgcctc
    25321 tagttaaacg cattcgaaag gaattgccag acaaggacat ttggtcctgg accggctaca
    25381 cttgggaaga aatgatgttg gaaactccag ataaactgga actcttgtca ctgattgaca
    25441 ttcttgtcga tggaagatat gatcgaacta agagaaatct tatgctccag tttcgaggtt
    25501 cgtctaacca acgaattatc gatgtgcaaa aatcgctcaa aagtgggcaa gtagtgattt
    25561 gggacaagct caatgacgga aaagaaagct atgaacaggt gaagagagaa tgaagaaaaa
    25621 ggacttagta gaccaactag tctcagagat cgagacgggg aaagtcagga cactgggaat
    25681 atacggtcat ggagcttcag gtaaatcaac ctttgcacag gaattgtacc aagctttaga
    25741 ttctactaca gtaaatttgc tagagacaga tccttatatc acctcaggac gccatctggt
    25801 agtacccaag gacgcgccga atcaaaaggt gacagccagt ctgccagtgg cgcatgaact
    25861 ggagagtttg cagagagata tccttgcctt gcaggcgggt atggatgtct tgacaattga
    25921 agaaccttgg aaggctagtg aggtcttgtc tggagtcaaa ccaattttga ttgtcgaagg
    25981 gatgtctgtt ggctttctac ccaaggaact ctttgaaaaa accatctgtt tctacacgga
    26041 tgaggagacc gaattaaagc gacgccttgc tagagatacg actgtgagaa atcgtgatgc
    26101 atcctttata ttggctagcc atcagatgag acgggagcag tatctgcgat actataaaga
    26161 aactgagtct aaggcggata tcttagtgga tcaatcagaa gataaatttg atgtcaagag
    26221 gacttaactt atgtatagaa gaaatataga agaaaatccc taattttaga aagaaaaagt
    26281 aggaaaacag tttcatccca aaaaaacgaa aaaacagcaa caaatccctt gcaatcgcag
    26341 gggctttgtg ttattctatt atggtgctgt aaattacagc cttagttttg atgcaagagg
    26401 ttgcgacacg ctcggttgca ttgccacgca acaccgcgtc ggttttcttg tggagctagc
    26461 ctattatctt aaatagacga aaaggagaaa aagatggcaa acaaaaaaat ccgtatccgt
    26521 ttgaaagctt acgaacaccg tacgcttgac acagcggctg caaaaatcgt agaatcagct
    26581 actcgtacag gtgcacaagt tgcgggtcca atcccacttc caactgaacg tagcctctac
    26641 acaatcattc gtgcgactca caaatacaaa gactctcgcg aacaatttga aatgcgtaca
    26701 cacaaacgtt tgatcgatat cgttaaccca actcaaaaaa cagttgatgc cttgatgaaa
    26761 ttggatcttc caagtggtgt aaacgtagaa atcaaacttt aatctaaaat ataaaagagc
    26821 agaggctggt gtttcaatct aattgaacac gggctaaact cggtgtgaaa aagataaact
    26881 tcctagtgtc tgctagacac tgcgtcagtt tcctattttc acgttgagtt tgacgtcctt
    26941 tgtatcttag acttgagcat aaaaaacgct cgttaaaaac tttttgaata aaaaatatag
    27001 aaaaggaact attttctcat gacaaaagga atcttaggga aaaaagtggg aatgactcaa
    27061 atcttcactg aagctggcga attgatccct gtaacagtta ttgaagcaac tccaaacgtt
    27121 gttcttcaag ttaaaactgt tgaaacagac ggatacaacg ctatccaagt tggtttcgat
    27181 gacaaacgcg aagtattgag caacaaacct gctaaaggac atgtagcgaa agctaacacg
    27241 gctcctaagc gcttcattcg tgaattcaaa aacgttgaag gcttggaagt tggcgctgaa
    27301 atcacagttg aaacattcgc agctggagat gttgttgacg taacgggtac ttctaaaggt
    27361 aaaggtttcc aaggtgttat caaacgccac ggacaatcac gtggaccaat ggctcacggt
    27421 tctcgttacc accgtcgtcc aggttctatg gggcctgttg cacctaaccg cgtattcaaa
    27481 ggtaaaaacc ttgcaggacg tatgggtggc gaccgcgtaa caattcaaaa ccttgaagtt
    27541 gtacaagttg ttccagaaaa gaacgttatc cttatcaaag gtaacgtacc aggtgctaag
    27601 aaatctctta tcactatcaa atcagcagtt aaagctggta aataataaag aaaggggaaa
    27661 tcagtcacaa tggcaaacgt aacattattt gaccaaactg gtaaagaagc tggccaagtt
    27721 gttcttagcg atgcagtatt tggtatcgaa ccaaatgaat cagttgtgtt tgatgtaatc
    27781 atcagccaac gcgcaagcct tcgtcaagga acacacgctg ttaaaaaccg ctctgcagta
    27841 tcaggtggtg gacgcaaacc atggcgtcaa aaaggaactg gacgtgctcg tcaaggttct
    27901 atccgctcac cacaatggcg tggtggtggt gttgtcttcg gaccaactcc acgttcatac
    27961 ggctacaaac ttccacaaaa agttcgtcgc ctagctctta aatcagttta ctctgaaaaa
    28021 gttgctgaaa acaaattcgt agctgtagac gctctttcat ttacagctcc aaaaactgct
    28081 gaatttgcaa aagttcttgc agcattgagc atcgattcta aagttcttgt tatccttgaa
    28141 gaaggaaatg aattcgcagc tctttcagct cgtaaccttc caaacgtgaa agttgcaact
    28201 gctacaactg caagtgttct tgacatcgca aatagcgaca aacttcttgt cacacaagca
    28261 gctatctcta aaatcgagga ggttcttgca taatgaattt gtatgatgtt atcaaaaaac
    28321 ctgtcatcac tgaaagctca atggctcaac ttgaagcagg aaaatatgta tttgaagttg
    28381 acactcgtgc acacaaactt ttgatcaagc aagctgttga agctgctttc gaaggtgtta
    28441 aagttgccaa tgttaacaca atcaacgtaa aaccaaaagc taaacgtgtt ggacgttaca
    28501 ctggttttac taacaaaact aaaaaagcta tcatcacact tacagctgat tctaaagcaa
    28561 tcgagttgtt tgctgctgaa gctgaataat ctaaggagga aatatcgtgg gaattcgtgt
    28621 ttataaacca acaacaaacg gtcgccgtaa tatgacttct ttggatttcg ctgaaatcac
    28681 aacaagcact cctgaaaaat cattgcttgt tgcattgaag agcaaggctg gtcgtaacaa
    28741 caacggtcgt atcacagttc gtcaccaagg tggtggacac aaacgtttct accgtttggt
    28801 tgacttcaaa cgtaataaag acaacgttga agcagttgtt aaaacaatcg agtacgatcc
    28861 aaaccgttct gcaaacatcg ctcttgtaca ctacactgac ggtgtgaaag catacattat
    28921 cgctccaaaa ggtcttgaag ttggtcaacg tatcgtttca ggtccagaag cagatatcaa
    28981 agtcggaaac gctcttccac ttgctaacat cccagttggt actttgattc acaacatcga
    29041 gttgaaacca ggtcgtggtg gtgaattggt acgtgctgct ggtgcatctg ctcaagtatt
    29101 gggttctgaa ggtaaatacg ttcttgttcg tcttcaatca ggtgaagttc gtatgattct
    29161 tggaacttgc cgtgctacag ttggtgttgt cggaaacgaa caacatggac ttgtaaacct
    29221 tggtaaagca ggacgtagcc gttggaaagg tatccgccca acagttcgtg gttctgtaat
    29281 gaaccctaac gatcacccac acggtggtgg tgaaggtaaa gcaccagttg gtcgtaaagc
    29341 accatctact ccatggggca aacctgctct tggtcttaaa actcgtaaca agaaagcgaa
    29401 atctgacaaa cttatcgttc gtcgtcgcaa cgagaaataa tattaaacta gtcgcttaag
    29461 caactagtaa atccgccagc tcggtagtgc tccataggag tgcaagccgc tgtggtacaa
    29521 catttaaagg agaaaatata aaaatgggac gcagtcttaa aaaaggacct ttcgtcgatg
    29581 agcatttgat gaaaaaagtt gaagctcaag ctaacgacga aaagaaaaaa gttattaaaa
    29641 cttggtcacg tcgttcaacg atcttcccaa gtttcattgg ttacactatt gcagtttatg
    29701 acggacgtaa acacgtacct gtttacatcc aagaagacat ggtaggccac aaacttggtg
    29761 aatttgcacc aactcgtact tacaaaggtc acgctgcaga cgacaagaaa acacgtagaa
    29821 aataaggaga acataaatgg cagaaattac ttcagctaaa gcaatggctc gtacagtacg
    29881 tgtttcacct cgtaaatcac gtcttgtgct tgataacatc cgtggtaaaa gcgtagccga
    29941 tgcaatcgca atcttgacat tcactccaaa caaagctgct gaaatcatct tgaaagtttt
    30001 gaactcagct gtagctaacg ctgaaaacaa ctttggtttg gataaagcta acttggtagt
    30061 atctgaagca ttcgcaaacg aaggaccaac tatgaaacgt ttccgtccac gtgcgaaagg
    30121 ttcagcttca ccaatcaaca aacgtacagc tcacatcact gtagctgttg cagaaaaata
    30181 aggaggtaaa atcgtgggtc aaaaagtaca tccaattggt atgcgtgtcg gcatcatccg
    30241 tgattgggat gccaaatggt atgctgaaaa agaatacgcg gattaccttc atgaagatct
    30301 tgcaatccgt aaattcgttc aaaaagaact tgctgacgca gcagtttcaa ctattgaaat
    30361 cgaacgcgca gtaaacaaag ttaacgtttc acttcacact gctaaaccag gtatggttat
    30421 cggtaaaggt ggtgctaacg ttgatgcact ccgtgcaaaa cttaacaaat tgactggaaa
    30481 acaagtacac atcaacatca tcgaaatcaa acaacctgat ttggatgctc accttgtagg
    30541 tgaaggaatt gctcgtcaat tggagcaacg tgttgctttc cgtcgtgcac aaaaacaagc
    30601 aatccaacgt gcaatgcgtg ctggagctaa aggaatcaaa actcaagtat caggtcgttt
    30661 gaacggtgca gatatcgccc gtgctgaagg atattctgaa ggaactgttc cgcttcacac
    30721 acttcgtgca gatatcgatt acgcttggga agaagcagat actacatacg gtaaacttgg
    30781 tgttaaagta tggatctacc gtggtgaagt tcttccagct cgtaaaaaca ctaaaggagg
    30841 taaataacca atgttagtac ctaaacgtgt taaacaccgt cgtgagttcc gtggaaaaat
    30901 gcgcggtgaa gcaaaaggtg gaaaagaagt agcattcggt gaatacggtc ttcaagctac
    30961 aactagccac tggatcacta accgccaaat cgaagctgct cgtatcgcca tgactcgtta
    31021 catgaaacgt ggtggtaaag tttggattaa aatcttccca cacaaatcat acactgctaa
    31081 agctatcggt gtgcgtatgg gatctggtaa aggggcacct gaaggttggg tagcaccagt
    31141 taaacgtggt aaagtgatgt tcgaaatcgc tggtgtatct gaagagattg cacgtgaagc
    31201 gcttcgactt gctagccaca aattgccagt taaatgtaaa ttcgtaaaac gtgaagcaga
    31261 ataaggagaa ggcatgaaac ttaatgaagt aaaagaattt gttaaagaac ttcgtggtct
    31321 ttctcaagaa gaactcgcga agcgcgaaaa cgaattgaaa aaagaattgt ttgaacttcg
    31381 tttccaagct gctactggtc aattggaaca aacagctcgc ttgaaagaag ttaaaaaaca
    31441 aatcgctcgt atcaaaacag ttcaatctga agcgaaataa tagactaggg aaggagaaat
    31501 ttcaatggaa cgcaataatc gtaaagttct tgttggacgt gttgtatctg acaaaatgga
    31561 caagacaatc acagttgtag ttgaaacaaa acgtaaccac ccagtctatg gtaaacgtat
    31621 taactactct aaaaaataca aagctcatga tgaaaacaat gttgccaaag aaggcgatat
    31681 cgtacgtatc atggaaactc gcccgctttc agctacaaaa cgtttccgtc ttgtagaagt
    31741 tgttgaagaa gcggtcatca tctaatcaaa cctgaaagga gaaaactgaa atgattcaaa
    31801 cagaaactcg tttgaaagtc gcagacaaca gcggtgctcg cgaaatcttg actatcaaag
    31861 ttcttggtgg ttcaggacgt aaatttgcaa acatcggtga tgttatcgtg gcatctgtaa
    31921 aacaagctac tcctggtggt gcggttaaaa aaggtgacgt tgttaaagca gttatcgttc
    31981 gtactaaatc aggtgctcgt cgtgctgatg gttcatacat caaatttgac gaaaacgcag
    32041 cagttatcat ccgtgaagac aaaactcctc gcggaacacg tatctttggc ccagttgcac
    32101 gtgaattgcg tgaaggtggt ttcatgaaga tcgtgtcact tgctccagaa gtactttaat
    32161 ttttaggaac aaactagtcc cctagcttca agctagggtg cccttatggg cgtaagaaaa
    32221 atcaaggaga aacctaatgt ttgtaaaaaa aggcgacaaa gttcgcgtaa tcgctggtaa
    32281 agataaggga acagaagctg ttgtccttac tgcccttcca aaagtaaaca aagttatcgt
    32341 tgaaggtgtt aacattgtta agaaacacca acgtccaact aacgagcttc ctcaaggtgg
    32401 tatcatcgag aaagaagcag ctatccacgt atcaaatgtt caagttttgg acaaaaatgg
    32461 tgtagctggt cgtgttggtt acaaatttgt agacggtaaa aaagttcgct acaacaaaaa
    32521 atcaggcgaa gtgcttgatt aatcacgaag gaaaggagaa gtataatggc aaatcgttta
    32581 aaagaaaaat atcttaatga agtagttcct gctttgacag aacaattcaa ctactcatca
    32641 gtgatggctg tgcctaaagt agataagatt gttttgaaca tgggtgttgg tgaagctgta
    32701 tcaaacgcta aaagccttga aaaagctgct gaagaattgg cacttatctc aggtcaaaaa
    32761 ccacttatca ctaaagctaa aaaatcaatc gccggcttcc gtcttcgtga aggtgttgcg
    32821 atcggtgcaa aagttaccct tcgtggtgaa cgtatgtacg aattcttgga taaattggta
    32881 tcagtttcac ttccacgtgt acgtgacttc cacggtgtcc caacaaaatc atttgatgga
    32941 cgcgggaact acacacttgg tgtgaaagaa caattaatct tcccagaaat caacttcgat
    33001 gacgttgaca aaactcgtgg tcttgacatc gttatcgtaa caactgctaa cactgacgaa
    33061 gagtcacgtg cattgcttac aggccttgga atgccttttg caaaataata taggaggtaa
    33121 atctaatggc taaaaaatca atggtagcta gagaggctaa acgccaaaaa attgttgacc
    33181 gttatgctga aaaacgtgct gcattaaagg cggcagggga ctacgaaggt ttatctaaat
    33241 tacctcgcaa cgcctcaccg actcgtttac ataatcgttg tagggttacg gggcgcccac
    33301 attcagttta ccgcaaattt ggtctgagtc gtatcgcttt tcgcgaactt gcgcataaag
    33361 gtcaaattcc tggtgtaaca aaagcatctt ggtaatttaa gatatcaaga gcgtcaaaac
    33421 tccaagtaaa aataggaaac ttgacgaaga aactaaagtt tctaggaaag tttatctttt
    33481 tcacacagag tttagcccgt gttcaattgg gcttgccaat ttgaacacga gctacagctt
    33541 tggcaaaaaa gaccaatttg ctttggagca ttgcttctgc attaaattgt ctatttttgc
    33601 tcgtgctgtt acgctctttg tatcatgtat taactagcaa gtgcaacttg caaactacta
    33661 gtaagaggag aaaaacaaaa tggttatgac tgacccaatc gcagacttcc taactcgtat
    33721 tcgtaatgct aaccaagcta aacacgaagt acttgaagta cctgcatcaa acatcaaaaa
    33781 agggattgct gaaatcctta aacgcgaagg ttttgtaaaa aacgttgaaa tcattgaaga
    33841 tgacaaacaa ggcgtcatcc gtgtatttct taaatacgga ccaaatggtg agaaagttat
    33901 cactaacttg aaacgtgttt ctaaaccagg acttcgtgtc tacaaaaaac gtgaagacct
    33961 tccaaaagtt cttaacggac ttggaattgc catcctttca acttctgaag gtttgcttac
    34021 tgataaagaa gcacgccaaa agaatgttgg tggtgaggtt atcgcttacg tttggtaaaa
    34081 tcaagataca aagctcgtaa agaacaaagc aaaattagga agttggagaa gtttgtttac
    34141 aaacaagcca acttatctat tttgcacagt tcttagagcg tgttcagttc agctcttgaa
    34201 ctaaataagt atctgaaccc cgtgaaaact ggccgttctg gcctgacaat ttaacaggag
    34261 aaaataaaca tgtcacgtat tggtaataaa gttatcgtgt tgcctgctgg tgttgaactc
    34321 gctaacaatg acaacgttgt aactgtaaaa ggacctaaag gagaacttac tcgtgagttc
    34381 tcaaaagata ttgaaatccg tgtggaaggt actgaaataa ctcttcaccg tccaaacgat
    34441 tcaaaagaaa tgaaaactat ccacggaact actcgtgccc ttttgaacaa catggttgtt
    34501 ggtgtatcag aaggattcaa gaaagaactt gaaatgcgtg gggttggtta ccgtgcacag
    34561 cttcaaggat ctaaacttgt tttggctgtt ggtaaatctc atccagacga agttgaagct
    34621 ccagaaggaa ttacttttga acttccaaac ccaacaacaa tcgttgttag cggaatttca
    34681 aaagaagtag ttggtcaaac agctgcttac gtacgtagcc ttcgttcacc agaaccatat
    34741 aaaggtaaag gtatccgtta cgttggtgaa ttcgttcgcc gtaaagaagg taaaacaggt
    34801 aaataatgtt gagtggttga tcatcaacca ccaacctatt ttccaacttt gtgcatagca
    34861 cacgatttaa aactaaagag gtgaaaactg tgatttcaaa accagataaa aacaaactcc
    34921 gccaaaaacg ccaccgtcgc gttcgcggaa aactctctgg aactgctgat cgcccacgtt
    34981 tgaacgtatt ccgttctaat acaggcatct acgctcaagt gattgatgac gtagcgggtg
    35041 taacgctcgc aagtgcttca actcttgata aagaagtttc aaaaggaact aaaactgaac
    35101 aagccgttgc tgtcggtaaa ctcgttgcag aacgtgcaaa cgctaaaggt atttcagaag
    35161 tggtgttcga ccgcggtgga tatctatatc acggacgtgt gaaagctttg gctgatgcag
    35221 ctcgtgaaaa cggattgaaa ttctaatagg aggacactag aaaatggcat ttaaagacaa
    35281 tgcagttgaa ttagaagaac gcgtagttgc tgtcaaccgt gttacaaaag ttgttaaagg
    35341 tggacgtcgt cttcgtttcg cagctcttgt tgttgttggt gaccacaatg gtcgcgtagg
    35401 atttggtact ggtaaagctc aagaagttcc agaagcaatc cgtaaagcag tagatgatgc
    35461 taagaaaaac ttgatcgaag ttcctatggt tggaacaaca atcccacacg aagttctttc
    35521 agaattcggt ggagctaaag tattgttgaa acctgctgta gaaggttctg gagttgccgc
    35581 tggtggtgca gttcgtgccg ttgtggaatt ggcaggtgtg gcagatatta catctaaatc
    35641 acttggttct aacactccaa tcaacattgt tcgtgcaact gttgaaggtt tgaaacaatt
    35701 gaaacgcgct gaagaaattg ctgcccttcg tggtatttca gtttctgatt tggcataaga
    35761 aaggggataa aatggctcaa attaaaatta ctttgactaa gtctccaatc ggacgcattc
    35821 catcacaacg taaaactgtt gtagcacttg gacttggcaa attgaacagc tctgttatta
    35881 aagaagataa cgctgctatc cgtggtatga tcacagcagt atctcactta gtaacagttg
    35941 aagaagtaaa ctaatgaagt tttaggggat gtgcactgta ccatccccta aaactagata
    36001 tagtcatcta tgatgacatc gtataggcga gttgatgggg gagacaacct tttctccctt
    36061 atcggcgcta gcattttaca aaagaggaga aaataaaaat gaaacttcat gaattgaaac
    36121 ctgcagaagg ttctcgtaaa gtacgtaacc gcgttggtcg tggtacttca tcaggtaacg
    36181 gtaaaacatc tggtcgtggt caaaaaggtc aaaaagctcg tagcggtggc ggagttcgcc
    36241 ttggttttga aggtggacaa actccattgt tccgtcgtct tccaaaacgt ggattcacta
    36301 acatcaacgc taaagaatac gcaattgtga accttgacca attgaacgtc tttgaagatg
    36361 gtgctgaagt aactccagtt gttcttatcg aagcaggaat tgttaaagct gaaaagtcag
    36421 gtattaaaat tcttggtaac ggtgagttga ctaagaaatt gactgtgaaa gcagctaaat
    36481 tctctaaatc agctgaagaa gctatcactg ctaaaggtgg ttcagtagaa gtcatctaag
    36541 agaggtgacc tatgtttttt aaattattaa gagaagctct taaagtcaag caggttcgat
    36601 caaaaatttt atttacaatt tttatcgttt tggtctttcg tatcggaact agcattacag
    36661 ttcctggtgt gaatgccaat agcttgaatg ctttaagtgg attatccttc ttaaacatgt
    36721 tgagcttggt gtcggggaat gccctaaaaa acttttcgat ttttgcccta ggagttagtc
    36781 cctatatcac cgcttctatt gttgtccaac tcttgcaaat ggatatttta cccaagtttg
    36841 tagagtgggg taaacaaggg gaagtaggtc gaagaaaatt gaatcaagct actcgttata
    36901 ttgctctagt tctcgctttt gtgcaatcta tcgggattac agctggtttt aataccttgg
    36961 ctggagctca attgattaaa actgctttaa ctccacaagt ttttctgacg attggtatca
    37021 tcttaacagc tggtagtatg attgtcactt ggttgggtga gcaaattaca gataagggat
    37081 acggaaacgg tgtttccatg attatctttg ccgggattgt ttcctcaatt ccagagatga
    37141 ttcagggcat ctatgtggac tactttgtga acgtcccaag tagccgtatc acttcatcta
    37201 tcattttcgt aatcattttg attattactg tattgttgat tatttacttt acaacttatg
    37261 ttcaacaagc agaatacaaa attccaatcc aatatactaa ggttgcacaa ggtgctccat
    37321 ctagctctta ccttccgtta aaggtaaatc ctgctggagt tatccctgtt atctttgcca
    37381 gttcgattac tgcagcgcct gcggctattc ttcagttttt gagtgccaca ggtcatgatt
    37441 gggcttgggt aagggtagca caagagatgt tggcaactac ttctccaact ggtattgcca
    37501 tgtatgcttt gttgattatt ctctttacat tcttctatac gtttgtacag attaatcctg
    37561 aaaaagcagc agagagccta caaaagagtg gtgcctatat ccatggagtt cgtcctggta
    37621 aaggtacaga agaatatatg tctaaacttc ttcgtcgtct tgcaactgtt ggttccctct
    37681 tccttggtgt gatttccatt ttaccgattg cagctaaaga tgtatttggt ctttctgatg
    37741 ttgttgcctt tggtggaaca agtctcttga tcattatctc tacaggtatc gaaggaatca
    37801 agcaattgga aggttaccta ttgaaacgta agtatgttgg tttcatggac agaacagaat
    37861 aaaagtattt actgaatcag taaatactga gggagtggag gtttaaactc tgacatttgt
    37921 aagagttgga tctcccctct tctattttgt ttttaaatcg gggtgaaaaa actttttgct
    37981 tctatttaaa aacaaaataa ggagatcaaa ttatgaatct tttgattatg ggcttacctg
    38041 gtgcaggtaa gggaactcaa gcagcaaaaa tcgtagaaca attccatgtt gcacatatct
    38101 caacaggtga tatgttccgc gctgcaatgg caaatcaaac tgaaatgggt gttcttgcta
    38161 agtcatatat tgacaagggt gaattggttc ctgacgaagt tacaaatgga atcgtaaaag
    38221 aacgcctttc acaagatgat attaaagaaa caggattctt attggatggt tacccacgta
    38281 caattgaaca agctcatgcc ttggacaaaa cattggctga acttggcatt gaactagaag
    38341 gtattatcaa tattgaagtt aaccctgaca gcctcttgga acgtttgagt ggccgtatca
    38401 tccaccgcgt aactggagaa actttccaca aggtctttaa cccaccagtt gactataaag
    38461 aagaagatta ctaccaacgt gaagatgata agcctgagac agtaaaacgt cgtttggatg
    38521 ttaatattgc tcaaggagaa ccaatcattg ctcactaccg tgccaaaggt ttggttcatg
    38581 acatcgaagg taatcaagat atcaatgatg tcttctcaga tattgaaaaa gtattgacaa
    38641 atttgaaata aagcgttttt cacacttgca aaaatccgct acaaatgtta tactgaaata
    38701 gtctgactta taattgttgt ctctgtgtct agaggcatcg aatcgaaatt tatggaggtg
    38761 cttttgcgtg gcaaaagacg atgtgattga agttgaaggc aaagtagttg atacaatgcc
    38821 gaatgcaatg tttacggttg aacttgaaaa tggacatcag attttagcaa cagtttctgg
    38881 taaaattcgt aaaaactata ttcgtatttt agcgggagat cgtgttactg tcgaaatgag
    38941 tccatatgac ttgacacgtg gacgtatcac ttaccgcttt aaataatcga aaaacttgga
    39001 gggataagaa atgaaagtaa gaccatcggt caaaccaatt tgcgaatact gtaaagttat
    39061 tcgtcgtaat ggtcgtgtta tggtaatttg cccagcaaat ccaaaacaca aacaacgtca
    39121 aggataagat agaaaggaga aaacatggct cgtattgctg gagttgatat tccaaatgac
    39181 aaacgcgtag taatctcatt gacttatgtt tatggtatcg gacttgcaac atctaagaaa
    39241 attttggctg ctgctggaat ctcagaagat gttcgtgtac gtgatcttac atcagatcaa
    39301 gaagatgcta tccgtcgtga agtggatgca atcaaagttg aaggtgacct tcgtcgtgaa
    39361 gtaaacttga acatcaaacg tttgatggaa atcggttcat accgtggtat ccgtcaccgt
    39421 cgtggacttc ctgtccgtgg acaaaatact aaaaacaacg ctcgcactcg taaaggtaaa
    39481 gctgttgcga ttgctggtaa gaaaaaataa tataggaggt aaaagtcttg gctaaaccaa
    39541 cacgtaaacg tcgtgtgaaa aagaatatcg aatctggtat tgctcatatt cacgctacat
    39601 ttaataacac tattgttatg attactgatg tgcatggtaa tgcaattgct tggtcatcag
    39661 ctggtgctct tggtttcaaa ggttctcgta aatctacacc attcgctgct caaatggctt
    39721 ctgaagctgc tgctaaatct gcacaagaac acggtcttaa atcagttgaa gttactgtaa
    39781 aaggtccagg ttctggtcgt gagtcagcta ttcgtgcgct tgctgccgct ggtcttgaag
    39841 taacagcaat tcgtgatgtg actccagtgc cacacaatgg tgctcgtcct ccaaaacgtc
    39901 gccgtgtata atcatcgcat tacactgctt ttcgtttaag agggagtaac taaatgatcg
    39961 agtttgaaaa accaaatata acaaaaattg atgaaaataa agattatggc aagtttgtaa
    40021 tcgaaccact tgaacgtggc tacggtacaa ctcttggtaa ctctcttcgt cgtgtacttc
    40081 tagcttctct accaggagca gctgtgacat ctatcaacat tgatggtgtg ttacatgagt
    40141 ttgacacagt tccaggtgtt cgtgaagacg tgatgcaaat cattctgaac attaagggaa
    40201 ttgcagtgaa atcgtacgtt gaagacgaaa aaatcatcga actggatgtt gaaggtcctg
    40261 ctgaagtaac agctggtgac attttgacag atagcgatat tgaaattgta aatccagatc
    40321 attatctctt tacaatcggt gaaggttctt ctctaaaagc gactatgact gttaacagtg
    40381 gtcgtggata tgtacctgct gacgaaaata aaaaggataa tgcaccagtt ggaacacttg
    40441 ctgtagattc tatttataca ccagttacaa aagtcaacta tcaagtggaa cctgctcgtg
    40501 taggtagcaa tgatggtttc gacaaattaa cccttgaaat cttgacaaat ggaacaatta
    40561 ttccagaaga tgctttaggg ctttcagcac gtattttgac agaacatctt gatttgttta
    40621 caaatcttac tgagattgct aagtcaactg aagtgatgaa agaagctgat actgaatctg
    40681 acgaccgtat tttagatcgt acgattgagg aactggactt gtctgtgcgt tcatacaact
    40741 gtttaaaacg tgccggtatc aatactgtgc atgatttgac agaaaaatct gaagcagaga
    40801 tgatgaaagt acgaaatctt ggacgcaaga gtttggaaga agtgaaactc aaactcattg
    40861 atttgggtct tggattaaaa gataaataaa ggaggaatac atggcttacc gtaaactagg
    40921 acgcactagc tcacaacgta aagcaatgct tcgcgatttg acaactgacc ttttgatcaa
    40981 cgaatcaatc gtgacaactg aagctcgtgc taaagaaatc cgtaaaactg ttgaaaaaat
    41041 gattactcta ggtaaacgtg gtgatttgca tgcacgtcgt caagcagctg ctttcgtacg
    41101 taatgaaatc gcatctgaaa actatgatga agcaactgat aagtacactt ctactacagc
    41161 acttcaaaaa ttgttctcag aaatcgcacc tcgttatgct gaacgtaacg gtggatacac
    41221 tcgtatcctt aaaactgaac cacgtcgtgg tgatgcagcg ccaatggcga tcatcgaatt
    41281 agtataaaat catcaatttt gttgagtgtt atgatgatgg agtcttgtgc tcttagtcta
    41341 gctctggtct accgctagga tttcggtcct agcgggaaca ctcatcataa gttgggatag
    41401 tagacgcttg tttacgaaat tgtttttttc ttaagaacaa cttcgtaagc aggcgttttt
    41461 gagtattttc gttagaatta tgctatacta tttgaaaaga atcctgttta atgttaaggt
    41521 ttcttatttt aagaagaatt ggagtttact tatgaaagcc attataactg ttgttggtaa
    41581 agataaatct ggaattgttg caggtgtttc tggtaaaatt gcagaattag gattgaatat
    41641 tgacgatatc tctcaaactg tattggatga atattttacg atgatggctg ttgtatctag
    41701 tgatgaaaag caagatttta cctatcttcg taatgaattt gaagcttttg ggcaaacttt
    41761 gaatgtaaaa atcaatattc agagtgcagc gattttcgaa gctatgtata atatctagga
    41821 ggtcatcatg gatattagac aagttactga aaccatcgcc atgattgagg agcaaaactt
    41881 cgatattaga accattacca tggggatttc tcttttggac tgtatcgatc caaatatcaa
    41941 tcgtgctgcg gagaaaatct atcaaaaaat tacgacaaag gcggctaatt tagtagctgt
    42001 tggtgatgaa attgcggctg agttgggaat tcctatcgtt aataagcgtg tatcggtgac
    42061 acctatttct ctgattgggg cagcgacaga tgcgacggac tacgtggttc tggcaaaagc
    42121 gcttgataag gctgcgaaag agattggtgt ggactttatt ggtggttttt ctgccttagt
    42181 acaaaaaggt tatcaaaagg gagatgagat tctcatcaat tccattcctc gcgctttggc
    42241 tgagacggat aaggtctgct cgtcagtcaa tatcggctca accaagtctg gtattaatat
    42301 gacggctgtg gcagatatgg gacgaattat caaggaaaca gcaaatcttt cagatatggg
    42361 agtggccaag ttggttgtat tcgctaatgc tgttgaggac aatccattta tggcgggtgc
    42421 ctttcatggt gttggggaag cagatgttat catcaatgtc ggagtttctg gtcctggtgt
    42481 ggtgaaacgt gctttggaaa aagttcgtgg acagagcttt gatgtagtag ccgaaacagt
    42541 taagaaaact gcctttaaaa tcactcgtat cggtcaattg gttggtcaaa tggccagtga
    42601 gagactgggt gtggagtttg gtattgtgga cttgagtttg gcaccaaccc ctgcggttgg
    42661 agactctgta gcacgtgtcc ttgaggaaat ggggctagaa acagttggca cgcatggaac
    42721 gacggctgcc ttggccctct tgaacgacca agttaaaaag ggtggagtga tggcctgcaa
    42781 ccaagtcggt ggtttatctg gtgcctttat ccctgtttct gaggatgaag gaatgattgc
    42841 tgcagtgcaa aatggctctc ttaatttaga aaaactagaa gctatgacgg ctatctgttc
    42901 tgttggattg gatatgattg ccatcccaga agatacgcct gctgaaacca ttgcggctat
    42961 gattgcggat gaagcagcaa tcggtgttat caacatgaaa acaacagctg ttcgtatcat
    43021 tcccaaagga aaagaaggcg atatgattga gtttggtggt ctattaggaa ctgcacccgt
    43081 tatgagggtt aatggggctt cgtctgtcga cttcatctct cgcggtggac aaatcccagc
    43141 accaattcat agttttaaaa attaagaaaa taggagaaat tttaagttct atttaagatt
    43201 agatgtgtat actataatca ttaaataaag acctcctaat attatttgaa acagataaca
    43261 ctgaattagt ttgaatttga ttttcatcta atatctttat ttaatgaact cctaaacttt
    43321 ttcataataa tctcctaaac tttttcataa taatctcctt caaaagtcgc ctgtatgggt
    43381 ggcttttatt ttatcattca tgatataata gaagcaaacg gaggacggaa aatggtaaaa
    43441 gtacgattgt atttggtacg tcatggcaag accatgttta acacgattgg tcgcgcgcaa
    43501 ggttggagcg atactccctt aactgctgaa ggtgaacgag ggattcaaga gttaggaatc
    43561 ggtttgcgag aatctgatct acagtttgag cgcgcttatt cgagtgattc tggtcgtacc
    43621 attcagacca tgggaattat ccttgaagag cttggcttgc aggggaaaat cccttatcgc
    43681 atggacaagc gtatcagaga atggtgtttc ggtagttttg atggagccta tgatggcgat
    43741 cttttcatgg gcattattcc tcgtatcttt aatgtggacc acgttcacca attgtcttat
    43801 gctgaactgg ctgagggctt ggtagaggtc gatacagctg gttgggctga aggctgggaa
    43861 aaactcagtg gccgaattaa ggaaggcttt gaaatgattg caaaagaaat ggaagatcaa
    43921 ggtggaggta acgcccttgt tgtcagccat ggaatgacta ttggaaccat tgtttatctg
    43981 attaatggca tgcatccgca tggtctagat aatggtagcg tgacgattct tgaatatgag
    44041 gacggtcagt ttagggttga agttgtcggt gaccgtagtt accgagagct aggacgtgag
    44101 aagatggaag aaggctctat ttaatcagtc tagacttgct tgccatgagc tagggatttg
    44161 ataagaatat caagataaga aaaaacagcc gagggtactc ctttcggctg tttttgatgt
    44221 ggaaaactaa agtgtaatgc tattgctttt agagattttc ataaacaaga gcaaggaacc
    44281 tactgttaga acagtcagga tagttgacaa ggctgcggct acaccgtaat ttcctctgag
    44341 aacctctgta taaatagcta cagtcattgt tcttgttttg acattgtaga ggaggataga
    44401 agtagagagt tttgaaatca ttgtgaccca agataagatg gctccagaaa tgataccaga
    44461 tagcatcatt ggagttgtaa tcttagcaaa ggtattgaga cgactacttc ctaagctttc
    44521 agcagcttct tcaatacttg gtgctatttg ttgtaagcta gcaacagatg agcgaatagt
    44581 ataaggtaat cttctgacag atagagacat aatcaagatg aaagcagtcc ctgtaatcat
    44641 aagaaatcca cttccaaata gaccagtatt gaaggaagaa atgaaggcaa tccctagaac
    44701 ggttcctggt acaatataag gtaccatact gaggctgtca attaagtttg taaacaaatt
    44761 ccgttttcta acggctaggt aggagataaa tgtcgcaaat agaacaacta gaactaaggc
    44821 aatcaaaggg atacgaatgg tattgaaaat agcagctccc atacgattga aagctagctt
    44881 gtaactgttt ggagaataac ctttaaaaaa taccatacct gatgttttta ggaaagaggt
    44941 ataaattaag tagatttgag gtaaaacaga gataaagata attccgtaga ctgttgcata
    45001 aatggcagtc atttttcctt ttgtagtttt tttaggctca attggatgga gcagattcat
    45061 gctgaaactg tagcggtttg caatgtgttt ttggataagg aaaattgcca aggcaatgat
    45121 aatcgccata attgcaaaag cagaatttcc tccaacctcg ctaataaatt gggtataaat
    45181 caggacaggg aaagtccgat atccttcgcc aatcaacata ggcgttccaa agtctgagaa
    45241 tgctctcata aatacaagca aggagctgct agtaaggttg gaactaggag aggtaaaaca
    45301 accgttacga taggtttaaa tccgaaggac cccatgcttt cagctgcttc aagtagagaa
    45361 ttgtcaatac tgttcattgt tccagcaaca tatagaaata ccagtgggaa tagttgcagt
    45421 gtaaagacaa gtataattcc tttgaatcca taaatatcga tagctggaag ataaagggca
    45481 tttgtcaaaa atttagtgat gacctcattt cgtcccagca agagaatcca ggagtaggct
    45541 cctacgaaag gagctgacat ggaagcaatg ataatcaata tttgtagaaa tttcttcccc
    45601 ttgaagtcat acatagagaa gagataagct aatagggttc ctacaactaa ggaagtgaca
    45661 gtagcggtaa tggaaaccct gaaactgttg actagtgtct cagagtagta ggctttacta
    45721 aagaaagtga caaaattagc tagtgagaat tatccttcat gtataagtgc ttacttgagc
    45781 acggtaacga taggataaac gagaaagaca agataggtaa gaaagatgaa gaaagaggag
    45841 gctgtccaaa tatttagttt tttacgttcc atggttgact ccttttatca ggttttggga
    45901 accatctgca gaaaagatgt ttaatttttg cgtattgatt cgtagacgaa tacgattgcc
    45961 tttttgtagt tcttcttcaa aagttgattc ttcactaact tgaatttttg aggcaaaacc
    46021 tgtctcaatg aaatactccg tatttagtct aagatagacg ctatcgctaa tagttccttc
    46081 aatatctcca gattcatctt tgataaactc ttcgggacga atgcttacat gaatagcttg
    46141 ctcctcaacc tgatcaagag ctggcattcg aagggcatag ccatctgaaa agacgatata
    46201 agcgccgtcg ctccgttttt caagattggc agggataata tttgtgcgtc cgataaaggt
    46261 tgccacaaac tcattagctg gtttatgata gagttttttt ggtcggccga tttgttggat
    46321 caccccatct ttcataacag caatttggtc tgaaatagcc atggcttctt cttggtcgtg
    46381 ggttacataa acagttgtaa ttcccacttc gtgttggatt tctcggatgg cttgacgcgt
    46441 atccaagcga agtttggcct ccagattact aagtggctcg tccatgagga gaacacttgg
    46501 attaaccgct aaggcgcatg ccaaggtgac acgttgttgt tgtccaccac tgagtttatc
    46561 gggctttcaa tccgcatatt gagcaatttg catgagttca agatacttgt tggtctgttg
    46621 aatcaattct tcttttggaa ccttcttttg cataagacca aaagcaacgt tgtctcggac
    46681 agtcaaatgt gggaaaatag cgtagttttg gaaaaccatc ccgatattgc gtttgctggg
    46741 ttccatatta ttgatttttg tatcatcgaa gtaaaattct ccatctttga tactgttgaa
    46801 acctgcaatc atacgaagaa gggtcgtttt cccacatctt gaagctccaa gaagggtaaa
    46861 gagacttcct tttggaattg taatgttcaa attctcaata acagggacat cgtggtagat
    46921 ttttttggcg ttaataattt cgatctcact catagtgaac ctcttttact gtttagattg
    46981 gatatctgta aagacttcgt tgtatttctt aacgatatct gatttattct tgatgacata
    47041 atcataatct tcagtgagtg ttttgatttt gtcaattggt ttcatgtttt cgcttgtttt
    47101 agcattttta cgaacaggac ggttagtagt ggttgtacca agtgtatctt gtacttcttg
    47161 agagataata aaatcgataa atttcttggc attttccata tttttagctt ttttaacgat
    47221 agcagcacta gcaggtagga agacggttcc ttcttttgga tagactacct taatgttagc
    47281 tccgtcattt aagagtttaa ctgctggatc ctcataagag agaccaacag ccatttctcc
    47341 atcagcgact gctttataga caccagatga acttgaaccg attttatagt gtgttgaaaa
    47401 tagaatagta cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgatta
    47461 atttgtcctg ttcttatttc atttcactat gccatcaata agtgtgaaaa gatcttttac
    47521 ataagaccaa gccttatcat ctttgtaacc accttgagct tgtagcatat ttgttaattg
    47581 agcaaaggcg ctagaagagt ttgctgggtc agcagttgcg atttttcctt ttagttcagg
    47641 tttgagaagg tcgctatatc cttcgatgtt catgccttta gttaaatcag ggttgacgat
    47701 taaaacacta ccatctagtg tataaggagt agagaagcca gttgtgtttt gatattcttt
    47761 gataacatta tcattttctt ttgaaatata gttttcaaag agttctccgt gggtagcata
    47821 ttgtgtataa gaaccaccaa agataatatc agctacagga acttcttttt ctgactctag
    47881 ttttttgaaa agttctccag taccagcttg aatcagttct attttgatac catatttttc
    47941 ttcaaaggca ggaatagttg ctccaattaa gccctctgag tttggtgaat aaacgactag
    48001 cgaaccgccg tctcctttat cagatgaact gtcatcggca gattcattag aagaacaagc
    48061 agcataatac atccatttct ttttcatgat ggatacctcc gttgtgttat ttaagtttat
    48121 tttaaaacaa tgtaagcgtt tttaaaacct acaattctat tctatagtgt attgaatcta
    48181 taacagtaca ctttgactgc taaaatattt ctataaatta atttgacttt cctgatagag
    48241 atgttcacat cttatttcaa ttcactatat tagagtaaaa ttctctacaa aaagaagaat
    48301 agcctatttg actattcttc cgagtgattt caatttcttt ggggaaatat ggagatactt
    48361 tttaaatact ttggcaaaat atttatagtc tgaaaatcca acttggtcag agatagcgct
    48421 taaaggggag ttgggagatt cagccatctt atctatagct tgtttcaggc gatattgtaa
    48481 gatatattca tttagagtca tggggaagtc ttctttgata accttatata gatgcttgtt
    48541 atctgcaaat agctagagca tttcaaggaa ataaactaga aataacaatt aatatggtgg
    48601 ttcagaaata ccttttgata atcaataaga tcttcaggat gaagtgcgtt gattccatcc
    48661 atttcatatt tccgatttaa taaacgatat ttgttttcac caaattgatg aaaagggagt
    48721 agttgaactt ggtcgatgtt taatgagtta aatagagtag cgaatttttc tgcatcctct
    48781 aaactattgt taaaattagg aataactggg attcttaaaa cgatagtttt attttgagaa
    48841 aaagcataat gaatgttttt aataatcatt tgattaaaaa ccccagtcac ttttttatgt
    48901 tttatagaat tataatgttt taggtctgtg tagataaaat ccacatattg aattaaatcg
    48961 ataaattttt catgatcaac aaaggcagta gtttcaatgg cagtgtgtat gtgatgttct
    49021 ttagctgatt ttaagatggc tttagcaaat tcaaactgag caaatatttc acctcctgat
    49081 aaagttaaac ctccaccgga ttcttcgtaa aattctttgt cttttaatac ctctgtaata
    49141 atttcttcta cagtcttttc ttcaccgact aaggtgaatt tctctcgttg agcatctttc
    49201 attttttcag gtttcattct ttgagattca ggattagaac accatggaca gcgcagagga
    49261 catcctttta aaaaaacagt tgtacgaata cccgggccgt catgaattga aaagtgttga
    49321 atattaaaaa taattccttt agatatttcc ataagagttc ctcctcttca taagtctatc
    49381 ctatcacaaa aacgaaagaa aaacaattac gaacgaaagg ttaatttgtt gttttttgct
    49441 ttttattttg gtagaataaa acggaggtgt aaaatgaaaa gattggaaca aattattaaa
    49501 ttagtatcag aatatgaaaa gatcgacgtt aatacattat cggaaaaatt aaatgtatcg
    49561 aaagtaacga ttagaaaaga tttagataaa ttagagtcaa aaggtttatt acacagagag
    49621 catggatatg ctgtattaaa tagtggagat gacttaaatg tacgtttgtc aattaattat
    49681 gaaattaaga gaaaaattgt tcaggaagca gtaaaattgg tgtcagataa tgaaacaata
    49741 atgatagaat ctggatcgac ctgtgcttta cttgctgagg aaatttgcaa gcaaaaaaga
    49801 aatgttacga ttgtaacaaa ttcatttttt atagcaaatt ttgtgagagc ttatgattca
    49861 tgtcgtatta ttgttcttgg tggagagttt cagaaggatt cacaggttac tgtgggacct
    49921 ttattaaaag aaatgataca gacttttcat gtgcatcaag cttttgttgg gacagatggc
    49981 tacgataaag agatgggctt tacaggaaaa gatttaatgc gcagtgaggt agttcaatat
    50041 atttcagcag cgtcggataa agtcattgta ctaactgact caagtaaatt tgataaaagg
    50101 ggtacagtaa gaagatttgc tttaagtcaa gtctatgaag taataacaga cgaaaaactt
    50161 tctaaacaaa atatagctac attagaaaat gctgggataa tggttaaggt agtttcgtaa
    50221 gaggttaagt gtatgaatca agataggaat aaactgctct ctaaaattgc ttatctgtat
    50281 tatattgaaa acttaaatca gtcacaaata gcagcaaaat taggaattta tagaacctct
    50341 attagtagaa tgttaacaga agcaaggaat gcaggaattg ttaaaattga aatagagaat
    50401 tttgatacca atatgtttaa gttggaaaat tatgtaaaag aaaaatatgg tctggaaagt
    50461 ttagaaatta ttccaaatga atttgatgat aatccaacaa ttttatctga aagaatttct
    50521 caagttgcag caggtgtcct taggaatcta attgatgata atatgaaaat tggcttttct
    50581 tgggggaaaa gtttaagtaa tttagtagat ttaattcaca gtaaaagtgt ccgaaatgtt
    50641 cacttctatc ctctagcagg tggtcctagt cacatacacg ctaaatacca tgtgaataca
    50701 ctgatttatg aaatgtctag aaaatttcat ggagagtgta catttatgaa tgcaacgatt
    50761 gtgcaagaaa ataaattgtt agcagatggt attttgcaat caagatattt tgaaaatttg
    50821 aaaaatagtt ggaaagattt agatatagct gtagtcggaa ttggtgattt tagcaataaa
    50881 ggaaagcatc aatggttaga catgcttaca gaggatgact ttaaagaatt gaccaaagtt
    50941 aaaactgtag gagaaatttg ttgtcgattt tttgattcaa aaggtaaaga agtctatgaa
    51001 aacttacagg aaagaacgat agcaatctct ttggaagatt taaaaaatat tcctcaaagt
    51061 ttagctgttg cttacggtga tacgaaagta tcttcgattc tttctgtctt gcgtgctaat
    51121 ttagtaaatc atttgattac agacaaaaat acaattttaa aagttttgga agaagatggg
    51181 gatttgactt ttagagagat tctaggtgag tgaaaatgat agactgattc agtttatcgt
    51241 ttttcttttt agttgattgc acatttgtgc ttatataaac aaaaatagtt tatctgttgt
    51301 ttttggattg acaactttat tatgtagttg tattctatag ttacaaaaga aaattttaaa
    51361 atttcaaatg aaaaaagctt tttacatagt gaaatgagga ggaatttatg gaaattattg
    51421 ttccagatca aattatcatg ggtttaattt tatatgctgg cgatgcgaaa caacatattt
    51481 ataaagcatt agattacata aagaacggta catgtgaacg atgtgaagaa gaaatccagt
    51541 tagctgatgc agccttatta gaagctcata atctacaaac aaaattcttg gcacaggaag
    51601 cgtctggtac aaagacagaa attacagctc tctttgttca ttcacaagat catctcatga
    51661 ctagtatgac ggagattaat ttaatcaaag aaattattag tttgagaaaa gaacttcata
    51721 aaaaataata ctagagtatt atcattgtta ttaacataga ggaggaaaac ataatggtga
    51781 agattggttt gttttgtgca gcaggttttt ctactggtat gcttgtaaat aatatgaaaa
    51841 ttgcagcgca atctagtgga gttgaggcag aaatagaggc gttttctcag tctaaattag
    51901 cggattatgc gccaaatata gatgttgcac tattgggtcc acaagttgct tatacattag
    51961 ataaatcaaa agaaatttgt gataagtgtg atgttccgat agctgttatt ccgatgatgg
    52021 actatggtat gttagatggg aaaaaagtat tagatttggc cctatctttg attagtgggt
    52081 aagaaaagga gatttattat gtcaaagatg gatgttcaga aaatcattgc accgatgatg
    52141 aagtttgtga atatgcgtgg cattatagct ctaaaagatg ggatgttagc aattttgcca
    52201 ttgacagtag ttggcagttt gttcttgatt atgggacaat tgccgttcga aggattaaat
    52261 aagagcattg ctagtgtttt tggagctaat tggacagagc cgtttatgca agtatattca
    52321 ggaacttttg ctattatggg tctaatttct tgtttttcaa ttgcctattc ttatgctaag
    52381 aatagcggag tagaggcttt accagctgga gttctatctg tatctgcatt ctttattttg
    52441 ctaagatcat cttatatccc taaacaaggt gaggcgattg gggacgctat tagtaaagtt
    52501 tggtttggag gccaaggaat tatcggtgct atcattatag gtttggtagt aggaagtatt
    52561 tataccttct ttataaagag aaaaattgtt attaagatgc cagaacaagt tccacaagct
    52621 attgccaaac agtttgaagc aatgattcca gcatttgtaa ttttcttatc ttctatgatt
    52681 gtatatattt tagcgaagtc attgactaat ggcggaacat tcatagaaat gatttattct
    52741 gctattcaag ttccgttgca aggtttaact ggatctttgt atggtgctat tggaattgca
    52801 ttctttatat catttttgtg gtggtttggt gttcatgggc aatcggtagt aaatggagta
    52861 gtgacagctc tgcttttatc taatcttgat gctaataaag ctatgttagc ctctggtaat
    52921 ctatcattag aaaatggtgc acatattgtt actcaacaat ttttagattc atttttaatt
    52981 ctatcaggtt cagggattac gtttggtctt gtagttgcca tgctttttgc agcaaaatca
    53041 aaacaatacc aagccttagg aaaagttgca gcttttccag caatatttaa cgtaaatgag
    53101 ccagttgtat ttggatttcc gattgtcatg aatccagtta tgtttgtacc tttcattctt
    53161 gttcctgtac ttgcagctgt gatagtatat ggagctattg caacaggttt catgcaacca
    53221 ttctcagggg taacattgcc ttggagtaca ccagctattc tatcaggatt tttggtgggt
    53281 ggatggcaag gtgttgtgac tcagttatta gtattggcga tgtctacaat ggtttacttt
    53341 ccattcttta agatacaaga tcgtttagct tgccaaaatg aaatcaaaca atcttagagg
    53401 tatttgtgtg ttactgttaa actcacacat ttgtgctaaa aattagagag ttaaaatttt
    53461 tctagttaaa agcttgaaaa tttctataaa aatcggtatt atattttcga aagaaataaa
    53521 aatattttcg aaagaaaggt gcttacgatg gtaaatacag aagtagcaag aacaacaatc
    53581 aagacagaat attttggcag ccttactgaa aggatgaaca aatatcgaga agatgtttta
    53641 aataaaaaac cttatattga tgctgagaga gcagttctag caacacgcgc ctatgaacga
    53701 tacaaggaac aacctaatgt cctaaaacgt gcatatatgc tgaaagaaat tttggaaaat
    53761 atgtctatct atattgaaga agaatctatg attgcgggaa atcaagcttc ttccaataaa
    53821 gatgctccta tttttccgga atatacgcta gaatttgttc tcaatgagtt ggatcttttt
    53881 gaaaagcgtg atggagatgt tttctatatt acagaagaaa caaaagaaca acttagaagt
    53941 attgctccgt tttgggaaaa taataattta cgtgctagag ctggtgcctt attacctgaa
    54001 gaagtgtctg tttatatgga aacaggattc ttcggtatgg aaggtaagat gaattctgga
    54061 gatgctcact tagcagttaa ctatcagaaa cttttgcaat ttggtttaag aggttttgaa
    54121 gagcgggctc gtaaagcgaa ggtagctcta gatttaacag atccagcaag tattgataaa
    54181 tatcattttt acgactctat atttatcgta atcgatgcta ttaaagtata tgcaaagcgc
    54241 tttgttgctc ttgctaaaag tttagccgaa aatgcaaatc ctaaacgtaa gaaagaatta
    54301 cttgagattg cagatatttg ctctagagtc ccatatgaac cggcaactac ttttgcagaa
    54361 gctattcaat cagtttggtt tattcaatgt attttacaaa ttgaatctaa tggccactct
    54421 ctttcatatg gccgttttga tcaatatatg tatccatata tgaaggctga tttagaaagt
    54481 ggtaaagaaa cagaagatag cattgttgaa cgtctgacaa atctttggat taagacaatt
    54541 acaattaata aggttcgcag tcaatcacat acattttctt cagcaggaag tcctttatat
    54601 caaaatgtta caattggtgg acagactcga gataagaagg atgctgttaa cccattatct
    54661 tatttggtat taaaatcagt tgcacaaacc catctaccgc aacctaatct aactgtacgt
    54721 taccatgcag gtttagatgc tcgtttcatg aatgagtgta ttgaagtgat gaaacttggt
    54781 tttggtatgc ctgcatttaa taatgatgag attattattc cttcttttat tgcaaaagga
    54841 gtattggaag atgatgctta tgattacagt gccattggat gtgttgaaac ggcagttccg
    54901 gggaaatggg gctatcgttg cacaggtatg agttatatga acttccctaa ggttctactt
    54961 atcacgatga atgatggaat tgatccggct tcgggtaaac ggtttgcacc aagctttggt
    55021 cattttaagg atatgaagaa cttttctgaa ttagaaaatg cttgggataa aacactaaga
    55081 tatttgacac gaatgagtgt tattgttgaa aattctattg atttatcatt ggaacgagaa
    55141 gttcctgata ttctatgttc agcattgact gatgattgta ttggtcgtgg aaaacacctt
    55201 aaagaaggtg gagcagtata tgattatata tcaggattgc aagttggaat tgcaaatttg
    55261 tcggattcat tagctgcaat taaaaaattg gtgtttgagg aagaacgtat aagcccaagt
    55321 cagctttggc atgcactgga aacagattat gccggagaag aaggtaaggt cattcaagaa
    55381 atgttgattc atgatgcacc taagtatggt aatgatgatg attatgctga caaattggtt
    55441 actgctgctt atgacattta tgttgatgaa attgctaaat atcctaatac acgttatgga
    55501 agaggtccaa ttggaggaat tcgttattca ggaacatctt ctatctcagc caacgtaggg
    55561 cagggacgtg gaacattagc aactccagat ggacgcaacg cgggtacacc gttagcagag
    55621 ggttgttcac catcacataa tatggatcaa cacggcccta catctgtttt aaaatctgtt
    55681 tcaaaattac caacagatga aatcgtaggt ggggttctct taaatcagaa agtaaatcct
    55741 caaacgttag ccaaagaaga agataaatta aaactaattg ctttgttacg aacattcttt
    55801 aatcgtttac atgggtacca tattcaatac aatgttgttt ccagagagac gctgattgac
    55861 gctcagaaac atcctgaaaa acacagagac ttaattgttc gtgttgcagg atactctgca
    55921 ttcttcaatg ttctttctaa ggcaacccaa gatgacatta taggacgtac tgagcatact
    55981 ttgtaaaata aagaggttct ttttatggaa tttatgcttg acacattaaa tttagatgag
    56041 attaaaaagt ggtctgaaat tttgccgcta gctggggtaa cttcaaatcc cactattgca
    56101 aaaagagagg gttctattaa tttttttgaa cgaatcaaag atgtaagaga attgattggc
    56161 tctacaccct ctattcatgt tcaggtgatt tctcaagatt ttgaaggcat cttaaaggat
    56221 gctcatgaaa ttcgaagaca agcaggagat gatatattta tcaaagtacc tgttactcca
    56281 gctggattac gtgcaataaa ggtgctaaaa aaagagggct accatatcac tgcaacagct
    56341 atttatacag ttattcaggg attattagct atcgaagcag gagcggatta cctagctcca
    56401 tattataata gaatggaaaa tctgaacatt gattcaaatt ctgtcattcg tcaattagct
    56461 cttgctattg atagacagaa ctctcctagt aagattttag ctgcatcctt taaaaatgta
    56521 gcacaagtaa ataatgcttt agctgcaggt gcgcatgctg ttacagcagg agcagatgtt
    56581 tttgaatcag ctttcgccat gccatctatc caaaaggcgg ttgatgattt ttctgacgat
    56641 tggtttgtta ctcaaaatag tagttccatt tagatagaga ggaaatacat atgagaattt
    56701 ttgctagtcc ttctagatat attcaggggg aaaatgcctt gtttgaaaat gccaaatcaa
    56761 ttttggattt gggaaattac cctattctat tatgcgatca gttggtttat gatattgttg
    56821 gaaaacgatt tgaagattac ctacataggt atggtttcca tattgttctg gcgctattta
    56881 atggtgaagc ttctgacaat gaaatcaatc gagttgttgc cttggctgag aaagaaaatt
    56941 gtgatagtat tatcggtctt ggtgggggaa agacgattga tagcgcaaaa gctattgcag
    57001 atttgattga aaagcctgtt attattgctc caacaattgc atcgaccgac gcacctgtat
    57061 ctgctttatc tgttatttat acagatgaag gtgcatttga tcattatcta ttttattcta
    57121 aaaatccaga tttagttttg gttgatacaa aagttatttc acaagcccct aagcgtttat
    57181 tagcgtctgg tattgcagat ggtttagcaa cttgggttga ggcgcgtgcg gttatgcagg
    57241 caaatggaaa aactatgttg ggacaacagc aaacattggc tggagttgca attgcgaaga
    57301 aatgtgaaga aacgctgttt gcagatggtt tacaggctat ggcagcttgt gaagctaaag
    57361 tggtgacacc agcattagaa aatattgttg aagctaatac tttattgagt ggtctaggtt
    57421 ttgaaagtgg aggattagct gcggcgcatg caattcataa tggttttact gcattgacag
    57481 gtgacattca tcatttaaca catggtgaaa aagtagctta tggaacttta gtacaactat
    57541 tattggaaaa tagacctaaa gaagaacttg ataagtatat tgagttttac aaaaaaattg
    57601 gtatgccaac aactctaaaa gaaatgcatt tggatcaagt tggatatgat gatttaataa
    57661 aagttggtaa acaagcaact atggagggtg agacaattca tcagatgccg tttaagattt
    57721 cgccttcaga tgttgctcaa gctattatcg ctgtagatgc ctatgtaaat tcaaaataaa
    57781 caataaggac tactgttttc caaatggtag tcttttattg atccctgtat tgaattctat
    57841 agaagattga aataggatga gaacaaatcg attgggaaag taaaattaat ttctataaat
    57901 gttttagcaa ttgtttcgta ctatttcaga ttcagtctac tatacgttct tcataaatca
    57961 aaaagcgaca taggtagtcg gctatttatt gtgaatacat taattagcat tccagtttta
    58021 tcttcggtct aaaataagta ttttgtgcta tacgagataa gcttcttgac ttactccttg
    58081 atttactgca taacaatggg ataaaaagtg ggagatagag caattcatag tcatcaaaat
    58141 taatgagata cagtatacag tttttccttt aaacacattt caaattccct caaaaatggt
    58201 ataatagtaa catcacaaaa ttggagagag accatgagtt tttacaatca taaagaaatt
    58261 gagcctaagt ggcagggcta ctgggcagaa catcatacat ttaagacagg aacagatgca
    58321 tcaaaaccta agttttatgc gcttgatatg ttcccttatc cgtctggagc tggtctgcac
    58381 gtaggacacc cagaaggtta tactgcaacc gatatcctca gtcgttacaa acgtgcgcaa
    58441 ggctacaatg tccttcaccc aatgggttgg gatgcttttg gtttgcctgc agagcaatac
    58501 gctatggata ctggtaatga cccagcagaa tttacagcgg aaaacattgc caacttcaaa
    58561 cgtcaaatca atgcgcttgg attttcttat gactgggatc gtgaagtcaa tacaacagat
    58621 ccaaactact acaagtggac tcaatggatt ttcaccaagc tttacgaaaa aggcttggcc
    58681 tatgaagctg aagtgccagt aaactgggtt gaggaattgg gaactgccat tgccaatgaa
    58741 gaagtgcttc ctgacggaac ttctgagcgt ggaggctatc cagttgtccg caaaccaatg
    58801 cgccaatgga tgctcaaaat cacggcttac gcagagcgct tgctcaatga cttagatgaa
    58861 ctagattggt cagagtctat caaggatatg caacgcaact ggattggtaa atcaactggt
    58921 gccaatgtaa ctttcaaagt aaaaggaaca gacaaggaat ttacagtctt tactactcgt
    58981 ccggacacac ttttcggtgc gactttcact gtcttggctc ctgaacatga attagtagac
    59041 gctatcacaa gttcagagca agcagaagct gtagcagact ataaacacca agccagcctt
    59101 aagtctgact tggctcgtac agaccttgct aaagaaaaaa caggggtttg gactggtgct
    59161 tatgccatca accctgtcaa tggtaaggaa atgccaatct ggattgcaga ctatgtcctt
    59221 gctagttatg gaacaggtgc ggttatggct gtgcctgccc acgaccaacg tgactgggaa
    59281 tttgccaaac aatttgacct tccaatcgtc gaagtacttg aaggtggaaa tgtcgaagaa
    59341 gctgcctaca cagaggatgg cctgcatgtc aattcagact tcctagatgg actcaacaaa
    59401 gaagacgcta ttgccaagat tgtggcttgg ttggaagaaa aaggctgtgg tcaggagaag
    59461 gttacctacc gtctccgcga ctggctcttt agccgtcaac gttactgggg tgagccaatt
    59521 ccaatcattc attgggaaga tggaacttca acagctgttc ctgaaactga attgccgctt
    59581 gtcttgcctg taaccaagga tatccgtcct tcaggtactg gtgaaagtcc actagctaac
    59641 ttgacagatt ggcttgaagt gactcgtgaa gatggtgtca aaggtcgtcg tgaaaccaac
    59701 actatgccac aatgggctgg ttcaagctgg tactacctcc gctatattga tccacacaat
    59761 actgagaagt tggctgatga ggacctcctc aaacaatggt tgccagtaga tatctacgtg
    59821 ggtggtgcag agcatgctgt tcttcacttg ctttacgctc gtttctggca caaattcctc
    59881 tatgacctcg gtgttgttcc gactaaggaa ccattccaaa aactctttaa ccaagggatg
    59941 attttgggaa caagctaccg tgaccaccgt ggtgctcttg tggcaaccga caaggttgaa
    60001 aaacgtgatg gttccttctt ccatgtagaa acaggggaag agttggagca agcgccagcc
    60061 aagatgtcta aatcgctcaa gaacgttgtt aacccagacg atgtggtgga acaatacggt
    60121 gccgataccc ttcgtgttta tgaaatgttt atgggaccac tcgatgcttc gattgcttgg
    60181 tcagaagaag gtttggaagg aagccgtaag ttccttgacc gagtttaccg tttgattaca
    60241 agtaaagaaa tccttgcgga aaacaatggt gctcttgaca aggtttacaa cgaaacagtc
    60301 aaagctgtta ctgagcaaat tgagtctctc aaattcaaca cagctattgc ccaacttatg
    60361 gtctttgtca atgctgctaa caaggaagat aagctttatg ttgactatgc caaaggcttt
    60421 attcaattga ttgcaccatt tgcacctcac ttggcagaag aactctggca aacagtcgca
    60481 gaaacaggtg agtcaatctc ttatgtagct tggccaactt gggacgaaag caaattggtt
    60541 gaagatgaaa ttgaaattgt cgtccaaatc aaaggaaaag ttcgtgccaa actcatggtt
    60601 gctaaagatc tatcacgtga agaattacaa gaaatcgctt tagctgatga aaaagtcaaa
    60661 gcagaaattg acggtaagga aatcgtgaaa gtaattgcgg taccgaataa actcgttaat
    60721 atcgtcgtta aataacgagt ttattagctc tatctgccac cttcaatagt ccactggact
    60781 attgaagcca actaaattag ttaacattgt tgtgaaataa aaagaagtaa ctctagagta
    60841 tgaactttag agttactttt agaataggtc agaatgaata gattagtgaa cgatagcagg
    60901 aagtgtgaaa ttttattatt taagatttct attattgtag tgtcagttat agtattagta
    60961 atgtcaatag tgggtgcata ttattttaaa aattgtcttt gggacaagga aagtttaaat
    61021 ttgacactca ctttagacac tctctttgca gtttttatta ctttctttag tttttcaaat
    61081 gataaatcaa gcaatatttt tggaatatct ccaaatgaaa ttataaggac acagtctgaa
    61141 gtgtatcaat ttttatttac aaaatctttt gcaactctat taatagtgac aaatttgtta
    61201 tccattattc attattttgg agccaaaaat ttaatagttt cttttaatga aacttatcct
    61261 cgtattcaat ccagtgttgg tatcatgtgg ctaccactgt ttggtattct gataatctat
    61321 tttatttggc tcttaataga gggattaaaa tatatcagaa aaataaatta tattattcaa
    61381 aatagggaaa taatctattt ttattcgcag gtaaaagttg tagataaact tactgattct
    61441 gaatcgaaaa aatacggtga atatattgat ttgtacgaat cgtgtcgtca gaacaattta
    61501 agtgttctac ttaactttct tcaaaattcg gatgataaac gaggagttat tgctagtaac
    61561 tcagtgagaa ttatgtttga atctttggat aaagcagacc aaattgcggc cctgaatatt
    61621 tgtagaaact atgtagcacg agaaaatgtt ttaaataaag aagatgcaga aaaattgtta
    61681 aatgaaattg ataaaaaact tgaaattagc agataggaca attcaaatag agttgagtaa
    61741 aaagtttgaa aagtgaaaca aggagaaagc tatgccagta aatgaatatg gtcagatgat
    61801 tggtgagtca atggaaggtt atacacccgg tgcactgcct tctattgatt tcttagaagg
    61861 gcgttatgct aggatagagg ctctctcggt agaaaaacat gcggaggatt tgctagctgt
    61921 ttatggcccg gatactcctc gggagatgtg gacctatctt tttcaggagc cagtagcaga
    61981 tatgggggag ctggttagcc ttttaaatca gatgttggct cgtaaggacc gtttttacta
    62041 tgcaatcata gacaaggcga ctggtaaggc tttgggaact ttttctctca tgcgcattga
    62101 ccagaataac cgagtaatag aagtcggagc agtcactttt tctccagagc taaggggtac
    62161 acggatagga actgaggctc agtatctcct agctcgctat atttttgagg agctaaacta
    62221 tcgtcgctac gagtggaaat gcgatgcctt aaatctgcca tccagacgag ttgcggagcg
    62281 tttgggattt gtctatgaag gaaccttccg ccaggcggtg gtttataagg ggcgtacgag
    62341 agatacggat tggttgtcta tgattgatat ggactggcct caagtcaaag atcgtttgga
    62401 aacatggctg cgtcctgaaa attttgataa aaatggacag cagtacaaga gcttgagaga
    62461 actttaagag gtgttgagat gattactatt aaaaagcaag aaattgtcaa gctagaggat
    62521 gttttgcatc tctatcaggc tgtcggttgg acaaattata cccatcaacc agagatgctg
    62581 gagcatgcct tatcgcattc attagtaatt tatctggcac ttgatggtga tgctgtggtg
    62641 ggcttgattc gtttggttgg agatggattc tcatcagtat tggttcagga tttaatcgtt
    62701 ttaccaatct atcagcgtca aggaattggt agtgccttga tgaaagaggc tttagaggat
    62761 tacaaagatg cttatcaagt ccagctggtg acagaagaga cagaaaaaaa cgtgggattt
    62821 tatcgttcta tgggctttga aatcttatcc acctataatt gtatagggat gacttgggcg
    62881 aatcgagaaa aataacaaaa cttgtttttt cttaagcaaa atttaaggat ggtctagtat
    62941 tatataatca ttaaataaag acctcctaac tttatttaat aaaatcctaa acttttttca
    63001 tcacaatctc ctaatgaagc cacccaatca ggtggctttt ttgcgtggtg aggtgctggt
    63061 gatagaaatt ttttgcaaaa tagtaaaatt ttagaaaagt taaggtagtt ttaagtttcg
    63121 tcttgtatc
//
LOCUS       DAVLHB010000007        61554 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLHB010000007 DAVLHB010000000
VERSION     DAVLHB010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61554
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.007"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..115)
                     /locus_tag="VXE36_000503"
     CDS             complement(<1..115)
                     /locus_tag="VXE36_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0778861.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLG"
     gene            complement(379..1545)
                     /locus_tag="VXE36_000504"
     CDS             complement(379..1545)
                     /locus_tag="VXE36_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0778862.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(1553..2647)
                     /locus_tag="VXE36_000505"
     CDS             complement(1553..2647)
                     /locus_tag="VXE36_000505"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0778863.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            complement(2804..3349)
                     /locus_tag="VXE36_000506"
     CDS             complement(2804..3349)
                     /locus_tag="VXE36_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778864.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     TDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            complement(3385..3924)
                     /locus_tag="VXE36_000507"
     CDS             complement(3385..3924)
                     /locus_tag="VXE36_000507"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778865.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            complement(3933..4478)
                     /locus_tag="VXE36_000508"
     CDS             complement(3933..4478)
                     /locus_tag="VXE36_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778866.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            complement(4650..6608)
                     /locus_tag="VXE36_000509"
     CDS             complement(4650..6608)
                     /locus_tag="VXE36_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0778867.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(6812..8434)
                     /locus_tag="VXE36_000510"
     CDS             complement(6812..8434)
                     /locus_tag="VXE36_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0778868.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            8540..9985
                     /locus_tag="VXE36_000511"
     CDS             8540..9985
                     /locus_tag="VXE36_000511"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0778869.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(10031..10225)
                     /locus_tag="VXE36_000512"
     CDS             complement(10031..10225)
                     /locus_tag="VXE36_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0778870.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVSKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(10326..10934)
                     /locus_tag="VXE36_000513"
                     /pseudo
     CDS             complement(10326..10934)
                     /locus_tag="VXE36_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(10959..11471)
                     /locus_tag="VXE36_000514"
     CDS             complement(10959..11471)
                     /locus_tag="VXE36_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0778871.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(11557..12492)
                     /locus_tag="VXE36_000515"
     CDS             complement(11557..12492)
                     /locus_tag="VXE36_000515"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0778872.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(12563..12862)
                     /locus_tag="VXE36_000516"
     CDS             complement(12563..12862)
                     /locus_tag="VXE36_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0778873.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(12852..13601)
                     /locus_tag="VXE36_000517"
     CDS             complement(12852..13601)
                     /locus_tag="VXE36_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0778874.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(13655..14014)
                     /locus_tag="VXE36_000518"
     CDS             complement(13655..14014)
                     /locus_tag="VXE36_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0778875.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(14016..15416)
                     /locus_tag="VXE36_000519"
     CDS             complement(14016..15416)
                     /locus_tag="VXE36_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0778876.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(15711..15950)
                     /locus_tag="VXE36_000520"
     CDS             complement(15711..15950)
                     /locus_tag="VXE36_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0778877.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(15982..16452)
                     /gene="ssbA"
                     /locus_tag="VXE36_000521"
     CDS             complement(15982..16452)
                     /gene="ssbA"
                     /locus_tag="VXE36_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0778878.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(16464..16754)
                     /locus_tag="VXE36_000522"
     CDS             complement(16464..16754)
                     /locus_tag="VXE36_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0778879.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(16907..18253)
                     /gene="asnS"
                     /locus_tag="VXE36_000523"
     CDS             complement(16907..18253)
                     /gene="asnS"
                     /locus_tag="VXE36_000523"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0778880.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIICATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(18410..18634)
                     /locus_tag="VXE36_000524"
     CDS             complement(18410..18634)
                     /locus_tag="VXE36_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0778881.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            complement(18627..19814)
                     /locus_tag="VXE36_000525"
     CDS             complement(18627..19814)
                     /locus_tag="VXE36_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0778882.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEKRLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(19811..20299)
                     /locus_tag="VXE36_000526"
     CDS             complement(19811..20299)
                     /locus_tag="VXE36_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0778883.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            20620..21168
                     /locus_tag="VXE36_000527"
     CDS             20620..21168
                     /locus_tag="VXE36_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0778884.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(21405..27563)
                     /locus_tag="VXE36_000528"
     CDS             complement(21405..27563)
                     /locus_tag="VXE36_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0778885.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKEDVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPRVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAKGEKGDRGER
                     GLTGAQGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGAQGERGLTG
                     AQGAKGEKGAQGERGLTGAQGAKGEKGDQGERGLTGAQGQAGRDGVTPTVTVKDNKND
                     GTHTITINDGRGNVTSTVVRDGFDGASPLVATQRNDADKTTTVIFYYDKNGNNELDAS
                     DKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITI
                     NDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEV
                     VIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDG
                     KTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDG
                     KEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEK
                     GAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQGERGLTGAQGAKGAKGEQGLQG
                     RDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARP
                     GQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVED
                     GQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKV
                     NPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERG
                     LTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNW
                     DKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDDHSTDITFTVPGKDPVTVNVKDGENG
                     LNGKTPKVDLLRVQGKNGNPFHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGAD
                     GRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEA
                     GHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTIT
                     TPGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRATDAAATPTRNGIRVTVYDD
                     VNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVVNSDGTTTTT
                     TVRDGREPKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTI
                     VDSDGREYKSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDG
                     KSPKVSVEDNGDGSHTITIINSDGTVTKTVIKDGKDGRDGRDGRDGKDGKDGKCGCQD
                     KPVTPSNDKPVPPTPNVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKE
                     NRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            27779..29263
                     /locus_tag="VXE36_000529"
     CDS             27779..29263
                     /locus_tag="VXE36_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0778886.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILEGLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            complement(29314..30042)
                     /gene="yaaA"
                     /locus_tag="VXE36_000530"
     CDS             complement(29314..30042)
                     /gene="yaaA"
                     /locus_tag="VXE36_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0778887.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(30121..30285)
                     /locus_tag="VXE36_000531"
     CDS             complement(30121..30285)
                     /locus_tag="VXE36_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0778888.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            complement(30464..32059)
                     /locus_tag="VXE36_000532"
     CDS             complement(30464..32059)
                     /locus_tag="VXE36_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778889.1"
                     /translation="MKRIVCELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(32071..32481)
                     /locus_tag="VXE36_000533"
     CDS             complement(32071..32481)
                     /locus_tag="VXE36_000533"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0778890.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(32597..33388)
                     /gene="yghU"
                     /locus_tag="VXE36_000534"
     CDS             complement(32597..33388)
                     /gene="yghU"
                     /locus_tag="VXE36_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0778891.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(33401..36097)
                     /locus_tag="VXE36_000535"
     CDS             complement(33401..36097)
                     /locus_tag="VXE36_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0778892.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            36401..37585
                     /gene="mntE"
                     /locus_tag="VXE36_000536"
     CDS             36401..37585
                     /gene="mntE"
                     /locus_tag="VXE36_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0778893.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(37728..39599)
                     /locus_tag="VXE36_000537"
     CDS             complement(37728..39599)
                     /locus_tag="VXE36_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0778894.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMVNQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(39596..40780)
                     /locus_tag="VXE36_000538"
     CDS             complement(39596..40780)
                     /locus_tag="VXE36_000538"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0778895.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(40792..41559)
                     /locus_tag="VXE36_000539"
     CDS             complement(40792..41559)
                     /locus_tag="VXE36_000539"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0778896.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(41825..42673)
                     /locus_tag="VXE36_000540"
     CDS             complement(41825..42673)
                     /locus_tag="VXE36_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0778897.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(42675..43049)
                     /locus_tag="VXE36_000541"
     CDS             complement(42675..43049)
                     /locus_tag="VXE36_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0778898.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(43123..44475)
                     /locus_tag="VXE36_000542"
     CDS             complement(43123..44475)
                     /locus_tag="VXE36_000542"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0778899.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(44499..45278)
                     /locus_tag="VXE36_000543"
     CDS             complement(44499..45278)
                     /locus_tag="VXE36_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778900.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEASITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(45265..46122)
                     /locus_tag="VXE36_000544"
     CDS             complement(45265..46122)
                     /locus_tag="VXE36_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0778901.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            46258..47226
                     /locus_tag="VXE36_000545"
     CDS             46258..47226
                     /locus_tag="VXE36_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0778902.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNEKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(47259..48170)
                     /gene="whiA"
                     /locus_tag="VXE36_000546"
     CDS             complement(47259..48170)
                     /gene="whiA"
                     /locus_tag="VXE36_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0778903.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(48167..49144)
                     /locus_tag="VXE36_000547"
     CDS             complement(48167..49144)
                     /locus_tag="VXE36_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0778904.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(49141..50031)
                     /gene="rapZ"
                     /locus_tag="VXE36_000548"
     CDS             complement(49141..50031)
                     /gene="rapZ"
                     /locus_tag="VXE36_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0778905.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(50083..50463)
                     /locus_tag="VXE36_000549"
     CDS             complement(50083..50463)
                     /locus_tag="VXE36_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0778906.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(50474..51061)
                     /locus_tag="VXE36_000550"
     CDS             complement(50474..51061)
                     /locus_tag="VXE36_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0778907.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(51070..52302)
                     /gene="clpX"
                     /locus_tag="VXE36_000551"
     CDS             complement(51070..52302)
                     /gene="clpX"
                     /locus_tag="VXE36_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0778908.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(52334..52504)
                     /locus_tag="VXE36_000552"
     CDS             complement(52334..52504)
                     /locus_tag="VXE36_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778909.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(52504..53010)
                     /locus_tag="VXE36_000553"
     CDS             complement(52504..53010)
                     /locus_tag="VXE36_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0778910.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFGPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(53140..53658)
                     /locus_tag="VXE36_000554"
     CDS             complement(53140..53658)
                     /locus_tag="VXE36_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0778911.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(54155..55659)
                     /gene="lytC"
                     /locus_tag="VXE36_000555"
                     /pseudo
     CDS             complement(54155..55659)
                     /gene="lytC"
                     /locus_tag="VXE36_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            complement(55697..56455)
                     /locus_tag="VXE36_000556"
     CDS             complement(55697..56455)
                     /locus_tag="VXE36_000556"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0778912.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(56553..57230)
                     /locus_tag="VXE36_000557"
     CDS             complement(56553..57230)
                     /locus_tag="VXE36_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0778913.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(57239..58183)
                     /locus_tag="VXE36_000558"
     CDS             complement(57239..58183)
                     /locus_tag="VXE36_000558"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0778914.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(58365..58877)
                     /locus_tag="VXE36_000559"
     CDS             complement(58365..58877)
                     /locus_tag="VXE36_000559"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0778915.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(58964..59722)
                     /locus_tag="VXE36_000560"
     CDS             complement(58964..59722)
                     /locus_tag="VXE36_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0778916.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKFAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            59930..60076
                     /locus_tag="VXE36_000561"
     CDS             59930..60076
                     /locus_tag="VXE36_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778917.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            complement(60223..61353)
                     /gene="ugpC"
                     /locus_tag="VXE36_000562"
     CDS             complement(60223..61353)
                     /gene="ugpC"
                     /locus_tag="VXE36_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0778918.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
BASE COUNT        17508 a        13987 c        11293 g        18766 t
ORIGIN      
        1 ttcctaacaa gcctgcaatt tcacgattgg acttattttc attcttccac cgctcaatca
       61 agcgacggtt atctattgtc aaatgtttcc cttttggggt ataatgttct tgcatctctg
      121 tgcctttcct tgtgtttgtg gtgaacaaca agtatagcac agaggtgttt tcttatacct
      181 taaatcacat ttcatttgac aacaggaacc cttgaacctg ttttttcagc taaaccaagg
      241 ctatgattag ccttggccac ctagcctaac agtttcaaac ctgttatcaa atgaaatcat
      301 caacttactc aaacatagtg aaacatctaa ttcttgacta aggtaaggtg gctaacttca
      361 ttatagaact ttcaattttt aacgtttggc aaaagtagcc acaatccgct gacagacttc
      421 ttgcaacaga gatttgggca tagctatatt gatgcgggca tggagacttc cttcctctcc
      481 aaaatccaaa ccacggttga ggataacctt ggcttcattt ctcaacaact cttgcaatgt
      541 ttcatcagtc aggtcataag ctgaaaagtc aagccaaatc aagtaggtac cttgcggttt
      601 catgaccttg attttagtct cttttccaaa tagatccacc acataattga tgtggtcttc
      661 aaagacttgc ttgagttcct ctagccaatc tttaccgtat cgataggcag cttctgtcgc
      721 caaataaccc aagcctgaaa tttcatgctg attattggcc aacaggcgtt tctggaaagc
      781 tagtctcaac ttaggatttt caatgactgc ataggaattt tttgttccag caatattaaa
      841 tgttttagtg gcactgctca agacgatagc aaaatttttg aaggcaggat tgatggtatt
      901 gaaagactgg tgtttgtgac caaagagggt caaatcttgg tgaatctcat ccgaaactaa
      961 caaaacaccg tgtttttggc agagttggcc aatcttctcc aacacttctt tttcccaaac
     1021 acgtccacca ggattgtgag ggttgcaaag aatatagagt ttaacctcct cttccaccaa
     1081 atccttttca agttggtcaa agtcaatctc aaacagacca tccttttcca ctaaggaatt
     1141 agtaatcaat ctacgattat tcaacttgac actgcgagca aagggtgggt agacaggcgt
     1201 gttaattaaa accgcctcgc cttcttttgt aaaggtttga atagctgttg agatggctgg
     1261 taccacaccc tcgataaaga caagagcctc tttgtcaaag ttgtaaccgt attgtgtagc
     1321 ttcccacttt tgaacttcct taattaagtc ttcactggca taggtataac cataaaccag
     1381 ttggtctgcg taagtttgca cggcttggcg gatttcaggc aagaccacaa agtccatatc
     1441 cgctatccaa gctggtagaa cttcactatc cgtttctgtt tctttccatt tataggtatg
     1501 gtgccctaaa cggttgggca ggcttgtaaa atcatatttt cccatctttg tcttatcctt
     1561 ctatggcttg gcgcaaatct gcaatcaaat ctctagcatc ctcaatccca atagacaaac
     1621 gcaagaggtc atctgtcaaa ccataagaat ggcgtacctc tgctggaata tcagcatgag
     1681 tttgagtcgt tggataagta ataagacttt ccactccacc caaactttcc gcaaaagaga
     1741 agaccttgag actgttcaaa atatgaggaa tgcgtgtttc atcggctact ttaaaggaaa
     1801 tcatgcctcc acgaccagtg tagagaactt ccttaactgc tggagaatcc ttcaaaaagg
     1861 caaccacttc ttgggcgtta gctgttgagc gctccatacg aagagacaag gtcttgagac
     1921 cacgaagcaa ctggtagctg tcaaatggag acaagactgc ccctgttgta ttaagattgt
     1981 aaaaaagctt ctcgtatagt tctaaactat tggtcacaac cactccagcc aagacatcat
     2041 tgtggcctgc tagatacttg gttgctgaat ggagaacgat atctgctcca tcttcaatcg
     2101 gacgttggta gatagggcta tagaaggtat tgtccaccac cactttggca cccttagcat
     2161 gagccaattt tgctagtttt tcgatatcaa attccaacat caagggattg gttggggttt
     2221 cgatatagag aacatccaca tccttttcta actcggcaat caactcttct tctgtattgg
     2281 cataggtaaa atggaaacga ccttcctgct ccacttggtt aaaccagcga aaagaaccgc
     2341 cgtaaagatc acgcactgcc aagaccttac ttcctactgg aaagccgcta aaggccagta
     2401 caatagctga catccctgag ctagtcgcta aggcatagtc tgctgactca atagtcgcca
     2461 agacttcctc agccttacta cgagttggat ttttagtgcg cgtatagtca aacccagtag
     2521 atcgaccaaa ctctggatgc tgataggtcg ttgaaaaatg aagcggtgtc accaatgcac
     2581 ctgtcgcttc atctgactta atacccgcct gggccaaaat tgtgttaatg tgtaattcct
     2641 tgctcataca atacctccaa atctatagta actattgtac cacttatttt catcaactca
     2701 ttttcttctt ttcaagagct agttatagtt tcaaactata taaaaaggga gtttttcctg
     2761 ctccctttaa tagactataa aatggtgaat ctcaaaagac acttcactct atcatttgct
     2821 cctgcacaaa acgagcataa cgctcatgat tttccagtag ttccttatga gttcctgagc
     2881 cagtgatttt cccctcctct aagaagaaaa tacaatccac atcttttacc gttgacaaac
     2941 tatgcgctat aatcacaacc gtcttctcct ttaatacaga atagaggcta ctgataatcg
     3001 catactcaga atccgcatca agattagcag tagcttcatc aaatataaga atttcagcat
     3061 cttttaagta ggttctagct atttgaagtc tttggctttg cccccctgac aagaatcgtc
     3121 cgcgttcacc aacttcagta tctagtccct ctttcatgga gcgaatctca tcacctagtg
     3181 atactaagtc tagcactttc atcaattcat catcagttac taagcgattc aaaccgagac
     3241 aaagattgtc acgaatactg ccagataaga ctgcattatt ttgtgaaacc caagcgattt
     3301 tacttctcca ttcttttaag ttaaaatcat atatacttga ttgctccatt agaatatctc
     3361 ctgaaagcgg tttataaaac cgctctaaca aacgcacaat cgttgatttt cctgatccag
     3421 atggtccaac aaaagcaatt tttgcccctt gaaaattgaa caagtaatat cctttaagac
     3481 aggtcgattt tcatcataac caaaatagac atggttaaaa ttcaaccctt gtcctgatac
     3541 cgattttcct ccctcaaatt tttctttagg aactgcaagc aagttatcca gtgcaactga
     3601 agatcccttg ctcctagaat aaacagttac aaaattagct atattactaa taggattaag
     3661 taattgaaag aggtaaatca aaaacgaaac caaggttccc acagatatat atcctgcgct
     3721 gacccgataa cccccatagg ttagcatcac agctatagtc gcaaagataa ataagagagc
     3781 aaacggggtc tcaaaagaag taaccctatc tgatttcagt gaattgtttt gtaccctttc
     3841 aatacaatta tccaaaacat cctgtacact tttctctgct tggttagtct taattaattc
     3901 atgttcttga atcttttcag tcaattgccc tgttaaattt cctcctgtaa acgacgacta
     3961 tacttttcac tgatattgga aaggggcaag ataataaaca tcatacaagg aagagtgatg
     4021 aataaaagta gagaaagatt ccaatcaaga ctaaataaga ctacaatgga accaagtacc
     4081 ataactaaac tcagaataat atttgggaaa gtcgtaatta aaaactcacg aatgacactc
     4141 atgtcattga caatggcaga agtcaactcc ccactttggc tcttatcaaa gaaggatttc
     4201 tctgcataaa tcaacccctc tatcactttt ttcctgattt ttgctatctt tttttcaccc
     4261 gattgactaa acagatagta accaatagaa gaaaacaagg cttgaccaat aaaaatcaaa
     4321 aacgattgaa atactttgga acctatattt tcaatagaac tcccatctat taaacccttt
     4381 aagataaggg gaagcaacaa agcaagtaga ctagacagaa caagtaagaa actccccata
     4441 atcaccttag tatctactct taataatttt aatttcataa atactcctta taatatttca
     4501 acggataaag tcgggaataa ctcaatttga ggataaaatc taataaatct tcctataaca
     4561 aaacgcataa catctaggat tttatatacc tgatattatg cgtttttaag cacaaagact
     4621 tcttacacaa acttatctac aattagattt tatttgacat gttttgccaa ttcttcttgg
     4681 gcttttttat tggattcttc tttttctttc aaccattttt ctctggcttt tgcatattcg
     4741 tctgttgtga caatcttatc ttgtactttg aggtatttat atgattcaac cccttttgta
     4801 ccggttaaac cataggcagc agcaaatggt acggttcttc tcaatgatgg tgttccccca
     4861 cgcgaaacac ttggaagaac taaagaacta tcaatcaacc aagcttgaat atcagcatat
     4921 ttctcataac gtttggctgg atcttgctct ttattagctt cttccaacat ttgagtatag
     4981 acatccagtc caactgcctt agccttgtca ttggcttctc caggctctag tccaagattt
     5041 tgtagaactc ctccactatt agtattaaaa atatcgagat aggttgacgg gtcttgataa
     5101 tcaggtcccc aaccgccatg atataaatca tagtctttct gagcagctgt ttgagcaaag
     5161 tagcctgaac tgtcaaactc atctgatgtt aattgctgaa tgtcaatcac tacattatca
     5221 gaacctaaaa cagattcaat tgattgtttg atagaactaa ctccttgtat gcctacttta
     5281 tctgttactt ccacagtctt atccaagtgg attgggaatt gaacaccctt tgcttcgagt
     5341 tctttcttag cttccgcaaa cttagccttg gctttctcag gattgtaata agggtcttga
     5401 ccatccgcaa agttgatacc ttgccattcc ttaccatagt tgaccatctt agaggctaca
     5461 acttcaccaa agtcttttcc cttgatactg acaaagtttg gaggaaccac taggttacgc
     5521 aaaatctttg ttgcaccttc tttcccttca gactgagccc cataagatgt tctgtcaaaa
     5581 gcaaaattga tagcctgacg gaagttttta ttgagaactg cttcctgggt cgatttcttt
     5641 tcaatgtcac ttgttttaga agtataattg taagacttcc tatctaggtt aaaattaaag
     5701 aaatatgaag ttgaattttg catactatag atgatattgt ttttgtattt ttctttaatc
     5761 ccttcatagc tggagctgtt aggaaaaaga cgagccgtag tataagcacc agctgtaaaa
     5821 ttacgttcca gtgattcttg gtcgctacca tcatagtagg tcaatttcac atcgtctaca
     5881 aagacattct tagcatccca gtaattaggg tttttcttat attcaatagc agattttgag
     5941 acaagtgctt tcatcaagaa aggtccattg tacaaaatac tagatggatc cgccttccca
     6001 aaatcatccc cttttgattt caggaaatct gcattaacag gaaaaagtat cgttgcaagt
     6061 gtttttgaat tccagtaaag ttctggttta accaaagtat attgaaccgt ttggtcatca
     6121 agtgccttga caccgacagt tgaaaagtcg cttgttttac cagtgatata gtcatccaaa
     6181 ccagcaacag agtcctgcac tagatacaaa gcttctgatt ttttatcagc tgcatattgc
     6241 aaacctgtca caaaatcctg ggcagttaca ggcgcatatt cttctccctc agaagtaaac
     6301 cacttggcat ccttacgaag tttgtaggta taggtcaaac cgtcctgaga aacagtccaa
     6361 tcctctgcta atgatggaat aatattccca tattggtcat tttctaataa cccgtctacc
     6421 aaatttgcaa caatatcgga tgttgctgcg cggttttctg ctagatagtt caaactagat
     6481 ggatcacttg aataaacata gttataggtt tttgatgcag tgctagaatt tccacacgcg
     6541 ctcaataaaa ctcctgtacc caggacaaga cctgccaagg ttagatattt gctcttagac
     6601 tttttcattt ccagaacctc ctgctttaaa tatttgtttt attatacaac tcttggtttg
     6661 tttagtcaat tgtttttttc caaaaaatca aaaaaacctc attttctatt tttgaaagat
     6721 aattttagct attttgacgc taaaaaagga ataagtttca agttctccta aaagattgtt
     6781 caacttattc cttttattta taaatgctac cttacgaaag cttaaatttt gctcgcaggc
     6841 gatctgcttg ggcttttcct attaccttat ctaataaata ggtacgcaga ctcataacca
     6901 tataaagtcc accccccatg gcaccgacaa gagctacata aaagaagctc cacaaacgtc
     6961 cacttggttg gaagaaaaat cctaacagcc actggatggt tcctattaac agaaacatga
     7021 ctagggtcag caaactgatt aaaatggttc gcttcaaaat caccttgcgc ttgacaccag
     7081 ttactttaca aatatcccga tacatcaaga cgttaggaat gatgagagca atggttgttg
     7141 aaatcaaagg accataactg tggaagaggg cgatggtagg tagttgcaag actagcttgg
     7201 caatagaacc atagataaaa tagagaacgg ccttgcggtt gcggaacatg gcctgaagca
     7261 ttggagacaa gaccatgtac aagcctaaaa taatagactg caaaactgca aagacaaata
     7321 agcccagagc caaactatct ggcttaccat agaagaccgt ataaagaggt tctcctacca
     7381 taaccactcc aaccgttgct ggtagcaaga acataaagag tagggtgaga ctgtcctgaa
     7441 cgagacgaga agctgctttc aagtccccct tgacatagtt ttccgtcaaa agtggcaaac
     7501 caacactccc aatcgaaacc cctacagaaa tcaaaatcat cgtgatttta ttaggattgg
     7561 ctgagaaata agaaaacatg acaaccaagt cctcattgct gtagttggta aaccagctca
     7621 tactattgat aaaggtcagc tgatccaaaa tctggaagag ctggatggca gaccctgtca
     7681 ggataaaagg aatggcttcc ttaatggtat caaccaagag acgcttactg ttaatcttat
     7741 ctcctgtttc aaagactctt ttgagtgaac cttcttgggc aaggaaataa atcaagactg
     7801 caaaactggc taccataccg acaaaggcag caaaggttga ttgggtaacg gctgctagat
     7861 aatctcctga accgagcttc ataatgataa aggttgctag gagcatccag ataacacgaa
     7921 tgacctgctc agcaatttgg ctcatggcat agggtttgag gttattcatc ccttggaaaa
     7981 atcctcggat aacactcata gacgggaaaa tcaagactcc ccaagccaag ctttgcatga
     8041 ttgggatcaa gtctttgccc acgccagaca agtctgctag ccaaggagca aagacataca
     8101 agactaaagc aaaaaccagg cctagtcctg tcataaagcc taagaagctc cgaatcaggg
     8161 caaagctatg ctcttcttct cgcatggtat tatacttggc aacttgcttg gccaccgcaa
     8221 ctggaatccc cgctgttgaa accaacaaga accaagcata gatattgtaa cccatggtaa
     8281 agagaccatt tgccttagct gcataagccc ccatccagat gtaccaaggg ataatgtaaa
     8341 cagccccgag taggcgactg ataaagttac tagccgttag ccaagcagtc ccccgtaaca
     8401 tctgggcctg ctggtgattg ttttcgtgcg acatagattc ctcattcaat tttgataact
     8461 aggaaaaact ccttatcttc cattataaac ttttccttgt tacttgtaaa tttgcgactt
     8521 tcggtttaca atagaaagta tgataaaaat tgaaactgta ttagatattt taaagaaaga
     8581 tggccttttt cgcgaaatta ttgaccaagg tcattaccac tacaactaca gcaaagttgt
     8641 ttttgatagc atcagctacg acagccgaaa agtaacagaa gacactcttt tttttgcaaa
     8701 aggcgctgcc tttaaaaaag aataccttct ttctgctata acacaaggct tagcttggta
     8761 tatagctgaa aaggactacg aagtcggtat ccctgtcatc attgtgaacg atataaagaa
     8821 agccatgagt ttgattgcca tggagttcta tggtaatcca caggaaaaac tcaaactcct
     8881 tgcctttact ggtactaagg gtaagacaac agcagcctat ttcgcctata acatcttatc
     8941 tcaagggcat cgacctgcta tgttgtcgac catgaacaca actcttgatg gagagacttt
     9001 ctttaagtca gcgttgacaa cccctgagag tattgacctc tttgacatga tgaatcaggc
     9061 tgtgcaaaat gaccgtaccc acctcatcat ggaagtctcc agtcaagcct atctggtcaa
     9121 acgtgtctat ggtctaacct ttgatgtggg agttttccta aatatcagcc tagaccatat
     9181 cggcccgatt gaacacccta gctttgaaga ctatttctac cacaagcgtc tcttgatgga
     9241 aaatagccga gcagtcatca ttaacagtga catggaccac ttctcagtct tgaaagaaca
     9301 ggttgaagat caagaccatg atttctatgg tagccaattt gataaccaaa tcgagaattc
     9361 caaagccttt agattttcag ctacgggtaa actcgctgga gattatgata tccaactcat
     9421 tggcaacttc aaccaagaaa atgcagttgc tgctggactt gcttgtctcc gtctcggagc
     9481 aagtcttgag gacatcaaaa aaggcatcgc tgcaacccgc gttcctggtc gtatggaagt
     9541 cctcactcag aaaaatggag ccaaggtatt catcgactat gcccacaatg gggatagtct
     9601 gaaaaaactc atcaatgtgg ttgaaactca tcaaaccgga aagattgctc tggttctggg
     9661 atcaacagga aacaagggag aaagtcgtcg taaggacttt ggcctcctcc tcaatcaaca
     9721 ccctgagatt caagtctttc tgactgctga tgaccctaac tatgaagacc caatggccat
     9781 tgcagatgaa attagtagct acatcaatca tcctgttgag aagattgcgg atcgccaaga
     9841 agccatcaag gcggcaatgg ctatcacaaa tcacgaatta gatgcagtta ttattgcggg
     9901 taagggagcc gattgttacc aaatcatcca gggcaagaaa gaatcctacc caggagatac
     9961 agccgtcgca gaaaattatt tataagaata gaaaaaatca agggaaaatg aaacccttga
    10021 ttttttccta ttatttagta aaaacgtttt tcaaaccttc aacggcacct tctacagcac
    10081 cttttgcgtc ttctacaacg tcttttgcct tagaaactgt tttttcaaca gctccttcaa
    10141 gttctgtctt gctgtctcca gtaactttac caaaaccttc tttgacagcg cctgttgctt
    10201 gttccaattt gttttcaagt gacatatgat tgtctccttt agtttattcc gatatgtgtt
    10261 accggttaca tatagtttat accgaatact aaggaaagtc aaacaatgta ctcagaaaca
    10321 agaaatcacg ctaagtagaa agttaacctc tccttatcaa aatcgatagc caactcatac
    10381 tttccatctt cattttgcac aatatagcct aagacaacct aactgtccac aaagatatca
    10441 cggcatttct gcataagctg gtcttttttg agaaatttca acaaaaaagc cgtcatatac
    10501 ttgagggcat actcaggatt aacatctcct aaaatgtcat agagctcctg ctgtttttct
    10561 gtcaaaggat actgctgttt gaccttgtaa aaataattgg acagggtcat tttaatgcgc
    10621 gcaaagtccg tcttttcaac taaaatagct gcattgattt gattgcgcaa ttccgtctca
    10681 aaactctgct ccaacaaggc ttgatagacc ggactagctt ctctgacaaa aatctcttga
    10741 tccagttcaa gactatcaag tgattcaagc gtaggaaaat tgaggtaata gcgcttattt
    10801 tcacgtagaa tcaagcctgc ctttatatac tcttccatga gtttatcaac tgcaacatct
    10861 ggaaattgag ccttaatttc ccgtagaatc acatcctcat actgatccag atagcggatc
    10921 aattctccaa aaatggctgt ctcgtcaaac gagatggatt aaaaatctga atcatgaaga
    10981 ttcctttctt tacattgtaa cagaggcgat gctgccaact gactaggatt ggtaccagct
    11041 tggttcagag gaacaggcag acctagttct atgtaatact ccctccaaaa atcactaatc
    11101 tcctgctccc catctccaaa tttcatagga atagtttcaa aaataggtag gatttctgct
    11161 atatactggg agcagtaaaa accagctgca tctggataga aagaagcatt gtagggtgct
    11221 ccaagatgtt tgcaagctct ttccttcacc gactggatat ccatttctgg gtaaacatag
    11281 aggtcgtata aatgattgga ctcaaagaag tctgccggtt cttgacagac aacaccagcc
    11341 tgtccactag catgataaat catcccatcc aaataaatgg caacatggct atagttacct
    11401 gtggaagtct ggatggcctg tcccatgtct gacccatctc tcacaaaaat caaatcgcca
    11461 ttttctaaca tacttcactc ctagaaaaaa ggagccgaaa ctcctttcga tataaggcaa
    11521 actagacttt ccgattttga gctgacaccc aaaatcttac gcattaaagc tttcagtcaa
    11581 ttgaggtacc acttgtttct tacgtgaaac ggcaccagca aggaaggcat gattgttttc
    11641 aagtttgaag ttgaaagccg cttcgacctt gtccatattg gcaccaagag ccaagatttc
    11701 tgagtttgag ttgacgatat ctgtaatcat caagacaaag tcagagtagc cgtttgattc
    11761 gttggcagct tgcattgcag cttcaatttc tgcttggcgt tccaaaactt cagcgatgtc
    11821 aactgtgttc acttgggcaa cacggacatt atttccgttg agttcaaaag tcttagcatc
    11881 gatatcaatc aattcttcag cagatttgct agccaagttg gtaccagctt tcaacattgc
    11941 caaaccatat tcttccaagt tcacaccagc caattcagcc aattcaggag caatgatttt
    12001 atctgttggg tgtgttgttg gtgatttcaa aagaagggta tctgaaatca aacctgaaag
    12061 catcaaacct gcaatctctt taggcacagc tacaccatgt tctttgaaca tacggtaaac
    12121 gattgaagac gctgatccaa ctggctccaa acgcatgtaa agtgggcttg cagtttcaaa
    12181 gttagccaca cggtggtggt ctacaacacc gtaaacttct acttcagcga tatctgatac
    12241 agattgttgg aattcattgt ggtcagtcaa gataacttgc tctgccccct ctgctttggc
    12301 agaagtgata acacgtggtg cttccacacc aaaatagttc aagacaaagg ctgtttcttc
    12361 atttggagtt ccaagggcaa cagcttccgt atccaaaccg taagcttctt ttgcaaggta
    12421 ggcaaaagct acagatgatc cgatggcatc tgagtctgga ttttggtgac caaatactag
    12481 aatcttggac atgataatac ctcattttgt ttattttctt tattgtagca tttttttcgc
    12541 tttttgacaa aggtaagagg agtcaaagga ctccccacga ttcttcaaaa taactgagta
    12601 aatttctatc ttgattttca gataaaaatt cttccttctg tggcctcttc ttacgcttga
    12661 gaagagcttc agccgacatg gcttcttcct tactggcaaa accttgagca tagataagtt
    12721 tgactggcaa gcgtgctcgt gtatatttgg ctcccttccc actattgtgg atagcgaggc
    12781 gtcttctcat atcagtcgta tagcctatat agtaggatcc atcacgacac tccagaacgt
    12841 acatataagc cttatgatcc ataataaatc tcttcgattt cgggcgtata agagccatca
    12901 tcattgtgga caatcaaagg aggtaagacc ttaaagccac ttgttgagcc atccttgatc
    12961 gcctcaatca aaagcatatt ggcttccttt tctctttttg gataaacaaa ctgcaggcgc
    13021 ttaggggcta gattatgtcg ttttaacgta tccaaaatat ccagaagtcg atcaggacga
    13081 tgaaccatgg ccaaacgccc attagacttg agaatactct gggcactacg acagatttct
    13141 tccaaattag tcgtgatttc gtgtcgagcc aagagataat gttcactctc gttcagatta
    13201 gaataaggat ccaccttgaa atagggtgga ttacacaaaa tcatatccac cttactcccc
    13261 tgaatgtgag caggcatatt tttcaaatca tcgcagatga cctgcatttg ctcctctaat
    13321 ccattcaaac ggacagagcg ttcagccata tccgccaaac gctcctgaat ctcaacagac
    13381 aatatctgtg cttgagtacg agtgctagca aaaagcccca ctgctccatt cccagcacag
    13441 aaatccacaa tcaacccctt cttaggaaaa cgtggaaatc gtgataagag aacactatcc
    13501 accgaatagc taaaaacctc tctattttga atgattttga tatctgtcga aaagagctgg
    13561 ttaatgcgct ctcctgattt taataattgt tcttcttcca tggtcctatt atagcaaatt
    13621 catattaaca ttacaaaaaa tataaaactc taaactactt cttctttttt aaatggtgca
    13681 gggcttctcc agtccagatt ggtagcattc gtcgaaaggg agcaaaaccg tagttaaagc
    13741 ggtcgcttga aaagcgtctc cgtctaggaa actggtactt ttcttcctcc aaagtgcgga
    13801 tagaaagact ggctttcccc gtaaattcat ctaaatccac tacctgaact tgaacctctt
    13861 catcgacttt caaggtttca tgaatatttt caataaatcc tgtccgaatt tctgaaatgt
    13921 gaatcagccc cgtatcaccc gtctctaact caacaaaggc accgtagggc tgaatccctg
    13981 taatacgccc ctttagctta tcaccgattt tcatcttagt cctcgatttc aatagtttca
    14041 attacaacat cttcaactgg cttgtccata gctcctgtct caacagcagc aatggcatcc
    14101 aagacagcgt aagatgcttc atcagctaac tgaccaaaaa ccgtgtgacg gcggtctagg
    14161 tgaggtgtcc caccttgatt ggcatagatt tctgcaatcg gttctggcca accaccacga
    14221 gtaatttctt tcttagaata aggtaggtgt tggttttgca cgataaagaa ctggctgccg
    14281 ttggtatttg gaccagcatt tgccatggaa agagcaccac ggatattgta aagctcttct
    14341 gagaattcat cctcaaaaga ttcgccgtag attgactggc cacccatacc agttccagtt
    14401 gggtctccac cttggatcat aaagtccttg ataatacggt ggaaaatgac accatcatag
    14461 tagccatctt ttgaaagaga tacaaagtta gccactgttt taggagcatg ttcagggaaa
    14521 agcttgatac gtaagtctcc gtgattggtc ttaatagtcg caagaggacc ttctactgtt
    14581 tcaatgtcta cttgtggaaa atgcaattct ttttctacca taccaaatac ttctaaggca
    14641 gcaaaaatgc catcttcttc taatgttttt gtaatataat ctgctttttc tttgatttta
    14701 tcatgagaaa ttcccatggc aacgctgatt ccagcataat caaagagttc caagtcgttg
    14761 agaccatctc caaaaaccat gaccttctct ggtttcaagc caaggtgttc cacaaccttt
    14821 tccacccccg tcgctttgga gcctgaaatc ggcacaatat cagacgaatg ttgatgccaa
    14881 cgaaccatac gaagtttgtc tgagagactg tcaggcaagt gcaagtcatc tcccttatct
    14941 tcaaaagtcc acatctgata gatatcttct ttttcatgga aatcgggatc tacatctaag
    15001 tcgggataaa ttggattgat agcttcactc atcatatcgg tgcgagtcga caacttggca
    15061 tcatgactcc caaccaagcc atactcaatt ccttcttgct tagcccaaga gatatactcc
    15121 tcaacatctg acttttcaat ctgatgctga taaatgacct gacctttttt atcttcgata
    15181 taagccccat tcaaagttac aaaaaagtca ggcttgagat cacgaatctc tggaacaaca
    15241 ccaaaaatgc cacgtccaga ggcgattcct gttaaaattc ctttttcacg caactgttta
    15301 aaaacagtgg ggattgtagt tggaataaac cctgtctttg aattccgcaa tgtatcatca
    15361 atatcaaaaa agacaatctt gatcttcttt gccttgtatc ttaatttcgc gtccatctca
    15421 ctacctcttt caatctaact ctttccatta tatcataaag taggcaaatc ccctattttc
    15481 aaaaagttta tcatttttat tttaatttct tggatgagaa aagagacata tttatgaaaa
    15541 agctccatcg tgcttttaat gtgttctctt gttttcaaac tcgtaaaaag ggagccactg
    15601 agcctaactc gctctctcat ttcaaagctt gtgaaaaaag acccgttggg gtcttaattc
    15661 gctttcttgt tttcaagctc atgaaaaaga gacccaaccg ggtcttttct ttaatcttcg
    15721 tttacgaaag gcatcaaagc cattacgcga gcgcgtttga tagctgttgt tactttacgt
    15781 tggtttttag ctgaagttcc tgttacacga cgaggaagga ttttcccacg ttctgaaacg
    15841 aaacggctaa gaagctcagt atctttgtaa tcaacatatt caattttgtt tgctgcgatg
    15901 taatcaactt ttttacggcg tttgaatccg ccacgacgtt gttgagccat gttttttctc
    15961 ctttataagt ttagttgtcc attagaatgg taaatcatca tctgaaatat ccaatgggtt
    16021 tgttgctcca aatggatttt cattacgtga aaagtctggt actgaatttg taggtgctga
    16081 atagtttgca gttggtgcag agtaagctcc acctgtgtga ccctcacgca cactacggct
    16141 ttccaacatt tggaaattct cagccacgac ctctgtcacg tagacacgtt gtccttgctg
    16201 gttatcgtaa ctacgagtct ggatacgacc tgtcaccccg ataagtgagc cttttttagc
    16261 ccagttagca agattttcag cctgttggcg ccacataacg acattgataa aatcagcctc
    16321 acgttcacca ttttgactct taaatgtacg gtttactgca agagtaaaag tcgcaactgc
    16381 tacatttgat ggggtataac gcaactcagc gtcacgtgtc atacgcccta caagtacaac
    16441 attgttaatc atagtttacc ttcttacgcg tcaattttga cgatcatgtg acgaagaatg
    16501 tcagcgttga tttttgaaag acggtcaaac tctttaagag ctgcatcgtc atttgcttca
    16561 acgttaacga tgtggtaaag tccttcacgg aaatcttgga tttcgtatgc aagacgacgt
    16621 ttttcccaag tttttgattc aacaacagtt gcaccgttgt cagtcaaaat agagtcaaaa
    16681 cgtgctacca aagcgttttt agcttcttct tcaatgtttg gacgaatgat ataaagaatt
    16741 tcgtatttag ccattgatat gttcctcctt ttggtctaat gaccccaaga ctttgcaagg
    16801 ggtaagtgag gttcgctcac aataaactat tatactagaa aaaatttttt tacgcaagta
    16861 aaaacactag aattcgaaaa aacgccacat gggcgttttc ctgttcttat ggtttgatac
    16921 ggtgcaacat acgtgggaat ggaatagctt cacggatatg ttttgttcct gctgcaaagg
    16981 ttaccatacg ttcgataccg ataccaaatc ctccgtgtgg aactgtaccg tatttacgaa
    17041 ggtcaaggta gaattcatat tctgtacgat ccataccaag ttcatccatc ttagcgacaa
    17101 gggcatcgta atcttcctca cgcatagacc caccgataat ttctccatag ccttctggag
    17161 caagcaagtc tgcacaaagc acgcgctctg gatttccagg aactggtttc atgtagaagg
    17221 ccttgatggc tgctggatag ttcatgacaa atgttggcac accaaagtgg tttgaaatcc
    17281 aagtttcgtg tggtgaccca aagtcatcac catgctcaag atgctcgtag tcagcatctt
    17341 catcattttc atgctcttgc aagaggtcaa tggcttgatc gtaagtgata cgtttgaatg
    17401 gctctgcaat gtagcgtttc aagagttctg tatcacgttc caaggtttcc aaggcttgag
    17461 gcgcgcggtc aagaacacct tgtagaagag ctttcacata agcttcttgc aagtcaagcg
    17521 actcatcatg tgtcaagtat gagtactcag catccatcat ccagaactca gtcaagtgac
    17581 ggcgtgtttt tgatttttca gcacggaaaa ctggaccaaa gtcaaagaca cgaccaagag
    17641 ccatagcccc tgcttctagg taaagttgac ctgattggct caagtaggct ggcgttccga
    17701 agtagtcagt ttcaaagagt tctgtagaat cttctgccgc atttcctgaa agaattgggc
    17761 tgtcaaactt cataaaaccg ttcttgtcaa agaactcata agttgcacag ataatagcgt
    17821 tacggatttg caacacagct acttgcttac gagagcgtag ccacaagtga cggttatcca
    17881 tcaaaaagtc tgttccgtgt tcttttggtg tgattgggta gtcttgagat tcaccgatca
    17941 cttcgatgtc tgtgatgtcc aactcatagc caaatttaga acgttcgtcc tctttgacaa
    18001 tacctgtcac ataaacagac gtttcttggc tcaagcgttt gataacatca aacttctcaa
    18061 gtcccacttc ttcaccaaat ttttcgacaa agtttggttt aaaagccaca ccttgaaaga
    18121 aggctgttcc atcacgcaat tgtaagaagg caattttccc ttttcctgat ttattggcaa
    18181 cccaagcgcc aatcgtcact tcctgaccaa catagtcttt tacgtcaata atcgttacac
    18241 gttttgtcat tatttttcct tttctttttt attctttatg gcaaaccacc tctatattgt
    18301 tcccatccag gtcaatcata aaagcagcat agtaaatcgg acgctcactt cgataaccag
    18361 gagccccatt gtctcgccca cctgcctcta agccagcctc ataacaagcc taaacttctt
    18421 ccttattttc tgctaaaaaa gcaaaatgaa caggatcttg tgttccctga gtcagccaaa
    18481 aatcaccacc aggatgaggg ctgttcgggg atagaaaact aattagagaa ctagtcttaa
    18541 aagctaattt atagtccaaa ggagcgagaa aactcctata aaatccttct gaaatttgta
    18601 aatcctttac cttaatctca aaatgatcaa tcattctcac tacccataaa tgctttcaag
    18661 cgttcgactg cttctttaag cgtgtctagg tctgtcgcat agctgaggcg gacattttct
    18721 ggtgctccaa atccagctcc tgttaccaag gccacttcgg cttcttctaa gatagcagtt
    18781 gtaaagtctg tcacatccgt gtagcctttc atctccatgg cctttttgac atttgggaag
    18841 agatagaagg ccccttgtgg tttgaccact tcaaatcctg gcacctctgc aaggagggga
    18901 tagatggtat taagacgttt ctcaaaggcc tgacgcatgc tttctacagt atcttgctca
    18961 cctgatagag cctcaactgc tgcatattgg gctactgctg acggattcga agttgtttga
    19021 cctgcaatct tggacatggc agcgataatg tctgcttctc caacggcata accaatccgc
    19081 caaccagtca tggcataggt tttagacaca ccattgatga ccactgtttg cttgcgaatc
    19141 gcttccgata ggctagaaat cggtgtgaac tcatgaccat tataaaccaa gcggccatag
    19201 atatcatctg ctaggatgag aatatcattt tctacagccc agtttccaat tgccaagagt
    19261 tcctcacggg tgtaaatcat acctgtggga ttagatggcg aattcagcac caaaaccttg
    19321 gtcttgtcag tgcgagctgc ttctaactgc tctacggtca ccttaaagtg attgtcttcc
    19381 ttagcagaaa caaagacggg aacgccttct gccatcttga cctgatctcc atagctaacc
    19441 cagtatgggg ttgggatgat gacttcatca cctggattga ccaccgccat aaagaaggta
    19501 tagagagaat atttggctcc cgcagcgact gtcacttgat ttgacgctac agaatagccg
    19561 taaaagcgct caaagtagct attgaccacc gccttaagct ctggcagacc tgaggttact
    19621 gtataaaaag aagcacgccc atctcgaatc gatgcaatgg cggcatcttg gatatttttg
    19681 ggagtagtga aatctggctc acccaaggtt agagacaaaa tatctctgcc ctcagccttc
    19741 agtgctttgg cacgggctcc agcagccaaa gtcacacttt cttccatttc taaaacacgg
    19801 ttggataatt tcataggccc tccttgttga ccaatgctcc tgtttcaaaa tctactagat
    19861 aaaaatcaga tcctgacttg acttcccaga ttggcttatc ttgataacga ccaaagataa
    19921 tcttgtcaat ttcgccagct cccttttcct tagaaaccgt ttctgctttt tcttgtgaaa
    19981 caccctgatt tagctgataa acgtaaatct tatgatcatc ttttccaatc agaacagcaa
    20041 gtgcttcttg ctgtttatta cgaccaagaa cgctgtaata agattccaag ccattgtata
    20101 aatcaacctg atcggcctgc tctaatcctg catactgctg agctaatttt tctccttcac
    20161 ttttagctgt ttgatagggt ttcatgctaa gagaaaccat atacagaaag gaagcactga
    20221 taaccacaaa caaaatcgtc atccctagac catactgcca cagtagatta ttttttgctt
    20281 tgttttgtct ttttttcact cgtctatttt accatctatt aagctttatt acaagtgaat
    20341 ataagaatac tcttcgaaaa tctcttcaaa ccacgtcagc tttatctgca acctcaaagc
    20401 tgtgctttga gcaaccaatt ctatttctcc cttcaaacaa aaccgatttt gaaagtgaaa
    20461 cagttcttac tttttcagtc acaaatgact agagtttccg aaattttaca attttcaaat
    20521 aaactctgag caaatttctt gcaagttctt ttgttttgtt gtaatatatt ttataacaac
    20581 gagagagttc tcgaaatttt aagaaaaagg agacacatca tgtctaaaaa agtattattt
    20641 atcgtcggat cactacgtca aggttctttc aaccaccaaa tggcgctcga agctgagaaa
    20701 gcacttgctg gtaaagcgga agttagctac cttgattatt cagcccttcc tctcttcagc
    20761 caagatttgg aagttccaac acatccagct gtagctgctg ctcgtgaagc agttctcgtt
    20821 gcggatgcta tctggatttt ctctccagtc tacaacttct ctatccctgg tacagtgaaa
    20881 aacttgcttg actggctatc tcgtgccctt gacttgtctg atacacgtgg cgtttctgcc
    20941 cttcaagaca agtttgtcac agtatcatct gtagccaatg cagggcacga tcaacttttc
    21001 gctatctaca aagacctctt gccatttatc cgtacacaag gcgttggtga tttcactgct
    21061 gcacgtgtta atgactctgc ctgggcagac ggaaaattgg ttcttgaaga aacagtccta
    21121 aactcacttg aaaaacaagc tcaagacttg gtcgaagcga ttcagtaaaa aatagaaaat
    21181 tttagaaagt ctaaatcaat tatagccacc taatagggtg gctttttatt tctcaatcaa
    21241 gattttcaga caaacatcag ccatccaaaa aaaccttgag cgttaccact caaggttttt
    21301 agcagtcttt tccatcatag gaaaatcatt ctaagaatat tctttcattc gagatctatc
    21361 acttatcatc ttctttcgag aaattagtga ctgcttttgg ctgattaatc ttcttttctt
    21421 cgtcctacat ataggctcaa tagaataccg ctacctaaaa gaacagagat ataatcagat
    21481 tggcttccag tttcaggtaa tttgtcccca cggttttctt tacctgtagt tggtgctact
    21541 gggttagcat ttactggagt tgctggttga gccggtgttg gtactactgg ttgttctgga
    21601 accgctggta ctggtttaac cggtacttct ggtgtcggca catttggtgt tggaggaact
    21661 ggtttgtcat ttgatggtgt tactggtttg tcttggcatc cacattttcc atctttaccg
    21721 tctttgccgt ctcgaccatc acgtccatct ctaccatctt tgccatcttt aataactgtt
    21781 tttgtcacag ttccatcaga attgatgatt gtgattgtat gactaccatc accattatct
    21841 tcaacagaaa cttttggtga tttaccatct ttaccgtctt taatcaccat ttctgtctta
    21901 cttccatctg gattagtgat tgtaacaacg tgagttccat cgttattatt tttaacagtt
    21961 acagttggtg aaacgctatc tttgccgtct ttaccatctt tgataataga tttgtattca
    22021 cgaccatcag aatctacgat tgttaatgta tgagttccat ctccgttatc aacgatgttc
    22081 gcttttggtg atttaccatc aaagattgta gttgtcgttc ctttaccatc agcacctgtc
    22141 actttaatag tgtgtgaacc atcgttgtta tcaataactt caagttttgg ttctctacca
    22201 tcacgaactg tagttgttgt agttgttccg tctgagttca caactgtgat agtgtgagtt
    22261 ccatctccat tatcttttgt agtaatagtt ggagctgaac catcacgtcc atctataccg
    22321 ttataaatat ctttactatt taatacttta tcgacacctt cgtcgtatac cccattgtca
    22381 ttaacatcat cataaactgt aacacggata ccgttacgcg ttggagttgc agcagcatct
    22441 gtagcgcgtc taattcttga aggtgaagta atatcttcta ctttgatttt cggtgcacgg
    22501 ccatctttac cattcttacc atcttttaca gtgaaggtta ctggatcttt acctggtgtt
    22561 gtgatagtta caacagtgct ttggccatct tgtccacgtt gagtagtgat tgtaggagtt
    22621 tgtccatcct gaccggttgc accagtttct cccttagcac catcttgaac aaagactgta
    22681 gttggttgtg aaccatcatg gttatcaaca gtgatttcta cacctttatg ccctgcttca
    22741 tctttacgaa cagctgtaac tgtaggtgat tttccatcta ctccatctct aattaccgca
    22801 agtggttttt ctggatttaa tggttgtcct gggttagctg gatcttcttg gtaaacttta
    22861 gtttctttac catccttgac agtaagcaat gatttaccat ctcgtccgtc cgcgccttta
    22921 gcaccatctt taatcatttc tgaacctaga agttcatcag ttcctggtgt atatttaccg
    22981 tcattgtttt catctgtata gaatgtcaca attgtatgaa atggatttcc gttttttcct
    23041 tggacacgaa gtaaatcaac ttttggagtt ttaccgttca gaccattttc tccgtcctta
    23101 acatttactg taactggatc tttacctgga acagtgaatg taatgtcagt actatggtca
    23161 tctttacctg gagttacagt tacttctgga gtcttaccat cttctccgcg ttcacctttg
    23221 tcacccttag ggcctttgat gttgccctct ttatcccagt tgccgttatt cttaacgaag
    23281 acgtcgcctg tttctgtatt aacgtattta tcgccgtctt taccttgatg tgcttctggg
    23341 ttagctttgc cgttcaacac gtctttaccg tcacgtccat cacgacctac tgcgccatcc
    23401 gcacctttag ctccttgcgc tccagttagg ccgcgttcgc cttggtctcc tttttcgcct
    23461 ttagcaccat ctgcaccttt gtccccttta gggcctttga tgttgccttc tttatcccag
    23521 tttccattgt ttttaacata gacatcaccg gtttcggtat taatatattt atctccattt
    23581 ttaccttggt ttggttgtgg atttactttt ccgtttaata catctttacc atcacgacct
    23641 gcttgtcctg tagctccatc acggatcgta gttgtcacat ctggacttcc tggattatga
    23701 accgttaatg tatgtgtgcc gttttgcccc tcagttattg ttactgttgg ggttttccca
    23761 tcagcaccct tttgtccatc ctctacaaat gttgtttgtg gacgacctcc tactggtgta
    23821 attgttacta atacaccatt tttgccattt tgcacacttc gtgtcgctgt aattgttggt
    23881 gattgtccat tagtaccgtt tcttccatca gtgatagttg ctaatggttg gtttggatta
    23941 agtggttgtc ctggtctagc cggatcctct acatagactt ttgtttcagt tccattttta
    24001 acagcaatta gagattttcc atctttacct ggagttcctg gattaccttg ttctcctttt
    24061 ggtccttgtg gtcccgctgg tcctctttgt ccatctgcgc cttttggtcc ttgagctcca
    24121 tcacgacctt gaagaccttg ttcacctttg gcacctttgg caccttgcgc tccagttaaa
    24181 ccgcgttcac cttggtctcc tttttcacct ttagatccag ttagaccgcg ttcaccctga
    24241 tctccctttt cacccttgac accttgcgct ccagtcaggc cgcgttctcc ttgggctcct
    24301 ttttcaccct tggcaccatc tgcacctttg tcacctttcg gtcctttgat gtttcctgct
    24361 ggttcccaag tgttaccttt cttaacgaat acatctcctg tttgtgtatt tacgaatgtg
    24421 tctccatctt taccttctgt tgttgggtct acttttccgt ttaatacttc ttttccatca
    24481 cgtccagatg ctcctgcagc tccgtcttgt ccgtctttaa ctactgttgt ttgaactaac
    24541 tcgtcttttc ctgctgtgta acttccatct ccatctttgt caatgtagaa tgttaatgtt
    24601 gtttgtttct tcgcatcatc tcgttctgct ttgacttttg gtgtttttcc atcttcaccg
    24661 tttttaacga ttgttgttaa tgatggtctg ttgtctggtt gtgtgattgt gatggtgtgt
    24721 gttccgttat tgttatctgt aactgttact tctggtgtga atccatcttt tccgttatca
    24781 cctttgtcac cttttggtcc ttgttttcca tctgcaatta caacttcttt aagttttgta
    24841 tctccttcat caaattgatt attatcattt agatcataat agaaaataac agttgttgtt
    24901 ttatctgctt catttctatg agtagaaaca agagggcttg caccatcaaa tccatctctt
    24961 actactgtag tagttatacc acctttacca tcgttaattg taattgtatg cgttccatct
    25021 tgaccatcag ttactttaac tgttggggtt ttcccatctt ctccttttgg tccttgttca
    25081 ccatcacgcc cttgaagacc ttgttcacct ttgtcccctt tttcaccttt agcaccatct
    25141 gcaattacaa cttcttttaa tttcttatca gaagcatcta attcattgtt tccattttta
    25201 tcgtaataga agataacagt tgttgtctta tctgcgtcat ttcgttgagt cgcaactaat
    25261 ggacttgcgc catcgaaacc atctcttaca acagtacttg taacattacc tctaccgtcg
    25321 ttaatagtga tagtatgagt gccgtcattt ttattatctt taacggttac ggttggagtt
    25381 acaccgtcac gacctgcctg accttgggct ccagtgagac cgcgttcacc ttggtcccct
    25441 ttttcacctt tagcaccttg tgctccggtt agaccgcgtt caccttgggc tcctttttca
    25501 cctttagctc cttgagctcc agttagaccg cgttcacctt gggctccttt ttcaccttta
    25561 gctccttgag ctccggttag accgcgttca cctcggtctc ctttttcacc tttagctcct
    25621 tgagctccag ttagaccgcg ttcacctcgg tctccttttt cacctttagc tccttgagct
    25681 ccagttagac cgcgttcgcc tcggtctcct ttttcacctt tagctccagt tagaccgcgt
    25741 tcaccttggt ctcctttttc acctttagct ccatctttaa tagcaatttt ttgaacaagt
    25801 tcgtctacac cttcagtata aacaccgttt ccatcgttat caagatagaa agtgaggtta
    25861 tttgtatcac cgactttatt ttgatcaaca cgtggtttta ctgtatcgat tagatcttta
    25921 gccacaccaa tttgcataat acgtggctta gcttctttag taacactatt actaatcggc
    25981 aatcctaaaa gtgtttcgtt accaaatcga tgaactttat aggtaatttg acgttgtcct
    26041 ttttcacctt ctcgaactaa tctagtttga ccttctggta acttactagt tggaagatag
    26101 acagtttgga agtcaatgtc ttctgaaaca gtcttattat tagtaccacc ataagggttt
    26161 gcatccaagt atagtgggtt tgctctataa taatagttag agttactgta tgggtcattg
    26221 ctagtagcgg caccaccacc accttggtcc acgttaaaag taacaggttt caaacgaaca
    26281 gacaaatcac catttagatt aatgataggc aaactaaatc tgatagtttg ttccgtattt
    26341 gttgaaatag cagaggtcat actgtatcct gagtgagata cgtagttggc accctgacta
    26401 atagattttg attgctccct tactcttgga tttgaacttg tgatcgttgc atttgaagga
    26461 tttccaaatc catccccttt atccaagata aaattattat taacaaactc tctagaatct
    26521 cctggcgcag aataactaat tgtaaagtta acactattac cactacgtac tgttgttaca
    26581 tcgtaatgaa tagaatttcc accacgtgag ttcccgtagc cacggaaact atagctacga
    26641 ccaccttggc taatatctgc aaatgcaact gtatttccag aacctgagac aattgggttg
    26701 gctggattgc tagccgctct aaaaccacta taccctctat taacatcttc cttacggata
    26761 gctggatttt ggcgagcatc agaaaggctc aaacctagtt tcaagatttc attaatagat
    26821 gctggagctg aagttgtttc tactttgtca gctgtgctag ttggcaaaat agcgctatca
    26881 acagctgaac gttcagttgt tgcagctggt ttagcccctt cttttgattc aactgcatca
    26941 gctttcttcg ctacaggcgt ttctgataca gtttctttat tagagttaga acgaagttct
    27001 agaccaataa taaatgattg aatagatgac tctgctgctg ataattcagc ttcagttgca
    27061 tctgcttttc caagcaagct ttgaccagct tggatacttg tttgcaagtt agcagcactt
    27121 gcttctgtat ataacttgct ttctaatttt ttagcacgcg aaagagccgt taataatttt
    27181 gacttgtcaa cggcatcttg atgcgttact tcctcttttt tgtcttttgc ttcttcaact
    27241 ttttctgctg gtttagtaac ttcttcagtt ttaactggag tcgtttctac tggattagct
    27301 acagttggag ctgcataggt tttctcttta ttagacgcag aaacctctgc tggtttagta
    27361 gctgcttctc ccctaccaac agaaatacta ttggtagttt cttgtttgtt ttcttccgct
    27421 tgtactgttt ggacactagc tgctgcacct aataccaaag cggtaccgag caagacacta
    27481 gctgcaccaa agtaatactt acgaatagaa taacgttgtt gcatgctata ccagtcaaat
    27541 gattttttat gtgaatgttt cattttaaac tcctagatag tattttatag tttacaatgt
    27601 acaactattt gaggcattaa tcaatatttt ctgaacaatt aatatattct gtttttgcac
    27661 ttaaaagcca cttatattat tctaattttt ccgattacta acgacaattt tcttgctcta
    27721 atttttttat actacttaga caaaaaaaga tataatgaat tatggaggaa atacccgtat
    27781 gagaaacctt ttatccacaa aagttcaaag acaattacgc ttaatggaaa ccctaattca
    27841 gaatcgtaat tggatgaaat tacatgaact agccgaaaaa ttaggatgta cagaacgaat
    27901 cttaaaaagt gatttaaatg aattacgtat tgcctttcca tctattaaca tccaatcttc
    27961 tgttaacgga atcatgatag atttagaagt taacactagt gtagaagata tttatcaata
    28021 ctttcttgct aattctcaat cttttcaatt actagagtat atgttcttca atgaggggct
    28081 acctatttat cgaacaatag aaaatcttta ctttagtagt gccaacctct atcgactggg
    28141 cagaaatatt acaaaggttc tttcatctca gtttcaaatt gaattatctt ttactccatc
    28201 cgagatacgt ggaaatgaga tcgatattcg ttactttttt gcccaatact tttctgagcg
    28261 ctattatttc ctagattggc cttttcctga ccttcctgag gaagatttaa cagagtttgc
    28321 tgacttcttc tataaaatca caaattatcc aatgcgattt tcaatttata gaatgtacaa
    28381 actgatgata gctatcagta tccacagggt taaaaatggt cacttcattg acctccccaa
    28441 ccacttttac aaagaatatt atcctctttt aaagagcatt ccgaatttcc aggagacact
    28501 tgcttatttc tctaaacatt ttgggcttga aatgactcca gatacaatcg ctcaaatttt
    28561 tatttctttt cttcagaatg atattttcct agatcctcaa gaattcttca actctttaga
    28621 agataacagt caagcaagat actcttacca attacttagt caaatattag aaggcctatc
    28681 aaaacaatat aagattactt ttactaacca cgatgagctg atttggcatt tacacaacac
    28741 tgctttcttt gaaagacagg aaatcttttc taccccaatc ttatttgaac aaaaagcatt
    28801 gacgattaaa aaatttgaag tttacttccc agactttatg ggaagtgcgc gtcaagaatt
    28861 ggctcaatac cgtcaggcaa ttggacagca tgaccatcct gaacagttgg aacacttgat
    28921 gtacaccatc ttaacccatg ctgaaaacct ctctactcag ttgttagaaa atcgaccacc
    28981 tatcaaggtt ttgattatca gtaactttga ccatgctata tcccttacct ttgttgatat
    29041 gctttcctat tactgtaata accgctttac cttcgatatt tgggatgaat taaaaacaag
    29101 tcctgagatt ttaaatcaga cagattacga tatcatcgtg tctaatttct atattccagg
    29161 gattaccaag aagtttattt gccgaaatca tctgtcaatc atgaatttgg ttaatcatct
    29221 taacacctta tcaaatgaga ttcatttgtc caatacttta taagttatca aaaaagtcag
    29281 cataatcgtg ctgacttttc tcttatctga tttctatact tcctttacaa aaaccaatcc
    29341 ctgtggttgt gacaaatctt ctcggtaaac aaatccagca aagttcaagc gacgtgcttc
    29401 ccccacagtt tgtacttgat tttctattaa agctgttaga aaggccccgc gcgctttctt
    29461 ggagatagtt gagtgaatct tcagctgacc gcctctatcc tccatgaatt tgaaggtcac
    29521 catctttgct ctgatttcct tagaaaatac agtctcaaac tctgatgaca agagagagaa
    29581 aatcacttct tccttcttca gagcttcatc atagactgcc ttccaatggc tcttcaaagt
    29641 cttaccagcg acttttaatt tcatcaaaaa atccaaacgg tgaggagcca tgggtgacaa
    29701 ggctggaaca acaccgtaca aagccgaggt aatgaagaca tgattttcaa gataatcttg
    29761 ttccgcctcg gtcagcttat ctctcttaat gttgcggtac ataagcccat caaaaagttt
    29821 caaggctgga tagtgttgag cagtttgcct tttcaaagct tggatatttt gaaattcttc
    29881 cgccgctttc tcagctgata ccttgtagaa actctccaat tgactggcag aatagagagc
    29941 caaggcatca agcacggtct gactttctgg ttttaaagga attgcctcga tacttggcaa
    30001 gtctgtgttc atttcttttg ctgttgggat taaaattttc atattgatag tgtagcatat
    30061 tttttagcca caaccaagaa attcatttga aaaacctcgg tttgaccgag gtttttctat
    30121 ttatttgggc catcctaacc agacagccgc gagaacaagg gctatgccag ctaaacttgt
    30181 taagatagat aagaatttat cttttttctc cttgaactga gaaaaaccta tcttcaaagc
    30241 gagcagtccg agtagcattg aagcaaccat caaataaaaa cccatttctt tgtcctccat
    30301 taggcttaat ttaccttatt ataacatata tttcttaaat aaaccttttt tatactcaat
    30361 gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgc tcaaaacact gttttgaggt
    30421 tgcagataga gctgacgtag tttgaagaga ttttcgaaga gtattattgt actttaaagg
    30481 tcttgagata attgtctttt cctacttgac cttcgaaggt tttaccattt tcaaggtaag
    30541 gaaggtcatc ggatactgaa gccttgacct tgtatatctt gccatcaact ttaaagaagt
    30601 agacagtgtc tcccttgata acagctgatt tgaggtctgc tactactccc ttgatgcttt
    30661 ctgtcgttgc attgtcaatt tcaaggtcgt ttttattggc atacttgctg agcatctctt
    30721 ccactgtagt agcaacgata acattttggt actcgactgc gtctaccagg gcgtactctt
    30781 tgaccaagcc agcattgtcc tttaagccca tgatgtagag aggcttgtca ttgaggttga
    30841 tgaggattgg gaaggttgct ttgtaggatt tctcctgaac agcaccttct gctgattcac
    30901 gggctgattc ttctgtcgca gaagccaagc tatacttagt aatttctcct gttcgcatat
    30961 tttcaaggat gaaaccaaga ttactctcat ccgcattagc cgacgtcaca cctgtgtaga
    31021 gatagatgtc attaccgata gacaagtaat tatagccatt ggtagtctgg gtcacgtttt
    31081 tcttggaaat catggcattc aagaaaccgt ccttgtactt gccgttgtag ttgatttgct
    31141 caatggtttc ctctgctgga tagatcctgt ccacccattc tggaacatct gataagctgt
    31201 attccttggt ttctccattt gtagcatcca agataatgac tgaagcagga cgaggaaccg
    31261 caagtccaaa ttgcttttgg taaaccgttg ctacatagaa aggattgccc tcatcgtcca
    31321 cctcaaaaga tggagtttta aagattttag tcgggtactt caagcgcagg tgacgtttga
    31381 catcacggtt aaaatactcc gagtctgaat acttgattgg tgtcttcaag tccaccaaat
    31441 ccgcatttcc agttaccatg tccaccttga tatactcacc gattcccttg gcttgattgt
    31501 taaaccattt gatagggtct gcatattcta gtggtgtgac ccgataaggt ttcccatcaa
    31561 ttgtcaattg ggtataggta tctgccgcta cgtattgcga caccttatcg gttagggaac
    31621 ccaagtagcg gtctccaatt ttttcagcag tacttctatc taggatagga accttactgg
    31681 tgtcactcct aggaaattca gtaaagtctt tttccgtaac cgtgactaca ttggcataat
    31741 ttttagcctg aaacatgctg gaagttacca aggaaaccaa agctgccaag agaagaattc
    31801 ctccaatcga agctaacaga attttcccta accgattgat tttgaaaccc tcaagattta
    31861 aggcagcttc cgccttaccg tggcgcacat gaaccgtttt gacaaggttt atccccttgc
    31921 caaagccaaa taagattgcc acaactaaca aatgcccaca gaggaagaag agaaattccc
    31981 agctggtcag gttaaggggc ggtaaaaaga tataccaggt cgttgcgata aaaataagtt
    32041 cacagactat tcgtttcatt tgctttcctc ctaaatgatt cgtccttcca agtgatccag
    32101 ctcatgctgg caaatctgag ctgggaagcc tgtcaaggta atggtctgtt cctgccactt
    32161 gctgtcacga taggcaagcc ttgtggtttc ataacgctta gttgatctca cacctaccaa
    32221 ggacaaacag ccttcttctg cctcatagga tccttcaaag gacagaagca ctgggttaaa
    32281 catgaccacg ggaaccaagc caagattaaa gataatcacg cgcttctgca ccccaatcat
    32341 attggcagct agaccaacac aggtatcacg atttgctaag agtgtatcct gcaaatctct
    32401 ggcaagataa aggtcctcct gacttgccgg ctgagacact tgagataaaa ataagatatc
    32461 cttcacaatt ttcttttcca cttcctcaca ctcctcttgc tttttactat attatagcaa
    32521 ttatagcaca aaagccgata actgcaaacc ctttccctca actgtagcaa aaagccatcc
    32581 gaagatgact tttttgctat ttaatttctg tataagttac ttccaagcca cgcttaacag
    32641 ctggacgatt ggcaattttt tctgcccatt ttactagatt ttgataactt gaggcatcca
    32701 agaattttgc agaaccttgg taaagatttc cttgaactaa ctgtccatac caagaccaga
    32761 tagcaatatc tgcaatcgta tagtcattgc ctgcaatata aggtttctga gccaattcct
    32821 tatccaataa atccaactgg cgtttcactt ccatcgtaaa acggttaata ggatattcca
    32881 atttttcagg agcataattg aagaaatgtc caaatccccc acctagaaaa ggtgctgcac
    32941 ctgcttgcca gaatagccaa ttcaaaactt ctaccttttc cacaggatta cttggtaaaa
    33001 aggctccaaa tttctcagca aggtaaagaa gaatatgagc agactcaaag actcttacat
    33061 cttcagtacc tgactggtcc aataaggctg gaatcttgga atttggattg agcttcacaa
    33121 agtctgatcc gaattgatcc ccatccatga tagcaatctt atacaagtcg taagccgctt
    33181 ccttaaaacc agcttctagt aattcttcca ataagatagt aaccttcaca ccatttggtg
    33241 ttcccagtga ataaagctga aaagcttgtt ctccttttgg caagttttgt tcgaaacggg
    33301 cacctgctgt tggtctgttt agccccgtaa aagctccttg attactagct tcatcctgcc
    33361 atacggtcgg taattgatat gctgacatcc gagacctccc ttaaatcgca ttcttgtcaa
    33421 aaccgagttt gcgttgaata aacttaacga tttcgacgat gataatcatt gagaagcttc
    33481 cagccataac aattccccat tgtgacaagt ctagtttggt tacgtggaag attccttcaa
    33541 gcggttctac aacgattgtt gccatgagaa ggataaagga taccaagatg gaccagttaa
    33601 aggtcttaga cttgaatggg ccaactgtca agatggattg gtagacagac ttgacattgt
    33661 aggcatggaa gagctgaatc aaaccaaggg ttgcaaaggc catcgttagg gcatctgcat
    33721 gaatagcatg attgtcaccc acatgaactg ggtaagcaat cgcaaggcca taaacactca
    33781 taacaagagc tgcttggagt acaccttgat aaatgataga actcaaaaca ccacctgaga
    33841 agaagcttgc cttgcgtcca cgtggtttat gattcatgac accaggttcc gcaggttcaa
    33901 caccaagagc gatagctggg aaggtatccg ttaccaagtt gatccacaaa agatgaaccg
    33961 gctgtaagac atcccaacca aacaaggttg ataggaagat ggttaatact tcagcagtat
    34021 tagcagaaag taggtactga atagtctttt gaatgtttga gaagacctta cgtccttctt
    34081 ccactgcgac gataatagtc gcaaagttat catctgcaag aatcatatca gaagccccct
    34141 tagaaacctc tgtaccagtg attcccatac cgataccgat atcggctgtt ttcagagctg
    34201 gcgcgtcatt gacaccgtca cctgtcatgg caacgacttt accttgtttt tgccaagcct
    34261 tgacgatacg aaccttgtgt tctggagaca cacgggcata aacagagtat tgaccaacaa
    34321 ctttttcaaa ttcttcatct gacagttcat tgagttcagc accagttaaa acgtgacctt
    34381 ctgtatcgtt tgcgtcaatg attcccaaac gtttggcaat ggcttccgct gtgtcttggt
    34441 ggtcacctgt aatcataatt ggacggattc ccgcttcctt agccacacga acagcctcag
    34501 cggcttcagg acgttcaggg tcaatcatcc caatcaaacc agtaaaaatt aaatcatttt
    34561 caagctcttc agaagtgaga ttttctggaa tgctgtcaat aatcttataa gcacctgcaa
    34621 ggacacgcaa ggcttgatga gccatttcag agttgtttgt atgaatgaga tttgtaacct
    34681 tctcatcaat cggagcaata tccccagcct tatcacgaag aagacaacgt tttaagagtt
    34741 ggtctggcgc acccttgact gctacaagga aacgaccatc tggcaatggg tgaactgttg
    34801 acatgagctt acggtcagag tcaaatggca attcagctac acgaggatat ttctctaaga
    34861 aacctttgac atcatagccc ttgtccaagg catattggat aaaggctgtt tcggttgggt
    34921 caccaatcaa gttaccttcc acatcgattt tcgtatcatt ggccaagaca actgaacgaa
    34981 gtagtggcat ttcaagacct agttcaatat catcagctga gtcatgtaga accgcatcgt
    35041 agaagacttt ttcgactgtc atcttgttca tagtcagcgt accagtctta tcagaagcga
    35101 tgatttcagt tgaaccaagt gtttcaactg ctggcaactt acgaacgata gaatgtcgtt
    35161 tggccaaaac ttgagtacca agagaaagaa cgatggtaac gatagcagga agtccttctg
    35221 gaatggctgc aacggcaagg gcaacagaag tcaacaactc accaagtgga tttttccctt
    35281 gaatgaagac acccactaca aaagtaacaa gggcaatgac caagatagca taggtcaaga
    35341 ccttagaaag gttgttcaaa ttttgtttga gtggtgtatc agtctcatcc gcatcttgaa
    35401 gcataccagc aatatgacca acttcagtgt acatacctgt attgacaaca acacccatcc
    35461 cacgaccata ggttacgttt gagttttgga aggccatgtt gacacggtca ccaataccag
    35521 catctgtcgc aagctcgact gacaagtctt tttcgactgg tacagattca cctgtcaagg
    35581 ctgcttcttc aattttaaga gagttggctt ctatcaaacg taggtccgct ggtaccacgt
    35641 cacctgcttc aagggcaacg atatcgcctg gtaccaattc tttagagtca atctctgcca
    35701 tgtgtccatc acgaagaacg cgggcaactg gactagacat ggatttgagg gcttcaatag
    35761 cttcttcagc ttttccttct tggtaaacac caaaggcagc gttgatgata accacagcta
    35821 ggatgataat ggcatctgcg atatcttccc caccagaagt cacgactgac aagattgctg
    35881 ccgcaactag gatgataatc atcaaatcct taaattgctc gatgaatttg accaagattg
    35941 atcgtttctc gccttcttcg agttcattgt gcccaaattc ggcaaggcgc ttttccgcct
    36001 cacttgatga caaaccttgc tcggtcgcat ccacagcctg caagacctct tcagggctct
    36061 gagtataaaa cgcttggcgt ttttgttctt ttgacatgtg tctcctcctt gacattgtgt
    36121 gcaaaacaga ctctctttct gtcatatctt ttcacgacaa acaaaaagag acctgttaat
    36181 cataacaagt ctcgctgttt aagatagggc cggaaagcat acttttcagc ataaaattcg
    36241 gaatgacgac actatcacag gtttctgcca gctactccct tgagtagtac cattatacca
    36301 aattttgggg agttttcaaa gagtaaaaac tgccttattt gaatttttcc ttgaaaacca
    36361 gtataatggt agaatgctat gtgactagaa aggaagttga atgaagcaat ctatctcaaa
    36421 tctcaagtta gctgagcgtg gagccattat cagtatttcg acctatttga tcttgtctgc
    36481 agccaaatta gcagctggtc atctccttca ttcatccagt ttggtggccg atggttttaa
    36541 taacgtatcg gacatcattg gaaatgtggc cctcttaatc gggattcgga tggcgcgcca
    36601 gcctgcagac cgtgaccacc gttttggtca ttggaagatt gaagatttgg caagcttgat
    36661 cacttctatc atcatgttct atgtcggttt cgatgttcta agagatacca ttcaaaagat
    36721 tctcagtcgg gaagaaacgg tcattgatcc tcttggtgca actctaggaa tcatttctgc
    36781 agcgattatg tttgtggtct atctctacaa tactcgcctc agtaagaaat ccaactccaa
    36841 ggcgctgaag gcagctgcta aggacaatct ttctgacgct gttacctcac ttggaaccgc
    36901 cattgccatc ctagctagta gtttcaatta tccgattgtg gataaactgg ttgctatcat
    36961 catcactttc tttatcttga agactgccta tgatatcttc atcgagtctt cctttagtct
    37021 ttcagatggc tttgacgacc gcctgctcga ggactaccaa aaggctatca tggaaattcc
    37081 caaaatcagc aaggtcaaat cgcaaagagg tcgcacctac ggtagcaaca tctacctgga
    37141 tattacacta gagatgaatc ctgacttgtc tgtttttgaa agccatgaaa tcgcggatca
    37201 ggtcgagtct atgctggaga atcgttttgg cgtctttgat accgatgtcc atatcgaacc
    37261 agcacctatc cctgaggatg aaattttaga caatgtctat aaaaaattgc ttatgcgtga
    37321 acaattgatc gaccaaggaa accaactaga agaactcttg actgatgatt ttgtctatat
    37381 tcgccaagat ggagagcaga tggataaaga ggcttataag accaaaaaag agttaaattc
    37441 tgctatcaag gacattcaaa ttacttccat cagtcaaaaa accaaactta tctgctatga
    37501 gttagatggt atcatccata ccagtatctg gcgtcgccac gaaacctggc aaaatatctt
    37561 tcatcaagaa accaaaaaag aatagagaaa tcctttcatg agacgggatt tttctattcg
    37621 tttatactca ataaaaatca aagtgcaaat taggaagccg gtcgcaggct gtacttgagt
    37681 cggcaatgtg aagccgacat agtttgcact ttgattttcg aatagtctta actatcaaat
    37741 tcactgagat actcatagcg ttcgtatttt tcaaggagtg cttcattttt ctcatccaat
    37801 tctttttgga gagtagccag cttaccaaag tcagagccgt tagcctgcat ttcctcttca
    37861 atagcagcga tacgtttttc caaggtttca atatcacctt caatacttgc ccactcctgc
    37921 ttttcttggt aggtcatgcg tttcttgtct tctcgaacct tgaccacttt ttccttttcg
    37981 accttttgca cttgattgac catatctgtt tcaaaagctt tttcatcaag atagtcggtg
    38041 taatgaccaa agaaaggacg aatcttgcca tcctcaaaag cgagaatctt ggtcgctacc
    38101 ttatccaaga aatagcggtc gtgactgact gttaaaacgg gacctgcaaa accttgcaag
    38161 aaattctcta agactgtcaa agttgcaata tctaggtcat tggttggctc gtctaaaaga
    38221 agaacatttg gtttttccaa aagcagtttg aggagataaa gacgtttttt ctcaccccct
    38281 gacaatttct caatcaaggt tccatgcgtc gaacgtggga aaaggaactg ctccagcaac
    38341 tctgcaatcg aagtcgtaga accgccactg gtcttgacct cctctgccac ttcctgcagg
    38401 taattgataa ctctcttgct ttcatccaaa ccctcaattt gctgagagaa ataggcgatg
    38461 cgaacagttt ccccaatcac aacttgtcct ttagttggct caagacttcc tgcaatcaag
    38521 ttgagcaggg ttgattttcc aacaccattg tccccaacga ttccgatacg gtctttggcc
    38581 tgcaccaaga gattaaaatc ttgcaaaata ggcttgtttt cataggcaaa ggaaacagcc
    38641 tgaaactcga tgactttctt cccaatccga ctggtttcaa agttcatggt caagtctgtc
    38701 tcagcactac tgcctgaaac ttcctttttc agatcatgga atcgattgat acgggcctgc
    38761 tgcttggtcg cacgcgcctg cggttgtctg cgcatccagg ccaattcttg tttgtagagt
    38821 tgttcttttt tgtgaagaag agccgcgtcg cgctcatcct gttccgcctt taggcgaaca
    38881 tagtcctggt aatttccctg gtactcggtc aagcctgcac gatccaactc gaaaatccgt
    38941 gttgacaaag cgtctaagaa ataacgatcg tgagtgataa aaaggacggt cttcttagaa
    39001 tttttcaaaa agagggtcag ccactcaata atcgcaatat ccagatggtt ggtcggctca
    39061 tccaaaagca agaggtcgtg gttgccaagt aagacttgtg ccaactgtac ccgtcttctc
    39121 agaccacctg acaattcccc aacaggagta gataagtctt gaatgcccaa tttgctaaga
    39181 acggtcttga cctgactttc gatttcccaa gcttggagag agtccatctc tgccatgaca
    39241 cgttccaaac gcgcctgctt gtcctcacta tagtcgagca taatcaattc atactcacga
    39301 atgagctgga tttccttgag ttcactagat agaaccgtat ccaaaactgt ctttctatca
    39361 tcaaaatcag gatcctgagt caagtaacca atctggtaat catttttagc tgaaaaagga
    39421 ctgacatccc catcaaatcc agaaacacca gaaaggacgt ccaaaagggt ggtcttgcca
    39481 gtcccattga caccgattaa accaattctg tctaagtcat ggataataaa ggaaatatcc
    39541 ctaaaaacgg tcttgtcacc aacggattta cttagttttt caacgataaa atcactcatt
    39601 ttttctccct caggtaagca tggatggctt cacgattatt ctccaattct ccatcgacaa
    39661 tggcaaactc aatctctgtt aaaatctctc ccaagtctgg gcctggctga tagccatatt
    39721 ccttgatcaa aataccgcca ttaatctgaa tctctttctt gtcatggata gtcaagcttt
    39781 ggtatttttc tgtgatggct tgtgggttga cttcttttcc ttgagcttga cgaagatttt
    39841 cagcctgtaa aagcaaatct atgtcaaagc gataacaatc tcgcttgctc aattctccat
    39901 tttcacgcag agccaaaata atcagcaaat cctgaacttg cttggcaaac tggcgtgagg
    39961 tcttccaaga tttcaaaaat gactgcgcat tttcaatctc caaagcccat agtaaagccg
    40021 cccaggcttg ttcagaggat tcaaaagtaa aatcagtctc caaatcaaac agtctgttga
    40081 gcttgtcctg gctagatgcc atatcaggga gatagtcata agcttgactc tcaatcatgg
    40141 aagccaagcc ccttctccaa aatggagcca gcaagagttt atcaaactcg acgaaggtac
    40201 gctctacaga aattttctcc aaaagcggcg tcaaggtctt catagcttta aatgtttctg
    40261 gttcaagtgc aaaaccaaga ctagcctgaa aacggaaacc acgcataatc cgtaaagcat
    40321 cttcgttgaa acgctcacta gccactccaa ctgctcgcaa gacttgcttt tccaaatctt
    40381 ctaaaccatg gaacaagtca acgatttctc ctgtctcatc caaggcaaag gcgttgactg
    40441 tgaaatcacg gcgtttgagg tcttcttcta gcgagcgcac aaaggaaacc gcactgggtc
    40501 tgcgatagtc cacatagaca tcctctgtcc gaaaggttgt tacctcatac tcctcatccc
    40561 catctaagac caagacggtt ccatgctcga ttccgatatc ggctgttcgc ggaaaaatct
    40621 gcttggtctc ttctggataa gaagacgtcg caatatccac atcgtggata gggttatgga
    40681 gaagggcatc tcgaacagag cccccaacaa aataagcctc aaagcctgct tctttaattt
    40741 tttctaatac tggtaaagcc ttctgaaatt cagaaggcat ttgcgttaat ctcataataa
    40801 gtgttctaat ccatagacaa gctcatgacg cttgacaact tctttaattc ccaaattgac
    40861 tcctgtcatg aaggagatgc gatcatagga gtcatgacgg agggtcaacc cttctccctg
    40921 attgccaaag atgacttcct gatgggctac caaacctggc aaacgaactg agtggatgcg
    40981 cataccatca aagtcagcac cacgagcacc agcaatcagc tcttcctcat ctgctgcgcc
    41041 ttgctgaatg gactctcgaa cctctgccat caactcagct gttttaatgg ctgttccact
    41101 cggagcatcc tttttcttgt catgatggag ctcaataatc tccacatttg ggaaatattt
    41161 ggcagcctgc gtcgcaaatt gcatgagtaa gacagcaccc aaggcaaagt taggggcaat
    41221 caggccaccc aagtcttggg cacgagaaaa ttcttttagc tctgcaattt cttcactcgt
    41281 gaaaccagtc gttccaacta ctggagcaaa gccattttca agagcaaaac gtgtattttc
    41341 gtaggcaaca gctggagtag taaaatctac ccagacatcc gcttcaaaac cagctaaatc
    41401 agccttatcc ttgaaaacag gaataccctg ccattctgac tcagactcaa aaggatccaa
    41461 aactgccacc aagtccaagt ctggatcagt caataccatc tgacaagcag cctggcccat
    41521 ctttccctta aaaccggcaa taattacccg aatactcatc tctactcctg tctaagatac
    41581 aaagtccgta agaacacaaa gtgaaaatag gaattccaat caagaagtgt ctacttcttg
    41641 gaagaactat ctttttcaca cagggttcca ggcgtgttca attatcaaga tacaaaggac
    41701 cttagctgcc cctgaaaaat agggaatggc actgactttc cacgaaaggc aagacaggca
    41761 tcttttttca agaggcaggt agtccgtgtt caatttctaa gattaactag cctagaagtg
    41821 ccaactaaat cactggaata taacctagag caatacttcc tgctcctagg tgcgttccaa
    41881 tgacactacc aaatgtagca agtgaaacat ccgaacccaa gccaaaatca agcaaatgct
    41941 gacgcaattc ttcagccttt tcaggagcat tcccatgaat gacaatgacc cggtattgac
    42001 ctgaagccgt tgtttccttg ataatttcaa ttaagcgttt ggtggccttc ttttcagtac
    42061 gaactttttc gtaaacttca atcacacctt gatcgttaaa ataaaggatt ggcttaatgc
    42121 taagcaaatt gcccaaaatg gcagccccat ttgaaaggcg tccacctttt accaaatgat
    42181 ccaagtcatc taccatgata aaggctgacg tacggctgat ttgaatggct agcttatcct
    42241 gaatgctggc aaaatcatcg ccctgatcac gccaattaaa gacgctttca accatgatgc
    42301 ctaggggagc acttgtaatc aaagtgtctg ggaaagcaat ggttaagccc tcatagtcat
    42361 cgaccatata ctggatattt tggtaaaaac ctgaaattcc agaagatagg aaaagcccca
    42421 aggcatgtgt atagccttgt tctttgagcg aagttaagat ttcatctaac ttggcaatac
    42481 ttggttgact ggtcttaggc aattcagaag cctgagccat tttttggtaa aattcctcag
    42541 cagacagatt gatgccttcg acatattcct caccatcaat attgacagga atatccaaga
    42601 caaacaagtc ttctctttgc aaggtctctt cactgagata agcagaggaa tctgtgaaaa
    42661 cagctaattt catattagaa ctccaaatta attcctggta agtctaatgc aatttcagtc
    42721 acttcgtaag tcaaacgatt gagcatgttc aaacatggac gagccaaggt ttccacctct
    42781 tcttggttca attcacttgg ttcattgaca atacggccat cgatatggtt tacttgtgag
    42841 attgttccac taatgacaaa cttatcaaat acaatcataa agctcaagat gacaatcaag
    42901 gaagtcactt gattttcttg gtcatgttgg agcaattgga aattcacatc caccttggtt
    42961 tcaggagctc cattttcatt ttcccattca aaattacgcg catcaaaatg atactgacta
    43021 acaaattctt gttcacgttt aagattcatg tctttctcca tcggctacaa tattataagc
    43081 tattgtacca taatttttta ttttcatcta gttttctagg atttagtcaa tcccaatttc
    43141 agcacgaact acatctgtga tggtatcaac atagtagtct acttcttctg ttgtaggcgc
    43201 ttctgccata acacgcaaga ggggttctgt tccacttgga cgaacaagga tacggccgtt
    43261 ccccgccatt tcttcttcca tcttctcgat gatggccttg atagctggca cttccatggc
    43321 cttttccttc atgacgtttt ccactcggat attaactaat ttttgtggat aaatcgttac
    43381 ttctgccgcc aactctgata agctcttacc agtttccttc atgattttag tcaattgaac
    43441 tgctgataat tgaccatcac ctgtggtatt gtaatccatc aagataacgt gaccagactg
    43501 ttcaccacca aggttgtaac ctgattttct catttcttca acaacgtagc ggtcaccaac
    43561 tgcagtaact gccttgttaa taccttcgcg attcaaggcc ttgtggaaac caaggttaga
    43621 cataacagtt gtcacaattg tattttgagc caattgtcct ttttcagaaa ggtattttcc
    43681 gatgatgtac ataatcttgt caccatcgac gatgtcacca ttctcatcaa cagcaatcaa
    43741 gcggtcactg tctccatcaa aggccaaacc aatagctgac ccactttctt tgaccacttc
    43801 ttgaagggct tctggatgtg ttgaaccaac attaaggttg atgttaagac cgtctggtgt
    43861 ttccccgata accgtcaatt gggcaccaag gtctgcaaag atttgacggg cactggtaga
    43921 agctgctcca ttagctgtat ccaaggcaac cttcattcca tcaagaggag ttccagttga
    43981 aacaaggtat ccttcatact tacgcaagcc ttctggataa tctaccaaaa ttcctaagcc
    44041 ttctgcactt ggacgaggaa gagtgtcttc ctcagcatct agcaaggctt caatttctgc
    44101 ttctttttca tcatctagtt tgaagccatc accgccaaag aacttgattc cgttatcaag
    44161 agctggattg tggctagcag aaatcatgac accggcactt gctccttcag tttcaaccaa
    44221 gtaagctact gctggtgttg caaggacacc aagtttgtat acgtgaatcc ctactgaaag
    44281 gagacctgcc accaaggccg attccagcat ttcccctgaa atacgtgtgt cacgtcctac
    44341 aaagactttc ggcgcttccg tttcatgttg actaagaaca tagcctccaa aacgtcctag
    44401 tttaaaggct aattctggtg ttagttctag gttagcttct ccacggactc catcagtccc
    44461 aaaatattta cccattgtta taaaatcctt ttctattttt aattcgtttt tgaactagtt
    44521 gctttcgttg acgaagatgt ctccgatgaa ctgcttgtac ttgaatttga tgtgcttgaa
    44581 cttggtgcta ctggttttgt agtcaccttc attattgtat caaacggagt gataactgcc
    44641 ggtaagacaa caccattgcg gtcgattgcc tgcaaaggta ctgaaccact gtaattacct
    44701 gttatgcgtt cgctagttgg caagacagcg ataatcttat caattctatc caatgtctct
    44761 tggtcactcg taatagacgc ttctttatct gacaccatga cattttcaat ttgtacccga
    44821 ctatcaattt gactagggtc aatctctggt acaatcttta ccttatcctt ctgagccttc
    44881 ttaccaatct tgactgtaat tttttgcgga gtcgccacag cggtcagccc attgggtaaa
    44941 tcttcaatgc tcaaaggaac ttcaattgtt ccaacaccgg catctgttag gtcagcagta
    45001 accttgaatt tacgtgtact ttcttgcatt tcactagcta gcgataggcg atttgcacca
    45061 gtcaagacca ctgatacttc tgaagcaaaa ccgctaataa aatacttatc actattatag
    45121 cgtatgtcaa tagggacatt tgttactgta ttagtatagg tttccgtttt tacctgccta
    45181 gcactggtac tgttttgaaa attcgtcgcc gtagcataga caaataagac acaagcaaaa
    45241 aagagtgagg atatgatata taaactattt tttttcatgt ttccatcctc ctagcaatcg
    45301 ttctttaaaa ctaagaccca cttcctcttt tggaagtaag atttcacgta attctgtttc
    45361 aaattcatca agtgttaggt tgtgcttaaa ccttccatta taggttatcg aaattcctcc
    45421 cgtttcctct gatacgacaa aagtcaaagc atctgagact tctgataaac cgatagccgc
    45481 ccggtgtctg gtcccaaatt ccttggaaat ccctgtgttt tttgtcaagg gcagataggc
    45541 agacgtcaca gcgatacgtt cttctttgat gatcaccgca ccatcatgta ggggagtgtt
    45601 gggaataaaa atgttaatga gaagttctgc agaaatctta gcatccaagg gaattcctgt
    45661 cgaaatatac tcctgcaagg tacgtacacg ctgaatagca accaaggccc cgattttacg
    45721 aggactcatg tattcaacag acttaacaaa ggcacgaatc atctgttcct cagcactaat
    45781 aggggcattg gaaaaaaaat ctgtagctct tcccaaacgt tccaaaccag tccgaatctc
    45841 tggagagaag ataacaaccg ccgcaataac cccataagta ataatttgat tgattaacca
    45901 agaaatcgta gtcaaaccaa tcatatttgc aaggatttga gctaaaataa acaccaaaac
    45961 tccacgtacc aaaatcataa tcttggttcc tgcaatagct tttgtaaaat ggtataaaat
    46021 ataagcaaca atcaaaatat caatcagatt gatagctatc gtccatggac ttgcaaacaa
    46081 actggtccaa tattgcagat tggataattg ttgaaaattc atccctgata tcctccctat
    46141 caaaacactt tcgtcctatt ataccatttt ctggcatttt tttccctatc ctagtccatt
    46201 ttacattgaa caaaaatatg ataaaataaa ctgactagaa aaaacaaagg agaaactatg
    46261 tctcaactct atgatattac cattgtgggt ggtggtcctg tcgggctttt tgcagccttt
    46321 tatgcccacc tacgccaagc caaggttcaa atcatcgact ctcttcccca gctaggtgga
    46381 caacctgcta ttctctaccc tgaaaaggaa atcctagacg taccaggctt cccaaacctg
    46441 actggagaag agttgactaa ccgcttgatt gaacagctaa atggatttga tacccctatt
    46501 catctcaatg aaacggttct tgagattgac aaacaagaag aagaatttgc catcacaact
    46561 tctaaaggaa gtcacctgac taaaacagtc atcatcgcta tgggtggcgg tgccttcaaa
    46621 ccacgtccgc tggaacttga aggtgttgag ggctatgaaa atatccacta ccacgtttct
    46681 aacattcagc aatacgctgg taagaaagtg acgattcttg gtgggggaga ttcggctgtg
    46741 gattgggctt tggcttttga aaaaatcgca ccaactaccc ttgttcaccg cagagataat
    46801 ttccgtgcct tggaacacag tgttcaagcc ttgcaagaat catctgtaac catcaagaca
    46861 ccattcgccc ctagccaact ccttggaaat gaaaaaacac ttgataaact tgaaatcaca
    46921 aaagtcaaat ctgatgaaac tgaaaccatt gacctagacc acctctttgt caactatggt
    46981 ttcaaatctt ctgtcggtaa ccttaaaaac tgggggctcg acctcaaccg tcacaagatt
    47041 atcgtcaaca gcaaacagga atccagccaa gcaggtatct atgctatcgg tgactgctgc
    47101 tactatgacg gaaaaattga tctgattgcg acaggcctcg gagaagctcc aactgctgtc
    47161 aacaacgcta tcaactacat tgaccctgaa caaaaagtac aaccaaaaca ctctactagt
    47221 ttataaaaaa aaccacgagt cacataggat tcgtggtttt ataattcatc cgctatctta
    47281 ttgatttttc tgagtctgtg attgacacca cttttggtca gaggggtgct gagactatct
    47341 gctaactgct ggatagagta gtctgggtgc tgaatcctca gttgcgccac ttcctgcaaa
    47401 tctactggca aattttctaa gcccatgata tctttgattt tactgatatt gttaatggtc
    47461 ttcatgctgg cagaaactgt ccgagcgata ttagctgtct cggcattatt agcccgattg
    47521 aggtcgttac gggtttctcg caaaatctta acccgctcaa aatcatcacg tgcctgcatg
    47581 gctccgatta ctatcaagaa gtccataatg tcttctgctc gctggagata ggtcacagcc
    47641 cccttcttgc gctcaagcac cttggcatcc agtaaaaact gttggagaag ggaggcaatt
    47701 ccttgcgcgt ggtccagata aacagaactg atttccaact ggtacttgcc tgactcaggg
    47761 tcacgaatgc tcccatttgc caagaaagcg ccacagagat aggcacgacc tgcttcctca
    47821 tccgataaaa tcgcctcatc aatacctgtt tccaggccaa agaaagagtc tgccaagtgc
    47881 aaatcactta acaaatcctg caccttttca tctgtaaaaa cggtatagac gcgattcttg
    47941 cgaagattgc tccgttggtg gtgacgaatt tcagatttga tttcatagaa atggagaaag
    48001 gactcataga ggtgacgggc cagtttggca ttttctgtca caactgacaa agtcaagccc
    48061 gaagtcgaga gaccgatgct accagacatt ttgataatgg cagataattc atgccagctc
    48121 agatggtgtt ggcccaggat ttcttctttt actgctactg tgaaactcat tttttcacct
    48181 gtataatgcg catcaactcg tccacaatca aatctccatc gtggaaggca ccgccatttt
    48241 ccagacgaag gaagttagat gaaatcacgc gcgaaacttg cttacaaaga cctacaaaat
    48301 cgtgttccac ttgcactaag tattcatcaa aacggttgga attcatgtat tcctgaggca
    48361 ctttttcaat attcaccaag acagtgtcga taaaagggcg accaaggtga cgatgcaaga
    48421 cttccacgtg gtcgctatct gtaaagtgtt ccgtctcccc acgttgggtc atgatattgc
    48481 agacataggc aatttctgcc ttggtttcca aaagagcccg cccaatttcc ttaatcacga
    48541 tattgggcaa aatagaggta aagagggaac ctggccctag gacaatcatg tcactttcaa
    48601 ggatggtctg cactactcga cggctggcca gaggcgtatc atcgtttagg gcattggtca
    48661 catagacatt gtcaattatg cctcgatggt ctacaatatg actctctcca gccacttctg
    48721 tcccatcctg aaagactgca tgaagggtca aaggatggtc actggaagga taaattttcc
    48781 ctgttgtatg gaaaaatttg ctcaataact gcatggcatt ataggttgaa ccctgcattt
    48841 ctgacaagcc agcaatgatg agatttccca atggatggcc agcaaaggct ccggcatcct
    48901 cagagaaccg atactgaaag accttctcat aaaacttagg catatccgac atggccacaa
    48961 ggacattacg aagatcacct ggcggtgtca actgttgcat attttttcgg agttcacctg
    49021 aagaaccacc atcatctgcc accgtcacga tagctgcgat ttccacatct ttttcccgca
    49081 gactttttag aatgacggga attccagtcc ctccaccaat caccgttatc tttggttttc
    49141 tcatgaacgg tttaccgttt cctttctgcg gtctttgtcg cgatgccctt cattaacaga
    49201 ccaattcttg gataagtcct gcgccaagcg tttagcaaat gccacactac ggtgttgtcc
    49261 acccgtacat cccatggcaa tggtcaaaac ggacttacct tccttttggt aacttggcag
    49321 aatcggctca atcaaggcca ataaatgttg ataaaagtct tctgactcag gatggttcat
    49381 gacataatca taaacaggtt catccacacc cgtttggttt ctcagttctg gtagataata
    49441 gggatttggc aagaaacgga catcaaagac caagtccgca tcaatcggga ttccatactt
    49501 aaatccgaaa gacatgactt cgatacggaa agactgggct tgttcttggt ctgaaaactg
    49561 ctctgcaagg gttttgcgca gctcacgtgg agtgagttca gtcgtatcca ccacattttg
    49621 gctcatattt ttcaaaggtg ccaagagttc acgttccaac ttgattccat ctaaaatacg
    49681 accgtctgct gctagtgggt gactccgtct ggtctccttg taacgagcga ccaattcctt
    49741 atcagccgca tccaaaaaga ggattttgaa atccaaacca tcttgatttt ccaactcatc
    49801 caaaacagct tgaatctctg aaaagaaaga acggctacgc atatccacta ccaaggccaa
    49861 cttaggattg tcttccttaa tttcaaccag ctgcaaaaac ttaggcaaga gagctggcgg
    49921 catattatca atggtgaaat aacctagatc ctcgaaggac tgaatggcta cagttttccc
    49981 tgcgccactc atccctgtca caatcaccaa gtgaagttgt ttctttgtca tctttttctc
    50041 cttatatcaa aagaagtttg gcaacaccaa acttcaacta gcttatccaa tctctgcgat
    50101 gacttcaatt tcgactttta catcacgagg aagacgagct acctccacag ctgaacgagc
    50161 tgggaattcc tctttgaagg ccgtttggta aacctcatta aaaggaacaa agtcgttcat
    50221 atcgctcaag aagcaagttg ttttgacaac atggtcaaag tctgttcctg cttctgccaa
    50281 aatagcaccg atgtttttca agacttgctc tgtctgttct tggatattct ctcctacaat
    50341 ttccccagtt tcaggggata ggggaacttg accgctagca aacaaaaggt tgccaacgat
    50401 ttttccttga acatagggtc cgatagcctt tggggcctta tctgtatgaa ttgtttttgc
    50461 cattttcttt tcctcacaat ttttctaaga ttgcatccca agcctcatcc atccctgcct
    50521 tgctgacaga tgaaaagagg atgaaatcgt cacttgggtc aaagtttaat ttctttttga
    50581 ttgctgattc atgcttgttc catttaccac gaggaatctt gtccgccttg gtcgccacaa
    50641 tgatgactgg aatctcataa tacttgagaa attcgtacat ctgcacatca tctgctgacg
    50701 ggtcatgacg aaggtcaact agactgacaa ccgcacggag attttcccga gtcgttaagt
    50761 actcctcaat catgcacccc cacttttcac gttccttttt agaaacacga gcatagccat
    50821 aaccaggcac atccacaaag cgcatcttgt catcaatgtt aaaaaagttc aggagctggg
    50881 ttttaccagg ttttcctgat gtacgggcga gattcttacg gttcaacata gtgttgataa
    50941 agctggattt accaacattt gaacgccctg ctagggcaat ctctggcagt tcatcctgcg
    51001 gatagtggga cttattagct gcactgagca agatttcagc attgtgtgta ttaagttcca
    51061 tagtcacctc taggctgttt ctaggatcgg tttatccgtt ccatctacag tttctttagt
    51121 gatgcgaacc aatttcacat tttcctgact cggcacctca aacatgacat ctagcatggt
    51181 ttcttcgatg atggagcgaa gtccacgcgc ccctgtcttc cgttcgattg ctttattagc
    51241 aatctcttga agggcttcgt cgtcaaattc caactcaaca tcatcataag aaagcaaggt
    51301 ttggtattgt ttcaccaagg catttcttgg ctctttcaag atgcgaacca agtcatcaac
    51361 ggtcaattgc tcaagagccg caaaaacagg caagcgtcca atcaactcag ggataatacc
    51421 aaatttttga atgtcttcag cgatgatttc ttgcatgtat gagctgtttt cgtcaatcgc
    51481 cttattgttt tgaccaaatc cgataacttt ttcacccaga cgttgtttga caatttcttc
    51541 aataccatca aaagcaccac ccacgatgaa gaggatattt tttgtatcca cttgaatcat
    51601 ctcttgttgt ggatgtttgc gtccaccttg aggcggcacg ctagcaacag ttccctcaat
    51661 aatcttgaga agggcttgtt gcaccccttc accagaaaca tcacgtgtga tagacacatt
    51721 ctcactcttc ttggcaatct tgtcaatttc atccacatag ataatgccac gctctgcacg
    51781 ttcgatgtta aagtcagcaa cctgcaagag tttgaggagg atattttcca cgtcctcacc
    51841 cacataacca gcctccgtca gagctgtcgc atccgcaata gcaaaaggta cattcaagct
    51901 cttagccaag gtctgggcaa ggaaagtttt ccctgaacca gttgggccaa tcatcaaaat
    51961 gtttgacttc tgcaaatcta catcttctga ctcttcgcgt gtatcgtgga aattgatgcg
    52021 tttgtagtgg ttataaaccg ccactgccaa ggcacgcttg gcacgatctt gaccaattac
    52081 atagtggttc aagatatgga ggagttcaat tggttttggc acctcagaca agtctgccaa
    52141 gacttcctca accaattctt ctcgaatgat ttcctgagct aactccacgc attcattaca
    52201 aataaaagca ttgttgccag caattatttt ttgtacttct tcttggtttt tgccacaaaa
    52261 tgagcaataa accatcatat cattttttct atttgtagac atgatttcct tccattctat
    52321 actgtcattc tatctaaaat aaggtcatgt aaaaagcatg aatactattg accagattgg
    52381 taaaggcatt taaccaaagg aggatagaaa gcccgtaacg ctttttacga aaagcctgtg
    52441 ctcctgccag aaagcagatg aaacacagaa aagccgtgaa tagaccaaat aaactccgtt
    52501 ccattagact tcctttctct tgcggtattg gatggtaaaa tcataaggat tcttctcatc
    52561 tttggcgtaa aatttgcttg aaactgtctc aaaaagagac aagtcaagct cttcagggaa
    52621 ataggtatct ccttccaccc gagcatgaat gtgagtgaca atcacttcat caaggtaagg
    52681 tccaaaagcc tgaaaaattt gcttcccacc gataatgtag agattctttt cttgagcctg
    52741 ataccagtca agaacagact ggacgtcctg aaaagtagca accccatcta tcttttcttc
    52801 cggattacgc gtcaaaatca aggtttcccg ttttggaagc aagcgacgtc ccatcccatc
    52861 aaaggtcaca cgccccatca agatagcatg attcagagtt gtttctttaa agtgctgcaa
    52921 ttctgctggc aaatgccaag gcagacgatt ttccttacca atcacaccct cttcatcctg
    52981 ggcccaaata gctacgattt tcttagtcat gcttccatcc ttttcactga tagtactatt
    53041 ttatcaaaaa actcaaaaaa agactggttt ggaatagctt acaaaataga aaaaatctgt
    53101 aagaaatttc ctacagattt atctatgttt ccttatttct tacaaaccag gtgcttgtcc
    53161 aagttcggct gcaagcatcc aaattgtttt atctgtttca gttttagcgc ctgcaaagat
    53221 accgtttgtc acatcgtcac cttcttcatc agtgacatcc aaaccttttt ggaaaagttc
    53281 tgacaagtaa cggtagataa caagaacacg ttccaagctt tcttcaacat tacggtattc
    53341 accagcttct tcttcgattt cactattttg aaggaactct gtcaatgtag agaatgggct
    53401 tccaccgagt gtaatcaagc gttcgctgat ttcatccaat tgaccgtcaa gagcttccat
    53461 gtactcatcc atttttggat gccatacaag gaaaccacga ccatgcatat accagtgcac
    53521 ttggtgcaaa gcaacgtgag ctacatacaa atcagcaaca gcttggttca agacttcctt
    53581 tgtttttgcc aatgctactg gcgctgcttt tgtcaatgat gttacgtctt ttactgcttc
    53641 ttttttcaat tctaccattt tctttacctc attcattatt ttttgtaacc acttcttaat
    53701 gattactacc ttagtatact actaaggaaa accaatagca agacaaagaa cttatatgag
    53761 aaaagttgca atagactgat aatttaagaa ttctttagaa gacaaaaaag agggttggat
    53821 gcttatagtc aatggaaatc catcagcaaa ctaggaaact aaacccagct tgaccaaagc
    53881 acaagttttg aggtcgcagg tagaactgac caagctgatg tggtttgaag aaattcccca
    53941 atactataat agattgaaat aagatgaaac caagtcgatt aggaaaggta aatgaatttc
    54001 taaaatgttt taccaatcac aaggtctttg tctatattca atctactata taagcttcat
    54061 ttccgagcaa gatcttgaat ttactcgagg atgaactatc ataaaacaaa gaaaaagagg
    54121 gtgctactat cacatccctc tttcaaatca tcgcttaata ccaaacgctg acatctacgc
    54181 gcccttggat tcctttcatg tattcagaag aggtatattg ccaacctttt tctcctgaat
    54241 aataagggtt ttcccattct aaagcattcg tataggccgc tacccagttt acatgtttta
    54301 aaatatctgg gtgttttaaa cgcgtctgta ataaactacg atagctatag acatacacat
    54361 tttgataacc cgcctgcttc atcgtgtcca tgtacttgtt gatgatttta acccaagtgt
    54421 ttgtatcact tggagctctc ttgctcttat ttacatattc ccagttctca acatcataat
    54481 agatagggta agacaggttc atattgtatt tctttataag ttcaatggtc tgtttagcgt
    54541 cattctcagc atcggtctca ttttcagcat aggtatagag atagacacca taaggaattc
    54601 ccagacggtt taactcctta atgttatgcg ccaattcctt gtcttcttta ccgctataac
    54661 ctagacgaac aatgacacca tccacctcgt tctcatcaat aacctttttc caatcattga
    54721 tacgaccatt gtgctcacta atatcaatga ttttcttagc atgttcggtt cccacttgtt
    54781 cttctctatt attaaagaaa tagcgtttac catctctgtg aacccagccg acattcaaat
    54841 ctttcttttc tttgagctca ccagaggccg caaagatata gcgagcacca tccataatca
    54901 cttcgtcagt cgccatggca ccacttccag tcaaatagta gttgccttgc cactcattcc
    54961 gagccatata gccccacttc ttgaaatagt accatttgcc gcccactttt tgccactctt
    55021 ggttagcata agttccatcg gattttagat aaaaataagc agaataagct ggatcataga
    55081 gccattcatt ttgcatcata gctccttgac cattcaagaa ataacttcct tgccattggc
    55141 ttttagccat gtaaccccac ttcttgaagt agtaccactt atttccaatc aattgccatt
    55201 cttgatgagc ataagcccca tctgacttga gataaaacca actcttgtaa ttactgtcat
    55261 agatccactc gttttgggcc atatatccac ctgatttcag gtagtaattt ccatgccatt
    55321 cattctgcga gtaacgacca tctgaattaa tataaaacca agccttatag tagttgtcaa
    55381 aaatccattc actttgagct ttagaaccat catcctttac ataataatcc ccatcccagt
    55441 gggcagcagc attagtctgt acttctgcgc tcgtttgcgt tttattagaa gactgatttt
    55501 gctctgaact acttgaagct gtcgttgtat cctgcgaagt ttttgctact tcagtttcat
    55561 ttgcagcgac atgactagtt gccaagccta gtaaacagat acttgctaat ccaatttttg
    55621 ttttcaatct ttctctccta taaaaaatgt aacagacatc tgaatgctgt tccacctagc
    55681 ttttgctact tactgattat tttacaaagt caagcaaagc caagaagctt tcagcttcaa
    55741 gtgacgcacc acctacaagg gcaccgtcaa cgtctgggca agccatgtat gaagcaacat
    55801 tttcaggttt aacagaacca ccgtattgaa cacgaacttt gtctgcgact tcttgaccaa
    55861 agtcagcagc tacaacgtca cgaacaactt tacacatttt ttgtgcatcg tcttgtgaag
    55921 ctgatttacc agtaccgata gcccagattg gctcataagc gataactgag gcagcaactt
    55981 gttcagcagt caatccagcc aatgcagcag atacttgagc acctacgaat tcagcagctt
    56041 taccagcttc gtaagtttca agtgattcac cacaacagat gattggaagc ataccgttcg
    56101 caaagattgc ttttgctttt ttgttgatat cttcgtcagt ttcatggaag tagtcacggc
    56161 gttctgagtg accgataaca acgtaatcag taccgatttc tttcaaaact tgtgggctag
    56221 tttcaccagt gaaagcacct gcattttcaa agtagcagtt ttgagcagca actttaaggt
    56281 ttgagccttt tgcaacagca agaacagttg tcaaatcaag agctggagca gcgatacctg
    56341 cttcaacaag atctgatgaa ggaagttttg atgcaactgc ttcaacgaat gctttagctt
    56401 cttctggatt tttgttcatt ttccagttac cagcgataaa tggtttacgt gacatttcac
    56461 atacctcttt tttcaattta ttttctattt attctatcac aattatacac agcttgcaaa
    56521 tcttactcgg atttcaagcc tacttgcatg gattaatcct tccagagatc catggcattt
    56581 ctgaaatctg cagatacctg tgtcaactga ggattgcttg cttctctttc tgctctcttg
    56641 gcctcaattt gagccacact cttgattcct tcatggcgcc agtttctcaa aattgcctga
    56701 atgtacttcc agtttggttt tccattcaaa acagcttcac gaagagcctc cttaatcaag
    56761 tcagcactgg ttccatcttc ctttagtgtc ttggtcaaat cctcaatctc aaaaggcgtc
    56821 aacaatcgtc ccaactcctg ctggaaggtt tccaccaaat ccttgagctg gttttgaggt
    56881 gttagctggt ctgaacttga acgaactgct ccaaacaggt catccaaacg ttccaaggcc
    56941 aaactagcat caaagaacaa ttcaatttcg ccatttaatt cgatagtacg atactggagc
    57001 agtccccttt ccgtcagatt agaaatggac tggttgacat ccgaaatttc cttgccaatc
    57061 ctttcagcaa tctggcttgg cgacatttct tctaagcctg tcgtattttg caaatagaaa
    57121 aattgccaaa ccagaaaatc gtcgctagaa ggaaagagtt ccttaaaatg caagagcagg
    57181 gcactcggta aaaccaaggt acctgattta aaagcgtcta aatatgtcat aattcctctt
    57241 ataaataccc atatgcagat gcatcatctt ctatctttct ccaatcaaaa ggcgtctcct
    57301 gatagaccgc atggtttacc caattactga aaaagagggc tgcagatgaa gaccaacaaa
    57361 gacaaggtac ctgattaaca tcatcatctt taaagtaatt ttctggaata tgtgggtcga
    57421 aacctgcatc acgatctcga aaatactctt ttgccaaggt atcacggtca tactccaaat
    57481 gaccaaaact ataaatttct cgtaaatcac gactggccaa aatagaaacc ccaacctgag
    57541 gtccttctga taaaatctcg agattggtct tgtttaagac ctcttcctta gaaatctccg
    57601 tgtgccgtga atgaggggat acatagctat catcaaagcc tctaaataga aggtgaccct
    57661 cttttagggt gtcctgagga taaatacctg atagcttact gtccatctgg tatttttcta
    57721 caccatagcg cagataaagc ccagcctgag ccccccaaca gatatgaagg gtcgaataga
    57781 catgagtctt agaccactca agcatctgtc taaattcctc ccaatagtcc acttcctcaa
    57841 atggtaaatg ctcaactgga gcacccgtga tgatcatccc atcaaaatac tcatccttga
    57901 cttcaggaaa agttttatag aaggtctcca tgtgctctga acgagttgtt ttagaacggt
    57961 ggctctccat atagagaaaa tcaatatcca gttgtagggg tgtattagcc aagtggcgca
    58021 acaactgggt ctctgtgacc attttctgtg gcatgagatt taaaattaaa atcttcaaag
    58081 gacggatatc ttggtgggca gcacgttgat catccatgac aaagatattc tctgtccgta
    58141 aaatctcaac agctggcaat tttttatcaa ttcgaatcgg cataaccctc tcctaactgt
    58201 actctttcag gaataattgc atatgtttga agacaaatct caaacactta gtccttttat
    58261 tatactgcaa gaagatatag ttttcaatta tagtttttct ctaactagtt atagtctatt
    58321 tttatatcct agtgtagaga aaacagccct agggactgtt ttcattaata atgcataaga
    58381 actttgtagt cgtagtcacc aattttttca cggccgttca attcatccaa ttcaacaagg
    58441 aaggcacaac ctgccataac accaccaagt ttttcaatca tctcgatagt tgccttaaca
    58501 gttccacctg tcgccaaaag gtcatctaca ataagaacac gttgacctgg cttaatggca
    58561 tccgcgtgca tagtcaaggt atcgacaccg tactcttttt catagtcagc agaaataact
    58621 tcgcgtggca atttacctgg cttacgaaca ggcgcaaaac caattcccaa ctcaaaggca
    58681 actggacaac ccacgataaa tccacgagct tcaggtccca cgatcatgtc gactttcttg
    58741 tcagtagcat actgaacgat ttcacgaaca gcgtagctat aagcatttcc atcagccatc
    58801 aaaggactaa tatcacggaa ggtaatgcct tcctttggat aattttcaat tgttgcaatg
    58861 taatctttta aattcatctt tttctttctt tcaaagtttt ttactctcta ttatagcata
    58921 ttttttaaga aagaaaaaag gaaaagttaa cttcaataat tatctaacgt tttgacgatt
    58981 tataactagc catcgcaata aagcccaatt tctgtttatt cttagcaaac attttataca
    59041 tagttaaaaa ctgctttcta ttctcctttt tacaagcatt tacacaaatt ttcaaagttc
    59101 ctagcaaacc ttcgtcataa atcatacccg ataatttcat taatgtcatt tcaccagtca
    59161 atgctttcac atcacaataa cctgattcta tcatcacctg ttcccaacca tcttgagtta
    59221 aaggacctac atttacatga attgcttgtg ataattcctg tctgatagac tctttagctt
    59281 ccttaagaag cacatcatgt gtcaagagaa gacctccagg ttttaatacc cttagatatt
    59341 ccattacaca ttttttctta gcttgatcgg cttgcatagt cagcatagct tcatttataa
    59401 caatatcaaa actagcatct tgataaggaa gtttcattgc atttgctctt tcaaaactga
    59461 ttaaatgagc aacacctgcc gttccagcaa attttttagc cacttctaaa gcttgagcat
    59521 ccatatcaac agcagttatc ttgcaaccaa aacgctgtgc caactcaatt gctgtagttc
    59581 ccctattaca cgcaacctct agtattctct tttcttttga aaatcctcct tctgcaatta
    59641 accaatctgt ggcacgcttt ccacctggac gtaagcgttt tttccccaat tttgctaaaa
    59701 acttatgacc tgcttctgac atttgaacac ctctgttttt tcttcattat aacacaaaat
    59761 gatattatct gacaattcta atctattatt tgataaacta gaatcaaaag catacaagtc
    59821 accataacta tagcataaat ttattattac ctctctagtt cgaattcaat tgctcacgta
    59881 gtttacgcat atagcttcac ttgtagatgg tacccacaaa taatactcaa tggaaatcaa
    59941 agagcaaact aggaaactag ccgtaagctg ctcaaagtac atctttgagg ttgcagataa
    60001 aactgacgaa atcagtaatc atacgtacgg caaggcgacg ttgacgtggt ttgaagagat
    60061 tttcgaagag tattaaagag catcacaata tagatgcata atatgacttc tctagcaaaa
    60121 aggagagaag cattttgttt ctctccctag attaactgat atctctccac tacaattgat
    60181 aaagagatat cttttcttgt agtgctttga attttattta ttttagtaga ttgttttttc
    60241 agtttctaca tcgaagaagt gtgctttgtt caagtcaaat ccaagctcaa ctgttgcacc
    60301 tgtttgcaag tagtcacgag catcaacttt tgcaacaaac tcgtctttac caacttggca
    60361 gtaaaggtga gattctgaac caagcagttc tgatacagag atagtcgctt ttacaacaca
    60421 gtctgggaat gtttcaagga aagcaggttc tgcattcacg tcttctggac ggataccaaa
    60481 gatcaattct tttccttcgt agcctttttc acgaagaact ttcaatgctc cttctggcac
    60541 tttcaaacgg aaaccgtcag aaacaatttc gctaccaacc aatttcacgg tgatgaagtt
    60601 catagctggg cttccgatga atcctgcaac gaatttgtta actggatttt tgtaaacttc
    60661 ttgaggagta ccgatttgtt ctacacgtcc gatagtacct gtaccagcag ggttcttagt
    60721 agctgacata ataacgatac ggtctgcaag tgtcatcgct tctgtttggt cgtgagttac
    60781 atagatagtt gtagctccga tacgacggtg aattttagcg atttcagcac gcattgatac
    60841 acgaagtttg gcatccaagt ttgacaaagg ttcgtccatc aagaatactt tcgcatcacg
    60901 gacaatcgca cgccccatgg caacacgttg acgttgacca cctgaaaggt cagctggttt
    60961 acgttccaag aattctttca atccaagtat ttcagctgct tcttgaacac gtttgttaat
    61021 gtcttctttg ctgtatttac gcaatttcaa accgaaagcc atgttgtcat aaacagtcat
    61081 gtgtgggtaa agagcgtagt tttggaatac catggcgata tcacggtctt ttggagctac
    61141 gtcgttgaca actacgccat cgatagatgc agtaccttct gtaatgtctt caagaccagc
    61201 aatcatacgg agtgtagttg atttaccaca tcctgaaggt cctacgaaaa cgataaattc
    61261 tttatctttg atgttcaagt tgaaatcttc aactgaatag tgttcgctgt ttggatattt
    61321 tttgtaaata tttttaagat tcaattctac catgaggtga actccttttg tcttttgata
    61381 attatattat atatgaaaac gctttatatt tctatggcaa gatgaccaaa aaaataaaca
    61441 agttctgtgc aacttgcaca aaactttaga gaatatcgga gaatttgaag aagataatct
    61501 ttattattct tctatagaca aaagcagaaa caaggatcag ttttcccata tttt
//
LOCUS       DAVLHB010000008        52116 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLHB010000008 DAVLHB010000000
VERSION     DAVLHB010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.008"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(808..2535)
                     /gene="ezrA"
                     /locus_tag="VXE36_000563"
     CDS             complement(808..2535)
                     /gene="ezrA"
                     /locus_tag="VXE36_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0778919.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2617..4563)
                     /gene="gyrB"
                     /locus_tag="VXE36_000564"
     CDS             complement(2617..4563)
                     /gene="gyrB"
                     /locus_tag="VXE36_000564"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0778920.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4578..5141)
                     /locus_tag="VXE36_000565"
     CDS             complement(4578..5141)
                     /locus_tag="VXE36_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0778921.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5226..5780)
                     /locus_tag="VXE36_000566"
     CDS             complement(5226..5780)
                     /locus_tag="VXE36_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0778922.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5791..7014)
                     /locus_tag="VXE36_000567"
     CDS             complement(5791..7014)
                     /locus_tag="VXE36_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0778923.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7051..9501)
                     /locus_tag="VXE36_000568"
     CDS             complement(7051..9501)
                     /locus_tag="VXE36_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0778924.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9701..10630)
                     /locus_tag="VXE36_000569"
     CDS             complement(9701..10630)
                     /locus_tag="VXE36_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0778925.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVHKLHPKNRFLDTGFYDYDPDMVR"
     gene            10770..11057
                     /locus_tag="VXE36_000570"
     CDS             10770..11057
                     /locus_tag="VXE36_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0778926.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11091..12425)
                     /gene="ciaH"
                     /locus_tag="VXE36_000571"
     CDS             complement(11091..12425)
                     /gene="ciaH"
                     /locus_tag="VXE36_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0778927.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12415..13089)
                     /gene="ciaR"
                     /locus_tag="VXE36_000572"
     CDS             complement(12415..13089)
                     /gene="ciaR"
                     /locus_tag="VXE36_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0778928.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13198..15744)
                     /locus_tag="VXE36_000573"
     CDS             complement(13198..15744)
                     /locus_tag="VXE36_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0778929.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15867..16307)
                     /locus_tag="VXE36_000574"
     CDS             complement(15867..16307)
                     /locus_tag="VXE36_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0778930.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCVVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16282..17151)
                     /locus_tag="VXE36_000575"
     CDS             complement(16282..17151)
                     /locus_tag="VXE36_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0778931.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAESHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGVKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17193..17921)
                     /locus_tag="VXE36_000576"
     CDS             complement(17193..17921)
                     /locus_tag="VXE36_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778932.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17929..18408)
                     /locus_tag="VXE36_000577"
     CDS             complement(17929..18408)
                     /locus_tag="VXE36_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0778933.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18419..19117)
                     /locus_tag="VXE36_000578"
     CDS             complement(18419..19117)
                     /locus_tag="VXE36_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0778934.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(19110..19346)
                     /locus_tag="VXE36_000579"
     CDS             complement(19110..19346)
                     /locus_tag="VXE36_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0778935.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19446..20372)
                     /locus_tag="VXE36_000580"
     CDS             complement(19446..20372)
                     /locus_tag="VXE36_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0778936.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20447..21262)
                     /locus_tag="VXE36_000581"
     CDS             complement(20447..21262)
                     /locus_tag="VXE36_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778937.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21266..21586)
                     /locus_tag="VXE36_000582"
     CDS             complement(21266..21586)
                     /locus_tag="VXE36_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0778938.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21838..21918)
                     /locus_tag="VXE36_000583"
                     /pseudo
     CDS             complement(21838..21918)
                     /locus_tag="VXE36_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21962..23959)
                     /gene="metG"
                     /locus_tag="VXE36_000584"
     CDS             complement(21962..23959)
                     /gene="metG"
                     /locus_tag="VXE36_000584"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0778939.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPEGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(24083..25342)
                     /locus_tag="VXE36_000585"
     CDS             complement(24083..25342)
                     /locus_tag="VXE36_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778940.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25344..26045)
                     /locus_tag="VXE36_000586"
     CDS             complement(25344..26045)
                     /locus_tag="VXE36_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778941.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(26029..27228)
                     /locus_tag="VXE36_000587"
     CDS             complement(26029..27228)
                     /locus_tag="VXE36_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0778942.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKISEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KTDEATN"
     gene            27514..28860
                     /gene="gor"
                     /locus_tag="VXE36_000588"
     CDS             27514..28860
                     /gene="gor"
                     /locus_tag="VXE36_000588"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0778943.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            29057..29593
                     /locus_tag="VXE36_000589"
     CDS             29057..29593
                     /locus_tag="VXE36_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0778944.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            29644..29730
                     /locus_tag="VXE36_000590"
                     /pseudo
     CDS             29644..29730
                     /locus_tag="VXE36_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29799..30014)
                     /locus_tag="VXE36_000591"
     CDS             complement(29799..30014)
                     /locus_tag="VXE36_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0778945.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            30112..30432
                     /locus_tag="VXE36_000592"
     CDS             30112..30432
                     /locus_tag="VXE36_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778946.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30462..30800)
                     /locus_tag="VXE36_000593"
     CDS             complement(30462..30800)
                     /locus_tag="VXE36_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778947.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30812..31531)
                     /gene="trmD"
                     /locus_tag="VXE36_000594"
     CDS             complement(30812..31531)
                     /gene="trmD"
                     /locus_tag="VXE36_000594"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0778948.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31521..32039)
                     /gene="rimM"
                     /locus_tag="VXE36_000595"
     CDS             complement(31521..32039)
                     /gene="rimM"
                     /locus_tag="VXE36_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0778949.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDYED"
     gene            complement(32070..32858)
                     /locus_tag="VXE36_000596"
     CDS             complement(32070..32858)
                     /locus_tag="VXE36_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0778950.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(33435..33674)
                     /locus_tag="VXE36_000597"
     CDS             complement(33435..33674)
                     /locus_tag="VXE36_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0778951.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33694..33966)
                     /gene="rpsP"
                     /locus_tag="VXE36_000598"
     CDS             complement(33694..33966)
                     /gene="rpsP"
                     /locus_tag="VXE36_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0778952.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            34145..34345
                     /locus_tag="VXE36_000599"
     CDS             34145..34345
                     /locus_tag="VXE36_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778953.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMNLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            34824..35045
                     /locus_tag="VXE36_000600"
     CDS             34824..35045
                     /locus_tag="VXE36_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778954.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEKVEDFQDDDEIPTII"
     gene            35129..35932
                     /locus_tag="VXE36_000601"
     CDS             35129..35932
                     /locus_tag="VXE36_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0778955.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(35988..37529)
                     /locus_tag="VXE36_000602"
     CDS             complement(35988..37529)
                     /locus_tag="VXE36_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0778956.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(37531..38013)
                     /locus_tag="VXE36_000603"
     CDS             complement(37531..38013)
                     /locus_tag="VXE36_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0778957.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(38013..39098)
                     /gene="rlmN"
                     /locus_tag="VXE36_000604"
     CDS             complement(38013..39098)
                     /gene="rlmN"
                     /locus_tag="VXE36_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0778958.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQINLAVS
                     LHALNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLRFNTMKRDRQKAVAAVNP"
     gene            complement(39119..39649)
                     /locus_tag="VXE36_000605"
     CDS             complement(39119..39649)
                     /locus_tag="VXE36_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0778959.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(39806..40411)
                     /locus_tag="VXE36_000606"
     CDS             complement(39806..40411)
                     /locus_tag="VXE36_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0778960.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(40552..41589)
                     /locus_tag="VXE36_000607"
     CDS             complement(40552..41589)
                     /locus_tag="VXE36_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0778961.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(41623..42558)
                     /locus_tag="VXE36_000608"
     CDS             complement(41623..42558)
                     /locus_tag="VXE36_000608"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0778962.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(43111..44301)
                     /locus_tag="VXE36_000609"
     CDS             complement(43111..44301)
                     /locus_tag="VXE36_000609"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0778963.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(44516..45859)
                     /locus_tag="VXE36_000610"
     CDS             complement(44516..45859)
                     /locus_tag="VXE36_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0778964.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45999..46814)
                     /locus_tag="VXE36_000611"
     CDS             complement(45999..46814)
                     /locus_tag="VXE36_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0778965.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNNLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            complement(46866..49046)
                     /locus_tag="VXE36_000612"
     CDS             complement(46866..49046)
                     /locus_tag="VXE36_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0778966.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGIIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(49332..50258)
                     /locus_tag="VXE36_000613"
     CDS             complement(49332..50258)
                     /locus_tag="VXE36_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0778967.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(50251..50943)
                     /gene="ftsE"
                     /locus_tag="VXE36_000614"
     CDS             complement(50251..50943)
                     /gene="ftsE"
                     /locus_tag="VXE36_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0778968.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKKRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(50961..52056)
                     /gene="prfB"
                     /locus_tag="VXE36_000615"
     CDS             complement(join(50961..51983,51985..52056))
                     /gene="prfB"
                     /locus_tag="VXE36_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0778969.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
BASE COUNT        15465 a        11389 c         9329 g        15933 t
ORIGIN      
        1 tttcgccaaa tcattgtttg attacagtct aaaagttcta taatctcttt ataagatttg
       61 cccatcagac gaaatataat aaattgaaac tagaatagta cacctctact tctaaaacat
      121 tgttagaaat caatttgact gtcctaatcg atttgtactg ttcttatttc attttactat
      181 agaacgattt gaaggtgttt atgatattta gctgtacgag agtcttttaa aagtgttttg
      241 atggtttgga tttcttcttt agttgatttc atattactat tatatggtgc ttttttattt
      301 tagtctggta taaatagcga gaaatatcta tcctatcttc tagaatgtct tccaaacgag
      361 aaaactctcg taaacaaaga ggttttagag gcctatttac cgtagactaa agttgtacaa
      421 gaaaagtgca aataagaaat ctccagatta ggaactatcc gtgagttctc tagtctggag
      481 atttttcaat agacttcatt attggacggt taccaagtta ctcaaagtac agatttgaag
      541 ctgcagataa gactgacgaa atcactttaa tactaaatga aaatcaaaaa gcaaactaag
      601 aagctagcct caggctgtac ttgagtacgg taaggcgacg ctgacgtgat ttgaagagat
      661 tttcgaagag tataaaacac tgttttgagg tggtggataa atcggctggg caaaaactca
      721 atctcaggag aaaatgaagt aaatctcccc acaactatag aaaaagattt gattctgctc
      781 ctcacacaat aaaatctttt tcttttatta aaaacgaatc gtttcacgtg ttttctcata
      841 tgaggtaaca aagcgattgg ttacaccagg ctctgccact tccaatgctt gagaaatctt
      901 gtcaaatgaa gcgtgataat caaattcttt ttcaaaaata tctaaagctt cgttaaatgc
      961 ttcttgaatg cgttcatcaa atgagcgata gcggttagaa tattgcaaga gttgctctgt
     1021 caaagttgca tattgtacaa tattataagt ttccgtttct aaagcttcca tatcattcgt
     1081 tgcaatttca agaactcggg taacagattc aatgttaatc attttttgtt ctaactcaac
     1141 cattaaatcc tcggtattat tgcttgccgt aaagaataac ttcaagaaag tttgtggaat
     1201 acctggcaga ttgcgttttt ccatgtatcg cttgatagta tggagacgat tgacataaac
     1261 attggccttt tgacgtgcat taatatcatc tttctcaatt tgtgtcaggc gctcactaac
     1321 tgaaatttgc tcatcttcaa tatcttttag ttgagtttgt aaatcctcaa gattttcttc
     1381 aagaactgaa taagcttggg ttggttcttc ttgatttgaa gttacctcaa caatagctgc
     1441 ctcaaaactc tctaattctg tctgaatacg acgaacatgg cttgcagctg tctcaggaag
     1501 taaataggtc ttgttcaaac gtgcaatatc ttctcccaat aaagtattat tctctttcat
     1561 atgttgaagg taagttggaa gagttgcaag tagattttcc actactttct gagcagcaat
     1621 ttctcgagta aaaatatcat acaaggcatt gatttcctct tgtgcctgtc cattctcata
     1681 ttcggcatta tccaattcca actgacgaat attctcttgg tttttcttga atgcttcata
     1741 aagcaagtgg aaacgcgctt caatatccgt ttcaacaaaa tgataattag catcaattag
     1801 tttacgataa ccggcttcca aatcctgtaa ttgatctggc aattctgtag aaagcgtcgt
     1861 aaccaaggct ggaacacgat ccacaatatg acttaaggcc aaaatgtgat tttctgtatt
     1921 atccaaaatc actgcggctt ccacagggtc acccgatgaa ttcaaggtta caaattgtga
     1981 aaattcagat tggatatttt ctaattgttt ttcaatttca tccaaggctt gaccatactg
     2041 ttctgaattt tcagcaactc tatgctgaag ttcctcaaat aaatccaaag catgaagaac
     2101 acgaccacta tttttagatt cttgcttctc taagtctgcc aaagcattgc gaattgccgc
     2161 aatatcttct tcaatcaaag taatttgact ctcaatttgg tcaatttgat gactggcctt
     2221 gagaaaacga aatgaatggt tatagccttc tgcttcaaag agattatttt caatatcggc
     2281 aaaagagttg agagataaat cgacccattt ttgattccat tcacggaaag ccacttgact
     2341 ttgtccaatc aagtgcatat tttttacagc ttctacttca tcatttactg gaagattgta
     2401 tagttcttct tttctttctt ctagcgcctc taatctcccc tcgtttcgct tacgtagaaa
     2461 gattgccact acataagcca gaactaaaat gactgcaatt gcaaccatta aataaattag
     2521 ttgtccatta gacatatcaa actccttttt tacttgaaac aatcgtaacg attatatcat
     2581 attttttaga ccaagggaac tacttctccc tattttttag acatcaagtg tactatagac
     2641 agcattttct tcgataaact cacgacgagg ctctactcga tcccccatca acatatcaaa
     2701 gattttatct gcttctgcag catcatctac agaaactcta gccatcaagc gatgttcggg
     2761 atccatggtt gtttcccaca gctgatgatc gtccatttca cctagcccct tataacgctg
     2821 aatagtcggt ttggtacgac cttcactata acgggctaaa gcttcttgga gtttgatttc
     2881 ttgatctgca cccggctgga tatattcttt aatctcgctt ccaaccttga caccatagat
     2941 tggtggttgg gcaatataaa catagccagc ttctaggatt ggtttcatat aacgataaat
     3001 caaggttaaa agaagggtac gaatgtgggc tccatcgaca tcggcatcgg tcatcaaaac
     3061 gagtttttgg taacgggctt tcgaaacatc aaattctgcg ccaaatcctg ttcccatggc
     3121 tgtgaaaaga ctacgaattt cttcgttagc tagaatctta tccatacttg ctttttcaac
     3181 gttcaaaatc ttaccgcgaa ttggaaggat agcctgaaac tcacggttac gaccagattt
     3241 ggctgatcca ccagctgagt ctccttcgac gatgaagagt tctgtttcag cagggttatt
     3301 agaagaacag tctgctagtt tccctggaag gttggaaatt tccaaaccag attttttacg
     3361 tgtgacttca cgcgcacgct tggcagccac acgagccttg gcagccaaaa ttcctttttc
     3421 tacgatacgt ttggcaatct gtggattttc catgaggaaa tcggagaagg cttcactgaa
     3481 gaggcgattg gtaatcttga ccacttcgct atttcccaat ttggtcttgg tttgtccttc
     3541 aaactgtgga tttgggtgtt taactgagat aactgcagtt aagccttcgc gaacatcttc
     3601 ccctgttaga ttgtcttcat tgtctttcag taacttattt ttacgagcat aatcgttgat
     3661 aacacgtgtc aaggctgtac ggaaaccttg ttcatgcgtt ccaccttcat gtgtatgaat
     3721 attattggcg aaactcatga cattttcatg gtaacccgtt gtgtactgca tggctacctc
     3781 aactgtgata tcatccatct caccgtctgt atagattggt gtatcaaaga ttacatcctt
     3841 gttctcgttg atatattcaa cgtaactagc aatcccacct tcataatgat aatgcttggt
     3901 ttgttccaaa ccttggcgct tatcagtgat agaaatttga agaccgcgat ttagaaaggc
     3961 caactcttga atccgtttat ttaatttatc aaaatcaaag attgttgttt cagtgaagat
     4021 ttttgggtcc ggtgtgaagt gaacagttgt tcctgtttta tccgtatctc caactatttc
     4081 aagatctgcg acaacatgac cacgacggta ttcttggtaa tgaatcttac cgtttttatg
     4141 gacatgaacg tctaattgag tggaaagggc attaacaact gacgacccca ccccgtgaag
     4201 accacctgaa accttgtatc caccaccgcc gaactttcct ccagcgtgaa ggactgtaaa
     4261 gacggtctca acagcaggac gacctgtttt ttcctgaata tcgactggga taccacgccc
     4321 atcatccaca acagtaatcg aatcatctgg ctcaataaaa acttgaatat ggctggcaaa
     4381 tcctgccaag gcctcgtcaa ttgagttatc aacaatttcc cagactagat ggtgaagacc
     4441 ttcttttgag gttgatccaa tgtacatccc tggacgcata cgaacagcct ctaagccctc
     4501 taaaacttga atttgactgg catcataatc ctgtgcctgc agatttttga tttcttctgt
     4561 catcttattc ctttttctta tatgtctaat acttgtctta aattcacgat actggtaaac
     4621 aagtgggtat caagtcctgc agcttgacct gcttcgatat caatcggccg atcaccaatg
     4681 acaagaccag agctaatctg atacttttct cttaaataaa gcatggattc gggatttggc
     4741 tttctcttaa agcctgagct agaagtcacc acttctgtaa aataagctgc tatagaggtt
     4801 ttttctaaaa tttccaaaac ctgatcattt cgatgagaga ccaaaaaatg acggccacct
     4861 tgatttgaaa tgtcttccaa taggtcagaa actccttcaa ataaaatcgg gtgttcaagc
     4921 tctctagctt cattttcctt gtacttttct aaaaaattct ctaaattggg agcgaatgtc
     4981 tcaatcgcaa aaggagtaga aacctttaaa gcttgataga cactgtcatg gtcttgtgtg
     5041 ataccataca gtgccaatgt ttcaacaaat gcagctgttg aagtttcata attatccagt
     5101 aaagttccac ctaaatccca gatgtaatcg tgatatttca tacccttcat tatagcattt
     5161 ttttatgaaa aaagcgatga tttccctgag ttttccacat aaaaaacgag agaataactc
     5221 ccgttttact gatttttacc aaagacatct cgatagagca ttcctgttcg taaactctct
     5281 gcgtcccctc ctagttgctc caccaactcg taggcaaagg caagggctgt tgaaggaccc
     5341 cgactggttg tcaactgacc atctaccact actgtttcct tgacgtagtg accatcaagg
     5401 atttgctctt gaacgccgtc ataacaagtg tatcgcttat ttttcaatat ctctgcttga
     5461 ttgagggcaa ttggtgccgc acaaatggct gctagtttct tcccttcttg ctcgaagctt
     5521 tgcaattctt gaatcaaggt ctgattatca cgtaaatgtg cagaaccagg catacctcca
     5581 ggaagaacaa tcatatcata gtctgataaa tttccatcaa agacatgatc tgctcttact
     5641 tggattgcat gcgaacccgt tacttgctct tcaaaaccaa ccatatcaca tgtgatattg
     5701 gctcgacgca agacatctac aactgtcaag gcttcaattt cttcaaagcc ctgagctaac
     5761 ataactgcta cttttaccat gattttctcc ttatttaatt tgttttaata caaccttttt
     5821 ccgtttgaat gggacttttc cgctcttttc ttcagctaga ttagtctggt aactcatcga
     5881 taaaagcaaa ccaacaccaa tcagattact gataatagct gatccccctt gcgaaatgaa
     5941 aggcaaggga atccccgtca aaggaagtag tccagtcaca gcaccgatat tctcaaagat
     6001 gtggaagagc aacatcataa tcaaacctgt ggaaatataa gtgtagaact ggttatttga
     6061 tttaagagta atcttcaaca tacggtaaat caacatgaga tagagggcaa taaccaggac
     6121 agagccaata aagccaaaat cttctgcaat aaccgtaaaa atcatatctg actctcgaac
     6181 tgggataagc agattcgaag cattaaatcc ctgaccaaat aagccaccac tcccaatggc
     6241 aatctgccct tgagcctgct ggtaagtcgt tgtttgggca aactcaaagg gattgagcca
     6301 agccaaaatc cgattgattt ggtaggtcgg cattccaatc tggtgaagaa aagctcgtcc
     6361 gtccttgcta ataaagatag ctaagaaacc agcaactcct gttacagcag tcacaaatac
     6421 tgggataata attttccaag aaacccctga taataaaacg attcctgaga aaatggctac
     6481 aaaaaccaaa gccgtcccca agtcactttg aagtgctaaa agaactagga ctggaatggt
     6541 aaagagaatc atccagaaaa ttaacaaaaa gtccagcgga accgtgcgtc tccattcctt
     6601 atgtttcttt gtaaattgga caatgacacg agccaacatg aggatatagg atatcttcat
     6661 aaattctgac ggttgaaata gggtaattcc atttattgat acccagtttt tggcacccgt
     6721 tgatgcaact aagcttggat tataaaatac aatcggcaag atcataagtc ccaagcctaa
     6781 aatatataga aagggggtca ccttccaaag aaattctgta ttaaagagca tgaccacaaa
     6841 accaatcaca agccccaagg caatccaggc gacctgctgc cctaaaatgg gcagaatatt
     6901 attgggataa tcatgactaa cggctatata gatagccacc acaccgatga ccagtagaaa
     6961 aaatactggc aagagcaaac tgtaatcgac tcttgagtcg agagaacgtt tcatatatac
     7021 taaccttata ctttcataca atactattta tcaaagttca ttaaaaaatc tatcaatagc
     7081 ctcgtcaact tcggatcgag agatggtttt aacagtcgct tcttctgcta gagatgctac
     7141 tatttgtttg ccgtatcgtt ttccgacgat tctcctatcc aaaataagag ttaaggaacg
     7201 ttggtattca cgtctcatac ttcttcccaa agcctgtttt aaacgaataa tggccattgg
     7261 caattgataa tcataaaagg catttttccc ttcttgattc agttcttgat taatcttttt
     7321 cgtcaagggt tcttgaggat tttggaaagg aagcctcggt acaacttgaa tcacagaagg
     7381 atggcttgaa aaatcaactc cctcccagaa acttgctgca ccaagcaaga tttgttgttc
     7441 acctttttca aagcgtttct ttagctgatg aacatcccca tttttatact gggccaagtg
     7501 gctaactgta agtaaatccg atactgctag aagcatgtct ttagcggtaa agagaaccaa
     7561 aatcggttgc tggaaagctt gaatttccac tagtaaagca gctacctctc tggcatagac
     7621 ttctaaggag gtttctgtta ccagagggaa atctttgacc atgaccactt cttgttcctg
     7681 ttttccccga gattcaatct tgacaaattt agcttcagga tagcctaaaa ggtctgccaa
     7741 agaaaccctc tgactaatct caagagtagc cgatactccc aagacttggc aactctcagg
     7801 aagtaaagag gacagaagag tacggcctga ttttgtagaa gaaatctgaa ttttcttttg
     7861 actcgtttca gttacttcaa gccagtaatc accttcagct gtaaaatagc gaaccagctc
     7921 atcaaagtct tctacttcca attctgaaaa atactgatgg agattgtcca gagaatctaa
     7981 gatatttttc ctagatttgc cagactgaaa ttgttctatc aagtagagac actcaaagcg
     8041 aatactttct agtatccgtt gttgaaccct gttttcttct cctactaaag ccttatcaat
     8101 taaatcgata atagattgta tatcgtaggt ctcttgaagc agattttcta gagctaacaa
     8161 aatcttttgg acttcatcaa taatcagtaa acggtcactg acaaattcag gattatcttc
     8221 aagtctggtt acgagatagg catgattagt cactaaaagc ttgcaagtct ctgccctttc
     8281 ttgactacgt ttccaaaaat cttccgtcac aaataagctc tgggatgata aattcccatc
     8341 atgacgaagg tctgctagaa aatgttggta acggtagagt tgcccgattt catccaaatc
     8401 tcctgtctct gtctcagtaa gccagaccaa gacttgcatt ttaaagcgtc taaataagcg
     8461 attttcatca ttttcctgca aggaatgata aaaggcatcc aacttcagat aattttgtgg
     8521 tccctttaag ctatgaatat ctgtatggaa cacttccttg aggcgtttac cttcttcttc
     8581 catgatttga ttttgaagaa tctttgtcgg aacactaaga acaatttgtc gctctttgga
     8641 ttgagataaa gcgggtaaga gatagccata ggttttccca atccctgtcg gcgcttgaat
     8701 cagagagaca ggttcatctt tcaatagcaa gccaacctct ttagcaaaac tttcttgttc
     8761 ctccctcact tcaaggttca acagagaaat atttttagaa aagtcttgag atagttttcg
     8821 tagctccaga gaagctgccg ttttcttaaa atacagacct tgaacttgga ccaagtctgg
     8881 agaactcagg atagattggt tgcgataagt ttcctcaata accaggtagg actcatatag
     8941 gagagcgtca gccatttcca gcaagcgttc caagagacct ttaggaagct gggtcatctt
     9001 ttcccgtaaa aaaagaagta attctgctgt agcttgggca tctgaaaggg ctgtgtgtgc
     9061 gtgtttaaga ggaattccta attctcgaca caaaatcggc aagctatatt tttccagttc
     9121 agggaaaaag acctgggcca attcgaccgt atcaacacga gggtttctta gctcatagcc
     9181 ttcaaaaaat aaattttccg ccaagagatt agcatcaaac tgaacattat gggctacaaa
     9241 aatcccatcc tccaccaagt caaatatttt tctggcaact tgcgaaaaat caggtgcttg
     9301 cgccagacgt tggtctgtca atcctgtcag ttctttgata tgagcatcca agggttcatg
     9361 tggattgaca tccgtcgtat agtgatcgac gatttctcca tcctcaatca cgacaattcc
     9421 cacttggata attttagcct tactacctgt gctagttgcc tctaaatcca ccacaacata
     9481 gcgattacca atcgttttca ttataaaaaa ttataccaaa aaaagggcca tttggcacct
     9541 gcaaacatag gataattttc aaactcaaga acactacttt tcttaaaaat cccatcgaat
     9601 agagcattct agcctgctga tttttgtaaa atagtgaaga aatacgaaaa attgagagaa
     9661 gaaatgtttg catcttcctt ctctcaacga atcatgtatt ttatctaacc atgtcaggat
     9721 cgtagtcata aaatcctgta tcaaggaaac ggtttttagg gtgaagttta tgaacttctt
     9781 catccagcaa gaaggcttga tcatggctaa agttgccctc ttgaatcaaa ttacgcgctt
     9841 ggataaagag ttttgcaatc tcaacaaagt tctgaccagg agtgtagagc ccttctagtt
     9901 tccagcgagt aaagccatgc tccaccaatt ctgttaattt gatcatcaaa tcaaggtcat
     9961 tgttggcaaa gatatgggtc ccatgattat cttcaaaaat ggaatagtgg ctctctggat
    10021 cacttggctc agccaagaag aggtcacgtt tatgcgtctt ttcatcatcg atatgtgtaa
    10081 agttatagta gttttgcaag agtggacgtt tagaatgatg gatgacgcta gcaccgtaaa
    10141 ccaaaacttc agcaggaatt tccaaaatct ctggcatttt gaaaagttca gctgatggaa
    10201 tttcacgcgc caaaacagcc tcagatgcgc cagccttttg tccccagaag ttaatctgac
    10261 gactgctagt taccatggtt gaagcatcgt agatggtctt aaatgaataa ccatcgcggt
    10321 taactacgta aaagacgcct gcatccccaa tcgtaatata gtctgtcttg atttcttcca
    10381 agaagtctaa gaaaggcttg atacggtcca tcatatcttg gtgcatgaga gcattgaccg
    10441 caacgatcaa ttccttacca gcatcatgaa ccaacttagc gatttcacgt aattggtcat
    10501 aactaaaggt cgttggcaga cgaagaccaa aatctttctc accgacatag atacggtcta
    10561 cgccagcttc gagtagttgt tcaacttgtt caatactttc agcagttgct gtaatgacaa
    10621 tcttttccat aggaaaaatt ataccacatt tctccaaaat cagccatgct ttgaaaatga
    10681 aaagggactt tattcttttt gtaacctttc tgtaataatt ctctgccgaa aaaatgataa
    10741 aataggtatg tactgttaag gagagaatca tgcccgtaag aaaattacaa tcctatgagg
    10801 tagactatca agaagaatta aaccagcagc ttcctcatta ccaagcttat acacctgaag
    10861 cgcaatctga tgccaatctc aaggaaatcc tattttttat taatatcgct gttttttgta
    10921 tctgtattgc tatctttagt tttatctttt tagcattaaa attatcaact gctcttgcct
    10981 ttgccgcagc aatcggattc agcttacttg ttttaaaagt tcaacggtct attatcaaac
    11041 gaaaacgtag aagataaatc caaaatatcg ccccaattgg agcgatattt ttattttttc
    11101 tttttagatg gtgtctgaat ggcaatcttc acttcaaaga ttgttccctt gggtttatta
    11161 tctttgacag taacagttcc ttttagagca tctacaattt gcttggctag ggataatcct
    11221 aaaccaaaac cacctttttg ccgggttcta gccttgtcta ctcgataaaa acggtcaaaa
    11281 attttctttt tatcttctgt cgaaataccg attccattat cagaaacaag taaataaaga
    11341 ttgcgatcgg tcgccgagat aagaaaatca atttcaccat cctcctcagt atacttgacg
    11401 gcattatcga aaagaatggt catcagttgt ttcagaagaa gctgatctgt gacaattgtt
    11461 cgatggatac gattttcaaa acggaagaca cgattatttt ccgaagcaat catctcatag
    11521 tttgtgaaag ttgtattaaa aaagctagtt ggaacttctg caagctccgg cttaatccca
    11581 tcatctctcc gagctaagtt cagcaagctt gtcgttaaaa aacgcatatt tcggacttct
    11641 tccaaactcg atgcaatgct ttcgctcaca tccataatgg tagcttctgg cttacgaaaa
    11701 agggtctcta agcgattttg caaaactgcg agtggagttc gtaactcatg actggcattt
    11761 tccacaaaag actgttgctt ctgcatactc tcaagcaggg gcctaacact gaccctagct
    11821 agatagagac tggcaagtaa agacaaaatc cagaaactag ccatcacgac cacaatcaat
    11881 tgctcatgct tttgactagc ctgctccaac tgactggtat taatcaagac agcagcatac
    11941 ttgatattgg ttgaaaccga actaatattg gtctccatca aaatcacacg atagatttct
    12001 tcctgcccat agctattaaa aacctgaatc tggtagatat gtcctagttc tttcttttct
    12061 aacttaatct tatccaagcc caaaaatcga tttccagaaa gaagttgagt aaagtcttta
    12121 tcaaagagaa tgacttccgt attggaactg acattaggtt ttatttctac tttactagcg
    12181 tccgccctag cattttctaa atctttaatc tcttctgttg ccctatttat agccagctga
    12241 ataactgctt gaggattttc actcagtcca tgaagcttat cgtccaccga agtataaaga
    12301 ctcgaatgca tgacttgtaa aataatcaga gtcattgtag aaaaaatcag ggtgaagaca
    12361 ccgaagttgc ggataaaata actaaagtca tccgcatacc atgttttttt aagtttactg
    12421 aacatctttt aaaagatacc caacactacg caaagtttgc aaattctctg caaaagtggt
    12481 tccctttaat ttcttacgga cttttgaaac atagacttcg acaaccgaaa tcgttgtatc
    12541 actatcaaat ccccatagac ggtcaaaaat ctgcgtctta ggcaaaatca cattttgatt
    12601 ttgaaggaaa taaactagta agtcgaactc tttccccagc aattcgacag gagtatcttc
    12661 aactttaacg gtattggttg ataaattaac cacgatattc ccataagtca aggtgttttc
    12721 attaaacttc cctgaacgtt tgagaagggc ctgaatccgc attttaagtt cttctaggta
    12781 gaaaggtttg gtcagataat catccgctcc cagttcaaat ccatgtccct tgtcatccaa
    12841 actttccttg gcagtcataa tcagaactgg tgtcgtaatt cccttttcac gcaattcttt
    12901 taagacttgg aaaccatttt tttctggcaa catcaaatcc agcaaaatca agtcatagac
    12961 accactctca gcttcgtaga gaccttcttc tccatcaaat acctgcataa catccgcaaa
    13021 atcgtctaaa aagtcaaata ctgaatttga cagacctagg tcatcctcaa ccaataagat
    13081 ttttatcatg agaaactcct ccttattaaa actattatac caaatttgcc ttaaaaaaaa
    13141 ctcaactctc tgcattttac atgagatagc tgagttttct ttttatttta ggcttattta
    13201 tgcatttccg tattgaagaa caactgcttc gactgcagct ttttcacggc taatcaagtc
    13261 aacacgtgct gcaatttcct tgattcccat accgatgtta cggctaagag caaggtcaga
    13321 aagttgcggc tcaaagaact ccttgtattc cgccaagcgt tgctgagtct taaatacatg
    13381 agcaggaagg ataacaaagc tatcaaagct catatctcct ccaagggctg ccttaatcca
    13441 agcccagttt tcacgcgccc aagaccaagc tgttttctga gttgcttgat gagctaggaa
    13501 ttggtaatac caagcagaca agtcctgtgg tttgaccaca aatttgtcct tccaagaagt
    13561 aatcaggttt tggatattat ccgcatctgt actgtatgca agagctgctg ccaactggcg
    13621 tttaaagaca gcatctgttg cgtgagtata agtatcaaga taaagtgcta acaagtcttt
    13681 agtctcatga tgtttcatct cattaatcag aacttgtgag cgaatagctg ctgggagtcc
    13741 tgcaagattc tccttgtgtg ttgcgaagat ttggctagcg acttgactag cttctgcatc
    13801 atttgagcga atcatcatcg aaacagccag ctgacgaacc aattcatcct catctgattc
    13861 tccgtcttta gcttcaaaac caagacggtc atagttatga cgagccaatt tagcaaccag
    13921 tcctttgaag gctgtttcag catccgttcc ttcatcaata aagcgctcaa gggctgaaat
    13981 cacttgagaa acagctgaaa ccaccagata agactcttcc ttagcaagtt tatcaagaac
    14041 tggaagcaag tctgcataag aaatgtgccc tgcctcagcc aacaaacgac gttcttgaac
    14101 aatttgcagt ttgcttgtgt tatcaagtgt ctctagctca gcaagaacag cttctaacaa
    14161 gtctccttga tagtcggtaa tatagtgggc agtattttca gtgttgagac gaagagctcc
    14221 ttcattttca gcaagaagag ctgcgtagcc agggatttcg atactttcag tttcgagtgt
    14281 atcaggcaag cctttccagt tgctattgag gggcaccacc cagagacggt tcttgtcttc
    14341 gttctcaccg atgaagaatt gtttttgtga aatcttcaag acatcatttt caactttgac
    14401 agtaagaact gggtaaccag gctgttccaa ccaagaatcc atgaaggctg cgacatcacg
    14461 tcctgacgct tgaccaaggg catcccaaag gtcactacca atggtgttgc tgtattggtg
    14521 tttttcaaag taggcgtgca aacctttagc aaaatcagca tctcctagcc aacggcgaag
    14581 catgtgcatg agacggcttc ctttggcata gacgatagcg ccgtcaaaga gtgtattgat
    14641 ttcatctgga tgtttaactt cgacgtggac agactgaacg ccatcagtag cgtcacgttc
    14701 aagagcaaga ggtactccac ctgtttggaa atcttcaaag atattccagc ttggttcgat
    14761 ggtatccaca cagacgtatt ccatcatatt agcgaaactt tcattgagcc aaaggtcatc
    14821 ccaccatttc atagtcacga ggttcccaaa ccattggtga gccaattcat gggccacaac
    14881 aagggcaact tgttgacggc tagcaaatgt agagttctca tcgacaacca agtaaacttc
    14941 acggtaggtc acaagacccc agttttccat agcaccagct gagaagtcag gaagggcgat
    15001 gtggagagat tgaggaattg ggtacttaac tccatagtaa tcttcgtaaa actcgataga
    15061 gcgaacagcg atatccagtg agaaatcaag atttgaaagt ggatgtgctt tggttgagta
    15121 gacacctacc agggtaccat ttttagtttt agcggtcacc ccttgcaaat caccagcaac
    15181 aaaggccaac aagtaagaag acatgcgagg tgttgtctca aacttccaga tacctgtttc
    15241 cttacggttt tcaacatcga tttctggcat gtttgacaag gccaattcac cttctgcttg
    15301 gtcaaagcga agagagaggt caaaagttgc tttggcttca ggctcatcca cacatgggaa
    15361 agcttcgcgc gcaaaatggc tctcgaactg agtagacaag acctccttct tgactccatc
    15421 aactgtataa taagaagggt aaatccctgt catgttgtct gtaattttac cagaaaaggc
    15481 aagaaccaat tcaacttgac cagcctcagc caattcgata tgaagggctt cattgtcatg
    15541 gtcaactgta aatggacgag cttgacctgc aacttctaca gaggtgattt ccaagtcttt
    15601 ttggtggagg gagatgcggt cactctgtgc ttgaccagtg atggtcactt tcccagaaaa
    15661 agtcttggtc tcacgactca aatctaaaaa taaatcataa tgttcaggaa caaattgctt
    15721 aataaaatgt tcaactgctt gcatagtttt ctcctattct aagtttaaga gctgctgctc
    15781 ttcttcaaac aaacttatta tatcatattt tgcttgagaa aaaaggattg gacagcgatt
    15841 tccaaaactt tcttccttct aatagtctac agtgggtaga ccttgcgaaa ttcttctaaa
    15901 acaaccttgc tttcaggtgt aaaagtcagc cctacttcac ccaaacagtc tgtgaaaaag
    15961 tcctcatgaa cctggcgcca ataggcaagt gatttgtctc cctcaccttc cttaaaggca
    16021 tgttgcgcag aaacttgatt gaagagttca acagaaacct ttgtaatttc gacaacgcag
    16081 acagcctgat tttgactatc taaaatgaca tcgaaggtcc ctacttgggg aagtggttcg
    16141 tcttctagta catagaggtc ataggctgat gctgttgctg tcttttctcc tttaaacacc
    16201 aaatccgcta aaaggtctgg ttcaactcca aaagcccaag catcgatttc atctccgatc
    16261 aaaggattga tttgcttgta tttattccac atttcttgcg gtatcatggg tactcctttg
    16321 taatttttta ctttcttctt ttatgtgttt aagatgatct ggatggtcaa tctctaaatc
    16381 aaaaatctct ggaatagaac tgtagtggat aatgcacttg acacccaact gattcatttt
    16441 ttgtatgaaa gaagtattca gatagcctgc tacagcaaaa ttaatcttgt tctttcttgc
    16501 tttatcctgc atatctctta gcatatctaa cattattgga ctttccatat catgccattg
    16561 actgtttctc atagtcgcaa aaacaaagga agtcaaatca ttcattccaa ctacaatctt
    16621 tgaaatgccc gtttccagta tactagataa gtcaaaatac gctgacggta attcaatcat
    16681 cgttccgact ttcccagtaa agccatactg acgcaatact gtaatagctt gttttaattg
    16741 gtcggcatca ttgacaaaag gaaaaataag agacagattg ggattggttt gataaacttc
    16801 tgtaacgaca tgtgattcag cctgaaattc atccaaacac gccagtaaac gcctggttcc
    16861 tctatagcca aacaagggat gcccttcgtc aaaaaactct ctagtccccg ctaaacaatt
    16921 ggcttctgta ttcgttaatt cagaaaaacg ataccaaact tccttatcta agtaaaagga
    16981 gcaaatagta tcaagataat cttttacaaa ttgctgacaa cttgctaata tgatgttttg
    17041 attaagctct ctcaataagt attccccacg aatcatgccg acgtggtgaa atagttgagg
    17101 ataaattttt tcaagaattt tttcgccact aagggcaagt tgatttctca tagccattca
    17161 cctcgtctta aaagatacaa tatcatatat aattatatca aaatttcctc tagttcaaaa
    17221 gcttcataag gttcagataa ctcatatcct aaaaattctg ctactttttt ggaagcctca
    17281 ttatgagcat cccaaagtgg aaacatatct ctatttaaac tctctagaat cattgcagca
    17341 ccaagctttt tagcaaatcc atttccttgt tcgtttggtc tagttgcaac ttccacttca
    17401 actgctttac ggtaaactaa ccctgaggaa atcccagcaa tcagttcatt atttttaaga
    17461 atcacaaagc caaatccacc ttttaaaaca aaatcctgat aggactcaaa atccccctgt
    17521 aaatcctgtg accattcttc cgtagaaaag cagttataaa tatgattatc aataggcaca
    17581 atattgtaac cttcctctaa atgagtaact agattattta aaaattcaac ttgaaaattt
    17641 gccttatctt taaaagaata gcgagtaaaa gaatttagcc ccacttttcg atgcagaaaa
    17701 tcttgccaat tagtattttc tgaaataata atcttataat ctaaaccata ttttctaaca
    17761 aaatcttccc aaaatctgga atccaactcc cctgctaggt atagaaaatt cccaacatca
    17821 taaaagcttg ttgtcctatc attgtttcgg tagacagttc caatttgaga tttaagacca
    17881 tagagaacca tatttttctt ccatgtttta aatagttcca ttatccctct acttcacctt
    17941 ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag acttaacctt
    18001 caagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc aaatatatcc
    18061 aagtgaatca ttcgcaccat cagacacagc ttccgaagtc gtaacttgag gtgcactctc
    18121 attcatttca acatcataca aggccatgac atggtgaacc ataaaatttg ttaactcttc
    18181 tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa atcccgtctc
    18241 ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct gactgcctcc
    18301 aggtagatca taccgatgtt gataagggcc tctcgctttt tcaatgcaaa gtaacttccc
    18361 attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc aactcctcct
    18421 acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg ctcgcttttc
    18481 cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag cgcttgattg
    18541 gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca gcggtcatag
    18601 ctgtcttgac tgctcctgga gcgatcccaa agacctgaat cccagcttca gcatagtcta
    18661 gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag gcgtgaccac
    18721 ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc tttttatttt
    18781 ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag ttgatttcaa
    18841 aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca tccaaaactc
    18901 cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt tccaagtcca
    18961 aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt tcaccttggt
    19021 caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc aatccgatcc
    19081 ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca atccgttgcc
    19141 aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc agacacgttg
    19201 attaggaaat agggtgtcac ttcaagtgca agcccatttt gctcgatggt atcaaagagt
    19261 tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt agcctttaag
    19321 ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa ttctcccctt
    19381 cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt tacatcttct
    19441 tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc ttttcttgtt
    19501 aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt ggtacctaca
    19561 actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt tgaagaggtt
    19621 actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa tttctcattt
    19681 ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg aatgaccaca
    19741 tcgtgtaatt tgcaatattc aaaaatgctg ccatctcgca tagctgcttg actatcttcc
    19801 atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa ttgtagctga
    19861 ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat aggattttga
    19921 ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa ggcttctgct
    19981 acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc tagatgatca
    20041 atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt agaaaaatca
    20101 aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat cttttctctt
    20161 aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc acgaccataa
    20221 atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac aagctcttca
    20281 acttctttta cagacttatc ttttattctc atcattccga gaacaatttc tgataattct
    20341 ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa tttctaacat
    20401 tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat acttcactcc
    20461 attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg acagctaaag
    20521 gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa cggagcagag
    20581 aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc gcttctttcc
    20641 aattccaaat accgataact agcgaaatcg taaagacaga caaactatcc cagggagccg
    20701 gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct aaaacaacta
    20761 gaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga gaatcttgga
    20821 ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa ataagaagtt
    20881 gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa tcacttagta
    20941 gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac tctttgatag
    21001 aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc ttacctagat
    21061 aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc atcaaataga
    21121 tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa ctttcccaca
    21181 actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg cttgtttctt
    21241 cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct actttttgac
    21301 tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct ttcattaatg
    21361 aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt atccattgat
    21421 ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta tcaaatccag
    21481 cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca atcatatcca
    21541 agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact tctcccttct
    21601 aatctatttt gtaataccta ctagtaactt cacctatagt atattacttc tacactagtt
    21661 tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca gcgtcgccct
    21721 accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac tgtgttttga
    21781 gctgacttcg tcagtttcat ctacaacctc aaaactgtgt tttgagctga cttcgtcagt
    21841 ttcatctaca acctcaaaac tgtgttttga gcaacctgcg gctagcttcc tagtttgctc
    21901 tttgattttc attgagtata aataaaaaaa cagaactagc ctgaactagt cctgtctact
    21961 tttacccaat cacacttcca tttggtacag ctggatcaac tgtgagaagg gttaatttgc
    22021 catcatgttc agctgagaga atcataccct ggctgacata ttttttcatc attttacgtg
    22081 gtttgaggtt agcaacgatt tgaactttct tgccgaccaa ttcttgttca tttggatagt
    22141 atttggcaat tcctgaaaga atctgacgat cttctccatc accagcatcc aagcggaatt
    22201 gaagcaactt atctgaacct tctactttag acacttcttt gacttctgca acacggattt
    22261 caaccttgtc aaagtcttca aacttgattt catccttgtt tagtttgagc tcaacttcgt
    22321 ccggattcca ttctttttcg actgctggtt tattgccttc catttgttcc ttgatatagg
    22381 cgatttcttc ttccatattt agacgtggaa agataggtgt tcctttggca actacagtca
    22441 catctgctgg gaagtcagcc aaactcaagt tttcaagact agaaacttct tccaaaccaa
    22501 gttgagtcaa aactgcacga ctagtttcca tcataaatgg ttcaatcaag tgagcaacta
    22561 cacgaatgct ggctgccaag tggctcatga cacttgccaa ttggtcacga agagcttcat
    22621 ccttggccaa gacccatggt gcggtctcat cgatgtattt attggtacga gagatcagag
    22681 tccagactgc ttcaagcgca cgtggatagt caactgcttc catgtgtgta tggaagtctg
    22741 cgattgattg ttctgcaacc tcagcaagaa catgatcaaa ttcagtcaca ccttctacat
    22801 aggcagggat ttgtccatca aagtacttat taatcatgga aaccgtacgg ttaaggaggt
    22861 tcccaaggtc attagccaat tcatagttga tacggccgac atagtcttca ggagtaaagg
    22921 ttccgtctga accaactgga aggttacgca tgaggtagta acgaagtgga tctagtccat
    22981 aacgctctac caacatttca gggtaaacga cattcccttt tgacttagac atttttccgt
    23041 ctttcatgac aaaccaacca tgggcaatca aacgatcagg taatttaaca tccaacatca
    23101 taagaaggat tggccagtag atagagtgga agcgaaggat gtcttttcct accatatgga
    23161 agactgttcc attccagaac ttgtcaaagt taccatgttc gtcttgagcg tagccaagag
    23221 ctgtcgcata gttaagaagg gcatcaatcc aaacgtagac aacgtgtttt ggatttgatg
    23281 ggacaggcac tccccatgta aaggttgtac gagataccgc caaatcttcc aaacctggct
    23341 cgatgaagtt gcgtagcatt tcattaaggc gaccctctgg cgtgataaat tcaggatgag
    23401 ctttgaaaaa ttcgaccaaa cggtcttggt atttgctaag gcgaaggaag tatgattctt
    23461 cagaaaccca ttcaacctca tgacctgatg gagcaatacc accagtcaca tttccagctt
    23521 catcacggaa aacttctgcc agctggcttt ctgtaaagaa ttcttcgtct gatactgaat
    23581 accaaccaga gtattcaccc aagtagatat catcttgagc aagtaagcgt tcaaagacct
    23641 gtgcgacaac tttttcatgg tagtcatcag ttgtacggat aaatttatcg tatgagatat
    23701 ctagtaattg ccagagttct ttaactccaa ccgccattcc atcaacatag gcttgaggtg
    23761 taataccagc ttcttccgct ttctgctgga ttttctgacc atgttcatca agacctgtca
    23821 gataaaatac atcgtagccc atcaggcgtt tgtaacgtgc taggacatca catgcgatag
    23881 ttgtgtaggc agaaccgata tgaagtttcc cagatggata gtaaatcggc gttgtaatat
    23941 aaaaattttt ttcagacata atttttcctt tccaggcaaa tgaaacctgt ttttctaaca
    24001 cttcattata tcatattttt aatgaatttc gatagggaaa tccatacaaa aacaagatag
    24061 acgagtgtcc atcttgttga tctcattcat aacgaagggc ttcaattgga tcaagtttcg
    24121 atgccttgtt ggctggcaag actccaaaaa tcataccaac actagccgaa actgcaagac
    24181 taaatagggc aactgggatt gatactccaa cttctatacc ttctattaaa ccttgcagta
    24241 acaaacctgc taaggcagtt aaaccacttg caattgtcaa gccaattaag ccacctaaca
    24301 aggtcaaaat catggattca atcaaaaact gaattaaaat attggcacgt gttgcaccca
    24361 aagccttacg aagaccaatc tcacgagtgc gctctgtcac cgaaaccagc atgatgttca
    24421 tgacaccagt tcctccaaca aagagagaaa tccctgcgat ggaactaata atcgtcgtca
    24481 taaaactaaa cgattgttga atttctgcaa atacaacgga ctcatctgcc acctggtatt
    24541 ctccctgttg taagcctgca agctctgtca tttttcgtgc cagttctgga cccagagttg
    24601 gggttaaact ggtatcattc actcgaaaga caatactagc tatttcatct atattaaaat
    24661 tcgcagcaag ggagatattg gtagtaatag gcaagccacc aaacccatat atttttgatc
    24721 ttttagcctc cggactagta taaaccccaa tgacccggta actaaatcca ttgacttcta
    24781 caaccttgtt aatagcctct tgaggagatt caaataaact aatggacaat tcctcatcta
    24841 gcaaaatgac acttgcaaac tctttgaaat cttgctctct cagactacga cctgcaataa
    24901 tttcattctt aacagcgtcc atgtaagttc tgtttccacc tgtcaaatta gcattctcaa
    24961 cctttttatc ttgataggtc aagatggcat tcgttgaatt ggttacatag taactatcca
    25021 ctcccttcag tttagctgcc tcttgaaccc aggattcttg cggttttggc ggttcaacag
    25081 gaacttcctc ttcctttcca gaaaccgtaa aagctgattg tttctgagta aaagacccat
    25141 ctttactttt tttaggagag aaaaagacgc taatattttt ctgagattta gtcatatctt
    25201 tattgacttg acgagatagg gaatcaccca aagccataat cacaacaact gatgaaacac
    25261 cgataataat cccaatcata gtaagcaaag aacgcatctt gtgagccatg atagatgaaa
    25321 aggcaaattt cagattctgc atcttagttt tcctcctttc ctaactgagc actgtcagac
    25381 gaaatgaccc catcccgaat gacaatctga cgtttggcat aggcagcaat ctcaggctca
    25441 tgcgttacca tgataatggt ttttccttct ttattcaaat caaccaataa ttgcataatt
    25501 tggttacctg ttttggtatc caaggctcct gtcggttcat ccgctaggat aatagaagga
    25561 ttgtttacca aggcacgcgc aatggctaca cgttgctttt gaccaccaga taattctgaa
    25621 ggtaaatggt gactacgttc tgtcaattca accttgtcta aatattcctc agccaacttg
    25681 cgacgttttg aagacgaaac tcctgcgtaa atcaagggca attctacatt ttgcagagca
    25741 ttgagcttcg atagaagaaa gaactgctga aagacaaaac cgatttgttg gttacggacc
    25801 ttagctagtt gtttttcacc aagcccagcc acttcttgac cttcaagata atattctcca
    25861 ctggttggtg tatccaacat gccaatcgta ttcatcagag tggacttacc agacccagat
    25921 ggtcccatga tggctacaaa ttcaccctca ttcacttcta gattgatatt tttgagaacc
    25981 tgcagttctt ggtcaccatt acggtagctt ctgaagatat tttttagact aattagttgc
    26041 ttcatcagtc ttcacctctt ttccttcttc caaggaagat gttggattac tgatgacctt
    26101 agcaccattc gttaaaccag aagtgatttc ttgattttct gcgtcagcat ttcccaatga
    26161 aacctcaact tttttagcct tttgttgttc atccacaatc cagacataat ttttactatc
    26221 atccattact agactgctaa caggaacaag aatagcctta gttttgcttt taacctcaat
    26281 gttgacagaa aaaccctgtt tcaaatcacc aacctcgcct gtcacatcaa tagtataagg
    26341 gtatttagaa cctgtattat tcccggctgc tggactagct gcttcaccat tgtttttagg
    26401 atagtcagaa atatagctta atttcccagt ccatttttta tcaggataca ctttagaagt
    26461 aaagcttact tcttgaccta cagaaaggtt ggctagattg tactcagaca attctccctt
    26521 gacttgtaaa ttttcattgc tgacaatatg aaccataact tggctcgccc ctgttggaga
    26581 tttagaaaca ttgctattga cttcgactac agttccctct agggtactga gaacagttgt
    26641 tgcatccaat tgactttgag ccttgcttaa ttgcgccgca gcatctgcac gcgcatcacg
    26701 ggcatcaccc aattgagcgt caatagaagc aacagaattt ccagccactg gagttgggct
    26761 ttgcaccgtt gcatcttctc ctcctactgg cgctggtaac tgtggagccg gagctgaagc
    26821 ggcttcattt cgtgcttgat tgagttcatt gatatgacga tctgccttag ctactgctcg
    26881 actagctgaa tcataggccg cctgcgcttc tgaactactg tacttgacta aagcctgccc
    26941 ttcgctgatc ttatcgccca cagaaacaag gatttcatct aaatcaccct tactagcatc
    27001 aaaataaaca tattgttcat tttttgctgt tactgtccct gacaataaaa cagaggatgc
    27061 cacgcttcct tccttggcaa caacaagatg agtaggctca tcttttacag cagtctgaga
    27121 aggttgtcta aagagtaaaa tccccccggc acccaataca actacactcg cagcaccgat
    27181 tgctgcatac agttgccact ttttagcttt accattcttt ttcttcataa tgaaactcct
    27241 tttctttttt acaatacttt gctattatac caaatttccc tccagcaaac aatgcagttc
    27301 agatggaaat aatggcagtt caggattaaa caatcgttcg gaattttgct tttctattgt
    27361 actagatata taatacacta tcttgactta tttggcaagc ttttttgcaa ttttttgtgc
    27421 gtagcagatt tttgcaatca aatcaaaaaa agaataaaat ataactatca aaaaagacac
    27481 tctactattt aaaagattac aaaggagttt tcaatgagag aatatgatat cattgctatc
    27541 ggtggaggta gcggaggaat cgctaccatg aaccgtgctg gtgaacatgg agccaaagca
    27601 gccgttattg aggaaaagaa attaggtgga acctgtgtca acgtcggttg tgttcctaaa
    27661 aaaatcatgt ggtacggggc gcaaatcgct gagactttcc atcaatttgg agaagactac
    27721 ggctttaaga ctactgatct taactttaac tttgcaaccc tacgtcgcaa tcgtgaagcc
    27781 tacattgatc gcgctcgttc ttcttatgat ggtagtttta aacgcaacgg tgtagacttg
    27841 attgaaggtc atgctgaatt tgtagattct catactgtaa gcgtaaatgg tgaactgatt
    27901 cgtgctaaac atatcgtgat tgctacaggt gcccatccaa gtattcctaa tattcctggt
    27961 gctgagctag gtggctcttc tgatgatgta tttgcctggg aagaacttcc agagtcaatt
    28021 gccattctag gcgctggtta tatcgccgtt gaattagctg gcgtactcca cacttttggt
    28081 gtcaagacag atctctttgt tcgccgcgat cgtcctttac gtggttttga ttcctacatc
    28141 gttgaaggtt tggtcaagga aatggaaaga acaaacttac cacttcacac tcacaaagtc
    28201 cctgtcaagt tagaaaaaac tactgacggc attaccattc atttcgaaga tggtactagt
    28261 cacacagcta gccaagttat ctgggctaca ggtcgccgtc caaacgttaa gggcttgcaa
    28321 cttgaaaaag ctggagtgac tctgaacgaa cgtggcttta tccaagtgga tgaataccaa
    28381 aatactgttg ttgagggaat ctatgctcta ggtgatgtaa cgggcgagaa agaactgact
    28441 ccagttgcaa tcaaggccgg acgtacccta tctgaacgtc tctttaacgg aaaaactact
    28501 gcaaaaatgg attactcaac tattccaact gttgtctttt cacaccctgc tatcggaact
    28561 gttggtttga cagaagagca agctattaaa gaatacggtc aagaccaaat caaggtttat
    28621 aaatcaagct ttgcatctat gtactctgct tgcactcgca accgtcaaga atcccgtttc
    28681 aaactcataa cagctggttc agaagaaaaa gttgtcggac ttcatggaat tggctacggc
    28741 gttgatgaaa tgattcaggg atttgccgtt gctatcaaaa tgggagcaac caaggctgac
    28801 tttgatgcaa ctgtggcaat tcacccaact gcatctgaag aatttgtaac catgcgttaa
    28861 tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt tttaatgatt ttcgaatcaa
    28921 caaaaaaatt atccaacttg actagtcacg aaaatcggct gttacagttt ttgttacctt
    28981 gtttttaaaa aatggttgac atcgactcct atatgagtat aatagttact atacattaga
    29041 aaagaggtta actattttga aaaaagctca cgtttatgct atccctgcta ttggggctgc
    29101 tctcattgct gctttggcac aaatcagtct tccaattgga cctgttccct tcactctgca
    29161 aaactttgca atcggcttga ttgctactgt ctttagaccg agagaggctg tactttctgc
    29221 tggactctat cttcttctag gtgctatcgg tcttcctgtc tttgcaggag gtggagctgg
    29281 ttttcaggct ttagttggcc ctactgcagg ctatctttgg ttttatctcg tttactctgg
    29341 acttacttcc tctctaacca acagcaagag tggtgttgtt aagatttttc ttgcaaacct
    29401 cttgggtgat gcccttgtct ttgtcggcgg gattctcagc ttgcatttcc tagctggaat
    29461 ggcatttgaa aaagctcttg ctgtgggggt tcttcccttt atcattccag accttggcaa
    29521 acttctggct attagtttta ttagccgtcc cctacttcaa cgccttaaaa atcaggctta
    29581 ctttactaac taaaaaagga tatcgagtta tcatgactca atatcctttt cttttatttt
    29641 gaaaacttat actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca
    29701 aaacactgtt ttgaggttgt ggatgaaact gacgaagtca gtaaccatac atacggcaag
    29761 gcaaagctga cgcggtttga agagattttc gaagagtatt agttgccttt aaaggcatcc
    29821 accatcgttt gaaattcttc atttgagaga gtaatccctt tgcccatttt agtatggtct
    29881 ggactccaag cacgaatatc aaactttgca ggggcaccat taaagctcac acggttaatt
    29941 tccttggtcc aacctttttc gttttcagaa agagtcaaca agtgctcttc gatttcaaat
    30001 gtaaattctg ccattttctt ctcctttttt agtttcatta gtttattcgt aaaatcttgt
    30061 agattttagg aaaattttat ataatattga tataaaagaa gggaggccaa tatgagacat
    30121 aaattccagc aagttctaaa taaaatacat gattttttaa atggatatga ccaacctgac
    30181 cagactgaaa ccaactccct tacagccact attgaagagg ctatccagaa acaaaccgct
    30241 gttcacctta tcttatctga gacaagcttt acaggtgaca tcatcaaata tgatcagcaa
    30301 ggccagcaaa ttatcgtgaa aaatttttcc aaaaatgtga gccggattat ccgtataagc
    30361 gatattcaac gcctgcgatt tgtcccctca actgtccaaa cagcccaaaa aaatagattt
    30421 aagaaagagt gagatgtagt tgcttcatcc cactcttttt cttagcgaat ttgttcaaaa
    30481 tgtaaatgaa ctgcgatatg atctccataa ccacttcttt ccaagtcacg ttgtaaacga
    30541 taggaaatat agtgttctgc aatggtaatg taacctgcgc ccaataaacg atgttcaacc
    30601 atagattgaa tcatactgat agtcgcacgt tccaccttgg cttcttgtaa atccaaaact
    30661 accttcttag tgacttgagc aagattttga cgcaaatcat ctgtcaaaac ataaacagtt
    30721 tgggctgcct tcaagatggc ttggtaaatc ttatctggat taaattcagc aatttcgcca
    30781 ttacgtttga ttacttgcat aggtttctcc tttattcttt gttttctttg atttctgcca
    30841 gcattttttc ttcttctact gtcagttgat aatgttcaag taaatccggt ctgcgctcgt
    30901 aggttttctt taaactctcg tacaatcgcc actgacgaat cttttcatga tggccactca
    30961 tcaatacatc tggcacgacc atgcctcgat aatcataggg acgtgtgtac tgaggatatt
    31021 ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga ctccttgcca atcacttctg
    31081 gaatcaggcg aactgtagca tcaatcatgg tcatagctgc caattctcca ccagtgagga
    31141 catagtcacc tagggaaatc tcatctgtta ccaaggtctt aatgcgctca tcataaccct
    31201 catagtgccc acagataaag attagctctt cctcttgagc caaatcttca gcataagcct
    31261 gatcaaactg ctttccagca ggatcaagga gaataacgcg cggatttttc ttttcaatag
    31321 catcaaagga atcgaaaata ggttgtgctc tgagcaacat gccctgaccg cctccgtagg
    31381 gctcatcatc tacatgacgg gccttttcag cattttctcg aaaattatga tactggatat
    31441 ccaagagccc tttttctcga gcctttccaa cgattgagtg ctccagtgga gaaaacatct
    31501 ctggaaagag ggttaaaata tcaatcttca tagtctaacc cttctaagat ttccacatcg
    31561 acccgtttat ttggaatatc aacattgaga accactggtg ggatataagg taaaagcaaa
    31621 tcacgtttgc cttttcgttt gaccacccag acatcattag cacctggttg caggatttcc
    31681 ttgatggttc caaccaagct atcaccctca tagacttcca aaccgataat ctcgtgatag
    31741 taaaattcac catcgtctag gtcattcaaa tcttcctcag cgaccttgag actgtatccc
    31801 ttgtactttt cgatagtatt gatatggtac atatctttga atttaataat gtcaaagttc
    31861 ttctgtttac ggtggctagc gatggtcact gtttggacaa actgatcttt ttcatcaaac
    31921 aaagccagct cagctccttt tttaaaccgt tcttctgcaa aatccgtcac agacaagact
    31981 cgcatctcac cctgtaatcc ctgcgtatta acgattttcc caacattaaa gtagttcatc
    32041 ttgtctcctg taatctcctt ttttccatct tattctgaca attctcgaat aatagccgca
    32101 attttttccg attctgacca ttgtaaataa tggtgattcc ctcctaaaat gagtttagta
    32161 ttggaagtcc aatattctga ttctctgtac tctttttctc tataagtctg acaaaaaata
    32221 aatacaggga catgagattc tatcgacaaa ttctcaaaat cttcctcagt aatctctcca
    32281 gatatctgaa attctggatc ttgattttcc aactctaagc ctttttcttg cattaattcc
    32341 cagatttttt tattcgtttc aggactaaat gttgcttgag ttaagttctt aaaataaagt
    32401 tcaggaccac actcgtcaat cagcctcatc tgctcttcca tttctggata aggattttct
    32461 gaaaaatcag caaacatgac ttttttagtt gtcggttcaa ttgctactaa agtctgacgc
    32521 ttaattggtt tctcgagtaa tttgcaagct aaaattccac tccaactatg tgcacaaagt
    32581 atatattcag aaatccctaa ttcttcaagt acttcataaa ccgcatctgc aagattatct
    32641 agattttttc cagcttggtc atgaatcgga ctcctacctg tgttcggaaa atcaattgtc
    32701 aaataaccaa ttgtaggagg aggtttttca agtataagtg aaaaattttc ataacttggt
    32761 agcaaacctg ctccgtttag acaaactagc actttctttt gcttttgata agtaacagag
    32821 aggctaccaa tttctgtaga tacttcaaac ctcttcataa agaaatccac tgattctata
    32881 taatgaatta ttaaaaatcc ttatccttta ttttatcacg ttccaaggat tttctcaagt
    32941 tggaggaagg ggacaatatc tctactttcc cttcaataat ccttccaaat tatgtttatg
    33001 ttggtaatta acggctgcgg ttttgtcttt ctcaaagaca gtcttggtaa ggtcaatatg
    33061 attaatagct acgattgcga cggtgtagta aatgatatca gccagttctc tggcaagttc
    33121 ctcgttcgaa tcctatccct tcttttcgac cagagtgcct attcaaaacc tcggctactt
    33181 ctccgacttc ctccactaac ttcataaaga aaacttcatc agtccgagac tgctgttaat
    33241 gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc ttttatagta tattgaaact
    33301 agaatagtac acctttactt ctaaaacatt gttagaaatc gatttgactg tcctgatcga
    33361 tttgtcctgt tcttgtttca ttttactata tcttctattc cacacaaaaa agcgagacat
    33421 ccgtcccgcc cttcttattt ttcgtcaata acgattctta cttttttgta ttcagttggg
    33481 acagagtaga caatcgttct tatcgcagaa atagtgcgac ccttacgacc gattacacga
    33541 cccacatcgc tttgatcaag attcaaatga tattccaaaa attctggtgt atcttcaatc
    33601 ttgatagtta aggcatctgg ttgtgaaatt aagggtttca caatcgcaat aatgagattt
    33661 tcaatcgtat ccatctgtca acctacttta aacttatttt gagaatttag aatcgtggaa
    33721 ttttttcaat acgccttctt ttgaaaggat gttacgtact gtgtctgaag gttgagctcc
    33781 attagccaac catgcaagaa cgcggtcttc tttcaaagtt acttggtttt cagcaacaag
    33841 tgggttgtaa gttccaactg tttcgatgaa acgtccgtca cgtggtgaac gtgaatctgc
    33901 tacgttgata cggtagaaag gttttttctt agaacccata cgagtcaaac ggattttaac
    33961 tgccattttt aaagtctcat ttctttaatt ttttatttcg gtgaaatagc tgagctattt
    34021 agcacatgtt ctattatagc agatttctgg catgtgtcaa gaaaaaaact tgacagacta
    34081 taaatttctt aaagtattta gaaatttgtt agaataggaa ataaatgttt gaaagatact
    34141 atccgtgaat actattttag aaaaatttta taaagaacac caagtcaaac ccttcatatc
    34201 gcctgaacga gatttggata cttggctcct aagtcccaag cccgttccca agcgaaatat
    34261 gaacttatta gcagatgatt cactagcagg agatatcatt ttactatgga gaatccagtt
    34321 tggtactttt accactgaaa catgatttta aaaactccca ttcgaatatg attcaaaatt
    34381 cgcttagaat caatgttttc ccactttttc aaaaaataaa ttttcatcta atttaaataa
    34441 ctttcaatta agtgtgaatt ttgcttaaaa tcattaaaaa acaccccatg gtgtgaacca
    34501 tgaagtgttg taaatgctgt attgtagcta gttcttaacg tttagagaac tggctagctt
    34561 tacgagcttt cttaagatct ggttccctaa atactttgag tacacttatg gcattgatgc
    34621 ccctaaacat ctaaaaactc tggtagaaaa agggtatgct cttgtcgaaa cttcttttga
    34681 ctcacttgac catctaaata ctactatgaa aaagaatatc ctgaagaaga agggagttac
    34741 tggactttct aaaatgaaat cttgcgacct ggatcaagcc cttcatgagc atttttcaga
    34801 agaagaatta gctggtcact ttcatgtcct tctatggact tttttacaat ggcattgcta
    34861 tcacacccaa tacctatcta agcgcctggt tcgtaaactt tattgcagct cttcctctaa
    34921 atttcctaat tgttgaacca attgcccgtt ttatactaag ttcttttcag aaaccattta
    34981 ctggggaaga agttgaaaaa gttgaagatt ttcaagatga tgatgaaatc ccaactatta
    35041 tctaagccag ttctgtaaac tactaatatt tgaaatccac ttccttttag ggtacaatgg
    35101 ttataaatga atttttgaga ggatcagaat gaaaaaacta gcaacccttc ttttactgtc
    35161 tactgtagcc ctagctgggt gtagcagcgt ccaacgcagt ctgcgtggtg atgattatgt
    35221 tgattccagt cttgctgctg aagaaagttc caaagtagct gcccaatctg ccaaggagtt
    35281 aaacgatgct ttaacaaacg aaaacgccaa tttcccacaa ctatctaagg aagttgctga
    35341 agatgaagcc gaagtgattc tccacacaag ccaaggtgat attcgcatta aactcttccc
    35401 taaactcgct cctctagcgg ttgaaaattt cctcactcac gccaaagaag gctactataa
    35461 cggtattacc ttccaccgtg tcatcgatgg ctttatggtc caaactggag atccaaaagg
    35521 ggacggtaca ggtggtcagt ccatctggca tgacaaggat aagactaaag acaaaggaac
    35581 tggtttcaag aacgagatta ctccttattt gtataacatc cgcggtgctc ttgctatggc
    35641 taatactggt caaccaaaca ccaatggcag ccagttcttc atcaaccaaa actctacaga
    35701 tacctcttct aaactcccta caagcaagta tccacagaaa attatcgaag cctacaaaga
    35761 aggtggaaac cctagtctag atggcaaaca cccagtcttt ggtcaagtga ttgacggtat
    35821 ggatgttgtg gataagattg ctaaggccga aaaagatgaa aaagacaagc caactactgc
    35881 tatcacaatc gacagcatcg aagtggtgaa agactacgat tttaaatctt aaaaaccaaa
    35941 aaaatacagt atccacattc ggtactgtat ttcttttact ctcattctta agttaaatta
    36001 ttaaaatccc atatttggtc tatccagcct tcataaaagt ctggctcgtg gcagaccata
    36061 aggatagatc ccctatattc tttgagagcg cgtttgagct catcctttgc atccacatcc
    36121 aaatggttgg tcggctcgtc cagcactaaa acgttgtttt cacgattcat caagagacag
    36181 aaacgaacct tggcttgctc tccccctgat aatacttgaa tctggctttc aatatgtttg
    36241 gttgtcaaac cacaacgggc aagggctgca cggacttctg cttgattaag ggcaggaaag
    36301 gcattccaga cagcttcaag aggagtttgg cgattaccgc cttctacttc ctgctcaaaa
    36361 taaccaagtt ctaaataatc tccacgctcc acttccccag cgattggcga gataatgccc
    36421 aagagactct tcaagagagt tgtttttcca ataccattag caccaataat cgcaaccttt
    36481 tgattgcgtt cgaaggtaag atttaaaggc ttagtaagag gacggtcgta accaatttgc
    36541 aagttcttgg cttggaagat aaagcgccct ggtgtacgag ctggtttgaa atcaaaggat
    36601 ggttttggtt tctcactttg gagttcgata atatccatct tatccaattt cttttgacga
    36661 gacatagcca tattacgagt tgcaacacgg gctttattac gagccacaaa gtccttgagg
    36721 tctgcaatct ctttctgctg gcgttcgtag gctgcctcta gctgagattt cttcatagca
    36781 taaacttctt ggaactggta gtagtcacca gagtaacgcg tcagctgttg attttccaca
    36841 tgatagacaa tattgataac gtcattgagg aatggaatat cgtgcgaaat gagaacaaag
    36901 gcattctcat agttttggag atagcgcttg agccaatcaa tatgctcagc atccaagtag
    36961 ttggtcggct cgtccaacag caaaatatca ggcttttcaa ggagaagttt tgccaaaagc
    37021 accttggttc tttgcccacc tgacaaagaa gttacatccg tatccatgcc aaagtccata
    37081 acaccaagag cacgcgctac ttcgtcaatc ttagcatcca aggtatagaa atcacgactc
    37141 tccagacggt cttgaagttc tcctacttct tccatgagag catcaacatc cgcgccgtct
    37201 tcagccattt tcatatagag gtcattgata cgagcttcag ctttgaaaag ctcatcaaaa
    37261 gccgtacgga gaacatcacg caccgactgt ctttcagcaa ggacagagtg ctgatccaag
    37321 taaccagccg tcacatattt ggaccactca acctttcctt catctggcag cattttacca
    37381 gtcacgatac tcataaaggt tgattttcct tcaccattgg caccgaccag gccgatatgt
    37441 tctcccttga ggagacggaa ggacacatct tcaaaaattg cacggtcacc aaaaccgtga
    37501 ctcagatttt taacttctaa aatactcatt ttaattcctt atcttgtttt tatgtaatcg
    37561 tttataaagg agccaagcca gatagccacc caaagtgttg gtccacaaat catcaatctc
    37621 aaagacgcga ttgaaatcaa agaaaaagtc taagattaat tgcgtacact cgattccaag
    37681 actcacaaga aaactaaaaa gaaggacctt ttttgttttc cgcaaatttg gaaatagata
    37741 aaggagttgg aaaatcagag gaaaaaacaa gaagacattg aggatatttt gtaaaaaaat
    37801 ccaacataat tgtccaatgt cactcacttc gcccagtttc cagagagaat tgaaaggagt
    37861 caaaagaaaa accaggcgtc caagatgctg aatacctgga gttcccactc ccacggtaga
    37921 ttgttcttga ggagtaaagc aaaaacagac aatgcaaatg ctatagaaaa tgactcccca
    37981 gaccaaaata tgattataag tcttcttcat cattaaggat ttaccgctgc gactgccttc
    38041 tggcggtcac gtttcattgt gttaaagcgc aattgtccac aagctgcgtc aatatctgta
    38101 ccatgctctt gacgaaccac acagttgccc ccttttttct taagcgtatc atagaaagcc
    38161 aacacgcgct ctttgggact acggctatat tggtcatgct cactaactgg gttataagga
    38221 atcaagttta cataagacaa tttcttgatg ttcttgagca attcagccaa ttccaaggct
    38281 tgttctacac cgtcattgac ttcattaagc atgatatatt caaaggttac acgacggttt
    38341 gttgtctcaa tgtagtattc aatagcagca aagagttttt caatcggaaa ggcacggtta
    38401 atcttcatga tacttgaacg aagttcattg ttgagtgcgt gaagagacac ggcaagattg
    38461 atctgaaccc cttcatcagc aaagtcacga attttatgag ccaaacctga ggttgaaacc
    38521 gtgatgtgac gagcaccgat agccattcct ttatcatcat tgatagtacg aaagaaattc
    38581 aagacattgt tgtaattatc aaagggctca ccgattccca tgacaacgat atggttgacg
    38641 cgttcatcct gaccacgctc atcaaagtat ttctgaacca gcatgatttg cgctacgatt
    38701 tcaccgttat tgaggtcacg ctgcttctta atcaaaccag aggcacagaa ggtacaaccg
    38761 atattacagc cgacctgagt ggtcacacag acagataaac catagtgttg acacatgagt
    38821 acagtctcaa ttaacatacc gtcaggcaat tcaaagagat atttgactgt accatcagca
    38881 gactcttgca caatacgttg tttcaaggga ttgaccacaa actggtcatt gagcttagca
    38941 atcaaatcct tggaaaggtt ggtcatttct tcaaatgact gcacacgttt acggtagagc
    39001 cattcccaga tttgatctgc acggaatttc ttttctccct gctccaatac ccattcctgc
    39061 atggtttgat gtgccaaact atgaattgag ggtttcattt cttctcctta ttctctactc
    39121 acttctgacg aatgacaaaa tgacgttgtt ccttgtcctc tttctgagaa tgctggtctt
    39181 tctgacgacg tctatttttc ttatctgcat tcgactttcg tttagtttga gtcggtttct
    39241 ttccttttct agaaggtgtt tcttcttccg tcttacgcat tttcttgtca aatgatgctc
    39301 gcttaggggc ttcattttct aagacaaaat aggcacaacc ataactacaa tactctaaaa
    39361 ggtagtcttg taaacgactg attttttcaa gtttttcttc tgttcggtca tccttgtaaa
    39421 aacctcgtag gcgaagctgt tcgttgctcc agtcccccac gatataatca aacttggtta
    39481 atacttctga aaaacgctga ttaaaagtcg tcacatcaaa ggcatccttg atattttcaa
    39541 ccaaggaaaa agctatccct tccgtttcga ccttgtcccc gtgtaaatgg aactccggac
    39601 caggaaactt gttatagttg tataattcag gtgcaatttc ttttcgcata gatatccttt
    39661 ttccacgatt acttaatact ttattctacc ataatttcta gcagttagca cgtttctcat
    39721 aaaaatgaaa aaagtctaac gattttgtca gaccagaatc ttataaccta aaaaagagaa
    39781 gaacaattct tccctccaac tatcattatt tagcagctgc gtacaattca tctactttat
    39841 tccagttgat tactgaaaag aaagctttga tgtagtcagg acgcacgttg cggtatttca
    39901 cgtagtaagc atgttcccaa acgtccaagc ccaagattgg ttttttacct tctgagattg
    39961 gtgtgtcttg gtttgctgtt gaagtcactt caagtttccc ttctttgttg acaaccaacc
    40021 atgcccaacc tgaaccaaaa cgagttgttg ctgctgcagt gaaggctgct tggaattctt
    40081 caaatgaacc aaatgttgca tcgattgctg ctgccagttc tgctgaagga gctgttttct
    40141 cgggagtcat caattcccag aaaagagcgt ggttcaagtg tccgccacca ttgttgataa
    40201 gtgcttgacg gatatcagct gggatagatt ctacatcagc aagcaaggct tcaaggtctt
    40261 caccgatttc agggtgtttt tctaaagctg cattggcatt gttgacataa gtttgatggt
    40321 gtttgtcatg gtgcaaatgc attgtttccg catcgatgta tggttccaaa gcgtcgtatg
    40381 catatggaag ttctggtaag ataatagcca tctgtaatac ctctttttct ttctatatga
    40441 aaatgataac gcaaacattc acttttttca agttttttgc ttatagataa gcaaatcagc
    40501 aagaaaccca cgacaagata atcctgacgc gggttgtagt ttcaacaaat gtcaattgac
    40561 ctgactagca atctgtaaga gtgccttttc aaaaaggaaa cctttttcat aaagacctgt
    40621 cttaatctga tagtctgtct caatcaaata ggaaatagct tgcttcagaa agctcaaaga
    40681 aagtcctctc gaatctctta atgcaaactt gatttgataa ggatttgggt tacgtcccag
    40741 ataactacct aaactacttg caatctgcga ttctgtttgg ccagactccg ccaaaatctt
    40801 cacctgagta aaagtccgaa attgtcccag catgactgca attagtttga tttcatcttc
    40861 cccttgcaag gtcaagtctc tcaccaaatc gcgcgcctga tccatctttt tagtcagaat
    40921 aaactgagtt aaatcaaaaa tattgtcctg caaggtcttg ggaattgcgt taacaatatc
    40981 ctcttcctcg ataacagaat ccgccttata ggactgtaaa aagagaagat ttttctggat
    41041 ttcgctaaat tgaaaccccg acttgatgag gagattttca aaagaatgat tggtaaactg
    41101 cagaccttgt ttctgactcc acttttggaa atactggcgc aattcttgtt cttttacttc
    41161 tactgcatcg aaggccttgg catcacgctt aagtaatttg actaaccgtc ttttgctatc
    41221 cagctttcct tctgcaaaga ttatcaactt ggttgttgga gaaggattgt caaggtattc
    41281 ctcaaatgac ttaagctcat catctgtcaa aaagcgtttc ttagcagtcg tgatatccat
    41341 aaaataatct aatatcacga ttttctcatc cgcaaagaaa ggaaggctga ccaactccag
    41401 ttccacatcc ttgtaaacta cttctttcat atcaaagtag gcaaagttga ggtcagcaga
    41461 atcataccca atctgtttca acacttgact cttcatcact tcaaactgac cctgatctgt
    41521 ccctgtaaat aggctcaggc tcggtaaatt tgataaagtc aacttctgac tttcttcaat
    41581 ggctagcatc gtctctcctt tcttcagatt tttcgattta atttagtcaa tatagcgcaa
    41641 tttcccacgg aaatcttcta agctctcgta gcctttttcc accatgattg ctttcagttc
    41701 attggtaatg cggtcaaaag cactgacgcc ttctttgtga agggtcgttc ccacctgcac
    41761 catacttgct ccacagagga tgtgttcaaa ggcatctcga ccagtcagaa cgccacctgt
    41821 tccgataatt tggatttgag gatttaaacg ttgataaaag gcgtgaacat tggctagagc
    41881 agtcggtttg atgtattctc caccaattcc accaaaacca ttcttaggcc gaataacgac
    41941 agattcgtct tctatataga ggccgtttcc gatagagtta acgcagttga caaacttgag
    42001 cggatatttg ttgaaaatag ctgccgcttg atcaaagtga acaatatcaa aataaggtgg
    42061 caatttaatt ccaagaggtt tggtgaagta agcaaacact tctgccaaaa tccggtctgt
    42121 tgtctcaaaa tcataggcaa tctgaggttt acctggaaca tttggacagg aaagatttag
    42181 ctcagtcaga ccacgaaaat cactctcttg aacttttttc aaaatagtat gggtttcctc
    42241 tggagacatg ccgaccagag ataagaagaa agttcggttc gactcttttt cctgcaaatc
    42301 taaaagataa tccaaataat agtctaagcc attatttggc aagcccatag agttgatgga
    42361 accaagtgga acatcttggt agcgtggctc aggattcccc tgacggaagt ccaaggtcgc
    42421 tgtcttagta acaaaggttc ctgccgctga gtttttgacc tcttctaact cctctatcgt
    42481 catacaagcc acacctgctg cattcatcaa gcaattgtca aactcaaaac cagcaatttg
    42541 tgttttcgtt gataccatga ttctaatcct ccagatttct tttattgcta atattatacc
    42601 ataattttaa ttctaggttt actagattct gtggttctat ctatttattc ggaaaagaaa
    42661 gtctagtaca gaagtcatgc tatgaaaaca gctagtgtat tggaagtttg aacaaggctt
    42721 gggtaacaga cttttgaatg aagtccaagc aacaaggaga aatctcaacc atgagtccat
    42781 tccatgactc tgttgctcta gaaaaccttg caatagtcaa gtgataacga ataaaacttt
    42841 ggattgaaat atccccatga ttatctatta cgaggagaaa tctcaacctt tatcattttt
    42901 aaagaaatat agtaaaatga aacaagaaca ggagaaatcg atcaggacag tcaaattgat
    42961 tgctaacaat gttttagaag ttgaggtgta ctattctagt ttcaatctac tatacatgta
    43021 aatctctact ttcgcaaaat ggattttcag aacagtatcc cagtatagtt aaaaactata
    43081 aaaaagagag gacgttcccc tcttaaaatc ttattttact gcttctttca aagcatctac
    43141 cttatccaaa cgttcccatg gaagatcaat atctgtacgt cccatgtgac cgtaagccga
    43201 tgtttgacgg taaattggac gcttgaggtc cagcatttgg ataatccctg cagggcgaag
    43261 gtcaaagatt tgacgagccg ctttttcaag ttgactttca gctactgttc ctgtaccgaa
    43321 agtatcgata cgaacagaaa caggttgcgc aacaccgata gcataggcca actgcacttc
    43381 tgccttctta gcaaggcctg ctgcaacgat attcttggca atatagcgag ccgcataaga
    43441 ggctgaacga tccaccttag tcgcatcttt accagagaag gcaccaccac catgacgaga
    43501 gtagccacca taagtatcta caataatctt acgaccagtc aaacctgagt ccccttgagg
    43561 accaccgatt acaaaacgac ctgtcggatt gataaagaat tttgtcttat catcaagata
    43621 agaagatgga ataacttctt tgatgacctt gtcaatcaca tcttgatgga tttgttcatt
    43681 agtggcctct ggatcatgct gagtagaaat aacgactgta tctacacgta ccggacggtc
    43741 attttcatcg tactcaactg taacttgtga ttttgcatct ggacggagat agctaatttc
    43801 tccagactta cgaagttctg ccagacgacg aaccaattta tgactgagtg caattggcaa
    43861 tggcatgagc tcttctgttt catctactgc aaatccaaac atgagccctt ggtcacctgc
    43921 tccaatcaag tccagtggat cttgatcagc atttccacga acctccaagg cttcgttaac
    43981 accttgagcg atgtcaggag attgttccac caaagatggg tgtactccca ccgtctcagc
    44041 agaaaatcca tattctgtat tggtataacc aatctctgca atggtatcac gaaccacacg
    44101 gttaatatcc acataggcat ttgtagaaat ttcaccaaaa acgtggacag aaccagtata
    44161 tacagctgtt tcagcagcaa cgtgcgcctc tggatccttt gctaaaatag catccaaaat
    44221 cgcatctgaa atttggtctg caatcttatc cggatgcccc tcagatacag attcagacgt
    44281 gaataattta cgttctgaca taaaaatgtc cccccttaaa aaatattgtt atagagttac
    44341 aaagtactga taggaaaact cttcgtaata aatacctacc atcttatcgg gactatataa
    44401 ctttatcatt ataccatttt taatctcaat ttgcagtctt taatgtagtg tttcggttta
    44461 gatagttcgt tctcataaag caaaaagttg gagctcagta ctccaacaat ttctattaaa
    44521 atgtttgacg tttagcttta cgctctgcac gaccgcgagc gcgattttca gcacgcttgg
    44581 ttttacggcg cttttcatca accgcccatt gaattttctt cttataaccc ggtttgactt
    44641 ttttcttttt ctttttaacc aaaccaatca tttcgatatc aagtttatct tgttttttct
    44701 cacggttggc acgacgatca cggtcatagg tatcttgaaa ttccccgtct ttgaccatct
    44761 taggactaaa cttgattccc aatttctcca actcacggat atccgagtca tcacttggct
    44821 gataaagggt aatagctgta cctggtaggc catttcgtcc agtacgacca acacggtgaa
    44881 caaaaaaaga taagtcttgc ggaatggcat cattgatgac atggctgaca ccttcaatgt
    44941 caatcccacg tgctgccaaa tctgttgcga caatatactc aaaatccaga ttttgcacct
    45001 gattcatgat tcgcttgcgt tcacgagggg caatatcgcc atggattttt gcaaccttca
    45061 agccttgagc agtcagatat gaatgcaatt catcagcacg cgttttagtg ttaacaaaaa
    45121 tcattgccaa atacggctgc atcaactgag tcaactggta aatttgagca ttcttatcat
    45181 gtcccttggt cgaaatcaac caattatcaa tggtgtcaga aataaccgtt ttggtcttaa
    45241 ttttctccat aacaggattg gataagtatt ttttcaagaa tggttgcagt ttttgtggga
    45301 tagtcgctga gaagaccatg aattgcaagt cttttggaag actgccagca atcttatcaa
    45361 cagtttccaa gaatcccata tccaaggtca tatccgcttc atcaacaaca aatgtcttgg
    45421 ctttatgaat agctaaatca ccagatttaa ccaagtcgta gatacggcct ggtgttccaa
    45481 taacaatatg aggctgattg cttgccaatt tctcaatctg gcgagcctta tccgtaccac
    45541 ccacataatt aaccacacga acttcgacat ctgagtgagc tgaaatctga cgcgctactt
    45601 ggtaaatttg agtagccaac tcacgactcg gtgcagtaat cactgcttgt acactatcgc
    45661 tagcttcatc taattgctgg aaaatcggta acaagaaagt atgagtctta cctgaacctg
    45721 tttttgattc tcctactagg tcacgacctg ccaaaacaat aggaatcaac ttgtcttgca
    45781 cctctgttgg agttgtaaat tttaactcct ccaaggcttc tctaatatag tttttaaatt
    45841 gaaatttcgt aaatgacata acatcctcga ttctatctat cttatcaatt ataccatatt
    45901 ttattccatt acagtagtct cacttattta ggctatttcc agtagcttct ctagtaagaa
    45961 aaggctggaa ttttatagtt ccaacctctt ttcagttatt atttccaatt taataccgca
    46021 ttcaagccat agtgatcact cacttgtgga ctcttgttac catcaaatac gacatgtaaa
    46081 ttttccaccg ctaactcttt ggtagtaaag acataatcga ttcgaagggg ttcagtgttc
    46141 cctttccagc catcaatttc aggcggaaca gtatagctac cacttttctc ttgagcaact
    46201 tcaaatgcgt cttgtaagcc taatggacta gctaaaatag cttggtaacc ttcctgacct
    46261 gctgggttgt taaaatctcc agctagtaaa agtggcttgt tcaatttttt caagacagcc
    46321 tcaaatcgtg cccattcttc ttgaaaacct ttatcccacc aagagagatg aacactggca
    46381 actgctagct ccttgccatc gactacagtt tcagctaggg caacacggcg agtatgatag
    46441 tctgttggat catccacatc tgaaaccaaa atttctctgg cttcaatagg tgttttagac
    46501 aaaatagcca caccttcgtg gtagcggtca tagccgatat ggttataggc ccaggtccag
    46561 tagtaatttt tcccttgctc agataacttt tcaaccaaga gtctaacata atggtcttgg
    46621 tgaataggct cagctgctgg caaagcttga taaaggttat taacctccac ctctgacgag
    46681 gtcatctcct gattgatttc ttggaaacaa atcaaatcat agtccttttc aagaatatct
    46741 tcaagcaaaa tctggaattt ttcctctgct tctttctcca tccaactgtg agtattgagt
    46801 gttaaaaatt tcattctttt ctcccaaaat aagaggttgg aatacagctt ccaacctcaa
    46861 gtatattaca attctacttt agcaactgct gttttagctg caagagaacc tgttttttct
    46921 aatttaactg atttaattgc atcaccattt gtgaagacaa ctactgttga agtttcacgt
    46981 cctgctgcac ggatagcatc caagtcagct gtgacaagga gatctcctgc tgcaactttt
    47041 tgtccttcag caacatgaac tgtaaatggt ttaccttcaa gacttactgt gtccaaacca
    47101 atgtgaacca atacttcaag acctgcttcc gtcacaatac caaaagcatg ttttgttggg
    47161 aagatgcttg atacagtacc tgaaactgga gatacaatgt ttccatttgc aggttctact
    47221 gcaaatccat cacccatcat tttttgagca aatactggat cctttacttg ttccaaagca
    47281 acaacttgac cgtctgctac tgagtaaact tcctcagtaa gatctttgaa gtgaacagtg
    47341 ttttgttgtg cttcagtcat ttggcttgga agagtttcag gaatgatttc acctgaatca
    47401 aggatatctt ggatatcaga tttcaaaatg tcagcttttg gaccgtagat agcttgaacc
    47461 ccttgtcctt tcatgacaag acccatagct ccttctgctt tccattgctc tgcatttcct
    47521 actttatctg catctttaac agttacacga agacgagtca tacatgcgtc aacatcaacg
    47581 atgtttacac gtccaccaag aaggttgata atgtttacag cttgagagcc tgctgcaact
    47641 ttcacttcac tgctggtttc ttctgaacct tcagcagttt cgtagtttcc gttgcgccct
    47701 ggagttgcgt agttgaattt ttgaatcatg aagtttgcga taaagtacat gattacagca
    47761 aagagaacag ttacccaaac gaagttaacg atatccatac caataccagc actgattgca
    47821 ataggtgtac gagtcaagaa ctcgattgaa ccgaatgagt gcatacgtag gtttacgacg
    47881 tcagccatag cgaaggcagc accttgaaca agtgagtaaa caagatacat aggtgttgcg
    47941 atgaacatga acatgtattc gattggttca gtaacccctg tcaagaatgt tgcaagagct
    48001 gttgcaatca tcataccttt gtatttatgt ttcttgtcag catcaacatt acggtagata
    48061 gcaacaatca cacccatcaa gataccgaat gaaccgatca tttgtccaac tttgaaacga
    48121 gctggatgta ctgtatctaa caagtgttga tattgactag catcagtacc tttaaggttt
    48181 acaaggtctg ttacccatgc aagccatagt gggtcttgac cgaatacttg agtaccttta
    48241 gctgcaccag ttaaaatgtc ataagtacca ccaagagctg tgtagttcat tgggatagtc
    48301 aacatgtggt gaagaccaaa tggcaagagc aaacgttcca aagtaccata caagaatggt
    48361 gcaagaattg gagcagtttc ttgtgagttg gcaatccaga taccgaagtt attgatacct
    48421 gtttgaacta ctggccagaa agcagcaagt agaattgcag cgattgctga acgaagaata
    48481 actacaaatg gtacgaaacg tttcccgttg aagaatgaaa gtgcatcagg aagtttacgg
    48541 aagttgtagt atttgttgta agcagttgcc cctacaaaac ctgagataat ccctacgaat
    48601 acacccatgt tcaaggctgg agcttcaaga acactgataa agtaatcagc aactttgatt
    48661 gaaccaccaa agaaagtagt taccatagca tctggatttt tcaacatatc gcctgataca
    48721 ccaaagattg taccagtgat acgattaatc aagatgaagg caagaccagc ggcgaaagca
    48781 ccaccagcac gttctttagc ccagcttcct ccaatggcta gggcaaacaa aatgtgaagg
    48841 ttaccgataa tcccccaacc gatttgctca agaattccac ctgtgatgac aagtggtgta
    48901 aaggttgggt taatcatcac gatagactta ccgattgaaa tcatcaaacc agcagccggc
    48961 ataaccgcga taactaccat caaagcctta ccgaattttt gccaaaattc gaaagacaag
    49021 acatttttga atgtatcttt catcattcaa atctccttta tttttattta ggcaaacgtt
    49081 ttacgaaaac gtttgcactt tctatgattt aattatacca ctttaatttt ttttgtaaag
    49141 gcttttataa aaaaattaca cttttttcta aaaaatttct agtgcgccaa atttcaagtt
    49201 caaattagcc atcaagaagt cttctctggg ggacttcttt ggaagctctt ttcttctacg
    49261 catctctttt caaaaactct tgtagcaaaa aaggagattt tacaatctcc tcataaaagc
    49321 agctatttta cctaaatctt caagaatcgg cgcatggata ttcctgatcc caatgaacca
    49381 atgaaaaccc caatcacaaa tagtagggca atcatcaacg gactaaataa atctggacta
    49441 atcatggata gattttgccc taccaacgat ttgttgacag attggtaaac aatttgataa
    49501 acaataaaga ccaaaacaga tggtgcgata gctcccaata aaccgataaa ggctccttct
    49561 aacaagaacg gtccacggat ataactgttt ttagctccga ccaagcgcat gatttgaatt
    49621 tcgcgactgc gggaaataat ggtaatacga atggtatttg aaatcaagaa aactgcgata
    49681 aaaattaaca aagcagcaat ccctagtccc caaacacgga taaatgaagc taacttgaag
    49741 agtctttctg tattggcacc gccatcttga acctcagaga caccttcaat ttttttagca
    49801 tcttcggcta tagtttttac atcatttgga gtgtttgcct ctacaatata ggcatcatag
    49861 agaggattgg catctccttc aaagattttc cagttatctc ccattatctc ggttaatttt
    49921 tcatattgtt cttctttact tgaaaaggta acacttttaa ccgtagacat gttcttcaaa
    49981 gaatcatata ccttgtggta gtcattattt gtaacagttt gaccttcttt ttcaattgtc
    50041 tgactattat cttccacatc ctttcggata taaactacta cacggacatt attttcaata
    50101 tctgtagcta gtttcgctgt attgaaaata acagatgcaa atattgccac caaggtcaaa
    50161 gtaatcatga ctgaactgac agcagctact gtcatccaac catttcgttt caaacttttt
    50221 aaggcttcaa ataaatggcg aaaaaatcta ctaatcatcg tatccatact ctccttttga
    50281 ttcgtcacga acgacacggc cattttcaat ggcaatgaca cggtggcgca aggtatttac
    50341 aatctggcta ttatgagtcg ccatcaaaat agttgttcct tgtaggttaa tccgttccaa
    50401 gagattcata atttcccatg aattatccgg atccagattt cctgttggct catcagctat
    50461 caatactttg ggattattta caattgcacg cgcaatcgca atccgctgtt gctccccacc
    50521 tgagagttca tttgggaaag aacgaacctt atgcttcaat ccaaccaagt ccaaaacttc
    50581 catcactcgt tttttgatat tacggcgatt ttccccgatt acttccatag cgtaagcaat
    50641 attttcatag acagttttct ttggtaacaa tttataatcc tgaaagacaa ccccaacact
    50701 acgacgtaga agcgggacat ctttcttttt gatcttaacc agattaaaac cagcaactga
    50761 taggcttcct ttatcgattt ttacttcacg atacagagaa cgaataaaag ttgacttccc
    50821 tgctcctgaa ggtcctacga tgtaagcaaa ttcccccggt tgaacgctga ccgaaacacc
    50881 gcgtagagca gtcgttccgt tgtcgtattt tttaacgaca tctctcattt caataattga
    50941 catgtgagtt cctttctatc ttagctaatt cgccacttga gataagcatc gataaaacca
    51001 tctaggtccc catccataac cttatctacc tgagcaacct caaagctagt tcggtgatct
    51061 tttaccatag tataaggcgt gaagacataa gaacggattt ggcttcccca agtgatctcc
    51121 tttttctcac ctttgagaga atctacctcc gcagccttct tatcttgctc catttgatag
    51181 agcttagcct gcaacatctt catggcacga tctctatttc catactgggt acgatccact
    51241 gttgattgga caacaattcc agttggaatg tgggttaaac gtacacctgt tgaaacttta
    51301 ttgacgtttt gtccaccggc accacctgaa cggaaggtat ccatcttgat atcatcttca
    51361 cggatttcca cttcaatagt atcatccaat tctggcatca cttctacaga tgtgaaagag
    51421 gtatggcgac gtttggcaga gtcaaatggt gagattcgca ctaagcgatg aacacccatt
    51481 tctgacttga ggagaccata ggcattaggc ccttcaaatg ataaagttac cgacttaata
    51541 ccagcctcat cacctgcttg gtaatccaac acttccactt taaagccttt agcattacca
    51601 taacgagtat acatacgaag caacatatca ccccagtcct gcgcctcagt accaccagaa
    51661 cctggatgga tttccaagat ggcattgttg tggtcataag gttctgacaa gagtagagtc
    51721 atctcgtagc tggtcattat cttatcaagt tcggctaact gcgctaccag ttcatcatgc
    51781 actgactcgt cttcagccaa aaaatccaat aaaatttcga cttcatcctg caactcttcc
    51841 atcttatgga aggtattgta agtgtttttt aattcattta attcttgcga cgttttttgg
    51901 gccgcaatat tatcgttcca aaaatcaggt tctgtcatct tgttttccaa gatggcaatc
    51961 tcttcctcta gcccttcgag gtcaaagaga ccccctgaaa gaagctaatt tttcacgatt
    52021 tgcgtcaatt ttctgacgaa ttactgaaat gtccataaat actccttttt tacattattt
    52081 cattatagca tattttatca tttctttcca tctttt
//
LOCUS       DAVLHB010000009        51987 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLHB010000009 DAVLHB010000000
VERSION     DAVLHB010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.009"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..472)
                     /locus_tag="VXE36_000616"
     CDS             complement(<1..472)
                     /locus_tag="VXE36_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase beta-grasp
                     domain-containing protein"
                     /protein_id="HEV0778970.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGY"
     gene            complement(509..865)
                     /gene="glnR"
                     /locus_tag="VXE36_000617"
     CDS             complement(509..865)
                     /gene="glnR"
                     /locus_tag="VXE36_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0778971.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(942..1469)
                     /locus_tag="VXE36_000618"
     CDS             complement(942..1469)
                     /locus_tag="VXE36_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0778972.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(1605..2801)
                     /locus_tag="VXE36_000619"
     CDS             complement(1605..2801)
                     /locus_tag="VXE36_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0778973.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(2891..7870)
                     /locus_tag="VXE36_000620"
     CDS             complement(2891..7870)
                     /locus_tag="VXE36_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0778974.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAEEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQKPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNTVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            8163..9794
                     /locus_tag="VXE36_000621"
     CDS             8163..9794
                     /locus_tag="VXE36_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0778975.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIGLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(10353..11960)
                     /locus_tag="VXE36_000622"
     CDS             complement(10353..11960)
                     /locus_tag="VXE36_000622"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0778976.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(12350..12937)
                     /locus_tag="VXE36_000623"
     CDS             complement(12350..12937)
                     /locus_tag="VXE36_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0778977.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(13065..13514)
                     /locus_tag="VXE36_000624"
     CDS             complement(13065..13514)
                     /locus_tag="VXE36_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0778978.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(13519..13908)
                     /locus_tag="VXE36_000625"
     CDS             complement(13519..13908)
                     /locus_tag="VXE36_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0778979.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRGGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(13935..14561)
                     /locus_tag="VXE36_000626"
     CDS             complement(13935..14561)
                     /locus_tag="VXE36_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0778980.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(14575..15138)
                     /locus_tag="VXE36_000627"
     CDS             complement(14575..15138)
                     /locus_tag="VXE36_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0778981.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(15303..15537)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(15591..16094)
                     /locus_tag="VXE36_000628"
     CDS             complement(15591..16094)
                     /locus_tag="VXE36_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0778982.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(16287..17117)
                     /locus_tag="VXE36_000629"
     CDS             complement(16287..17117)
                     /locus_tag="VXE36_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0778983.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATIFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(17102..18784)
                     /locus_tag="VXE36_000630"
     CDS             complement(17102..18784)
                     /locus_tag="VXE36_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0778984.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQAAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGCYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(18886..19188)
                     /locus_tag="VXE36_000631"
     CDS             complement(18886..19188)
                     /locus_tag="VXE36_000631"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778985.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKQCFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(19195..19743)
                     /locus_tag="VXE36_000632"
     CDS             complement(19195..19743)
                     /locus_tag="VXE36_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0778986.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGVIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(19758..20606)
                     /locus_tag="VXE36_000633"
     CDS             complement(19758..20606)
                     /locus_tag="VXE36_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0778987.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20795..22144
                     /gene="trkA"
                     /locus_tag="VXE36_000634"
     CDS             20795..22144
                     /gene="trkA"
                     /locus_tag="VXE36_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0778988.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            22148..23587
                     /locus_tag="VXE36_000635"
     CDS             22148..23587
                     /locus_tag="VXE36_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0778989.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLITLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(23712..25391)
                     /locus_tag="VXE36_000636"
     CDS             complement(23712..25391)
                     /locus_tag="VXE36_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0778990.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDISAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWTFPGPLGLLIGTNF
                     QLISFVFLSLILVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGTQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(25460..26872)
                     /gene="lacG"
                     /locus_tag="VXE36_000637"
     CDS             complement(25460..26872)
                     /gene="lacG"
                     /locus_tag="VXE36_000637"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0778991.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(26882..27226)
                     /locus_tag="VXE36_000638"
     CDS             complement(26882..27226)
                     /locus_tag="VXE36_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0778992.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(27394..29280)
                     /locus_tag="VXE36_000639"
     CDS             complement(27394..29280)
                     /locus_tag="VXE36_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0778993.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(29282..30604)
                     /locus_tag="VXE36_000640"
     CDS             complement(29282..30604)
                     /locus_tag="VXE36_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0778994.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            30771..31994
                     /locus_tag="VXE36_000641"
     CDS             30771..31994
                     /locus_tag="VXE36_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0778995.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            32646..32816
                     /locus_tag="VXE36_000642"
     CDS             32646..32816
                     /locus_tag="VXE36_000642"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0778996.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            33428..33712
                     /locus_tag="VXE36_000643"
     CDS             33428..33712
                     /locus_tag="VXE36_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778997.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            33705..33953
                     /locus_tag="VXE36_000644"
     CDS             33705..33953
                     /locus_tag="VXE36_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778998.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            34049..34267
                     /locus_tag="VXE36_000645"
     CDS             34049..34267
                     /locus_tag="VXE36_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0778999.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(34635..36959)
                     /gene="pflB"
                     /locus_tag="VXE36_000646"
     CDS             complement(34635..36959)
                     /gene="pflB"
                     /locus_tag="VXE36_000646"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0779000.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            37308..38369
                     /gene="dinB"
                     /locus_tag="VXE36_000647"
     CDS             37308..38369
                     /gene="dinB"
                     /locus_tag="VXE36_000647"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0779001.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSN
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(38516..39361)
                     /locus_tag="VXE36_000648"
     CDS             complement(38516..39361)
                     /locus_tag="VXE36_000648"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0779002.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            39617..40566
                     /locus_tag="VXE36_000649"
                     /pseudo
     CDS             39617..40566
                     /locus_tag="VXE36_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(40945..42834)
                     /locus_tag="VXE36_000650"
     CDS             complement(40945..42834)
                     /locus_tag="VXE36_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0779003.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAEPADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLQLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINFYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            42972..44537
                     /locus_tag="VXE36_000651"
     CDS             42972..44537
                     /locus_tag="VXE36_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0779004.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            44537..45277
                     /locus_tag="VXE36_000652"
     CDS             44537..45277
                     /locus_tag="VXE36_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0779005.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(45386..45601)
                     /locus_tag="VXE36_000653"
     CDS             complement(45386..45601)
                     /locus_tag="VXE36_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779006.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(46473..47723)
                     /gene="ilvA"
                     /locus_tag="VXE36_000654"
     CDS             complement(46473..47723)
                     /gene="ilvA"
                     /locus_tag="VXE36_000654"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0779007.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(47773..48129)
                     /locus_tag="VXE36_000655"
     CDS             complement(47773..48129)
                     /locus_tag="VXE36_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0779008.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(48367..48603)
                     /locus_tag="VXE36_000656"
     CDS             complement(48367..48603)
                     /locus_tag="VXE36_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779009.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(48710..49732)
                     /gene="ilvC"
                     /locus_tag="VXE36_000657"
     CDS             complement(48710..49732)
                     /gene="ilvC"
                     /locus_tag="VXE36_000657"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0779010.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(49798..50274)
                     /gene="ilvN"
                     /locus_tag="VXE36_000658"
     CDS             complement(49798..50274)
                     /gene="ilvN"
                     /locus_tag="VXE36_000658"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0779011.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(50267..51967)
                     /locus_tag="VXE36_000659"
     CDS             complement(50267..51967)
                     /locus_tag="VXE36_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0779012.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELSEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDILPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
BASE COUNT        15858 a        11274 c         9108 g        15747 t
ORIGIN      
        1 agtagccacc cttgtcattc acttcaagtg ttgggtcccc attttcatcc aacttaaata
       61 ggaagaattc tggctctgga ccaaggttga aggatttgaa tccaacttct tccatgtgac
      121 gaagagctcg tttcaaatta ccacgagggt cacccgcaaa tggttcacct tctgttgtat
      181 agacatcaca gatcagacct gcaacacttc cattttcatc tccccaaggg aagactgtcc
      241 atgtatccaa gtccgggtac aagtacatat ccgactcatt gatacgtaca aaaccttcaa
      301 tagaagatcc atcaaacata accttgttcg acaagacctt atctaactgt tcatctgtag
      361 caggaatttc gacgtttttc atggttccca aaatatctga gaacataaga cgaataaagg
      421 taacattttt ttccttgact tcacgacgaa tatctgcagc tgtgattggc ataagttttc
      481 tccttaatct atgactactt gcggttgcct aaccgcgacc aaaaggtgac tgtactgaag
      541 caaaacgccc ctgttggagg agttcattgt gaagtgcacg acgtacttca gtctgactaa
      601 ccgctttctt ggatttcgct tcacgttcag catatttttt cttaatggca gcgatattat
      661 aaccttcaga gatataatct ttgatttcaa gcagacgatc catgtcattc aaggaataca
      721 tgcgacgatt tccttcgttt cgatcgggct tgatcaactc ttgatcttca taataacgaa
      781 tctgacgcgc cgatagatcg gtcaacttca taacactgcc aataggaaaa acagccatat
      841 ttcggcgaaa ttctttttcc ttcatttaca atttccttct ttctgtctat tatagtctaa
      901 aaaaagacaa acgtcaattg ataatgttat aaaatgtaac attatttttc ttttttctct
      961 aaaaagagac gaatacgatc aatatcgtaa tttacgataa ttgcgacaaa aactcccata
     1021 aacgtttctg atacacgcac aaacacgtac gaaattgtct caccacttgg aattgatagg
     1081 gtaatgatta acatagctgc tacaccacca ataacccctg ctttgttatt catggctaca
     1141 tttgtcataa tggttaacat ggtgcagatt ggaacaacta ccaaggtcac ccaaaaggct
     1201 tcgtggaaaa aggtatttaa taagaagaag accaaggcat agagtccacc gatactattt
     1261 cctagaatac gcgaagtccc aaaatgaaca ctctcatcaa aactctccct caggctaaaa
     1321 acggctgtca aagcaccaat ttgaagacct ttccagccaa aaaagccaaa aatcaagaga
     1381 actagaaaaa cagcaatacc tgttttaaag gttcgcatac caagtttgaa ctgggattta
     1441 tcgaatttat attttttaaa ataactcata atctcaactt tctatttcca ttttatcata
     1501 aatcggtgat ttttatgagt aatagttgag aggaagcgtt tttattttaa gcaaaagaaa
     1561 agaggaactc tcatccctct cttctttgat ttgtttataa aatcttattt ttctgtcaag
     1621 gctgcaagtc ctggaagaac cttaccttca agaagttcca ttgatgctcc accacccgta
     1681 ctaatccatg agaacttgtc tgcacggcca aggttaatcg ctgcggcagc tgagtcacca
     1741 ccaccgatga ttgatttaac tcctggttgt ttcacgatag cgtccatcac accaattgta
     1801 ccagcttgga aatctgggtt ttcaaataca cccataggtc cgttccatac aactgttttg
     1861 gcaccagtca aagcttcgtc aaatttggcg atagattttg gaccgatgtc aagaccaagg
     1921 aagccttcag aaactgcttc accttcagtg tcacgcactt cagtgtaacc agcaaatgcg
     1981 ttagcttctt ttgagtcaac tggcaagatc aatttaccat ttgctttttc aagaagagct
     2041 ttcgcaacat ccaatttgtc ttcttctaca agtgagttac cgatttcgat accttgtgct
     2101 ttgtagaatg tgtaagtcat cccaccaccg ataaggactt tatcagcttt ttcaagcaag
     2161 ttttcgataa caccgatctt gtctgaaact tttgaaccac caaggatagc cacgaatgga
     2221 cgttctggag tttcaactgc ttcttggatg taggcaattt cgttttcaag aaggaaacca
     2281 gcaactgctt tttcaacgtt tgctgagata ccaacattag atgcgtgtgc acggtgagct
     2341 gtaccgaatg catcgtttac gaagatacca tctccaagtg atgcccagta tttaccaagt
     2401 tcaggatcgt ttttagattc tttcttgccg tcaacatctt cgtaacgagt gttttcaacc
     2461 aagagaactt gtccatcttc aagagcgttg attgccgctt ccaattcagc accacgagtg
     2521 acacctggga aaacaacatc ttgaccaagt tttgctgcca agtcagctgc tacaggagca
     2581 agtgatttac cagctttatc agcttcttct ttcacacgtc caaggtgaga gaaaagaatt
     2641 gcacgtccac cttgttcgat gatgtactta atagttggaa gagctgctgt gatacggtta
     2701 tcgttagtga ttacgccatc tttcaatggt acgttgaagt caacacgaac gaggactttt
     2761 ttacctttca agtcaacgtc tttaacagta agttttgcca tgttacaaaa actcctttat
     2821 ttattttatt cgaaactatt atatcacact ttggaaatat aaggaaagat ttcacaagat
     2881 ttttcgatat ttaatcttta tcttctcttt tccgtctcaa ggtcaaggct aaactagcaa
     2941 gaccaaggct ggctaagcct gctattaggg cttcattagc atcagctgtt cctgtatttg
     3001 gcaattgttt gcttgcttct tctgatttaa ctgctgtatt ttgagctggt ttttcctgtg
     3061 tagctactac tgctggtact gtttttactt ttgttccaat ttcaacaatt tctggaatcg
     3121 cttcttggat gacttctgtt gaacgaagac gacgctgacc gttttcatca acttcaaaga
     3181 catgtcttaa cagtccatct cgtccctgta tgatgactcg ttgttcccca actagcatct
     3241 cagtattttc atgctcttga cgatgaaagg caaccttttc ctcttgaact tccaatttag
     3301 gagccttttg ttgatcagaa gtcggttgat aagtaggttt tggaaggact gtgttttgtg
     3361 gtgctggttt agcaggttgt ggtttttcag cagattcata aacaaaggca taatgagtaa
     3421 agtgaggtgc tgtaaagata acatgactat ccgtttgttc aaaagccaat tctactgcct
     3481 ctttgccttc aggtaagaaa aatactttct taactttctt atctttttca attgggattt
     3541 tcacaataga agcataagag agatcaacat cttgaccttt ttcatccaaa ccttctattt
     3601 caaagacatg agcatcttct ccagcaaagt atttcttctc ttcagcactt gcttgaacac
     3661 gctctacttt caaacccttg atgacagtct tctctttatt tgagaagtgt acttcaacac
     3721 ctgttttact atcagaaaag actgctggct tgtcttcttt caataaagca accagatctt
     3781 ttagactctg tttcgctgtt gtaagctctt ctggactcaa atctactttt tcaaccaagg
     3841 ccttgttttt ctcaagaagc ggagctaggg cagaacctga aggatggttt ggtttggcag
     3901 ccaagagttc ttgaacctca cctgttaagc gatcaagctc tgtcttttct tccgtaaatt
     3961 tctcttgacc attcagagct ttatgagctt ctgtcaattt attaagtcgg tcattgactt
     4021 gatcttgggt gctagtttca tggtctttca acacttgttc ggccgcttca attgctttca
     4081 agaaggcttc ttttacttct gatgaagcaa agttatagac caccttgttc ttagcagctt
     4141 caacttctgc taatttttgt ttgaggtact catcgttcaa tgctgctttt ggagatacca
     4201 aaacatcaaa gctaacttca tggccttggt aatgaagcgt caaggtttga cgaccagtct
     4261 tttgagcatc gtaaccagaa atttcaactc cctcatcagt aaaggaatgt tcttccatgg
     4321 tgtcattgct ataagccact gcaaagcgtc cttcagacaa gtctaagcta tcaccaacta
     4381 ggtaatcttt tttcggtttc tgacttactt caattcccaa aatagttttc ggacttgctt
     4441 cgtcttggcc agtgacagtc actgacaaat tagcatttac tggttgtccc aaatattgga
     4501 gagtaagatt ctgttctccc ttatgatgcg tatcaaaacc tgatactgat acacctgcgt
     4561 gagttaggcg aatgagttcg tcctcagttc ctccttcata ctgaactcga agaacaccac
     4621 ctctaaggtc caaatcctcc ccttcggcgt agcttgtttt cttaggtcct gtttctaggc
     4681 tgactgactt gattcttctg tcatcttttg gaacggaaac tgctaggaca ttactaattt
     4741 ccttgcctgg caactgggta cgataataaa gaagaccaga ttgatttgtc aaatccaatg
     4801 gtgcacttgc taggtctcct ccaacttcgc tcttcaaggt tgcaagcgga gtttgagaat
     4861 ttggattatc ataaacggta atagttgctc cagccggtac atctgcaaag ccaacttgta
     4921 ccttgttatt gcctagagaa cgggctgcag ccttggccat cggaatattg acactctcag
     4981 tatcaagctt ttcatacatt ttccagttat agatacgaat agccttccat ggagttccat
     5041 tgtcagaagt gacaacattc aagcgccagt cttgagcagt gattggttta tcaagagtga
     5101 tatctgtcac gtgtgctttg ttaccacgga cttccttagc tagcttccac tcaccatctg
     5161 catctttata ataaaggtca aagtctttgg tgttcatcaa gccatcgtta acagactcac
     5221 caccagcccc tgcatgatcc atgacccatc taacaacggt acgtggcttg gtcaaacgaa
     5281 tatccacact accactcaac tgagctgaag accatttatc tgacaagcta gtaatggtac
     5341 cgttcaacat accttcaata ccttctccac cttcagtctt agggaaagta ctatcaataa
     5401 ctgttgcacc tggaacgata ttttcagcta gtggttttgg taggctggta tcttttacag
     5461 tcatacccca atcaaaggtt gtggttgcag cttctgaacg aactccattt ttaccgactg
     5521 ctacaacctt cagttcttga gttgtaccct gagcacttgc tgagcggcta acttttggta
     5581 gataaatagt tgtagaagat gagccagtta gtaatttcca gctgtctcca tctttttcat
     5641 aaacttcata gaaatctgca tccttgttgc ctttaaattg cacaactgct tccgcttctt
     5701 gggcattttt aagagattgt ttcactacag aaaagcttgt cggcgattgt ggctcttggt
     5761 gattgtccga gatagttaat tgtccgaggt tgaactgata atcttttaca gcaccttcat
     5821 gctcgaaaaa tagtttgact gcatagatgg ttttacctgc tagtgagctg agatcaaatt
     5881 cttcatttgt ccagttgtca gaaagggtta gctctttcca tgcatctgca tcatcgaatt
     5941 tgtagtctgg agttgtagag aatgccatat aaactttaga accttttcct cccttgtggg
     6001 caacacgaag tttggtcttc tcagttactt ctaacttagt agaataaagt ctcacatcct
     6061 gatctgtctt accggctaca tcaccagaga atttaaggga atttccgcca ttataggcat
     6121 ctgtaaaatc atattctgca cgaagttttt cccctgttga agtctgccac cagcgccatg
     6181 ttggaagaac acctgatact gaacgataat tccactcaga atccttagaa accttaccat
     6241 ctacgaacca ttttttacca tgacctgtat taaaagaagt agtaaaagta ttacctaccg
     6301 ctggcgtacg gtccgcaact aggttagcaa taccatacca atctttgtca cctggttttt
     6361 ggccagtagg gtctccttga taacctgtaa agaagatatc ttcattttta tgataatctt
     6421 caccagtttt tcctaaactt gtaatggtat ctggggcaaa taaaccaaga gaaaggcgca
     6481 atttcccatt ttcgtctaaa atgtcattcc acttaacctt tgtcttgtag gaaccaccct
     6541 gttgcaattc caaacctgca aatacatcat aaggattacg accaatccag ttggcagttg
     6601 caatagtgta atcattttta gccttatccc agttaaagtt agcaaagaag ttatctgccg
     6661 gaaccttatc tccttctggt tgcatgaatt ggtagttgta ttctcccaaa ccatcttgat
     6721 ggtaacgtcc atagttatag gtcatggcat cataccaaga atacttgatt ggatggttta
     6781 ccttggcagc atattccttg ctatagagca taaactggcg catcttttct ccaagaggtt
     6841 taaccaaatc tccagttgtt tcttggttga tgaaatagcc atcatagcca taatactttg
     6901 ccatgtctac caatttacgg gcaattggga agctaccatc tgcgtcttgc ttcaaagctt
     6961 cagcaaatct ttcttgatct gcaatactat tagaccagtt gaagaagagt gtaccgtata
     7021 caggaacccc gttacggtga cctgcatcaa taacgtcagg agttggtacg agaccttccc
     7081 agaagaccat tgaatctaga tattgccaat agtcaaaagc ataggccttg aactcttctc
     7141 caccaacaga agcatggtct tttgctttag aattggtgtt tgataaggct tgaacttttg
     7201 cttccttgct agctttttca ttgactaaat gacctgtccg acgtgaagcg aggacaacag
     7261 atccgcggtt aatagcatca tcttcacgag cacctggttc ccattttaac aattcttccc
     7321 aagaattaaa tttgatttcc tttggtttta atgttttttc tgtattttta gggacatctg
     7381 gctggacttc tttttcagtc ttattagctt cttctgctgg tttagactca tccccttggt
     7441 tagttgcttc gggctttgct tctgtttcct tgtcagactt aggttttgct tctgcagatg
     7501 gtgtttctgc aaccacctca cttgcttttt cctctggttt agctgcgcta gctgcttctg
     7561 cagtttcagt agttgcagct tcattgcttg ctggcgaagc agtttcagat gctgtcgcta
     7621 ctccttctgc cttttctagc ttgttttctc tagcatgttc cccttcattc tgcttatcag
     7681 cttcattggt cgaatgctca ctctctcctg aaacaagctc tgtattagct ccgctatttt
     7741 caggaactgc agtttcttca gccaaggctg gaccaacaaa taaaacagca ccaatcatca
     7801 gcgagcaggc tcctactgat aacttacgaa tactgtaacg acaacgtctt tcaaaaaatg
     7861 gattcttcat tttctcctcc taaaagattg attttgttgt tttcaagaaa gcgctttata
     7921 ttctgtagtt ttttatcaaa ctctagaacc atgataatca catttttatc ctaaaacatt
     7981 tttagacaaa aaacaatagc tgttttcaca aatctaaaat aaggttaaaa actcttaaaa
     8041 ataatacact tatcaattat aattttcttt tacaaacttg acattaacac ttgttagatt
     8101 tacttttatc ctttaaaata gaataggaga tattccgcga ttatttttcg gaggaaaaag
     8161 aaatgtccat taattggcag gaaattttat ttcacttttt aggtggtctg gggctattct
     8221 tatatagtat caagaccatg ggagacggtt tgcaacaagc tgctggagat cgccttcgtt
     8281 tttacattga caaatatact agtaatcctt tctttggagt tctggttggt attgggatga
     8341 ctgctctaat tcagtctagt tctggtgtaa cagttatcac agtcggcctg gtcagtgccg
     8401 gtctcttaac cttacgtcag gctatcggga ttgtcatggg tgctaatatt gggacaactg
     8461 tcacatcctt tctcatcggt tttaaattag gtaactatgc cctacctatg ctctttatcg
     8521 gtgccgtctg tctctttttt acaaaaaatc ggacagtcaa taatatcgga cgcatcctct
     8581 ttggtatcgg tggtatcttt tttgccctca atctcatgag cggcgcaatg gctccactca
     8641 aggatttaca ggtctttaag gactatatga ttgagctaag taagaatcct gttttgggtg
     8701 tctttgtcgg tactggcttg accttgctaa ttcaagcttc ttcggctacc attgggattt
     8761 tacaaaacct ctacgccggc aatctaattg acctacaggg agctttgcca gttctatttg
     8821 gtgacaatat cgggacaacc attacagcca tcattgcctc tttaggggct aatattgcag
     8881 ctaaacgggt agcaggagct catgttgcct tcaacgttat cggaacagtc gtctgcgtta
     8941 tttttctagt tccttttact gtcctgattc attggtttga agctacgcta aatctagcac
     9001 cggaaatgac catcgccttt gctcacggaa cctttaatat taccaacacc attgtccaat
     9061 ttccatttat cggagctctg gcttactttg taaccaagat tattcctgga gaggacgagg
     9121 ttgtcaaata cgaaccctta tatcttgatg aacatttcat caaacaggcc ccatctatcg
     9181 ctctaggaaa tgctaagaaa gagctcttgc acttaggaaa ctacgctgct aaagcctttg
     9241 acctttccta taagtacatc attggcttgg atgaaaaagt tgctgaaaaa gggcataaaa
     9301 ccgaagaagc aattaacacc atcgatgagc aattaacacg ttatctcatt gccctttcaa
     9361 gcgaagctct cagccaaaaa gaaagtgaag tgcttaccaa tatccttgat tcctcccgtg
     9421 atttggaacg gattggagac cacacggagg ctctactcaa tctgactgac tatcttcaac
     9481 ggaaaaatgt tgaattttct gatgccgcct tgaaagaatt agaggaagtt taccgccaaa
     9541 ctagtgactt tatcaaagat gctctggata gtgtggaaaa caatgatatt gaaaaagcac
     9601 gcagtcttgt agaacgtcat gaagcaatca ataagataga acgtgttctc agaaaaaccc
     9661 acatcaaacg cctcaacaaa ggcgaatgtt caacacaagc tggagtcaac tttatcgaca
     9721 tcatctcaca ctacactcgt gtatcagacc acgctatgaa ccttgctgaa aaggtttttg
     9781 cagaacaaat ctaataacca agaagctatc catcataatt ggatggcttc ttactttttc
     9841 ctaagcaaga ctaggctgaa tgaaactgaa agagtattct gcagatatat aatatattga
     9901 aactagaata gtacacctct atttctaaaa cattgttaga aatcgatttg actgtcctga
     9961 acgatttgtc ctgttattat ttcattttat tatagtggat taaattaaaa aagtatagta
    10021 tattgaatct ataacagtcc atcttgactg ctaaaatatt tctataaatt aatttgactt
    10081 tcctgataga gatgttcaca tcttatttca attcactata caatccagtt cctaaaactt
    10141 tgctagaaat tgatttggct ttccgaatta atttgttcaa attttatttc atttcaatat
    10201 actgataaat ccattcacta gcacagggca agagggagtc gctattgatt tcaacggtag
    10261 caggtacata cagaggactc ctacctcaga tatactgcaa tatcatcgta tgcaaaaaac
    10321 ctctgagatt tttctcaaag gttctgattt tgctaattgc tgttctcaac cgctgcagta
    10381 acaaaggcag tgtagagttc ttctggtcgg tttggacggc ttgacagttc agggtgatac
    10441 tgacaagcta caaagaattt attttcagga atttccacga tttctaccaa acgattgtct
    10501 ggagaaactc ctgaaaagac aaaacctgct gcctcaaact gctcacggaa ggcattatta
    10561 aactcataac ggtgacggtg acggcgttgc accacttctt gattgtgata agcagcagca
    10621 gccttagagc cacgtttcaa cttagacgga taaagtccca aacgaagggt tccacccata
    10681 tcctcaatat caatctgatc acgcatgata tcaatgatag ggtattttgt ttctggtgca
    10741 agctctgcag aattggcacc ttcaagacct aaaacgtgac gagcaaactc gatacatgtc
    10801 aactgcattc ccaagcagac tcccaacatt ggaacatcat tttcacgcgc atagcggatg
    10861 gcttggattt tcccttctgt accacgttga ccaaaaccac ctggtacgat gatcccgtcc
    10921 gcatcagaca agagttctgc tacattctct gctgtcacat cattggcatt gacccaattg
    10981 attttaactt ctacatcatt gacatagcca gagtgtttca aggcttcgac cactgagata
    11041 taggcatctt gcaactccac atacttacca acaagggaaa tcttaacttg tttcttgagg
    11101 ttcatgacct tgtccaccat ggctgaccat tctgtcatat ccgctgctgg tgcgtctaat
    11161 ttcaaatgat cacaaacaat ttggtccatc ccttgtgcct gcaagttcag tggaatttgg
    11221 taaaggtgtt caacatccaa cgattcgata acggcttctg gtgccacatc acagaactgg
    11281 gccagtttat ttttaattcc ttgaccagct ggctcttctg tacgaataac caacatattt
    11341 ggttggattc ccaagccacg caattctttg acagagtgtt gggttggttt ggttttcatt
    11401 tcaccagcag ccttgaggta aggaagcaag gttgtatgga tatacatgac attatccgca
    11461 cccacatctg ccttcatctg acgaagagcc tctaggaatg gcaaggactc gatatctcct
    11521 actgttccac caacctctgt gataatgaca tcagagtcgg tcgttagagc ggcacgcttg
    11581 attttttctt tcaaagcatc tgtgatatga ggaatgactt gaacagttgc cccaaggtat
    11641 tctccacggc gttctttacg aagaacttca ctgtaaattt tcccagttgt cacgttggaa
    11701 tatttgttga gattgatatc gatgaaacgt tcatagtgac ccaagtccaa atctgtctca
    11761 gctccgtcat ctgtcacaaa aacttccccg tgctggtaag gactcatggt tcccggatca
    11821 atattgatat aagggtcaaa cttttgaatg gttactttga gaccacgatt tttcaagaga
    11881 cggcctagac tcgctgccac aatccctttc ccaatggacg ataccacacc accagttaca
    11941 aaaatatatt tcgtagacat agattcctct ttctaaaatg ctcaaggtct tgttaactac
    12001 gaggggatat agaaaacaag accctactaa taagaataat ctgggacgac tgcaccagat
    12061 tcacaactaa tactcttcga aaatctcttc aaaccgcgtc aacgtcgcct tgccgtagat
    12121 atgtgttcct gactttgtca gtcttatcta caacctcaaa acagtgtttt gagcagccta
    12181 cggctagttt cctagcttgc tctttgattt tcattgagta taaaatacaa gaagataact
    12241 tcttgaaaaa acaaaaatag ctccctaaga actagggagc cccgacctct aaaagaggtg
    12301 cccaaacaat atgataccta aaaataggat aattgtcaat agctaactct tattcctcgc
    12361 tggtttcagc gtcgtcatct gaaaactcgt cgtcgtcttc gttgagatcc acatcttctc
    12421 ccaagtcatc tggagcgatt tcgttgattt ctgcatcata agcttccact tcattttttt
    12481 catcatctgg attttcatca tcgtatgaaa gagctggatc tgcttcgtat gcatcttcgt
    12541 cttctggatc atctgcattg tagtcaatgg catctgaatc accatccata aaggcattga
    12601 cacgtttttt cttagctttt ggtgctactt catcgtcgtc attttcttca agagcgatga
    12661 tttcttcgtc gatttcgtcc acaccatacc atgaacgaag accccatttg ttgtccccaa
    12721 gtgagatgaa gctaccgtca aagttcaact ctgtgtagaa caaaggcaaa gcttcgcgga
    12781 tatcgctgtt tgatgttcca aggtagtttt gaatttcgtt tacaagatcg ctaaaatgca
    12841 tctcatgatc gcgaccacga agttccaaga tagcacgcgc tacctcaatc atagatagtt
    12901 cacttttttc ttgcccagca aatacttcta attccaaagc gtttctcctc atttatacta
    12961 ctattgtcag agcgaacaga ctctgacctc attttatcat ttactcttta ttttacgata
    13021 attttgcgga atagtcaaag gttaaggggg agaaagtggc aggattagac taattccaat
    13081 ataaaactcc ttcctttttc tgttgctcca ttttccacaa atccaagcga cttgaaacac
    13141 ctcctagaag catgattgta ggtgtagatt tccttgactc tcaattcttt ccatcctttt
    13201 actcgagcca attcaatcaa agcacttaga atcttttttc caagtcctcg atgttggtaa
    13261 gcggaattcc caatcacaat ggggagatta tcctgagata gtgtaatatc cccaattgga
    13321 aaccattctc ccttctcctt gacttcaatc caaaaaagct caccatgccg atccaaatag
    13381 gaatacatgg cttccaaggt cgcttgactg taaggaagct tcaccccatc tacgaggtaa
    13441 accaagttca catcctgata ccaagcaaaa gcttcctcac aataattgac cttataataa
    13501 ggaacaaaac acaatgcact accttttcaa caaaagagtt gctgcttgat taaaaccatc
    13561 acaccagtta taccattttg cttcataccc atcttgagct aggatacgat cttctaaatc
    13621 aaaaacagag taaatctttc tttcctcgca agcttgcgca tagagatgat atagttcatc
    13681 accaccacct ctatcccact cagcagaaat cgtatcccga cctgccaata aagcctgata
    13741 agccctgtga tgcccatctg taatcagcaa acaatctcca aaggcaagaa tactgattgg
    13801 atcgacttgg attgtttctg ccgactggta aagcatctga atatcttgca acttcttttc
    13861 tgataaatat agttgagtcg gatgaagatc tgctatattg actttcattt ctttctctca
    13921 agggaattcg atactcactt ctgtttgcct ttaaatcgcc attggaagcg gagcttgtca
    13981 taaaagggaa actcgataaa caggactccc aagcccacac agagactggc aaggacgtct
    14041 gatgggtaat gaactcccag atagactctt gataccagca cactgactag gtagaggcca
    14101 aggacgattt gtacgatttt tctccagacc tgatctttaa tccgctgact aagaataaca
    14161 atcaaagtcc ctaccatcag cgttacagct agagaatgcc cacttgggaa ggaaaatccc
    14221 ttctcctcca ccagatgtaa aatagctggt cgtgggcgct ggtagatatt tttaaaggtc
    14281 acgattaaaa gacctgccaa agccagattt cccagcatga agaaactttc tatcttccat
    14341 cgcttacgat aaaagacaaa agctataatg acaacccaag tgataatcac tggaatatca
    14401 atcagacgtg tgagggatcg aaaaagaata gtcaaataat ctggtaagtc tcctcgaatg
    14461 gcagtctgaa tcgattggtc aaaattgacc agcgtttcag ggtaaaattt gaccatgtag
    14521 ccaagaataa cgaaaagtaa aagggcaaaa ctgcccttca ttaaaaatgt ttgtttatct
    14581 ctcataatgt tttaaggttg gtttcaagag aacatacaac aaccagaatg aaacggaaaa
    14641 gataacacct tcaatcaagt taaaaggtaa taccatggtc attaggtagt tggaaagtcc
    14701 caaaattttt ccaatatcaa agttagcaaa cttagcgtac aaaggaacag cataaacata
    14761 gttgagaacc aacatggcca aggttaaacc aatagttcca gctagagagc ctagtaggaa
    14821 acgaagggtt gtccgttcct ttttccaaat caaagcaaat acgatgacaa aaactcccaa
    14881 agctacgata ttcatcggca aaccaatgta agtattcact ccttggctgt taagaagcaa
    14941 tttcaagagt gagcgaagca agagcactcc tagagcagca ggcaaatcca tgaccaccag
    15001 acccacaagg actggcaaga tactaaattc gatcttgagg aaagatgccg ctggtaaaag
    15061 cggaaagtca aagtacatca gcacaaatga gatggctgat agaattgcaa tggtcgaaag
    15121 tcgacgtgtg tttgtcataa caggttcctc caattttcta taaaatcaga agaagttgga
    15181 aaggattcct ctatctattc tcacttttta tatcccaaaa gttccctctt actctattaa
    15241 agaaaaacaa agcaagtggt tacaatccgg ctataaatct atcaaaacag acaaggctat
    15301 tctttcgtct tctcccatcc agactatact gtcggttgtg gaatctcacc acatcagctt
    15361 gcgctcacgg acttctttaa agagaaggaa atagagattt ttcttttaga ctaggcgaca
    15421 agctgtaggc ataacttctg gttaggcaaa gcttgtcaac aaagtataaa aggaaaagat
    15481 catttcctag ttaaagtcac cgccggtcgg gaatttcacc ctgccctgaa gactctttta
    15541 tcataacaaa aaacgcttgc aagcgcaagc attttgttca ttttcatttt ttatttcaat
    15601 ttatccactt cataggtatg gacgagctca agacctgcaa agttctgctg gcgaagagcc
    15661 tcatagacaa tcatgcagac ggtattagac acattgagac tgcggacatg ttcatcattc
    15721 atgggaatac ggagagcctt ctcaggatgt tctcgcataa aatcttcagg taagcccttg
    15781 tcttcacgtc caaagagaaa ataatggtcc tcgtcagtcg ataaatccac ctcagaatag
    15841 actttttccg cgaatttcga aatcagatag agttttccct tcatctgaga tatgaaatct
    15901 tccaaactct cgtaaaaata aatctctagc ttatcccagt aatccaatcc agcccgcttc
    15961 atcttgcggt catcaatagg aaagcccata ggcttgatga tgtggagggg agaattggtc
    16021 gcagcgcaag tacgcgcgat attgcccgta ttttgtggaa tttgaggttc aaataataca
    16081 atgtgatttg tcatgacttg cttcctttca ccattgcaaa aaaatagcca cactgcccgg
    16141 agtcaagctc agcaaacagc gtggttaagg catcgttaac ttacctcaca acaggtttga
    16201 agtaaatcag cgaaactact ttcttagtat aacactttca gaatcattgt caatagaaat
    16261 gacttgattt tttcaatttt ttcaagctat ttccaagggt tgtaaaatcg tccctgattc
    16321 tgcaagataa gtagtaaact aactactaaa aacaaggttg ccaagagcaa ggtaatatag
    16381 tctccttttt tcaaggcctg ataactatac catgtgcgtt ttttctcttt cccaaagcgg
    16441 cgaagctcca tggcagtcgc aatggtatca atgcgttcta gcgagctaaa aatcaagggc
    16501 gtaataatga gcagattgcc tttgattcgt tgcataagag aagctttctt ggataattcc
    16561 atcccacgcg cctcctgaga catcttgata gtaaagaatt cttcctgcaa atctggaata
    16621 tagcgcaagg tcaggctgac agaataagca atcttatagg gcacaccaat ttgatttaaa
    16681 ctggaagcaa actgactagg atgggttgtc atcaaaaaga taatagccag aggaatggtg
    16741 caaagatact taatggccaa atttagcaga taaaagagct cctggctggt tagagtgtag
    16801 acaccgattc cctgccaaat cacacttctc tctccataaa gtccaacccc atactcggga
    16861 gaaaagagat agaccatcaa aacgtttaaa acggcaaata tcgtcgcaaa aacggctaca
    16921 aaggaaacat ctttaaagcg aatttctgat aaatagagga gaaagactga aaagatggca
    16981 atcagcaaga gcattctggt atcatagcta atcatggccg ccaatgatac cagaatgaaa
    17041 aagagaagtt tcccagctcc tgacaagcga tgaatcacag tatctctatg ctggtaaccg
    17101 attaatttag cttgcatccc tctctccttt ctttgtaaaa tgccgttaaa tccagtggat
    17161 ccacatctag tttcttagcc aagttaaaga tggaggtttc ttttagattg gcttttacta
    17221 acagctcagg atcgctcaac agactggctg gaacagtatc ggcaatcaat tctccatcca
    17281 ccatgacaag gacccggtct gaataatcca gcatcaattg catatcatgg gtaatcatga
    17341 caatggtatg ccctttttga tgtaactctt cgagaaattc cataatctca gtatagttct
    17401 tctgatcttg acctgcagtc ggttcatcta ggagaataat ttcagctcct aagaccaaaa
    17461 ttgaagcaat ggtgacacgt tttttctgac caaatgacag ggcagaaata ggccaattac
    17521 ggaattcata aagtccacag attttcaagg tttcatatac tctcgtttca atttccttct
    17581 catccacacc tcgcaaacgg agccctagag ccacctcatc aaaaatcata ttggttgaaa
    17641 tcatttgatt aggattttgt agcacatagc ctactcgttc cgcccgctct gcaacagaat
    17701 cgccttttat atcctgtttt tcccaaagat agcatccttc cgtctgaata aagctactta
    17761 tagccttggc tagagttgat ttccctgctc cattttttcc gacaatagca atcttttcac
    17821 cctttttaat atctaaatgt agggatttta aaatcggtct atcatcataa gagaaagaca
    17881 cgtcctctaa tttaaagagt gactgcaatt ctggagtttc ttttgccagt tcattctgca
    17941 gctgaacctg accttttgag atagacatgt tatccagatt cgctaactgt tcttccttga
    18001 ctaagtccac acctaattga cggagagtcg ttagataaag gggttctcga attccatttt
    18061 gagtcaataa atcagtcgca agcaactggt cagggctccc attaaaaagg atacgaccat
    18121 cgtttatcaa gacaatccga tccacagggc gatgcagaac gtcctccaaa cggtgctcga
    18181 taataagagt cgtcgtcccc tcttccttat gaatctggtc aatcaattcg ataatatcct
    18241 gacctgactt gggatctaga ttggcgagtg gctcatcaaa caagagaatc ggactttcat
    18301 caatcaagac accagccaga ctgactcgct gcttttgtcc acctgacaaa tcctgaggac
    18361 gctgatccag taaaggaaga aggtccagct tttcagccca tttataaaca cgacctttca
    18421 tctcatctaa ggctgtcaca tcattttcca gagcaaacgc caaatcttct gccacagaca
    18481 agccaataaa ctgcccatct gtatcctgca aaactgtgct aaccagatga gacttatcat
    18541 agatgctcat atcaaaggct gcttgaccct ttatcaaaaa ttctccatat gtctgaccct
    18601 tgtaaatatt gggaataatc ccattcaaac actgacccaa ggtagattta cctgacccag
    18661 atggtccaac aattaagact ttttctccct tgtaaatggt caagtctatc ccttgcaagg
    18721 tcggttcttg ttgtgtttca taccggaaag agaaatcctt ccactcaatt atagcttctt
    18781 tcatcttact ctcttcattc gcttcttaga cttctatttt atcataaatc aagcccttct
    18841 tgcagtctct tctcttaaaa tcttagcgcc aaaaagattc ctatcttagc ttacttgcct
    18901 aactaatcta taaacatcga aaaagactag ttgcccagcc ttccccatca ttttatactc
    18961 ttcgaaaatc tcttcaaacc acgtcagctt cgccttgccg taggtatggt tactgacttc
    19021 gtcagtttca tctacaacct caaaaccatg ttttgagctg acttcgtcag tttcatctac
    19081 aacctcaaaa cactgttttg agctgacttc gtcagttcta tccacaatct caaaacactg
    19141 ttttgagcaa cctgcggcta acttcctagt ttgctctttg attttcattg agtattagtc
    19201 ctttttcaaa cttcctgcac gagtttgggt tcctgcatag gcaagtaaga gaagagttcc
    19261 tgcaatagct acagatacac cattggcaat tcccgcaaca atcccttgtg caaatacttt
    19321 ttctgccgct tcttgataaa tcacaacatc tccaagtggt gccaagacac cccaaacaag
    19381 ggcatttgca agtagttgaa tgaggttaaa aataagaata tctttccagt caaaaacacc
    19441 attgatcact cgaacgtact ttctaaaaag tcccacaact aaaccaaaga gtccgctagc
    19501 gataatccaa gtccaccata gaccataacc agcaagagag tccttgattg catgaccaat
    19561 caccccgaca agcaaaccga taatcggtcc aaaaataata gaaagtagcg cttgtaccgc
    19621 atactgaagc tggatgcttg tatttggaac aggggttgga atgttgatca tcccgatgac
    19681 gacaaagagg gcagcgccaa ttccgacagc aacaacttgt ttaattgtaa atttaatttc
    19741 catactattc tcctatttta tccttctatt ttctttattt caatggtcca agatgaaccg
    19801 acacctacat tataggcctt ggcaaaggaa ccttggttga tagccaaacc taaacgatag
    19861 agagagttga tgtaaaggat gggttgccca attctcacat ctgcaaatga tttgccatag
    19921 acaacctgat tttgatagac cagcatatca gcatgataga tggtcacttc aaaacgatca
    19981 ccaaattctg gttccaactt gtaaaattct tcccgtgtga tagaggtcca aagcgaaccg
    20041 aaacgcacat ccagaatatc aatggctccc ttcaccagat gatcttctat gatggtcgct
    20101 acgactggaa gctctacaat ctgttccaca ctgagctctg gccctacttc ctcaaaagta
    20161 atgtgaccac tggccagttt agcaccagta taggcataga catcacgacc gtggaaggta
    20221 taagaatgct ctgtgttttg acgcctattg gccacctcag aaatctcacg aatggctaca
    20281 atgccaacgt gtttcttgat aaaggaaagc gtcccattat ctggcgtgac aatgtattga
    20341 ttttttgcag tcttggcaac tacactctta cgtttcgaac cgacacctgg atcgacaacc
    20401 gatacaaacg tcgttccctc aggccagtaa tccaccgtct gaaagagacg atagctcccc
    20461 tcaaaaatat tataaggcgt gatatcgtgc gtcaagtgat ggatttttaa ggttggagac
    20521 tcttctaaag ccactccaat catagccgat accgcaccat caaccagacc aaagtctgat
    20581 tgtaatacca gtaaattatt attcatttta tctccttgta tatcctttat cataccatat
    20641 ttcagagaaa gtcgctaata gctatttcaa ttggttaggg tatagtttta ccttatagca
    20701 aatttcctac taaaagttct tgttattagc tagtaggtgc attttttctt gaaaaaaggt
    20761 atgatagtta catcatgaaa aagtaggttt tattatgaaa attatccttg tcggaggggg
    20821 aaaagttggt tttgccctct gtcgctcctt ggttgcagaa aagcatgatg ttttgctgat
    20881 tgagcaagac gaagctgttc tcaatcatat tgtcagtcgc tttgatatca ttggtatcct
    20941 tggtaacggg gccgattttg ccattcttga gcaagccagc gtccaagatt gtgatatctt
    21001 tatcgccctg actgagcacg atgaagtcaa catgattgca gcagttctag ccaagaaaat
    21061 gggagctaaa gaaactatcg ttcgggtgcg gaaccctgaa tattctaact cttatttcaa
    21121 ggaaaagaat attctcggtt tttctcttat cgttaatcct gagctcttgg ctgcccgcgc
    21181 tatcgcgaat atcattgact tccccaacgc cctgtctgtc gaacgctttg ctggtggacg
    21241 cgttagcctc atggaatttg tcgtcaagtc caccagcggt ctttgccaaa tgcccatttc
    21301 tgattttcgt aaaaaatttg gtaatgtcat tgtctgtgcg atagagaggg atcatcaaat
    21361 tatcattcca agcggtgaca tgactgtaca ggataaagat agaatctttg tcactggtaa
    21421 ccgtgtcgat atgatactct tccataatta ttttaaatca cgcgccgtga agagccttct
    21481 catcgttggg gcaggtagaa ttgcctatta tctacttggt attctcaaag atagtcgtat
    21541 cgatacaaaa gtcattgaaa tcaatcctga aatcgccagc ttctttagcg agaaattccc
    21601 aaatctctac atcgttcaag gagatggaac cgcaaaagat atcctgctgg aagaaagtgc
    21661 tcaacactat gatgccgttg cgactctaac aggtgtcgat gaggaaaatc tgattacatc
    21721 tatgttcctt gacagggtag gtgtacagaa aaatattact aaggtcaatc gtaccagtct
    21781 cctcgagatt atcaatgcgc ctgatttttc aagtatcatc acacctaaaa gcatcgctgt
    21841 agatacgatt atgcacttta ttcgtggtcg agttaatgcc cagtattcag accttcaagc
    21901 catgcaccat ctagccaatg gccaaatcga aaccctgcaa ttccatatca aggaagccaa
    21961 taaaatgact gccaaacctc tttctcaact gaaattgaaa aaagaggttc ttattgcagc
    22021 cattattcga aagggcaaga ctattttccc aactggggag gatatgttgg aagttggaga
    22081 caagctccta gtaacaacct tgttgccaaa catcaccaag atttatgact tgattgcgag
    22141 gtaagaaatg aataaaagta tgattcgtta cctcctttca aagttacttt tgattgaagc
    22201 tgttctcctc ttggttcctg tggctatcgc tgtctattac cgtgaatcga gccaagtctt
    22261 tacagccctc ttttcaacca tagggattct cgtattgtta ggcggttcag ggagtttaca
    22321 gaagccaaaa aatcaacgga tttatgccaa ggagggagtc ttgatcgttg ccctctgttg
    22381 gatcctttgg tctttctttg gtggtctccc ctttgtcttt tctgggcaaa tccccagcct
    22441 tattgatgcc ttttttgaaa ttagttctgg gtttacaact actggagcaa gtattttgaa
    22501 cgacgtttcg gttctcagcc gttccctcct cttctggcga agttttaccc acttgattgg
    22561 agggatggga gtgcttgttt ttgcacttgc tattatggac aatgccaaaa atagccacct
    22621 agaggtgatg aaggctgagg ttccaggtcc tgtttttggc aaggttgtat ccaaactaaa
    22681 aaacactgcc cagattctct atctccttta tctagctctc ttctccctct ttgtcatcat
    22741 ctattatcta gctggtatgc ctctctacga tagttttgtc attgctatgg ggacagcggg
    22801 aactggagga tttaccgtct ataacgatgg aattgcccac tatggtagct cactgattac
    22861 ctatctggtt agtataggag ttttggtttt tggggtaaat ttcaatctct actactacct
    22921 tatgctccgt cgggttaagg ccttctttgg agatgaagag cttcgggctt acttggtcat
    22981 cgtgctggtt tctacaggct tgattaccct caatactctc tacctctacc caggattttc
    23041 caaaagcttt gaaatggcct tcttccaggt ttccaacatc attacaacaa ctggttttgg
    23101 atatggagat attaccaact ggcccctctt ctcccagttt atcctcctct tcctcatgac
    23161 aatcggtggt tctgctggat caactgcagg tggactcaag attattcgag gcctcatcct
    23221 ttcaaaaatt gccaaaaatc aaattttgtc cattctatct ccccaccgtg ttttgactct
    23281 ccatgtgaat aaaacggtga ttgataagga tacccagcat aaaattctca agtactttgt
    23341 catctatgct atgattttgc tatcccttat ctttattgtc agcctagata gcaatgattt
    23401 tctgatcgtg accagcgctg tctttagctg tttcaataat atcgggccta ttctaggaac
    23461 cacttctagt ttctcaatct ttagtcctat ctcaaaaatt ctcctctcct ttgcaatgat
    23521 tgcaggccgc ttggagattt acccaatcct acttctcttt atgaagagaa cttggtctaa
    23581 gagataaaat acaaaatccc tctttttaca attgtgaaag agggattttt atattaaaaa
    23641 gggggaacgt ttttaaatcc aagcctgtct gtaagcaaag ttcttactca aataaaagat
    23701 ggaaaaactt actacacagc ttggtaatgc tccaatacaa attgtaaggc tttacttgga
    23761 ttctttgtta aatgaatata ttccattcct ctggtagcaa ctatctgaat acctaatctt
    23821 tctgcatcca ccttcatctc tctataataa ctccgaactt gtggagccag aataattaaa
    23881 tcataaacac ccataatatc ataatgagct ccgtacgctc ctgaattcgc aatcactcta
    23941 acttctgcta attgagtgcc ctcgttaatt gcattggcta attgcgcact tgttccagac
    24001 cctgcacaaa gaaccagtac tttcaactcc ttacttttta ttacatctat ctcaccaggc
    24061 attatttcac ttgtatcctc ctctaaaata atatcatttg agcttgcaat atcttctttc
    24121 accagtaact gtctatcata cgctctacag aatggcaaat aaatcaatat gtcgacaact
    24181 aaaatcaaag ataaaaatac aaaggagata agttgaaaat tcgttccaat taacaatccc
    24241 aagggaccag gaaaggtcca aggtaactgg atataaaatc cattcattcc aaagaaatca
    24301 ataaagacct ttcctagaaa tacattcact ggtggagtca tcaaaaaagg gacaaaaaga
    24361 tagggattca aaataacagg cataccaaat agaagaggtt catttaccgc aaataaaaca
    24421 ggagtaattg tagctttacc taccgatttt aattgtttag accgcataaa gaaaatcaaa
    24481 ataaatggta caacaaaggt agcccccgtt cctccaatag cagcgatata attcccgaaa
    24541 ttaggtgtta aagaatgata agggaactgc ccatttgcaa gaagttgagc attctcttcc
    24601 atattgctca gttgcaaagc tgtaacagca ggtaagacaa tagatggtcc atgaattcca
    24661 acaaaccaaa gcaaagcaca cataaaccaa atcaacatca tagcaggata tgattctgcc
    24721 cccttaaaaa taggagtcaa tagttgttga aatacttggg caaaaggaac atctaaacta
    24781 aaccgagata caatatctaa caaaccacta ataagtaaaa caaaagaaaa agggaaaata
    24841 tctctaaaag cttgtgatat agccccagga acttccttag gtaaatgaat agtaatgtct
    24901 cgcttaatac agaatcggta aacatttaca gtaataaagg cactgacaaa cgaagttatc
    24961 aatccttgag atcctaaata gtttgtcgac aaacttgtag atcccgtctt ctcatcaact
    25021 acaagcgtta cagttaatac cagataacta catatggctg ccaacattgc agaaatatca
    25081 tttattacct ttccgtgagg catttttctg ttaacatttc caactaatga ctttccaaca
    25141 gtccctgaaa caataatacc caaaactccc atggttaaca tatacacttt tctcatccag
    25201 acaatagctg gactcggtaa ctctactccg aaatttttag gaatcataat aataatcatc
    25261 aaaaagcttg aaaacataat taaaggcata gtagcaatga atccatcttt aatagccatc
    25321 atatagttat tagtagaaat tttttcaaat ttcccttgtt gcttttcaat ggcagcgact
    25381 agcttatcca taaaactcct cctataaaaa attcaacctc atatttaaaa catattaaac
    25441 atcagtcaaa tcgctaacct taattccgtt ttagcccttt tacccaaaga gcacttttct
    25501 taatatatct cttctgtgtt tcataatcaa caaagaaaag accatatcgc ttattgtagc
    25561 cattcgccca agaaaattga tcttgcaaag accatataaa atagccttga atattgactc
    25621 ccctatctcg agcctctaaa actttgtgta aatgttgctc aatataacgg attcttttac
    25681 tgtcatcaat aatatcattc tcgccctctg gcttaacctc tttaagggct gtaccatttt
    25741 cagttaaata aatgaccgga tgttgaggat attcttcttt gatacgaagc aacatatcaa
    25801 ataacccttg aggataaata ttccaatccc aatctgttgt cggaatacca ggctttttta
    25861 caaattcacc tagagcattt aatttaaaag aagactgtcc ttttattcct gttgaattaa
    25921 attcttgtct attttcacct ttgtattcac gaataaattc tgaacgataa taattcatcc
    25981 caaacatcgt attaagaggt gcagctcttt tcataatttc taaatcacca tcttcaataa
    26041 taaagctaga attattagct tccaatattt gattcaagtg aaaaagcgtg tcatcactgt
    26101 agtagcccaa aaaagttcca tctaatagaa atttattatt ataaacatca taccgtttag
    26161 ctgctaaaat attttctttt tgcccatcaa taggatagcc tggctttaaa gcatgaatac
    26221 aacctatctt tccctcaatc cctaattgat gaaattcgag gactgcaaga gcatgcgcca
    26281 acaacatatt atgattcgct tgaattgctt cagataattg aaaatgatga tttggaggaa
    26341 actgacctcc tatatattga cctgcagcaa gagacatcag ttcattgatt gtaaaccaat
    26401 gcttgacttc tgtaaattct tggaaacaaa agcgagcata tcgtatgaaa cgatcaatat
    26461 tctctctatt caaccaatcc cctgtttcta acattttctg aggcgaatca aaatgatgta
    26521 aagaaacaaa cggaatcaca ttatgtttta agcaagactg aaagactcta tggtaataac
    26581 gaacagctaa tatattaggc tccccatcta tatcaggaaa tatacgaacc caagaaatag
    26641 ataaacgcaa agcctgcaaa ccatgttctg ccgccaaagc tatatcctct tcgtaacgat
    26701 aataaaaatc actagctgga tctggtaaga acggactgtt ttcttgcaaa taaacatccc
    26761 acatatttgt tcctttgcca tctaccctag ttgcaccctc tacttgataa gcagcggtag
    26821 cagctcctaa taaaaactcc ttcggtaagg ctttaacctg taaattttcc atgactaatc
    26881 ctcattgcaa accaatatgt tcttcaatct ttcgaattcg ttcatattca tcaataaaaa
    26941 acttgacctg atcatacaat agcatcgttg tcatcaaagt atcttgacca tgaatcatga
    27001 taaaactcac ttcaaaatta tctccagatg cctcctccgc taataaatta gtctgttctc
    27061 gatgggcaga cactattgag tcgtttgcag actcaaccaa ttctcttgcc tgttcaaaat
    27121 atccatctct cgcaaacgcc aaagcatcca tcaaatctga ccttgcatct cctgcgtaag
    27181 cgacaattgt aaaaccaagc atatttattt cttcttttga tttcatcttt cttcctcctc
    27241 aatcttgatc catcttttac acatcattat taaaatgact tcgctacgat ataaatagaa
    27301 agtcgaccct aaatatctta aaaatcctta aatttcataa tatttaggat caatcttctc
    27361 tgaatacctt ggttcatttt ctatacttat gatttataag tggaaaccag cgtaattttt
    27421 tgctacttca attacacgat aaacatccaa attagattgg aatagcagtt cgtgcccacg
    27481 gatataattc aacacatttc tccattcatc ttgagcttgc cttgtttttc cggttgcttg
    27541 aagatataaa gccttcgcca tcttaacaac atattcacga tgataactga gctgtttcca
    27601 ttcatccttt tgactattta ataacttaga aatattttcc tcaataattg gcaaaaaatt
    27661 atcagctaga ttgtaagcta tataataatg attcgctaaa acatcatttt gacgactgcc
    27721 aattgcatta aaataatcac atgaggaata actggataat ttttctaaat attcaacaac
    27781 agactgccaa tttgacccat acaaagcaga aaagtattct tcaatcaatt cttcataact
    27841 tcttgtcttc ttccagagca tttcccccat aacataatta ggaaaattat gagggaatcc
    27901 ggcacgtaat tcttgacacg aaatgtaacc gttcaaatgt aggttagaaa gataagatac
    27961 atctctgtaa atggtttgac taattttcat atagcctaaa tcgccataat gagcacgccc
    28021 taaaggatag tcatatacga aactatctcc tttaaatgtt ttttgccact caaaaagata
    28081 agataaattt tcctcaagag aattcggaag tataatttta ttacgcagat aaggtttagg
    28141 cgtaggtatg gaattgtcaa aatctacatc tgcataactc atttcaaatg ttcttgtaat
    28201 cggtgcaaac atcatggtaa agcgttcagg attatctaat ttttctttct gaggcgccca
    28261 tagcaactca tggtaaagca gaaaacaaat ctttgtatct aatccctcac tcgttaaagc
    28321 cctatccaat tgattgagaa tacgaatata ctgatccgaa accaattctt gtctacagtt
    28381 ttcgcattca caaatattat tacgagcatc cgacaaccat acatgtaagt agttaacatc
    28441 aggtcttttc ttggcataat ccttgataat ttctaccatc ttatccgcca catctggatt
    28501 tgaaaaatcc agactggtta aaatcggagc cgtattaaat aattctcgtt tcccgtttat
    28561 ttcagcgaca tacggtttct tctcctctga aatactaaga cctgattccc agccaaattt
    28621 tgaagagtaa cctaaaacct cacctgtcca tccatgacca acacgatgat gaataagacc
    28681 tcttttttgc aattctttat ccaacctatc actcaattct tgtactaatt catttgagaa
    28741 tttttcttta tttaggtatg gattaaactc atgttcatac caacgtttca aaaaagagta
    28801 aggattttca aactggatga aaaaactgtt catcccaatc ttaggtagcc aatcaatgaa
    28861 atctagtata ttttcaaatg aatccgctcc ctctatacat actcccctat gatagtaact
    28921 ggctgtttca tctatagata gctgtttatc taaaaaatct tcaaatcgta actctggaac
    28981 aaagtcatgt ctgcgccctg gtctagtata cacaacccca aattcatgaa acattcggta
    29041 aattccaata agtaaaccta caattgtatt agactcaatt ctccccttac ccttgtctaa
    29101 tgagataaga acatggtctt ttctgtcctc tttattgact aatcctacaa aaatatccgc
    29161 ttccttctcc tcgacaagct ctatgttagt cttaaagacc cgattcatat agtaacttaa
    29221 ttcctctaag gcaaagctag aataagtatt tttctgttga tcaaatactc tgataaccat
    29281 cttatttccc tccaacagta gctttttctt tttcaagatt gcgtttatct gcaattttga
    29341 aaaatggata ataaattgct acagaaacca aaatcaaaac aacttgtaat agagctcctc
    29401 gccaactagc tcctgtcgca aggaagcctc ctatgatcgg tggcattgtc cacggaagga
    29461 ttacacctgt tgtatagggt actaatccta cagccattga tacataggta atcaaggcat
    29521 tgattgtagg agtagcaata aacggaatca gcataatcgg atttaaaact gttggaaacg
    29581 taaatagaat agctgtattg atattaaaaa tagacggtat aatagctagc ttacctaatg
    29641 ttttattcgc acgactctta ctaaatagga agagacaaat cgcaagacca atagtcgctc
    29701 caccgccacc aataaataca aataaatctt taaacggtaa tgtaataatg tgttggagtg
    29761 tttgtcctgc agccacagct tcttggtttt ctgtagtaaa ttgtaaccaa actgggtcta
    29821 caaaagcatt taaaacttgt cccccattaa ctccacagaa ccaaaagaat gagtttacaa
    29881 taacacatag aatcatacct ggaagcgttc ctgcaattaa cttaagcggt gttccaacaa
    29941 ttgcacctag gagtccgttg agacctcctg caactcctgc cgcttcaaga ccttttaaga
    30001 ccagagccca caaaacaaaa gtagtaaagc caggtaaaag agctgaaaat gatttactta
    30061 ccacatctgg gacaccactt ggcattttta tcgtaattcc gcgctggata aacatacgat
    30121 aaatctctgc tgtaaccaat ccaatagtaa tcgccataaa caaagaagat gcattcaggc
    30181 tagaaaatgg tattgcgccg ccaaataact gcttgacctg ctccccattt ttatcataaa
    30241 ccatactcga aaaacgaggt gccatcaata caaaactgga taaggctatg atccctgccg
    30301 acggaccatc tgtaccatat ccttccgaca acctgtaggc aataccgaaa caagcgacca
    30361 aggagataat cgctactgtt gactgattca tagttgtcaa gatacttagc aatccaacac
    30421 tattcagcca atttgtaaaa gcctcttgag gccaactgat tagaataaga aataaagagc
    30481 cgactaaaat caaaggcatt gccatcataa atccttcacg aatagctttc aaatgccgtt
    30541 ggttgccaac tttttcacca aacggagcga cttttgtttc taaaaacgct aaaatattgt
    30601 tcatcaccgg aactcctttt tttatttttt ataaattaaa tataccacta acagaaagcg
    30661 ttgtcaatat attttttgtt gtttttacaa tattttttct ttgtatagaa taataatttt
    30721 aattgatttt ttcttatgtt taatataaaa taaaccaaag gaggaaacaa atgattacaa
    30781 aacaatcagc ctttttacaa aatagagcca ctatactgga gtttctatat cgaaatccag
    30841 caacatcccg tacagatatt gttaatgaaa caggacttac tccagcaaca acgactaaca
    30901 tcataaaaga gctaagcgaa cagtccctca tatacgaaac tggtgatgaa tttagcgagt
    30961 tttccggatc tggaagacgt agaaaaacta tttctatcac agataatatt ccgtatgttg
    31021 ttggaggtat tgaaataaac gtcctaggta tctttctcag tctatgtgac ttacaaggga
    31081 aaactctttt cgagacagaa attttgaatg aagattatcc tatttcagaa atcaattcca
    31141 ccattaccaa tatgataaaa acagctatag agtacgtccc tttggaaaca aaattacttg
    31201 gatttggctt atcaatacct ggacattata acaaagactc cggaagtatc attacaaaca
    31261 accccatatg ggaatctttt aatttattaa atgtaattaa aagattcaat tttcctttta
    31321 ttgtaaaaaa taatatcgat tgtatggcta taggacaata cctttttaat ccacacaata
    31381 cccccgataa ctttattttc ctacacgctg gattaggtat ttacacttcc tttttcacaa
    31441 aagaaaaaat aggagcctct aaaaatcctt atatcggaga aattggacac accattgtcg
    31501 aattgaatgg gcaatattgt gaatgcggaa aaaaaggttg tttacaaaca tatatttcgg
    31561 atgcttggtt aatcaaacac gcccaattat tatttaaaaa ttcccaacta actgtactaa
    31621 aaagccttgt aaagactgaa aaagacattc atttagacac ccttttaacg gcttataatt
    31681 taggcgactc cgctttacgt caacaaattg ataaaggagt caatttatta gccacttcta
    31741 ttgcaaatct cctcctcatc aatcctgctg ataaaatcta tatcaacagt caattgctta
    31801 attatcaacc tttcactcat gaagtcaggg ataaaatcca agaccagctc cacttcgttc
    31861 cctttactcg taatatagaa attgaaattt taccttacaa caaacatcgt ggaagtatag
    31921 gagcttgtgc attagctatc gtcgcttttt tcatagaaca tagcaatgta ttacaagata
    31981 ttatttcacc ttaatatatt agaaatctat agacctgttt aaatcaacta taacctgtag
    32041 tagatatctc gtatttagac aatatgaaaa caagacgact tccatatagg aaaccgcctt
    32101 ctcgctatgt tgagtgattt atattaaaat aacttttctt ctagctgcat tttattatta
    32161 taaaaacatt catcataacc cccagaactt aaataacaat ttttattcaa gatacatact
    32221 cctagaataa actttatatg aaattctcat ttttgttttt acaattctcc ttagttaaat
    32281 cttgtttaat atatgtttta catatagtat ttagcgccac atagtactga actctctcca
    32341 aaaacggtta ttcctctttg aatagggcgt tatcacaaga aaagcatctc cacgtttcaa
    32401 cttcatatgg ctcaaaaaca atcaattgat gctaaaacct gtacctagat gtttcggttc
    32461 ataaaaccat gaaactgtaa aagtggatga aattgatagc gatagtcaaa tcaagaggca
    32521 tcataactct aaaaagtcac aatatataag ttcatcctcg gaaaaatatc attctaattg
    32581 ttgaaatgcc tacatgaaaa gaaacgtcaa atgctcatga aacaacgaat acaggtatca
    32641 aaactatgac aaaacaagtc cctaaattta ctaaagacac tgctcaactt tacacctgta
    32701 aatggttgtt gtataataaa gttacaaaga tgtacgacca cactgttgta aatcatagtg
    32761 ttcgcgaata tattactgat agcatttcta caaatacaat tgaagagact ggatagactt
    32821 taaacgaaat atgtcagtgt tttggcattc ctagccttca tatcatttaa agaattctat
    32881 agacaaaatt tttcccaata cagacactcc taacaactgc ttcatttttc taccaacata
    32941 tttaggaaca ggataagata caagaggatt aatccataga tcagttctat accaatctaa
    33001 gacaaataag ctaaaaaaac gattgataat aagcaaatag attccaaatt ttctctatct
    33061 gctcatttta ataaacaata ctagtgtaac tatccttcca gtcagaagct tgtcaaatca
    33121 caccgaaaat tcttctaaaa tttatctcgt taggcaatca agcaaaaact cgacgatagt
    33181 acaaacatta tcatacagaa ttgacttcct aaattatata ctttagtaag gttttcgtat
    33241 aagaaaaaag attcatttta catttctaaa cattcttttc taagatgaaa aacagaattt
    33301 ttcgattgtg atttaaagca acaagaagat tttcagtatc atcctataga tacgagctaa
    33361 ttaagaaaaa ctacattttc gaatataaac tacaataata taaactaaat tttataggag
    33421 gaagacaatg gattggtacg attatatgat acaggcatcc aaacaatcac aattcaacgc
    33481 aagccattgg tttcgctatt tgcgaaaagt tatttttgaa gactattctt atttaacaaa
    33541 ccaagatgta gaaaagttgc tagactccaa agaactaacc cgttttcaaa aaattagctt
    33601 gaagtatgcc tttcaagagc atactccaac tcataaatat gtgatttcat taaataaacc
    33661 tgctaagtta accaatgttc aaaaattgat ggagaaatac aaacatggat aaaatgaaac
    33721 cggtcttcca agccctaaat aaggaattaa ttcaggaaaa tctgacttta acaattatct
    33781 gtgtcgatgg ttatgtctta gaatatcatg gtttacgtgc cacacaagat gttgatgctt
    33841 tttatgacca aaatcagaaa atcaatgaaa ttattgctcg tgtaggaaaa cagtttaatc
    33901 ttaacatcca cgaagagtta tggctcaaca atcatgttgc aaagcaaata tgaacaaaca
    33961 acctccctta agtttatgcg aatccttgta ctcatttgag aatctgaccg ttttagtagt
    34021 ccctattgag tatgtgttag gaatgaagat gatgagtatc agagagcagg atttgcaaga
    34081 tattggtgca attattaaat acaaaaactt tcattcacca ttcgatacct ttaaatattt
    34141 aaaagacatg ggatttgata ctattgacct ctctgttcta ttagaaggtt ttagttatgc
    34201 ttatggtatg gattggttag aaaaattttt taaagaaaat caagataaac ttcgcgaatt
    34261 ttattaacag tatcaaacaa gatgattgtc aattagccag tcgtcttgtt ttttatgatg
    34321 aaatgaaata aaatctgaac aaatcgctta gagaattcca gtcaatttct agcgctgttt
    34381 gagacgtttc agtggactat agtaaaatga aataagaata ggacaaatcg atcaggacag
    34441 tcaaatcgat ttctaagaat gttttagaaa taaaggtgta ctattctagt ttcaatctat
    34501 tatatttcag attcggtcca ctattccttc ccaaaaacat tgcatattgc gtcaaaggaa
    34561 ttgctcacac tatcccaagc acaaaaccct cagtcgattg accgagggtt cctttttatt
    34621 attcaagaac ttgattagct caatgcatcc aaggcgtcat ccattgaaag aacttcgtgg
    34681 aagacacgtt gtgtcaattc agttttttgt tctggagtga ggtatttagt gtttacacag
    34741 tatccagaga tacgtacgat aacgtcttcg cctgacatga tcttttcgta aacatcgttc
    34801 aagtccataa cgttcaagtt aacgtgttgt ccaccgtttt cgaagtaacc atcaaggatt
    34861 gttaccaagt tatcaacttg ttcatcacga gtcttaccaa gagcgcgagg tgatacttgt
    34921 gtagtcaatg agataccgtc agctgcataa ctaaagtcaa ggctagaaag tgagttcaag
    34981 ttttgcaacc aaccaccttt agctttgtta gatgggttag cacctggtga gaagaattca
    35041 agtttagaca agttcacaga accatcttcg ttgaggtata cacctttgtg aactggtgag
    35101 ttaccagttt gtttagagta agcaacgtta gatgtgattg tcaaaagtga tactgtagct
    35161 tctgcgtctt tgtatagttt gtggctacgt agacgagttg tgtaagcttc gatcaaccat
    35221 tctgccaatt cgtttgaacg tgggtcatct tcaccccagc gtgggtagtc accgattgtt
    35281 tcgtaatcgt agatgtagcc atcttcgtca cggattggtt taactgtagc gtatttgata
    35341 gctgacaatg tatcaacagt gttagcaaat ccacagatac cgaatcccat gttggcacgt
    35401 tgtttagttg gcaagaaggc catttgaaca gcttcgtagt tgtacctatc agtcatgtag
    35461 tggatgatgt tcaaggcatc tacgtaagtg tcagtcaacc agtcaagaga tttttcaaag
    35521 ttcgctttaa ctgattcgaa ttcaagaact tcgtcacgga ttggttcgat atcaaatact
    35581 ttgtagtctt tgtgaacatc gtcgtaacca ccattcaaac cagtaagaag ggctttaaga
    35641 acgtttacac gagcaccgaa gtactggatg ttgtggcgtt gttcttcatt ttctggatca
    35701 agtggagaca cacagcatga gatacagctc atttcaccat atccgtcttt agccattgtt
    35761 gttacacctt cgtattggat agaagagtgt ttgtggctca tgtgcataca gtagcgacgg
    35821 aagttgtatg gcaatttgtc agtccaaaga actgtcaagt ttggttctgg tgagttaccg
    35881 atgttgtcaa gagtgttcaa gaaacggtag tccatcttag taacacggtg acgaccgtcg
    35941 ttacccatac cagccataga agttgtgata aaggttgggt cacctgagta caattggtca
    36001 taagcttttg tacgagcaaa tttaactgta cgaagtttca taacgaaatc atcaacgaat
    36061 tcttggattt ctgattcagt aaatgtacca cgagcaaggt cacgttctgc aaagatgtcc
    36121 aatacgattg gtacacgacc tagagatgta gcagcaccgt taatcacacg gcagacagcc
    36181 atgaaagcaa tgttaaccca ttggattgct tctttcacgt tcatcgctgg tttgcgaaca
    36241 tcaaccccgt aaaggtcacc caggcgaaca acttgttgca atgcttggta ttgaaggttt
    36301 acttcttcac gaagacggat tgtttcttca tcgatttctt tgattgcatt ccagtcgttt
    36361 actttttctt gcatcaagta gtctgcaccg taaagagcaa gacgtgcgta aacaccgatg
    36421 atacgtccgc gtgagtatgc atctggaaga ccagttacag tgtgtgcatg acgagcgcga
    36481 cgaatatttg aagtgtaggc acggaaaata ccgtcgttaa ctgttgttac atatttagtg
    36541 aagatttcgt gaacagctgg gtctggttcg tatccatttt cttttaaagt agtttcagcc
    36601 atacggatac caccttttgg catgaagttc aatttgaaga gttcatcatt ttggatacca
    36661 aagataactt cattttcttt gtcgataaat ccagcaggga tatcagcgat agatgttgga
    36721 cgagtgtcca ttgggaaacg agtttcttcg tagtgtgctt tagtttcttc tacaattttc
    36781 ttgatgtgaa gtgaacgctc tgttggtcct gcaaggaagc tttcgtctcc atcataaggt
    36841 gtgtagttag cttgtacaaa gcgtgataca cttgcttttt ctttccaatc tacgcctttg
    36901 aagccttccc aagctttgtc aaaaatatct tgtgcttcaa caactgtctt aacaaccata
    36961 ttaatatcct cttttttcta gtaacagtca tctgttacat tcataagaca agtataccat
    37021 aaagtaaccg atttcaacaa gtgcaaaatc cctattttta cactttcttt tctaaaacag
    37081 tctatatttt atttcaaact gtattatatt tttgaaaaaa ataaagtcct tttttctttt
    37141 tttcagaaaa aagggtataa taaaagaaaa taagcagtaa cactcaatgg aaatcgaaaa
    37201 gcaaactagg aagctagccg cagattgctc aaaacactgt tttgaggttg cagatagagc
    37261 tgacgtggtt tgaagagatt tttgaaaagt ataaaaaggt gctaggcatg ttgatttttc
    37321 ctttgttaaa tgatttgtca agaaaaatca tccatattga catggatgcc ttttttgctg
    37381 cagtggaaat cagggataat cctaaactca gaggaaaacc tgtcattatt ggaagcaacc
    37441 ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag ttatgaggca agagcttttg
    37501 gtgtccattc tgccatgagt tccaaggaag cttatgaacg ttgtccccag gctgtcttta
    37561 tctcagggaa ttatgagaaa tacaagtctg tgggactcca gattcgagct atttttaagc
    37621 gctatacaga tttgattgaa cccatgagta ttgacgaagc ctatttggat gtgacagaaa
    37681 ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct cattcaaaaa gatatctggc
    37741 aagaactcca tctaactgct tctgccggta tttcctataa caagttctta gctaaaatgg
    37801 cgagtgatta tcaaaaacct catggtttga cagtgattct acctgaacag gctgaggatt
    37861 ttctcaaaca aatggatatt tccaaatttc atggagtagg aaaaaagaca gtagaacgtc
    37921 ttcatcaaat gggcgttttt actggtgctg atttacttga agttcctgag gtgaccctaa
    37981 tagaccgttt tggtagacta ggctatgatc tgtatcgaaa ggctcgtggc attcacaact
    38041 ctccagtcaa atccaatcgc atccgtaaat caatcggcaa ggagaaaacc tacgggaaga
    38101 ttctccgtgc tgaggaagat atcaaaaaag agctgactct tctatcagaa aaagtcgctc
    38161 tcaatctaca tcaacaagaa aaagctggaa aaattgtcat tttgaaaatc cgctacgagg
    38221 acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa aacacaagat gctagtcaga
    38281 taagccaaat agccctgcaa ctctatgaag aattaagtga gaaagaaaga ggtgtccgcc
    38341 tattggggat taccatgact ggattttaaa gctcaatgaa aatcaaagag caaactagga
    38401 ggctagccgc aggctgctca aaacactgtt ttgaggttgc agataaagct gacgcggttt
    38461 gaagagattt tctaagagta taaaaccttg aagagttgcc ccttcaaggt ttttcttata
    38521 caaataaacg gacaaaactg taaagtagca aaacactacc aagcacgata cggtatttac
    38581 caaaaagggt gaagtcgtgt tttttcacat agctggtcaa gaagcgaata gccaccatgc
    38641 tgaccgcaaa agctactccc atcgcgacca agagcaaaaa caattgccca aagctcaaga
    38701 gttctccggc tttcacaaat ttgaaaatct ttaaggcact agctccaaac ataacgggaa
    38761 tcccaagata gaaggtaaat tctgtcacaa ctgaacgact ggttccattt aacaaaccac
    38821 cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag agcaagaact tggaagagtc
    38881 cgatatagaa agcggtcgta taaggaagct tgtccaactc tgttacactt ggctcgatag
    38941 cacgcgcttt attgcgcttt tccaaataga tgaaggcaac cccgtagata atcaacatga
    39001 gagcaactga aaccatgtta tggaagtggg tatcaaacca atcatcaaat ttaaagacac
    39061 caagtaaagg caaagtggca atcaagacct tcaaccatag tctccaagtc ttacgaactt
    39121 cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt aaaataaatc accataactg
    39181 ctaaaatagc accaagctga atcacgacat taaacatgga cataaaggct tcattttgat
    39241 tttggtattg gataaactcc tctgctaaaa tcaagtgacc tgtactggaa atcggcaacc
    39301 attccgtaat tccttcaaca atcccgaaga agatagattt taaaatttca ataagataca
    39361 tatatttctc cttatattat atttaacgca gttagctact gccaaagccc aagtggtata
    39421 cttggaataa gccactgtgg attagttcat ttcctccaat cgcttgacga tttccgaaag
    39481 ggtctaacca cagctttttg tttcaattgg taatgagttt gataacgcat agacgtttta
    39541 tctcgtctaa ggtaacaagg caaaaagttc gtggataacc aagtagactt gaaatactat
    39601 atctggaggt actcccatgc tttatgtggg cattgatgtc gctaaaaata aacacgatgt
    39661 tacagccttg aatgttcgag gaaaactgtt cttaaaccac tcactttttc aaataataaa
    39721 gctggttttg aacttttaga tctgtctctt cgacagctca accaagacta tctcatcgct
    39781 cttgaagata ccggacatta tgcctttaat ctactgaact tcctgcatga acaaggatat
    39841 aaagtttaca cctacaatcc tttgctcatc aagaaatttg ccaaatcatt attacttcgc
    39901 aagactaaaa cggataagaa agacgctcat ggcatcgctc ttaaacttct ttctgacccc
    39961 aatcgtgaac aatttcaaca cgataatcgg caagtagaac taaaaatact ggctagacat
    40021 attcatcgtc tcaagaaaaa acagtctgat tggaaagtgc aatacactcg ttgtcttgat
    40081 atcatctttc ctgagttgga taaaatcgtt ggaaagcatt cagaatatac ctaccaactc
    40141 ttgacatgct accctaatcc tcagaaaagg cttgaggcag gatttgataa gctgatagaa
    40201 attaagcgat tgaccgcttc taaaattcag gatatcctct cagtcgcacc tcgttctatc
    40261 ggaacaacat ctcctgctcg tgaattcgaa atcatcgaaa acatcaaaca ttacaagagg
    40321 ctcattgaca aggcggaaaa atgtgtcaat gacttgatgg ctgagttcaa ctcggtcatc
    40381 acgacggtta ctgggattgg gaatcgttta ggggcggtca ttttagccga gattcaaaat
    40441 attcatgcct ttgataatcc tgctcaatta caagctttcg ctggactgga ttcttctatt
    40501 tatcagtcag gtcagattga tttagctgga agaatgatca aacggggttc ccctcatctg
    40561 cggtaggcac tcatacaagc tgccaaagca tgcgctcgct tttcacctgc ttttaagacc
    40621 tatcttaaga ctaagttaga ataaggaaaa cattacaatg tagccatcat ccaccttgca
    40681 aaaaaactta tccgaaccct gttttatatc ctaaaaaaga gctgccattt gacgaacaaa
    40741 aagtgatgta atttctgaaa tcaacacagg attacctttg aaaaaatgga ctttttcaag
    40801 ggctttttgc cgtgctctaa aatcatcgcc aaatcatcaa attgaaataa gaaatagttt
    40861 agataaaact attgactttt cttatagttt gtcttttttc tatcttccat tatatcatac
    40921 tttttcagtc tatggtagct ctctttaaaa ggcaccgata ctgccgccac ctccgcctcc
    40981 agagaagcca ccaccagaac ttccacttcc agaagataca gagtaggtgc ttgctgtatt
    41041 tgcgacacta gcataatggc tcatttgtgc tgttgaatga taaaacatac tgtgccagcc
    41101 ataagctaca tagaaattga tatctggatt ttccacttga atctgatgaa ccttcatcaa
    41161 atgactaacc ttgtccgcat agccaaataa ggtcgcatag accaagaggc gattccagac
    41221 cacaatactt tccagttcag cctgatccaa tcgtgcaatc tcacgcaaca tattttcaaa
    41281 actggtccag agatagtaga cctcagctcc cgcttcattt agaacaccat cacgattatc
    41341 tagttgaagc ttccaataat agaaaacaga caaaactaac cctagaaaac caagtattgg
    41401 caaggggagg taaagatagc catgaacgtc taaactgtac aagaacaaac caaatccgat
    41461 aaataggggc aagatagtca agacacccat acccacttgc aaagcctttt ccaaaccagt
    41521 taaaggacga tagtaatctg ggagtcccca gaagacaact cgctttctca ctccttcttg
    41581 catctctttt aatactgctt cgaaagaaga tttgagctga attcctcttg cttgaatccg
    41641 tttttcatca gaaactttgg ctctacgata aagactatca gataccttgt aatccgcaaa
    41701 caaattggaa agagtttctt cttttttacc tgaaaaagct agatttaggc agtctttctc
    41761 aaagcttgac aaaccatctt cttttactag cctcaaacca actgcatctc cttctgaaat
    41821 gatagagaca ttcccacggt ctatcacatc tagcaaggta gcttgaataa gttgatcaaa
    41881 ggtgaatttt ccagctccct tgaccaaggg actcacttcc tccaaggagg tcgagtagac
    41941 tgcttctgat aaaaccatag gctctaattc cattggtggt tcatagagac gatgattttt
    42001 ggcatatttg actgaaggag tggtctttct tctataaata aaatagaagc agacactcaa
    42061 taacaaggag atagaaagga tcgaagggaa gatccaagta agtagttgtt tactttgctc
    42121 tttttcttta acaatcgaat cctctatctt attaaactct tctaaacgat tccctttcaa
    42181 gccctgatcc ctagcgctag caaaatcagt tcgcggccag taggcatgca attcaactcc
    42241 acgcttagcc ggaagattgt ctaaacgaat agtataatca aggttactct tttcaaccgt
    42301 tctctctcta aaaagtttcc ctgtatggaa aaagagtttc tcagccccct tgtctcccct
    42361 tacatgaaat tcaaactttt caatagactc tgaactatct gtcagaggtt gccaatttaa
    42421 ttcagcgata tcatcataaa ggaaaagtaa attttttaag ttccagacga ggtcaacttc
    42481 aactatgtcg ccctcctgac ctggattata gactctcaca gtataaccat ccgcttcttc
    42541 tgttacttcg ctagtcacat ctgctggttc tgcaccgttt ttcgcggcct gaatctttgg
    42601 atgagggtca atgtcaaacc cgctaggcat cttaccagca cgtccaagtc ccacgatttg
    42661 gcccttaaag tcctcctcaa actggtaaac tatcttctgt ctaaactctg ccgtattgtc
    42721 tgcatgaata tacaaatccc cttgataaga gtttatcttg aaatcaatgg caaaaacaga
    42781 gagtggaaga aggcaaaaca agcctaacac cagtaagaaa aaagtttttt tcatcaacta
    42841 agcccccttt ttatctttct tatcattata gcattttttc gtaagtaaag gcttacttat
    42901 gttgaaaaat tacgcatttt tcgataaaat aggagacagt tattttttaa tagatcagaa
    42961 taggagaaat catgagaaaa atatacttat ctattttcac aagtctcttg ctgatgctag
    43021 gacttgtcaa tgttgctcaa gccgatgaat atttacgcat cgggatggaa gcagcatatg
    43081 ctccctttaa ctggacccag gatgatgata gcaacggagc tgtcaaaatc gatgggacca
    43141 atcagtatgc caacggatac gatgttcaaa tcgccaagaa aatcgctaag gacttaggta
    43201 aagaaccttt ggttgttaaa accaagtggg aaggtctagt ccctgccctt acttctggta
    43261 agattgacat gattatcgca ggtatgagtc caactgcaga acgcaaacaa gaaattgcct
    43321 tttcgagcag ttactacact agcgaaccag ttttgcttgt caaaaaagat tctgcctacg
    43381 caagtgctaa atctttggat gactttaacg gtgcaaaaat cacttctcaa caaggggtct
    43441 acctctacga cttgattgca caaatcccag gtgctaaaaa agaaacagcc atgggagact
    43501 tcgctcaaat gcgccaagct cttgaggctg gtgtcattga tgcttatgtt tctgaacgtc
    43561 cagaagcact gactgctgaa gctgcgaact ctaagttcaa gatgattcaa gtagaacctg
    43621 gtttcaaaac tggggaagaa gatacagcta tcgctatcgg gcttcgtaaa aatgacaatc
    43681 gtattagcca aatcaatgcc agcattgaaa ccatttcaaa agatgaccaa gttgccttga
    43741 tggatcgtat gatcaaggaa caacctgccg aagctacaac aactgaagag actagcagta
    43801 gtttctttag ccaagtcgct aaaattcttt ctgaaaactg gcaacaactc ttgcgtggtg
    43861 ctggtatcac tcttttaatc tctatcgtcg gaaccatcat aggtctcatt attggacttg
    43921 ccattggtgt cttccgtact gctcctctct ctgaaaacaa agccatttat ggccttcaaa
    43981 aactagtcgg ctgggttctc aatgtctaca ttgaaatttt ccgtggtacg ccaatgattg
    44041 ttcaatcgat ggttatctac tatggaactg cccaagcttt cgggatcaac cttgaccgta
    44101 cactagctgc tatcttcatc gtttcaatca ataccggtgc ctacatgact gaaatcgtcc
    44161 gtggtggtat cctagcagtt gacaagggac aatttgaagc tgcgactgct cttggtatga
    44221 cccataacca gaccatgcgt aagattgtcc tacctcaggt agtccgtaac atcctacctg
    44281 caactggtaa tgaatttgtc atcaatatca aagatacatc tgtattgaac gttatctctg
    44341 ttgtcgaact ttatttctca ggaaataccg tggcaacaca aacctatcaa tacttccaga
    44401 catttacaat cattgccgtg atttactttg tcctcacctt caccgtaaca cgtatcctac
    44461 gctttatcga gcgcagaatg gacatggata cctacactac aggtgctaac caaatgcaaa
    44521 cggaggattt gaaataatga cacaagcaat ccttgaaatt aaacacctca aaaaatccta
    44581 tggacaaaac gaagtgctaa aagacatttc tctcactgtc cacaagggag aagttatttc
    44641 tatcatcgga agctctggaa gtgggaaatc aaccttccta cgctccatta acctacttga
    44701 aacgccaact gatggacaaa tcctttatca tggacaaaac gtcctcgaaa aaggctatga
    44761 cctcacgcaa taccgtgaaa agttagggat ggttttccaa tcctttaacc tctttgaaaa
    44821 tctcaacgtt cttgaaaaca caatcgtcgc tcagacaact gtccttaaac gcgaacgcac
    44881 agaagctgaa gaaattgcca aagaaaacct ggaaaaggtc ggcatgggag aacgctactg
    44941 gcaagccaaa cccaaacaac tctcaggtgg tcaaaaacaa cgtgtggcca ttgctcgtgc
    45001 cctttcaatg aatcctgacg ccattctctt tgatgaacca acatcagctc ttgatccaga
    45061 aatggttgga gaggtcctca aaatcatgca agatctggct caggaaggct tgaccatgat
    45121 tgtcgtaacc catgaaatgg aatttgcccg tgatgtctct caccgtgtta tctttatgga
    45181 taagggcgtg atcgctgaag aaggtaaacc agaagacctc ttcaccaatc ctaaagaaga
    45241 ccgaacaaaa gagttccttc aacgctatct caaataaaaa gaaaaggctg catcaaccgt
    45301 gcagtctttt tgctgtcctc aaaatgaaaa ggcagattct ctatctctac tacttgaagg
    45361 tcaagaatcc gctgttatcc aaagattaat cttcaaattt ttcataattt ttttcataga
    45421 aatcaattag gcctagggct gtttcaaatg aaatattttt tacttttgca cgaccctgcg
    45481 ccagagcaat gatagacatt tcacgcgcat tcgtttcttt agagatacgg tagcctgtga
    45541 ttttcttatc acgaacccag ccaacaactg attctacttt ttcaaagttt gacttagcca
    45601 tgtttttctc ctattttctt ctttacaata tttaattgta tacgttttta ctacttttgt
    45661 caataaaaaa aaacatatat tcaacgaaaa taattagttc agaattttct tacttccttt
    45721 ttaaatccta taatatatag gttttgctag cctctacacc ataaatattt gctaacaaaa
    45781 atactgtatt attaccctct taaggtgcga aattattcaa gttcttaaaa aatgcttctc
    45841 tatttccgta agatagctta tttcttcgat ttaagaactg aagatgatag ttctaacctt
    45901 tagaaatcca agccttcact agctcaaaaa ctcctatctt ttttcctcaa taaatcatct
    45961 gagagatagg tattccttat atccttcaaa ttcatcactc ctttggatat tgaggtgcta
    46021 gcctagaagc agacacccga ttatctaaac catccttaat agagatgaca agacagataa
    46081 gctcagttaa ttacttatat atctttttaa tatggtatat ttgtcaacaa aaagaaatca
    46141 aatcatacct tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaagttgc
    46201 tcaaaacact gttttgaggt tgcagataga gctaacgtgg tttgaagaga ttttcgaaga
    46261 gtattaaaga cagtgtgact atgcttgtca atagatagga aatcaaaatg aaggatggaa
    46321 atctgagcca aacatcataa gtgctataat gaacagaagt aagaattgca cgataagttt
    46381 cctaaaacca taggaatcgt cccctttctt catcttcatt atagcacata tacatcagtt
    46441 gtgcaaataa tatgatattt ttttattagt cctcagacaa gcatattata aagcgtttca
    46501 ttaccattta agttaatata agctggatca aaaccttcca ttctacggat caaacctgca
    46561 taatcatgct tatctgctaa agcgatccca attaatactg ggcctgttcc cttgctagct
    46621 cgtttgatat actcaaaacg tgtgatatca tcatttggcc ccaggatatc atttacaaac
    46681 tcacgcaaag ctcctggacg ttgtgggaaa ttgaccacaa aataatgttt gataccatca
    46741 taaatcaagg cacgctcttc catttctggc atacggttga tatcattatt tcctccagaa
    46801 atgatacaac aaatggtttt ccccttaata tattcagcta aaacctctaa agaggcgata
    46861 ctagccgctc cagcaggttc tgcgactatc ccttgcttag agtaaaggtc aatcaaggtt
    46921 tcagaaatca atccctcatc gacacctacc aaagtttgaa tatgttgacg agttgcttca
    46981 taggtcaact gacctacctt ttgcacagca atcccatcag caaatttatc aatttccttg
    47041 agttttactg gacctccagc ctcaaaggca gctttcatgg aacgcgctcc attcgcctct
    47101 actccgataa cctcaatctc tggacttgtt tccttgatat aggtagaaac cccggcaatg
    47161 agaccgccac caccaacagg aaccaagaca gcatcaaaat caatcgattc ttttcgagct
    47221 tcttctaaaa tctcataagc aactgttcct tgacctgctt gaacatgagc atcatcaaaa
    47281 ggatcaataa aggtacgatt ttcagagact gtaaattctt gagctgcttt ggctgaggca
    47341 tcaaaggtat ctccaactag tttaatagtt acaaaatccc caccaaaaaa gcgaacctga
    47401 ccaatctttt gttgtggcgt agtaataggc ataaagatag tagcaggaat tttcatttca
    47461 ttacaagtat aggctactcc ctgcgcatga tttcccgcag aagcgcaaac taccccacgt
    47521 tcacgttctt ccttgctgag ctgggaaatg gcataatagg caccacgaat tttaaaggag
    47581 cgaacacgct gggcattttc ttttttcaaa taaatcttag caccatactt ctccgataaa
    47641 taatgatcgt aatccagtgg agtattcaca accacaccgt tcaagacctt gtgagccttg
    47701 attatatctt ttgaacttaa catataaaac ctctttttct ataaaaaaca gtcactaatg
    47761 actgtttttt agttattcat ctccgaaaac ttcagtaaca ctttcatggt atttatgagc
    47821 catacgaatc gaaaactctt taggaagttc ataacgattt gtggaaatcc aatcatataa
    47881 ccattctacc aaactttctt cactatcatt acgatggaag ataaaatagt ttaaaatttc
    47941 tttatattct acatcattca aatccaacgt gtctacaaat tgactacgag gaacaaaatt
    48001 agaatctaat tttcttagtt gatctgtcaa ttctcccaat tgtaaatcca actgaaaaaa
    48061 tagtttttgc agttgcctat cagtttcatc acatcctgtc ttgatagaaa acaaattggt
    48121 aatattcata tgatttcaac ccctaaataa gtacatctaa tatcccacga atagctgaag
    48181 ctaaagtttt cgcagtccag tcatttaaac ccgattcttt caatccagat gcaataattt
    48241 gctctatttg atataaaccg ctatctatcg tctcatttat tctgcgaaga ggaccttcaa
    48301 tataggataa agcttctccg aatctaacag ctgatttagg tcctaatgat ttaccaacta
    48361 tatttgttaa tgttttttat ttctcaaaat ccatttcgct atataacgag cagatttagt
    48421 cgcaccagct ctctcaaacg gagaatgaat ttcaagacct tcttctctag ctatttgtgc
    48481 caatttgaag aattgttcaa aggtcatatg caacctacca tcttcaaaat tagcatcatc
    48541 ataaatgtta attacagcat tttcatcata cgaccaatct gctttatttt ggtctgctag
    48601 cactattacc gacggtgtaa ttacattata caactagaac caataataac gatgcaattt
    48661 ttctcataat ctttttcata aaatcatctc cagcgctata tatttctaat tagttataga
    48721 ttttgaatgc atcatcgtcg tttttaccaa cgaatggcat tgctttacgc aattctgcac
    48781 caactttttc aatttcaagg ttagctgctt gttcacggta agcagtcaat tttggacgtc
    48841 cagctttata gtcatttaca aagtcatttg caaatttacc attttggatg tctgccaaga
    48901 cagccttcat attttcttta acttgttcag tgattacacg tggacctgat acatagtcac
    48961 cgtattcagc agtgtttgaa atagattgac gcattttctt gaatccacct tcgtagatca
    49021 agtcaacgat caatttcatt tcgtgaagaa cttcaaagta agccaattct ggagcgtaac
    49081 ctgcttctgt caagacttcg aaacctgctt cgataagggc agtcaaacca ccacaaagta
    49141 cagcttgttc accaaacaaa tcttcttcag tttcttcttt gtaagttgtt tcaagaagac
    49201 ctacacgagc cgctccaaca cctttacacc agtccatagc aatgttttta gcatttcctg
    49261 ttgcatcttg gtatactgca taaagagctg gaacaccaaa tccttcttcg taagtacgac
    49321 gtaccaagtg tcctggtcct ttaggagcac acatgaagac atctacatcc gcaggaactt
    49381 tgataaattc aaagtggatg ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca
    49441 agtttggagc gatttctgct tcgtacaatt cttgttgaat ttcgtctggc gccaagatca
    49501 tgataacatc agccaactta gtagcttctg ctactgtgta agtatcaaat ccatcttctt
    49561 ttgctttatc aaaagattta cctggacgta cacctataat aacgtcacga cctgaatcac
    49621 gcaagttttg agcatgcgca tgcccttgtg aaccataacc gataacggcg atttttttac
    49681 cgtcaagtgc tgctacttta acatcttttt catattccat ttgaactgtc atagcttttc
    49741 tctcttttct attatttatt gccttttagg ctggtttaat aaatttaagt tggattttta
    49801 atcgcgggta aatccagttg cacccgttcg agcaatattg cgaataccgt atgggcgaat
    49861 gactctcaat agggcttcgc tcttttctgc atttcccgtc atctgaatgg taatcgagct
    49921 tggcgctacg tctaccactg ttgcacggaa aggttgaata atcgctaaaa tctcagctct
    49981 cttctcagct ggcgctgaca tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc
    50041 tgtaatatct cgaatgcgaa tcacatcaat ctgacgattg agctgtttga tgatttgctc
    50101 cacttcatca tgagaagcaa catcaataat aatagtgata cgcgatacat tcggatcttc
    50161 tgttgctcca acagagatgc tttcaatatt aacctgacga cgagatagga cacctgtaaa
    50221 gcgattgagg actcctgaac gattttgtag ttttgctgtt aacattctac gcatggaact
    50281 gcacccccaa catctcatga ttactcttac cagccggtac cattggtaac acctgttcct
    50341 tacgagaaat atctacctca attagcatag gaacatcctc agtgatgact tcaaggtctt
    50401 gagccaaggt ctcaggattg tcaaacttat agtttttaat accataagcc tgcgccatca
    50461 attggaaatc aggaaggata tcaaagaccg actctgatgt tctgccttca tagaaggatt
    50521 cctgccactg gcgaaccatt ccgagtgaat gattgttcag cataaccacc ttgattggca
    50581 ccttgtaaat attcaaaata gccaactcct ggttagtcat ttggaaacca ccatccccaa
    50641 caaacaagac tacttcctta tctgggttag caattttagc accgattgct gctggaattc
    50701 caaagcccat tgttcccaaa ccacctgaag tcactaactg acgttcattt tggtagggat
    50761 aatactgagc tgtccacatt tggtgttgac caacgtctgt taccacaatg gcatctccat
    50821 tcgtcaattc accaattcgt tcaataactg cttgcggttg aaccacacgc tctttcttgt
    50881 catacgaacg aacacgattc ttgtctttag tgactttctc aatccacttt tcagtattgt
    50941 tgtgaactgt tggttctgct agcaacattt gcaaggcctt cttagcatct ccaactacag
    51001 gaatgtctgc actgataatc ttgccaatct cagctgggtc aatatcaatg tgggcaacct
    51061 tagcattctt agcgaaagtc ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa
    51121 tactaatcat aaagtccgct tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc
    51181 ctcccattcc aagaaagagt gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg
    51241 ttaccactgg aatttgatag cgttctgcaa attcacttag ttccgtagca gcctcagcat
    51301 aactaattcc accaccagct aacaagactg gctttttagc cttggacaat tgcttcaaga
    51361 ttttcttgat ttgcatatca ttcggctcaa gagtcggctg ataacttggt aaattcactt
    51421 ctggtgaata aatgaagtct gtttctaaag cagatatgtc ttttggtagg tcaattacaa
    51481 ctggccctgg acggcctgta gttgcgatat ggacagcttc cgtaatgata cgcggaatat
    51541 cagctgtctc acgaacttgg taattgtact tagtgattgg catggtaatt cccacgatgt
    51601 ctgcctcctg aaaggcatcc ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca
    51661 agaggggaac gctatcgctc atggcatccg caatccctgt aatggcattt gttgctcctg
    51721 gtccactagt gacgacggca acacccaact ttccagttga tttggcataa ccttcagctt
    51781 catgcaaaca accttgctca tggcgcccta gaatgtggcg aatgccttta aaattatata
    51841 tcgcatcata aaaaggcaaa accgcaccac caggataacc aaagatggta tcaactccta
    51901 aatcacgaag tgtttccaaa actaggtccg accccgtctt aggagattct aaactgattt
    51961 tctccattgt tcccctttct ttcctct
//
LOCUS       DAVLHB010000010        48667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLHB010000010 DAVLHB010000000
VERSION     DAVLHB010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.010"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..197)
                     /locus_tag="VXE36_000660"
     CDS             complement(<1..197)
                     /locus_tag="VXE36_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779013.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASIL"
     gene            complement(528..824)
                     /locus_tag="VXE36_000661"
     CDS             complement(528..824)
                     /locus_tag="VXE36_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779014.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLTEYSKMK"
     gene            complement(808..2940)
                     /gene="pfbA"
                     /locus_tag="VXE36_000662"
     CDS             complement(808..2940)
                     /gene="pfbA"
                     /locus_tag="VXE36_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0779015.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPIEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEF
                     NSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSN
                     KIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4070..5296)
                     /locus_tag="VXE36_000663"
     CDS             complement(4070..5296)
                     /locus_tag="VXE36_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0779016.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFVGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5339..6031)
                     /locus_tag="VXE36_000664"
     CDS             complement(5339..6031)
                     /locus_tag="VXE36_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0779017.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(6204..7955)
                     /locus_tag="VXE36_000665"
     CDS             complement(6204..7955)
                     /locus_tag="VXE36_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779018.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEDLLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7945..9690)
                     /locus_tag="VXE36_000666"
     CDS             complement(7945..9690)
                     /locus_tag="VXE36_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779019.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRIGRKTHKAFGESQTAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9896..10192)
                     /locus_tag="VXE36_000667"
     CDS             complement(9896..10192)
                     /locus_tag="VXE36_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0779020.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10211..10348)
                     /locus_tag="VXE36_000668"
     CDS             complement(10211..10348)
                     /locus_tag="VXE36_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779021.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     P"
     gene            complement(10345..10801)
                     /locus_tag="VXE36_000669"
                     /pseudo
     CDS             complement(10345..10801)
                     /locus_tag="VXE36_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10935..11762
                     /gene="xth"
                     /locus_tag="VXE36_000670"
     CDS             10935..11762
                     /gene="xth"
                     /locus_tag="VXE36_000670"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0779022.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTITFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11774..11917
                     /locus_tag="VXE36_000671"
     CDS             11774..11917
                     /locus_tag="VXE36_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0779023.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11917..12156
                     /locus_tag="VXE36_000672"
     CDS             11917..12156
                     /locus_tag="VXE36_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0779024.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12539..12634
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13034..13615
                     /locus_tag="VXE36_000673"
     CDS             13034..13615
                     /locus_tag="VXE36_000673"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0779025.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13615..14877
                     /locus_tag="VXE36_000674"
     CDS             13615..14877
                     /locus_tag="VXE36_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0779026.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14964..15830)
                     /locus_tag="VXE36_000675"
     CDS             complement(14964..15830)
                     /locus_tag="VXE36_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEV0779027.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15817..16587)
                     /locus_tag="VXE36_000676"
     CDS             complement(15817..16587)
                     /locus_tag="VXE36_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0779028.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16613..17467)
                     /locus_tag="VXE36_000677"
     CDS             complement(16613..17467)
                     /locus_tag="VXE36_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV0779029.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17624..18028)
                     /locus_tag="VXE36_000678"
     CDS             complement(17624..18028)
                     /locus_tag="VXE36_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0779030.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VYITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(18098..19579)
                     /locus_tag="VXE36_000679"
     CDS             complement(18098..19579)
                     /locus_tag="VXE36_000679"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0779031.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            complement(19598..20776)
                     /locus_tag="VXE36_000680"
     CDS             complement(19598..20776)
                     /locus_tag="VXE36_000680"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0779032.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20940..21947
                     /gene="galR"
                     /locus_tag="VXE36_000681"
     CDS             20940..21947
                     /gene="galR"
                     /locus_tag="VXE36_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0779033.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21993..23030)
                     /locus_tag="VXE36_000682"
     CDS             complement(21993..23030)
                     /locus_tag="VXE36_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0779034.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAVTTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23031..23384)
                     /locus_tag="VXE36_000683"
     CDS             complement(23031..23384)
                     /locus_tag="VXE36_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0779035.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23628..24518)
                     /locus_tag="VXE36_000684"
     CDS             complement(23628..24518)
                     /locus_tag="VXE36_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0779036.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGIFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     VSLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24651..25187
                     /locus_tag="VXE36_000685"
     CDS             24651..25187
                     /locus_tag="VXE36_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0779037.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            complement(25353..26159)
                     /locus_tag="VXE36_000686"
     CDS             complement(25353..26159)
                     /locus_tag="VXE36_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0779038.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSETMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26503..28023)
                     /locus_tag="VXE36_000687"
     CDS             complement(26503..28023)
                     /locus_tag="VXE36_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0779039.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENVIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28016..28744)
                     /locus_tag="VXE36_000688"
     CDS             complement(28016..28744)
                     /locus_tag="VXE36_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779040.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28759..29523)
                     /locus_tag="VXE36_000689"
     CDS             complement(28759..29523)
                     /locus_tag="VXE36_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0779041.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29527..29970)
                     /locus_tag="VXE36_000690"
     CDS             complement(29527..29970)
                     /locus_tag="VXE36_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0779042.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30652..30948)
                     /locus_tag="VXE36_000691"
     CDS             complement(30652..30948)
                     /locus_tag="VXE36_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0779043.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(30970..32034)
                     /gene="pepA"
                     /locus_tag="VXE36_000692"
     CDS             complement(30970..32034)
                     /gene="pepA"
                     /locus_tag="VXE36_000692"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0779044.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32435..33136
                     /locus_tag="VXE36_000693"
     CDS             32435..33136
                     /locus_tag="VXE36_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV0779045.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRATVD
                     NRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33559..34518
                     /locus_tag="VXE36_000694"
     CDS             33559..34518
                     /locus_tag="VXE36_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779046.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            34508..35464
                     /locus_tag="VXE36_000695"
     CDS             34508..35464
                     /locus_tag="VXE36_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0779047.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            35461..36213
                     /locus_tag="VXE36_000696"
     CDS             35461..36213
                     /locus_tag="VXE36_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779048.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36309..37274
                     /locus_tag="VXE36_000697"
     CDS             36309..37274
                     /locus_tag="VXE36_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779049.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37499..37741)
                     /gene="yidD"
                     /locus_tag="VXE36_000698"
     CDS             complement(37499..37741)
                     /gene="yidD"
                     /locus_tag="VXE36_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0779050.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37741..38463)
                     /locus_tag="VXE36_000699"
     CDS             complement(37741..38463)
                     /locus_tag="VXE36_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0779051.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38450..39019)
                     /locus_tag="VXE36_000700"
     CDS             complement(38450..39019)
                     /locus_tag="VXE36_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0779052.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39038..39766)
                     /locus_tag="VXE36_000701"
     CDS             complement(39038..39766)
                     /locus_tag="VXE36_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0779053.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39766..40506)
                     /gene="xerD"
                     /locus_tag="VXE36_000702"
     CDS             complement(39766..40506)
                     /gene="xerD"
                     /locus_tag="VXE36_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0779054.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40497..40958)
                     /locus_tag="VXE36_000703"
     CDS             complement(40497..40958)
                     /locus_tag="VXE36_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0779055.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(40955..41476)
                     /locus_tag="VXE36_000704"
     CDS             complement(40955..41476)
                     /locus_tag="VXE36_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0779056.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41452..42423)
                     /locus_tag="VXE36_000705"
     CDS             complement(41452..42423)
                     /locus_tag="VXE36_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0779057.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42420..43214)
                     /gene="racE"
                     /locus_tag="VXE36_000706"
     CDS             complement(42420..43214)
                     /gene="racE"
                     /locus_tag="VXE36_000706"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0779058.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(43421..43669)
                     /locus_tag="VXE36_000707"
     CDS             complement(43421..43669)
                     /locus_tag="VXE36_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0779059.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43925..45550)
                     /gene="treC"
                     /locus_tag="VXE36_000708"
     CDS             complement(43925..45550)
                     /gene="treC"
                     /locus_tag="VXE36_000708"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0779060.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45728..47695)
                     /gene="treP"
                     /locus_tag="VXE36_000709"
     CDS             complement(45728..47695)
                     /gene="treP"
                     /locus_tag="VXE36_000709"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0779061.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVIAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPTADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            47880..48590
                     /gene="treR"
                     /locus_tag="VXE36_000710"
     CDS             47880..48590
                     /gene="treR"
                     /locus_tag="VXE36_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0779062.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        14341 a        11016 c         8975 g        14335 t
ORIGIN      
        1 agaatacttg catcatcctt ctttccatag attggatcaa tagcagaaga attaaatctc
       61 atcttaatta actcttcaaa agttttattt tgattatttt gatagaattc ataaaagcca
      121 tcgctcatta aaacaatttg ttcactagta acatctattt gattaataat agcatggtct
      181 aaaaatctct catccaacga acctatccag tacccactcg gttgattaga taattttctg
      241 attttttgta aaataatttt tttatttaaa acactatttg taccaattga atcttttatc
      301 tcatttttcc ctttttcaaa taagttatct actctatgat cagttatttc catttcgttt
      361 actaacatga cgcagtcacc tagcatcata tactccaact ttttttctga aagtttagca
      421 aatattggta agcgataata tagtatgttg aaactagaat agtacacctc tacttctaaa
      481 acattgttag aaatcgattt gactgtcctg attgatttgt cctattatta tttcatttta
      541 ctatactctg ttaatttata tgagtttaaa ccgatttcat ctttaacctc gagtaaagca
      601 gtttcaaata tttgtttaag agtttttgat tctttacaat taaccgacaa actttctgat
      661 aaaatatgta caacttctga gactgaataa cctatctcct ctttagaatt atataaatct
      721 gtagctccac caataatcca aaaatactga ttttgtgaac ctacaatatc ctcattttct
      781 acggaacttc cttgtatcga acaaatttta tttatcttta ccataatact tcaacccttt
      841 tagtgtcaaa agtaaaccaa ttcctgtcac tgttaagaat agttccataa tcttgttcga
      901 accagtcttt ggtaattttt gttttacatc tactatttct ttagatttat taatatgatt
      961 ttcagtttct ctgccatctc caactatttt atagtttact tcttctgtct tattatcttg
     1021 tttattgtcg atcttgtcat tcatttgtct attatcttta cttgagttaa actctccgtt
     1081 cttctggtta ctatcaatta cattatttga attagattgt ttttcctctt tgtttttttc
     1141 tttttcgttt ttatcactta aattatttgt tacaatattg aaattaccat cgctatcacg
     1201 tataacaggt tctttcccat ttgcattaga tttgatgact gatatatact taccggataa
     1261 attataaaat tggttattta aaacggttat tttacccttt gaatcctcaa taacaattcc
     1321 ttctttacca ccgaatatac tattctctga gactactaaa ttatcactaa ctcgtaataa
     1381 ttcaatattt ggttgttctg tttccttaga attattatta attacatttt ttgttacagt
     1441 aatatctgat acttttccta aatattctgc actatctttt gcaactcgta tcgcttttgt
     1501 tttaggatcg gcaatattaa atatattttc ggcgataacc acctgtttat ttaaatctaa
     1561 taggtcttta gtgtttttat agctataagc atttactaaa gctgctccgt tttctcgata
     1621 atgtacactc tctcctttaa ctttcttatc aaagcgattt cctttgatta atacatcagt
     1681 gaatcctgta aaacgtacac ctgcatacat catgttatca aaatgattat ttaaaatttt
     1741 aatattagag gggttctgtg tcgacaatgt ttgatagtgt gtaccaattg ctgttactaa
     1801 ttccccagat ttatcacttt tgccaaaata ggaattttga atagtcacat tttcagattt
     1861 tttcccatca tcattcaagg cataaggaaa accttttcta gttaatggtt caatctgaat
     1921 gctctcctta cttatgattt gcccatcctt catcgttttg ggtaaggctt gcccaagaaa
     1981 acgagaatta tcaactaata catttttcga acctgcaatt tgaatagcat gcccttgata
     2041 actatccttg aatgttacat tttttatagt tacgttattt gaattcccaa tagcaaatgc
     2101 acctgaagaa tttataagtg gtagattttt tgctttagtt ccttcttcat tcaaagcacc
     2161 gttcatatca atcgtaccac cagaataact aatatcttct attgggcccc attctacttg
     2221 cgcaccatca tccgtaaata aacctgtcat aaaaacaatg gaagggtgat tcttaatatt
     2281 tataccattt agaattgtag ctttctcatt caattctaag tgtgtatgac tttttaaaaa
     2341 aacaatttct tttactaaat aagttccttc aggaaaatat acatttcctc cacctagccc
     2401 ttgagctgca gcatctattg catcttgaat tgcttgtcga tcatcatgaa tcccatcacc
     2461 tactgcacca taatctttta cacttaaagc agtatcttca aattcttttt tgataattct
     2521 gtcacttata acatcttcct tataactctt attttcatta gtagatgtta ctgtagattc
     2581 aactgttctg ttgtctaatt gtgaattgga acgaatagta ccattagagc tgatactatt
     2641 aacacttaac gaattatcta aaccattagt ggttgaatta gaggcaatca tttcagcaga
     2701 acgattctga ttaacagttg gtgaattatc taaatcatta gtaattgcat tagaagactc
     2761 ttttgtagcc atcggtgaag aactagtaac aacttcatcc gataaaatac cttggcttcc
     2821 caaaattgaa attgccaata gtaccgagca agtccccacc tttaatttac gaatactgaa
     2881 tacctcatta ggaacaaaat atttcatcag aacctccaat ttttttacta tttttaacaa
     2941 ttgattatta cttttcttaa aatagataga atgacaccgc tgtcattatc tttatcatat
     3001 attttccaaa ttgaattgtc aaggaataac acaagaaaat attaaaattt atactcttcg
     3061 gaaatctctt caaactaggt cagtgccgcc ttgccctaag tctaggttac tgacttggtc
     3121 agttctatag tagactgaaa ctataatagt acacctctac ttctaaaaca ttgttagaaa
     3181 tcgatttaac tgtcccgatc aatttgtcct attcttgttt cattttacta tatctacaac
     3241 ctcaaagcag ggttttgagc tatctatggc caacttccta gtttgctctt tagccttcca
     3301 ttcaaaagtg atgctatctt tcttagcttg aatataaaat atcccattta ctatatttaa
     3361 atttgttgat atgttgtaaa ttataaatga aagaacaaat accttgtcat acaagcattc
     3421 gccagggata tttacctgaa tatcgctcat atggcggatt gaaactaaaa cactacaata
     3481 tatttcttaa atagaccttc tataaaagct agatttaacc tcgataaaaa tagatgcagt
     3541 gcttctaaaa tactggaata gggcatatag gtaatcgtag acaagtgttt tatagattgt
     3601 ctcgcaggag atctaataat gtatagcaag catcactaaa catatagaat atttgtatta
     3661 ttataatatc aacatgctat aaattctatc atgcaaaaga atgactagaa catgaaagac
     3721 aggcacaaaa ttttgaacaa tattctgaaa acaaaaaaag acgcgagttt ccacaatctc
     3781 actcatggaa actcacgtct ttcaaaaaat agggtgaatt gaaaactaga acaagacact
     3841 agattttcta aatgatgtct agtaaggatt ctaaatgcta cactaaattg ctcacatctt
     3901 atttcaaacc acgggactcc cacaagaaag gaaaatccta taaaaattct ctctctgagg
     3961 agaaagaggc ctcaactaca ggtgtaaact attatcaatt gaaaacaaca gtttttacac
     4021 tcaattagac tttttaggga caggatcact ttcgcttgac tgtagtttgt catttttttg
     4081 ataaagttag cactttttca gaaactgttt tgaaagtctc aatgatatag tctacttctt
     4141 catcgcttaa tttagtatga agagggaggg taatttcatt ctcaaagaag gcataggcct
     4201 taggatagtt cgtcatatca aatccaagat tcttataggc tgtcaagaga ggaagcggtt
     4261 tgtagtgaac attacttgca attcctgctt tagccaattc ttggatgatg aggttgcgtt
     4321 cttctaggct tgctccttct acacgggtga tgtagaggtg gcgtgaagat tcgacagttt
     4381 cagtcttgtg tgccaaagga tggatgcgag aacctacaaa accactatca tagcggtcca
     4441 caatgtcctt acggcgttgc aacaaacttg gatagcggtc caattgtacc aaaccaagtg
     4501 aagccatgat atcggtcatg ttgcacttat aggctggtgt aacgatatcg tattcccatg
     4561 accccaattg catcttggca agagcatcct tagtttgccc gtgaagggaa aggatttgga
     4621 attccttgta catctcttcg tcatcaatca ctggattggc tttccaagtc gcacttccac
     4681 cttctgccgt tgtaaagttc ttaacggcat ggaatgagaa ggaagtaaag tcagcgatag
     4741 aaccagaagg ttgtccttta taagtagatc ccaaagcgtg ggcactatca gagacaatga
     4801 caatacggtt aaaggccttt tgccacttgc ttgaagcggt aaagaagtca cgttttttct
     4861 ccacgacttg gaacaaacgg tcataatcgc aaacaatccc tgcgagctct actgggataa
     4921 tcaccttagt tttctcagtg atagcttgct caagcaggtc atagtccatc tcaaacgtat
     4981 ctgcttggat atccaccatg acaggggttg ctcccacgtg cgtaatgaca ctacatgaag
     5041 ccgtataggt catggctgga acgatgactt catcaccagg tcccacttcc aaaacgcgta
     5101 aaatcaactc cagagcggct gtcgcagagt tgagacaaac agtcttaggt gtctgtgtgt
     5161 aaagagacaa gcggcgctcc agttcttttg ttttaggacc tgttgtgatc caaccagaac
     5221 gcagggtatc cgctacttca gcaatttctg cttctgtgat atcaggcggt gaaaatggaa
     5281 tattgtaatt tggcattgat ttgctccttt tatctgtact cattttctta tgactacttt
     5341 attttagtac ctcaaacacg gtttgaaaca tgattttgat gtccccaaag aaactaaact
     5401 ctcggagata ggcgaggtta tagcgcatct tttcaggaag aacatgctcc acataggcct
     5461 gatcaactga cagacctttc tccgtcattt gactgatgat ggtgtcctca tccttgtagt
     5521 tgatgctggc tggagaggta attcctgctt gcaagagcaa ggttgccatc atttcagggc
     5581 tatactgctc tgtataacgt ggcacttcag gtcgtgtacc gacaaaggac atctcacctt
     5641 taaggacatt gaccaactga ggcagttcgt ccaaacggac acgtcggatg aaatttccaa
     5701 ccttggtaat acggctatcg ttagcagaag tcaccagact tcctttttta tccgcatccg
     5761 tcaccatggt acggaacttc caaatcttga accgacggtt gtactgggtc acacgctctt
     5821 gcttgtaaat cactggcccc ttgctatcca acttgatcca aatgctcaag atgagaaaga
     5881 tgggagaagt tagaaccagt aagaccaagg ccaaaaccca gtccaagcaa cgcttgaaaa
     5941 tcagcgaacc cttcctttta gagacaagct ggtagtaaga ctcaacctcg cttgatttca
     6001 tttccacagg caagtcttcc catttcagca tgctgttctc ctttgttttt attatactat
     6061 ttgtcaacat ttttcattat accacaaaat ggaaaaggcg gtgaaagaaa tctgtaattt
     6121 gaaggatttc cttctagtac tcaatgaaaa tcaaagtaca gctttgagat tgcagataaa
     6181 gctgacatgg tttaaagaga ttttcaaaga gtataggcca tggcccctgc ctgcaaacta
     6241 tacatcttgt gataggttcc tcccagagtc aagaggtcct catgggttcc actctcgata
     6301 atgcgtccct tatccaagac atagatgcag ttggcgtctt gaatagtaga aaggcggtga
     6361 gcgatagcaa tagttgttcg gccctgtctc atcttcgcca gagaagcttg aaccaaactt
     6421 tctgtttcag agtcaatatt ggctgtcgct tcatccaaaa tcaggatttt aggctggctg
     6481 gcgactgttc tagcaaaggc aagaagctgg cgctgcccag tagagaagct cgaaccacgc
     6541 tcggaaacag gggagtcgta cccctgagga agttcttgaa taaaggaatc tgcatccaca
     6601 aaggctgccg cagcctgaac ctgctcatca ctgatttctt ggtacatggc gatattggac
     6661 ttaatagttc catgatagag gaagggttcc tgtaaaacca aaccgatgtt ttttctcagc
     6721 tcttcttgac tgaaatccct gatatccaca tcatccaaga gaactctccc tgactggaat
     6781 tcataaaagc gcatgaggac attgataata gacgatttcc ctgaacctgt atgacctaca
     6841 aaggcaatgg tttcaccctt attaacagag aaagaaatgt catccagaat cggatgttta
     6901 ccgtcatacg agaaacacac atgttcaaaa cggatattgc cttctttgac tttggcttgc
     6961 ccattttctt gaaggggctc ataggtcctc tcatcgatta aggcaaagac acggcctgca
     7021 gaaaccatag acgtttgcag tgttgaaaag ttttgcgtca cctcaatcaa agggtcaaag
     7081 aggcggttga tgtactggat aaaagcatac atggtcccgg ccgttatccc gatagaaaga
     7141 ccacggtagc caaaataggt catcaagaca gcataaccta gaagtttcaa caaactcatg
     7201 gcaggtctca aaaagagggc atccaaggct acagaacggt tggcataggc caagtgctct
     7261 tggttgattt catcaaattc tgcctgcagg cgcttctctt gattaaaagc ctgaataatc
     7321 ctgattccct cgatattctc tgccagctta ctattgatat ctgacaagag acttctggtt
     7381 ttctcgatga ttttcactga cttttttcga tagagattga ccaaaaggaa aatcaagggg
     7441 agaaagagca agactaatgc tgtcaaacga aaatccagca ccaacatggt ataaagggtt
     7501 gtcagaaaga taaaaactgc tgagataaag ctggataaaa tcccagaaaa catatcacta
     7561 atcgtctcgg tatcgttggt caaacgagaa acgatagaac ctgctggcgt cttgtcaaag
     7621 taagacatgc ccagtttctc catattggca aaggcatccc gacgaatatc cctaacaata
     7681 ctgtaagaca cgcgtgcaaa gagaagattg ccgacatact gaactacagt ttgtaggatg
     7741 tagagaccat agtagaccag caaaacggtc acggctagtt ggttaagatt gctgagatac
     7801 tggtcgataa agtgggaagc cacgaggggt atgacacttt taatgaccgt cgtcgctagg
     7861 agaaagctga gtgccaaaaa ggtcaggagt ctataaggct tgagatagga catcaagcgc
     7921 ttcaatacag tccattgttc ttgtttattc tgcatcttct tctcccttca tttccagctg
     7981 ctgagactgg taggtttggg cataccagcc atccaaagct agcaagtctt cgtgcctgcc
     8041 tcgttcgata atttgaccat tttgcaggac taaaatcaaa tctgcatgga caactgcact
     8101 caggcgatgg gcagtgataa tggttgtctt gtcctttcgc gtctccttga ggttgtcgat
     8161 aatcgcatac tctgtcttgg catctacggc ggataaggaa tcatccaaaa tcaagatatc
     8221 agggtctaaa atcatagccc gactcatagc caaccgttgc ttttgaccac cagaaagact
     8281 gactcctttt tcaccaatca gcgtatcaaa tccttgaggc atgtctacaa tatcttggta
     8341 aactcgggct agcttagtag cttcctcgac cgctgaaagg ggcaagttag gattgccaaa
     8401 gcggatattg tctaggattg aagtcgcaaa gagaaactgg tcctgaggaa catagcccat
     8461 gagactgcga aggtctgtca gacgatagtc ccgaatatcg tgaccgttta gataaatggc
     8521 acccttatcc acatcgtatt cacgcaagag gagcttgatt aaggacgttt tcccagagcc
     8581 tgtctgccca accaagccca gggtttgccc ttttgccaaa ctaaagtgaa tatccgtcag
     8641 tgtttcctca ttttcaaaag caaagctgtc aatggcatac tccaaacgcc cattttcaat
     8701 accatccaga ggaaactcag ggtcttgtac aggagattcc tgagacaaaa gattttcaat
     8761 ccgctggtaa gaaaccttcc ctcgctgagt agtattaaag aggaaaccga tggccagaag
     8821 aggccagacc agcatatcca aatagctgat aaaggtgact agattcccaa ctgtaatctg
     8881 cccttcctga accatcaagg agccaaccaa aagcgttaaa acataggacg aaccaacaaa
     8941 caagagaacc atagggtcaa agagactatc atatttcatg gtttgcaggt tcttttggaa
     9001 ggttaattca ttgactgcct gaaaagactt caactcgtct gcctgataac cgaaagactt
     9061 ggtcactttg atacctgata cggactcctg taccttgtta ttgagttcag aaaaagcagt
     9121 ttgggattcg ccaaaggcct tatgagtctt tctccctatg cgactagtcg cataggccat
     9181 gaaaggtagg gggagaatgg caacaagagt catctgccat gagatgctaa agagcatggt
     9241 caacaaagtc accagagccg tgatagaggc atccaccgca gacatgacac cgccacctgc
     9301 taaacgagtc aaggcattga tatcattggt tgcgtgtgcc atcagatcac ccgtccgata
     9361 ggtttgataa aaggctgacg acatttttgt gaaatgctta aacaagcgag accgcatgat
     9421 ctgtcccaag caataagagg tcccaaggat atacatacgc cacacatagc gcaaatagta
     9481 cataccaaag gctgcaagta gcaagtaaaa taggctaaga aggaggtcct gctgggttaa
     9541 ttgccccgat gtgatggcat caatgacccg ccccataacc ataggaggaa tgagattgag
     9601 gacggaaacc aagaccaggg ccacaatccc gactagataa cggcgttttt ctaacttgaa
     9661 aaaccaccaa agtttttgaa taatggacat aaaatccctt tctgattgca aatggaagcc
     9721 tgaggccaat actcaatgaa aatcaaagag caaactagga aactagccgc aggctgctca
     9781 aagcactgct ttgaggttgt agatagaact gacgaagtca gtaacctaca tacggcaagg
     9841 cgacgttgac gcggtttgaa gagattttcg aagagtacaa gaccccaggt ttttcttatt
     9901 cataagttac gactgtaaca gcacccttgt catattcagc aataaagata ttggctacat
     9961 tgtcatgccc ttgtttgctg aggttatcaa gcaaccactc ttcgctacga ccaatcgatt
    10021 ccaagacatc tacttgaatc acaccgtcag tcacaactgg atacttagga ttttcatctc
    10081 ccatttgcac aacgatgagt tgcccatttt gctcttgcac agctcgtttg acttgcttca
    10141 tctggaaaat cccttggcta cgaagtttga gggctacatc cgatgcagac aaaccaactg
    10201 aacgacaggc ttatgggtca atattcccat ttttgataag gagagttggc ttaccatcaa
    10261 tcaaacgttt cacaaagtga acattgttgt tgagccattt gagagtcaag accagtttga
    10321 ttaaaatttc gatataatta agtgtcattt gttcacatcc accagttcaa ttgcgtctgt
    10381 cttatacaat tcgactttct ctaacaggta cttgtctggc tcacttccgt ttagggcacg
    10441 ataatagcga tctcccacct tgataagtgc gccatctgtg tttgtggaag tattaacata
    10501 gacttctgac ttgtctactc ccaaatcttt ggaaacaacc tcgatgaaat gaagtgaagt
    10561 ttgaaattta ttgttagaaa cttgattgtt ttgataagtc gtgatgctga ccaaaagcag
    10621 agctaaataa ggccagagct gaaatcatga ccaactcacg aaattcggtt ccctttttat
    10681 catggtatgc cttgaaagca aaaaaaactg tcacagctaa tagaacaatc ccaaagccaa
    10741 ccatgatacc attttgctga ccgatttggc tgagtacata gtcataagag tagaatttca
    10801 tatattttca ctccctttca taaaatcatt cttaattata aacgaaagag agtaattttt
    10861 caaaccatac gttggggaaa tagatctttt tttggtataa taaaatctat aatctgaatg
    10921 aaaaaggtaa ctttatgaaa cttatctcat ggaatattga ttccctaaac gctgccctaa
    10981 ctagtgactc agctcgtgcc aaattgtccc aagaagtcct acaaaccttg gtcgctgaaa
    11041 atgctgatat cattgctatc caagaaacca agctttctgc caaaggacct acaaagaaac
    11101 acgtggaaat tttagaagaa ctcttcccag gctacgaaaa cacgtggcgc tcttcccaag
    11161 agcctgcccg taaaggctat gctggaacca tgttccttta taagaaagaa cttacaccta
    11221 ctatcacttt cccagaaatc ggtgcccctt ctaccatgga cttggaaggc cgcatcatca
    11281 ctctagaatt tgatgcattt ttcgtgaccc aagtttacac accaaatgct ggcgatggtc
    11341 ttaaacgctt ggaagaacgc caagtctggg atgtcaaata tgcggagtat ttggctgaac
    11401 tagacaaaga aaaaccagtc cttgcgaccg gtgactacaa cgtagcccac aatgaaatcg
    11461 accttgcaaa tcctgctagc aaccgccgtt cacctggatt tactgacgag gaacgtgctg
    11521 gatttaccaa cctattggca actggattta ctgatacctt ccgccatgtt catggcgatg
    11581 ttcctgaacg ctacacttgg tgggcacaac gcagcaaaac ttctaaaatc aacaatacag
    11641 gctggagaat cgactactgg ctcacaagta accgtatcgc tgacaaggtc actaaatctg
    11701 atatgattga ctcaggtgct cgccaagacc atacaccgat tgtcttggaa attgacttgt
    11761 aaggattttc tatatggact acaatgcggt cattcccgag tttcttgtat cgaatatcga
    11821 acagtcccgg tccttctact gtggtttact gggttttagg attgaatacc aacgtccaga
    11881 agaaaacttt ctctttctct tgaagagtgt caactaatgt tagaggaggg aacaaaggat
    11941 caactagctg aactgaccta cccctttggt cgtggagtca atctctcctt tggcataaag
    12001 gatgttccaa aactctatca aaaagtgatg gaggcaaact atcctattta tcgtcccttg
    12061 accaaaagaa agtttcgtgt cagtgatccc tatatctatc ctcataaatt tgcagttttg
    12121 gatccagatg gctatttttt aagatttagc gagtagaata ataaaaattg ggaaaagtct
    12181 ttaaagttag aaaaaggcat attgtcaggt gtctaaaaac ttgatagtat gccttttatg
    12241 atggaaaaat cttctaatac tcttcgaaaa tctcttcaag ccacgtcaac gtcgccttac
    12301 cgtaggtata tgatactgac tctgtcaatt ctatccacaa cctcaaaaca gtgttttgag
    12361 gttgtggata gcttcctagt ttgctctttg attttcattt agtataaatg ttagcttaca
    12421 atggagtttt tattcaccct ctcttctgtt tgttcgtttt ttaaaccgaa acactaacaa
    12481 aatagttgat ttttaaagtt atttagtgta aaataaaaac attggctcaa gcctatttaa
    12541 aattgaatat cgttttactt gtttatgtcg tgaattggca cgacgtttct acaaggtgcc
    12601 ggaacaccta acaataagta agtcagcagt gagatatggc cgtttttgcc atgcctattt
    12661 gggggactta cttagagatt aagtaggtct tttttgaata tttttaatat ttcccttaat
    12721 tagtgcggac gggaggtgaa attatcctgt gaataatttc aggaatccag ggaatttcat
    12781 ccctaatttt tgagccccta gctctttcat ttctaggctt aggctaaaat agttccccga
    12841 actattttac tctcaaaaat cccgtcatag acaataacaa gattattgtc tatgatacca
    12901 ctacaacggg aaatatttga taagactcgc ttcgctcgta atagttttat caaatatata
    12961 atattagcaa aagggatcac tatagaaaca tttaaacaac aagtaaatta acttttagac
    13021 tttaggaggt cttatgaaat tattagaaga gcgcatcctc aaggatgggc atatcttggg
    13081 tgataacatc ctcaaggtag attccttttt aacccaccaa gttgacttta gcttgatgcg
    13141 agagattggt aaggtttttg cggaaaaatt tgctgctgct ggcattacca aggtcgtaac
    13201 cattgaagcg tcgggtattg ccccagccgt ttttacagct gaagccttaa acgttcccat
    13261 gattttcgcc aaaaaagcta agaacatcac catgaacgaa ggcatcttaa ctgctcaagt
    13321 ctactccttt accaagcagg tgaccagcac tgtttctatc gctggaaaat tcctctcacc
    13381 agaggacaag gttttgatta tcgacgattt ccttgctaat ggccaagctg ctaaaggctt
    13441 gattcaaatc atcgaacagg ccggtgccac agtccaagct atcggtatcg tgattgagaa
    13501 atccttccaa gatggtcgtg atttgcttga aaaagcaggc taccctgtcc tatcacttgc
    13561 tcgtttggat cgttttgaaa atggtcaggt cgtatttaag gaggcagatc tctaatgcaa
    13621 actcaagaaa aacactcgca agcagccgtt ctgggcttgc agcacttact agccatgtac
    13681 tcaggatcta tcctggttcc catcatgatt gcgacagccc ttggctattc agctgagcag
    13741 ttgacctacc tgatttctac agatatcttc atgtgtgggg tggcaacctt cctccaactc
    13801 caactcaaca aatactttgg gattggactc ccagtcgttc ttggagttgc attccagtcg
    13861 gtcgctccct tgattatgat tgggcaaagc catggtagtg gcgctatgtt tggtgccctt
    13921 atcgcatctg ggatttacgt ggttcttgtt tcaggcatct tctcaaaagt agccaatctc
    13981 ttcccatcta tcgtaacagg atctgttatt accacgattg gtttaacctt gatccctgtc
    14041 gctattggaa atatgggaaa taacgttcca gagccaactg gtcaaagtct cttgcttgca
    14101 gctattactg ttctgattat cctcttgatc aatatcttta ccaaaggatt tatcaagtct
    14161 atctctattt tgattggtct ggttgttgga actgccattg ctgctactat gggcttggtg
    14221 gacttctctc ctgttgcggt agctccactt gtccatgtcc caattccact ctactttggg
    14281 atgccaacct ttgaaatctc atctattgtc atgatgtgta tcatcgcaac ggtgtctatg
    14341 gttgagtcaa ctggtgttta tctagccttg tctgatatca caaaggatcc aatcgacagc
    14401 acgcgccttc gcaacggata ccgcgcagaa ggtttggccg tacttctcgg aggaatcttt
    14461 aacaccttcc cttacaccgg attttcacaa aacgttggtt tggttaaatt gtcaggcatc
    14521 aaaaaacgcc tgccaatcta ctacgcagct ggtttcctgg ttctccttgg actgcttcct
    14581 aagtttggtg cccttgccca aatcattcca agctccgtcc tcggcggtgc catgctggtg
    14641 atgtttggtt ttgtatctat tcaagggatg caaatcctcg cccgagttga ctttgctaac
    14701 aatgaacaca acttccttat cgcagctgtt tcaatcgctg caggtgtcgg tctcaacaac
    14761 agtaatctct ttgtcagcat gccaacagcc ttccaaatgt tcttctcaaa cggaatcgtc
    14821 gtagccagcc tactcgctat tgtcctcaat gccgtattaa atcataaaaa gaaataagaa
    14881 aaagaggtgc gagcctcttt tttgtttatc acaaattgat tataaataca atcaatccca
    14941 attcccatct aattgaattg gacctatttc aaattcttta aaatattatg ttccaaatcg
    15001 ttaatattat ataagaatgg taaaatatca aatgtttctc gtaaattatt cttagcctta
    15061 taccaacctt gtccatcagt aatccacata aactcaacat taggaatagc tttaatttct
    15121 tcagcaatca ttttgtaaga tctagccgtc tcatttaatt ttgaaccact tcctgaataa
    15181 aaattaacct caatcagata aagcacttgt tcatttttta tgacaaaatc aaaacgtttc
    15241 acagtattcc catcattcgt aatagcagat aaatcgacag aaaaaatttc ctctatttca
    15301 ttttgttcaa tctctttaaa taaattctct cctaaaatat acccttcagc ttcaagataa
    15361 ctttgaacaa tattttccat cgcatctcca gtccgatttt tgcgcccatt agtatccata
    15421 ccaacctcaa cacctgtaac gtagtcaact aaatttgata ctaaatgatt ttgcaataaa
    15481 tcaaatatac ctgatttttc caaaaacata gtatattctt caatactata gtttcgttta
    15541 ctaaaatcaa aatagaaatc ttttatcgga tccttaacaa taatcgtatc tctcaaacgt
    15601 ttagcaataa gtagaggcac aactttcaaa atttctggat aattttgata taagtctaaa
    15661 aaatcctctt gtatattttt actaccaata agactattca taatatttag agcaactttt
    15721 atactagata catttttata aaccttagga aaatctgtat aataagtcca gtcagctact
    15781 gtgtcggtca tcgttgacaa ccactcatca aaatttctag tttgtttcat tttctgcctc
    15841 caacctcttc cttgcaattt ttaaatattc tttttcagca tcgataccta taaatcttct
    15901 acctaaccgc ttcgcaacaa cacccgtagt gccactacca acaaatgggt ctagaatata
    15961 gtcaccctct ttagtagagg ctaaaataat gcgttctaac aaatactctg gtttttgagt
    16021 tggatgtttc ccagcccatt tttcaacttt ctttgttaaa gaaccggtcc agacatcttt
    16081 catttgtttt ccatcattca attctttcat taaatcataa ttgtagtaat gacgagcttt
    16141 tttatcattt tttctggccc ataaaatggt ttcagtagaa tgggtaaaat aacgacaaga
    16201 taaattgggg gcagggtttg ttttctgcca agtaatatta ttcagaattt taaaaccttc
    16261 ttgttctaat gccattccaa ctgagtatat gttgtgcaaa ctacctgaaa tccataccgt
    16321 cccattaggc ttcagaactt cttttgctag gcgaatccat ttacgattaa actcatgttt
    16381 ttcttcgaat gaagaaattt tatcccaatc tcctttatca acagaaacaa cttgtccccc
    16441 agaattagat attccaccat tacttaaaaa ataaggtgga tcagcaaaaa tcatatccat
    16501 actttctggt ttcatttttg ataagaactt gaacgtatct gaatgaacaa gaatcatctt
    16561 atttttattg tagtatggtt ttgtcataag aacacctcca tacttatatt cgttattttt
    16621 cataatttgt gactataatt tcagaaattt ttcctcgact tgaagatttt gctccattag
    16681 ttcgggtagc ttcaacataa tgtatattaa aatccttata caactcctct actaaagcac
    16741 tagaagaatt tgataacata acataagctc ctgtatcact caatctctta aaggcatctc
    16801 ttaatcttac ttgatctgca aaagagaatc cctcatgagt ataagacgta aatgcactcg
    16861 tctcagacaa tggaatatat ggagggtcaa aatacacaaa atctcctgtt cgaacatcta
    16921 caattgcctt ttcaaaatct cccactttaa tttctagttg attgttattt agataaactg
    16981 aaatagcaga tatcaattcc tcatcaacaa ttttaggatt cttataacgt ccatatggaa
    17041 cattaaattg gttcttagaa ttcacacgat atagaccatt aaagttcact ctcaacatat
    17101 atagaatacg tgcagctctt tgtacttcgg acatcatatc tattctttca tcacgatctg
    17161 cagaacgtaa atctaaataa tattcttttg aattatattc ctgatgaact ttcaaaattt
    17221 caatcaattc ttgaggattg tccttaattt gttgatagca atttattagt tcagcgttaa
    17281 aatcattaat aactgcatct ttaggagcca aatcaaaaaa taaagctcca cctccaacaa
    17341 aaggttcgaa atacctgtta taggttttag gcattaattc tctaataaca ggcaataatt
    17401 gtcttttacc acctgtccat ttcgtgaacg gttgtaaagt aactttcttt atttctttta
    17461 tcttcatgct tttaattata ccatagaaat taaaacacaa ctcttgtatt ttctaccaca
    17521 ttactaaatt ttctatttta gaattaaatc atatcaatat caaaaaatga gtaaggcaaa
    17581 tcttataaat tccaaaattc acctcactct attaaattac tctttatata cttacccgtc
    17641 tttcttctga cctttggcct gtgacaaaca tggtaaaggt tgctttacag acatttctgc
    17701 cctcttgatt ggtgatatac acatccatca cacaggttgt acgaccttga tggacacatt
    17761 ctcctttaat ggtcaataca tcgtcgagtt ttcctgcctt aaggtagttg atagaggatt
    17821 ggagtgtcac cccatcaagt cccagcgaga taaccaccaa accactgatt tggtcacata
    17881 gcgtgaatag atagccacca tgggcattgc catagtagtt gagcgacgag ttcactactt
    17941 tggtcgtcac cacaacgtga ccatctctca ttttttcaat ttcgtaattt tcaaaggcag
    18001 atatagcgtc aaaatgaaag tctttcatcg tttcctcctg atatttcaaa cgacactatg
    18061 atactacttt ttataggact gtgcaaggag aaagctccta gtctagtgaa attccgacct
    18121 gttccacaaa gcgcataaag gctgtctgcc cttgttctgt ctgcttgtag actcctgcat
    18181 cctcaagtac acgcacaaag atagcaccca cagagtcctt gacgattgca agggcttttt
    18241 ctttatccgt taggtctgga tgttgggatt tgagttggtc tgcccactcc tgatgataat
    18301 cggcaactgt aacagcttct cctacaagat agctagcgac ttgctccact tcttctttca
    18361 gacgtggtgg caagattgcc aagcccatga cctcaatcaa gccgatattt tccttcttga
    18421 tatgttggac atccttgtgg ggatgataga tgccatcagg atgctctgct gaagtctgat
    18481 tgtctcgcaa gaccaagtcc aactcaaact gtccatcacg cttacgcgct attggtgtga
    18541 tggtgtgatg cggtgtcccg tctgtctctg ctaaaatctg cacactagaa tctgaatact
    18601 gacgccattc ctggaaaatc ttatcagcta agttaatcaa atcctctttg gaatccgaag
    18661 tcaagcgtag gacagacatt ggccacttga taattccagc cttgacctgc tcaaaaccag
    18721 caaatcggaa ggtcttttgc aagggagcca attccatagg aaatacgtga cggcctccct
    18781 gataatgatc gtgagttaga atagagcccc ccacaatcgg caggtcggca ttagatccag
    18841 caaaatatcc tggaaactgc tctacgatag ccaacagacg ttcaaaactc tgacgactaa
    18901 tggccatggg acgatgctgg ccatctaaaa agatacaatg ctcattaaag taagcatagg
    18961 gcgaatactg gaacccccat tcctgaccaa ccatttcaaa acggataatc cggtggttgc
    19021 tgcgagctgg gtggttgacc cgaccatggt aaccctcatt ctctaaacaa agttgacact
    19081 gaggataatt actagcttgc accaacttgg ctaccgcaat ctctttcgga tccttttcag
    19141 gcttagagag attgatggta atttcaagtt ctccataatc agatggaaca cgataagcga
    19201 tatttttagc aatggccttg agtttgatgt agtcattttt ctgactgagt tgataaaaat
    19261 cctctatcgc ttgctcagga gagtaggcat aggcttccca gaagtcacga ttgacctgac
    19321 tcggacaagg agtcaccaag tccatcagtt cagtaccaag gatttcacgc gcagtctgac
    19381 tatcctcaat cgtctctaat cgaacggctt cctcaactag ctggtccttg aggtcaatca
    19441 atttatccag attggtctca acttccaaaa caccttctcc cactcgtgcc aaaacacgat
    19501 tggtcaggta gattcgatcc atttcctcaa atgaactttc agaaatgaca tgtgttacaa
    19561 atttatctac taaggtcact atagagcctc cttttgacta gtcaaggacg cgagtgccac
    19621 ctgcaacttc agcgatatag aagcttggag cgtatccaac tacttcctcg tagtgtttgc
    19681 ctacagcttc cttaaaggcc tcaacagtat ctttttgaac caaggcaatg gcacagccac
    19741 caaaaccagc ccctgtcata cgagcaccga gaactccttc ttgtgcccaa gctgtgtgaa
    19801 caagggtatc taattccaaa ccagttactt cataatcatg ctccagagaa acgtgtgacg
    19861 cattcatcaa acgaccaaat gtttccaaat cacctgcttg aagggctgct tgagctttaa
    19921 gggtacgttg gttttcaagc acagcatggc gagcacgttt caaacgattt tcatctttaa
    19981 ttagatagct atattggtca acggcccact cgtccaattc acccagggtc tgaatatcca
    20041 aggcaacttg caattcttcc actgcttttt cacactcagc acgacgttca ttgtatttag
    20101 agtccgccaa ttcacggcgt ttgttggtgt tcatgataac aacgacattg tccttcaaat
    20161 caagtggcac caaatcatac tctaaggtgt tggtatcaag gtaaatagca cgttgatcag
    20221 cccccatacc aatagcaaac tggtccatga taccagagtt gactccgata aagttgtttt
    20281 ctgtttgttt gccgatttta accaaatcga gacgctctaa ttttaaatca aagagatgct
    20341 ctgccacgac tcctgtcaag agctccaagg atgctgaaga agacaagcca gcaccatttg
    20401 ggatattccc ataaacataa aaatcaaaac ctttgtcaat cacgtgccca gcttcttgca
    20461 agaaatgaag aacccctttt ggataattgg tccagttgtg ctctttttca aacttgaggt
    20521 cagcgagagg cacttcgata atgcccttgt cctcaaagtt agctgagtag aaacgcaaga
    20581 cttggtcgtc acgcttacga gctgcaccgt aagttcccaa ggaaatagca gcaggaaaaa
    20641 cgtgcccacc gttgtagtct gtgtgttcac caatcaaatt aatacgacct ggtgaaaaga
    20701 aggtttggtc tgcttcttga ccaaaaacag caagaaagtc tttgcgaagg acttcagtag
    20761 taagatgttg tgccatatga attctccttt gactgtccgt taagccatct taacgtgtaa
    20821 tcgttttctt ctattgtatc caaggaattt cccaaggtca atccttttta ctaaaatttt
    20881 actaaaatat cagtaaaaag aagaaaaata tgatatacta acctaatcaa ggaggattta
    20941 tggctacctt aaaagacatt gcacagctag cctctgtctc aatcgcgacc gtatcccgtg
    21001 tcctcaaccg cgaccagagc ctatctgtta cagaagaaac cagacaccgt attttaaccg
    21061 ttgctgaaga gttaggctac accaaacacc tcaagacagg cgagtcccac aagcccaagc
    21121 aaaagattgc cattatccaa tgggtcagcg aacaagggga gctagacgac ctctactact
    21181 accagattcg cctaggaata gaaaaaagag cccaagagtt ggactacgat atcttgcgct
    21241 attttaatga ccatcctttt accttaagcg aggaagtgat tgggattctc tgcatcggaa
    21301 aatttagccg agctcagatt tctgcctttg aagaatacca aaagcctctt gtatttctag
    21361 acagcgatac actttccctg ggacatacct gtattatcac ggatttttac actgctatga
    21421 aacaggttgt cgattatttc ctcagtcaag ggatggaccg catcgggatt ctaacagggc
    21481 ttgaggaaac aacagaccaa gaagaaatca ttcaggacaa gcgtctagaa aacttcaaaa
    21541 actacagtca agcgagggga atctatcatg atgaactggt ctttcaagga agatttactg
    21601 cccagtctgg ctatgactta atgaaggagg ccattcagag cttgggagac caacttccgc
    21661 cagcattttt cgcagccagc gatagtttag ctatcggtgc cctccgtgcc ctccaagaag
    21721 ctggaatcag cctgccagat cgcgtcagcc tcatttcatt caacgacacc agtctgacca
    21781 agcaggttta tcctcccctc tccagcatca cagtctatac tgaagaaatg gggcgagcag
    21841 gtatggatat tcttaacaag gaagtcctcc acggtcggaa aatccctagc ctgaccatgc
    21901 tgggaaccag actgacatta agagaaagta ccctaaatca agaataggat aacataaaaa
    21961 acgaatagag ttctaaaact cctattcgtt ttttattcga ttacaatcat agacttaatg
    22021 gtcttacgtt catccatatc tttataggcc tggtcgatat cttccagttt ataacttgaa
    22081 gtaaagacgc gacctggatt gatatcacca tcaaggacgg cttttagtaa aaattgctta
    22141 tcgtatgttg tagcagaagc tgccccacct gctacagaga tattttgcat aaatgtcgaa
    22201 ccaagagcac gattattata gtgtgggact cctacaaagc ccatacgccc tccattatga
    22261 agaacaccta gcgcctgttc tatagcagcc tccgtaccaa cacattcaag tgctgcgtct
    22321 gctcctccac cgaggatttc acgcaccttg gtaattcctt cttgaccacg ttctgcaaca
    22381 acagctgtcg cacctgactc catagccatc ttttgacggt cttcatgacg gctcataagg
    22441 ataatttgtg atgctccacg catcttagcc gcgatgacag cacattgacc aacagcccca
    22501 tcaccgataa caacaacctt gtcccctttt tgaacatttg caacacgcgc cgcatgatag
    22561 cctgtcggca tgacatctgc aagagtcaaa agggactgga gcatcccttc tgtatagtca
    22621 gaaggttgac cagggatttt aaccagcgcc cagtttgcat agtggaagcg aatatattct
    22681 gcctgaaaat caccccccaa attattgcca atatgattgt cgcaagaacc gtcaaatcca
    22741 gcaagacagg catcacactc accacatcca tgtgtaaaag ggacaatcac aaaatcacct
    22801 ggtttcaccg tcgtaacggc ttccccagct tcttcaacaa tcccaatcgc ttcgtgtcca
    22861 ctatttttgt gtccagcttt cgtttctgga ttacggtacc tccataaatc tgaaccacaa
    22921 acgcacgcac gaaccacacg aataatcaca tcatccgctt ctattatttg cggacgttca
    22981 atgctagcaa gtccaacctg acctgccttt gtatatactg ctgatttcat ttaaaatttt
    23041 ccttccttat aaagtttaat tttgagattt aaacgattta aagctgtctg tagctgagac
    23101 aagcgctcct ctaatttttg cttttcctct tctaaaatac caagcctctc ctctctcgtt
    23161 tcatctccct tttggtagag cgacatatag tcaactaaac tatctacaga gacacccgcc
    23221 gaacgaaaac acttaataaa ttccagcgct tcgatatcct gatcttgaaa atcacgaatc
    23281 ccagtagcag tacgagtaat cggtggcaca agaccaaccc gttcataata ccgaatcgta
    23341 tccgctgaaa ttcccaacaa atcactggca gatttaatat tcacacgcta acctcctctc
    23401 atttcattca ctgaattcac gctattctaa ctcacttatc ttattatata actttgagtt
    23461 gactccaagt caagcatttt gtatctaatc gaaaaatttt tatcattaac aatcatatat
    23521 ctggagttta tacaatgctc ttctcttacc aatttttgaa atatttaaat aataaagaaa
    23581 ttactctatt ccaaataaga tagtacccaa gtatttttca cttttttcta atgttgatgc
    23641 tcataactcc gttccaagtc acacaccttt cgcttatggg tttggtgagt ttctaggtca
    23701 gcatcaattt caatggtaat attttgaaaa ccacaatctt ttaggaaaat tcgaatagac
    23761 tctttacaag tttccatatg ttccatttct tttagacaaa catggacaat ggcatttttt
    23821 tccaaagcat ccatagtcca gagattaagc tgattaaggc tgaccacatt gtccaatcgc
    23881 tccaggccac tctttacttg cttgatatca agaccttctg gcacagcatc caagaaaatc
    23941 ttgagtgtag accaaaaacg tggaagggct tttgaaagaa taaagaaaga aatgacaagg
    24001 gacaaaagag gatctaggat ataccagtcc gtaaatcgaa gaacaatcgc catcaggata
    24061 acagctaccc accctagcgt atcttccaga aaatgcagac tcagaataga ctcattcttt
    24121 gtctttccct taccaaccac cagactcgct aacagattga tagtaatcgc aataattcct
    24181 aaccagagaa tcccctcatc attgactggt tgcggatgca aaatcttcgt gacattttcc
    24241 aaaatgacta gaacagagcc cgttacgaga atcacagctg ttaccaaggc tcctagcagg
    24301 ctaaaccgct tatagcccaa ggtgtactga ttgtcttctt cacgattgga gattgtttct
    24361 aaaaaagctg atattccaat tgcaatcgca tctcccaagt catgcacaga gtcagcaaga
    24421 acagcgctag aaccaaatat tccacctgca ataaactcaa caatggcata agtcaaattt
    24481 aagaaaaaag ccacccaaac agcatatttt gccttcatat ttctcattcc tttgttataa
    24541 tagatttatg aacaccttgt tcattatcat tatccactaa aactcaaaga aaggatagaa
    24601 gcaaaacgtc agctttattc agttctgaac aatttgcctt aagtgtccat atgactaaca
    24661 ttgaccgccg tatcagcaaa accaaaaaag ccatctatca agcttttata caacttttga
    24721 atgctaaggg ctacgaggcc actactgttc aggatatcat tgatctcgca gatgtgggaa
    24781 gatccacctt ttactgtcac tatgaaagta aggagcttct tctggaccag ctctgccgct
    24841 acctcttcca tcatcttttt gaaagagagc aagccatttc aaccgaggac tacctcgccc
    24901 acctctttct ccattttcat aaaaaccaag accatatcac cagtctgcta ttttccaaaa
    24961 atgactactt cctccgtcaa ctccataaag agctagaaca ccatgtctat tccgtgctag
    25021 ctgataattt aaaagaagcc caccctaata tgcctacttc ttacctccaa cacttggtcg
    25081 tgtccaactt tatcgagaca ttgacctggt ggctcaaaaa aggtcaagat ttcacaggcc
    25141 aggaagttgt ccaattttat ctagaccttc tcattcctaa aaattgaata tagagtaaag
    25201 ctcagttgtc ttatttctag gttactgagt tttttatctt ttcaacaaca aaagaggacc
    25261 cgccgatcct ctttttcata ctataaatcc ttgattatca actatatctg ttttaatcga
    25321 aatctcaaaa cagcactttc aaacatcttt tcctagttaa gtaaatcagt attctgctta
    25381 gctgccttgc tccattgata ccaaccaact agactgttaa tgagataaat tagatatttc
    25441 ccttgaattt gcaggctttc tccccaccag agatagattg aaaaaacatt ggtagccgcc
    25501 cagaatatcc actgttcacg gtaaacagct gtcatgagga tttgccctac cccattggtt
    25561 gcatctgtga ttgaatcacg atagggacga ttggcaccaa tagactgata aatgaagcca
    25621 aaggccaacc accaaagcac actaatggaa agatactttg tccagccctt gccgtccagt
    25681 ttacgcgcga caaactcctg cttttccttc ttaaactgtg cctgataaat ccaaactaga
    25741 agtccaattg gctgcatgac tgtgaagtaa agtgtcgtca gcacctcacc ataaaagcct
    25801 ttctgtaggg ccaaaataag gtaaataaca gagttaatca agccaaaaag ataattactt
    25861 gctcgacctt ccgatacaaa gattacacag ataatccctg tcaagctaca aatcatccca
    25921 atccagtcaa caatacgatg ttcgtaaacc aactccagcc agagaggaaa acttcctaaa
    25981 accagcaaat aaatccactg ggcaaaacta cgatgggcaa agaggtcatc ccagatagcc
    26041 ttcatagttt ctgaaaatcc taaatcagcc atagccgcaa ccatacgacg gtaaccacct
    26101 gacatttcac ctagggttgt tttgatattt tcaattttct tttgcaaata agtatgcatc
    26161 atttctcctt ttgtttttaa agagccgtgt ctggatagac tttcggacgc aacgctctat
    26221 tagataatga actgcctata cacaagattt ctaaccttag tcgacatgag ctgaaacctc
    26281 ttatttgtta agtagttcac aaaatattat acacctattt tatgaatagt caactgtctt
    26341 tacagtaaaa ttttagaaaa tcatgaaaat tttctctttc tttccatttt aagtgacatt
    26401 cagtcattct cacatcaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26461 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26521 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26581 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26641 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26701 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26761 agtcgaatag gcatccgtga tttgaatatc ccctgactga attgcctgat aacgaagagc
    26821 tggctgcata gtcgccacat tgagattgag accatacatt gattgcaagc ccttatttcc
    26881 atcttcacgg tcgttaaact caagcgtaaa gcctgccttc agctgccctt ccactttttt
    26941 caaatccgaa atggtcttca agccatattc ttgcgcaatc tttttcggaa cagctacagc
    27001 ataggtattt tgataagaca taggtttgag ataggctaga tgatcctgct tggcaatgcc
    27061 atcacgcgcc acttgataaa cctgctctgg ctcatgactc accttgggtg atggttgaag
    27121 caaactttca gtcaccgtac cggtaaattc aggataaatg tcaatatcac cttttttcag
    27181 agcttcataa aggaaacttg tcgtcccaaa attcggttta acagtcgcag tcatgctggt
    27241 attttcttca atcagcaatt tatacatatt agccaaaatt tctggttctg ggcctatttt
    27301 cccagcaata atcacgtttt ccttctcttt ttgagccaaa agggctggac tataagacag
    27361 acccagtaat aaagccacca aggcaaaacc agagaaaatc gtccgcaatt tcgctttttc
    27421 cattactttt agtaggaagt taaaggcaat agctagcact gcagaagaaa gggccccaat
    27481 caaaatcaaa ctggcattat tacggtcaat tcccaacagg ataaaggaac ccagtccccc
    27541 tgccccaatc aaggtcgcca aggtagccgt accgataatc aagaccgctg ccgtccgaat
    27601 tccagacatg ataacaggca tggcaagtgg aatttcaaac ttcttgagac gctcccatct
    27661 ggtcatccca aaggcaatcc cagcctcttg aagactcgga tcaattccct tcagcccagt
    27721 aatagtattt tgtaaaatcg gaaaaatcgc ataaatcact agagctgtca atgccggtaa
    27781 agtcccaatt cccatcaagg gaataaagag tcccaacaag gccagagacg ggatggtctg
    27841 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    27901 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagtgaca actgcaaatg
    27961 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28021 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28081 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28141 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28201 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28261 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28321 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28381 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28441 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28501 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28561 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28621 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28681 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28741 tcattctttg tcctcaattt aaaacttccc tcgattagtc aagtcttcta ccttaggcat
    28801 gacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28861 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    28921 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    28981 agcagcactt ccttgtccaa tctcatgatt atgctgaatc aaatcgtctg ccacataatc
    29041 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29101 tttattttct gctttcttat ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29161 ttggtcattt tcaggtgttc gatagtagtc aatgacatcc caatgctcaa caatacgacc
    29221 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29281 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29341 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29401 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29461 aactcgtccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29521 catattctaa acctcatttc ccttctcttt caaattcgcc aaaattcttt cttgaaaacc
    29581 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29641 actgacacga tgccccactt ctttctggga cttgcctaac tccgttaaaa ctaaatactt
    29701 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29761 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29821 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    29881 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    29941 atgatgggct agcaaatgac catctttcat aacacctcca atttatttcg atatcgaaat
    30001 gaataaaaca attgtaacac tcatcgttct aactgtcaac tatttcgatt tagaaataat
    30061 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30121 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30181 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30241 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30301 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat ttcgaaactg
    30361 gaataggaca ccatgactgc taaaagattt ctataaattc atttaatttc ctcaatcaat
    30421 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30481 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30541 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30601 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30661 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30721 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30781 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30841 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    30901 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    30961 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31021 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31081 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31141 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31201 ttcagccgtt gtcaaaagga aatccttcat ccctgggaga agcaagtgac ctggatcata
    31261 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31321 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31381 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31441 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31501 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31561 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31621 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31681 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31741 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31801 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31861 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    31921 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    31981 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32041 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32101 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32161 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32221 acaatacacc atcaaagttg tttggatttt tcatgaaatt tacagaaaat agttgacttc
    32281 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32341 aaaacatttc taggaattaa tttgcctttc ctaatagagt tgttcatatc ttatttcaat
    32401 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32461 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32521 gcatgtcctc gataatctct ccacaggaaa tcgagcgact gtggataatc gtgctagctt
    32581 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32641 tgatgctgtc ctccattatg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32701 taaatacttc actgccaacg ttgctggtag gaaccaagtt ctcaaagtct tatctgaagt
    32761 tggcactcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32821 caagccggcg actgaagata ccctgatcga ccctgtcaac ccttatacag agacaaaact
    32881 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    32941 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33001 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33061 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33121 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33181 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33241 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33301 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33361 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33421 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33481 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33541 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33601 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33661 gaccagcaga cctggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33721 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33781 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33841 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    33901 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    33961 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34021 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34081 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34141 aaattatccc aaaccttcac catcatgaat ctagggaaag aaaccagcga gagtttgggg
    34201 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34261 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34321 aagtgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34381 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34441 agtctcttgc taggaatcat cggtagtctc gtctttatcc tacttctctg gagaggggga
    34501 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34561 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34621 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34681 cattagtttt caaaccttga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34741 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34801 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34861 cgccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    34921 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    34981 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atcttaacac
    35041 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35101 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35161 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35221 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35281 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35341 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35401 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga gggctcgtca
    35461 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35521 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35581 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35641 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35701 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35761 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35821 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    35881 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    35941 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcaaattct tcgacgactg
    36001 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36061 tatgcagatg aaattgtcgc cttcaaggac ggtcaggtct ttagcaaggg aagcaccgat
    36121 caaatcatgc aggctgacct gctcagccaa ctttatgaga ttcccatcac gctagctgat
    36181 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36241 ttcagtctct taatcaataa gatcaagaga ctccctaaat cgttatcaca ttttaaaaag
    36301 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36361 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36421 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36481 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36541 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36601 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36661 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36721 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36781 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36841 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaagg
    36901 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    36961 ctttcttgta ccaaaccttg aaattcaaac caactgatac aacatttgaa gactcacgcc
    37021 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgacatc ctctttgtca
    37081 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37141 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37201 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37261 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37321 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37381 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37441 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37501 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37561 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37621 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37681 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37741 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37801 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37861 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    37921 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    37981 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38041 cttattggcc acacctttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38101 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38161 gtccaaacga cccacagggt aaatacgttc tttgacattg ggcaagaggt cgacaaccgt
    38221 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38281 gtaaaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38341 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38401 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38461 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38521 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38581 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38641 aagcctgcaa ctttgccaag gctccactcg agttaacccc acggatggca tcaatttcta
    38701 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38761 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgaggcttgg
    38821 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    38881 catacttctg ggctaatttt cctaaacttt gctggatgcc tgtcggtggc agagagagga
    38941 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39001 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39061 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39121 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39181 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gattctttca
    39241 caataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39301 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39361 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39421 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39481 attcttcgat ttgagagagg aggtcctgct ccagatcatc ccccaagtct gtcacttctg
    39541 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39601 actcacccgt cacttccaga cgcatggcct gcagggttga gacataggct agatactgtt
    39661 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39721 agagcaagtc caggggtcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39781 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39841 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    39901 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    39961 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40021 gggaatggtg acaatcctcc gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40081 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40141 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40201 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40261 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40321 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40381 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40441 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40501 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40561 atggacttgc gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40621 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40681 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40741 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40801 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40861 gcattgtgag tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    40921 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    40981 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41041 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gagcctggat
    41101 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41161 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41221 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41281 ctgggtagcc ggcgtagaag tccatgttcc ctttaacaac gcggatgccc tcccaaagtg
    41341 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41401 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41461 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41521 agattgacta tttttttctt ccagggttaa ttcagctgat gactcacctg tctctcctac
    41581 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41641 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41701 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41761 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41821 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    41881 taattgagaa atggtttctg ccttaaggcg ggcattttcc tcaaaggtca tacctgtttc
    41941 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42001 aaagatagct cggaattcct tggttttacc ttcgttacga gtcgcaatca acaaggtttc
    42061 tctgactttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42121 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42181 gtttcgtccc atttcttgat taagcatatc taccacaaag gagaacaaac ggtaggtaga
    42241 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42301 ggagaattca aacagaggaa aatctgtctg atagtcgctc aaactgttaa cgccaccaaa
    42361 aatactataa gacccaacat accagtcctg gtcatcctta tattcataaa ttttatttgt
    42421 cataattcta catgctccac atgaatctct ttttccagcc attcttcacc aatttgtgca
    42481 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42541 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42601 tcgatgagct gaacctttgg ccccatcaca ttttggataa tagggcgaag gagtggataa
    42661 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42721 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42781 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42841 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    42901 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    42961 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43021 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagcagga
    43081 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43141 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43201 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43261 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43321 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43381 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43441 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43501 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43561 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43621 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43681 tgtttctttt tgaatccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43741 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43801 cttgctaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccacaggttg
    43861 ctcaaagcac cgctttgagg ttgcagataa aactgacacg gtttgaagag attttcgaag
    43921 agtattaatt tacataaata gccagtgttt gatagggttt gagtagaatt ttctcagaca
    43981 cttctgcatc ttcatagttt gatatcaaaa tctgtccatt ttggtagact gctggcaagt
    44041 cgatttccac ttctttagca taaaagttat tgagcactag taacttttga tcctcaaact
    44101 ggcgttcaaa agcgtagact tgtttgctat cttcaaaggc tggtttgtaa cttccttctg
    44161 aaatgattgg catttcctta cgcagtcgaa tcaagtcttg atagaaggtg aaaatcggac
    44221 cctggatttc attttctaca ttgatgtatt tataggattt accagctttc aaccatggag
    44281 tgcctgttga aaatcctgca ttttccgaag catcccactg catgggaatg cgtgaattat
    44341 cacgcgactt agcttgaata atctggaagg cttcttgctg actctttcct tcttctaaga
    44401 gcgtctgata ggcattaagc gattcgacat ccacataatc agccatagaa tcatagtctg
    44461 ggtcaatcat cccgatttct tcacccatat agatataagg tgtcccacgt gacaggtgaa
    44521 tgctagccgc tagcatggtg gctccttcct tgcggaagtt ttgaatatcg acaaaacggt
    44581 tcaaggcacg tggttgatcg tgattgttcc aaaagagggc actccaaccg tctttatcac
    44641 tcatttcctt accccaacta tggtaaagac tcttcaactc ttcaaaatca aagggagcca
    44701 aggtccactt ttgtccatcc ttatagtcca ccttgaggtg atgaaaatta aaggtcatgg
    44761 ataattcctg acgatcaggc gacgaataga ggacacagtt ttccatggtg gtagaagaca
    44821 tttccccaac tgtcataaag ctatcgtcag atccaaaagt ggcttggttc atcatacgca
    44881 aatagttatg aacgatgggt ttgtctgtat aagctggctt cccttcattt tcaggacagt
    44941 ccactgaaac ctcgtcctta ccaatcaaat tgatcacatc aaatcggaaa cctttgatac
    45001 ccttgtcgcg ccagaaatta acaaccttga aaagctcctt acggacattg gaattgcgcc
    45061 agttaaggtc agcctgggtc tcatcaaata ggtgaagata gtatttccca gtatccccga
    45121 aaggcgtcca tgcagaacca ccaaacttag actgccaatc tgttggttgg tcttggatga
    45181 agaaaaagtc ttgataatac ttatcaccag ctagggcttt ctgaaaccat tcatgctctg
    45241 tcgaacaatg attaagtacc atgtccagca taaagtcaat cttgtgctct ttaccgacac
    45301 acaccatttc ctcaaaatca gccatatcac caaaaagagg atccactgcc atataatctg
    45361 aaatatcgta accattatcc cgttgagggc ttggatagaa tggattgagc cagaccatat
    45421 ccacacctag tttggctaaa tagggaattt tttcgataat cccacggaaa tccccaatac
    45481 cgttttcagt ggtgtctttg taagattttg gatagatttg atagactact tttcctttat
    45541 caagtgtcat ctgtttctcc ttttctgata aaagggagga agcagtcttc cgtccctatt
    45601 tgtgctattt caattatact caatgaaaat caaagaacaa actaggaagc tagccacagg
    45661 ttgctcaaaa cactattttg aggttgcaga tagagctgac gtggtttgaa gagattttcg
    45721 aagagtatta gattcgtgta gcgaccatga gagatgctcc agcttggatc gttgtcggat
    45781 aagttccagt aatagtcgct gtataagcat cttggttggt gatgataaca ggagtttctg
    45841 tcaccagacc tgcagcctta atgacatcca tatcaaaacg aatcagttgc tggccaacta
    45901 taacgtgatc tccttggact acaagacttt caaaaccttt gccatcaaga cctactgtat
    45961 ccataccgat gtggatgagc aattcaactc cctcgtcaga gacaatgccg atggcatgct
    46021 tggtagggaa aagaaccgtc actgttccat taactggaga ggtcaactca ccttggcttg
    46081 gttcaatgac cagaccttgc cccatgacac ctgatgcaaa aacaggatcc gtcgcttgac
    46141 tcaattcttt cacttggcca gttagtgggc tgataatttc taccgaagta agttctactg
    46201 gttcatggct cacaaattct gcttcttctt gagcaacgaa ttctgcctgc aagttcgtat
    46261 cgccctctgt ttttgtaaaa agaccagcct tgcggaagaa gaaagtcaag agcattggaa
    46321 caacaatcgc aactagcata gttcctgcaa atggcagcat gtattgaggt tgaatagaga
    46381 gaatacctgg caaaccaccg ataccaatag aagccgcagt tacattaaaa gtaacggata
    46441 acatgcctgc aagggctgaa ccagtcatcc cagcaacaaa tggataaata tattttacat
    46501 taaccccaaa aagagctggt tctgtaacac cgagataggc tgaaatggtt gcaggaagtg
    46561 aaacctgagc ctcacgctca tcatggcgat gcatgaaata ataggcaaac acggctgagc
    46621 cttgagcaat attagaaaga gcaatcattg gccatagggc agtgccacca gcatccgcaa
    46681 tcaattgtgt atcaatggca ttggtcatat ggtgcagacc tgtgatgaca aatggagcgt
    46741 agagggcacc aaaaattgca ccgaagagcc atttaactgg accagttaaa cctgccaaga
    46801 caactgatga aagtccttgt ccaattgtcc aaccgattgg tcccaaaaca gtatgagcca
    46861 aaatcaaggc tggaatcaat gacaagaaag gtacaaaaat catagaaatg acttctggga
    46921 tatgcttgcg ccagaagatt tcaagataag acagactcaa acctgcaagc aaggctggga
    46981 taacttgggc ttggtaaccg atacgattaa cagtaaaata gccaaaattc caaacccagt
    47041 ttgccgcgat atcagctgtt ggcgttgaag caaccgcata ggcattgagc aactgaggcg
    47101 ataccaaaca gattccgaga acaattccca aaatttggct ggttcccatc ttacgagaaa
    47161 cagaccaagt aatccctact ggtaagaact ggaagatagc ttcaccaggc aaccagagga
    47221 agtgattgac acctgcccaa aactgagagg attctgtgat ggtcttgcca tccaacatcg
    47281 accaatggac accttccaag acattacgga aaccgaggat caatcctccg actatcaagg
    47341 ctggaataat cggagtaaaa atctccgcca gagtggtcat aacaccttgg accacgtttt
    47401 gattactctt agctgcagac ttggctgctt ctttggaaac accctcaata cctgaaacgg
    47461 ctgtaaaatc attataaaag atgggcacgt catttccaat gattacctga aattgacctg
    47521 catttgtaaa agttccttta acagctggaa ttgactcgat agctttaaca ttagccttct
    47581 tatcatctcc taaaacaaag cgcatccgtg tcgcacagtg agttacggca atcacatttt
    47641 ctttgcctcc aattgcctga agcagatctt tggcttcttg ttcaaatttt cccatttgat
    47701 tctccttata cttgtcaaag caagtttgat ttgataagta tattgtaaac gataccaaac
    47761 ttgtctgcaa cttgtttggt ataaaaaggg tgtttttttg taaattttct agcacttgta
    47821 tggtaaaata gatacaggtg ttcattaaac taaactaaaa acctatttaa gcaggcaaaa
    47881 tgaagaaata ccaacaatta tttaagcaaa tccaagaaac cattcaaaac gagacttacg
    47941 ctgtcggaga tttccttcct agcgagcacg accttatgga gcaatatcaa gtgagtcgtg
    48001 ataccgtccg aaaggccctg tctctcctcc aagaggaagg attgatcaaa aagataagag
    48061 ggcaaggttc tcaagtcgtc aaagaagaaa ccgtcaattt ccctgtatcc aacctaacca
    48121 gctaccaaga actagttaaa gaacttggac tgcgctctaa aaccaacgtg gtcagtctgg
    48181 acaagattat tattgataaa aaatcctcac tgataaccgg tttcccagag tttcggatgg
    48241 tttggaaggt ggtccgccag cgtgtggtgg atgatctggt atccgttctg gatacggact
    48301 atctggatat ggaactcatc ccaaatctca ctcgccaaat tgctgagcag tctatctatt
    48361 cttatataga aaatggcctc aaactcctta ttgattatgc tcagaaggaa atcaccattg
    48421 accactcaag cgaccgagac aagattctca tggacattgg caaagaccct tatgtcgttt
    48481 cgattaaatc aaaagtctat ctccaagacg gacgccaatt tcagtttacc gaaagtcgcc
    48541 ataagttaga aaaatttaga tttgtagatt ttgcaaaacg caagaaataa aagactgaga
    48601 caccagatct cagccttttt cggctctata atatttgtag tgggtaaccc ccctatggat
    48661 attatgg
//
LOCUS       DAVLHB010000011        43366 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLHB010000011 DAVLHB010000000
VERSION     DAVLHB010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.011"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(286..827)
                     /locus_tag="VXE36_000711"
                     /pseudo
     CDS             complement(286..827)
                     /locus_tag="VXE36_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(903..1214)
                     /locus_tag="VXE36_000712"
     CDS             complement(903..1214)
                     /locus_tag="VXE36_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0779063.1"
                     /translation="MGLPITRKEISNWHIKASQYYLESLYNLLREKLLEQALLHADET
                     SYRVLESDSQLTYYWTFLSGKAEKQGITLYHHDQRRSGSVVQEFLGNYSGYMHCDMLR
                     Q"
     gene            1334..1641
                     /locus_tag="VXE36_000713"
                     /pseudo
     CDS             1334..1641
                     /locus_tag="VXE36_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1796..2119)
                     /gene="tnpB"
                     /locus_tag="VXE36_000714"
     CDS             complement(1796..2119)
                     /gene="tnpB"
                     /locus_tag="VXE36_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0779064.1"
                     /translation="MTIHLSSLGQVYLVCGKTGMRQGIDSLAYLVKTHFELNSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(2100..2285)
                     /locus_tag="VXE36_000715"
     CDS             complement(2100..2285)
                     /locus_tag="VXE36_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779065.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2589..4151)
                     /gene="guaA"
                     /locus_tag="VXE36_000716"
     CDS             complement(2589..4151)
                     /gene="guaA"
                     /locus_tag="VXE36_000716"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0779066.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4293..4991
                     /locus_tag="VXE36_000717"
     CDS             4293..4991
                     /locus_tag="VXE36_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0779067.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5034..5930)
                     /locus_tag="VXE36_000718"
     CDS             complement(5034..5930)
                     /locus_tag="VXE36_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0779068.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLSYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5939..6874)
                     /locus_tag="VXE36_000719"
     CDS             complement(5939..6874)
                     /locus_tag="VXE36_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0779069.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6871..7596)
                     /locus_tag="VXE36_000720"
     CDS             complement(6871..7596)
                     /locus_tag="VXE36_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0779070.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7680..8315)
                     /locus_tag="VXE36_000721"
     CDS             complement(7680..8315)
                     /locus_tag="VXE36_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0779071.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYEALSKALKDYLY"
     gene            complement(8317..9144)
                     /locus_tag="VXE36_000722"
     CDS             complement(8317..9144)
                     /locus_tag="VXE36_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0779072.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9166..9501)
                     /locus_tag="VXE36_000723"
     CDS             complement(9166..9501)
                     /locus_tag="VXE36_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV0779073.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9502..10218)
                     /locus_tag="VXE36_000724"
     CDS             complement(9502..10218)
                     /locus_tag="VXE36_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV0779074.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYDFNGIEQYISQEDYNRYLSD
                     LNEDKMKVEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            10731..11342
                     /locus_tag="VXE36_000725"
     CDS             10731..11342
                     /locus_tag="VXE36_000725"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0779075.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11387..12115
                     /gene="rlmB"
                     /locus_tag="VXE36_000726"
     CDS             11387..12115
                     /gene="rlmB"
                     /locus_tag="VXE36_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0779076.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKNEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12154..13065)
                     /gene="trxB"
                     /locus_tag="VXE36_000727"
     CDS             complement(12154..13065)
                     /gene="trxB"
                     /locus_tag="VXE36_000727"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0779077.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLGDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13131..13355)
                     /locus_tag="VXE36_000728"
     CDS             complement(13131..13355)
                     /locus_tag="VXE36_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0779078.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13433..14176)
                     /locus_tag="VXE36_000729"
     CDS             complement(13433..14176)
                     /locus_tag="VXE36_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0779079.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14176..14976)
                     /locus_tag="VXE36_000730"
     CDS             complement(14176..14976)
                     /locus_tag="VXE36_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0779080.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLIYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15134..15490)
                     /locus_tag="VXE36_000731"
     CDS             complement(15134..15490)
                     /locus_tag="VXE36_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0779081.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15484..16014)
                     /locus_tag="VXE36_000732"
     CDS             complement(15484..16014)
                     /locus_tag="VXE36_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0779082.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(16014..16508)
                     /locus_tag="VXE36_000733"
     CDS             complement(16014..16508)
                     /locus_tag="VXE36_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779083.1"
                     /translation="MEIRLAFLNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSSEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16643..17089
                     /locus_tag="VXE36_000734"
     CDS             16643..17089
                     /locus_tag="VXE36_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0779084.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17086..17733
                     /locus_tag="VXE36_000735"
     CDS             17086..17733
                     /locus_tag="VXE36_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0779085.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17754..18335)
                     /gene="pdxT"
                     /locus_tag="VXE36_000736"
     CDS             complement(17754..18335)
                     /gene="pdxT"
                     /locus_tag="VXE36_000736"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0779086.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18336..19211)
                     /gene="pdxS"
                     /locus_tag="VXE36_000737"
     CDS             complement(18336..19211)
                     /gene="pdxS"
                     /locus_tag="VXE36_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0779087.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19363..20742)
                     /locus_tag="VXE36_000738"
     CDS             complement(19363..20742)
                     /locus_tag="VXE36_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0779088.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21037..21960
                     /locus_tag="VXE36_000739"
     CDS             21037..21960
                     /locus_tag="VXE36_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0779089.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIKLDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            22020..22625
                     /locus_tag="VXE36_000740"
     CDS             22020..22625
                     /locus_tag="VXE36_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0779090.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22644..23888
                     /locus_tag="VXE36_000741"
     CDS             22644..23888
                     /locus_tag="VXE36_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0779091.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGDHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24111..24368)
                     /locus_tag="VXE36_000742"
     CDS             complement(24111..24368)
                     /locus_tag="VXE36_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0779092.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24410..26446)
                     /locus_tag="VXE36_000743"
     CDS             complement(24410..26446)
                     /locus_tag="VXE36_000743"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0779093.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFRGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26658..27575)
                     /gene="glyQ"
                     /locus_tag="VXE36_000744"
     CDS             complement(26658..27575)
                     /gene="glyQ"
                     /locus_tag="VXE36_000744"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0779094.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQDCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27946..28706)
                     /locus_tag="VXE36_000745"
                     /pseudo
     CDS             complement(27946..28706)
                     /locus_tag="VXE36_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            complement(28979..29821)
                     /locus_tag="VXE36_000746"
     CDS             complement(28979..29821)
                     /locus_tag="VXE36_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0779095.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29935..31326)
                     /locus_tag="VXE36_000747"
     CDS             complement(29935..31326)
                     /locus_tag="VXE36_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0779096.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31561..31938)
                     /locus_tag="VXE36_000748"
                     /pseudo
     CDS             complement(31561..31938)
                     /locus_tag="VXE36_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            32153..33130
                     /locus_tag="VXE36_000749"
     CDS             32153..33130
                     /locus_tag="VXE36_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0779097.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVSQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            33127..34209
                     /locus_tag="VXE36_000750"
     CDS             33127..34209
                     /locus_tag="VXE36_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0779098.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSKT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLIYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34273..34827)
                     /locus_tag="VXE36_000751"
                     /pseudo
     CDS             complement(34273..34827)
                     /locus_tag="VXE36_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(34861..36132)
                     /locus_tag="VXE36_000752"
                     /pseudo
     CDS             complement(34861..36132)
                     /locus_tag="VXE36_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(36189..36451)
                     /locus_tag="VXE36_000753"
                     /pseudo
     CDS             complement(36189..36451)
                     /locus_tag="VXE36_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            complement(36554..36691)
                     /locus_tag="VXE36_000754"
                     /pseudo
     CDS             complement(36554..36691)
                     /locus_tag="VXE36_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(37075..38271)
                     /gene="tuf"
                     /locus_tag="VXE36_000755"
     CDS             complement(37075..38271)
                     /gene="tuf"
                     /locus_tag="VXE36_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0779099.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(39193..40062)
                     /locus_tag="VXE36_000756"
     CDS             complement(39193..40062)
                     /locus_tag="VXE36_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0779100.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKATEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(40286..40894)
                     /locus_tag="VXE36_000757"
     CDS             complement(40286..40894)
                     /locus_tag="VXE36_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0779101.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(40852..41958)
                     /locus_tag="VXE36_000758"
     CDS             complement(40852..41958)
                     /locus_tag="VXE36_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0779102.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(42069..42323)
                     /locus_tag="VXE36_000759"
     CDS             complement(42069..42323)
                     /locus_tag="VXE36_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779103.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(42663..43109)
                     /locus_tag="VXE36_000760"
     CDS             complement(42663..43109)
                     /locus_tag="VXE36_000760"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0779104.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(43182..>43366)
                     /locus_tag="VXE36_000761"
     CDS             complement(43182..>43366)
                     /locus_tag="VXE36_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0779105.1"
                     /translation="ERKKRVVKNRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVW
                     AALKQIKVTLKKDDEL"
BASE COUNT        12716 a         9461 c         7826 g        13363 t
ORIGIN      
        1 atattgaaaa atctccagac tagagaactc acggatagtt cctaatctgg agatttctta
       61 tttgcacttt tcttgtacaa ctttagtcca cggtaaatag gcctctaaaa cctctttgtt
      121 tacgagagtt tcctcgtttg gaagacattc tagaagatag gatagatatt tctcgctatt
      181 tataatggat tgaaataaga tatgaacaaa tcgattagga aaggaaaatt gatttataga
      241 aatattttag cagtcgatgc gtactgttat agattcaacg cactataatt gatgacgttt
      301 agctgtttcc aacaaactca taataatagc tcttgcttta gctccttcaa aactttgaga
      361 aaataaccac cctcgctttt ttaaactgag ctcaggctaa aagagtccac tggactcttt
      421 tactccgtcc cataaccaat gatttaatgg cgcgttcagc tagattattg gaaaggacca
      481 gatgtccgtc ttttaaaatg gtcttaaagg tttctttata cttgaggctg tattcaattg
      541 cccttcctag ttttgaacct gctaaaactg actgacggcg gcaccaagca aagaagtctt
      601 ccattagggg ctggacgttt ctgtagtcgt tcatcagctg gcaaagcctc ccagtctctt
      661 tccaaggcaa ataactggtc acgataggct aaacctttag ctcctaagga tgatttatct
      721 gcttgcttgg gggtcgcttc aaaaaatttc cttctcacat gcgcccaaca tccaacaagt
      781 tcagcttctt ccagttgacg ataagcttct agcggttcgc agtttaccaa gcttagcgtc
      841 gccttgctcc taaaccttag actgctatcg cataggcaga actagaggac taaagttcta
      901 agttactgcc gcaacatatc acaatgcata tagccagaat aatttcctag gaattcttgc
      961 actaccgaac cactccgacg ctgatcatgg tggtacagcg taatcccttg tttctcagct
     1021 ttcccagaca aaaaagtcca atagtaagtc agctgactat cactttctaa gacccgataa
     1081 gaggtttcat ctgcatgaag aagagcttgt tctaacaact tttctcgtaa aaggttataa
     1141 agggactcta aatagtattg actcgccttg atatgccaat tagaaatttc cttacgtgtg
     1201 attggtaaac ccatcttagc ccaatcttct tcttagcgat aattaggtac cttcagatta
     1261 aacttctgat ggatggtgtg agcgataata gaagctgagc caaggctatg cgccaaaggg
     1321 gctttaggaa taggagcttt cacaagctta tccagatgat tatcttttac tcgttatgaa
     1381 caatgctata tggcataaat caagtacctt aaagattccg actaatattg gctttgcatt
     1441 tattcctcca tacacaccag agatgaaccc attgaacaag tgtggaaaga gattcgtaaa
     1501 cgtggattta agaataaagc ctttcaaact ttggaagatg tcatgaatca acttcaagat
     1561 gttatacaag gactggagaa ggaggtgata aagtccatcg ttaatcggag atggactaga
     1621 atgctttttg aaagcagatg agtataaaaa gaaagtcctc atttcaatag aaatcacgac
     1681 tttctgatgg atttatagta aaatgaaata ataacaggac aaatcgatca ggacagtcaa
     1741 atcgatttct aacaatgttt tagaagcaaa ggtgtactat tctagtttca atctactata
     1801 tttttggagt gatagaaaag cctttcatca gccaatctac ttgttcaggt gcgagagctt
     1861 tgacatcctt ttctgtactg ggccaagtca gtctgccgtt ctcaaagcgt ttatataata
     1921 gccaaaatcc ttgaccatcc cagtaaagaa ctttaaagcg gtctttacgt ccaccacaaa
     1981 agagaaaaac ttgacctgag aaagaattca attcaaagtg ggttttaacc agataagcca
     2041 gtgaatcgat tccttgtctc atacccgttt tcccacatac gagatagacc tgccctaggc
     2101 tagatagatg aattgtcata gagcaacacc ttatccaaaa gctgttctat catttcgaga
     2161 ttgagagatt gaaaaaaact tacttcaagc ttgccaatac gaattttaag cagaatatca
     2221 tttctctttt tagaatcaaa acgacgagat tgtggaatct ctacaggaac aataggttgt
     2281 ggcattaaaa tatcctccaa tagttttact ttactaatag tatacaggag gagctccatg
     2341 aatgatagat accttgttat gacgcgctta ccatattaga aagttggctc tctaattaaa
     2401 ttaattctca ttatatatat caaaagaccg cagcttgaaa actacggtct aattttttgt
     2461 ccaaatgtaa accacttgga actattattc aatttattct ttttagcaaa tgttcccgtt
     2521 ttaatcccag ttacagtttt taatcctctg taaccgttga ttttacaaag cttttaattt
     2581 ttttgcgatt actcccactc aactgttgca ggtggtttac ttgtaatatc gtagacgata
     2641 cggttaacat gatccacttc atttacgata cgtactgaga ttttttgaag tacttcccat
     2701 ggaattttgg caaaatcagc agtcatacca tcgatagaag tgatagcacg gattgcaatc
     2761 gtgtagtcat acgtacgacc gtcacccata acaccgactg aacgaacgcc tgtgttaaca
     2821 gtgaagtatt gccaaatatc gcggtcaagt ccagctttag cgatttcttc acgaagaata
     2881 gcgtctgatt cacgaacggt ttcaagtttc tcttcagtga tttcacccat gacacggata
     2941 gcaagtcctg gtcctgggaa tggttggcgc catacgatat ggtctggcat accaagctct
     3001 gtaccaagag cacgaacttc atccttgtaa agagtattaa gtggttcaat caattcaaac
     3061 tgcatatctt ctggaagacc acccacgttg tggtgtgact tgatagtttg agctgtatcc
     3121 gtaccagact cgataacatc tgtgtataaa gtaccttgag caaggaattt cacatctttg
     3181 agcttgcttg cttcgtcatc gaatacatag acaaactcgt taccgatgat tttacgtttt
     3241 tgttcaggat cagaaacgcc agcaagtttg tcaaggaaac gtttagcagc gtctgctttg
     3301 acgatattca aaccaaactt accaccgagc atgtccataa cttgatcagc ttcgccttta
     3361 cgaagaagac cgtggtctac gaagatacag atcaattgat cgccaatcgc tttttggaga
     3421 agaaccccaa cgacagatga gtcaacacca cctgatagac caagaaggac acgtttatca
     3481 ccgacggttt cacgaatttt tttgatctgc atgtcaatga aattatccat tgaccagtca
     3541 cctttagcct tacaaatgtt aagggcaaag ttacgaagga tatcatttcc gtatacagaa
     3601 tgacgaactt ctgggtggaa ttggataccg taaatgtgtt tatctgggtt ttcgatggct
     3661 gcgtatgggc agtcagctga tgtacctgta cgaacaaagt cagcaggaat ctcagtaacc
     3721 gcatcaccat ggctcatcaa aacagtctgt tcatcaggtg ttgattcaaa aagcgctgat
     3781 ggtgtgtgag ttagggttga ttgaccgtat tcacgatttc cagcatcacc tgcaggaaca
     3841 acttttcctc caagtttatg ggtcaataac tgcataccat aacagattcc caaaattgga
     3901 attccgagtt cgaagatttc tgggtcaata tcaaatgaac catcttcata tacagaattt
     3961 ggaccacctg atagaataat tcctacagga ttgacttcac gaacttcagc agctgaaatt
     4021 ttatggcttt ttagttctga aaaaacacca atctcacgga tacggcgtga aatcagctgg
     4081 ttgtactggc taccatagtc caatacgatg attttttcta catcttgcaa atcagttgaa
     4141 atgttgctca tctttttcct ttctcaaaag aaatatcttt tctcaatatt ctatcacaaa
     4201 taagggcgaa ttaccaacta aacaaggcga agtttgactt tttctagttt attggggtac
     4261 aatagagaaa agatagaaat gaagtgaaaa atatgctacc tgcttatatg aaaatccatg
     4321 atcagataaa aaaggatatt gacgagcacc gttgggctat tggtgagagg cttcccagtg
     4381 aaagagattt agctgagcag tttgcggtca gtcgcatgac cctccgccaa gccgtatctc
     4441 tattagtcga agaaggcgtc ttagagcgcc gtgtaggaag cggcaccttt gtttccagta
     4501 ctcgagtaca agaaaagatg cgagggacaa ccagttttac tgaaattgtc aaatcccaag
     4561 gtaaagttcc ctctagccag ctcatttcct acaaaaaaac cattcccaat gagcaagaag
     4621 ttgccaagct aggaattttt ccaacggaca atattatccg aatggagcgg gtccgctatg
     4681 ccgaccaagt tcccctagtt tatgaagttg cttctattcc tgaaaaattc attaaggact
     4741 ttaaaaaaga agaaatcacc agtcatttct tccaaacctt gcagaaacat ggctatcgta
     4801 tcggcaaatc tcaacagacc atctatgctc gccttgctaa agaaaagatt gcccactatt
     4861 tggaagttga aaaaggacat gctattcttg gattgacaca ggtttcctac ctagaagatg
     4921 gtactgcttt tgaatacgta aaaagtcaat atgtaggcga acgctttgaa ttttatcttg
     4981 aaaataatta gattaccacg caaaaactct ctgtcacaga caaagagtct tttttatttt
     5041 tctaagaata aatctttcaa agaaatcaaa gttacagcaa acaatatcat tgccatacca
     5101 agaaaatcaa tgggataaaa ttgttcattc attattaaga aggcaaagaa aaccgccgat
     5161 attggctcaa ttgaagccaa caagcttgac ttgaccggtc ctatcagact ggctccttta
     5221 aggaaagctg tataggcaaa gacagtcccg ataaggataa tgcctgcaaa cgcaaggaga
     5281 aaatcaagac tagtcgggat attggcctgt agaacccctg taaaaggaag ggcgaccaaa
     5341 cctgctataa ccattcccac accaatgacc aagctactcc cccacttttt aatcaaggct
     5401 atgggtaaaa tgatatatag agcataagtc aaggcagaaa agagacccca gaacaggcca
     5461 gcaggtgtca tggataactg gtccaactgc ccatgtgttg cgatcaggaa ggttcctccg
     5521 atggcgaata tgatggaaac tatctctccc agtgtcggtg ccaccctatc cttgatacag
     5581 ctataaatta aaattccgac aggacaaaca tactgaagca ccgtcgctgt tcccgcattg
     5641 gtctcctgaa tagcagacag ataggcgaat tggttgagaa aaagaccaat cagagcaaaa
     5701 ataagaagag acagcaaact ctttctatcc tttaaaaaga ccagtatttt atcctttgca
     5761 gtagcataag acaagagcat gagaattcca ccagcgatta aaagacgcaa gttggtcaag
     5821 accagagccg aaattccgtg tgccattagg tattggccac tcgttcctga caacccccaa
     5881 gcaataccag ccacaactgt tagtaaagtc ccttttaaac tatttgacat gtctctcctt
     5941 actcttcttt gcgaatcaag ttcatcactt gattgcggtc taatatccat tgagctctct
     6001 cgtccttttc ataggtacga ttcgatagga aaatagtggc ttcttgcttc tgacgattcc
     6061 acatgataaa ggtacctgta tagcccgtat ggtctagcca atctccttcc aaattccatg
     6121 ctaaagaacg ttccttgtca tccaaaggag aaaaattttg atttaagtct cttgcaaaat
     6181 catctgctaa atagtgttct aaaaaggttt gtaaatcctt tatagtcgaa aataaaccag
     6241 cactcccagc atgtctaccc aggagacgag ccttgggatc atgcactatg cctgcctcta
     6301 cacctctaac tgttggaaca gcaagctcaa ctggcccaaa cttagtttcc gtcattcccc
     6361 aaggtttcca gacttgatcc tttaaaatca catccaaatc ttgattaaaa attctttcca
     6421 aaataaagcc caacagcaaa aaatggacat ccgaataaag aaaggctggc tgacttcgtc
     6481 tgttgagatg aaacatcgct tcctttaatt caggggctgt taaaagatca cgattaggaa
     6541 taaaaggatc aaggtctgtt gcatgagtca agagctggcg aatagtgatg tctggataat
     6601 cactctcagg taaaaaatct attaccagtc tatcaatatc taattgacct atttcccaca
     6661 agaaggtaca aactgtgcca accccaacaa ccttgctgac actagctagg tcataaacta
     6721 gtcctgcctc agtctgcaag ccatgctctg gggcactctg gcctaaatag aactctgtcc
     6781 attgattgtc cttaaaatac gcaaaagagg ctccgggata aattcctgcc tcgatttgtt
     6841 cttctatttt tttaataatc ttggtccact tcatacttct tcaaaccaca attcaacatt
     6901 atttctatct ttaccaagga agaatttttc agacttagga ataaaatatt cagtagactc
     6961 aaacttctgg cgaagacttg ctatgtctaa ttcattgacc aagaacttga gcatagataa
     7021 gtcccaggta accgtattgt ccacagtcaa atcctgcccc tgagctggaa taaaatcaag
     7081 ggatgcccca atttcagatg attccaagaa actttcgata tcagttggga gatgtaattc
     7141 catagaaatc tcaaatttac ttaaagaaat tgatgccaaa tctgtttgaa attcaggctt
     7201 ttctcctact tctactagac ttgctctgtc atcttccgca tgaatcaaaa tcaaatcatc
     7261 ttctggtgag aaaatttcaa aagcgtagcc attttgacct ttatataatc gatgaatcga
     7321 atctgtttta gataagattc cttcaatttc taagggattt tccaccttga caatcaatct
     7381 agctagtttt tttcttccct ctaccttacg agtacgcata ctgggagctt cttctaaaac
     7441 cagcttttca agacccgttt ggtcacctag tgacagaaag gccgattctt ctaacaaggc
     7501 cttcattcca agggtttcaa tataaaatgt ttcatttaat tttctattat tagcttttaa
     7561 agtaggaata atccgtacaa tctgatttac attcataaat tcctccgtca ctttttattt
     7621 taaaggattt tagaattttt tacaagatat tatgctcaaa tttaacatta tttagctatt
     7681 tagtaaagat agtctttcaa ggcttttgac aaagcctcat aaccagcaat actgaggtgc
     7741 agtccatcag ttgtatattc ttttttgagt tggcctgctt ggtctgtcaa acaatcaaat
     7801 actggcacaa attccacctg catataggca gatgcaagct cttgataggc ttgattccaa
     7861 ttctgaattt tttcattcga gcggatatag actgcctgct ggtacttctc tccctcattg
     7921 acaggcaaaa tggaaagcaa tttaatctct gtcaatggat aatcgcgagc aacggattga
     7981 atgatagctt cgagattatt gagagcctca ttcacaggaa catcctttcc gatatcattt
     8041 gtcccaatca gaagaaaaat tttatctact gctccaccat atagatgagc atcaaggttc
     8101 tctagtaaca gtcctgtctg atagccacga attcctcgat tgacaatcgt ctttgaagtc
     8161 ccaaatagct cctgtagagg ataatactcg acaatggaat ccccaataaa aagaatgttt
     8221 ggttctacaa cagaaatgtg atttagatga cgatatttgg tttgaatttt ttcttgttcc
     8281 tttaggagcc aattttctaa taactgtact gccacttcat tctccttttt ctaaccagtt
     8341 ttccaagact tgataaactc ctccttggct gttggctggt gctagagcag tcgccacagc
     8401 tttggctttc tcatcagcat tttccatcgc ataggcaatt ccagccattt caagcatttc
     8461 aacatcattt tcactatcac caaaagccat gatttcttgg gatttcaagt cccagcgctt
     8521 gagtaattcc tccaagcccc atgctttatg aatcccagct tggaggatat caatgcaacc
     8581 atagccactg gatacagctc ggacacggcc atcaaagaga gcattgattt cttccaaaac
     8641 cgaactcaaa cgttcctcac caacaaccat gctcatcttg agcacaccac caaagaggtc
     8701 agatgttaat tcatccacaa attgcatccg ttggtagaat ttttcaatca tttctggagt
     8761 cataaaactt tcaagatctg taaaaatcgt accttccttg acaaaatcac ccttcatccc
     8821 cgttacaaca aactggtcct gacacgctcg acccttgaaa tgagccaaag ccttgttgac
     8881 aatggcgtca tcccatgtct gagcctgaat caattcattg ttttcaaaaa tacgagcgcc
     8941 attagcaaca accagaacca ctcgatccac caagggactc agtagttgtc tcatgcggtg
     9001 aatttcattg cccgtcgcaa tgacaaaacg aatgcccctt tgatccaact gatctaaaat
     9061 cttttccaat cgtgggagat caagctgacc tctagcatcc agcaaggtcc catccatatc
     9121 tgtcgcaatt accttaatca tcatttactt tcctctggat tcaagctaat accacttcaa
     9181 tcccacatgt tcattcattt ctttataggc tgtatcaatt cgttccttag tcgcttcatc
     9241 taactggtca cgatgactgc catcctctat aaaatcttcc aaaatataag tttggtaatg
     9301 atacaaggga tatccttctg gtgaaaaggt tccctttggt gttcgattga cccaagtagg
     9361 atgagcttta gctgttccga tagttgtttt tccatccttc ttcttgatgg tgacatccat
     9421 gagaacacca cgttcagtcc acttagcatt ctcttcatct cccatagatt caatccgttg
     9481 attggaaatg aagttcccca tttaatagat aatgagtttc ttatctccat ctttttcaac
     9541 cgtttcagat ggttcaacaa cgtgaggatg ccctccaaag ataatatccg ctccccaatc
     9601 gatcatcttg tgataaagag ctttttgttc ttcagttggt tccaatcgat actcaacacc
     9661 catctgaagc atgataatgg tgatatctgc ttccttctct gcccgttcaa tttcaacctt
     9721 catcttatct tcgtttaaat ctgaaagata acgattatag tcttcctgag aaatatactg
     9781 ctcaattcca ttgaaatcat aggaataggc taacaatgca accttgatac cattcacttc
     9841 cttaatgacc agcggagcct gatcacgtgg ttcgtgcgta taaactccga ttggagtgat
     9901 tccagctttc tcaataatat cggccgttga aataactccc tcaatttgcg aatccaaaat
     9961 atgattatga gctaaatcca gcacatgata acctgcctcc ttaatagcat ccataacttc
    10021 agcaggagca ttaaagagaa gataacccgc taaataatga tccttattaa tggttccttc
    10081 gaaatcacca atagctaaat ctgcttgctt gagccaagga gtcacatact caaaattttc
    10141 atgaaagtca taggtaccgt cttctttttt agctgaaaag aaaagtccat cgtggtagag
    10201 caaatccccg tgggccataa ttctggcagt tttttcctct tcctactcct gagacttttg
    10261 cttagtcccc tcttgagaaa tagtatctcg tttttgacta gtcaagggat tccttggaag
    10321 ctttcaaaca acaagaccaa gcccattgat aaaccaactg ctagcaagag tatcgccaca
    10381 aatcccttat tgctccactt gcgataactc ctaaaaagtt taccaagccc ttcataaaac
    10441 gaaaagctaa accaccctga tttcgatttt gtcttctttg tatcttcgtt ctccctactt
    10501 tcttatgcaa gccttttctt tttattatat cacagataag tatttctttc acaattgaat
    10561 tgaacttcct atctattttc tataaatcct aaatgccata atgctttcaa ttcttgtcat
    10621 tttgtgatat catgtagagg aaatgaacta atccacagtg gcttattcca agtataccac
    10681 ttgggctttg gcagtagcta actgcactaa acataatata aggagagaaa atgtctgcaa
    10741 tagaacgtat tacaaaagct gctcacttaa ttgatatgaa cgatattatc cgtgaaggga
    10801 atcctactct acgcgcgatt gctgaggaag tcactttccc cctatctgac caggaaatca
    10861 tcctaggcga aaagatgatg caattcctta aacattccca agatcctgtc atggctgaaa
    10921 aaatgggact ccgcggtggt gttggactgg ctgctcccca gttagatatc tcaaaacgca
    10981 ttatcgctgt tttggtacct aatattgttg aagaaggcga aactccacag gaagcctacg
    11041 atttggaagc cattatgtac aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc
    11101 ttggcgaagg agaaggttgc ctgtctgttg accgtaacgt gcctggctat gttgttcgcc
    11161 atgcccgcgt tactgttgac tactttgaca aagatggaga aaaacaccgt atcaaactca
    11221 aaggctacaa ctccattgtt gttcagcatg aaattgacca cattaacggt atcatgtttt
    11281 acgatcgcat caatgaaaaa gacccatttg cagttaaaga tggtttactg attcttgaat
    11341 aaagaaaatc ccgttgcaag acggggtttt gtgttataat agaggcatga aaacaaatga
    11401 tattgtctat ggcgtccacg ccgttaccga agccctcctt gcaaatacag gaaacaaact
    11461 ctacctccaa gaagatctcc gaggtaagaa tgttgagaaa gtcaaggaac tagctacaga
    11521 aaagaaggtg tccatttctt ggacatcaaa aaaatctctc tctgagatta ctgaaggtgc
    11581 tgttcatcaa ggttttgttc tacgagtgtc tgaatttgcc tatagcgagc tagattacat
    11641 ccttgcaaaa acacgccaag aagaaaatcc acttctattg attctagatg gtctaaccga
    11701 tccccataat ctaggttcta tcttgcgaac agccgatgcg accaatgttt caggtgtcat
    11761 cattcccaag caccgtgctg tcggagtaac tcctgtcgtt gccaaaacag ccacaggtgc
    11821 tattgaacac gttccaattg cccgagtgac caacctcagt caaaccttag ataaacttaa
    11881 gaatgaaggt ttctggacct ttggaacgga tatgaacggt actccttgcc acaagtggaa
    11941 tacaaaaggg aaaatcgccc tcatcattgg aaatgaagga aaaggtatct ctagcaacat
    12001 aaaaaaacag gtcgatgaaa tgattaccat tccgatgaat ggacatgttc aaagccttaa
    12061 tgccagtgtt gctgcggcca ttctcatgta cgaagttttc cgaaatagac tataaaaaag
    12121 tttccagtca tctgattgga aactttttta tgattaacta tgttctgtaa tgaatttata
    12181 ggcttcttga ccagcgatag ctccatctcc aaccgctgtt gttacttggc gaaggtcttt
    12241 caagcgaaca tctccaactg caaagatacc gtcgactgca gttttcatgt ggttatctgt
    12301 cacaatccat cctgcctgat cttggatatt caattcttta acaaaatcgc caagagggtc
    12361 caatccaaca tagataaaga caccaccgaa gacttgttct gtcacttgac ctgttttcac
    12421 attttcaaat acgactgatt ctactcggtt ttcacccttg atttccctta ctacagaatc
    12481 ccagataaag ctgatttttt cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg
    12541 aagttggtca cgacggtgaa caatggtaac agtcttagca aaacgagtca agaagagggc
    12601 ttcttcaaca gctgaatctc caccaccaac taccaataaa tcttggtcac ggaagaaagc
    12661 accatcacac acagcacagt aagaaacacc acgactgttc agttcttctt ctccaggtac
    12721 tcccaaagga cggtgtttag aaccagttgc tacgataact gtacgtgttt catatgtttg
    12781 gtcatcagtc atcactttct taaaatcacc atggtcttcg acattttcaa cataaccata
    12841 aatgtgctcc acaccaagat tttcaagtgg ttcaaacatc ttttcagcca attcaggtcc
    12901 actaatatta gcgtatcctg ggtaattttc gatatcagat gtattattca tctgaccacc
    12961 tggcagacca ccttcaatca aagctacttt tagattgctt cgagcagcat acaaggccgc
    13021 agtcatccct gcaggtccag caccgataat aatagtatcg tacatataga ttccttcttt
    13081 cttgttgtaa ctatctttat tctaactctt tcttgtcaat cacgcaagga ttatgccttg
    13141 aaaacaagaa ttaaactcat aaccgcaaag gataatactg ggacaaccaa gactccaatc
    13201 ataatcatat catagagatg ggcttggcga gccctggctg tcttatcaac tcccgacatg
    13261 gctctcagac caatccaaat ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa
    13321 ctctcgaaat ataaagaaaa tagttgcagt agcatgattt ctctcatttc tatctttttt
    13381 aaagagtaaa ctcagctagt ccaactaact gagttttcct ttatctatta tatcaaatat
    13441 aagtccgttt gtaactagcg aagaattctt ttgtccgctc ttctttaggg gtgtggataa
    13501 tctcatccgg tgttccagac tcgatgattt tccccttatc taagaagaga atcttatcag
    13561 ccacttgggc tacaaaggac atgtcatgac taaccaaaat catggtttga cctgacttag
    13621 cagcatctgc aatagacttt tctacttcac caaccaattc tgggtcaagg gctgaagttg
    13681 gttcgtctaa gagcaaaaca tctggtttca tagcaagcgc acgcgctagg gcaacccgtt
    13741 gcttctgtcc acctgataaa tggcgaggat aatggttttc acggtccgaa agcccaacct
    13801 tagccaactc ttccttggca atcttagtcg cttcttggtc agataatttc ttgacaacaa
    13861 ccaagccttc tttcacatta tcaagtgctg ttcggcgttc aaacaaatta aactgttgga
    13921 aaaccataga caacttacga cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat
    13981 caactgaaaa accatcaatc tgaatagagc cactgtcagg tgtttcaaga taattgagac
    14041 tgcgaagaaa ggttgatttt ccagctcctg aagaaccaat caaggctaca acttcccctt
    14101 tttgaatatc caagtccaga tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat
    14161 ttgaaatctt aatcattaac gaaggtctcc tttcacatct gtttgcactg tatcaggtgc
    14221 agaaatagcc atttttctct cgatgaaacg accgaggctt tcaattccga tattgaccac
    14281 ccaataaaca agggcaacgg agatgaagcg ttcaaaatag cgataatcag ctccacctag
    14341 aatctgagct tgggcaaaga cttccacaac acccgcacta aaagctagag atgttccctt
    14401 ggtcaaaccg atgagggaat taatcaaggt tggagtagct accaccgctg cattaggaat
    14461 aatcactcgt cgataaactt gcgctcgggt catacccaga ctgcgtgccg cctcaatctc
    14521 accaggatta actgagagaa tggctgcacg aatggtttca ctagcataag ctgcctcatt
    14581 aaaggcaaag gcgacaatcg caaaagctgc agctggaatc gcattgatat tgagaccagt
    14641 tccccattgc tgattgaggg ctttcaaagc caaagggatt ccgtagtaga tcaacatgag
    14701 ttgcaccaaa atcggtgtcc cttttaagaa actaacaaag aaggcctgca agggatataa
    14761 aatcttgaca cgattgatct tcacaatggc aaaaagaagc gccaaaacca agccaaaaag
    14821 ggcaccacca attgtcaaca taattgttgt tggaagttgt tggacaattc tagggattcc
    14881 atcaaagacc gaacgtaggc taaacagctt gccatccgga atcaattgca tcaagttttg
    14941 gtaccaatct gatgctaaaa tcgttgtaac attcataaaa acatcctctt ctgataatga
    15001 ttcattctac catgcttctg ccgtcaatga aactatttgc tacggtcaga tacagacttt
    15061 gtctacctac tagtttatca tactttgaaa cagggaagtt atatatttta tctatcaaag
    15121 agatagataa aaactatttc agtcccagtt cttcataaga ttttcgataa ccgatttgct
    15181 taacagttcc attttctact aaaataggcc gttttaacaa cataccgtca cttgctagca
    15241 actcagccgc ttcttggttt gacaaacttc ctaccttatc ttttagccct aattcacggt
    15301 atttgatacc actggtgttg aaaaattgct tcaattcaaa tcctgaggtt tctagccaat
    15361 tcaaaatgac ttcttggcta ggtgtttctt ccacgatatg gacggcttta tagtccacac
    15421 ctaattgatt taattcttgt tttgcttttt tacaagttga acatttggga tattcgataa
    15481 attctaacat gtgcttctcc ttctattgtt tctatcttta aaatctactc cttcatgctc
    15541 caagagccaa gctttctttt ccactcctgc agcataacct gtcagacgct tgcctgctcc
    15601 caacacacga tgacaaggta ctaggataga ccaaggattg cgtcccactg ctccaccaat
    15661 tgcttgagca gaagccactt gcaggtcttg agcaatttgt ccataggtca ctgtctgacc
    15721 ataaggaatg ccctgtaaat agtcccaaac tctcttttca aaattcgttc caattggcgc
    15781 caagagcaag ttggataaat cctgaggctt gcctttaaag taatcatcta agcaagcaat
    15841 aactgggtct aaaataggat gactaacaac ttcttctatc gtttcatctc ctagtcccct
    15901 ctcaaaatgc ttctgctcct gaacccaaat tccatacaaa taatggtcat cagctacaag
    15961 tgatagaata ccaattggtg aggagtagag gatttttaca tacttctttt gcattatttc
    16021 tttaattttt gataggccaa gcgttcgcca tctactggca ccttaccaac ttgtttaaaa
    16081 ccaagttttt caaaaatatg ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa
    16141 tcaagataat caaaaccttc aatcaagccc tctaagaagg tttgagcaac tccttttccc
    16201 tgcacatctg ctgccacagc aatacggtga aagactagat actctgactc tccagcttgc
    16261 cagtttccct cataaatagc ttcataggcc tcctctgaac tcttggtcac agcagcatag
    16321 gctagcagtt ctccctcttc caaggctacg taggcttgcc ctgagatgat atcatcgata
    16381 ataacatctg catttggata gccattttgc cactggtcac taccagcatc tgctaaacat
    16441 tttttggcat cctccatcac ctgcatgatg gcatctactt catttagaaa agctaaacga
    16501 atttccatct tttttcctca tttctgacta gtttctccca tcatagcata atttaagtat
    16561 ttctacaagc agttaaaact tgactttgtg tttttgttat tttataatct agttatcaaa
    16621 actatataaa aaggagttga aaatgaaaac taccttttcc tacccaaaat gggcagaaat
    16681 tccaaacatt gacctctatc tggaccaggt tttgctctat gtcaatcagg tctgcgcccc
    16741 tatctctcct aataaagaca agggcctaac agcatctatg gtcaacaatt atgtgaaaaa
    16801 tggttacctg acaaagcctg acaaaaaaaa ataccaacgc caacagattg cccgtttgat
    16861 tgctatcaca accctcaagt ctgtattttc tattcaagaa atagcccaga cacttaatac
    16921 tctacaaact caagcaagtt cagaccaact ctacgatgct tttgtggact acatgaacca
    16981 aggaattgac ccagctaacc ctattatcca aaccagctgc caaaccgtta aactctatca
    17041 tcaaactcta gacttaatcg atcatactca agaggaggta atccaatgaa cactagtctt
    17101 aaactcagca aacaactcag ttttggagag gagattgcta atagcgtgac ccatgctgtg
    17161 ggtgcagtca tcatgcttat cttgctgcct atttcatcca tctatagtta tgaagcacac
    17221 ggatttttat cctctatcgg cgtttccatt ttcgtcatca gtctctttct catgttccta
    17281 tcatccacca tttatcactc tatggcctat ggttcgaccc acaaatatgt tttgcgaatc
    17341 attgaccatt ctatgattta cgttgccatt gccggctcat acacgcccgt tgtcttgacc
    17401 ttgatgaata actggtttgg ctatctgatt attgtcatcc aatggggaac gaccatcttt
    17461 ggtattctct ataaaatctt tgctaaaaag gtcaatgaga aatttagcct tgctctttac
    17521 ctgattatgg gctggttggt tctggctatc attcctgcca ttatcagtca aacgacaccc
    17581 gttttctgga gtctcatggt aactggcgga ctctgttata cagttggagc tggattttat
    17641 gccaagaaaa aaccttattt ccacatgatt tggcatctct ttatcctagc tgcgtccgca
    17701 cttcaataca tcgctattgt ttattacatg taaaaaagtt gagaaattca atctcaactt
    17761 ttttctttac acatattgat aaagtactgg tgcaagcgca catcatcagt caattctgga
    17821 tgaaaagaac ttaccaacat atttttttct tgggctgcaa caatttgatt gttcactgtt
    17881 gctagaattt ctacaccctc accaacacta ctgataatcg gaccacggat aaaggtcatt
    17941 ggaatcttgc caactccctt acattctgct tccgtgtaga aacttcctaa ttggcgccca
    18001 taagcattac gctcgaccac catatccata gttcctagat gactctcttt ctgagaagtg
    18061 atttccttag ccagcaaaat taagcccgca caggtcccaa acactggtaa gccagataga
    18121 atggcttctc ggatgggaag tagcatgttc tggtcacgta agagcttgcc catggttgta
    18181 gactcaccac caggcaaaat caaacccgac aagtcactct gatcttgctg aaaatcatct
    18241 agatttctga gttctacact ctcgacacct aattgatcta gcacttttgc atgttctgca
    18301 aaggcccctt gcaaggccaa tattccgatt ttcatctatt ttcctcgttc agccatgaga
    18361 atttggattt cattttcatt aataccaacc atggcttctc ctaaatcttc agagatttga
    18421 gctaggattt gaggattacg gaagttagtc acagccttaa caatggcact cgctcgttta
    18481 acaggatctc ctgacttgaa aatacctgaa ccgacaaaga ccccctctgc ccctaattgc
    18541 atcattaacg cagcatctgc tggcgttgca acacctccag cagcgaaatt tacaactggc
    18601 aattttccat gttcatgaac atattggacc aattctacag ggacttgcaa atccttggca
    18661 gcaacataaa gctcgtcctc acgtaagttt tgaatgcggc gaatttcctg attcatcata
    18721 cgcatatgac gaacagcttg gacgatatcc cctgtccctg gttctccttt ggtacgaatc
    18781 atggaagcac cttcagcgat acgacgcaag gcttcaccca aatccttagc accacagaca
    18841 aaaggaactt ggaattcttt cttatccaca tggaaacggt catcagctgg agatagaact
    18901 tcactctcgt cgatataatc aatttcaata gcctctaaaa tctgagcttc aacaaaatgc
    18961 ccgattctga ccttagccat tactggaata ctaaccgctt cttggatttc cttaatcatc
    19021 tttgggtcgc tcatgcggga aactcctcca gctgcacgaa tatcagccgg aattcgttcc
    19081 aaggccatca cagctgccgc accagcagct tctgcgatac gagcctgttc aggattctgc
    19141 acatccataa taacaccacc cttgagcatc tgtgccaaat ttttatttag ttcataacga
    19201 ttttcagtca tttgttttat cctcatcatt tgtattggta gctacctttt cattttaagt
    19261 cagaacagaa tgaagcacaa gataaaaaaa ctataattgt atggggacaa attagctaaa
    19321 aactatctga ccttaactta aggccagata gctcattcat ttttattttt cagccgtaag
    19381 ggcagccatt gtgatgtagt tgtatggttt gttgaagtgt ggcaagaaga agaggtctgt
    19441 caatgccaat ttatcaattg tcacatgctc ttggatagca agtgagaaca tgtggattcc
    19501 catgctaatt gcaatatcat gtgaaaccat ttgggcacca agaatttcac ggctatcttt
    19561 gtcaaagaca atcttaattg ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg
    19621 aagatcgtta aagcctgttt cagttgcgtt gtaaccagca gctttcgctt tttcaagagt
    19681 caaaccagtt gaaaccatgt gaagaccgta gattgagata ccatttgaac cttgaacacc
    19741 gattccttcc aattcatgtc cacaagcgtt gtaggcacca acgataccag tgcgaacagc
    19801 atttgaagca agagcgatat agcttgtatc tttacgagca ttgtcataaa cagtcgcaca
    19861 gtcaccaaca gcgtaaacgc ctgggataga tgtttcttgt ttcttgtcta caaggaaggc
    19921 accgttgcgg aagagttcga tcttaccatc tgcaagggct gtgtttggac ggaaaccaac
    19981 tgcaaggata accatatcca cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt
    20041 accgtcacct tcgattgctt taacagtttg acctagagcc aagcggatgt tgtgatcttc
    20101 caagttcttc gccatcattt gtgtgaagtc tttgtcatag taaccgttca agacagtatc
    20161 aacgatatca acaaggacaa cttcttttcc aagacgttca aaggcctcag caagttcaac
    20221 accgatgtaa ccaccaccaa caacggcgat acggtcgagg tgttggctct tgtcagaaag
    20281 tttattgata acttcttcag cattttggta caatttcacg aattgtacgt tttcaagagt
    20341 tgctttaaat tcgcggtttc ctttaacaat ttcaacacct tcgattggtg gcaagattgg
    20401 tgtagaacct gtagcgaaaa tcaatttttc gtatgattct ttgtgctctt ttccttcaac
    20461 ttccgctgta actactttgt tatcatagtc gattgaaaga acaggtgagt tcatgtaaac
    20521 tttagcacct ttagcttcca atttttcttt atcagaatag aacaagcctt cagcaccgtc
    20581 aatttgttca ccaatccaaa gagccattcc acatcctagg aaagagatgt tagagttttg
    20641 gtcaaataca acaatttcgt tctcatttcc aaaattatcc aacatggtat tgatacatgc
    20701 tgtaccagcg tggttagcac cgactacaac gattttactc ataaaaaatt tcctgccttc
    20761 attctaaatt taccttacta gtataccatt taccgttagc gtttacaagg ggggtactat
    20821 catttcagca ttttttatca aaaataattc cccatttatc ctgttttcaa gcctgatgaa
    20881 ttttatgagc atatttcttg actttttcca aattttgttt gtgaaaattc taactttatg
    20941 gtattataat aacatgaaaa tgaaaggtaa gggcttcaat ttagatgatt atttgatatt
    21001 acaacttatt ttctataaga gaaaggagtt ggtagcttga ctcttcgttc acattctgaa
    21061 cggctaatgg ggactactat cactatttca ttagtggatg agcaagccga tatctttctc
    21121 caaaaatcct ttgacttgct caaagaactt gaataccgct tcaacgccaa tagtcaagaa
    21181 tctgagttga tggaaatcaa ttatcaagca ggaatagccc ccgtcacggt tcatccagac
    21241 ctgtttgagc tgatttcact tgggttagag catagcctag cgctctctag ccacctcaat
    21301 atcagcattg gtcccttaat tcaaacctgg cgtatcggtt tttcagatgc caaggtcgcc
    21361 cagcctcaag aaattgaatc ggtgctgcct ctaatcaatc ctcatggtat caagttagat
    21421 tcttctactt ctactgtgtt tttaaaacag aaaggaatga agatcgatct aggttgttta
    21481 gccaaaggat acagtgcgga taaggttgcc caatttctta ggaaagaggg ggtgacttct
    21541 gccttgatca atctgggagg gaatatcctg accattggaa aaaatcaggc aagaggggat
    21601 aacccatggc aaatcgggat tcaagaccca gccaatccta ggggaaatca tttaatgacc
    21661 atccctgttg tcaataaatc tgtcgtgact tcaggcattt atgaacgtca cctgaccgtc
    21721 gatggacaag attaccatca catttttgac agtcaaacag gatatcctgt tgaaacggaa
    21781 ctagcgagtc taacaatcat ctctgataaa tcagtcgatg gcgaaatctg gacgactcga
    21841 ctctttggag aaagacctgc ttctatcctc tggcaagtcg aaagtttgga gggcatcgaa
    21901 gtcatcctca tcgataaaga aggccaccta agctgttctt caggaattcc tactctatag
    21961 agacaactgt ttcaatggaa ttttaaaatt gtattatgta aaaagagaaa ggaaatctca
    22021 tgttaaaact tattgctatt gttggaacaa attcaaaacg ttctacaaac cgtcaattgc
    22081 ttcaatacat gcaaaaacac tttactgaca aagctgaaat tgagcttgtt gaaatcaagg
    22141 ccattcctgt cttcaacaaa ccagctgaca agcaagtacc tgctgaaata ttggaaattg
    22201 ctgctaaaat cgaagaggct gatggcgtta ttatcggtac tcctgagtat gatcactcta
    22261 ttccagctgt tttgatgagc gctcttgctt ggttgtctta tggtatttac ccacttttga
    22321 acaaaccaat catgattaca ggtgcttctt acggtacgct tggttcatct cgtgcccaat
    22381 tgcaacttcg tcaaatcttg aatgctcctg aaatcaaggc aaatgttctt ccagatgaat
    22441 tcttgctctc acactctctt caagcattta acccaagtgg cgacttggtt gaccttgatg
    22501 ttatcaagaa attggatgcc atctttgatg acttccgtat ctttgtaaaa atcacagaaa
    22561 aattacgtaa tgcacaagaa ttacttcgca aagatgctga agactttgac tgggaaaatt
    22621 tgtaagatag gagaccaaaa agaatgaaat ttgttggact tgttggatca aactacgatc
    22681 aatcatataa ccgtaagctc ttggaattta tccgtcgcta cttcaaactc aaatttgaat
    22741 tagaagttct tgaaattgac gaagttccaa tgtttaacca agatgaaaaa tgggatgaaa
    22801 gtttccaatt acgtttcttg tataacaaga ttacacgtgc tgatggtgtc attatcgcca
    22861 ctcctgagca caaccacact atctcagctt cactcaaatc tgtacttgaa tggctttcat
    22921 acgaagttca tccatttgaa aacaagcctg ttatgattgt gggtgcatca tactatgacc
    22981 aaggaacatc acgtgctcaa gttcaccttc gtaaaatcct tgatgctcca ggtgttaatg
    23041 cctacacgct tccaggtaac gaattccttc ttggtaaagc taaggaagct tttgataaca
    23101 acggaaatat caccaacgaa ggcactgtta aattccttga aacttgctta gataactttg
    23161 ttaaatacgt aggagtcgtt tcgaaattga aaaaaccaaa accaatcgaa tcagaagact
    23221 tagattgtgg aaaaccaatc gctacaacca tcacagaagt tgaccctgac gatccagaat
    23281 gggtagaaaa agttgcagca atcactggtg ctgtttctgg tgatacctat gtcaaattgg
    23341 accacggtat cctaacagtt aaccaaattg atatgttctt gaaagctatg ccatttgaat
    23401 tgacatacgc tgacgacaac aaccaattcc tctactacaa caacgctcac caagatccag
    23461 acactatgtt cgctaaacgt gtaccacctc aatcaggtag ccgtatgtcg actgttcatg
    23521 gttctcttcc accagcacgt atgaagaacg tagagtgggt tatcggaaca cttcgcaacg
    23581 gaaaccaaga atacgtccgt acgatcgttc caggttctcc tgcaggtgtt atcaacactc
    23641 acaactacca agcaatgtac tatcctgatg gatcatacgc tggtatcaat gaaatcgtct
    23701 ttaacttcca accatggctt gactggtacc taaaagagac tggtcaacgt ttggtgggtg
    23761 gtagcggacc atttgctcct gctgccggag atcatggaga cgccgatgct acttctggcg
    23821 cttctgattc aggggatgct ggaggccacg gtggtgacgc agacgctaca gccggtgcaa
    23881 gttactaatg atagttttta ggaaccatta tggttccttt tttagcgaaa aaagactaac
    23941 aaacacaaac tgctagtctc tttgttatcg tttcatctat ccttgttaaa agaaagaata
    24001 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gtacttaagt
    24061 acggcaaggt gaagctgacg tggtttgaat ttgattttcg aagagtatta ttatgaattt
    24121 gggtcatcaa gactacggcc atgtaatcct ttttcacgtt gtacttggcg tagtttttct
    24181 ggtgtaacat cgtttccttc ttcgtccaca attttgattc cttcaatgtg gtgacgaaca
    24241 gcgcggcgat aaccttcgat gtactcctca cgtagtttgg cttgttccac tttttcttct
    24301 ggtgttaagc cttctgtttt tttcttttta gcaagctcat tgatacgagc aatttttttc
    24361 ggatccattt cttctccttt gtaataagat aaagtccgtt tatcaaattt tatttagtgt
    24421 taatttggtt aaaacaagca aacttagctg ctttcttggt tagttgtgac aagattgcca
    24481 aacgattttg acggacagcc tgatcttcag ccattaccat agtattttca aagaaagcat
    24541 caatgactgg gctaagcgca aagagttgtt tcaattgctg acttgcaggt cctgataaaa
    24601 cgagtgtttc tactgcttct gccaaagctt tttcttggtc attctcaaat agtgctgaat
    24661 caactgtagc aaccccttct gccttctcag ccaggttaaa ggcacgagaa agtgattcaa
    24721 cagatggttt aaaatcttct tccttgctta cttctacgag agcacttgct gcttccaaca
    24781 tatctgccac aacaaagttt gaacctgcaa gaactgcttc cttgatatct tttggagtag
    24841 agcccatcat cttatcaaca cgagccttga taaagtccat aacctctgct ttattttcat
    24901 aagtcaaact gtcaaatttc aatgcataaa ggctatcaat cagctcatcc atagcaatgt
    24961 gccaaccaaa ggcatccaag atacgaacca caccttgagt tgcacgacga agggcataag
    25021 ggtcattaga acctgatgga atcaatccta ctgagaagaa actcaaaatc gtatccaatt
    25081 tgtctgcaat ggctagaact gcgccgacct tgctctctgg aagttctcct tcagctgatg
    25141 taggcatgta gtgttcacga atagcagctg ccaccgctgg agtttcacca gcaagaaggg
    25201 tgtatttttc acccataatt ccttggagtt cgtcaaattc accaaccata cctgtcaaca
    25261 agtcaaactt gtaaatggct gctgcacgag caaggtcaac tgtttcatcc actgacaaac
    25321 cagctttttc tgccaaaagt acagtgattt gacccgtacg aatcatgtgt tcacgaaggg
    25381 aaccaatctt ctcatggaag gtgacattgt ttaatttttc aacaagatct gaaatcacca
    25441 atttttggtc ttcacgccag aagaattctc cgtcttccaa gcgggctacc aagacttttt
    25501 catttccttt gatgacattt ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt
    25561 ttggcaagag ttttccatct tgatcacgaa caacaaagta acgctggtgt tccttcatag
    25621 aagtcaccaa gacttcttct ggaacttcaa ggtatttagc atcaaaactt cccatgaagg
    25681 cagttgggta ttcaaccaaa ttcaagactt cattcagcaa atccgcatca atttcgatac
    25741 gtacaccatg ttttgcctca atttccttga tttggtcaac aatcatttgc tcacgttcac
    25801 atggatctgc gattacaaac tgcttacgaa ggtcttcttc atagctcaat gctgactgaa
    25861 ttttggtttc tttccccaag aaacgatggc cacggctcac acgacttccc ttgatatcaa
    25921 ggaaatccaa gtcaaactct tgctcatcca agagaacagt taaagtgtga acagggcgga
    25981 tgtattcaaa gctatttcca gcccagtgca tgctgacagg gaaagtcaat gacttcaaga
    26041 catctacaac accaggaaca atggcttcaa ctgcttgacc aacttcttcc ttagtgacat
    26101 agacatattc ttcacccttg atttcacgga attcgatatc ttcaacagtc aagccttttc
    26161 cacggacaaa tccttgagct gctttggtga agtttccatc actatctaag gcaattttct
    26221 ttgctggacc cctgaaatct tctgtcaaat cagactgttt gtctgcaaga ccagttacac
    26281 gaacagccaa acgacgtggt gttgagaagg tttgaatggc ttcaaaagac aggcgttttc
    26341 ccttgaggaa ggctgccatt ttttcgccta gttgtttttc acttggcgta acaacatagg
    26401 ctggtaattc ttcaagaccg agttctacta ataagttttt tgtcatgttt tttctccgaa
    26461 aagtatcttt ttattttcca gtttgcctta tgtgattggc acgcaagcaa ccaacttcgt
    26521 tgtttcattg ctaaaattgg agccaaaagt ctccaatttt gcctagtatc cttagtttca
    26581 ctaaggatac cttcatcact gcggcaactg gctcagggct cactctgttc gcccattttc
    26641 gtaatttgtc actctcttta ttctgcgtct tctgctagga gtttagctct tgtttcttca
    26701 tccaaaagtg ggtagcctag gcgtttgcgt tctgcgacaa aggttttggc tacgacacgg
    26761 gccaagttac ggatacgagc gatatagcct gcacgctctg ttacagatac ggcaccacgc
    26821 gcgtcaagca gattaaaggt atgtgaacat ttgagaacat agtcataggc agggtgtacc
    26881 aagccttctt ctaatgcacg accagcttct ttttcaaact tatcaaagtt ttcaagcaac
    26941 atttcttggt ccgaaatttc aaatgaatat tttgagtgct catactcagg ctggataaag
    27001 atttctccgt attttacacc atcagcccac tcgatatcat agacagagtc tacttcttga
    27061 atgtaagaag ccaagcgctc caaaccatag gtaacttccg cagtcacagg gccagttgcc
    27121 aatccaccga cttgttggaa ataagtgaac tgagtgattt ccattccgtc aagccaaact
    27181 tcccaaccaa gaccagctga accagttgat gggttttccc agttgtcctc aacaaaacga
    27241 atatcgtgct ccaaaggatt gattcccaat ttttccaaag actcaaggta aagttcttgg
    27301 atatttgatg gagaaggctt catgaccacc tggaattggt ggtgttggta gagacggtta
    27361 gggttttccc cataacgacc gtcagcagga cgacgtgatg gctctacata agctgcattc
    27421 catggctcag gtccgatagc acgaaggaaa gtgtaaggac tcattgtccc cgcacctttt
    27481 tcattatcat aagcctgcat aagcatacaa tcttggtcat tccaaaattg ttgcaaagtc
    27541 aaaataattt cttgaaatgt taatttctta gacattgaat actccttaat aaaaaataat
    27601 ttcttgcgac acgagtctgc ctcgtcgatt atacgaggca agacgagtta gtactgcgtc
    27661 tagctcaggc actctagtgc tgagcgtagg gcagtccgac tgtaaggagg tttctgccac
    27721 tgacgcagtg aaatgttaat ttcttagaca ttgaatactc cttaataaaa aataattact
    27781 tgcgacacga gtctgcctcg tcgatcatac gaggcaagac gagttagtac tgcgtctagc
    27841 tcaggcactc tagtgctgag cgtggagcag cccgactgta aggaggtctc tgccactgat
    27901 gcagtgaaat gttaatttct tagacattgt ttactccttt agtttttata tttctttttc
    27961 aattaatttc tgctgaacaa accaatctaa caagggaaaa gttttttctg tatttgccca
    28021 taaatgataa gaatctaaga ccgcttgtac actacctaaa ttttctacca acttatctac
    28081 tgtcaaaaag ctgcgccagt attcataaaa aatacttgca tagttcttat cataagtcga
    28141 agaaccaaaa tcattcaatg aatgccaact atacttcttc tgaaaaagtt ctacgagaga
    28201 ttgattacaa attttttccg cttgaaattc ctcttctgtc aagaaatact tgcgactaat
    28261 atattcaacc atcccctctt cgaaccagat ataagagtca taaccatcaa aatcatctaa
    28321 aaaatgtccg accaatgagc taactcatgt cctacaatct gtaagaggaa attttcagat
    28381 aaagaatgat agtgactttc tattgcttga gtttgctcag aacactcgta gtccatcaac
    28441 tgatacaaat acaattcttt ccaaacagct aaatcaggcg tcataaccac tcgtctatta
    28501 tttgtatagg ttggaacagc actttcccta ataatctgtg tagcagcatt aaaatctgac
    28561 caaataacag cttgcggtaa atcacagact gcaagttcat tctttaaaaa agattgataa
    28621 tctttcaact tttcagtatt tcttactaca aaatcacgaa atgtagctag ttgactatcg
    28681 tcttttacaa gataaaggtt gtccacggct ctcctttctt tcacacaata gactgaataa
    28741 gcaaaagaac cacatctgac aatcctaggt tgatttaacc taggggcgtc agaaacgcgg
    28801 ttccacccta atttattact tcattgtttt tgaaaatact acagaaagcg ccagcccttt
    28861 attttgccct acttggctcc cactatccca agttcgcttg aagaacgcca taagactttc
    28921 tttcctgctg actattatat caaaaattag aataatgtac aattcttttt atgattttct
    28981 agaaatccac atcatcaact cgtggagcac ccgattgaac agcaatcgtt tttaaggttt
    29041 ctctctcctc atgactcagt tcaattccaa agcaatcaag attagcttga atacgagagg
    29101 ttgtgacaga ttttggaagt ggtaaaaatc cttctgccaa gctccaggcc aaggctatct
    29161 gagcaaccga ttttccgtga tttgctgcta tttcttggac ttgcttgcta tcaaacagtt
    29221 ctccttgtcc aaaaggcccc caagcttcca ataaaattcc cttttcacga cagtaagcta
    29281 cgacttgatc ttgatacaca cctggcgcca agcgaacttg attgaccgca ggaacgatag
    29341 ttgcagtttc aagcaaggca tccaaatgat ggggaagaaa attgctaacg ccgatagcac
    29401 ggattttccc ttcttgatag aggtcttcca tcgctctcca aacttccgca ttgcgagttt
    29461 tccatgcgtc attttctctg agcggttttg ggttcggcca atgaatcaaa tacaaatcca
    29521 aataatccaa gcccagtttt tctatagatt tttccaaagc ttgacgagtt tgctcatagg
    29581 tttgctgact attccaaagc ttggtagtta cgaacatttc ttcacgtgga actccgctat
    29641 ctttgattgc ttgaccaaca ctttcttcat tctgataaat cgccgccgta tcaatatgac
    29701 gataaccagc cttcaaggct tctaacactg cacgataggc ttcttctcca tccttagcct
    29761 taaaagttcc aaatcccaat actggaattt ctactccatt atttaattga taggtattca
    29821 tatgcttctc cttctatttt attcatcaat tatagcataa aacatttttt aagtagtact
    29881 atattctgta aaaaataagt ctgtcaaata tctaacagac ctattttttc ttgcttattc
    29941 atcacgacta tagtacagct catgagcttt taggcgagta ttgagcatct ctggtatggt
    30001 cacaaaggta taaccttgat ttttcaaata ctcaatgacc cttggcaagg cattgactgt
    30061 cggactgtga atatcatgca tcaaaacgat agagccatta gctacttgat gctgaatttc
    30121 tgtcaaaata gatgcttcat ttttactctt ccagtccaga ctatccacat cccacatgat
    30181 aaagctcaaa tccaagctat tgcgaatatc atctgtaata gcaccataag gtggacgcat
    30241 gagtttagaa ctagaaccca gcactttagt tagcacatcc tcagtatcag taatctgctt
    30301 tttagcttca tcaagagaga gttgcgagag aatcggatgg ctccagctat ggtttccaac
    30361 aacatgacct tcagatttta tcctcttcac caagtcctca ttcccagaaa catttttccc
    30421 aagcacaaag aaagtcgctt taatatcata tttagctagg gtctctaata cctgcggggt
    30481 cgttgctgga tttggaccat catcaaaggt tagagcgaca actttttgat gtttcttatc
    30541 aaagtaagat tggtacaagg ccgcatcttt ttcgagtaag tacgaagatt ggataacatc
    30601 aaagaaagca gatactggca aggctatctc ttctaaattt tcaaccacag gacttggata
    30661 aaggataatc tgactatcct tgtaatcaaa attccatgca gacaagtctt ggtcagagaa
    30721 gttttttaca atctgctcac tctggtcttg ctctattttt ttatcctcta tgaaggaggt
    30781 caactctttt atcagctgtt ccttagcctt actagcatct gaaaacagtt ggtcaagtgt
    30841 aaaaggttgc ccatcttctg ttaagtgaac ctttcctaga ctggtctttt cagtctcttc
    30901 aatcttaaaa gcaactaaat catagatttg tttggtcaca ttacgattaa cgactccctt
    30961 taaacctgac tcttcttgct ctgtatagta gaaaacaaga ttgtccttac tttctagctt
    31021 gtccttaaca tcttgattta tcagctccct aacagaggaa atcactttct ccccttggag
    31081 aggataatag gcaatcactt cggcttgccc ctgacgaaaa tgctccttct gatttccctc
    31141 actcaattga tcatctttct cttttttgag cgattcaatc ttttgctcaa aacttttttg
    31201 ctggtagatc ttaaaagcaa taaatccgcc taataggcaa atagaaattg ctaaaatacc
    31261 aatcaaagcc aataatacat gtctcgtttt cccgtgtctg ccacgtccta gtctactttt
    31321 attcatattt atatcataac aaatttgagc aataatttca atgatacaat ttggcaatcc
    31381 acaattcctc tagcaagcca aagcatctta catcaactcc aacatccgta tctgtagaga
    31441 ttatgtagtt ttctatctat ggaatttcta gtagattgaa gctagaatag tagacctata
    31501 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttctcatt
    31561 tcattttact ataaaactat gaaaagctag gtcatctgag aagtaattac tatcgacaat
    31621 tgcgatagcg tatactagtg cgatttgttt gtagctctgg tgggtatcac cttcacgttg
    31681 gcgaattttt tctaggtttt gattaacctg actgcacaga taaggccata ggcgattgat
    31741 gaaaaaattc tgatgatgaa cctgaatttc gatgataact tggattccat tatctaactc
    31801 cgccaagacg tctatactag tatagaaatc ttacgctgag tagggcatgg aaggcaagac
    31861 gtgaatgtta cttccctcca aaatcgtcac attttttgct ggcaagtcca gcatatcgcg
    31921 gataaattga caaatcatta gttgggctga tacctagatg tctgagaatc ctccttttcc
    31981 tccttctatt atagcacatt tttaaatcta ggtttgctag attctatgct tctatctatt
    32041 tattcggaaa agaaagctaa tagcttattt gaaattttct cctctctgtt ggatagtccc
    32101 gtctatctat gttataatga aagaaggatt taaaatcgga aaaggagtat ttatgctaaa
    32161 attaggtgtc atcggaactg gcgctatcag ccatcatttc atagaagcag cccataccag
    32221 tggagaatac caactggtcg caatctattc tagaaaacta gaaactgcag caacctttgc
    32281 ttctcgctat cagaatatcc aactattcga tcaattagaa gtcttcttca aatcttcttt
    32341 tgatttagtc tatatcgcca gtccaaactc cttacatttt gctcaggcaa aagctgcctt
    32401 gtctgctggt aaacatgtta ttctcgaaaa gccagctgtc tctcaaccac aagaatggtt
    32461 tgatttgatt caaacagctg aaaaaaataa ctgttttatc tttgaagcag ctcgtaatta
    32521 ccacgagaaa gcctttacta ctatcaaaaa ctttttagca gataagcaag tgttaggagc
    32581 agatttcaac tatgccaaat actcttccaa gatgcctgac ttgttggctg gacaaacacc
    32641 aaatgtcttt tcagaccgtt ttgctggtgg agccctcatg gatttgggga tttatcccct
    32701 ctatgctgct gttcgtcttt ttggaaaagc caatgacgcg acttaccatg ctcaacagct
    32761 tgacaatagc attgacctaa atggagatgg tatcctcttc tacccagact atcaagttca
    32821 catcaaggct ggaaaaaaca tcacttccaa tcttccttgc gagatttata caacagatgg
    32881 aaccttgact ctcaacacga ttgagcatat tcgctcagct atttttaccg accaccaagg
    32941 aaatcaagtc cagcttccta tccaacaggc tcctcatacg atgactgagg aagtcgctgc
    33001 atttgcacac atgatccagc aaccagatct gaatctctac caaacttggc tgtatgatgc
    33061 aggctctgtt catgagctac tatataccat gcgccagact gctggcatta gatttgaggc
    33121 agaaaaatga aaaccaaact accgactgaa tggcaagaac tgagtgacca actcggtttc
    33181 caagaattca cccccattca aactcaacta tttgagcccc ttcttgctgg agaaaacctc
    33241 ctaggagtga gcaaaaccgg aactggtaag accctagcgt atctcctacc aagtcttctc
    33301 agactacaaa agaaaaaagc ccaacaactc ttgattctag caccaaatac agaacttgct
    33361 ggacagattt ttgatgtatg taaaacgtgg gcagaagcta tcggattgac tgctcaactc
    33421 ttcctttcag gttcaagtca gaaacgacaa attgaacgtc ttaaaaaggg gccagaaatt
    33481 ctgattggaa ctcctggccg tatctttgaa ctcattaaac ttaaaaaaat caagatgatg
    33541 aatgtggaaa ccatcatcct ggatgaattt gaccaattac tagatgattc tcagattcac
    33601 tttgtagaaa aaatcactca ctacgcacct cgtgaccacc aactgatcta catgagtgcc
    33661 acgaccaagt ttgaccaaga aaagattgtg ccgaatacac gcactattga tctctctgat
    33721 caaaaattgg acaatatcca gcatttctac atgcaggtag accaacgtca tcgagtggat
    33781 atgctacgaa aactggctca tgtagaggat ttccgtggtc tagtcttctt caatagcctg
    33841 tcagaccttg ggaatgccga ggaaaaacta cagtatcgtg atatattggc tgtttccctc
    33901 gctagtgatg ttaatgttaa atttagaaaa gtcatcttag aaaagtttaa agataaccaa
    33961 ctaaccctgc ttcttgcaac tgaccttttg gctcgtggaa ttgatatcga tagcctagaa
    34021 tgtgtcgtaa actttgatat tcctagagat agcgaaacct acacacaccg tgctggccgt
    34081 actggccgta tgggcaagga aggatatgtt attactctcg tcactcatcc agaagaaatc
    34141 aaaaaactta aaaagtttgc aagtatccga gaaattgtcc taaaaaacca agaactctat
    34201 atcaaataaa gccccattgc tctatacaca tccagtgtat ggagcttttt tataagcaat
    34261 tcaattttat actcatctgc tttcaaaaag cattctagtc catctccgat taacgatgga
    34321 ctttatcacc tccttctcca gtccttgtat gacatcttgg agttgattca tgacatcttc
    34381 caaagttcga aaggctttat tcttaaatcc acgtttacga atctctttcc acacttgttc
    34441 aatggggttc atctctggtg tgtacggagg aataaatgca aagccaatat tagtcggaat
    34501 ctttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa aataatcatc
    34561 tggataagct tgtgaaagct cttctaaaaa gacgttcatc cactcagtat tacatccacc
    34621 agctcttaag aaaaatgatt cgcctgtatg ggcatcaaca gctccataac aatagcgaaa
    34681 ttctcgtata tagtgactat ggacatgtgg acctactcct attggagacc aacaagatcc
    34741 cagtttactg attctaccga aaccagcatc atcttggtac atcaagcgaa ccttatgaaa
    34801 aggtctactg gttttaaagc gctttcttgt gtattgcccc ccaaaagtta gacaattaat
    34861 ttatccgaag gatttagttc tgtattgcac agggctaagt ccttttagtt ttatcttaat
    34921 tttcttattg ttgtaataat caatatagtc tataatggct tgttccaatt ggttaagtga
    34981 tttaaatgtt ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc
    35041 catcataccg ttgtctgggc tgtttccctt gcgtgacata gatgcttgaa ttcccttact
    35101 ctctaggaac cgatgataag aatcgtgttg atattgccag ccttggtcac tatggagaat
    35161 cgtattctcg tagtgcttct ctttgaatgc ctgttccaac attgtttgta cttgttctaa
    35221 attaggcgaa caagaaagat taaaagcaat aatttcactg ttaaagccat ctaaaactgg
    35281 tgataagtaa agcttttgag tacttgctgg aatggcaaat tctgtcacat ctgtgtagca
    35341 cttttccatt gttttagagc cttcaaattg tccttgaatg agattctctg ccttcttgcc
    35401 aacgtctcct ttatgagaag aatattttcg tttctgtcgc attttagctt gtaaattgag
    35461 tacttttatc aagccttgaa ctcttttatg atttaccaga taaccacgat ttcttagttc
    35521 taaataaatc cgacgataag cataatttcc cttgtgttcg ataaaaatgg attgaatttc
    35581 agctttaagc tcttggtcct tatctggttt atctagctgt ttcaagtgat agtagtaggt
    35641 cgaacgagct agtttaatgg cttttagaag aatatctaac gaaaactcag tcattaattc
    35701 ttgaataatt tctgtctttc ttctttctct ttttcctcct tcaatcggag ttctcttaac
    35761 ttttttagga tggcattctc cgctctcagg tactctccct cttgttttct caacaatagt
    35821 atacccgttt ttcctgtatt gtgctagcca gttaagaagt atcgtacgac ttgggagacc
    35881 gtattcaaga gaaactctat ctttagtcca gccttcatgt cagactttat gaatcatttc
    35941 ttgttttaaa tcaggagaat agtaacgatt ttttcctttt ttgacgaact ctattccgta
    36001 acgatcaatc aatttaatca tgtacctaag attagaattg tttatcccaa atttatttga
    36061 aagcttctct aagctatatc cttgttttct aagttcatag atctgaactt tatcatcata
    36121 agttaatttc ataataaaaa caccccaaaa gttagatttt ttctgtctaa cttttggggt
    36181 gcagttcact tgtcttcttg aattgagact ttatttttag acgcgacaat ggtttgagca
    36241 tctgctttcc taggatgttc tggacgtggc gtaatatttc gccaaccatg gcgcttcaac
    36301 agttgataga aggcatcacg tgtgtaggaa cgacctaact cctttttata agcatggtta
    36361 cgaccaccac gtgtttcttg aaggagagag tcgagtccga actcctcata ttttttacat
    36421 ttcgccaaat cgttgtttga ttacagtcta aagtgtattg aatctataac agtacacctt
    36481 ggctgctaaa atatttctat aaattagttt gactttcctg atagagttgt tcacatctta
    36541 tttcaaacca ctataaaagt tctataatct ctttataaga tttgcccatc agacgaaata
    36601 gaacgatttg aaggcgttta tgatatttag ctgtacgaga gtcttttaaa agtgttttga
    36661 tggtttggat ttcttcttta atcgatttca tattactatt gtataatgct ttttgatttt
    36721 agtctagtat tatactcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat
    36781 agatgttact gacttcgtca gttctatcta caacctaaaa acagtgtttt gagcagtctg
    36841 tagctaactt tctatagtaa aatgaaataa gaacaagaca aatcgatcag gacagtcaaa
    36901 tcgatttcta acaatgtttt agaagtagat gtgtactatt ctagtttcaa tatattatag
    36961 tttgctcttt gattttcatt gagtattagt tcaatatcta aaaaaagaac cttgccaagc
    37021 aagattcttt tagtgtctaa cttaaataat tgttcttctg ggaactaaat cgaattaagc
    37081 ttcgatttct gtaaccatac ctgaaccaac agtacgtcca ccctcacgga tagagaatgt
    37141 agtaccttgt tctacggcga ttgggtgaat caactcaacg tcgattgtca cgttatcacc
    37201 aggcattacc atttcagtac ctgctggaag ttcgattgaa cctgtaacgt cagtagtacg
    37261 gaagtagaat tgtggacggt agttgttgaa gaatggagtg tgacgtccac cttcttcttt
    37321 agtaaggatg tagacttcac ctttgaattt agtgtgtggg ttgattgaac ctggtttagc
    37381 gataacttgt ccacgttcga tttcatcacg ttgaacacca cgaagaagga cacctacgtt
    37441 atctccagca agaccttcgt caagttgttt acggaacatt tcaacaccag taacaactgc
    37501 tttttgagtt tcttctttga taccaacgat ttcgatttcg tcgttgactt taacgatacc
    37561 acggtcgata cgtcctgaag caactgtacc acgtccagtg attgagaata cgtcctcgac
    37621 tggaagaagc aatggtttgt cagtgtcacg ttctggttct gggatatact catcaactgt
    37681 gttcatcaat tccataacga tgtcttcgta tttagagtca ccttcaagag ctttaagtgc
    37741 tgaaccttgg ataactggaa gatcgtcacc tgggaagtcg tattctgaca ataggtcacg
    37801 gatttccatt tcaaccaatt caagcaattc ttcgtcgtca accaagtcaa ctttgttcat
    37861 gaagacgata aggtgtttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg
    37921 tggcattggt ccgtcagttg aagctactac aaggatagct ccgtccattt gagcagcacc
    37981 agtgatcatg tttttaacgt agtccgcgtg tcctggagcg tcgatgtgag cgtagtgacg
    38041 tttttcagtt tcgtactcaa cgtgcgcagt gttgatagtg ataccgcgtt cgcgttcttc
    38101 tggagcagca tcgatagacg catagtcttt aggttggtta actgatgaag gcaagcgacg
    38161 tgccaaaaca gttgtgatag ctgcagttag ggtagtttta ccgtggtcaa cgtgtccgat
    38221 agtaccaatg ttaacgtgtg gtttactacg atcgtatttt tcttttgcca tttgagtaaa
    38281 agcctccaat aaaatatatt ttatagatag acagtaggca atacagtcta actttcctta
    38341 ctattttatc aaatttcagc taaattgcaa gtgttttaca acgtttttgt gaattattct
    38401 tggtaaaaat ttaactaatt aatagaaagt actaaataga cttatccttc aaggagtttt
    38461 cagcattatc catccactca cttgctgaaa atgtaaacag tctctggttt atatagtaaa
    38521 atgaaacaag aatagggcaa atcgttcagg acagtcaaat cgatttctaa caatgtttta
    38581 gaagtagatg tgtactattc tagtttcaat ctactataca acctcaaaac tgtgttttga
    38641 acaacctgcg gctagcttct tagtttgccc tttgattttc attgagtata aaattgcaga
    38701 taaaacgata acaatcatag gactcagcag agtcaatgta ggtcgaagaa tagcccccct
    38761 aatcgcttat tttatagtaa aatgaaatag aaactgaaca ttttgttgag gaaggtaaat
    38821 caattcctca caatgtttga gaaagaaggg aggactattc caacttcaac ccactataaa
    38881 gcagacttac aagataggga acccatctcc gataatattc cgataatata tagtagaatg
    38941 aaaactgcac aatttgattg gagaattcaa accaatttct cacaatgttt tagaaacaag
    39001 ggtctattat ttcaactgca acctactata gtccattgaa gctggaatag cccactgaga
    39061 cttctaaacc actgctggag aggagtttgt ttagagtttc tttcatttcc ctaaaaaatc
    39121 aaaaagagag aaccagtctg atcctctctt acttatagat ggtgctcact caaatgttaa
    39181 aggagctatt tcttagagat aaaggaattt gaatacagct actgccgcaa ttgctgctgc
    39241 gataggtgct actactggta cccaagaata ccaccatttt gaatcgcctt tatgctcacc
    39301 aagaactgat ttgggaagga aagcatgaag gagacgtggt cccaagtcac gggctgggtt
    39361 caaggcaggt cctgtaggtc ctccaagtga tgttaccaaa gccataacga ggaatccaag
    39421 tgccaagtga gccacagaaa gtcctgaagc agtgtgtgga gccacctgtg ctttaatagc
    39481 caagtcagaa aaatcaactg tttgtcctgc ttctgttgcc ttttgtttca tgaattgaag
    39541 cacttcagca ccaaagaagt ttttagtcaa accaagagct gcaaagaaca aaacaaatga
    39601 accaacaaac tcattaatca aaccattgac agttgctgca tagcgacttt cttttgtacc
    39661 atggtcaata cttgaaatag ttgagaaagt tcccaagatg ttatttgggt tttcagtttt
    39721 caagtagaat ggacggtatg ttgccacaac taaggcttgg ccaaagatag cccccaagac
    39781 ttgcgcgata atgtaaggta ccacttgtgc ccaagggaaa agaccgctaa ctgcaagccc
    39841 tagagtgaaa gcagggttga tgtgattccc agatacgtta ccaaacatca aggctgggat
    39901 cataaccccc ataccataac caacagcgat gacgatccag ccactttggt gacctttcgt
    39961 acctttaagt tcaacgttgg caactgcacc attcccaaga atgatcaaaa tggcagttcc
    40021 caaaaattca gtggcatact tcagtgccca tgtgaaatcc atttgctaga ttctccttaa
    40081 aattttttag atattcctta ttttatcaat ttttacccta tttagcaact gatttctgga
    40141 aatattttta aaaaaatagg attcatagtt tcccagttca acagacttgt aagcgttttt
    40201 attctttacg aaagacctcg ttctcaaaac caggaaaaaa gcccacatct gtgagctttt
    40261 cctggttcct agattctaaa atctattatt tttcatcttc ttttttcttg aaaaatccta
    40321 atcctagacc agctaacaag gtcatgatac cagcactagc caaggtagca ttagcttctg
    40381 tacctgtgtt tggcaattcc tctctcttac ctgtctcata agtcggaact tctgggtctg
    40441 gattcactgg agtttcagtt tttggagtac ctggttctgg agttggttta tctggtgttg
    40501 gagtctcttg atttggtagt tctgggtttg gtgtcggaac acttggatgc tctggatttg
    40561 gttgtgggat tggtttttct ggtgttgata aacggtcata ccttaccgtt atttctttat
    40621 cactagagtc tgacgtaact tcttgtgatt caactgttgg aatatctgga tctttgtact
    40681 tgtcaatctt accagatata acctcgtccc agtttcctgt tgtccattca ccgtaggtta
    40741 caactcccgt gaccttgttc tcagtttttg tacggcttaa ggttacaggt tgaacaacat
    40801 cttcttttac attttggttc gtaactttat caacgtaatg aatgatacgc gttatagtct
    40861 tcgtctcagt agaggttgct gttttgggaa ccactgtttc ctcaacattc tcacggtagt
    40921 aatagtcaac tgttgcaccg tcttctggta cgcatttgca ggagttgcta ccaaggtgta
    40981 tgttgttttc cttgtgataa ctcggtcttc tttgtcctca gttgttgttt tcccttcaat
    41041 agtttttgat tctgtggtat actcagaacc tatcgctaaa tcagctttta taacagactc
    41101 taccaacttc tcttgcctac cttctttata gtaattggct gttactgtag cagtggttgg
    41161 cgcttcgctt tctctataaa ctaaggtcac tgttctacct tcgcttacaa tattcccagt
    41221 taaacttgca gaatttgtat ctgcttcttt aaaagtataa tattttccgt cagtagtagt
    41281 catgctactg agttttttat ctgtgacatt atagctggta ccaatcagtt gttttttatt
    41341 ggtaatgtag gttccgtcac tttctttttc tccaattcca gtatcatttt tcaatgatag
    41401 caaacgccct tgttcatcaa catagcgaac tttcacattt tctgagatta gttctgccaa
    41461 ttctgaggtt tttttctttt tcttgatttc ttcggttatt ttccctttct cttcttcggg
    41521 aatatttagt tttggaatga ttttttcaac aacggttcgt gatggttcca cagtatcttg
    41581 gatgactgaa aagtcagcta gaattgggag attatactga acacggtgac tttgagtgtt
    41641 tactcctact ctttcattat tctctgaaaa tacttgtacg gtataagaaa caacatcttt
    41701 tcctaataga acatccccag tagagaaata gccgcctttt cctagtttgc tatctccaga
    41761 gcccacttct ttcctaatct tatcagatag ttttttacca gtcagtacat tcgttcgcac
    41821 aatccctttg tctaccccta caaagtggga gaactttttg aactcttcag aaccagatct
    41881 agcccaacca ttattaaggg catttgcttt tgtatttgta ttctctctca aaagtttggc
    41941 gattagaatt atattcatcg gcacttagag ttgctgctat atctgactct tgaataccaa
    42001 cttccttact accatttcta gcggcagtat atgtgtattt atctgtttct acttctagct
    42061 gattatcctt aacatgatag gtaattttct cctggtataa gagtcttcag tagtttatat
    42121 gctctgtcat catctttagc tttagaagca gctgagttta gccaagttgg ggtattagga
    42181 gtatctttat cagcctgttt caagacatta ttcaagtcat ttgctagcct attggttgtc
    42241 ctcactgtga aagttttctt ccagtctgaa ccacttttat tagacttaga tatgctcatg
    42301 aaatcctggt caacattcaa cacaatatcg ccttgttttt tagcatcttc cgttgcttct
    42361 gcttcaaatt gatcatggag tttttgttgc tctggtgtat agttttttta tttacacgat
    42421 ttaatgtact attttttatt ttagtattaa gaactccatt aatacgattt ttaaactctg
    42481 cttcaaaaaa tcccttaatt tgttggtgcg caagttcaac attcaaacct tttttataca
    42541 agtcttcatt ctgaacgatt tcggctacac ggtgaatggt ttgattgtat accgtcttct
    42601 cttaaccagc agtatcctta gttttaatga ctactcgata ggttccttta gaaccgttat
    42661 agtcatctag ttttaaaaaa gcattccaaa cattcaaaaa tagttggaac ttcccttaat
    42721 aaatccgtca ctttcttttt caagatagcc caagcttgct caataggatt caaatccggt
    42781 gaataaggtg gtagaggtaa gaaaaagtgt ttatcttgga tgcagagttc atccaaaatg
    42841 ttcttgggat gaaaaccagc attgcccatg acaataacat gaggtgtctt caaagcaggt
    42901 aggagttgcg ttttgaacca ctccacaaag aaatcgcttg tcatgctttt cttgtaaatc
    42961 atgggagcta taaactctcc gtctacttgt cctgcaacaa ttgaagttcg ctcaaaacga
    43021 cgtccgctaa tcttttcata gactttctcc cctctaggag cccctgcata aggacgatag
    43081 agatagcggt cgattcctgt ttcatcaata taaacaggtg ctaggtgctt taaactatta
    43141 aaattcttaa gaaataaggc tacttttctg ggtcttgttc cttaaagctc gtcatctttt
    43201 tttaaagtga ccttaatctg ctttaaagct gcccatactg aaggaacagc acaatcaaaa
    43261 tgtgccgcaa tttcccgtaa aaaagcatct ggatgagcct ctacaaaggc tttcaattcc
    43321 tctaaaggaa tctttcggtt tttgacgact cgctttttcc tctcta
//
LOCUS       DAVLHB010000012        43226 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLHB010000012 DAVLHB010000000
VERSION     DAVLHB010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.012"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            115..2007
                     /gene="pepO"
                     /locus_tag="VXE36_000762"
     CDS             115..2007
                     /gene="pepO"
                     /locus_tag="VXE36_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0779106.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2130..2759)
                     /locus_tag="VXE36_000763"
     CDS             complement(2130..2759)
                     /locus_tag="VXE36_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0779107.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            3775..5997
                     /locus_tag="VXE36_000764"
     CDS             3775..5997
                     /locus_tag="VXE36_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0779108.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6027..6470
                     /locus_tag="VXE36_000765"
     CDS             6027..6470
                     /locus_tag="VXE36_000765"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0779109.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6737..6923)
                     /locus_tag="VXE36_000766"
                     /pseudo
     CDS             complement(6737..6923)
                     /locus_tag="VXE36_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7087..7737)
                     /locus_tag="VXE36_000767"
     CDS             complement(7087..7737)
                     /locus_tag="VXE36_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0779110.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            7849..8691
                     /locus_tag="VXE36_000768"
     CDS             7849..8691
                     /locus_tag="VXE36_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0779111.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            8767..9204
                     /locus_tag="VXE36_000769"
     CDS             8767..9204
                     /locus_tag="VXE36_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0779112.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            9272..9574
                     /locus_tag="VXE36_000770"
     CDS             9272..9574
                     /locus_tag="VXE36_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779113.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(9665..10738)
                     /locus_tag="VXE36_000771"
     CDS             complement(9665..10738)
                     /locus_tag="VXE36_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0779114.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            10894..11571
                     /locus_tag="VXE36_000772"
     CDS             10894..11571
                     /locus_tag="VXE36_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0779115.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            11564..12538
                     /locus_tag="VXE36_000773"
     CDS             11564..12538
                     /locus_tag="VXE36_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0779116.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(12587..14530)
                     /gene="thrS"
                     /locus_tag="VXE36_000774"
     CDS             complement(12587..14530)
                     /gene="thrS"
                     /locus_tag="VXE36_000774"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0779117.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(14588..14911)
                     /locus_tag="VXE36_000775"
     CDS             complement(14588..14911)
                     /locus_tag="VXE36_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0779118.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            15770..16399
                     /locus_tag="VXE36_000776"
     CDS             15770..16399
                     /locus_tag="VXE36_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0779119.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            16540..16809
                     /gene="rpsO"
                     /locus_tag="VXE36_000777"
     CDS             16540..16809
                     /gene="rpsO"
                     /locus_tag="VXE36_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0779120.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            17625..18239
                     /locus_tag="VXE36_000778"
     CDS             17625..18239
                     /locus_tag="VXE36_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0779121.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(18531..19280)
                     /locus_tag="VXE36_000779"
     CDS             complement(18531..19280)
                     /locus_tag="VXE36_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0779122.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            19413..21749
                     /locus_tag="VXE36_000780"
     CDS             19413..21749
                     /locus_tag="VXE36_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV0779123.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            21851..22528
                     /locus_tag="VXE36_000781"
     CDS             21851..22528
                     /locus_tag="VXE36_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0779124.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEEADQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEFLVVEVGEM
                     ELSARDTRFGPFLSREISPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHASK"
     gene            22515..23312
                     /locus_tag="VXE36_000782"
     CDS             22515..23312
                     /locus_tag="VXE36_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0779125.1"
                     /translation="MLASEVIKRYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVTEAIEKGVDLIIVKHAPIFRPIKDLVASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNVQSQTFWELTQQVKQVFGLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGAEVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAELLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            23329..24432
                     /locus_tag="VXE36_000783"
     CDS             23329..24432
                     /locus_tag="VXE36_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0779126.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            24733..25752
                     /gene="galE"
                     /locus_tag="VXE36_000784"
     CDS             24733..25752
                     /gene="galE"
                     /locus_tag="VXE36_000784"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0779127.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRSGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            25754..26707
                     /locus_tag="VXE36_000785"
     CDS             25754..26707
                     /locus_tag="VXE36_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0779128.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(26769..26975)
                     /locus_tag="VXE36_000786"
     CDS             complement(26769..26975)
                     /locus_tag="VXE36_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0779129.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            27027..27503
                     /locus_tag="VXE36_000787"
     CDS             27027..27503
                     /locus_tag="VXE36_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0779130.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            27512..28183
                     /locus_tag="VXE36_000788"
     CDS             27512..28183
                     /locus_tag="VXE36_000788"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0779131.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            28313..28651
                     /locus_tag="VXE36_000789"
     CDS             28313..28651
                     /locus_tag="VXE36_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0779132.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            28654..29283
                     /locus_tag="VXE36_000790"
     CDS             28654..29283
                     /locus_tag="VXE36_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0779133.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            29523..30674
                     /locus_tag="VXE36_000791"
     CDS             29523..30674
                     /locus_tag="VXE36_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0779134.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            30987..31736
                     /gene="truA"
                     /locus_tag="VXE36_000792"
     CDS             30987..31736
                     /gene="truA"
                     /locus_tag="VXE36_000792"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0779135.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            31726..32499
                     /locus_tag="VXE36_000793"
     CDS             31726..32499
                     /locus_tag="VXE36_000793"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0779136.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            32477..32938
                     /locus_tag="VXE36_000794"
     CDS             32477..32938
                     /locus_tag="VXE36_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0779137.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(33197..33400)
                     /locus_tag="VXE36_000795"
     CDS             complement(33197..33400)
                     /locus_tag="VXE36_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779138.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(33393..34475)
                     /locus_tag="VXE36_000796"
     CDS             complement(33393..34475)
                     /locus_tag="VXE36_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0779139.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(34601..35383)
                     /locus_tag="VXE36_000797"
     CDS             complement(34601..35383)
                     /locus_tag="VXE36_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0779140.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(35383..36726)
                     /locus_tag="VXE36_000798"
     CDS             complement(35383..36726)
                     /locus_tag="VXE36_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0779141.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADLQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(36838..38154)
                     /locus_tag="VXE36_000799"
     CDS             complement(36838..38154)
                     /locus_tag="VXE36_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0779142.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            38347..39573
                     /locus_tag="VXE36_000800"
     CDS             38347..39573
                     /locus_tag="VXE36_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0779143.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            39772..41346
                     /locus_tag="VXE36_000801"
     CDS             39772..41346
                     /locus_tag="VXE36_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0779144.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIESLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            41611..42399
                     /gene="codY"
                     /locus_tag="VXE36_000802"
     CDS             41611..42399
                     /gene="codY"
                     /locus_tag="VXE36_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0779145.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            42399..42974
                     /locus_tag="VXE36_000803"
     CDS             42399..42974
                     /locus_tag="VXE36_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0779146.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            43056..43141
                     /locus_tag="VXE36_000804"
     tRNA            43056..43141
                     /locus_tag="VXE36_000804"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43090..43092,aa:Leu,seq:aag)
BASE COUNT        12396 a         8178 c         9871 g        12781 t
ORIGIN      
        1 atcatggaaa gattttttat aatagctaaa aaataatagt taaatggtta ttaattgcat
       61 tccctagtga tttttgttaa gataaatgca aatacaaatg aaagcgagaa caagatgaca
      121 cgttatcaag atgattttta tgatgctatc aatggagaat ggcaacagac agctgaaatc
      181 ccagcagata agtctcaaac tggaggtttt gttgatttag accaggaaat tgaagacctg
      241 atgctggcga caacagacaa gtggttagca ggtgaagaag tgcctgagga tgctatcttg
      301 gaaaactttg tcaaatacca ccgcctagtt cgtgattttg acaagagaga agctgacggt
      361 atcacacctg tcttaccact ccttaaagaa ttccaagaat tggaaacttt tgcggatttt
      421 acagctaaac tagcagagtt tgagcttgca ggaaaaccaa acttccttcc ttttggtgta
      481 tcgccagact ttatggatgc tagaatcaat gttctatggg ctagcgctcc aagcacaatc
      541 ttgccagata cgacctacta tgcagaagaa catcctcagc gcgaagagct cttgactctt
      601 tggaaagaaa gcagcgcaaa tctcctcaag gcttatgatt tctctgatga agaaattgaa
      661 gacttgctag aaaaaagact tgaattggac cgccgagttg cggcagtggt gctctctaat
      721 gaagaaagtt cagaatatgc taaactctat catccatatt cttacgaaga ttttaagaaa
      781 ttcgcgcctg ccctaccttt ggatgacttc ttcaaagcag ttattgggca attaccagac
      841 aaggttattg tagacgagga acgtttctgg caagcagcag agcaattcta cagtgaggaa
      901 gcctggtctc tccttaaagc aaccttgatt ttgagtgttg tcaatctttc aaccagctat
      961 ttaacagagg atatccgtgt tttgtctggt gcctacagcc gtgccctttc tggagttcca
     1021 gaggcaaaag ataaggtcaa agcagcttat catctagcac aagaaccttt caagcaagcc
     1081 ctgggtcttt ggtacgcccg tgagaagttc tctccagaag ccaaggcgga tgtggagaaa
     1141 aaagtggcaa ccatgattga tgtctataag gagcgtctgc ttaagaatga ctggctcact
     1201 ccagaaacct gtaaacaggc tatcgtgaag ctcaatgtga tcaaacctta tattggctat
     1261 ccagaagaat tgcctgcacg ttacaaggat aaggtagtga atgaaactgc cagtcttttt
     1321 gagaatgctc tagcctttgc gcgtgtggaa atcaagcaca gttggagtaa gtggaaccag
     1381 cctgtagact ataaggaatg gggcatgcct gctcatatgg tcaatgccta ctacaatcct
     1441 cagaagaacc tgattgtctt tccagcggcc attttacagg cgcctttcta tgacttgcat
     1501 cagtcatctt ctgctaacta cggtggtatt ggggcagtga ttgcccatga aatttcccac
     1561 gcctttgata ctaacggggc ttcctttgac gaaaatggta gcctcaagga ttggtggaca
     1621 gagagcgact atgctgcctt caaggagaaa acacaaaaag tcattgacca atttgatgga
     1681 caggattctt atggagcaac cattaacggt aaattgactg tatcagaaaa cgtggctgac
     1741 ttgggaggaa tcgcagcagc gcttgaagca gctaagagag aagcagactt ctcagcagaa
     1801 gagttcttct acaacttcgg tcgcatctgg cgcatgaaag gtcgaccaga atttatgaaa
     1861 cttttggcta gcgtcgatgt gcacgcacca gccaaactcc gtgtcaatgt gcaagtacca
     1921 aacttcgacg atttctttac aacctatgat gtcaaagaag gagacggaat gtggcgttca
     1981 ccagaggagc gcgtgattat ttggtaatac aaaaaatcta gtcatcagaa aaaaggcatc
     2041 caatcacgtg tgaaaacctt gataggatgc cttttgtaat agaaagattt gctggatagt
     2101 ttacttaaat ttcgattgtc atcatcttgc tagaaaaagg gattgaaggc cttttcgtga
     2161 gcgatagtag tagctggacc atgtcctgga tagacatcgt agtttggtag ggtgaagagt
     2221 tgggtctgga tactatgaag gagttgctcc atgctaccag tcggaaggtc ggtccgtccg
     2281 atagtttcgc ggaatagagc atctcccgtc aagactaggt gagcatcagg aaagactagg
     2341 gaaacaccac cgatagagtg ccctggggtc ggtagaacct taaaacgaaa ttcctctagt
     2401 tggtattctt cgtgaaagac aaaggtgtgt tctgcaggtt ttgtgaccac atctgccata
     2461 tcatcgtggc gagggagacc ggagagatta tcgacaggag tgtagagcca gctggcttcg
     2521 ctctctgcga tatagacagg aggattgcca aacgtctcgc gaaccaagtc cagactcatg
     2581 atatggtcat aatgggcgtg ggtcaagaga atagcacaga tcggtttgtt gatcttctcg
     2641 attgtctgac gaatggcttc ccaatgacta ccaggatcga cgacgatgag gtgcttttcg
     2701 ccttctagat aataggtatt ttcataggca acaggattca cggttttatg gattttcata
     2761 ctagctccaa tctcaaagaa tgtactaata ctcttcgaaa atctcttcaa accgcgtcaa
     2821 ctttatctgc aacctcaaag cagtgctttg aacagcctgc ggctagcttt ctagtttgct
     2881 ctttgatttt cattgagtat aaattaagta tagcacagtt agggagaata ggtaaggatt
     2941 taaaatgaac ttaaaaacca gcatgactag atgaagacag gctggttatc aatttatcaa
     3001 tattggaaag gtgtcaattg cccttcatag gttgcataaa ctccgtcatt agcttgtttg
     3061 atagacgtga tgtttagagt gctaccgtag ttggcttatc atttgtcgct atattcacta
     3121 taagttatcc tactgggcag gttctggtcg ttagcatagt attgaacgag ttttttatag
     3181 ctttgctggc tgaataggaa caggcagcaa actcctaaca ttaggagagc aaagatagaa
     3241 atagcagttt ttttcatagg tattctcctt ataaactaaa ggatagaaga aagtatcttg
     3301 aggattttta tactcttcaa aaatctcttc aaaccgcgtc aacaatctct tcaaaccgcg
     3361 tcaacgtcgt cttgccgtat atatgtgact gactttgtca gtcttatcta caacctcaaa
     3421 gcagtgcttt gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta
     3481 ttaattccaa aatccagtca aggtaccagt gtatgtgata cgagttccac cgtttatctt
     3541 tcgtatcttc aatggaattg gggaaatcag aaagtctttg ggttacaata tggtttccgt
     3601 tcttctatct ctccttctat cacctaagtt taaaatctaa cttcgtagta tattatgggc
     3661 caataattca gaattatcaa gcaattttga attatttttt tcttattctg ttccaatcta
     3721 gttttcatat tcttaaaaaa gtgataaaat ggtaggaaga attggagagt agagatgccg
     3781 aaagaagtga atttaacagg cgaagaagtt gtcgctttaa ccaaagaata tttaacggaa
     3841 gaggatgttc attttgtcca taaggccttg gtctatgctg ttgaatgcca cagtggtcaa
     3901 tatcgcaaat caggcgagcc ttatatcatt caccctatcc aagtggcagg tattttagct
     3961 aagctaaagc tggatgctgt aacagtagct tgtggattct tgcatgatgt ggtggaagat
     4021 acagatgcga ccttggacga tttggaaaga gagtttggtc ctgatgtgcg ggtgattgtt
     4081 gacggagtta ccaagcttgg caaggtcgag tacaaatcga tcgaggagca attagcggaa
     4141 aatcatcgca agatgctcat ggccatgtct gaggacatcc gcgttatttt ggtcaaactg
     4201 tctgaccgct tgcacaatat gcggaccctg aaacatcttc gaaaagacaa gcaggagcgt
     4261 atttccaaag aaaccatgga aatctatgcc ccacttgccc atcgtttggg gatttccagt
     4321 gtcaaatggg aattagaaga cttgtctttc cgttatctca atccaacgga gttttacaag
     4381 attacccata tgatgaagga aaagcgcagg gagcgtgagg ccttggtgga tgaggtagtc
     4441 acaaaattag aggagtatac gacagaacgt cacttgaaag ggaagattta tggtcgtccc
     4501 aagcatattt actcaatttt ccgcaaaatg caggacaaga gaaaacggtt tgaggaaatc
     4561 tatgatctga ttgctattcg ttgtatttta gatacccaaa gtgatgttta tgccatgctt
     4621 ggttacgtgc atgaattttg gaaaccgatg ccaggtcgct tcaaagacta tattgccaac
     4681 cgcaaggcca atggttatca gtctatccat acgactgttt atggaccaaa agggccgatt
     4741 gaattccaga ttcgaaccaa ggaaatgcac gaggtggctg agtacggggt tgcggctcac
     4801 tgggcttata agaaaggtat aaaggggcaa gttaacagca aggaatcagc tattggaatg
     4861 aactggatca aggagatgat ggagctccaa gaccaggctg atgatgctaa ggaatttgtg
     4921 gactctgtta aggaaaacta tttggctgag gagatttacg tttttacccc agatggagct
     4981 gtccgttccc ttcccaaaga ttcaggaccg attgattttg cctacgaaat ccataccaag
     5041 gtcggtgaaa aagcaactgg tgccaaggtc aatggccgca tggttccact gacaaccaag
     5101 ttaaagacag gggatcaggt tgaaattatc gccaacccga actcctttgg acctagccgt
     5161 gactggctca atatggtcaa gactagcaag gcgcgcaata agattcgcca gttctttaaa
     5221 aaccaagata aggaattgtc tgtcaacaag ggtcgtgaga tgctgatggc tcagttccaa
     5281 gaaaatggct atgtggcaaa taaatttatg gacaagcgcc acatggatca agttctgcaa
     5341 aagaccagtt acaagacaga agactccctc tttgcggcca ttggttttgg ggaaatcggt
     5401 gcgattaccg tctttaatcg tctgactgaa aaggaacgcc gtgaggaaga gcgtgccaag
     5461 gccaaggctg aggcagagga gcttgtcaaa ggtggcgagg tcaaggttga aaataaagaa
     5521 actctcaagg tcaagcatga ggggggagtg gttattgaag gtgcttctgg tctcctagtg
     5581 cggattgcta agtgttgtaa ccccgtgcct ggtgacgata ttgttggcta cattaccaag
     5641 ggtcgtggtg tggctattca ccgtgtggac tgtatgaacc tgcgtgccca agaaaactac
     5701 gagcaacgtc tccttgatgt ggaatgggaa gaccagtact ctagctcaaa taaggagtat
     5761 atggcccata tcgatatcta cggtctcaac cgtacaggac tgttgaacga tgtactgcaa
     5821 gttctttcaa atacaaccaa gaatatttca acggtcaatg cccaaccaac caaggatatg
     5881 aagtttgcta atatccatgt gtccttcggt attgccaacc tctctacact gaccacggtt
     5941 gtcgataaaa ttaagagtgt gccagaagtt tactctgtca aacggaccaa cggctagttg
     6001 tcctagctct tactagaaag gctattatga aaatcattat ccaacgggtt aaaaaagccc
     6061 aagtgagtat agaaggccag attcagggaa aaatcaatca gggactttta ttgctggttg
     6121 gtgttggacc agaggaccaa gaggaagatt tggactatgc tgtgagaaaa ctggtcaata
     6181 tgcggatttt ttcagacgca gaaggcaaga tgaacctgtc tgtcaaagat attgaaggag
     6241 aaatcctctc tatttctcag tttaccctct ttgcggatac taagaaaggc aatcgtccag
     6301 cctttacagg ggcagctaaa cctgatatgg catcagactt ctatgatgct ttcaatcaaa
     6361 aattagcgca agaagtgccc gttcagacag gcatctttgg agcagatatg caggttgaac
     6421 tggttaataa cggacctgtt accattatcc tagatactaa aaagagataa gaaagaccaa
     6481 gcccagtcgg cttggtcttt ctcatcgatc ataaaatact ccaaaaagaa atcggttctt
     6541 gatatgcttg ggggaagtct cttttcaggc tttggcagat gcgataggaa gggatgagat
     6601 atcctaggat gaggagagtt ccctgaagga aaagtggaat atcacttaaa gacaccaagg
     6661 agagaatcat caggctatcc cataggagaa tttgtaaagc aaaacgccag aatctcggtc
     6721 taatctggga atagagttaa ctaaagtggt cacaaagttg gtttgaaaga taggtcaata
     6781 gcacaggatg aaagaaaatg agccaaccac tataaatcaa aatccagtcc caagtaagcc
     6841 ccccttttaa atgtcaaaaa tgccagcatg attccatcaa tgacaaggag ttgaatggtt
     6901 ttgatgaaga tgattttttt catgctaaaa cctccttttt tcatctgtta gtgacgtaat
     6961 gctttatata attattatac agtattcagt cgggatatga aaacgtttac tatcgttttt
     7021 gatataaaaa atagataaga aaaccctgaa aataaaactt tcagggttgg taggggactt
     7081 gagaaattag ttgattttct cgacatagag ttgttttgca atgtccatat tcacttgtaa
     7141 atcctcgtcg ttactgagga tagtgaaggt attgctgaag ccatcaaact gcttgacttg
     7201 gagctggtca ccgatgtgaa gtgagtgctt gtccagataa tggagaatgt caaaactatc
     7261 gtgcacccga gtcaggcggt aggcgccagc ttccttgata tcagctagtg ggaggttatt
     7321 gatttcaacg aggagttctc ccttggcagg aatagttcct ccgtgggggc aggttttagg
     7381 gaaacctagc agtttatcta gtctttccac gaacaggtca gagacagtgt gttccaagac
     7441 ctcagcttcc tcgtgaatct ggtcacttgt atagtctaaa tgatgaacta gaaaaacttc
     7501 aatcaagcgg tgcttacgat agagctcaga gaccagtttg agaccgaggt cagtcagtag
     7561 atagccacat tccttgtcct ttaggatgag attttcactt ttcattcgtt tgatcatttc
     7621 agttacggca gggggagaga cttgcatgcg agccgcaatt tccttgttgg taatcttatg
     7681 caggtctatg ccaatttcat aaatacattt tagatagtct tctttgtttg gggtcattcg
     7741 tttcctcttg tctaatatct ttatctagta tatcaaaaaa agctagattt ctctagctgt
     7801 gactttttat gttatactta ttgcaagaga aaaaacgagg agatggatat gacgaaaata
     7861 gctcttcttt cagatattca tggaaatacc accgccttgg aggctgtttt ggcagatgct
     7921 cagcagatag gagtggatga atactggctt ttgggagata ttctcatgcc agggacagga
     7981 cgtagaagga ttttggactt gttggatcaa ctaccgatta cggctagagt tttgggaaac
     8041 tgggaagaca gtctttggca tggtgtccgt aaggaattgg acagtactcg ccccagtcaa
     8101 cgctatctct tgcgccagtg ccagtatgtt ttagaggaaa tttccctaga agaaattgaa
     8161 gtgctccaca atcaacctct tcaaattcat cgtcagtttg gggatttgac ggtgggaatt
     8221 agccatcatc tgcctgataa gaactggggg cgagagttga ttcatactgg caaacaagag
     8281 gagtttgacc gcttggtgac tcatcctccc tgtgatattg ctgtttatgg acatattcac
     8341 cagcagttgc ttcgttacgg gactggtggg caattgattg tcaatccggg ttcgattggc
     8401 caacctttct ttttggacgc tcagctacgg aaggacttgc gggcccagta tatgattttg
     8461 gagtttgatg acaaaggcct ggtagatatg gacttccgac gggtagacta cgatgtggca
     8521 gcggaattgc agctggctaa agacctgaga cttccctatt ttgaggttta ctatgaaagt
     8581 ctggtcaatg ggatccacca tactcatcat caggaatttt tgagagaatt ggctcagaaa
     8641 gagggctgcg atcgggagtt agacgactgg ttgaaaagtg gtaacgattg acattacaac
     8701 taaaaagggt ataataatag aaaaagaaga gtagaggcag ggtagcctcg taaaaaggag
     8761 aagaggatgc aaattccaag tagatttacc attgcgactc atatgctgat aatcattgcc
     8821 ctcgagggga aggaaagcaa ggtgaccagt gattttctgg ctgctagtgt cggggtcaat
     8881 cctgtcatta tcagaaagat cttgtcccag ttgaagaagg cagagctgat ttcagtagcg
     8941 cgtggaacgg gcggaacaga gattgtcaag gaccttaagg atattagtct tttagatgtt
     9001 tatcaggcgg tcgaatgtct tggtaagaca ggtcaactct tcagtttcca tgacaatccg
     9061 aatccaaatt gccctgtagg agctcatatt catgatgttt tggatcaaaa attggagaga
     9121 attcagttga ctatggaggc agaacttggt caaaccagtc tagaaaaagt cgtggccgat
     9181 gcagagagtc agatgaagga ttaagaggga taaatgccct cttttttctt tggataatta
     9241 tgataaaatg tagctattaa aggagtaaga aatgtatctc gttataggaa ttgtattagc
     9301 ctttatagtg tcattttgga aggataatag aagtttgtgg aatccagtat tatttttatt
     9361 atccctcatt tcaagttatt tttatctatc ctaccttttt tataaaaatg gatacgagaa
     9421 tgttcagtta gctttttatg tatttgcctt tgtcttactt ccttttttgc tttttctaag
     9481 tggcatcttt ttaatctata atggggtcat tttgttgaag cgagagggac gttccaagcc
     9541 ccattatctc tcaatgctct ttgattttta ttgactatta gattctattt aaaaagactt
     9601 agaatgcaca tgaaagtatg tattctaggt cttttgtttt gtatacattt aattttcaag
     9661 agtattatct atttttccat gcctggtaac gagtatcaat caataactgg gtaaggcgac
     9721 ccaaggtttc tctttcttct ggagtgaggg attgagcttg gacaaagaga tgatgaatgt
     9781 attcaagcgc ctttaaggaa gccaagtcat tgatagagct aataccagcc tcaagaatag
     9841 tgccaaagaa gaggtcgaag tagagctgaa gttcttcgtc agggactgtg gccacccatt
     9901 ctttaaaggt tgtgtctact tgctggctat cactgttggt cttatccagt tggacgaagt
     9961 gcttgtcctc aatctgccaa ctaaaggtat cgtgctgggc gatgccaccc agggcagtac
    10021 tctgaacgat gatttggtga gcaggaattt ccagcatcat accgataatg gaaccttgtg
    10081 gaatgaatat cttgcttcta tccattatcc tttgataacc cgcagtctgt gtcaattctt
    10141 gatggagacc aggtgcatca aatgtataaa ctgctgtgat ctgattttgc aaactttgct
    10201 caatttggct agcagcatag atagcgagat ttcctccctt ggaatgccca gctagaataa
    10261 ccttttgctt aggatgatgg gcaaaaaagt tctttaaata gcgaagggcg tgcttttgag
    10321 caggaatttc cttcatatag gtcaggtgga aatcttcctt ccagccaatg atactgtcat
    10381 ctgtcccacg aaagacaatc agataggtat cgaggctgac acgataagtc atagccgcaa
    10441 attgcttttg cagttcaggg tcgatgtcgt tgataaaatg ggagagtttg caatttttga
    10501 agcgcttgtg ttgagccaat tcatctaata attgaaggcg atttttgcta gtaagcatgg
    10561 tgggatctct tggaacctga ggtgctagat ctaaaagacg ttgaggaagt gtggagacca
    10621 gattatcaaa ggagaggtag gtgatttcta ttaaggttag aatgtctaac tcattcaagg
    10681 gaaggtcgta ataagaatca tatgcgacat ctttcagata gtcaaaaata ttggccataa
    10741 gagctccttt ctttttattt atcttagcaa atttccctca aattagctag tagcatagcc
    10801 tgtttgtact ggctaaaaac aggctatttc aaattcagtt tcagaccatc tagcatggaa
    10861 aaatctgtta taataatgga aaaggagaag cgcatgcaca agattttatt aatagaagat
    10921 gatcaggtca ttcgtcaaca gattgggaaa atgctctctg aatggggatt tgaagtggtc
    10981 ctggtagaag actttatgga agttttgagt ctatttgttc agtcggaacc tcatctggtc
    11041 ctcatggata ttggtttgcc cttgtttaat ggttatcact ggtgtcagga aatccgcaag
    11101 atttccaagg tacctatcat gtttctttct tcgagagacc aggctatgga tattgtcatg
    11161 gcaatcaata tgggggcgga tgactttgtg accaagcctt ttgaccagca ggttctttta
    11221 gctaaggttc agggcttgtt gcgtcgttcc tatgagtttg ggcgtgatga gagtttgctg
    11281 gaatatgctg gtgttatcct caataccaaa tccatggatt tacattatca agggcaagtc
    11341 ttgaatttga ccaagaatga attccagatt ttacgcgtgt tatttgagca tgcaggcaac
    11401 atcgtagcac gtgacgacct gatgcgggaa ctttggaaca gtgacttttt cattgatgat
    11461 aataccctct ctgtcaatgt ggctcgtttg cgtaaaaagt tggaggagca gggattggta
    11521 ggatttatcg agaccaagaa aggaataggg tacggattga agcatgcttg attggaaaca
    11581 attttttcta gcctatctgc gctcccgtag tcgtcttttt atctatctgc tttctttggc
    11641 atttcttgtc ttactctttc agtttttatt tgccagtcta ggaatttact tcctctactt
    11701 tttcttcttg tgttgctttg taaccatctt atttttcact tgggacatat tggtggaaac
    11761 gcaggtctat cgccaggaac ttctctatgg agagagggaa gccaagtctc ctttggaaat
    11821 agctttagca gaaaaattag aagcgcgtga gatggaactc tatcagcaga ggtcaaaagc
    11881 agaaagaaaa ctgacggatt tgctggatta ctataccttg tgggtccatc agataaagac
    11941 ccccattgca gccagtcaac tcttagttgc agaagtggtc gaccgccaac tgaagcagca
    12001 gctagaacag gaaattttca aaatcgactc ctataccaac ctagttttac agtacctgcg
    12061 tttagaaagt ttccatgatg atttgctctt aaagcaggtt caaattgagg acttggtcaa
    12121 ggaaataatt cgtaaatatg ctcttttctt tattcaaaaa ggcttaaatg tcaatctaca
    12181 tgaccttgat aaagaaatcg tgacggataa aaagtggctg ctagtggtta ttgagcaaat
    12241 catctcaaac agtctcaagt acaccaagga aggtggtctg gagatttata tggatgacca
    12301 agagctttgt atcaaagata cgggaatcgg gataaaaaac agtgatgtcc tccgagtatt
    12361 tgaacgtggc ttttcaggat acaatggccg tttgacccag cagtcctctg gacttggcct
    12421 ttatctatct aagaaaattt ctgaagaact ggggcaccag attcgtatcg agtctgaggt
    12481 cggaaaagga acgacagtgc ggattcagtt tgctcaagtg aacttagtcc ttgagtaaaa
    12541 atagatgaga aaaagcctcc agattggagg cttttatgct agactcttat ttctcaacgc
    12601 gtgatttgtt ggcgatatca gctaggatag cttgaacaaa attatcaact gagacagttt
    12661 gtgtttcttt ttggccgtag cgacgaacgt tgactgtttc gtcttccatt tctttgtctc
    12721 caacaattaa ttggtaagga atcttgctgg tttgtgaagc acgaatcttg aactgcattt
    12781 tttcattgcg ctcatctacg tctgcacgga caccgcggtc acggagtttc ttggccactt
    12841 cccaagcgta gtccacgtgt ttttcgttag atactgggat gagggttact tggtgtggtg
    12901 ccagccatgt tgggaaggcc cccttgtagt tctcaatcaa gatagctgtg aagcgttcca
    12961 tagttgagat aaccccacgg tggatcatga ctggacggtg atcttcgcca tcagctccga
    13021 tgtatttgag gtcgaagcgt tctggcaaca agaaatcaag ttggatagta gaaagggttt
    13081 cttcttttcc aagggcagtt ttaatctgga tatccaattt tggtccgtag aaggctgctt
    13141 caccttcggc ttcaaagtag tccacgccca tttcatcaag agctgcacga agcatggttt
    13201 gggcattttc ccacatctca tcgttatcaa agtacttatg agtatcttga gggtcacgaa
    13261 gagagaggcg gaagcggtag tcagtcaagt tgaagtcttc ataaacatcg ataatcaact
    13321 gaagggcacg ttggaattct tcttggattt gttctggagt aacgaatagg tgaccgtcgt
    13381 tgagtgacat ttcacgtaca cgttgaaggc cagtgagggc accagatttt tcgtaacggt
    13441 gcatcatacc gatttcagcg atacggattg gcaattcacg gtaagagtga acatggtgtt
    13501 tgaaaacttg gatgtggtgc ggacagttca ttggacgaag gacaaattct tccccgtcac
    13561 ccatgtccat ggttgggaac atgtcttctt ggtaatgatc ccagtgacca gaagtcttgt
    13621 aaagctcaac agaagcaagt ggtggagtgt agacgtgttg gtagccagaa gccaactctt
    13681 tgtttacgat gtagcgttcc aattcacgac ggatagtcgc accatttggc aaccagaatg
    13741 gcaaaccttg tcccacttct tgtgaaatca taaagaggtc aagctcttta ccaagtttac
    13801 ggtggtcacg ttccttagct tcttcacgca tttgaaggta gtttttcaag tctttcttgt
    13861 caaaccaagc tgtaccgtag atacgttgca tcatagcgtt gtcgctgttt ccacgccagt
    13921 acgcaccagc tacatggaga aggtggaaga tttggatacg acctgttgat ggaacgtgag
    13981 gtccacggca gaggtctaca tattcaccct gacgatagat agtcaaaccg ccttcgtctt
    14041 ctgagtgttc ttcaatcaat tccaacttgt aagggtcatt tttgaagatt tcacgtgcct
    14101 cgtctttagt cacttcttca cgaatagatg ggaagttttc tttgacgatt ttttgcattt
    14161 cttcttcgat acgaggaagg tcttcgttag agatttgacc agctgtgttg tcagtatcgt
    14221 agtagaaacc atcttcgatg gctggaccaa ctcccaagtg aatgtctggg aaaagacgac
    14281 gagctgcttg ggcgaacaag tgagctgctg agtgacgcaa gattggaagg gcatcttcgt
    14341 gatcaggtgt cacaatttcg atgcttccat cttcagtgat agcgcgagta gtgtcgatga
    14401 gtttgccgtt gaatttacca gccaaggctt ttttagctag ggaattgctg atagattggg
    14461 caatttcaaa agttgttacg ccagattcga attcacgaac agcgccatct gggaaagtaa
    14521 tgttaatcat gatgttctcc ttttttatta tttcatagtt tctaagcatt gattttttat
    14581 cagcagacta cttccaagtc ctaacgttca attgcttttc tttatcagag aggaagtttt
    14641 ccatttccgt cagaatgtct atatccaaac gttgagaaag ttctaatagc caccagatat
    14701 tttctgaaag tttttgttcc agtgtgtagg gtgtttcatc atagtagcgt ccttgctttg
    14761 tcatcaccag tcgttggaaa tttccaatat cattagataa agccaagagg tcttcttcta
    14821 ccgtccactt gaaatcatga tgcttaactt ccagttcgtg ataagcttgt cggattgccc
    14881 aactgcgctc cactaattct tgcaactcca taattagtat cctaataaaa aaatgcgaca
    14941 tcctcgaaag gacgtcgcaa cgtggttcca ccttcattta tgtacctcaa aagagaggga
    15001 cacctctgat cggctctaac gtggccaccg ttttatgttt tcataaaaaa ctcaagagta
    15061 gtatcagttt agacttccta tgcgtttcca gcaaccacgc actctctagt agaaagggac
    15121 taagtgactt gtctctatgg attattatag catgattgtg agatttttca aggattttgt
    15181 gaaagttttt tgtttttcat attttgtaga atatgcttga tgctaatacc agaatccatg
    15241 cccaccagag caactgtttc atagattagc aagtaaatta gtataaactc accaaaggtt
    15301 atgatagtaa agtaaaagag cagtccgtta ccaactaacc atcaaagtga gaaacggaaa
    15361 cggtagctat agagtaacga tacaatcaag attaccagag gtgtaaagaa gagaagattg
    15421 tttatatagt gtaaaggggt cagaaacaac tagcaagaac aactcataaa gtggctaata
    15481 aaagaataat atgaccagat agtaggggag atgggaatag aatctacgca tgataatcac
    15541 ctcgttttaa aaaaacagac aacttagatc tcttgctatg attattatag catgtttaaa
    15601 acaagaaagt aaatttgttg acaaagaaga tttttctttt cactagaatc atagttagtt
    15661 ttcttggtag aaatattttg ataataatta agcaagacta ttgatattga ttattaagag
    15721 tgtcacattt gttgtaacta aaataattac aacaatagag gtataaaaaa tgaaactagc
    15781 agttattgca gcaaatggac aagcggggaa agcaattgtt gaagaagcag tcaaacgagg
    15841 acatgaagta acggctattg ttcgttctga aaacaaaagt caagctgagt ctattattaa
    15901 aaaagattta tttgagttga caaaagatga tcttactgga tttgatgctg ttatttcagc
    15961 gtttggtgct tatacaccag atacgctacc gctccacagc aaatcaatcg aactatttaa
    16021 tcagcttctt gctggaacac agacacgttt tctagttgta gggggagcag aaagtcttta
    16081 tatagatgaa acaaaaacga cacgactttt agatacgtct gattttcctg aagaatttaa
    16141 gtcactagca aaagctcaag cggatgaatt ggatcttctt cgtacaaaaa ataatctcaa
    16201 ctggactttt gtcagtcctg ctgtagattt tattcccgat ggtgaaaaaa caggaaacta
    16261 cattctagca ggagaaattt ttactactaa tgaaaaagga ataagccaga ttagttatgc
    16321 agattatgct attggattgg tagatgaact tgaaaaaggt catcatataa aagaacgtat
    16381 ctctttactt gaaaaataat aactatgaga gtattaatgt ttgacagaaa atttaaatct
    16441 tggtaaaata gggattgtcg taaagacaaa taacttcttc ttggttacag gcatgccaac
    16501 ctgtcactcg gatgaagcca aataaaaagg agaaacatca tggcaatctc aaaagagaaa
    16561 aaaaatgaaa tcattgcaca atatgcacgt cacgaaggtg atacaggttc agtagaggtt
    16621 caagttgctg tccttacttg ggaaatcaac caccttaacg aacacatcaa acaacacaaa
    16681 aaagaccacg ctacttaccg tggattgatg aaaaaaatcg gtcgccgtcg taacttgctt
    16741 gcatacttgc gtaaaaacga cgttaaccgt taccgtgagt tgatcaactc tctaggactt
    16801 cgtcgctaat tcaagataca aatgctgtca aaagcacaaa gcaaaaatag gaaaattgac
    16861 gaagaaactt cagtttctag gagattttat cttttttgcc aagtgcttag gccgtgttca
    16921 attgagcata tcttgataat gaagctactc taaattgggt agcttttttg cgttgtcacc
    16981 ttacctcgat atactcaagt ataatctttg gttacggttc ctagcactgt aaggtaaaat
    17041 aaaccagctt ttctcccttc ggggagattt tttttgtttc actgaaagtt tcgtacgatc
    17101 ttcgcctcgt cgcctagtct ataaacgatt tatctagcaa gaatcatgat gctaagggcg
    17161 tcaaaaatcc gtatgaaaat agggaaatga cacagtgttc gatgagcaca aggagtttca
    17221 tctttttcac taggatttta gcccgggctc aaatcagctc tctgacttca gagggctttt
    17281 ttattgaggt tttatcggta acaattttgg agactacaaa aacctcaaac ggtatcagct
    17341 aattacacca taaaggtgcg cagttactcg gcttttcaag ccgagtaact gtatgcaagc
    17401 cccctagaag agcccactct ttacaaagta aagtatagta tgttatactt tacatggaag
    17461 tagtcactga attccagtta gaaattactt tgtaactacg ttttgaggag gagtaaaatg
    17521 ctttcctacg ttcgacatta cccactagcg atagctaaat taatgtgtct gtgctctcct
    17581 aaaatctgct gatttattac tgactaatac aggaggtttt ttttatggga cagacaatca
    17641 tatctgctat tggtgtttat atttccacca gtatcgatta tttaattatt ttaattattt
    17701 tatttgcaca gctatcacag aataaacaga aatggcatat ttatgcgggg caatatctag
    17761 gcacaggctt acttgtaggg gcgagtttag ttgctgctta tgtcgttaat ttcgtgcctg
    17821 aagaatggat ggttggattg cttggtttaa tccctatcta tttagggatt cgctttgcaa
    17881 ttgttggaga agatgcggaa gaagaagagg aagaaattat tgaaagatta gaacaaagca
    17941 aggcaaatca actgttttgg acagttacat tgctgacaat tgcgtctggc ggagataatt
    18001 taggtatcta tataccttat tttgcttcgt tagattggtc acagaccctc gtggccttgc
    18061 ttgtgtttgt aatcggcata attatctttt gcgagattag tagggtgtta tcctctattc
    18121 cgttaatatt cgagacaatt gaaaaatacg agcgaatcat tgtgccctta gtattcattc
    18181 tacttggact atacatcatg tatgaaaatg gcacgataga gacttttctg atcgtgtaga
    18241 tttttttgtt tcactaggat tttagcccga gctcaaatca gctctctgat tttcagaggg
    18301 ctttttcatt gagtataaat ggacaatctt aaagttactc tattgtagag tggcttttga
    18361 tttgattagg agattcttat aaatatagta aaatgaaata agaataggac aaatcgatca
    18421 ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat tctagttcca
    18481 atctactata taaatgaaaa ccttagctgt ttggccaagg ttcatttctt ctatgcaagt
    18541 tcttctcttt tcttatctgg gttccagatg aagcttgcga taaagctaaa gatgatggtt
    18601 aggatagcga ggataatagc aaggatgagg gcagggatgc ggataaacca ccagagtgga
    18661 tttggttttt tatcattgtg ccattgtttc gtttcttcgt ccagacgttg gaattctgtt
    18721 tgaatacgat tggcgactgt ttcaatgcct tcatcattca ttttcttgat atctgagata
    18781 tcgattggat ttccaaagtt catatcgaca cgttcacggc taatcaagcc cttcaaagtc
    18841 atgggaccgg tgtaggtaac cggcatgata cggaccttgg ccattttggc aatcagtgct
    18901 gcgcccccct tgacatcgtt tgagtggcgg ctaccacttg gaaacatgat gagagagcgg
    18961 tcactttttt tgagaacgtt gataggatat ttgatggctg aggcgctggg attttcacgg
    19021 tcgatgggaa aggcgccaca catacgaatc caccaaccaa agatacggtt ggtaaagagt
    19081 tctttttttg ccataaagat gaactgtttt ggcttggtcg caaaggccat ataaacagga
    19141 tcccaccagg tacggtgagg cgcaactaaa atataatttt catcttgatt aggaatttta
    19201 tcagtattat gatagtgagc attgccattg atggaccata agagcagtac aactaatcca
    19261 cgcaaataag tataaaacat gcgatctcct tcgattgttt tcttgttatt attatacctt
    19321 atcaaaggag ggctggcaaa cttttccctt gactagatac atatttagga tgaaattaga
    19381 attctgttaa aaaaaatgat ataatagaat ttatggataa aaataagatt atgggattaa
    19441 cccaaagaga agtcaaggaa agacaggctg agggtttggt caatgacttt accgcatcag
    19501 ccagtaccag cacttggcaa atcgttaaac gaaatgtctt tacccttttt aacgctttga
    19561 acttagccat tgctttggct cttgcctttg tgcaggcttg gagcaatctg gtcttctttg
    19621 ctgttatctg ctttaacgct ttttctggga ttgtgaccga gctacgagcc aaacacatgg
    19681 tggacaagct caatctcatg accaaggaaa aggtcaaaac catccgtgat ggtcaggaag
    19741 ttgctcttaa tcctgaagaa ttagtgctag gagatgtcat tcgtttgtct gcaggagagc
    19801 agattcctag tgatgccttg gttttggaag gctttgcgga agtcaatgaa gccatgttaa
    19861 cgggagaaag tgatttggtg caaaaggaag ttgacggctt acttttgtca ggaagtttcc
    19921 tagccagtgg gtcagtttta tctcaagttc accatgtcgg tgcagacaac tatgctgcta
    19981 aactcatgct tgaggctaag accgttaaac ccatcaactc ccgtatcatg aaatcgctgg
    20041 acaagttggc tggttttact gggaagatta tcattccctt tggtctggct ctcttgctgg
    20101 aagccttgct tttaaaaggc ctgcctctca agtcatctgt tgtaaactcg tcgacagctc
    20161 ttttgggaat gttgcctaag ggaattgccc ttttgaccat tacttcgctc ttgactgcag
    20221 ttatcaagct aggtttgaaa aaggtcttgg tgcaggagat gtactctgtt gagaccttgg
    20281 cgcgcgtgga tatgctctgt ctggacaaga cgggtaccat cacccaagga aagatgcagg
    20341 tggaggctgt tcttccgttg acggaaacgt atggtgaaga ggctattgcc agcatcttga
    20401 ctagctacat ggcccatagt gaggataaga atccaactgc ccaagccatt cgccagcgtt
    20461 ttgtgggaga tgttgcttat cctatgattt ccaatcttcc cttctccagc gaccgcaagt
    20521 ggggggctat ggagttagaa ggcttgggga cagttttctt aggggcacct gagatgttgc
    20581 tggattctga agtcccagaa gccagggagg ccttggagag aggatcacgt gtcttggtct
    20641 tagctctcag tcaggagaaa ttagaccatc acaaaccaca gaaaccatct gatattcagg
    20701 ctctagcctt gctggaaatc ttggacccta ttcgagaggg agcagcagag acgctggact
    20761 atctccgttc tcaggaggtg ggactcaaga ttatctctgg tgacaatcca gttacggtgt
    20821 ccagcattgc ccagaaggct ggttttgcgg actatcacag ctatgtagat tgctcaaaaa
    20881 tcaccgatga ggaattgatg gccatggcgg aggagacagc tattttcgga cgtgtttccc
    20941 cccatcaaaa gaaactcatc atccaaacgt tgaaaaaagc gggtcataca acggctatga
    21001 caggggacgg ggttaatgat atcttggccc ttcgtgaggc ggattgttct atcgtgatgg
    21061 cggaggggga tccagcaacc cgtcagattg ccaatctggt tctcttgaac tcagacttta
    21121 atgatgttcc tgagattctc ttcgagggtc gtcgcgtggt caataacatt gcccacatcg
    21181 ccccgatttt cttgataaag accatctatt ccttcctgtt agcagtcatc tgtattgcca
    21241 gtgctttact aggtcggtct gaatggatct tgattttccc cttcattcca atccagatta
    21301 ccatgattga ccagtttgtg gaaggtttcc caccattcgt tctgactttt gagcgaaata
    21361 tcaaacctgt tgagcagaat ttcctcagaa aatccatgct tcgtgcccta ccaagcgctc
    21421 tcatggtcgt ctttagcgtc ctgtttgtga aaatatttgg gagtagccaa ggttggtctg
    21481 agttagaaat ctcaactctc ctctattatc tcttggggtc aattggtttc ttatccgtat
    21541 ttagagcctg catgccattt accctatggc gtgtcctctt gattgtttgg tcagtaggag
    21601 gtttcctagc cacagctctc ttcccaagaa tccaaaaact gcttgaaatt tcaaccttaa
    21661 caggacaaac attacctgtt tatggtgtca tgatgttggt ctttaccgtg attttcatcc
    21721 tgaccagtcg ctatcaagcc agaaaataaa gaaaggctgc aatctgtgga ttgcagtctt
    21781 tttaggtaca agattgccag ccgaaatgtg gtataataag aggtaataga gttttggaaa
    21841 gtgagagaag atgatttcaa agagattaga attggtggct tcctttgtgc cacagggcgc
    21901 tattttacta gatgtgggga gtgaccatgc ttatctgcct atcgagttgg tcgaaagagg
    21961 acaaatcaaa agtgccattg caggtgaggt ggtggaaggt ccctaccaat ctgcggtcaa
    22021 aaatgttgag gcgcacggcc taaaggagaa aatccaagtc cgtttagcca atggcttggc
    22081 agcttttgaa gaagcagacc aagtgtctgt cattaccatt gctggcatgg gtggtcgttt
    22141 gattgctagg attttagaag aaggtttggg gaagttagct aatgtagagc gtttgatcct
    22201 ccagcccaat aatcgtgaag acgacttgcg tatctggcta caggatcatg gattccagat
    22261 tgtagcagaa agcatcttag aagaagctgg aaagttttat gagtttctag tagtggaagt
    22321 tggagaaatg gaattatcag caagagatac ccggtttggc cccttcttgt caagggaaat
    22381 cagcccagta tttgtccaaa aatggcaaaa agaagctgag aagctagagt ttgccctcgg
    22441 acaaatccca gaaaaaaatc tggaagaacg tcaagttcta gtagataaga ttcaagccat
    22501 caaggaggtt ctccatgcta gcaagtgaag tgattaaacg ctatgaagcc ttttgccctc
    22561 aggaattttc tatggaagga gacagccgtg gcctgcaaat tggcacttta gacaagggta
    22621 tccaaagggt catggtggct ctcgatattc gtgaagaaac ggtgactgaa gccattgaaa
    22681 agggtgtaga cttgattatc gtcaagcacg cgcctatctt tcgtcccatc aaggacttgg
    22741 ttgccagccg tccgcaaaat cagatttata tcgacctaat caagcatgac attgcagtgt
    22801 atgtcagcca taccaacatt gacatcgttg aaaatggtct caatgactgg ttttgtcaga
    22861 tgctaggcat tgaggagacg acttatctac aggagacagg tcctgaacgt ggaattggac
    22921 gtattgggaa tgttcagtct cagacatttt gggaattgac ccaacaggtc aagcaagtct
    22981 ttggcctaga tagccttcga atggtgcatt atcaagagaa tgacttacag aagcctattt
    23041 caagagtggc tatctgcggt ggtagtgggc agtctttcta taaggatgct ttagctaaag
    23101 gagcggaagt ctatatcact ggtgacatct actaccacac tgcccaggat atgctgtctg
    23161 atggcttgct agcattggat ccaggacact atatcgaagt gctgtttgtg gaaaaaatcg
    23221 cagagcttct tactcaatgg aaagagaaaa aaggctggga actagagatt ttacctagtc
    23281 aagcatcgac caatcctttc cgtcatatct agttagaaag tgaagacaat gaaaaaagtt
    23341 gccattattg gagcaggaat tgtgggagca acagctgcct actacctctc gagagaaagt
    23401 gacctagagg tgaccgtttt tgaccatgag caaggtcaag ccaccaaggc cgcagcagga
    23461 attatcagtc cttggttttc caaacgccgt aataaagcct ggtacaagat ggcgcgcttg
    23521 ggggctgatt tttatgtgga tttattagct gatttagaga aatcaggaca agaaatcgac
    23581 ttttaccagc gttcgggagt ctttctcttg aaaaaggatg aatccaattt ggaagaactt
    23641 tatcaactgg ccctccagcg cagagaagaa tctcccttga tagggcaatt agccattctg
    23701 aaccaagcct cagctaatga attattccct ggtttgcagg gatttgaccg cctgctctat
    23761 gcttctggtg gagcgagagt agatggccaa cttttagtga ctcgtttgct ggaagtcagt
    23821 catgtcaagc tggtcaaaga aaaagtgact ctgacaccgt tagcatcagg ctaccagatt
    23881 ggtgaagagg agtttgagca ggttattttg gcgacgggag cttggttggg ggacatgtta
    23941 gagcctttag gttatgaagt ggatgtccgt cctcaaaaag gacaactacg agattatcag
    24001 cttgcccaag acatggaaga ttaccctgtt gtcatgccag aaggggagtg ggatttgatt
    24061 ccctttgcag gtgggaaatt atccttaggc gctacccacg aaaatgacat gggatttgat
    24121 ttgacggtag atgaaacctt gctccaacaa atggaggagg ccaccttgac tcactatctg
    24181 attttggctg aagctacttc aaaatctgag cgtgttggaa tccgtgccta caccagtgat
    24241 ttctctcctt tctttgggca ggtgcctgac ttaactggtg tctatgcagc cagtggacta
    24301 ggttcatcag gcctcacaac tggtcctatt attggttacc atttagctca actgatccaa
    24361 gacaaggagt tgaccttgga ccctgaaaac tacccaattg aaaactatgt caaacgagta
    24421 aaaagcgaat aatactcaat gaaaatcaaa gaacaaacta ggtaactagc cgcgggttac
    24481 tcaaagcact gctttgaggt tgtggataga actgacgaag tcagctcaaa acactgtttt
    24541 gaggttgtag atagaactga cgaagtcagt aaccataccc atggcaaggc gacgttgacg
    24601 tggtttgaat tggattttcg aagagtataa gcattttact gaaattttat caggtagttt
    24661 aggatggcaa atgacattcc ctgtcaaaaa tggtaaaata agaaaaaata atctgagaat
    24721 cgaggaaaaa agatgcaaga aaagattttg gtaactggtg gtgccggttt tattggaacc
    24781 cacactgtta ttgaattgat ccaagcaggc catcaagttg ttgtggtgga taatcttgtc
    24841 aatagcaatc gtaagagttt agaagttgtt gaaagaatca caggagttga gattcctttc
    24901 tatgaggcag atattcgtga cacagttacc ctcagagata ttttcaagca ggaagaaccg
    24961 actggtgtca ttcactttgc tggtttgaag gctgttggcg aatcaacacg tatccctctt
    25021 gcctactatg acaacaatat cgctggaact gtcagccttt tgaaagccat ggaagaaaac
    25081 aactgtaaaa acatcatctt cagttcttct gcgacagttt acggggatcc gcacacagtg
    25141 cccatcttgg aagatttccc actttcagtg accaacccat acggtcgtac taagctcatg
    25201 ctagaggaaa ttttgactga tatttacaaa gcagactcag aatggaatgt tgtcttgctt
    25261 cgttacttta acccaatcgg agcccatgag agtggtgatt tgggagaaaa tccaaacggt
    25321 attccaaaca atctcttgcc atatgtgact caagtagccg ttggaaaatt agagcaagtg
    25381 caagtgtttg gagacgatta cgatacggaa gatggaacag gtgttcgtga ctatatccac
    25441 gttgtcgatt tggctaaggg tcacgttgca gctttgaaaa aaatccaaaa aggttcagga
    25501 ctaaacgttt ataaccttgg aactggtaaa ggttactcag ttcttgaaat tatccaaaac
    25561 atggaaaaag cggtgggacg tcctattcct taccgcatcg tagaacgtcg ctcaggtgat
    25621 atcgctgcct gctactcaga cccggcaaaa gctaaagcag aactcggttg ggaagcagaa
    25681 ctcgacatca cccaaatgtg tgaagacgca tggcgttggc aaagcaagca tccaaatgga
    25741 tttgaagact aagatgatga tttcaatcat cgtcccttgt ttaaacgaag aggaagtact
    25801 tcctcttttt tatcaggctc tggaagcttt acttccagat ttggaaacag aaatcgagta
    25861 tgtctttgtc gatgatggat caagtgatgg gaccttggaa ctcttaaagg cctatcggga
    25921 gcaaaatccg gcagtccatt atatttcttt ctctcgaaat tttggcaaag aagcagccct
    25981 ttatgcaggc ttgcaatatg cgacaggaga tttggtggtg gtgatggatg cagacctcca
    26041 agatcctcct agtatgttgt ttgagatgaa aaatgtacta gacaaaaatg tagacttgga
    26101 ctgcgttggg acacggagaa ctagtcggga gggagaaccc ttctttcgca gtttctgtgc
    26161 tgttctcttt tatcgcctca tgcaaaaaat cagcccagta gctctgccgt cgggtgtccg
    26221 tgactttcgt atgatgagaa ggtctgtggt cgatgccatt ttaagcttga ctgagtccaa
    26281 tcgtttttct aagggactct ttgcctgggt cggctttaaa acccactatc tggactatcc
    26341 aaatgtcgaa aggcaggctg gcaagaccag ttggagtttt aggcaactct ttttttactc
    26401 cattgaaggg attgttaatt tttcagattt ccctttgact atagcctttg tagctggtct
    26461 cctatcttgt tttctttctc tgctgatgac cttttttgtt gtggttcgga ccctcatttt
    26521 gggcaatccg acatctggtt ggacctctct gatggctgtt attctctttc ttggaggcat
    26581 tcaactcttg accattggga ttctcggtaa gtatatcagt aagatttatt tagagactaa
    26641 aaaaagacca ctttatctta tcaaagaaaa aagtgacctt cctgatttta cagaaaaaat
    26701 aaagtgaaaa gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg
    26761 ccattgattt aggcttcctg gtttccaatc agggcgcgag ttgggcaatt tttaacagcc
    26821 tctaagacat cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa
    26881 cgcacgattc cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagtccacag
    26941 gcgatacatc gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa
    27001 aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatttatg
    27061 atcaagaaga atcaagagca gggcgtcggc atcgaaacca cggaggggct gataggatgg
    27121 ctaatcgtat tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca
    27181 tcgttctcat ctatctatca tcggggggga gtaatcgcac agcagcctta aaagactttc
    27241 atgattctga tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga
    27301 gttcagagcc agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga
    27361 ttaaagttct cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg
    27421 ctcagttaga ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag
    27481 gtgatgttat aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg
    27541 tcctgcttcc agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac
    27601 ctaccttgat acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt
    27661 aggagttgaa gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg
    27721 acgttcagaa actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat
    27781 ccgtgaaaat gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga
    27841 gaaactggtt tctctccaac aagaaattgc ccagcaaggc gggattgtca tggatggtcg
    27901 cgatattgga actgttgtat tgccacaagc agaattgaaa attttcctag tagcttctgt
    27961 tgatgagaga gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagacct
    28021 tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc
    28081 tcctctcaaa caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga
    28141 agtagttgaa aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata
    28201 gattgatatc ggttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct
    28261 gttcgagaaa ttttgatttt caaagaatag tgaatgatga taaggagaaa tcatgaacaa
    28321 tttaccaaat tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt
    28381 ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct
    28441 tgtcgctatc gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa
    28501 ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat
    28561 ccgcatcgta gaaggcgatc acaatatcga ctgtaagatt gatggttttg gtgccatgaa
    28621 acttaaatca gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt
    28681 tatagccgta tcttcttgtt tctagcggct tttacgggag tttatcttga aattactagg
    28741 catggtggtt ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt
    28801 tttacccttt atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt
    28861 ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat
    28921 ttcctcttgg cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat
    28981 atcgttccca tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag
    29041 atttgggatc cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt
    29101 aatggcttgg ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc
    29161 tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt
    29221 gcctatatgg tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc
    29281 taatactctt cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact
    29341 gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    29401 tacaagggat tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt
    29461 tcttgcttat ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt
    29521 tcatgaaaca atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct
    29581 ccttttccat ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg
    29641 aacaaattga gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa
    29701 atggtttctt agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt
    29761 tatcattgag cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac
    29821 ggcttctctt tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg
    29881 aacgctacca aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg
    29941 ttggagcttc tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta
    30001 tctttctagc ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt
    30061 atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag
    30121 aaatgaaagg cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata
    30181 cagctattac catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt
    30241 tatctagttt tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt
    30301 ctttcttgat ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct
    30361 tggggcaaat tgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc
    30421 tggctggatt tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa
    30481 ttccagctaa actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag
    30541 cctttacgac cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg
    30601 tctttagtat cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc
    30661 agaagagagc ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga
    30721 gcatagttga ttgagtttgg aatagtacgc tgtagttgct aaaatatttc tagaaattaa
    30781 tttgactttt ctaatagagt tattcatatc ttatttcaat ctactataga aagctagccg
    30841 caggttgctc aaaatagtgt tttgaggttg cagatggaaa ctgacgtggt ttgaagagat
    30901 tttcgaagag tatgagattt ttatacccat acaatatttg ttttaggtcc ttgtttacag
    30961 actaatttct tgataaaata gaggttatga cgagatataa agcaactatt tcctatgatg
    31021 gttatgcctt tgctggcttt cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg
    31081 aaaaaacctt gaccagatta aataaagggc aaaccattac tgttcacggt gctggtagga
    31141 cagatagtgg ggttcatgcc ctgggacagg tcattcattt tgacctgcct tatcagatgg
    31201 atgaggagaa actccgtttt gccttggata cccagtctcc tgaagatatt gatgtgattt
    31261 cgattgagct tgtggcagat gattttcatt gccgttatgc caaacatagc aagacctatg
    31321 agtttattgt ggatagagga cgtcccaaaa atcctatgcg ccgtcactat gccacccact
    31381 ttccctaccc actcgatgtg gaacgaatgc agattgcaat caaaaagcta gagggaaccc
    31441 atgattttac cggttttaca gcctctggga ctagtgtaga ggataaggtt cgcaccatca
    31501 cagaagctag tttaatagtc gatgagacag gacaattttt gacctttacc ttttcaggaa
    31561 atggtttctt gtataaacag attcgcaata tggtggggac tcttctcaaa atcggtaaca
    31621 accgcatgcc agtagagcag attgatctca tcttggagaa gaaggacagg caacttgcag
    31681 gtcccactgc agcaccaaat ggtttgtatt taaaggagat tcgttatgaa gaataatcgt
    31741 attttagcac tttctggaaa tgatattttt agtggtggtg gactgtcagc tgatttggct
    31801 acctatacct tgaacggctt gcatgggttt gtagcagtga cttgtttgac agccttgaca
    31861 gaaaaaggat ttgaagtctt tccaactgat gataccattt ttcaacatga attagatagc
    31921 ttgcgtgatg tggaatttgg gggaattaag attggtcttc tccctactgt cagtgtggct
    31981 gagaaggcct tggactttat caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc
    32041 ttggtctgca aggaaacgca tgatgtagct gtcagtgagc tctgccaaga gttgattcgc
    32101 tttttccctt atgtcagtgt gattacgcct aatctcccag aagcagaatt attatccggt
    32161 caggaaatta aaaccttgga agacatgaaa actgcagcgc agaaattgca tgatttagga
    32221 gcgccagcag tcattatcaa gggaggcaat cgtcttagtc aggacaaggc tgtggatgtc
    32281 ttttatgatg gacagacctt tactatccta gaaaatccag ttatccaagg ccaaaatgct
    32341 ggtgcaggtt gtacctttgc ctctagcatt gccagtcact tgattaaagg tgataaactt
    32401 ttgccagcag tagaaagctc taaggctttc gtttatcgtg ctattgcaca agcagatcag
    32461 tatggagtaa gacaatatga agcaaacaaa aacaactaaa atcgcccttg tatccctatt
    32521 aaccgccctt tctgtggttc taggttattt cttaaaaatc ccaacaccta caggaattct
    32581 aactctttta gatgctggtg tcttctttgc ggccttttac tttggtagtc gtgaaggagc
    32641 ggtagtcgga ggactagcaa gtttcttgat tgacctctta tcaggctacc ctcagtggat
    32701 gttctttagc ttggtcaacc atggcttgca gggatttttc gcaggattta aaggaaaaag
    32761 tcagtggtta ggccttattt tagcaactat tgccatggta ggaggctacg ccttgggttc
    32821 tactttgatg aatggctggg cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa
    32881 tatggtaggg atgattgtag gatttattct tagtcaaagt atcaagaaga ttaagtaata
    32941 ctcttcgaaa atctcttcaa accacgtcag tttccatctg caacctcaaa acactgtttt
    33001 gagcagcctg cggctagctt tctagtctga ttttcattga gcataaagag gttgagtaaa
    33061 aagtctttca aataagaaaa acgcatagta tcaggtgttg aatgaacacc tgatactatg
    33121 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
    33181 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
    33241 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
    33301 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
    33361 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
    33421 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
    33481 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
    33541 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
    33601 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
    33661 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
    33721 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
    33781 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
    33841 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
    33901 aagaccatgg tatcaaagct catttcgtaa ccttcacgtt tcatggcaaa gtcaatttgt
    33961 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
    34021 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
    34081 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
    34141 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
    34201 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
    34261 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
    34321 ggttcctgat ctgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
    34381 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
    34441 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tatccctcta
    34501 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
    34561 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
    34621 ttttgacgtc actgtactct tcagcgattt cttggctgag gatatcctca taggcaggga
    34681 gttggatatc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
    34741 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
    34801 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
    34861 tttggtcatc agagaggaag gtacggcctt ggtgattttc aaatccatag taggtttcat
    34921 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
    34981 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
    35041 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
    35101 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
    35161 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
    35221 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
    35281 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
    35341 aggggtaatt gccatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
    35401 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
    35461 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
    35521 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
    35581 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gttcaaagtc
    35641 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
    35701 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
    35761 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
    35821 aaagacagca cggctcttgt caaatccctg tttgatgagt tgcaaatcgg cacctaggaa
    35881 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
    35941 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
    36001 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
    36061 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
    36121 cccttcggta ttgtagtgag ccagttgggc tggtcccttt tccaagtcaa aaccaaaata
    36181 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
    36241 agtagcagtt ggaactttcc gaatggcatc caatatcatg ttataggtag tatagatttc
    36301 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
    36361 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
    36421 agttttagaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
    36481 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
    36541 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggtt
    36601 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
    36661 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
    36721 gttcatgttt ctattatatc acaaaagtat atcacaaaag agggaaaaga cagatttggt
    36781 gtttcgtaga agtaaaaaca gcccaaagag ggctgtcagt taagatgaga tttcaactta
    36841 aatcgcaaac aagtcattca agttctcagc caaggttggg tgagtgaaga tttgttttgt
    36901 gaagtaagtg taaggaatct tgttgtccat agcaacagta ataatgttga tgatttcttg
    36961 agaaccttct gagaagatgc ttgcaccaag aatttctttt gtttctgtat taacaacagc
    37021 tttgaaagct ccgcgaaggt ctccatttac gtgaccacga ggcatggctg caacagggat
    37081 ttctttcact gcgtatggaa gtttcaaatc agctgcttgg ctttcagtca aaccaacttg
    37141 tgaaagtgca ggtgtgatga acatagtatt tggcacattg agacggtcct caagtgtgta
    37201 gctgccatct ccagcaaggt agctgtaaac aacacggaag tcatcaagtg aaatgtaagt
    37261 aaattgaaga ccaccgttga catctccaac tgcaaagaca ccaggaacgt ttgtttgaca
    37321 gtgtttatct actttaatag cgccacgttc agttagttca atatctgtat tttcaagttg
    37381 aagtggttct acatttggtt tgcgtccagt tgcgtagaga agggcgtcga aacggtaagt
    37441 ttcgtcttca gttacgacaa gcacttggtc accgtcgttt ttaatttcag tagtatggat
    37501 attttgaagc aattcaatac cgtcttcttc catgtattgt ttagcaagag ctgcgatgga
    37561 aggttctgca cgaggtagga atgtatccaa ggcatctagg actgtaacct tgcttcctag
    37621 tttattgtaa aggccagcaa attcaagacc gatatttccg ccaccaagga ctccaagttt
    37681 ttcaggcaat ttatccaagc tttggatacc tgttgagtca aagacgtttt tgcttgtagc
    37741 aagtccaggg attggcaaga cgtttgaaac agcaccagtg ttgatgacga tagtttcagc
    37801 agtcaattct tgtttttcat caccagcttg gatttcgatg actttatttg aaaggaagtg
    37861 agcttcagca tcaaagatat cgacgccagt accagcaaca gtcgtatagt ttttaccgtt
    37921 gaggcgacca gtgatcgtgt ttttggtagc aatgacttct tcaaaagaca agtctttctc
    37981 agcagcaacc agcaaagttt tagttgggat acaaccgatg ttgatacaag ttccaccgta
    38041 catagctttg ctacgttcaa cgagggcaac ttttttgcca gctgaagcca atttaccagc
    38101 tagtgtttta ccagctttac caaatccaat aacaattaaa tcgtatgtta acatttatct
    38161 tcctcctatt cgaattacat tctagcacaa gaaaaaaact tttgcacaat tctgctacga
    38221 aaaagacaga aaaatatgaa aacgatttcc aggcaaaaaa ctagtaattt tttgacaagc
    38281 ttgataaact aaaatcctat ctatttttat ataagataga ataaatgttc gaaaatagga
    38341 ggttttatga aatcgaatcg ttatattatt gcctttgctg gggtcatttt acacttaatg
    38401 ctgggttcga cttatgcctg gagtgtttat cgtaacccta ttattgaaaa aacgggatgg
    38461 gatcaggctt ctgttgcctt cgcctttagt ctagcaatct tttgtttggg cttatcggct
    38521 gcatttatgg ggcgtttggt agaaaaattt ggtccgagag tcatggggag tctatctgct
    38581 tttctatacg caggtggaaa tatcttaaca ggatttgcaa tagaccgtca ggaactgtgg
    38641 ttgttgtatc tagcttatgg cattttaggt gggcttggtt tgggagcagg ctatattacc
    38701 cctgtgtcaa cgattataaa atggtttcct gataaacgtg gtctcgcaac aggtttagcg
    38761 attatggggt ttggttttgc ttctttattg actagtccca tagcgcaaca tctcatcgca
    38821 ggggtagggc ttgtagaaac tttttatatt ttaggtgcaa gttactttat tatcatgctc
    38881 ctagcttcac aattcattaa gcgtccaaat gagcaagagc ttgcaatttt atctgcttca
    38941 gggaaagaaa aaacagactc tctgacgcaa gggatgactg caaatcaggc tctaaaaagc
    39001 aatcggtttt atatactttg gattattttc tttatcaaca tagcttgtgg tttaggctta
    39061 atttcagcgg catcgccaat ggcacaggag atggctggct tgtctacaag tcatgcagca
    39121 gtaatggtgg gcgttttagg gattttcaat ggatttggtc gcttgctctg ggcgagctta
    39181 tctgactata tcggtcgccc tctaaccttt agtatattac tgcttgttaa tcttttcttt
    39241 tctctctcac tttggctctt tacagattcc gttttatttg tagtcgctat gtctattttg
    39301 atgacttgct atggagctgg tttttcattg atcccagctt atctcagtga tatttttgga
    39361 accaaggaat tggccgctct gcatggttat attttaacag cttgggcaat ggctggttta
    39421 gcgggaccta ttttattagc agagacttat aaaatggctc attcgtatac acaaaccttg
    39481 ttcgtttttc tcattttata cagtatcgcc ttggctttgt cttattatct aggtcgttca
    39541 atcaaaaaag aaagtcaaaa accgcttaca tgattttctg tagaaatggg gctatctttt
    39601 gctctggtct tgtgttatac tagataggtt gcaaagaaaa cagtactttt cttttgtgga
    39661 aaagaagcaa cacgatttta tatctagtta tatgaaaata cgtcataaaa agaaaagtat
    39721 aaactaagcc ctatagggtg gcttcgcacc acctttagaa agaagaataa cgtgaaattt
    39781 aatgaattaa acttgtctgc tgatttgcta gcagaaattg aaaaagctgg ttttgtagaa
    39841 gctagtccta tccaagaaca aactattcct ttggcccttg aaggcaagga tgttatcggt
    39901 caagctcaga ctggtacagg aaaaactgca gcctttggct tgcctaccct tgaaaaaatc
    39961 cgtacagaag aagcgactat ccaagccttg gtcatcgctc caactcgtga actagctgtc
    40021 caaagtcaag aagaactctt ccgctttggt cgtagtaagg gagtcaaagt ccgttcagta
    40081 tatggcggat caagcattga aaaacaaatt aaggctctta aatctggtgc ccatatcgtg
    40141 gtgggaactc caggtcgcct cttggacttg attaaacgca aggccttgaa attacaagac
    40201 attgaatccc ttatcctcga cgaagcggat gaaatgctta acatgggctt ccttgaagac
    40261 atcgaagcca ttatttcccg tgtacctgag aaccgtcaaa ctttgctttt ctcagcaact
    40321 atgccagatg ccatcaaacg tatcggtgtt cagtttatga aagcccctga acatgtcaag
    40381 attgcggcta aggaattgac aacagaattg gttgaccagt actatatccg tgttaaggaa
    40441 caagaaaaat ttgacaccat gactcgtctc atggatgtgg cacaaccaga actcgctatt
    40501 gtatttggtc gtaccaaacg ccgtgtggat gaattgactc gtggtttgaa aattcgtggc
    40561 ttccgtgcag aaggaattca tggcgaccta gaccaaaaca aacgtcttcg tgtccttcgt
    40621 gactttaaaa atggcaatct tgatgttttg gttgcgacag acgttgcagc gcgtggtttg
    40681 gatatttcag gtgtgaccca tgtctacaac tacgatattc cacaagatcc tgagagttat
    40741 gttcaccgta tcggtcgtac aggtcgtgct ggtaagtcag gtcaatctat tacttttgtt
    40801 gctccaaacg aaatgggtta ccttcaaatc attgaaaact tgactaagaa acgcatgaaa
    40861 ggtctcaaac ctgcaagtgt agaagaatcc ttccaatcaa aaaaacaggt agctctcaag
    40921 aaaatcgaac gtgattttgc agatgaaacc attcgtgcca actttgagaa atttggtaag
    40981 gatgctcgca aattggctgc tgagtttact ccagaagaat tggcaatgta tatcttgagt
    41041 ctgacagtcc aagacccaga tagccttcca gaagtggaga ttgcacgtga aaaaccacta
    41101 ccgtttaaac catcaggtaa tggtttcggt ggtaaagcta agggaggtcg tggaggccgt
    41161 cgtggggacg accgtcgaga gcgtgatcgt cgtggcaatg gtcgccgtga tgagttcaaa
    41221 aaaggaagtc gtggcaacga tcgttttgat aaggaaaaac gttaccgtaa ggataataaa
    41281 aaaccacgca atactttaag cgaaaagcaa acaggctttg ttattcgtaa caaaggtgat
    41341 aaataagaaa aagcggttca aaatgaatcg cttttttata taaggagacc gaatgtgaaa
    41401 aagacaaata aaattattat attatctttt ataatattat gatacacaaa aataggcgac
    41461 ttgtcaatag aaaaggaaca atttaattaa aaatattctg gtttttaatt aaattgtaag
    41521 tcaatgcaag tcaataagga attttcagat aattattgaa aaagagacgt ttttatgtta
    41581 taatgatagc gattaaattc gaggtgaaaa atggcacatt tattagaaaa aactagaaaa
    41641 attacatcaa ttttgaaacg ctcagaggag cagttgcagg atgagctccc ttacaacgct
    41701 attacgcgtc agttagcgga tattattcat tgcaatgcct gcattatcaa tagtaaggga
    41761 cgtctgcttg gctattttat gcgttataaa acaaatacag atcgcgtaga gcaattcttc
    41821 caaactaaga ttttcccaga tgactacgtt caaggggcta atatgattta cgaaacagaa
    41881 gcaaacttgc ctgttgagca tgatatgagt attttccctg ttgagagtag agatgatttt
    41941 ccagatggct tgacgactat tgcaccgatt catgtatcgg ggattcgcct tggttctttg
    42001 attatttggc gtaatgataa aaaattcgaa gatgaggact tggttcttgt tgagattgcc
    42061 agtaccgttg ttgggattca gcttcttaac ttccaacgtg aagaagatga gaaaaatatt
    42121 cgtcgtcgta ctgctgtcac catggcggtc aatacccttt cttactccga actccgtgct
    42181 gtttcagcaa ttttagggga attaaatgga aatgaagggc agttgactgc gtcagtgatt
    42241 gcagatcgta tcggaatcac tcgctctgtg attgtcaatg ctcttcgtaa acttgagtct
    42301 gcggggatta ttgaaagtcg ctcacttgga atgaagggaa cctatcttaa ggtcttgatt
    42361 tcagatattt ttgaagaagt gaagaaaaga gattactaat gacaaaggct ttaatttcga
    42421 ttgattatac agaagatttt gttgctgata gtgggaagct gacagcaggt gctccagctc
    42481 aggcgatttc ggatgccatt agcaaggtaa ctcgattagc ttttgaacga ggagattata
    42541 tcttctttac tattgatgct catgaagaaa acgattgttt ccatccggaa agtaagttat
    42601 ttcctcctca taatctgatt gggacgagtg gacggaattt atatggagat ttggggatct
    42661 tttatcaaga gcatggttca gacagtcgtg tcttttggat ggataaacgc cattactcag
    42721 ctttttcagg gactgaccta gatattcgtt tgagagagcg tagagtgtct accgttatct
    42781 taacaggtgt cttgacggat atctgcgtcc tacatacagc tatagatgcc tataatctag
    42841 gatatgacat cgagattgtt aaaccagctg ttgcttccat ctggcctgaa aatcatcaat
    42901 ttgccctagg tcatttcaaa aatacactcg gagctaagtt agtagatgaa aatctaaatg
    42961 aactttctga gtaacctggt tggtgaaaat gaaaaaattt gaaaaaaagt gttgacaagc
    43021 atcccaaaag ttgatatact agtaaagtaa tcgacgcggg gatggcggaa ttggcagacg
    43081 cgcaggacta aggatcctgt gaccgcttta ggtcgtgagg gttcaagtcc ctctctccgc
    43141 ataggaaaag agctagctaa agctagctct tttgtatttc tctaaaaaat tagaatccag
    43201 tcaaatgtag tggagaatca gcgaaa
//
LOCUS       DAVLHB010000013        40627 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLHB010000013 DAVLHB010000000
VERSION     DAVLHB010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.013"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            146..883
                     /locus_tag="VXE36_000805"
     CDS             146..883
                     /locus_tag="VXE36_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0779147.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            880..2571
                     /locus_tag="VXE36_000806"
     CDS             880..2571
                     /locus_tag="VXE36_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0779148.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            2687..3250
                     /locus_tag="VXE36_000807"
     CDS             2687..3250
                     /locus_tag="VXE36_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0779149.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            3272..8935
                     /locus_tag="VXE36_000808"
     CDS             3272..8935
                     /locus_tag="VXE36_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0779150.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGKSYIKGEFKGKLLGTNDNVRHSIFDL
                     EYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYLEG
                     RDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADIEV
                     HRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPYGA
                     IDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRISEE
                     EANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTKFT
                     PYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGSQK
                     RYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTEST
                     YQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAVAA
                     LRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRLGS
                     SGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDYIQ
                     FEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSREK
                     RPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGSEW
                     VDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSEYG
                     ISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAFER
                     KNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFKKV
                     EPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFETSY
                     IAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRDEG
                     HAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEELQ
                     EGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            8996..10717
                     /gene="pabB"
                     /locus_tag="VXE36_000809"
     CDS             8996..10717
                     /gene="pabB"
                     /locus_tag="VXE36_000809"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0779151.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            10837..12363
                     /locus_tag="VXE36_000810"
     CDS             10837..12363
                     /locus_tag="VXE36_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0779152.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            12450..13369
                     /locus_tag="VXE36_000811"
                     /pseudo
     CDS             12450..13369
                     /locus_tag="VXE36_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            13504..14463
                     /locus_tag="VXE36_000812"
     CDS             13504..14463
                     /locus_tag="VXE36_000812"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0779153.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            14560..15399
                     /locus_tag="VXE36_000813"
     CDS             14560..15399
                     /locus_tag="VXE36_000813"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0779154.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(15447..15617)
                     /locus_tag="VXE36_000814"
     CDS             complement(15447..15617)
                     /locus_tag="VXE36_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0779155.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            15738..16622
                     /gene="miaA"
                     /locus_tag="VXE36_000815"
     CDS             15738..16622
                     /gene="miaA"
                     /locus_tag="VXE36_000815"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0779156.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            16615..17853
                     /gene="hflX"
                     /locus_tag="VXE36_000816"
     CDS             16615..17853
                     /gene="hflX"
                     /locus_tag="VXE36_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0779157.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQIKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            17846..18469
                     /locus_tag="VXE36_000817"
     CDS             17846..18469
                     /locus_tag="VXE36_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0779158.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAVFSGKRYFRSENRTAMLYID"
     gene            18484..19413
                     /locus_tag="VXE36_000818"
     CDS             18484..19413
                     /locus_tag="VXE36_000818"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0779159.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAGQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            19434..20189
                     /locus_tag="VXE36_000819"
     CDS             19434..20189
                     /locus_tag="VXE36_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0779160.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATVKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(20243..21151)
                     /locus_tag="VXE36_000820"
     CDS             complement(20243..21151)
                     /locus_tag="VXE36_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0779161.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            21215..21484
                     /locus_tag="VXE36_000821"
     CDS             21215..21484
                     /locus_tag="VXE36_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0779162.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            21484..21864
                     /locus_tag="VXE36_000822"
     CDS             21484..21864
                     /locus_tag="VXE36_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0779163.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAGLRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            21953..22180
                     /locus_tag="VXE36_000823"
     CDS             21953..22180
                     /locus_tag="VXE36_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779164.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(22220..22945)
                     /locus_tag="VXE36_000824"
     CDS             complement(22220..22945)
                     /locus_tag="VXE36_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEV0779165.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            23107..24948
                     /gene="typA"
                     /locus_tag="VXE36_000825"
     CDS             23107..24948
                     /gene="typA"
                     /locus_tag="VXE36_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0779166.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            24968..25222
                     /locus_tag="VXE36_000826"
     CDS             24968..25222
                     /locus_tag="VXE36_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0779167.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            25587..25886
                     /locus_tag="VXE36_000827"
                     /pseudo
     CDS             25587..25886
                     /locus_tag="VXE36_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            25969..27990
                     /locus_tag="VXE36_000828"
                     /pseudo
     CDS             25969..27990
                     /locus_tag="VXE36_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            27992..28633
                     /locus_tag="VXE36_000829"
     CDS             27992..28633
                     /locus_tag="VXE36_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779168.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            28737..30089
                     /locus_tag="VXE36_000830"
     CDS             28737..30089
                     /locus_tag="VXE36_000830"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0779169.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            30093..31151
                     /locus_tag="VXE36_000831"
     CDS             30093..31151
                     /locus_tag="VXE36_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0779170.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            31161..32327
                     /gene="divIB"
                     /locus_tag="VXE36_000832"
     CDS             31161..32327
                     /gene="divIB"
                     /locus_tag="VXE36_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0779171.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKATIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            32593..33294
                     /gene="pyrF"
                     /locus_tag="VXE36_000833"
     CDS             32593..33294
                     /gene="pyrF"
                     /locus_tag="VXE36_000833"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0779172.1"
                     /translation="MREHRPIIALDFPSFEVVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            33328..33960
                     /locus_tag="VXE36_000834"
     CDS             33328..33960
                     /locus_tag="VXE36_000834"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0779173.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQKNWQEG"
     gene            34140..34543
                     /locus_tag="VXE36_000835"
                     /pseudo
     CDS             34140..34543
                     /locus_tag="VXE36_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34639..35403
                     /locus_tag="VXE36_000836"
     CDS             34639..35403
                     /locus_tag="VXE36_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779174.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            35403..36155
                     /locus_tag="VXE36_000837"
     CDS             35403..36155
                     /locus_tag="VXE36_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779175.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            36165..36863
                     /locus_tag="VXE36_000838"
     CDS             36165..36863
                     /locus_tag="VXE36_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779176.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDFLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            36860..37507
                     /locus_tag="VXE36_000839"
     CDS             36860..37507
                     /locus_tag="VXE36_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779177.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(37594..38460)
                     /locus_tag="VXE36_000840"
     CDS             complement(37594..38460)
                     /locus_tag="VXE36_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779178.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(38472..39235)
                     /locus_tag="VXE36_000841"
                     /pseudo
     CDS             complement(38472..39235)
                     /locus_tag="VXE36_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(39236..39523)
                     /locus_tag="VXE36_000842"
     CDS             complement(39236..39523)
                     /locus_tag="VXE36_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0779179.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            complement(39533..39913)
                     /locus_tag="VXE36_000843"
     CDS             complement(39533..39913)
                     /locus_tag="VXE36_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0779180.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(39873..40541)
                     /locus_tag="VXE36_000844"
     CDS             complement(39873..40541)
                     /locus_tag="VXE36_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0779181.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFGNPST
                     LSRK"
BASE COUNT        12569 a         7141 c         8936 g        11981 t
ORIGIN      
        1 tacaacctca aagcggtact ttgagaaacc tgtggctatc ttcctagttt actttttcat
       61 ttttattgag tataagaggt ctttcctaag cagttagagg agaattttgc tatactgata
      121 ctagtaagtg gtaaaggagc agatcatgac ctacacaatc ttaatcgtag aagatgaata
      181 tctggtaaga caaggtttga ctaaactggt caatgtagca gcctacgata tggaaatcat
      241 cggtcaggct gaaaatggaa ggcaggcttg ggaattgatc caaaagcagg tgccagatat
      301 cattttaacc gatatcaaca tgcctcatct aaatggcatc cagttggcca gtctggtacg
      361 agaaacctat cctcaggttc atttggtctt tttaacaggt tacgatgatt ttgattatgc
      421 cttgtctgct gtcaaactag gtgtggacga ctacctgctc aaaccctttt ctcgtcagga
      481 tattgaggaa atgttgggga aaatcaaaca aaaactagac aaggaagaga aagaagagca
      541 gttacaagat ttattgacta ataggtttga aggaaacatg gcccagaaaa tccagtctca
      601 tctggctgat agccaattta gtttaaagtc tttagccagt gacttaggtt ttagtccgac
      661 ctatctgagt tccttgatta agaaagagtt gggcttgcct tttcaggatt atctggtgag
      721 agaacgtgtt aaacaagcta agctcttgct tttaactaca gatctgaaga tttatgagat
      781 cgcagagaag gttggttttg aagatatgaa ctattttacc caacgtttta agcagattgc
      841 aggtgtgaca cctcgtcagt ttaagaaggg agaagaccga tgaagcgttc ttctctttta
      901 gttagaatgg ttatttccat ctttctggtc tttctcattc tcctagctct ggttggaact
      961 ttctactatc aatcaagttc ttcagccatt gaggccacca ttgagggcaa cagccaaacg
     1021 accatcagcc agactagcca ctttattcag tcttatatca aaaaactaga aaccacctcg
     1081 actggtttga cccagcagac ggatgttctg gcctatgctg agaatcccag tcaagacaag
     1141 gtcgagggaa tccgagattt gtttttgacc atcttgaagt cagataagga cttgaaaact
     1201 gttgtgctgg tgaccaaatc tggtcaggtc atttctacag atgacagtgt gcagatgaaa
     1261 acttcctctg atatgatggc tgaggattgg taccaaaagg ccattcatca gggagctatg
     1321 cctgttttga ctccagctcg taaatcagat agtcagtggg tcatttctgt cactcaagaa
     1381 cttgttgatg caaagggagc caatcttggt gtgcttcgtt tggatatttc ttatgaaact
     1441 ctggaagcct atctcaatca actccagttg gggcagcagg gctttgcctt cattatcaat
     1501 gaaaaccatg aatttgtcta ccatcctcaa cacacagttt atagttcgtc tagcaaaatg
     1561 gaggctatga aaccctacat cgatacaggt cagggttata ctcctggtca caaatcctac
     1621 gtcagtcaag agaagattgc aggaactgat tggacggtgc ttggcgtgtc atcattggaa
     1681 aagttagacc aggttcggag tcagctcttg tggaccttgc ttggggccag tgtcacatct
     1741 cttcttgtct gtctctgctt agtgtggttc agtcttaaac gctggattgc tcctttgaag
     1801 gatttgagag aaaccatgtt ggaaattgct tctggtgctc aaaatcttcg tgccaaggaa
     1861 gttggtgcct atgaactgag agaagtaact cgccaattta atgctatgtt ggatcagatt
     1921 gatcagttga tggtagctat tcgtagccag gaagaaacga cccgtcagta ccaacttcaa
     1981 gccctttcga gccagattaa tccacatttc ctctataaca ctttggacac catcatctgg
     2041 atggctgaat ttcatgatag tcagcgagtg gtgcaggtga ccaagtcctt ggcaacctat
     2101 ttccgcttgg cgctcaatca aggcaaggac ttgatttgtc tctctgacga aatcaatcat
     2161 gtccgccagt atctctttat ccagaaacaa cgctatggag ataagctgga atacgaaatt
     2221 aatgaaaatg ttgcctttga taatttagtc ttacccaagc tggtcctaca accccttgta
     2281 gaaaatgctc tttaccatgg cattaaggaa aaggaaggtc agggccatat taaactttct
     2341 gtccagaaac aggattcggg attggtcatc cgtattgagg atgatggcgt tggcttccaa
     2401 gatgctggtg atagtagtca aagtcaactc aaacgtgggg gagttggtct tcaaaatgtc
     2461 gatcaacggc tcaaacttca ttttggagcc aattaccata tgaagattga ttctagaccc
     2521 caaaaaggga cgaaagttga aatatatata aatagaatag aaactagcta actcccagtc
     2581 aattctggga gttttatgcg taattgggca aactttctag gttgtctatc ttgctaaaaa
     2641 caagaaaaaa cggtatgata gaagagtgac aacagaggta acagagatga acgagacaca
     2701 gattcaaaga gaaacacgtc aggtagtgga agatgtttta gaaaagacca atttgaagca
     2761 gggggccctt tttgttttag gtctatcttc tagtgaggtg ctaggtggtc atattgggaa
     2821 agaatccagt caagagattg gtgagctgat agtggagact atcttggata ttctaggtag
     2881 tagaggtatc catttagcag ttcaaggttg tgagcatgtc aatcgggctc tcgttgttga
     2941 acgtcaggtg gcagagcagt ttggtctgga aattgtcagt gtccatccta ctcttcatgc
     3001 aggaggttcg gggcagttgg cagcctttaa gtttatgcag gatccagttg aggttgaatt
     3061 tatcaaggct catgctggat tggatatcgg agacactgca attggcatgc atgtcaagca
     3121 tgttcaggtt ccgattcgcc ctattttgag agagattggt catgcccatg taacggcact
     3181 ggctagtcgt ccaaaattaa tcggaggtgc gcgtgcgcac tatccgcaag atgctattag
     3241 aaagacctga gaatgaataa aggagataaa agtgtttaaa aaagaccgtt tttcaattcg
     3301 taagattaag ggagttgtag gctctgtatt tcttggaagc cttttgatgg ctccttctgt
     3361 agtggacgca gccacctatc actatgtaaa taaagagatt atttcacaag aagctaaaga
     3421 tttaattcag acaggaaagc ctgacaggaa tgaagttgta tatggtttgg tgtatcaaaa
     3481 agatcagttg cctcaaacag ggacagaagc atctgttttg acagcttttg gttatctatc
     3541 aggtgacatc ctcaaaacgc ttggcttgga cactgtttta gaagaaacct cagcaaaacc
     3601 tggagaggtg actgtagtcg aagttgagac tcctcaatca acaacaaatc aggagcaagc
     3661 taggacagaa aaccaagtag tagagacaga ggaagctcca aaagaagaag cacctaaaac
     3721 agaagaaagt ccaaaggaag aaccaaaatc ggagataaaa cctactgacg acacccttcc
     3781 taaagtagaa gaggggaaag aagattcagc agaaccagct ccagttgaag aagtaggtgg
     3841 agaagttgag tcaaaaccag aggaaaaagt agcagttaag ccagaaagtc aaccatcaga
     3901 caaaccaaca gaggaaccaa aagttgaaca agtaggtgaa ccagtcgagc caagtgaaga
     3961 cgaacaggca ccaacggcac cagttgagcc agaaaagcaa ccagaagctc ctgaagaaga
     4021 gaaggctgta gaggaaacac cgaaaccaga agataaaata aagggtattg gtactaaaga
     4081 accagttgat aaaagtgagt taaataatca aattgataaa gctagttcag tttctcctac
     4141 tgattattct acagcaagtt acaatgatct tggacctgtt ttagaaactg caaaaggtgt
     4201 ctatgcttca gagcctgtaa aacagcctga ggtaaatagt gagacaaata aacttaaaac
     4261 ggctattgac gctctaaacg ttgataaaac tgaattaaac aatacgattg cagatgcaaa
     4321 aacaaaggta aaagaacatt acagtgatag aagttggcaa aacctccaaa ctggggttac
     4381 agaagctgaa aaagttgcag ctaatacaga tgctaaacaa agtgaagtaa attctgagac
     4441 tgcaagtctt aaaacagcaa tttctagatt aaatacagat aaagttgaac tcgaaaatca
     4501 acttaagatt gcacagggaa aaactgaaac tgatttcagc atggaatctt ggactgtttt
     4561 gagtacagct aaaaataaag ctcaggaagt aaaagataac ggaacagcga cccaagaaca
     4621 aataaacgaa gcagagaaaa gtttgaaaac agcccttgct gacttatctg ttgacaaaac
     4681 agctttggga agcgctatcg atacagctac taagaaaaat aaagagaatt atacaaatca
     4741 aacatgggca gagttggaaa cagcgcttac agcagcaaaa tctgtaaata ctaacgagtc
     4801 taaacaaagc gacgttaacg aagctgctga aaaattaact gcaactatgg aaaaattggt
     4861 tgaattgtct gaaaagccac gtttgactct atctattgaa aagagagaca tagatcgaaa
     4921 agctacggtc acgtatactt tggaaaatcc agcaaatact caaataaaat caataactgc
     4981 aactctgaaa aaaggagagg aagttgttaa ggattttgtt ttaacagaag aaaatcttaa
     5041 aactaatcat ttaactgctt tgtttgaaaa gctagactac tacaaagaat acactctatc
     5101 tacggatatg gtatataaca gaggaaatga tgatgagacg gagagtattt cagaagaact
     5161 aattcagctg aatcttaaga aactagaatt gaaagatatc cagacagtct ctctgatgaa
     5221 atttgaaaat ggtcaagaaa gtcaggttac acacttgtct gataaaccga ccgatttgag
     5281 taaattatac ttaaaagtta catcatcaac gtctaaggat gctgtgttag ccgttagctc
     5341 tatagaagaa gagattattg aaaataaaaa aatctttaaa attcatgcag atacaccaga
     5401 attagtagtt cgtaagaaag atggcagtct ttctaaggga tttgactatt acatggagag
     5461 agttatccct catgatggtg atatttatta tgattttaaa gacttgattt cagctatgac
     5521 atctaatcct acaggtacgt ttattttagg gagagatatt tcctcgcgta atgtaaaacc
     5581 ggatggaaaa tcttatatca aaggtgaatt taaaggaaaa ctacttggta caaatgataa
     5641 tgttagacac tcgatctttg acttagaata tccattgttt gatactataa aatcaggagt
     5701 cgtgaaagat attgatttca agcatgtcaa tatggtattc ccagatagca atcaaggaga
     5761 taacgtagca acaattgcaa gagtaatcaa agataagaca aaaattgaga atgttaatgt
     5821 tgaaggttat ctcgagggtc gagatcatgt agctggttta gttaataatc ttgaaggtaa
     5881 ttccgaaatt gaaaatgtat cctttacagg aaagattaag tctaaaggtg gtaattctat
     5941 tacagcaggt attgcaggta gaaatatctt atctcgtgtt aaacgtgcct atgtaaatgc
     6001 agatatagag gtacatcgat catctaattc tagcatgctt gttgcagtaa atggaataaa
     6061 cgcagatgca agtggtggtt ggggaacctg gggtagactt actgagtcag ttgctaaagg
     6121 aacattagaa accaagcaag gagggcaagc tggaggagcc tcttctacag tctggcctta
     6181 tggagcaatt gataatgttg tcagctatgc aaaagtgacc aaagggaaag aattatttgg
     6241 atcagatggt gatttaaatt atgattggtt tatgaaaaaa attagtaata tttttggtgt
     6301 tcaaggcatc agctcaggcg attcgggtag tgattctaaa tttacgcgta tttctgagga
     6361 agaagcaaat caaaaagttg cttcttataa tattacagct cccaacttga tgagtgactc
     6421 aagtcttttg gtagacagac tcaatgaaag ttggaaaaat actgatcaat ttgaaagtat
     6481 acaggattat caagcccaaa accaattaat ttaccagaac ttgactaaat ttactcctta
     6541 ttacaataaa gaatttattg ttcatgaagg aaatgctctc actcctgaac aggaaatatt
     6601 gaagactaag aaaatcaaat cgattgtagg gttgaaagga acagagttcg ttgtagatgg
     6661 cagtgatatt gatactatca tgcttcattt tgaggatggt agtcagaagc gatataaggt
     6721 aacctctact ggtaagtttt cgataactaa tttaccggaa tatcaggttg aagatttaaa
     6781 tgtggtgtat acatcagaac atatagtaca tccactagat tcgtcactga taaataacct
     6841 tgttgaagaa ttgaaaaaag tagaattgta tacagagtct acttaccaag ttctaggtat
     6901 tgataaagat aatgctaaca aattgaatag aactaagaga ttattcttag atgagtcatt
     6961 agatgctgtt aaaacacaat tgcctacctt tgtaaaaaca atgtttgaaa atgagtggtt
     7021 gcacatcaat ggagaatcta gtggagctgt cgctgcttta cgacaaaaaa tcatggataa
     7081 taagacggct atattgcttg ctttgactta tatcaatcgt tattatgatg ttaaattctc
     7141 agactataat attaaaaaac tgatgctctt taaaccaact ttccatggtg aaaagattga
     7201 tctattagat cgattaatcc gactaggatc atctggagaa aatagattaa aaggttcaga
     7261 aaatgcagaa acgttcaagc agttatttgc tagcgaaacg aagcagaagg atttggtgac
     7321 ttatttagac tacaatcgct ctttgttgac taattatcaa acaacagggg aatggtttaa
     7381 agaaacgact aaggattata ttcaatttga ggaacgtcca tccttagtag aggagattaa
     7441 agatgccaaa tatcgagttt acgataattt aaccgcaccg tattatcaag gatatatcct
     7501 acctctctta acgttgaaga atactcattt agcaatttta tcgaactata gtactatgac
     7561 atttgtcagc cgtgaaaaac gccctaattg gaaaaatgaa gattttgata agtgggtgaa
     7621 atatgtagca actgctcata gaaaccatgt tgatacttgg tataagattt tacctgataa
     7681 tatcaaaggt aaaatggtta aagagaatgt tactgctgtt tgggaaggat tgagcatccc
     7741 aggaagtgaa tgggtagacc agaatgctgt agatagaaaa ggaagagatt acgccccagc
     7801 tcgagaattc tttaatcttg taggtggtcc tatgggaggt tggtatgctt accatggtta
     7861 tggtgcgcat gctggaggaa gaaatcgggt taattatgag gtgtttgatg tattaagtga
     7921 gtatggtata tcggtcttta ctcatgaatt gactcacgtt aatgatactt ggatttactt
     7981 aggagggtat ggtagacgtg aaaatatggg acctgaagct tatgctcagg gattattcca
     8041 gtctcctgtt ccaggtcagc cgggttgggg ggcgcttggt ctcaatatgg catttgaaag
     8101 aaaaaatgat ggtgatctaa tttataatgc ctccccaact caatttgaaa ataggaaaga
     8161 gttagatagt tatatgaaaa attataacga tactctcatg atggtggact acttggaagg
     8221 agatgcagtt atctctaaag gtaaagaagc tattactaaa tggtttaaaa aagttgaacc
     8281 taaggttgtt agtcaaacag ctcagtatga tacggttcgt cagttgactg ctgaagagaa
     8341 agaaaaactt tctgtttcta gtgttgatga tttagttgat caaggattaa tgtcagacag
     8401 agctgtagga aataatacct ataatccagc tgattttgaa acaagttata ttgcgataga
     8461 ttatatgact ggtatttatg gtggaggaaa gaatagtgta ggttcaccag gtgccttgat
     8521 gtttaaacat aatactttcc gtatgtgggg ctactatggt tttgaagaag gtgttctagg
     8581 atatgcttct aataaattta agcaagcatc tagagatgaa ggtcatgctg gacttagtga
     8641 taactttatt atttctaaga tttccaaagg ggaattttta actatggaag catttaaaaa
     8701 gggatatttt aagaaagtag tagaagagtt aaaaactaaa ggtattcgtc ctgttactat
     8761 caatcaaaaa acatatagca cctttgaaga attgcaagaa ggatttaagc aggctgttga
     8821 aagagatttg aagaaaaatc agttagatga gagggaaaca agaaacttca aattccaagt
     8881 tttcagacaa cttcttcaac aaacagatag ctttaaaact tctatcttta gataatcgaa
     8941 atctctcatc tgctttgcgg atgagggttt tcttatttta tgctatactt aaagtatgca
     9001 tagaaaaaca gtgattgatt ttaggacttt gggggagaga tataccttta cccagcctat
     9061 taaagagttg aaaacgagaa atgtagaaga agtggcagat ttgctggcac aagtggaaag
     9121 ctaccaagag caaggttatt atgtggtggg gtatgtcagc tacgaggctg cacctgcttt
     9181 tgaggaaaaa ttagcagttc acaaggatcc cctactggga gagtacctgc tttattttac
     9241 tgttcatgat agcgtagaaa cttcccctat tcctctgact tatgaggata ttgatttgcc
     9301 ctcaaattgg caggaagtaa cgtctgcagc agactatgaa aaggccattg cccaaattca
     9361 ccatcattta cggcagggag atacctatca ggtcaactac accgtccaac ttaagcaaaa
     9421 gttaaatgcc aatccttttg ccatctacaa tcgtatggtg gtagagcagg aggcgggcta
     9481 caatgcctat gtggaacatg acgagatggc agtgatttcc atgagcccag agctcttttt
     9541 tgagcaaaat gatcgcgagt tgacaacacg accaatgaag gggacgactc agcgtggggt
     9601 aactgaccaa gaagatcttg aacaggccag ttggttggaa caggatccca aaaatcgctc
     9661 tgaaaatatg atgattgtgg acctcttgcg caatgatatg aaccgtattt ctgaagttgg
     9721 gagcgagcac gtggagcgtc tgtgtcaggt agagcagtat tcaactgttt ggcagatgac
     9781 ttcgaccatc aagagtcagt tgcgagagga tgtggacctt gttgaaatct tccactcact
     9841 ctttccttgt ggttccataa cgggtgcacc gaaaattgcg acaatggaga ttatcaagga
     9901 cttggagcct caaccgcgtg gagtctactg tggaacgatt ggtctcttgc ttccaaatgg
     9961 acgacggatt tttaatgtgg ccattcgtac cattcaactt cacaaaggtc aagccattta
    10021 tggagttggc ggagggatta cttgggatag cacttgggaa tctgaatacc gtgaagttca
    10081 tcaaaaggca gcagttctct atcgtaaaca agctcgcttc caattaatta caactggaaa
    10141 aatcagccaa aaacaactga tgtttgaaga acaacatctg gaaaggctga gaaaagctag
    10201 tcggtatttt gcttatcctt ttgacccaga aattttgaga caaaagattg aagcagagtg
    10261 tcagacttgt gatgctaatc aagattaccg cttgcgaatt tctctcagca agtctggaga
    10321 gatagaattc agtcgtcaaa tcttaacacc tcttagtcca agtttttgtc aggccaaact
    10381 ttgtctgcaa gaagcgaatt tgaatcaatc ctttacctat tttaaaacga cttacagacc
    10441 gcatttgagc atagaggaac aagagaagat ttaccataat ggaaaaggag aacttcttga
    10501 aacctctatc ggaaatttgg ttctgaaaat cgatgggaaa ctctacacac cgcctatccg
    10561 acttggaatc ttgccaggaa tttatcacca gtatttacta gaaacaggac aggtagaaga
    10621 gaaagtcttg accttggcag attttgccca agcagaagct atttacggct gtaatgcagt
    10681 gagaggcttg tatgagttgc aagtgatagg attgtgagtt ttagctatta atagttttta
    10741 atatatatta aaatatattg gtgtttactt ttgatgagat atcatatttg tgttataatg
    10801 taaccgtaaa caatagaaat ttaaaggaga tttttgatga aatcaaaaat agttttggga
    10861 gcttcgctag cgatcgcaac acttagctta gtatctcttg tcgagattga aggactctca
    10921 ccgtttttaa tagagaatgt tagcgcaaat actcattctg caaataaagt tattaatcat
    10981 aaagtaagta tttacttaga aaatgctgat gaaggtaaag gtctaactgt aaacttttca
    11041 acagacagtg ttagtccaaa tttatttgat gagttcgaaa aaaagagtgg aattacaata
    11101 actactatgt tagtgaatgc taagacaggt gaagttgtag aaaaaagatt aacaccaagc
    11161 gtttttttac gttccaatga tttaaccagt gggaccatat cttcgtttat ttttagtgaa
    11221 tatcctgatg gagaatataa atatgttgtg tctaaaggag actttatcga tcctaagact
    11281 cagtttaaac atcagtatag aggagaatct ccagttttta gaatacgtaa tcgaaaatat
    11341 gtggagttgg gaacaactga taaaaaatta gatgaaagac gtgataatag cgtttataaa
    11401 gatggggttg ttgaacacaa ggtaaattta agtttaacaa gttatcaagg aggtaatgga
    11461 gttactgcaa ttttttcaac tgatagtgtt aactctaact tacttaattc ttttggtgaa
    11521 aaggctaaaa aagttttgat taggtctaag ttaattaatg ttaagactgg cgaggttatt
    11581 gatgaaacgt tttctccaaa agtaagttta acctctaaaa ttttgaaaag tggttctaca
    11641 gcagtatttt attttataga tttaactgat ggcgaatata aatatgttgc gtatgaaagc
    11701 cagcaatata ctgatcctca aacaacattg actcatcagt atagaggaga atctcctatt
    11761 tttagtatca aagatggaaa attttctggt ttagtatctg cctcaaaacc agacgaaaac
    11821 ccgaagccaa cgccaaaacc ggatgagaaa ccaaaacctt cagcaccaca acaggagaaa
    11881 acaaaaccta cagttcagtc tggttgggta ggttcatctt attatcaaaa tggtaaaaaa
    11941 gtcactagta agtggatttt tgataaaaaa tataattcat acttctatct agatgcatca
    12001 ggaaattatg ttcaaaacgc ttgggtaggt aactattatc tcaaatcagg cggatacatg
    12061 gctaaaagtg agtggattta tgataagaac tatggttcat actactatct aacatcagaa
    12121 ggcagctacg ctcgtaacac ttggtcaggc aattattatt tgaagtcaaa tggtaagatg
    12181 gctaaaagtg agtgggtata cgatagtaac tacaaatcat attactactt gacatcagaa
    12241 ggaagttatg ctcgtaacac ttgggtaggc aattactatc ttaaatcaaa cggtaaaatg
    12301 gctgttaatg aacgtacacc agatggttat cgtgtagatg gttcaggtaa atgggttaaa
    12361 taagaaacta aaaaatagga taataggtaa tatcagatga ataaaaaaaa ttattttcat
    12421 gtgctttagc attttcaacg attggaacat tgtcaacgat tgataaatca ggagttcttc
    12481 ctttttcagc gcaaacggtg caggctgaca tacaaacgct taccccaatg gcaaaatatt
    12541 atattattct tccgaaggat gcagaaatat ataaaacttg gagaggtact gtcaatattc
    12601 ccattattga tgctacaaaa actactccag aattatctta tttcaaagaa gatcatcgca
    12661 actatatagc taatgagaat aagtctggtg ccaattacat agagtggaag ggaacagtag
    12721 aagagtttaa agaggccatt aagaagttga ctgataaaaa atcaactact gcaacaccaa
    12781 aaaaggatga aaagccaaca ccaaaaccgg atgagaagcc aaaaccaaca cctacagttc
    12841 agtctggttg ggtaggttca tcctattatc aagatggtaa aaaagtcatt agtaagtgga
    12901 tttttgataa aaaatataat tcatacttct atctagatgc atcaggaaat tatgttcaaa
    12961 acgcttgggt aggtaactat tatcttaaat caggcggata catggctaaa ggtgaatggg
    13021 tttatgatgc cacctatcaa gcttggtatt atttgacatc agatggttct tatgcttaca
    13081 gtacatggca aggaaattac tatctaaaat cggatggtaa aatggctgtc aatgaatggg
    13141 ttgatggtgg acgttattat gttggcgctg acggagtttg gaaggaaggt caagcaagta
    13201 cagcttcttc tagtaatgat agcaatagtg aatattctgc tgctttagga aaggcaaaaa
    13261 gttataattc gttattccac atgtcaaaaa aaaacgtatg tatagacaat taacttctga
    13321 ttttgataaa ttttcaaatg atgcagctca atatgccatt gatcattaaa tgattaacag
    13381 atactggtag gcgaaaaaat tccttataat tcatttacgc aaacctttgc ataagtgaat
    13441 ggattttgat atactagtac tgtaagcatt ttcaattact acacaatgaa aaaggagaat
    13501 atgatgagtc aaaagattat tgggattgac cttggtggaa cttctatcaa atttgcaatc
    13561 ttaacaacag caggagaaat ccaaggaaaa tggtcaatca agaccaacat tttggatgag
    13621 ggaagtcata tcgttgatga tatgattgag tctattcaac atcgtttgga cttgcttgga
    13681 ttggcagcag cggacttcca aggcattgga atgggatcac caggtgtggt tgaccgtgac
    13741 aaagggactg ttatcggtgc ctacaacttg aactggaaaa cccttcaacc aatcaaacaa
    13801 aagattgaaa aagctttggg cattccattt ttcatcgata atgatgccaa cgtagcagct
    13861 cttggtgagc gctggatggg tgctggagat aaccaaccag acgttgtctt tatgacactc
    13921 ggtactggtg ttggtggcgg tatcgtcgca gaaggcaaat tgcttcacgg tgttgctggt
    13981 gcagcaggtg agcttggtca catcactgtt gactttgacc agccaatctc atgtacttgc
    14041 ggtaagaaag gctgccttga gacagttgct tcagcaacag ggattgtcaa cttgactcgt
    14101 cgctatgccg atgaatacga aggcgatgca gccttgaaac gcttgattga taatggagaa
    14161 gaagtaactg ctaagactgt ctttgatctc gcaaaagaag gagacgacct tgctttgatt
    14221 gtttaccgta acttctcacg ttacttggga atcgcttgtg ctaacattgg ttcaatccta
    14281 aacccatcaa caatcgtcat cggtggtggt gtgtcagctg cgggagaatt ccttctacaa
    14341 ggtgttcaaa aagtttacga tgaaaatagt ttcccacaag tacgcacatc tactaaatta
    14401 gctcttgcaa ctctaggaaa tgacgctgga gttatcggag cagcatcact tgtattgcaa
    14461 taagataatg agagaggaaa atgctaacct agagttagta atgttcctct tttatttttt
    14521 atgctatact agttaggaca atgaatgagg tgagagtaaa tgacaaaagc agatacgatt
    14581 tttaaagaga atattgaacg cattctaaag gaaggtgttt tctcagagca ggctcgtcct
    14641 aagtacaagg atgggactgt tgctaattcc aagtatgtaa ctggtgcctt ttccgagtac
    14701 gacttatcta aaggagaatt tcctatcaca accttgcgtc ccattgcaat caaatccgcc
    14761 atcaaagaag ttctctggat ttaccaagac cagtcaaata gcttagaagt gcttaatgac
    14821 aagtacaatg ttcactactg gaatgactgg gaagttggag acacgggaac cattggtgag
    14881 cgctatggtg ccgttgttaa gaaacacgac attatcaata agcttctcaa acagttggaa
    14941 accaatcctt ggaaccgccg caatattatt tcgctctggg attaccaagc tttcgaagaa
    15001 acagatgggc tgctcccgtg cgcctttcag accatgtttg atgttcggcg tgttgatggg
    15061 gaaatctatc tggatgcgac cttgacccag cgctccaatg atatgctggt ggcccaccac
    15121 atcaacgcta tgcagtatgt ggctttgcag atgatgattg ccaaacattt tggctggaag
    15181 gttgggaagt tcttctactt catcaacaac ctccatatct atgataatca atttgaacaa
    15241 gctcaggaat tgctccgtcg ggagccgtca aactgccaac cacgcttggt tttaaatgtt
    15301 cctgatggga ctaatttctt tgatatcaaa gcagaagatt ttgagttggt ggattatgac
    15361 cctgttaagc cacagttgaa gtttgaccta gctatttaaa agaatagaaa aaagaagttg
    15421 agaataatcc caacttcttt tgtttcttaa cgtgatacgc ggcgacgagc tgctttttta
    15481 cggttttctt cgatgaaagc tgctttttgc tcttctggtt cgattacttt ctttttaaat
    15541 gcgtatactg cacctgcaac ggcagcgaca gttcctgcga cacctgttac aagaccttta
    15601 gcgaatcctt tagccatgag tcttcctcct ttatattctc aatcagccag cctcctcaag
    15661 aggtcacatt tttctgactg acctttttgt gttataataa tagtaacgaa aaaatgggaa
    15721 tttttcaagg aaaaaagatg aaaacaaaaa taattgtgat tgttggaccg actgctgttg
    15781 gaaagacggc tctagctatt gaagttgcaa agcgctttaa tggcgaagtg gttagtggag
    15841 atagccagca agtctatcga ggacttgata ttgggacggc caaggctagt ccagaagagc
    15901 aggcagctgt tcctcatcat ttaatcgatg ttagagagat aaccgagtct tactcggctt
    15961 ttgattttgt ttcagaagct aagatgacta ttgaggatat tcacagccgt ggcaagctag
    16021 ccattatcgc cggtgggact ggactttata tccagagctt gctagaaggt taccacctag
    16081 gtggggagac tcctcatgag gagattttag cttatcgagc tagtttggag ccatattcag
    16141 atgaggaatt agcccatttg gtggagcaag caggccttga gattccccag tttaatcgtc
    16201 gtcgtgctat gcgtgcctta gaaattgccc attttggtca ggatttggaa aatcaagaga
    16261 ttttgtatga accgctgatt atctgcttgg atgatgaacg tagtcaactt tatgagcgta
    16321 tcaaccaccg agtggatttg atgtttgagg ctgggctttt ggatgaggcc aagtggctgt
    16381 ttgaccattc ccctaatgta caggctgcta aaggaattgg ctataaggaa ctctttcctt
    16441 atttccgtgg agagcagacc ttggaggaag ctagtgagag tcttaaacag gcgacccgtc
    16501 gttttgccaa gcgtcagctg acctggttcc gtaatcgcat gcaggtcacc ttttatcaga
    16561 ttggagaatc tggtgtacaa gaccgcattt taagccagat agaggagttt ttagatgatt
    16621 gaaacggaga aaaaagagga gcgagtcctg ctgattggtg tggaattgca gggtatggac
    16681 agttttgacc tctccatgga agaattggct agtttagcga aaacggcagg ggcagtcgtt
    16741 gtagatagct acagacaaaa acgtgaaaaa tatgattcca agaccttcgt cggctctggt
    16801 aagttggaag agattgcgct tatggtggat gcagaagaaa tcactactgt catcgtcaac
    16861 aaccgtctga ccccaaggca gaatgtcaat ctagaggaag ttctcggtgt taaggtcatt
    16921 gaccgtatgc agttgatttt ggatatcttt gccatgcggg ctcgaagcca tgaagggaag
    16981 ctccaagtcc acctagccca actcaaatac ctcttgcctc gcttggttgg tcaggggatt
    17041 atgctcagcc gtcaggcagg gggaattggt tcccgtggtc ctggtgaaag ccaactggag
    17101 ctgaaccgtc gtagcgttcg caatcaaatc acggatatcg agcgccagat caaggtggtt
    17161 gagaaaaatc gtgcgactgt cagagaaaaa cgtttggagt ctagcacttt taagattggt
    17221 ttgattggtt atactaatgc tgggaaatca actatcatga acatcttgac cagtaagacc
    17281 cagtatgaag cagatgagct ctttgcgact ctggatgcga caaccaagag tattcatctg
    17341 ggaggcaatc tccaagtaac tttgacagat accgttggct ttatccaaga tttgccgaca
    17401 gagttggtgt ccagtttcaa gtcaaccttg gaagaaagca agcatgtgga ccttctggtt
    17461 catgttatcg atgctagcaa tccttaccac gaggaacatg aaaaaacggt tctctccatc
    17521 atgaaagacc tggacatgga agatattcct cacttgacgc tttataataa agcggatttg
    17581 gtggaggatt tcacgcctac ccaaacgcca tataccctca tttctgccaa gtctgaggac
    17641 agtcgtgaaa acttgcaagc attattgcta gataagatta aggaaatttt tgaagcattt
    17701 accctgcgag tgcctttttc aaagtcctac aagattcatg atttagagag tgttgcaatt
    17761 ctggaagaac gtgattatca ggaagacggc gaagtgatta caggctacat ttccgagaaa
    17821 aataaatgga ggttagaaga attttatgac tgatattaaa actttggctc taaagtatgg
    17881 aggttataca agtctggaca aggtctatct ggatcagctt ctagctggta aaacagagca
    17941 ggagcagtta acacttatta cacctccgcc aagtgttgtt aatgcctact ttgcagaact
    18001 ctatcagaaa aaaagtcctc aggctgcgac ggattatttt gcagaactca gtcaggaact
    18061 gaatctttac aatactgagc caagtttcac cctagaaaat aagtctttta ttcggcttaa
    18121 tctgtctggt aaatcctttg gtttttgtta tgagagtgac ggctttggtc ggattttctc
    18181 tgaaaatgag gagaaaatct cggatgactt gctctttgaa attgcgcaaa ttttccccca
    18241 tcaattagtc tttgaagagt ctggtaagat ttacatgaag cctgtcgagg acgaggaagt
    18301 tgtcagccta gaaagtctca cagctttgac tgatttggaa agattggctg atggtcgaaa
    18361 acgtctcaaa ggctacagcc aagaggattt attgcaagaa gctgctgttt tttctggcaa
    18421 acgctatttc cgatcggaaa accgcacagc catgttatat attgattaat tagaaagtat
    18481 cgaatggata ttcaattttt aggaacgggg gctggtcagc cctctaaagc tcgcaacgtt
    18541 tcaagtctcg ccctgaaact tttggacgag attaacgaag tttggctctt tgactgtgga
    18601 gaaggtacgc aaaatcgcat tctggaaacc acaattcgac cacgtaaggt cagcaaaatc
    18661 tttattaccc atctgcatgg agaccacatt tttggtttgc caggtttcct ttctagccgt
    18721 gcctttcagg ccaatgaaga gcagacagat ttggaaatct acggacctca aggaatcaag
    18781 tcatttgtct taaccagcct tcgtgtgtca ggttctcgtc tgccctaccg cattcatttc
    18841 catgagtttg accaagattc tctgggtaaa attcttgaaa ccgataaatt cactgtgtat
    18901 gcagaggagc tggaccacac tattttctgt gttggctatc gtgtcatgca aaaggatcta
    18961 gaagggacgc tggatgctga aaaactcaag gctgctggtg ttccgttcgg cccgcttttt
    19021 ggtaaaatca aaaacggcca ggatcttgtt ttggaagacg gaactgaaat caaggcagca
    19081 gactatatct cagcgccacg tccaggtaag attatcacta ttttaggaga cactcgaaaa
    19141 acggatgcca gtgtgcgtct ggctgtcaat gcagatgtcc tagttcatga gtccacttat
    19201 ggcaagggtg atgaaaaaat tgctcgtaac catggtcact caactaatat gcaagctgga
    19261 caagtagcgg tagaagcagg tgccaaacgc ctcctactca accatatcag tgcccgcttc
    19321 ctctcaaaag atataagcaa actcaagaag gacgctgcca caatttttga aaatgtccat
    19381 gtggtcaaag acttggaaga agtggaaatc tagcagtcac agaaaggata agtatgccta
    19441 ctattctcat taccggagct agcggtggtc tagctcaaga aatggtcaaa ctcctgccca
    19501 atgaccaact catcttgctt ggtagaaata aggaaaaatt agcccaactc tacggaaatt
    19561 attcccatgc agaattgatt gaaattgata ttaccgacga ttcagcccta gaagctctgg
    19621 taactgatct ttatctccgc tatggcaaga ttgatgtctt gattaacaac gctggttacg
    19681 ggatttttga gggatttgac cagattgctg ataaagatat tcaccagatg tttgaggtca
    19741 atacctttgc cctgatgaat ctgtctcgtc accttgcggc tcgtatgaag gaaagcagca
    19801 aagggcatat catcaacatc gtcagcatgg caggtttaat agctactgtc aagtctagtc
    19861 tttactcagc gaccaagttt gcggctattg gtttttcaaa tgctctgcga ctcgaactta
    19921 tgccctatgg agtctatgtg acaacagtca atccaggtcc aatccgaaca ggattttttg
    19981 accaagctga cccagatgga acttatctta aatcggttga ccgcttcctc ttagaggcag
    20041 atgcagtggc taaaaagatt gtcaagatta taggcaaaaa taaacgagaa ctcaatctcc
    20101 cgattttgtt gaacctagcc cataagtttt atactctctt tcccaagcta gctgataagt
    20161 tggcagggga aacttttaat tataagtaaa aagaaccaat gtgcaggttg ttgctagcct
    20221 acatattggt tcttatcatt tctcaactat caaactgaac ttcttctagg agatagtcta
    20281 taaagcgttc gcccatctta gataggctgg ttttctcatg ctggatatag accagctcga
    20341 tcgggtcatc aatatccagt gggatagaaa cgatattgtc tccgtttagg ttgctgttca
    20401 aaatccctgt cgcaatggta taaccatcca aaccaatcaa gagattaaag agggtggcac
    20461 ggtcactgac cacaatggat ttcttgtggt gttcttgaga aagaatctct tctgaaaagt
    20521 agaaggagtt gtgcgtccct tggtcatagc tgaggtaagg gaaattctcc aaatcagaca
    20581 gtttcacctt gtctttcttt gccagagggt tggtcttgct gacaaagata tgcggttgcg
    20641 ctgtgaagag atggtgggct agcaggtgat tgtcatccag catcttggtt aaaacatcac
    20701 ggttgtagct gttcaaaaat aggacaccga cctcactacg gaaattcttg acgtcgtcaa
    20761 taatctccca agtccgagtt tcacgaagga agagttcgta tttctccata tcgcttttct
    20821 tgagcaaaga gacaaaggca ttgaccacaa aggcatagtg ttgagacgaa acgctaaaga
    20881 gttcgcggtg ggcgacagga tttttatagc gttcctccag aagctgggtc tgctcgacaa
    20941 cctgacgggc ataagagaga aactccatcc catcacgggt caaggtgatt cccttgggat
    21001 tgcggataaa gatctcaatg cccatttcat tttccaaatc tcgcactgca ttggagagac
    21061 ttggctgagt gataaagagt tgcttggctg cctcattcat ggagccagtt tcgacgattt
    21121 tgataatata atgtaattgt tgaattctca tgtttttatt gtaccatact tgccttagaa
    21181 tcgctaaaga agataggaaa ataaggagca ttgtgtgagt ctcttcttga aaaaaacaca
    21241 aaattttgct agaatgagtc ttatgaaaac attctatgat gtgcagcaat tcctcaaacg
    21301 atttggtatt attgtttaca tgggaaaacg cttatatgat attgaactga tgaagttgga
    21361 actatctcgg atttacgatg cagggttgat ggataaatta gactatctag aggcagaagc
    21421 agttcttcgc agagagcaca aggtagaatt ggattatatt gagaaaaatg gagaaaagaa
    21481 ctaatggtta cttggatttt gtgggcactt atactagcaa tgttggcgtg gatgggcttt
    21541 aactatcttc gtattcgccg tgcggctaaa attgtggaca atgaggagtt tgaagccttg
    21601 attcgtacgg gtcaattgat tgatttgcgc gacccagcag aattccacag aaaacatatc
    21661 cttggtgcac gcaatattcc ttcaagtcag ttgaaaacta gtcttgcagg ccttcgtaaa
    21721 gataaacctg tccttctcta cgagaaccaa cgtgcgcaac gagttacaaa tgcagctctt
    21781 tacttgaaaa aacaaggttt ttctgagatt tatatccttt cttatggctt ggattcttgg
    21841 aaagggaaag tgaagactag ctaaccttat ttccaaatta gtcgaatgat aggatgaagc
    21901 tattgtttta tagtataatt aatttgtata aaatttaaag agttcttaga acataaaaga
    21961 aaagaagaaa aatccacttt ttgtgggtat cttgtcgatt attcttggtt tgttatttcc
    22021 aattgtaggc ctgattttgg gtatcatagg attggtcttg gctatttcat accaaaaaga
    22081 gtcacaatta gactataaaa tagaaaagat tcttaatatc ttaggaattg tgatttctgt
    22141 agttaactgg attgtagcaa tcgccttaat ttttcgataa ataaaagaaa aaagctttag
    22201 ttttaaagct ttttttgttt tatcgactca tctctaaata gtttttaatg atttgtaact
    22261 ctttttggtt caaagggcgg tagttacctt ctgctaaatc tgggttcaat gtgaagtccc
    22321 caaattggat tctcttgagg ctagtcacct taacaccaac cgagaggaac attttcttga
    22381 tttgatgaaa ttttccttct gaaatggtga tagaggcttg actgagggag ggacttgcag
    22441 atagaatctc tagttttgcg ggtttacaga cagtaccatc taaaaagaca attccctttt
    22501 gaaaggcttg gatatggtca ggtgttagaa gtccattaac ctcaacttga taagtcttat
    22561 cgacatgata ttggggatgg aggagttgga agcccaaggg accgttatcg gtcaagagaa
    22621 ggagtcctgt tgtatctcgg tccagtcggc cgacggcata gagcttgtca gactggatgt
    22681 cagatggaag caggtccatg acggtcggaa gttccttgtc tttgttggct gtaacgacac
    22741 cagcaggttt atgaagcata agataggtgt gttcatagcc ttgaatgatt cgatcctgaa
    22801 aaaggagttc ttgtagtcct gtatcgatat tttgggctag ggagcgggct gggcaactat
    22861 cgacgagaat gtcccctttg agtaaggctt gtttcatggc ctttcggctg attttttctt
    22921 gagctaataa attatctaaa cgcatactgt gcctatctta tcataagtcg cttgctttga
    22981 aaaggcttga cgtgaaaaga aaagcggagt gaaaacattt acacttgctt gagttatgtt
    23041 atttatttga aattatggta taatcgttca gttagaaaat aaattttgaa tattatagag
    23101 gaaatcatga caaaattaag agaagatatc cgtaacattg cgattatcgc ccacgttgac
    23161 cacggtaaaa caaccctggt tgacgaatta ttgaaacaat cagaaacgct tgatgcacgt
    23221 actgaattgg cagagcgtgc tatggactca aacgatatcg aaaaagagcg tgggattacc
    23281 atccttgcta aaaatactgc cgttgcttac aacggaactc gtatcaacat tatggacaca
    23341 ccaggacatg cggacttcgg tggagaagtt gagcgtatca tgaaaatggt tgacggtgtt
    23401 gtcttggtcg tagatgccta tgaaggaacc atgccacaaa ctcgtttcgt attgaaaaaa
    23461 gccttggaac aagaccttgt cccaatcgtg gttgttaaca aaatcgataa gccatcagct
    23521 cgtccagcag aagtagtgga tgaagtcttg gaacttttca tcgagcttgg tgcagatgac
    23581 gaccagcttg atttcccagt ggtttatgct tcagcgatca acggaacttc ttcattgtca
    23641 gatgatccag ctgaccaaga agcgactatg gcaccaatct ttgacacgat tatcgaccat
    23701 atcccagctc cagtagataa ctcagatgag cctttgcagt tccaagtgtc acttttggac
    23761 tacaatgact tcgttggacg tatcggtatc ggtcgtgtct tccgtggtac agttaaggtt
    23821 ggggaccaag ttaccctttc taaacttgac ggtacaacta aaaacttccg tgttacaaaa
    23881 ctcttcggtt tctttggttt ggaacgtcgt gaaatccaag aagccaaagc gggtgacttg
    23941 attgccgttt caggtatgga agacatcttt gtcggtgaaa ccatcactcc gacagatgca
    24001 gtagaagctc ttccaatcct acacatcgat gagccaactc ttcaaatgac tttcttggtc
    24061 aacaactcac catttgctgg taaagaaggt aaatgggtaa cttctcgtaa ggtggaagaa
    24121 cgcttgcagg cagaattgca aacagacgtt tcccttcgtg ttgacccaac tgattcacca
    24181 gataaatgga ctgtttcagg acgtggagaa ttgcacttgt caatccttat cgaaacaatg
    24241 cgtcgtgagg gctatgaact tcaagtatct cgtccagaag ttatcgtaaa agaaatcgac
    24301 ggtgttaaat gtgaaccatt tgaacgtgta caaatcgaca ctccagaaga ataccaaggg
    24361 tctgttatcc aaagcctttc tgaacgtaaa ggtgaaatgt tggatatgat ttcaactggt
    24421 aatggtcaaa ctcgtttggt cttccttgtt ccagcgcgtg gtttgattgg atactcaact
    24481 gagttcttgt caatgactcg tggttacggt atcatgaacc ataccttcga ccaatacttg
    24541 ccattgattc caggggaaat tggtggacgt caccgtggtg cccttgtttc tatcgatgct
    24601 ggtaaggcta caacttactc aatcatgtct atcgaagaac gtggtacgat ctttgtcaac
    24661 ccaggtactg aggtttatga aggaatgatc atcggtgaaa actctcgtga aaatgacttg
    24721 acagttaaca tcacgaaggc aaaacaaatg accaacgttc gttcagctac taaggaccaa
    24781 acagctgtta tcaagacgcc tcgtatcttg acacttgaag agtctcttga gttcttgaac
    24841 gacgatgagt acatggaagt aacgcctgag tctatccgtt tgcgtaaaca aatccttaac
    24901 aaagcagagc gtgagaaagc taacaagaag aaaaaatcag ctgaataaga gctagaaaga
    24961 gagaaagatg gtctatttag tcctaggaat tttactgctc ctactctatg tatttgcgac
    25021 accagaaagc attaaaggga cagtcaatat cgtcgctatg gtatgtattt tagtggcact
    25081 cttgatttta ttggttctat cttttctgaa aatttttcaa ttaccaacag aaatattcct
    25141 agcaatagcc atgttgctcc tagcttactt tagtgttaga gacattacac tcatgccagt
    25201 caaaaaaagt aaaagaagat aaaaaagaga gttttggctc tcttttttgc taggaatttt
    25261 acaagattgc aatttatttt tgagttatca ccatctcttt tgtttggata atatgaatgg
    25321 gaaaaacttg aataaaattc gttaatggca tctattttat atttggttag tactggttgc
    25381 atattatttt gaaataaaac tactatataa tattattcat agaggtaata tagtaaaata
    25441 tctaaaaaat tcgatttttt ccttgacaac aaataataaa aatgttattc ttatcacata
    25501 agaaagcggt ttcaataaaa gagagaggag gatttatttt gttgcattgt tgctcaaggt
    25561 gtgatttttt tgaaagaaaa aataaaatga aaacgaaaaa acatagatta cttgctctag
    25621 ctcttatttc aagttttaca ttattgggag ctgcatcagc tgctgtataa tatccagatg
    25681 gaggagtatg gacatatgga gaaggttcag gaggtggtta ggctttttca aattactatc
    25741 atggtaaaaa atatcattat tcatccatcg tgagcagatg ggatggtcat tctgataaag
    25801 gagaagctcc tgctggaaaa acctcctatg catggatttg gactaaatgg ggagaacaag
    25861 tagcatttta ctgtgattat gactaatcgt tcattgattt aaatcgttcc ccttgtaaga
    25921 aattacaggg ggaattttgt ttacaaggag tctaccaagg agtctactat gaagaaacta
    25981 ttcatattat tatcaacttt ttttctcagc ttcttccttg cttggattat tgtcttacgt
    26041 gcgccacaat atttatatgc aagctatgat tccgtttctt tacttcgtgt caaaaaagat
    26101 actcaggaac cgacgcgtga ggtatttgaa caggaattgg agaattttgc aaactcagaa
    26161 cagagtttaa tagctagaag aattgtagag ccgagtaagg atgggacgac tcactttact
    26221 tatgcaactt atggtcaggg aactttacca aaagaattcc aagaagctag ccaagaaagt
    26281 cgtgaacgta gtgatccgct aaatagttat ctccttttgt caggctcctt gacgaaagaa
    26341 aagcttgccg ataaattagg agatttgggt tataaagcaa gtgctgaccg aaagataccg
    26401 ccctattttc ttgcttttcg aatattacta aatcccctta ttttaattag tttagcaata
    26461 tttggcttat ctttctttgc tttagtgatt atcactcgga ttaaggaaat gagagcagca
    26521 ggtataaaac tcttttctgg tcagactctc ttatccatca tggggcattc tttatctact
    26581 gatatcaaat agctccttct atcagccctc ctttccttcc taggtggggg agtcgttctt
    26641 tttagtcaag gtttgtttta tcctatcttg ttagccacct atggttttgg gattagtttc
    26701 tatctgttgt ttttattggc gatttcaatt ttactaatgc ttctttatct aatgagtttg
    26761 agttacaaag cattagttcc cgttattaag gggagattac cccttaaacg cctgatgatt
    26821 ttaaccctat tgtgtcagtt ggttgctgtc tttacagtag gatacgctgt taagacaggt
    26881 ttgacgtctt accaacgatt gaaagaactt gaaatttcaa aacaagcatg gcaggataga
    26941 gcagactatt atcaaatttc ttttggctta ggtgatagag gaaaagatac agaaaatcag
    27001 agcaagtggt atgcctttgc caaggaagca atcgaagagg aacaagctct ttatgtaaag
    27061 gataatctgc tccattttgc caatccacaa ggaaaaaatg aacagggaga gacactggat
    27121 acctatagtc cagatgctaa tacgctctat gttagtccca gttatttgga caaggaaaag
    27181 gtcgtggtag atgctgagac caaacagaag ttagcccatc tccaaaaagg tgagtttatc
    27241 ctcttgctcc cagaacattt gcgctctcga gaagcagaac ttaagaaagt ttttgaagaa
    27301 agattgagtt attatggaaa atctggtgag gaggcaagtg ctcctttgga ttatgagatg
    27361 aaagcgcacg ttagttatct ttcaatggga gaaaagcggt ttgtttataa taacggtgag
    27421 aatcccgtat ctactcagta tttgactgat ccgattttag tggtattcac gccgacttct
    27481 acaggtgata gttttatatc cttatctagt tggtctatca atgctggaaa acaactcttt
    27541 atcaaaggat atgagagtgg gctagaactc ttgaagaaag ctggaattta tgagcaagta
    27601 tcctatctta aagaaggaag aagtgtttat ctaactcgtt ataatgaagt tcaaactgaa
    27661 acagcaactt taatcttagg agctattgtg gggatagcta gttccttgtt actattttat
    27721 tctgtcaatc ttctatattt cgagcaattc cgccgagata tcttgattaa acgaatttca
    27781 ggtttacgat tttttgaaac acatgctcag tatatggtta gccaatttgc cagttttgta
    27841 tttggtgcta gtctctttat tttaagcagt cgagacttgg tgattggctt gctcacttta
    27901 ttggtctttc tagctagtgc agttttgacg ctttaccgtc aagcgcagaa agaatctcgt
    27961 gtttctatga caattatgaa aggaaaatag gatgattgaa ctaaagaata tatctaaaaa
    28021 atttggaagc cgtcagctat tttcagatac gaatcttcat tttgaaggtg ggaaaattta
    28081 tgccttaatc ggtacaagtg gctgtggtaa gacaacactc ttgaatatga ttggacgatt
    28141 ggagccatat gacaaagggc aaatcatcta tgatggcact tctcttaagg acatcaagcc
    28201 ttctgttttc tttagagatt acttaggata cttatttcaa gattttggct taattgaaag
    28261 ccaaaccgtc aaagagaatc tcaatctggg tttagttggt aaaaagttga aggaaaaaga
    28321 gaaaatctct ttgatgaaac aagctctaaa ctgtgtaaac ctctcttatt tggatttgaa
    28381 gcaacctata tttgagttat caggaggaga agcacaacgt gttgcactag cgaagataat
    28441 tttaaaggat ccgcctttga ttcttgcaga tgaaccaacc gcttccttag accccaaaaa
    28501 ttctgaggaa ttactttcca tcctagaatc tttaaaaaat ccgaatcgga ccattattat
    28561 tgcgacccac aatcctctga tttgggagca agtggatcag gtcattcgag ttaccgattt
    28621 atcacataga tgatatggta agattcagtt agaagaaaga gtcacaaaca cactttgtgg
    28681 cttttttatt tccataaaaa tggtaaaata gtaggagtag aaatggagtt cgagacatga
    28741 aagtaataga tcaatttaaa aataagaaag ttcttgtttt aggtttggcc aagtctggtg
    28801 aatctgcggc tcgtttgttg gacaagttag gtgccattgt gacagtaaat gatgggaaac
    28861 cattcgagga caatccagct gcccaatgtt tgctggaaga agggatcaag gtcattacag
    28921 gtggccatcc tttggaactc ttggatgaag agtttgccct catggtaaaa aatccaggta
    28981 tcccctacag caatcccatg attgaaaagg ctttggccaa gggaattcca gtcttgactg
    29041 aggtggaatt ggcttatttg atttcagaag caccgattat tggtatcaca ggatcgaacg
    29101 gtaagacaac cacaacgact atgattgggg aagttttgac tgctgctggg caacatggtc
    29161 ttttatcagg gaatatcggc tatcctgcca gtcaggttgc tcaaatagca tcagataagg
    29221 acacgcttgt tatggaactt tcttctttcc aactcatggg tgttcaagaa ttccatccag
    29281 agattgcggt tattaccaac ctcatgccaa ctcatatcga ttatcatgga ttatttgagg
    29341 aatatgtagc agccaagtgg aatatccaga acaagatgac agcagctgat ttccttgtct
    29401 tgaactttaa tcaagacttg gtaaaagact tggcttccaa gacagaagcc actgttgtac
    29461 cattttcaac acttgaaaag gttgatggag cttatctgga agatggtcaa ctctacttcc
    29521 gtggtgaagt agtcatggca gcgaatgaaa tcggtgttcc aggtagccac aatgtggaaa
    29581 atgcccttgc gactattgct gtagccaagc ttcgtgatgt ggacaatcaa accatcaagg
    29641 aaactctttc agccttcggt ggtgtcaaac accgtctcca gtttgtggat gacatcaagg
    29701 gtgttaaatt ctataacgac agtaaatcaa ctaatatctt ggctactcaa aaagccttat
    29761 caggatttga caacagcaag gtcgtcttga ttgcaggtgg tttggaccgt ggcaatgagt
    29821 ttgacgaatt ggtgccagac attactggac tcaagaagat ggtcatcctg ggtcaatctg
    29881 cagaacgtgt caaacgggca gcagacaagg ctggtgtcgc ttatgtggag gcgacagata
    29941 ttgcagatgc gacccgcaag gcctatgagc ttgcgactca aggagatgtg gttcttctta
    30001 gtcctgccaa tgccagctgg gatatgtatg ctaactttga agtacgtggc gacctcttta
    30061 tcgacacagt agcggagtta aaagaataaa atatgaaaaa aattgtcttt acaggtgggg
    30121 ggacggttgg acacgttacc ctcaatcttt tgttaatgcc caagttcatc gaagatggtt
    30181 gggaagtcca ctatatcggg gacaagcgtg gtatcgaaca ccaagaaatc cttaagtcag
    30241 gtttggatgt cactttccac tccattgcga ctgggaaatt gcgtcgctat ttctcttggc
    30301 aaaatatgct ggacgtcttc aaagttggct ggggaatcgt ccaatcgctc tttatcatgt
    30361 tgcgacttcg tccacagacc cttttttcaa aggggggctt tgtctcagta ccgcctgtta
    30421 tcgcagcgcg tgtgtcagga gtgcctgtct ttattcacga atctgacctg tctatgggct
    30481 tggccaataa aatcgcctat aaatttgcga ctaagatgta ttcaaccttt gagcaagctt
    30541 cgagtttgtc taaggttgag catgtgggag cagtgaccaa ggtttcagat caaaaaaatc
    30601 cagaaccaga tgaattggtg gatattcaaa cccactttaa tcataaattg ccgactgtat
    30661 tgtttgttgg cggttctgca ggtgctcgtg tctttaacca attggtgaca gaccataaga
    30721 aagaactaac agagcgctac aatattatca atctaactgg agattctagc ctgaatgagt
    30781 tgagccaaaa tctttttcgt gttgactatg tgaccgatct ctatcaaccc ttgttggaat
    30841 tggctgatat tgttgtgaca cgaggtggtg ccaatacgat ttttgagctc ttggcgatag
    30901 caaaattgca tgtcattgtg ccgcttggtc gtgaagctag tcgtggtgac cagattgaaa
    30961 atgcagctta ctttgtaaaa aaaggctatg cagaagacct tcaagaaagc gatttgacct
    31021 tggatagttt ggaagagaag ctttctcact tactaagtca caaggaagat taccaagcta
    31081 agatgaaagc ttctaaggaa ttgaaatctc tagcagattt ttatcaattg ttgaaaaaag
    31141 atttatcata aggaaagtaa atgtcaaaag ataagaaaaa tgaggacaaa gaaatcctcg
    31201 aagaattgaa agagttatca gaatggcaga aacgaaacca agaatatcta aaaaagaagg
    31261 ctgaagaaga agcggctcta gctgaggaga aggaaaagga aagacaagct cggatgggag
    31321 aagaatctga gaagtcagag gacaaacagg accaggagag tgaaacagac caggaagatt
    31381 cagaatcagc taaggaagag tctgaagaaa aagtagcatc ctcagaggat gacaaagaga
    31441 aagaagagaa agaagaacca gagtctaaag agaaggagga acaggataaa aagcttgcta
    31501 aaaaggctac aaaggaaaaa ccagccaaag caaagattcc tggtatccat atcttgcgag
    31561 ccttcacgat tttatttcca agtctgcttt tattgattgt ctctgcctac ttgctcagtc
    31621 cttatgcgac catgaaagat attcgtgttg agggaacggt gcaaactaca gctgatgata
    31681 ttcgacaggc ttcaggcatt caggattcgg attatacgat taaccttctg ctagacaagg
    31741 caaaatatga aaagcagatt aagtctaact attgggttga atcagctcaa cttgtctatc
    31801 aatttccaac taagttcact attaaggtca aggaatatga tattgtggcc tactatattt
    31861 ctggtgaaaa tcattatcct attctttcca gtggtcagct tgagactagt tctgtgagtc
    31921 tgaacagttt accagaaact tatttatcag ttctctttaa tgatagtgaa caaatcaagg
    31981 tttttgtctc agaacttgct caaattagcc cagaactcaa ggcgactatc caaaaggtgg
    32041 aattagcccc aagcaaggtg acatccgatt taattcgatt gaccatgaat gattcggacg
    32101 aagtcttggt tcctctatct gaaatgagta agaaactgcc atattacagt aagattaagc
    32161 ctcaattgtc agaaccgagt gtggtcgaca tggaagctgg aatctacagc tacactgtgg
    32221 cggataaatt aattatggaa gctgaggaaa aagccaaaca agaggccaag gaagccgaga
    32281 aaaaacagga agaagaacag aaaaaacaag aggaagagag caattgaaat caaacgaccc
    32341 agcgctcatt gcgtcgctag gtttaccttt tctcttatag ttctttagtg accatgtttt
    32401 tacttgacaa gtgctagtag aaataataga ataatagaaa acctttaaag cagtccagag
    32461 aggcagctaa ggttagacgg tgaaagggtg gagactaccc atttttcgtg gaaccttgct
    32521 gttggcaggt tccttttttc gtggcttctg ttggccagac tctctcacta gtaaaggtaa
    32581 aaggagaaac ctatgcgaga acatcgtcca atcattgctc ttgattttcc tagttttgag
    32641 gtggtcaagg aatttttagc tcttttccca gcagaagaaa gcctttatct caaggtaggg
    32701 atggagcttt attacgcagc ggggcctgag attgtgtcct acttaaaagg tttgggtcat
    32761 agtgtctttt tggatctcaa acttcatgac attcccaata cagtcaagtc agcaatgaag
    32821 atcctatctc agcttggtgt ggatatgacc aatgttcatg cggctggtgg tgtagagatg
    32881 atgaaggctg cgcgtgaagg tcttggaagt caagctaaat tgatcgctgt aactcagctc
    32941 acatcaacgt cagaagctca gatgcaggag tttcaaaata tccaaaccag tctgcaagag
    33001 tctgtgattc actatgccaa gaagacagct gaagctggct tggatggtgt tgtttgctcg
    33061 gctcaggaag tacaagtcat caagcaggct accaatccag attttatctg tctgacacca
    33121 gggattcgtc cagctggtgt tgcagttgga gatcaaaaac gagtcatgac acctgctgat
    33181 gcctatcaaa tcggcagtga ctatatcgta gtgggacgtc ccattaccca agctgaggat
    33241 cctgttgcag cttatcatgc catcaaggat gaatggacac aggactggaa ttaaagaact
    33301 agattagaaa aataaaagga gaataccatg acacttgcta aagatatcgc tagccacctc
    33361 ttgaaaatcc aagccgttta cctcaaacca gaggaaccct tcacttgggc atctggtatc
    33421 aagtcaccga tttacactga taatcgtgtg acactagcct atccagaaac tcgtacccta
    33481 attgaaaatg gttttgtgga tgctatcaaa gaagcctttc ctgaagtaga agtgattgca
    33541 ggaactgcaa cagcagggat tccacacgga gccattattg ctgataagat ggacttgcct
    33601 tttgcctaca tccgtagcaa accaaaagac catggagctg gtaatcaaat cgaaggtcgc
    33661 gtagctcaag gtcaaaaaat ggtagtggtt gaagacctta tttcaacggg tggttcagtt
    33721 cttgaagctg tagcagcagc caagcgagaa ggagcagatg tgcttggagt tgtagcgatt
    33781 ttcagctacc aattgccaaa agcagataag aactttgcag atgctggtgt taaacttgtg
    33841 acgctttcaa actatagcga gcttatccat ctagcccaag aagaaggtta catcacgcca
    33901 gagggccttg atcttctaaa acgctttaaa gaagaccaaa aaaattggca agaaggttag
    33961 gtcagtaaga taaagagaga cgaggctacc gagcctcttt taccatttta tttaaaatat
    34021 gacaatattt taaataaaat gattgacaac gctttctttt attgatataa tgaaaatgta
    34081 atatgtatca aattgatcaa tcaactatct tgtttaccac ttcttaggag gacgatgtca
    34141 tgaaaagaag aaaaatatat tccttttttg cgtagttaca attgcatcta gtttgtttct
    34201 ccctacagtt ttagctagac agattggaaa ttatgattta acgttgccgc gttggggttc
    34261 ggatacaact agtgagcttg agaaagaaaa cgcctctgct ggaattaata ataatgacag
    34321 cactggtggc ggtaaaaggt taaatacctc tattcgtagc gcctatagtg ggtcagatat
    34381 taccccggta tattcattgg ggtctggctc taggattgtc atgtactata atggaggtgg
    34441 tgacaattat attggttctg gtactagatt agctatggcg ccacaattta gaaatcatgt
    34501 aagaattcat acttcaggtt cttggagtcc agattcttat taacttactt gtcagagtaa
    34561 gccttaaaga tggttgattg tgggtgtagc atgaaaaaag aatgctacac cctattttta
    34621 ttataaggag gagtaaggat ggaatttttc atttgtaatc ttgtacgagt cgttcaatca
    34681 cctcgatttt atatgtcttt atttttgacc cttctttgca tgagtttagg aaatttcctt
    34741 gctttcaatg gtatttataa aattgaaggt ttatcgattt tttttgccgc ttcttctatt
    34801 cgaggatttt caccgattag cctagtagct gcacttatct gtacactgcc ctattctagt
    34861 cagataatag aggatgctga gagtcatttt ctaacagcac aattgtgtcg aatttctaaa
    34921 aagaagtatc tggctattgt gggtagtact gcaattattt cttcttttct agtctttttt
    34981 ctcccctatt tattattatt aggaattaat cttttagtga ctccttatca ggaaatttat
    35041 attggagatt atagtggtgc cttaaaagaa ttatttgatt ccaatcagtt gctctatagt
    35101 cttgtgacga ctctctggta tggagtttgg ggcgctgtgt tctctatttt tggactagct
    35161 agtgctttgc tagtgaagaa aaaaatagga gctattttca tcccagttgc ctatatgatg
    35221 gttggtggta ttttttgggc tattttaggg ctatcttact tagaacctgt gacaacatta
    35281 gctttgggat atcagaaaga tatcagtctt tccttagtta gtgggcatct tgcttttatt
    35341 ttatttgtta gttgtttggt tgtttatggt acattttttc tacattcaga ggactatgta
    35401 taatgaaaca atttgttcaa ttttataaaa aagatttctt agcagtattg gtttatttta
    35461 tattactgct atcctgtgtt ttatctagta cagtatattt attgcgctgt cgccaatatt
    35521 caatccatcc aaatgtatta gaatggatct tagtcttact tcaagatatg acgactggag
    35581 tatactgctt tccgttcaca tatatattgt tcttttttta tttgatgaat aactatttta
    35641 ataggttgga gtgtcgcatt cgtctgaaat caattaagca ctttaccagt tttagtttca
    35701 aattagcagc tcttagtacg gggatttgga cggcgacttt atttttattg atttttctga
    35761 ttgcatttag taatggtttt agcttctctt tggagataaa ggaggttgat tttttaagag
    35821 aattttatgg tataagtatt gcaaacaatg ctagtttctt tataggattt tttttctctt
    35881 atatagcata ctatttcttt ttatccttac ttactattag cagtttttct tggtttaaaa
    35941 aatcaaacat gagcttagta tttctgttta cttttttatt tgtagaatcc ttattctgga
    36001 tttatcagtt ggacaatggg ataattggat tattgccaat ttttcagtat atggtaaatt
    36061 ccaatccgta tgcattgatt tattggctta cattactatc tatcataatt ccattgactg
    36121 tattttctgt tcatagaaac tggaggagag tgtaaaagtt ggaaatggga aagttaagta
    36181 gtcacatgtg gaggttgaat cagataatct ataccaagta cttttggggt tatgttcttt
    36241 tttggatatt gatttgttta ggattatggt attggttaga aggaaatgat agacttgtta
    36301 tagaaatttt aaaagggcct aatctgagtc aaaactcttt tttagtctta tctatatggt
    36361 tgcttcattg gtttattatt catacatttt ttctagcagt tgtatatcgt agaagagcat
    36421 ccgatttctt tatggaagtg attcgatttt cttctattaa gctctggatt aggtatcaga
    36481 tttggacctg ttttctttat ggactcattt taatcatggt aaaagttcta gtgattcaat
    36541 ttatgttaca gttaccaaac tgggatatag gagttttgtt tatagttgat tttttgaatg
    36601 cttgtgtgtt agtcttgttt tgctttatgt tatacgcact aggagcgaat gtacaaatga
    36661 actttgcttg cgttagtttc tttttactca tgattgtgtt tggtggtcta tttgtaggaa
    36721 atcgaactaa ttatctattt tatattttaa atcgagggaa tggagatata ggacgagatt
    36781 tatttcttca gttgctattt ttagtctttc tttttaaaag cattttctat ttcactcgtc
    36841 aaaagaggag gtttatagaa tgaatgaaat aattacatta aaaaatattc agttggaatt
    36901 aaaaaaaaca tgtgtttttc aaaaccttaa ttttagttgt aaacaggggg aaattatagg
    36961 aattactggt gcgaatggct cagggaaaag tgtattgttt aaattaatag ctggtttata
    37021 tagtccgtct tatggagaag tgttaatcaa tggggaaaat attgttcctg agagaaaaat
    37081 tccagctaat ttgggagctt tgattgaaga acctggtttt ataaattatt atagtggctt
    37141 taagaattta caatatttgg caagcatacg aggagtagtt ggtaatcagg aaatcaatga
    37201 tacactgaaa atagttggtc tatatgagca aaaagaccag aaagttaaaa cttattcgct
    37261 aggtatgagg aaaaagctag ggattgctca agcaattatg gagaatccct ctattctttt
    37321 actagatgaa cctatgaatg ccttggataa atcaagtgta gaaaatatga gaacattgtt
    37381 tagaaagctc tctagtgaaa aagggacaac aattttgatt gctagtcata gtgaagagga
    37441 tattcgtatc ttatgtgata aagtatatgc aatagaagat aaagtatgta cactgtgttc
    37501 agattgaaca tcttagatag actcaggatg ttataggtaa aatcttaaaa agggattgga
    37561 tcttaaaatc cagttccttt taagagttaa tgactaatca acttttccac cttcaacaac
    37621 caggtcatct gctttagcag cgtcaccgta ggttaggtga agtgtttttt cataggcctt
    37681 gtggaagaag ttttccttgc ctaatttttc aatatcttta ttgatgaagt ctagcaattc
    37741 ttggttgcct ttttgaactg ctgccgcaat ggtatcggga tcaccgaggg aagtaattcc
    37801 tacttcaaat cctttatttt caagcgccca agctagaact tccgtattgt cagttgaaaa
    37861 ggcatctcca cgtccgtcaa gaagagcttg gtaagagtca ctgtattggt cgtatttttg
    37921 gagtttgatt tctggatgat tcttttcaaa ataagtctca gcagtcgttc cttttgtgac
    37981 aattaaggtt ttaccttcaa gttgtttgac gtctgtaatg agaccagtct taggtgatac
    38041 gacacccaga gaaactttca tatatggaag ggcaaaatca acttgtttct tacgttcgtc
    38101 agttactgta aagttagcaa gagtaatatc taccttgttt gaaatcaagt attccgcacg
    38161 gttggcagca tcgactgaaa tgtatttaac cttgacacca aggtcttgag ctagttggtt
    38221 ccctagttca atatcgtagc cttggtaaga accatcattg tcaacgtagc caaacggttt
    38281 tttatctcca aacacggcga ttcgcagttc accgcttttt ttgatttcat cgatagtgcg
    38341 agctttggca gttgtttttc cagaggatga accagcgttt ccacctgagc tacaagcagt
    38401 gataaagata agggcaaagg caagtgctaa aacagttaag agtggtttga atagtttcat
    38461 aagaatctcc tttatagata tgagccgaat tggctaaagt caaagacgtt taaaaattcc
    38521 tgggctcgtt tggtttgcgg attggtaaag aaggcttgag ctgttccttc ttcagcgatt
    38581 ttcccttggt cgaggaagat aatccggtca gcaatggctt gggcaaactg catttcgtgg
    38641 gttactaaaa tcatggtacg gccttcttgg gccaaatcat tgataagttc cagcacctca
    38701 cgcaccattt ctggatccag cgaagcagtc acctcgtcaa aaaggatgat ttctggatgc
    38761 attaggaggg cacggacaat tgcaacacgt tgcttctgtc caccagataa ttgacgggca
    38821 aagcaaagct atgttgttta tccagtaaac cgacacgatc tagtaattgc aaagcttctt
    38881 ccgttacttc tttcttgtcc cttccttgag ctttgatagg gcctaggatg aggttttgta
    38941 agacatccag atggggaaag agttcataac tttgaaagac catgccaatc ttttggcgaa
    39001 ctaggtgaaa atctttttta ttttcaacga tagactgacc atccagaaga atatctccac
    39061 cttgaatact ttctaagccg ttgaggcaac gaaggagggt acttttccca caaccaaatg
    39121 gccctaggat gacaacaact tccccttttt tgatttctag agaaagtcct tggaggatgg
    39181 gattgtctcc gaaggatttt tttagttcct tgatttctaa gatagtttca gacatttagt
    39241 ttctccaatg tttttctaag tgagtggata gtttggaaat agggtagcaa actgcgaaat
    39301 ataagactag aatggttcca taaatccaaa atgaagcagt tgggatggtc aggcgattgc
    39361 tatcgatgat ttgttgtcca actttggtca cttccacaac cccaatcaaa acaactaatg
    39421 aagtggtttt aatcatccga gtgacaagat tgatagcctg cggtagcagt cttcttaaga
    39481 cttgtgggat gatgatgtgg tagtaaagtt gaacattagt caagccgagt gcctatccac
    39541 tttcaaactg atgtttaggg agagaagtga tagctccacg taccaagtct cccatttcag
    39601 ctgttcccca gagggtaaaa atgataatag ctgaagtctc acctgagata ttgatattaa
    39661 agtttcgagc caagccaaag taaacgatga agagtagcac cagctggggc atgatacgga
    39721 taaattccag atacaatcgt gttaaaaatc gtatgattct agaatgggag gtcatgatga
    39781 ttcccatgac tgttccgaac atcatggata agaggacaga caggatggat atcccaatcg
    39841 taacgcccaa cccctgtaag attctcagga gattatttcc ttgaaagagt acttggattc
    39901 ccgaatcctg catggcgggt cctcctttct atccagctaa agaccagtga gatgggtagc
    39961 agcatgatca gataagcaac taccaacata gctagcgcaa tgtctgtctc atagtagaga
    40021 ccaatcaaat ccttggcgac gtacatgagg tcggccaaag ccactgctga gaaaacagag
    40081 gttttcttga taaggaaaat gacattggca ctaaaggagg ggagtaccac cgctgttgct
    40141 tgcggaagaa ccacatagcg aaagacctgt agaggtgtca gaccaatagc gaggccaatc
    40201 tcctgctggg tttgactgat ggcttccagc ccacttcgga aagattctgc catataggag
    40261 cctcctaaaa agacaagtcc aagcgttgca cagacttctg aagataggac aatcccgatt
    40321 cggggaagac cgaagtagag aaagaagagt tgaatcaaaa ggggcgtatt acgtgacaat
    40381 tcaatgtagg ctgtcgctac ttgcgctaaa acagggattc gataatgtcg gatgatacta
    40441 acgattaaac cgagcagaaa ggatcccaaa attccccaaa ctgcaatatg caaggtcaga
    40501 aagaatgcct tttgatatag tggtagatat tgttcaacaa tggatcaatc caaaaataga
    40561 acctcccatc tagaaataat acagttattg tagcacttaa aatcttcttt ggataatatc
    40621 tattttt
//
LOCUS       DAVLHB010000014        40320 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLHB010000014 DAVLHB010000000
VERSION     DAVLHB010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.014"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            5..75
                     /locus_tag="VXE36_000845"
     tRNA            5..75
                     /locus_tag="VXE36_000845"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VXE36_000846"
     tRNA            110..183
                     /locus_tag="VXE36_000846"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VXE36_000847"
     tRNA            266..355
                     /locus_tag="VXE36_000847"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VXE36_000848"
     tRNA            366..439
                     /locus_tag="VXE36_000848"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VXE36_000849"
     tRNA            443..515
                     /locus_tag="VXE36_000849"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VXE36_000850"
     tRNA            528..608
                     /locus_tag="VXE36_000850"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VXE36_000851"
     tRNA            613..683
                     /locus_tag="VXE36_000851"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VXE36_000852"
     tRNA            698..770
                     /locus_tag="VXE36_000852"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            784..855
                     /locus_tag="VXE36_000853"
     tRNA            784..855
                     /locus_tag="VXE36_000853"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:816..818,aa:Gln,seq:ttg)
     gene            865..948
                     /locus_tag="VXE36_000854"
     tRNA            865..948
                     /locus_tag="VXE36_000854"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:899..901,aa:Leu,seq:caa)
     gene            1055..2332
                     /locus_tag="VXE36_000855"
     CDS             1055..2332
                     /locus_tag="VXE36_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0779182.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2408..3892
                     /locus_tag="VXE36_000856"
     CDS             2408..3892
                     /locus_tag="VXE36_000856"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0779183.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3953..5233
                     /locus_tag="VXE36_000857"
     CDS             3953..5233
                     /locus_tag="VXE36_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0779184.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5237..5857
                     /locus_tag="VXE36_000858"
     CDS             5237..5857
                     /locus_tag="VXE36_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0779185.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6023..7134
                     /locus_tag="VXE36_000859"
                     /pseudo
     CDS             6023..7134
                     /locus_tag="VXE36_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            7457..7882
                     /locus_tag="VXE36_000860"
     CDS             7457..7882
                     /locus_tag="VXE36_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0779186.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7893..8252
                     /locus_tag="VXE36_000861"
     CDS             7893..8252
                     /locus_tag="VXE36_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV0779187.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8359..9003
                     /gene="pcp"
                     /locus_tag="VXE36_000862"
     CDS             8359..9003
                     /gene="pcp"
                     /locus_tag="VXE36_000862"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0779188.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9031..9888)
                     /locus_tag="VXE36_000863"
     CDS             complement(9031..9888)
                     /locus_tag="VXE36_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0779189.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10018..11160
                     /gene="tgt"
                     /locus_tag="VXE36_000864"
     CDS             10018..11160
                     /gene="tgt"
                     /locus_tag="VXE36_000864"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0779190.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11258..13075
                     /locus_tag="VXE36_000865"
     CDS             11258..13075
                     /locus_tag="VXE36_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0779191.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSVAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13228..14379
                     /gene="nagA"
                     /locus_tag="VXE36_000866"
     CDS             13228..14379
                     /gene="nagA"
                     /locus_tag="VXE36_000866"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0779192.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14542..15600
                     /locus_tag="VXE36_000867"
     CDS             14542..15600
                     /locus_tag="VXE36_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0779193.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15751..16116
                     /locus_tag="VXE36_000868"
     CDS             15751..16116
                     /locus_tag="VXE36_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0779194.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16191..17132
                     /locus_tag="VXE36_000869"
     CDS             16191..17132
                     /locus_tag="VXE36_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0779195.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17080..18096
                     /locus_tag="VXE36_000870"
     CDS             17080..18096
                     /locus_tag="VXE36_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0779196.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18098..18424
                     /locus_tag="VXE36_000871"
     CDS             18098..18424
                     /locus_tag="VXE36_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEV0779197.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18393..18821
                     /locus_tag="VXE36_000872"
     CDS             18393..18821
                     /locus_tag="VXE36_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0779198.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18826..19086
                     /locus_tag="VXE36_000873"
     CDS             18826..19086
                     /locus_tag="VXE36_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779199.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19049..19510
                     /locus_tag="VXE36_000874"
     CDS             19049..19510
                     /locus_tag="VXE36_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0779200.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIHRVEKEKS"
     gene            19488..19901
                     /locus_tag="VXE36_000875"
     CDS             19488..19901
                     /locus_tag="VXE36_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0779201.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20038..20632
                     /locus_tag="VXE36_000876"
                     /pseudo
     CDS             20038..20632
                     /locus_tag="VXE36_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20693..21646
                     /locus_tag="VXE36_000877"
     CDS             20693..21646
                     /locus_tag="VXE36_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0779202.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21697..22887
                     /locus_tag="VXE36_000878"
     CDS             21697..22887
                     /locus_tag="VXE36_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0779203.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23036..23407
                     /gene="rnpA"
                     /locus_tag="VXE36_000879"
     CDS             23036..23407
                     /gene="rnpA"
                     /locus_tag="VXE36_000879"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0779204.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23382..24206
                     /locus_tag="VXE36_000880"
     CDS             23382..24206
                     /locus_tag="VXE36_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0779205.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24225..25211
                     /locus_tag="VXE36_000881"
     CDS             24225..25211
                     /locus_tag="VXE36_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0779206.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25262..25885
                     /locus_tag="VXE36_000882"
     CDS             25262..25885
                     /locus_tag="VXE36_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0779207.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26016..27473
                     /locus_tag="VXE36_000883"
     CDS             26016..27473
                     /locus_tag="VXE36_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0779208.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFWLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27496..27777
                     /locus_tag="VXE36_000884"
     CDS             27496..27777
                     /locus_tag="VXE36_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0779209.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27854..28339
                     /locus_tag="VXE36_000885"
     CDS             27854..28339
                     /locus_tag="VXE36_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0779210.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28356..29021
                     /locus_tag="VXE36_000886"
     CDS             28356..29021
                     /locus_tag="VXE36_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0779211.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29025..29888
                     /locus_tag="VXE36_000887"
     CDS             29025..29888
                     /locus_tag="VXE36_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0779212.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKSCDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29890..30594
                     /locus_tag="VXE36_000888"
     CDS             29890..30594
                     /locus_tag="VXE36_000888"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0779213.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30773..32446
                     /locus_tag="VXE36_000889"
     CDS             30773..32446
                     /locus_tag="VXE36_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0779214.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            32558..33649
                     /gene="ulaG"
                     /locus_tag="VXE36_000890"
     CDS             32558..33649
                     /gene="ulaG"
                     /locus_tag="VXE36_000890"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0779215.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33763..35739
                     /gene="tkt"
                     /locus_tag="VXE36_000891"
     CDS             33763..35739
                     /gene="tkt"
                     /locus_tag="VXE36_000891"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0779216.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35856..36155
                     /gene="yajC"
                     /locus_tag="VXE36_000892"
     CDS             35856..36155
                     /gene="yajC"
                     /locus_tag="VXE36_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0779217.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36202..36630
                     /locus_tag="VXE36_000893"
     CDS             36202..36630
                     /locus_tag="VXE36_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0779218.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36632..37042
                     /locus_tag="VXE36_000894"
     CDS             36632..37042
                     /locus_tag="VXE36_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779219.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37359..40010
                     /gene="adhE"
                     /locus_tag="VXE36_000895"
                     /gene_synonym="adhC"
     CDS             37359..40010
                     /gene="adhE"
                     /locus_tag="VXE36_000895"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0779220.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12235 a         7225 c         9084 g        11776 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tattggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga
      841 atccagctac cccagttact atttgccggc gtggcggaat tggcagacgc gctggactca
      901 aaatccagtg tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt
      961 aggaacgttg ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc
     1021 aaattttatt tagattaaga aagtgtaggg gagtatgtct tgttctatcg atttattaaa
     1081 acatcggtat ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga
     1141 gtatcctgtt gcaagtttag aaggggatgc tacagatgtt gaagttatga aggatctatt
     1201 tcattattta gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct
     1261 gatccagtta gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac
     1321 gattgagttt gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa
     1381 ttatatgaat gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg
     1441 tatccatccc aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat
     1501 gttgatggat tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc
     1561 tgaatatggt acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta
     1621 cttacgggtg attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa
     1681 ctctgaattt tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga
     1741 atctatgcat ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga
     1801 agctgatttt tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca
     1861 gacctattat ttttatccta ttcaggctgg ggactatttg gctacgtccg aaatccaagc
     1921 atttgctctg aatggggatg aggttattat ttacccccaa gagaaggatt ttgaaactca
     1981 tcgtagttac cagtaccaag atttaacgac tcgaggaaca gttgagtttc gtagtgtgtg
     2041 tacacagcca cttgatagga cttttgcttc tgcagctttt cacttgggat tattggttaa
     2101 tttagacaag ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga
     2161 ttacaagtct ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac
     2221 gattattgaa ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa
     2281 taaggaagaa atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt
     2341 ataaagggag aattttctga aaaatcatga tataatggac gagactatag ataaaggata
     2401 gagagtaatg acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag
     2461 ccaagcaatt ttgcaaggtt tggcgacgga cggcggtttg tttacaccgg atacttatcc
     2521 aaaggtagat ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct
     2581 agttttgtca gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa
     2641 tgcctacgat agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca
     2701 atacaatttg gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat
     2761 tttgccatac tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat
     2821 cttgacagcg acatctggtg acacggggaa agctgctatg gcggggtttg cgaatgtgcc
     2881 tggtactgag attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca
     2941 aatgaccact cagactggcg acaatactca tgttattgct attgatggta actttgacga
     3001 tgcgcaaaca aatgtgaagc acatgtttaa cgacgtggct cttcgtgaaa aattgactac
     3061 caacaagttg caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat
     3121 tgtttattat gtttatgctt acgctcaatt ggttaagact ggtgaaattg tagctggtga
     3181 aaaggttaac ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc
     3241 caaacaaatt ggtttgccag ttggtaaatt aatctgtgct tcaaatgaca acaatgtttt
     3301 gacagacttc tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag
     3361 cccatctatg gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg
     3421 aaataatgct gaaaagacaa ctgaacttat gaatgccttg aacacgcaag gacaatataa
     3481 gttgacagac tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga
     3541 agaaacggca gcagagatca agcgtgtttg tgagttagat tcttatatcg aggaccctca
     3601 tacagctgtt gcttcagcag tttataaaaa ataccaatcg gccactggag atgtaactaa
     3661 gacagtgatt gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt
     3721 aactggaaaa gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg
     3781 cgttgcagtg ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac
     3841 agtggcagct gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg
     3901 gagcaaactc ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa
     3961 gaaaaataaa gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat
     4021 gctaatggga atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg
     4081 ggtttcagta gctggtaata ttatcaccat ttatcaggcg attttcatcg ctctgggagc
     4141 tgctatttcc agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta
     4201 tcatgtgact gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc
     4261 catcttcgct gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag
     4321 tggtggactg tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag
     4381 tctaggagcc ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt
     4441 atccaatgcc ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat
     4501 agctggtgtt gcttggggga caattgtgtc tcgtttggtt ggtcttgtga ttttgtggtc
     4561 acaattaaaa ctgccttatg ggaagccaac ttttggttta gataaggaac tgttgacctt
     4621 ggctttacca gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc
     4681 cttggtcgtt tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac
     4741 ccagtttaac tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg
     4801 agcagttgga gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct
     4861 ttctctgttc ctcatgttgc ccctgtcctt tagtatatat gtcttgggtg taccattaac
     4921 tcatctctat acgactgatt ctctagcggt ggaggctagt gttctagtga cactgttttc
     4981 actacttggg acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt
     5041 aggaaatgca cgcctccctt tttatgcgac aagtatagga atgtggtgta tccgcattgg
     5101 gacaggatat ctgatgggga ttgtgcttgg ttggggcttg cctggtattt gggcagggtc
     5161 tctcttggat aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgag
     5221 cttgaaagga taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt
     5281 ggactcttac gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc
     5341 ttatgataag gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt
     5401 gcgggtggca gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag
     5461 tctggctgag aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg
     5521 ggcagacgaa tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac
     5581 cattctcaag gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg
     5641 ctttgtgcgg aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa
     5701 ttctgataat acttattata taggggatcg gactctggat gtggaatttg cccagaatag
     5761 tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc
     5821 gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt
     5881 gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat agacagttct
     5941 gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata gacaggtact
     6001 catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt
     6061 gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg cacgtagtgt
     6121 tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata ccgtacagta
     6181 tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtaacag tgcttgcgaa
     6241 tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga caacgactgt
     6301 caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag actctagtga
     6361 agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg atgatcaaac
     6421 tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag tgattgcttc
     6481 tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga ccgaaacaac
     6541 tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc aggaaacaca
     6601 agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag aagcaaaaga
     6661 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
     6721 aataatttaa caacttacga ggctccagct gcgcccgatt atgctggact tgcagtagca
     6781 aaatctgaaa atgcaggtct tcaaccacaa acagctgcct ttaaagaaga aattgctaac
     6841 ttgtttggca ttacatcctt tagtggttat cgtccaggag acagtggaga tcacggaaaa
     6901 ggtttggcta tcgactttat ggtaccagaa cgttcagaat taggggataa gattgcggaa
     6961 tatgctattc aaaatatggc cagccgtggc attagttaca tcatctggaa acaacgtttc
     7021 tatgctccat tcgatagcaa atatgggcca gctaacactt ggaacccaat gccagaccgt
     7081 ggtagtgtga cagaaaatca ctatgatcac gttcacgttt caatgaatgg ataaacccga
     7141 cttgataaca tcattttgac gaatgagatc tagctttcgt gatggaaagc gattctcgtt
     7201 cgttttttct ttgtcatact cttcgaaaat ctcttcaaac cacgtcagtt ttatctgaaa
     7261 cttcaaagct gtgctttgag caacctgcga ctagcttcct agtttgcttt ttgattttca
     7321 ttgagtatca atttgaatgg aaaatggaaa gttatcatct tgtaatgagt taagcaacat
     7381 tcttgcaatc tattttactt tatatcacaa ttaattagtc aaatattgat aaatcaataa
     7441 aaagagaggg gaagaaatgc tagagattca agatttactg tatcaactcc gcttgtctga
     7501 gcaagcgagt acgcaattgt ttgaaaaaag gcttgggatt agtttgacac ggtatcagat
     7561 tttactgttt ttgctggagc attctccttg taaccaaatg gcggttcagg agcgtttgaa
     7621 aattgatcag gctgctttga cacggcattt caaaattttg gaaacggaag gtttggtgga
     7681 gcgtcatcgt aatcctgaaa atcagcggga agtgttggta gaggctgcga agtatgccaa
     7741 ggagcagtta gtggtgaatc cccctctgca acatatcagg gttaaggaag agatagaaag
     7801 tatcttaaca gagtttgaga gaacagaact cagccgttta ttaaataaat tggttttggg
     7861 tattgaaaat atagaaattt aaggagaaat agatgtcaat tattttaaca acgatcgttg
     7921 ctttggagca tttttacatt ttttatttgg aaagtattgc cacgcaatca gatgcgacta
     7981 gtcgtgtatt taatatggaa aaggaagaat tggctcatcc gtcagtaagt tcattgttca
     8041 aaaatcaagg aatttataag gctctgctag gagtctttct cttgtatgtc atttatttct
     8101 cacagaattt agaaattgtg actatttttg tcttatttgt gattggtgct gcgacttacg
     8161 gctctttaac agcggataaa aaaattattt tgaaacaagg tggatcagct attttggcct
     8221 tgattagtat tttactcttt aaatacactt gaaggtcgat tctaatctcg ctaatccttt
     8281 ttaatccaga ataagggaaa tatgttatac ttgtttttaa gaaaaaagtc tcattgaatt
     8341 ggttttgagg agttagaaat gaaagtatta gtgacaggtt ttgagccctt tggaggggaa
     8401 aagggcaatc cagctttgga ggccattaaa ggtttaccag ctgaaatcca tggtgctgag
     8461 gtccgttggc tagaggtgcc gacagttttt cacaaatctg ctcaagtatt ggaagaagag
     8521 atgaatcgtt atcaacctga ctttgtcctt tgtattgggc aagctggtgg aagaactagt
     8581 ttgacacctg aacgagtgac cattaatcaa gacgatgcat gcatttctga taacgaagat
     8641 aatcaaccga ttgaccgtcc cattcgccca gatggtgctt cggcctactt tagtagtttg
     8701 ccgattaaag cgatggttca agctataaaa aaagagggct taccggcctc tgtttccaat
     8761 acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt ggtagaaaag
     8821 aaatctccat atgttaaggc aggttttatg catattcctt atatgatgga acaggtggtg
     8881 aacagaccga ctactccagc tatgagttta gtggatattc ggcgagggat agaagcagca
     8941 atcggcgcta taatagaaca tggagatcag gaactcaagt tggtaggcgg agaaactcat
     9001 tgatagaaaa aagcttgagg ggaaaaacct tcaagctttt ggacgttttc gggccaatac
     9061 tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa aactagcaat
     9121 gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta ggacaaagtg
     9181 ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc ttggtgggac
     9241 ctgtcctagg tctagactat aacagagaag aaattccacc tgtgaatagg cataatactg
     9301 tggaatatag aggatatttc ctacaatgat caagatgaga cttgcaagaa agtagagtcc
     9361 aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg gaaactcagg
     9421 atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt aaatcccaag
     9481 taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg tcaaaaaggt
     9541 ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg gctccgtttt
     9601 agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa tagtcccgat
     9661 aaaggagact agtagaggaa agaggtaggt ttgaagtatt tggccaagta tgctgaaaaa
     9721 tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac cagataagat
     9781 gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag cctgaaaatg
     9841 ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc tcttattata
     9901 ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa tcatacagtg
     9961 tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag gtaaaaaatg
    10021 tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg agctcgtctg
    10081 ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc agttgggaca
    10141 caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc gggaattatc
    10201 ctatcaaata cctatcatct ctggcttcgc cctggagatg aactcattgc acgcgctggt
    10261 ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg tggttttcag
    10321 gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt taaaaatcat
    10381 ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca gaataatctg
    10441 ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc ttatgactac
    10501 gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa ggctcaccgt
    10561 cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga agaccttcgc
    10621 cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat cggtggtttg
    10681 gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac tcaactgcta
    10741 cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt gatcgatggg
    10801 gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc tcgtaacggg
    10861 acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc tgaggacttt
    10921 acgccactgg atcctgagtg tgactgctac acatgtaata actatacacg cgcttacctt
    10981 cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta ccacaatctt
    11041 tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga caatctcttg
    11101 gaattccgtg agtattttgt ggaaaaatat ggctataata agtcaggacg taatttctaa
    11161 aatggaattg atataaaaaa atcctaagtt ttctcttagg atttttcttc tttttttgat
    11221 agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat ggttttcctt
    11281 gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga cgatctttcc
    11341 tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga ttacagctct
    11401 actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt ttagaagacg
    11461 cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc cttttacttt
    11521 cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg tcttaggctt
    11581 tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt tcattcctca
    11641 tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc tttggggatt
    11701 ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg ggatggtctt
    11761 tctcttatct gttgctgcct tcttgatcag tttcttctcc atgtttattg gtagttttct
    11821 agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc cattcttttt
    11881 gggaagtatg ttagcaacta ttgtaggtgt tcgtcagacg acttccctcg tcaagcagtt
    11941 ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct ttggtttcct
    12001 agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta tcggcttctt
    12061 gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac atgaaaagac
    12121 acatcatata caggagccga agattatcag ctttttagcg gatactagct atgcggttta
    12181 tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc ttcttgctgt
    12241 attactgact ctgatttgtt cttatggctt tgccagtctg tcattctatg tattggaacc
    12301 ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc cttatattca
    12361 cgcaattctt gtagcaggta caggaatctt gaccatcatt gtctgcacgg tgaccttgtt
    12421 ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga agcaagctgc
    12481 aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca gtttgggaat
    12541 tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata cagcactaca
    12601 gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca agaccgcaaa
    12661 tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg tcattgcgac
    12721 tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga aaaatcttcc
    12781 taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa aagagaccta
    12841 tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga caccttacat
    12901 tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg ctggaacaga
    12961 ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat tgtatgcaga
    13021 tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa aataacttgt
    13081 attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca aaaaataggt
    13141 ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa taaattgtag
    13201 aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga tcagtttttc
    13261 tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa gtttgggaaa
    13321 catgtagagc agattcctga aggggctgag gtgattgact atacaggtta tagcattgcc
    13381 ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat ggacaacaac
    13441 attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt taccagtttc
    13501 ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga aaatcttgga
    13561 aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga aggtccatat
    13621 ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc gggtgttgag
    13681 gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc ccttgcacca
    13741 gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt gacggttgct
    13801 cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc tggagcgagt
    13861 gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt gggtatggtt
    13921 ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg tcaccacgta
    13981 gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat cgctcttatc
    14041 acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg agaattccca
    14101 gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc aggttctatc
    14161 ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa tccgcatgaa
    14221 gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga cgtctgtggc
    14281 caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt ggaattggta
    14341 gcaacctatc tagatggcgt aaaacgttat caagcataag agagaaggca gaagttagag
    14401 actagcttct gcttttttat acagggtact ttactggtaa ataaaaagtt aaaaaaatca
    14461 caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa tattacaaat
    14521 aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg acttgcttct
    14581 tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt gcgtattgta
    14641 aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc tacttgccaa
    14701 agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg ggaaggagtt
    14761 tccaacttca aaaaaggcga caaggtcttg atttcttgcg tctgtgcctg tggtaaatgc
    14821 tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg gattttcggt
    14881 cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga taatactctt
    14941 taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga cattctgcct
    15001 actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag cgtagccatt
    15061 attggttcag gtccagttgg attggctgct cttttaacag cccaattcta ttcaccagct
    15121 aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc attcggtgcg
    15181 actcataagg ttaattcttc agaccctaaa aaagccatta aagaaattta tgatttgaca
    15241 gatggtcgtg gtgtggatgt cgctatcgaa gctgtaggga ttcctgaaac atttgatttc
    15301 tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca tggtaaacca
    15361 gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac tggtttggta
    15421 tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat tgaaccggaa
    15481 aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga agtcttcagt
    15541 aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc agaagcctaa
    15601 gtagtaaaaa tatttttgta cataagtaaa tagaaattca gtcatccatc agatggttgg
    15661 attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc ggaattggtt
    15721 ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat gtacggagat
    15781 tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag tagaaaattt
    15841 gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt ggaacaagaa
    15901 tcgcctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc ggaagaccaa
    15961 cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc tcttttgcag
    16021 gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca aaccagtcag
    16081 gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt ttggagttgc
    16141 tttttttatt tttctaacgc tttgcgaata gtataggtga ggaggtaagt atggttcaag
    16201 aaattgcaca agaaatcatt cgttcggctc ggaaaaaagg ggcgcaagac atttattttg
    16261 tccccaagtt agatgcctat gagcttcata tgagggtagg agacgagcgc tgtaaaattg
    16321 gtagctatga ttttgaaaag tttgcagccg ttatcagtca ctttaagttt gtggcgggta
    16381 tgaatgtggg agaaaaaaga cgtagtcaac tgggttcctg tgattatgcc tatgaccaga
    16441 agatggcgtc tctacgttta tctactgtag gcgattatcg ggggcatgag agtttggtta
    16501 tccgtttgtt gcacgatgag gagcaggact tgcatttttg gtttcaggat attgaagaat
    16561 taggcaagca gtacaggcaa cggggactct atctttttgc tggtccggtt gggagtggta
    16621 agacgacctt gatgcatgaa ttgtccaagt cactctttaa aggacagcaa gttatgtcca
    16681 tcgaagatcc tgtcgaaatc aagcaggacg acatgcttca gttgcagttg aacgaagcaa
    16741 tcggcctaac ctatgaaaat ctaatcaaac tttccttgcg tcatcgacca gatctcttga
    16801 ttatcggaga aattcgtgac agcgagacgg cgcgtgcagt ggtcagagct agtttgacag
    16861 gtgcgacagt cttttcaacc attcacgcca agagtatccg aggtgtttat gagcgtctgc
    16921 tggagttggg tgtgagtgaa gaagaattgg cagttgttct gcaaggagtc tgctaccaga
    16981 gattaatcgg gggaggagga atcgttgact ttgcaaacag agattatcaa gaacaccaag
    17041 cagccaagtg gaatgagcaa attgaccagc ttcttaaaga tggacatatc acaagtcttc
    17101 aggctgagac ggaaaaaatt agctacagct aagcaaaaaa atatcatcac cctatttaac
    17161 aatctctttt ctagcggttt tcatctggtg gagactatct cctttttaga taggagttcc
    17221 ttgttggaca agcagtgtgt gacccagatg cgtacaggct tgtctcaggg gaaatcattc
    17281 tcagaaatga tggaaagttt gggatgttca agtaccattg tcactcagtt atctctagct
    17341 gaagttcatg gcaatcttca cctgagtttg ggaaagatag aagaatatct agacaatctg
    17401 gccaaggtca agaaaaagtt aattgaagta gcgacctatc ctttgatttt gctgggtttt
    17461 cttctcttaa ttatgctggg gctacggaat tacctgctcc cacaactgga tagtagcaat
    17521 attgccaccc gaattatcgg taatctgcca caaatttttc taggcatggt agggcttgtt
    17581 tccgtgcttg cccttttagc actaactttt tataaaagaa gttctaagat gagtgtcttt
    17641 tctatcttag cacgccttcc ctttattgga atctttgtgc agacctactt gacagcctat
    17701 tatgcacgtg aatgggggaa tatgatttca cagggaatgg agctgacgca gatttttcaa
    17761 atgatgcagg aacaaggttc ccagctcttt aaagaaatcg gtcaagatct ggctcaaacc
    17821 ctgaaaaatg gccgtgaatt ttctcagacg ataggaacct atcctttctt taggaaggaa
    17881 ttgagtctca tcatagagta tggggaagtt aagtccaagc tgggtagtga gttggaaatc
    17941 tatgctgaaa aaacttggga agcctttttt acccgagtca accgcaccat gaatttggtg
    18001 cagccactgg tttttatctt tgtggcactg attatcgttt tactttatgc ggcaatgctc
    18061 atgcccatgt atcaaaatat ggaggtaaat ttttaaaatg aaaaaaatga tgacattctt
    18121 gaaaaaagct aaggttaaag cttttacatt ggtggagatg ttagtagtct tgctgattat
    18181 cagcgtgctt ttcttgctct ttgtacctaa tctgaccaag caaaaagaag cagtcaatga
    18241 caaaggaaaa gcagctgttg ttaaggtggt ggaaagccag gcagaacttt atagcttgga
    18301 taaaaatgaa gatgctactc tgagcaagtt acaaggagat gggcgcatca cggaagaaca
    18361 ggttaaagct tataatgaat actatactaa aaatggaggg gcaaatcgta aagtcaatga
    18421 ttaaggcctt taccatgctg gaaagtctct tggttttggg acttgtgagt atccttgcct
    18481 tgggcttatc cagctctgtc cagtccactt ttgcagcagt agaggagcag attttcttta
    18541 tggagtttga agaactctat cgggaaaccc aaaaacgcag tgtagccagt cagcaaaaga
    18601 ctagtctgaa cttggatggg cagatgatta gcaatggcag tcaaaagttg acagttccta
    18661 aaggaattca ggcaccatca ggccaaagta ttacatttga ccgagctggg ggcaattcgt
    18721 ccctggctaa ggttgaattt cagaccagta aaggagcgat tcgctatcaa ttatatctag
    18781 gaaatggaaa aattaaacgc attaaggaaa caaaaaatta gggcagtgat tttactggaa
    18841 gcagtagtcg ctctagctat ctttgccagc attgcgaccc tccttttggg acaaattcaa
    18901 aaaaataggc aagaggaagc aaaaatcttg caaaaggaag aagtcttgag ggtagctaag
    18961 atggccctgc agacggggca aaatcaggta agcatcaacg gagttgagat tcaggtattt
    19021 tctagtgaaa aaggattgga ggtctaccat ggttcagaac agttgttggc aatcaaagag
    19081 ccataaggtc aaggctttta ccttgttaga atccctgctt gccctcattg tcatcagtgg
    19141 gggattactc ctttttcaag ctatgagtca gctcctcatt tcagaagttc gctaccagca
    19201 acaaagcgag caaaaggagt ggctcttgtt tgtggaccaa cttgaggtag aattagaccg
    19261 ttcgcagttc gaaaaagtag aaggcaatcg cctatacatg aagcaagatg gcaaggacat
    19321 cgccatcggt aagtcaaagt cagatgattt ccgtaaaacg aatgctcgtg gtcgaggtta
    19381 tcagcctatg gtttatggac tcaaatctgt acggattaca gaggacaatc aactggttcg
    19441 ctttcatttc cagttccaaa aaggcttaga aagggagttc atccatcgtg tggaaaaaga
    19501 aaaaagttaa ggcaggtgtt ctcctctacg cagtcaccat agcagccatc tttagtcttt
    19561 tgttgcaatt ttatttgaac cgacaagtcg cccactatca agactatgct ttgaataaag
    19621 aaaaattggt tgcttttgct atggctaaac gaaccaaaga taaggttgag caagaaagtg
    19681 gggaacagtt ttttaatcta ggtcaggtaa gctatcaaaa caagaaaact ggcttagtga
    19741 cgagggttcg tacggataag agccaatatg agtttctgtt tccttcagtc aaaatcaaag
    19801 aagagaaaag agataaaaag gaagaggtag cgaccgattc aagcgaaaaa gtggagaaga
    19861 aaaaatcaga agagaagcct gaaaagaaag agaattcata gtcaattcaa ctataatgcg
    19921 ttgaatccag aatagtccac tgtagtttct agaaaattgc tggaaatgga tgttaagctc
    19981 caattcattt gtttatatct tatttcagtt tactatactt tgtgctaaat taaagatatg
    20041 aaacatgatt ttaaccacaa agcagaaact ttcgattccc ctaaaaatat cttcctcgca
    20101 aacttggtat gtcaagcagc cgagaaacag attgatcttc tatcagacaa agaaatttta
    20161 gatttcggtg gtggcacggg tctattagcc ttgcccctaa cccctagcca agcaggctaa
    20221 gtcagtcact cttgtagaca tttctgagaa aatgttggag caagctcgtt tgaaagtgga
    20281 gcagcaagca atcaagaata tccagttttt ggagcaagat ttaccgaaaa atcccttgga
    20341 gaaagagttt gattgccttg ctgttagtcg ggttcttcat catatgcctg atttggatgc
    20401 ggctctctca ctgtttcatc aacatttgaa ggaagatggg aaactcatca ttgctgattt
    20461 taccaagaca gaagctaatc atcatggatt tgatttagct gaactggaaa acaagctaat
    20521 tgagcatggt ttttcatctg tgcatagtca gattctctat agtgctgaag acctgtttca
    20581 aggaaatcac tcagaattct ttttaatagt agcccaaaaa tcactcgcct agtcagggag
    20641 tgatttttct ataaggatgg aaaaaagaag ggaaatttgg taagatagga atatggattt
    20701 tgaaaaaatt gaacaagctt atacctattt actagagaat gtccaagtca tccaaagtga
    20761 tttggcgacc aacttttatg acgccttggt ggagcaaaat agcatctatc tggatggtga
    20821 aactgagcta aaccaggtca aggagaacaa tcaaaccctt aagcgtttag cactacgcaa
    20881 agaagaatgg ctcaagacct accagtttct cttgatgaag gctgggcaaa cagaaccctt
    20941 gcaggccaat caccagttta caccggatgc tattgctttg cttttggtgt ttattgtgga
    21001 agagttgttt aaagaggagg aaattactat cctcgaaatg ggttctggga tgggaattct
    21061 aggcgctatt ttcttgacct cgcttactaa aaaggtggat tacttgggaa tggaagtgga
    21121 tgatttgctg attgatctgg cagctagcat ggcagatgta attggtttgc aggctggctt
    21181 tgtccaagga gatgccgttc gcccacaaat gctcaaagaa agcgatgtgg tcatcagtga
    21241 cttgcctgtc ggctattatc ctgatgatgc cgttgcgtcg cgccatcaag ttgcttctag
    21301 ccaagaacat acttacgccc atcacttgct catggaacaa gggcttaagt acctcaagtc
    21361 agacggatac gctatttttc tagctccgag tgatttgttg accagtcctc aaagtgattt
    21421 gttaaaagaa tggctgaaag aagaggcgag tctggttgct atgattagtc tgcctgaaaa
    21481 tctctttgct aatgccaaac aatctaagac tatttttatc ttacagaaga aaaatgaaat
    21541 agcagtagag ccttttgttt atccacttgc tagcttgcaa gatgcaagtg ttttaatgaa
    21601 atttaaagaa aattttcaaa aatggactca aggtactgaa atataaaata gattttgtta
    21661 taatagttga aaacgcttaa aaaggggtat catgttatga caaaaacaat tgcaatcaat
    21721 gcaggaagtt caagtttgaa atggcaatta tacttaatgc cagaagaaaa agtattggcg
    21781 aaaggtttga ttgaacgtat cggtttgaaa gattcaattt caactgtaaa atttgacggc
    21841 cgttctgaac aacaaatttt ggatattgaa aatcatatac aagccgttaa aattttattg
    21901 gatgacttga ttcgtttcga tattatcaag gcttatgacg agattacagg tgttggacat
    21961 cgtgttgttg ctggtggaga atatttcaaa gaatcaacag ttgttgaggg agatgtttta
    22021 gaaaaagttg aagagttgag tttgttggct cctctacaca acccggccaa tgcagcaggt
    22081 gttcgtgcct tcaaggaatt gttgccagac attaccagtg tagttgtttt tgatacttcc
    22141 ttccacacaa gtatgccaga gaaagcttat cgctaccctc taccaacaaa atattacaca
    22201 gaaaacaagg ttcgtaaata cggtgctcat ggtacaagtc accagtttgt agcaggagaa
    22261 gctgcaaaac tcttgggacg tccattagaa gacttgaagt taattacctg tcatattggt
    22321 aacggaggct caattacagc tgtgaaagcc ggcaaatctg tagacacttc tatggggttc
    22381 actcctcttg gtggtattat gatgggaacg cgtacagggg atattgatcc agctatcatt
    22441 ccttatttaa tgcaatatac agaggatttt aacacaccag aagatatcag tcgtgttctt
    22501 aaccgtgaat caggtctttt gggagtttct gctaattcta gcgatatgcg cgatatagaa
    22561 gcagctgtag cagaagggaa tcacgaggct agcttggctt atgaaatgta tgttgaccgt
    22621 atccaaaaac atatcggtca gtaccttgca gtgctaaatg gagcagatgc cattgttttc
    22681 acagcaggtg tcggtgaaaa tgcagagagt ttccgtcgtg atgtaatctc agggatttcg
    22741 tggtttggtt gtgatgttga tgatgaaaag aatgtctttg gcgttacagg agacatctca
    22801 acagaggcag ctaaaatccg tgtcttggtt attccaacag atgaagaatt agtcattgcc
    22861 cgtgacgttg aacgcttgaa aaaataagtg aaactaaaaa aatattcaat acaaggagtt
    22921 gggaaagtta tttttccagc ttctttttct gatgaaattg tccaaaacct tgctatgatt
    22981 ggcttttttg aaaaatatgg tataatagta gtaatttaat agatggagtt gagttttgaa
    23041 gaaaaacttt cgtgtaaaaa gagagaaaga ttttaaggcg attttcaagg aggggacaag
    23101 ttttgctaat cgcaaatttg tggtctacca attagaaaac cagaaaaacc attttcgagt
    23161 aggtctatca gttagcaaaa aactggggaa tgccgtcact agaaatcaaa ttaagcgacg
    23221 gattcggcat attatccaga atgcaaaagg gagtctggta gaagatgtcg actttgttgt
    23281 cattgctcga aaaggagtcg aaaccttggg atacgcagag atggagaaaa atctactcca
    23341 tgtattaaaa ttatcaaaga tttaccggga aggaaatggg agtgaaaaag aaactaaagt
    23401 tgactagttt gctaggactg tctctgttaa tcatgacagc ctgtgcgact aatggggtaa
    23461 ctagcgatat tacagccgaa tcggctgatt tttggagtaa attggtttac ttctttgcgg
    23521 aaatcattcg ctttttatcg tttgatatta gtatcggagt ggggattatt ctctttacgg
    23581 tcttgattcg tacagtcctc ttgccagtct ttcaggtgca aatggtggct tctaggaaaa
    23641 tgcaggaagc tcagccacgc attaaggcgc ttcgagaaca atatccaggt cgagatatgg
    23701 aaagcagaac caaactagag caggaaatgc gtaaagtatt taaagaaatg ggtgtcagac
    23761 agtcagactc tctttggccg attttgattc agatgccggt tattttggcc ctgttccaag
    23821 ccctatcaag agttgacttt ttaaagacag gtcatttctt atggattaac cttggtagtg
    23881 tggatacaac ccttgttctt ccgattttag cagcagtatt caccttttta agtacttggt
    23941 tgtccaacaa agctttgtct gaacgaaatg gcgctacgac tgcgatgatg tatgggattc
    24001 cagtcttgat ttttatcttt gcagtttatg cgccaggtgg agtcgcccta tactggacag
    24061 tgtctaatgc ttatcaagtc ttgcaaacct atttcttgaa taatccattc aagattatcg
    24121 cagagcgcga ggccgtagta caggcacaaa aagatttgga aaatagaaaa agaaaagcca
    24181 agaaaaaggc tcagaaaacg aaataaataa ggaggaatct ggtaatggta gtatttacag
    24241 gttcaactgt tgaagaagca atccagaaag gattgaaaga attagatatt ccaagaatga
    24301 aggctcatat caaagtcatt tctagggaga aaaaaggctt tcttggtcta tttggtaaaa
    24361 aaccagccca agtggatatt gaagcgatta gtgaaacgac tgttgtcaaa gcaaatcaac
    24421 aggtagtaaa aggcgttccg aaaaaaatca atgatttgaa cgagcctgtg aagacggtta
    24481 gtgaagaaac cgttgacctt ggtcatgtgg ttaatgctat taaaaaaata gaggaagaag
    24541 gtcaaggtat ttctgatgaa gtcaaggctg aaatcttaaa acatgaaaga catgccagca
    24601 ctatcttaga agaaactggt cacattgaga ttttaaatga acttcaaatc gaggaagcga
    24661 tgagggaaga agcaggcgct gatgaccttg aaactgagca agatcaaact gaaaatcaag
    24721 acttgaaaga gatgggcttg aaggtcgagc aaagttatga tattgcccag gtggctacgg
    24781 atgtgactgc ctatgttcaa gcgattgtgg atgacatgga tgttgaagct acactttcaa
    24841 atgattataa ccgtcgtagc atcaatctac aaattgacac caacgaacca ggtcgtatta
    24901 tcggctacca tggtaaagtc ttgaaggcct tgcaactgtt ggctcaaaat tatctttaca
    24961 accgctattc caaaaccttc tacgttacaa tcaatgtcaa tgattatgtc gaacaccgtg
    25021 cagaagtctt gcagacctat gcgcaaaaat tggcgaatcg tgttttggaa gaaggtcgca
    25081 gtcataaaac agatccaatg tcaaatagcg aacgcaagat tatccatcgt attatttcac
    25141 gtatggatgg cgtgactagt tactctgaag gtgatgagcc aaatcgctat gttgttgtag
    25201 atacagaata agtaaaatca gggttgacct gattttttgc tagttagagg aggttaaact
    25261 gatgttgaat aagataagag actatctaga cttttctggt ttgcagtacc gtagtcctga
    25321 taaagcggga gcagagcgag agaagatgct ggcgttccgc cacaaaggac aagaggcccg
    25381 aaaggctttt acagaactgg ccaaagcctt tcaagcaagc catccagaat ggcaactcca
    25441 acagactagt cagtggatga atcaggccca gcgtttgaga ccacattttt gggtttatct
    25501 acagagagac ggacaagtga cagaacctat gatggcctta cgtttgtatg ggacatctac
    25561 tgactttgga atttctttgg aagtcagttt catcgaacgt aagaaggatg agcaaacact
    25621 gggcaagcag gccaaagttt tagacattcc aaccgttaaa gggatttatt atctaaccta
    25681 ctctaatggt caaagtcaac ggtgggaggc gaatgaagaa aagcgtcgta ctttacgcga
    25741 gaaggtgaga agtcaagaag ttcgaaaagt tttagtgaag gtagatgttc ctatgacaga
    25801 aaattcgtct gaagaagaaa tcgtagaagg cttattgaag tcttattcta aaattcttcc
    25861 ctattatcta gctacgagaa aataagataa tttgtaaaac atcataaatc atacagtcca
    25921 agagtgaaca gtccgctgtg taattcttgg tctttttgtt tgcgctttcg cattatataa
    25981 taaacttaca aaaacaattc aaaaggagaa caattatgga agtcgtttca agtgttctaa
    26041 attggttttc tagcaatatt ttgcagaatc ccgcattttt cgtaggttta ttggtgttga
    26101 taggatatgc acttttgaaa aaacctgccc atgacgtttt ttcagggttt gttaaagcaa
    26161 cagtagggta tatgttgctt aacgtgggtg ctggtggttt ggttacaacc tttcgtccaa
    26221 tcttagcagc tcttaactac aaattccaaa ttggtgcagc ggttatcgac ccttattttg
    26281 gacttgctgc agcaaacaac aaaattgtag cagagtttcc agattttgtt ggaactgcaa
    26341 ctacagctct attgattggt tttggaataa atatcttgct cgtagctctt cgaaagatta
    26401 cgaaggtaag aaccctcttt attactggtc acatcatggt acaacaagct gcaacagtat
    26461 ctcttatggt tctattctta gtaccacaat tgcgcaatgc ttacggtaca gcagcgattg
    26521 gtatcatctg tggactttac tgggcagtta gttcaaatat gactgttgag gcaactcaac
    26581 gcttgactgg tggtggcgga tttgcgattg gtcaccaaca gcaatttgca atctggtttg
    26641 tagataaagt agcaggacgc tttggtaaga aagaagaaag tttagacaat cttaaattac
    26701 ctaagttcct ctcaatcttc cacgatacag ttgttgcatc tgctaccttg atgctcgtat
    26761 tcttcggagc cattctttta atcttgggtc cagacattat gtctaataaa gaagtcatca
    26821 cttcaggaac tctattcaat cctgctaaac aagatttctt tatgtacatt atccaaacag
    26881 cctttacctt ctcagtttac ttgttcgttt tgatgcaagg tgtccgaatg ttcgtatctg
    26941 agttgacaaa cgccttccaa ggtatttcaa acaaattgtt gccaggttca ttcccagcgg
    27001 ttgacgttgc agcttcttat ggatttggtt ctccaaatgc tgtcttgtca ggatttacct
    27061 ttggtttgat tggtcaattg attacaattg ttttgctcat cgtctttaaa aatccgattc
    27121 ttattattac aggatttgta ccagtgttct ttgacaatgc agccattgcg gtctacgctg
    27181 ataaacgcgg cggatggaaa gcggctgtta tcctttcctt tatatcaggt gtccttcaag
    27241 ttgctctagg agctctttgt gtggcccttc tcgatttggc atcttatggt ggctaccatg
    27301 gaaatatcga ctttgaattc ccatggcttg gatttggata tatcttcaaa taccttggta
    27361 ttgttggtta tgtacttgtg tgtctcttct ggcttgttat tcctcaactt caatttgcca
    27421 aagcaaaaga taaagagaaa tattacaacg gtgaagttca agaagaagct tagtatctag
    27481 aaaaggagaa ataaaatggt taaagtatta gcagcgtgcg gaaatggaat gggttcatca
    27541 atggttatca agatgaaggt tgaaaatgct ctccgtaagc ttaatcaaac agattttaca
    27601 gtcaattcat gcagtgtcgg tgaagctaaa ggtttagcag taggatatga cattgtaatc
    27661 gcttctcttc atttgattca agaattggaa gggcgaacta atgggaagtt aattgggctt
    27721 gataacttga tggatgataa agaaatcacc gaaaaactca gtcaagcact acagtaaaag
    27781 gttggagggg gctggacaga aactgagagt tatcgtttct gtccagcccc ctctttaaat
    27841 aaaggaggca gatatgaatt taaaacaagc tttaattgac aacgactcga tccgactagg
    27901 tttagaggct aacgattgga aagaagcagt caaggtagca gtagatccct tgattgaaag
    27961 tggggcaatt ttgccagagt attacgatgc tatcattgaa tcgactgaag agtatgggcc
    28021 ttactatatc ttgatgccag gtatggctat gccccacgct agacctgaag ctggtgtgca
    28081 aagtgatgcc ttttcattaa ttaccttaca aaatcctgtt gtattttcag atgggaaaga
    28141 ggtatctgtt ttgttggcac tagcagcaac aagttcaaaa attcacacaa gtgtagccat
    28201 tccacaaatt attgccctgt ttgaattaga agattctatt gcacgtttac aggcttgcca
    28261 gactaaagaa gatgtcttgg ctatgattga agaatctaag gatagccctt atctcgaagg
    28321 attggatttg gaaagttaga aagaggaata aagaaatgac aaaaagaata cctaatttac
    28381 aagttgcatt agaccattca gacttgcaag gagcgattaa agcagctgtt tctgttggtc
    28441 aggaagtaga tattatcgaa gctggaactg tttgcttgct tcaagttgga agtgaactgg
    28501 ctgaagtctt gcgtagcctt ttcccagata agattattgt ggcagacaca aaatgtgctg
    28561 atgctggtgg aacagttgct aaaaataatg cggttcgtgg agcagactgg atgacttgta
    28621 tctgttgtgc aaccatccct actatggaag cagctctaaa ggctatcaag actgaacgag
    28681 gagaacgagg cgaaatccag atcgagcttt atggcgattg gacttttgaa caagctcagc
    28741 tttggctaga tgcaggtatc tcacaagcta tttatcacca atctcgtgat gctcttcttg
    28801 ctggtgaaac ttggggtgaa aaagacctta ataaggttaa aaaactcatt gacatgggct
    28861 tccgtgtatc tgtaacaggt ggtctagatg tagatactct caaactcttt gaaggtgttg
    28921 atgtctttac ctttatcgca ggtcgtggaa ttacagaggc tgtggatcca gcaggagcag
    28981 cgcgtgcctt caaggatgaa atcaaacgaa tttgggggta aatcatggta cgtccaattg
    29041 gaatttatga aaaggcaacc ccaacacact ttacttggct agaacgttta aattttgcca
    29101 aggagttagg ctttgatttt atcgagatgt ctattgacga acgtgacgag cgtttagcaa
    29161 gacttgactg gagtaaggaa gaacgcttgg aagttgtcaa agaaatctat gaaactggtg
    29221 ttcgtattcc ttctatctgt ttttcaggcc atcgtcgcta cccattggga tcaaaagatt
    29281 cagttctaga ggaaaaatct ctagaactca tgaaaaaatg tatcgaatta gctcaagact
    29341 tgggagttcg tacgattcaa ttagctggtt acgatgttta ctatgaggaa aagtcacccc
    29401 agacacgcca acgttttatc aaaaatttga gaaaatcctg tgactgggct gaagaagctc
    29461 aggtggtact tgctattgaa attatggatg atcctttcat cagtagcatc gaaaaatatt
    29521 tggctataga aaaagagatt gactctccct tcctctttgt atatccagat attggtaatg
    29581 tgtctgcatg gcataatgat atctatagtg agttttatct tggtcatcat gccatcgcag
    29641 ctctccatct caaggatact tatgcagtga cagaaagttc aaagggccag ttccgagatg
    29701 tacctttcgg gcaaggttgt gtcaaatggg aagaagcttt cgatatttta aaggaaacca
    29761 attataatgg acctttccta atcgaaatgt ggtctgaaaa ttgtgaaaca gtagaagaaa
    29821 cacgcgcagc cattcaagag gcgcaagctt ttctctatcc actcattaag aaagcaggtt
    29881 tgatgtaaga tgaatcaagt aatcaatgct atgcgtaaac gagtctgtga tgccaatcaa
    29941 tcattgccaa aacatggact tgtcaaattt acctggggga atgtatctga agttaatcgc
    30001 gaactcggtg tcattgttat caaaccatca ggcgtggatt atgacgaatt gacacctgaa
    30061 aacatggtag tgactgatct agatggtaag atcctagaag gggatttaag accatcttcc
    30121 gacctcccaa ctcatgtgca attatataag gcttggtcag aaattggtag tgtggttcac
    30181 acccattcga cagaagctgt tggttgggct caggcaggtc gtgatattcc tttctacgga
    30241 acaacccatg cagattattt ctacggttca atcccttgcg cccgtagttt gaccaaggac
    30301 gaagtagaag tggcctatga aaaagatact ggcctggtta tcgtagaaga gtttgaacat
    30361 cgcggactta acccggttga agtaccagga attgttgtac gcaatcacgg tccattcacc
    30421 tggggcaaaa atccagagaa tgctgtttat cactctgtcg tactagagga agtatcaaag
    30481 atgaatcgct ttacagaaca aatcaatcca agagttggac ctgctcccca gtacatacta
    30541 gaaaaacact accaacgtaa acatggacca aatgcttatt atggtcaaaa gtaagaacga
    30601 tgaaggagga gaaaaagata aatttagctc ctctttttac atttgatttt tattgagagt
    30661 aaagttggaa ttgaagtaat tttaaaagat tttttagaaa tagcgcttga tatatatatg
    30721 gtaaaataaa aagaattgct gtgatatcaa tagatttggg ggatttttta atatggtact
    30781 ggataaggca agttgtgatt tgcttcaata tttgatggat caagaaacgt ccaaaacgat
    30841 tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa atttattatc acattgacaa
    30901 aatcaatgct gctctgggtg acgaggcgct tcacatcatt agtattccac gaattggtat
    30961 tcacttaacg gaagagcaga gagatgcttg ttgtaaacta ttatcggaag tagattcgta
    31021 cgattatatc atgagtgcgc atgaacgtat gatgataatg ttactatgga taggtatttc
    31081 taaagaacgt attacgattg aaaaattgat agagttaaca gaggtatcta ggaatactgt
    31141 tctcaatgat ttgaatagta ttcgttatca actaactttg gaacaatatc aggtgatctt
    31201 gcaagtgagc aagtcacagg gataccacct tcatgcccac cctcttaata aaattcagta
    31261 tcttcaatcg cttctatatc atatttttat ggaagaaaat gccacttttg tatctatttt
    31321 agaagataag atgaaagaga ggttagatga tgagtgtttg ctttctgttg aaatgaacca
    31381 attttttaag gaacaggttc ctttagttga acaagattta gggaagaaaa taaaccatca
    31441 tgaaataact tttatgttgc aggttctacc ttatttgctg ttaagctgtc ataatgttga
    31501 acagtatcaa gaaagacatc aggatataga gaaagaattt tctttgataa gaaaaagaat
    31561 agagtatcag gtgtctaaga aattaggaga acggttgttt caaaagtttg aaatttcttt
    31621 gtcaggactt gaagtttctc ttgtagctgt tctcctcctc tcctatcgta aagatttgga
    31681 tattcatgca gaaagtgatg attttcggca attaaaactt gctttagaag aatttatctg
    31741 gtattttgaa tcacaaatcc gaatggagat tgagaacaag gatgatttgt tacgaaattt
    31801 gatgatccac tgtaaagcct tgttatttag aaagacttac ggtatttttt ctaaaaatcc
    31861 tctaacaaaa caaattcgat ccaagtatgg agaattattt ttagtcacta gaaaatctgc
    31921 ggaaatttta gaaggagcat ggtttattcg gctaacagac gatgatattg cctatttgac
    31981 gattcatatt ggaggatttt taaagtatac accatcgtct caaaaaaata tgaaaaaagt
    32041 ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt ttgctgaaac aatgcaaact
    32101 ttattttcca aatgagcaaa ttgacactgt atttacaaca gaacaattta agagtgtgga
    32161 agatattgca caagttgatg tagtgattac tactaatgat gatttggata gcagatttcc
    32221 gattttaagg gttaatccta tccttgaagc agaagatatt ttgaaaatgc tagactatct
    32281 taaacacaat atatttcgta ataagagcaa aagtttcagt gaaaatcttt ctagtcttat
    32341 ttcgtcttat attgtagaca gcaagttggc tagtaagttc caagaagagg ttcaaacact
    32401 tataaataaa gaaatagtag ttcaagcttt tttggaagat atttgaagga cagtccaatg
    32461 atgaacacaa acctgtgttt ttcttggtct tttttagtgt tttgaagggt ggtatactaa
    32521 tctcaaagat aacaattata tccaaaggag gcaacatatg ccaaacgtca aagaaattac
    32581 aagagagtca tggattttag ccactttccc agagtgggga acatggttga acgaagaaat
    32641 cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg tggctaggca actgtggtac
    32701 ttggattaag acaccagctg gtgctaacgt tgtcatggac ctttggtcaa accgtggaaa
    32761 atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa atggcaaata tggcaggtgt
    32821 tcgtaagttg caaccaaact tgcgtgttca gccaatggtt atcgatccat ttgctatcaa
    32881 cgaactagac tattacttag tttcacactt ccacagtgat catatcgacc catacacagc
    32941 tgcagcaatt ctcaacaatc ctaagttaga gcatgttaag tttatcggtc cttaccactg
    33001 tggacgaatc tgggaaggat ggggtgttcc aaaagaacgt atcatcgttg ttaaaccagg
    33061 tgacactatc gaattaaaag atatgaagat tcatgcagta gaatcatttg accgtacttg
    33121 cttggtaact ctcccagtga acggtgctga tgagacaggc ggtgaacttg ctggcttggc
    33181 tgttacagat gaagaaatgg ctcaaaaggc tgttaactat atctttgaaa caccaggtgg
    33241 aaccatctat catggtgcag attctcactt ctcaaactat tttgcaaaac atggtaaaga
    33301 ctttaaaatt gatgttgctt tgaataacta tggtgaaaat ccggtaggta tccaagacaa
    33361 aatgacatct atcgaccttc ttcgtatggc agaaaatctg cgtaccaaag tcattatccc
    33421 agttcactat gatatctggt ctaacttcat ggcttctact aatgagattc tagaactttg
    33481 gaaaatgcga aaagatcgct tgcaatacga tttccatcca tttatctggg aagttggcgg
    33541 taagtacact tatcctcaag atcaacactt agtagaatac catcatccac gtggttttga
    33601 tgattgtttt gaacaagact ctaacattca atttaaagct ttgctataat ataaaaatat
    33661 tctttggagg ttatccgtat gttgcatgat acggataatt ttcatataat agtaaaatag
    33721 aatgtgtgat tcaataatca cctcaaatag aaaggaaatt ctatgtcaaa tctatctgtt
    33781 aatgcaattc gttttctagg tattgacgcc attaataaag ccaactcagg tcatccaggt
    33841 gtggttatgg gagcggctcc gatggcttac agcctcttta caaaacaact tcatatcaat
    33901 ccagctcaac caaactggat taaccgcgac cgctttattc tttcagcagg tcatggctca
    33961 atgctccttt atgctcttct tcacctttct ggttttgaag atgtcagcat ggatgagatt
    34021 aagagcttcc gtcaatgggg ttcaaaaaca ccaggtcacc cagaatttgg tcatacggca
    34081 gggattgatg ctacgacagg tcctctaggg caagggattt caactgctac tggttttgcc
    34141 caagcagaac gtttcttggc agccaaatat aaccgtgaag gctacaatat ctttgaccac
    34201 tatacttacg ttatctgtgg agacggagac ttgatggaag gtgtctcaag cgaggcagct
    34261 tcatacgcag gcttgcaaaa acttgataag ttggttgttc tttatgattc aaatgatatc
    34321 aacttggatg gtgagacaaa ggattccttt acagaaagtg ttcgtgaccg ttacaatgcc
    34381 tacggttggc atactgcctt ggttgaaaat ggaacagact tggaagccat ccatgctgct
    34441 atcgaaacag caaaagcttc aggcaagcca tctttgattg aagtgaagac ggttattgga
    34501 tacggttctc caaacaaaca aggaactaat gctgtacacg gcgcccctct tggagcagat
    34561 gaaactgcat caactcgcca agccctcggt tgggactacg aaccatttga aattccagaa
    34621 caagtatatg ctgatttcaa agaacatgtt gcagaccgtg gcgcatcagc ttatcaagct
    34681 tggactaaat tagttgcaga ttataaagaa gctcatccag aactggctgc agaagtagag
    34741 gccatcatcg acggacgtga tccagtcgaa gtgactccag cagacttccc agctttagaa
    34801 aatggttttt ctcaagcaac tcgtaattca agtcaagatg ccttgaatgt tgtggcagct
    34861 aaattaccaa ccttcctagg tggatcagct gaccttgctc actcaaacat gacttatatc
    34921 aagacggatg gacttcaaga cgataccaat cgcttgaatc gtaacattca gtttggtgtt
    34981 cgtgaatttg caatgggaac aatcttgaac gggatggccc ttcatggtgg acttcgtgta
    35041 tacggtggaa ctttcttcgt cttctctgac tatgtgaagg cagctgtccg cttgtcagcc
    35101 ttacaaggac ttcctgtgac ttatgtcttt acccatgatt caatcgcagt tggggaagat
    35161 ggtccgactc acgaaccagt tgagcattta gcaggtcttc gtgctatgcc aaatctaaat
    35221 gttttccgtc cagcagatgc gcgtgaaact caagcagctt ggtaccttgc agtgacaagt
    35281 gagaaaacac caactgccct tgtcttgaca cgtcaaaact tgactgttga agatggaaca
    35341 gacttcgaca aggttgctaa aggtgcttat gttgtatatg aaaatgcagc cgactttgat
    35401 accatcttga ttgcgacagg ttcagaggtt aatcttgctg tctcagctgc taaagaattg
    35461 gctagtcaag gcgaaaaaat ccgcgtagtc agcatgccat ctacagatgt ctttgataaa
    35521 caagatgcag cttacaagga agaaattctt ccaaatgcag tccgccgtcg tgttgcagtc
    35581 gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc tcgatggtgc cgttctaggt
    35641 attgatacct tcggagcctc tgccccagca ccaaaagtat tggcagaata tggctttact
    35701 gtagaaaatc ttgtaaaaat tgttcgaaac ttgaaataat cctaaaaatc agggcgtaag
    35761 ctctggtttt tcttaccaga aaagtaaggt acaatcttgt aaaagtagct gaaatttgat
    35821 atagtagtcc tatgtaaaag acaaaggaga aaacaatgaa tccaaatatt acttttttaa
    35881 tcatgcttgt aggtatgatg gccttgatgt tctttatgca acgttctcaa aagaaacaag
    35941 ctcaaaagcg tatggaaagc ttaaataaac tacaaaaagg ctatgaagtg attacaatcg
    36001 gtggacttta tggaacagtc gatgaagtag atacggagaa gggaacaata gttcttgacg
    36061 tagatggagt ttacttgact tttgaactag ctgctatcaa gacagtatta ccgctgaaag
    36121 aaacagcttc actagaaggc gcaattgaaa aataagacgg gatcacgaac tcccgttttt
    36181 ctataaaaga aaggaaatgg gatgaaaaaa ttagtctttg tctgtctggg aaatatttgc
    36241 cgtagcccta tggccgagtt tgttatgaaa tcaatgacag ataactacga aatccaaagt
    36301 cgagcaactt cctcttggga acatggcaat ccgattcata aggggactca gggaattttt
    36361 caacagtatg agattcctta tgacaagaac aagacatcgc ttcagattag taaggaagat
    36421 tttgaagcct ttgattatat tatcggaatg gacgcttcaa atatttctga cttacgtcag
    36481 atgtgtccag tagactgtca agataagatt tactcatttt catctgaaag tgttccagac
    36541 ccttggtata caggagattt tgaagaaacc tatcgacgtg ttcaagaggg ctgtcaagct
    36601 tggttagaac gtttagaaaa ggagagttaa ggtggaaaat cttacgaatt tttacgaaaa
    36661 gtatcgtgtc tatctgactc gtccacgttt agagcttttg gcagtagtta ccattgtttt
    36721 ctgtgctgta ctcgtctttt ttctaaatat tccaggaaaa ggtgtcttaa aactcgataa
    36781 tggaacgatt gtttatgatg gcagtcttgt ccgtggtaaa atgaatggtc aaggtaccat
    36841 taccttccaa aatggagacc aatatacagg tggcttcaac aatggagcct tcaacggaaa
    36901 aggtaccttt caatctaaag aaggctggac ctacgaaggt gattttgtaa atggtcaggc
    36961 tgaaggaaaa gggaaactaa caacagaaca agaagtcgtt tatgaaggaa cttttaaaca
    37021 aggcgttttt caacaaaaat aaagcctcct tatccaaagg aggtattatt agaaccacaa
    37081 ggtaagcgct tacctgtaaa tccctttctt tccaaatccc tttctttcca aatccctctt
    37141 ccaagcaagt ttgtgaaata aaaaatattt gaaataaatt tcacaaactt caaagataaa
    37201 acctgataag aaaagaaaat gagaaaagtt tcacaagagt ttaaaaattc tttgtgaaat
    37261 gtttatgaaa ctgtttacaa agttgaaata atgcgttata ataaacttgt gaaaaaatta
    37321 acaaaggata tcgttccttg aaagctatgg aggaaaatat ggctgataaa aaaactgtga
    37381 caccagagga aaagaaactc gttgctgaaa aacacgtaga tgagttggtt caaaaagctc
    37441 tagttgccct tgaagaaatg cgtaaattgg atcaagagca agttgactac atcgttgcca
    37501 aagcatcagt agcagctttg gatgcccacg gagaattggc tttacatgcc tttgaagaaa
    37561 caggacgtgg tgtatttgaa gacaaagcaa ctaagaactt gtttgcctgt gaacacgtag
    37621 taaacaacat gcgccacact aagacagttg gcgttatcga agaagacgat gtaacaggat
    37681 tgactcttat tgctgaacca gttggtgttg tttgtggtat tactccaaca acaaacccaa
    37741 catcaacagc aattttcaaa tcattgattt cattgaagac acgtaaccca atcgtctttg
    37801 ccttccatcc atcagcacaa gaatcatctg ctcatgcagc tcgtatcgtc cgcgatgcag
    37861 ctatcgcagc tggtgctcct gaaaactgtg tgcaatggat tactcaacca tctatggaag
    37921 caacaagtgc ccttatgaac cacgaagggg ttgcgacaat ccttgcaaca ggtggtaatg
    37981 ccatggttaa ggcggcttat tcatgtggta aaccagctct tggggtaggt gccggaaacg
    38041 ttccagctta tgttgaaaaa tcagcaaaca ttcgtcaagc agcacacgat atcgtcatgt
    38101 ctaaatcatt tgataacggt atggtctgtg catctgaaca agcagttatc attgataaag
    38161 aaatttacga tgaatttgta gcagagttca aatcttacca cacttacttt gtaaacaaaa
    38221 aagaaaaagc tcttcttgaa gagttctgct tcggcgtcaa agcaaacagc aaaaactgtg
    38281 ctggtgcaaa attgaacgct gacatcgttg gtaaaccagc aacttggatt gcagaacaag
    38341 caggatttac agttccagaa ggaacaaaca ttcttgctgc agaatgtaaa gaagttggcg
    38401 aaaatgagcc attgactcgt gaaaaattgt caccagttat tgcagttttg aaatctgaaa
    38461 gccgtgaaga tggtattact aaggctcgtc aaatggttga atttaacggt cttggacact
    38521 cagcagctat ccacacagct gacgaagaat tgactaaaga atttggtaaa gctgttaaag
    38581 ctattcgtgt tatctgtaac tcaccttcta cttttggtgg tatcggggac gtttacaatg
    38641 ccttcttgcc atcattgaca cttggatgtg gttcttacgg acgcaactca gttggggata
    38701 acgttagtgc cattaacctc ttgaatatca aaaaagtcgg aagacggaga aataacatgc
    38761 aatggatgaa acttccttca aaaacatact ttgaacgtga ttcaattcaa taccttcaaa
    38821 aatgtcgtga cgttgaacgt gtcatgatcg ttactgacca tgccatggta gagcttggtt
    38881 tccttgatcg tatcatcgaa caactggacc ttcgtcgcaa taaggttgtt taccaaatct
    38941 ttgcggatgt agaaccggat ccagatatca caactgtaaa ccgtggtact gagattatgc
    39001 gtgccttcaa accagatacc atcatcgcac tcggtggtgg gtctccaatg gatgctgcca
    39061 aagtaatgtg gctcttctac gagcaaccag aagtggactt ccgtgacctt gtccaaaaat
    39121 tcatggatat ccgtaaacgt gccttcaagt tcccattgct tggtaagaag actaaattca
    39181 tcgcgattcc aactacatct ggtacaggat ctgaagtaac accatttgcc gttatctctg
    39241 ataaagcaaa caaccgtaaa tacccaatcg ctgactactc attgacacca actgtggcaa
    39301 tcgtagatcc tgctttggta ttgacagttc caggatttgt tgctgctgat actggtatgg
    39361 acgtattgac tcacgcgaca gaagcatacg tatcacaaat ggctagtgac tacactgatg
    39421 gtttagcact tcaagccatt aaattggtct ttgaaaatct cgaaagctca gttaagaatg
    39481 cagacttcca ctcacgtgag aaaatgcata acgcttcaac aatcgctggt atggcctttg
    39541 ccaatgcctt cctaggtatt tctcactcaa tggcccataa gattggtgcg caattccaca
    39601 caatccacgg tcgtacaaat gctatcttgc ttccatacgt tatccgttac aacggtacac
    39661 gtccagctaa gacagcaaca tggcctaagt acaactacta ccgtgcagat gaaaaatacc
    39721 aagatatcgc acgcatgctt ggacttccag cttctactcc agaagaaggg gttgaatctt
    39781 acgcaaaagc tgtctacgaa ctcggtgaac gtattgggat ccaaatgaat tttagagacc
    39841 aaggaattga cgaaaaagaa tggaaagaac attctcgtga attagccttc ctggcttatg
    39901 aagaccaatg ttcaccagct aacccacgtc ttccaatggt agaccatatg caagaaatca
    39961 tcgaagatgc atactatggc tacaaagaaa gaccaggacg ccgtaaataa ttgtttatca
    40021 gtctagaagc aagacaaaaa ctcaatttga gggaaagatc cagtaatttt tctatgataa
    40081 aaggcatcct atcaaggttt ttgaacacct gataggatgc ctttttatga tattgaggcc
    40141 tttttgccct ttttgaaaaa ctagaataga aacaaaatat ataatagatt gaaactagag
    40201 tagtacacat ctgcttctaa aacattgtta gaattcgatt tgactgtcct gatcaatttg
    40261 tcctgttctt atttcatttt aatatataaa aaatatagta tagtagactg aatctaaaat
//
LOCUS       DAVLHB010000015        37436 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLHB010000015 DAVLHB010000000
VERSION     DAVLHB010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37436
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.015"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(79..1746)
                     /locus_tag="VXE36_000896"
     CDS             complement(79..1746)
                     /locus_tag="VXE36_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0779221.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(1749..2114)
                     /locus_tag="VXE36_000897"
     CDS             complement(1749..2114)
                     /locus_tag="VXE36_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0779222.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(2271..2459)
                     /locus_tag="VXE36_000898"
     CDS             complement(2271..2459)
                     /locus_tag="VXE36_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0779223.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(2575..2751)
                     /locus_tag="VXE36_000899"
     CDS             complement(2575..2751)
                     /locus_tag="VXE36_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0779224.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(2862..3059)
                     /locus_tag="VXE36_000900"
     CDS             complement(2862..3059)
                     /locus_tag="VXE36_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0779225.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(3314..4858)
                     /locus_tag="VXE36_000901"
     CDS             complement(3314..4858)
                     /locus_tag="VXE36_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0779226.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            5071..5373
                     /gene="gatC"
                     /locus_tag="VXE36_000902"
     CDS             5071..5373
                     /gene="gatC"
                     /locus_tag="VXE36_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0779227.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTNRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            5373..6839
                     /gene="gatA"
                     /locus_tag="VXE36_000903"
     CDS             5373..6839
                     /gene="gatA"
                     /locus_tag="VXE36_000903"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0779228.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPATFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            6839..8281
                     /gene="gatB"
                     /locus_tag="VXE36_000904"
     CDS             6839..8281
                     /gene="gatB"
                     /locus_tag="VXE36_000904"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0779229.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKETKGQANPQVALKLLAQELAKLKEN"
     gene            8410..8970
                     /gene="efp"
                     /locus_tag="VXE36_000905"
     CDS             8410..8970
                     /gene="efp"
                     /locus_tag="VXE36_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0779230.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            8992..9381
                     /locus_tag="VXE36_000906"
     CDS             8992..9381
                     /locus_tag="VXE36_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0779231.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            9374..9796
                     /gene="nusB"
                     /locus_tag="VXE36_000907"
     CDS             9374..9796
                     /gene="nusB"
                     /locus_tag="VXE36_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0779232.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAHTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(9845..10072)
                     /locus_tag="VXE36_000908"
     CDS             complement(9845..10072)
                     /locus_tag="VXE36_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0779233.1"
                     /translation="MLSGLIFGLSHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRL
                     TILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(10563..10748)
                     /gene="briC"
                     /locus_tag="VXE36_000909"
     CDS             complement(10563..10748)
                     /gene="briC"
                     /locus_tag="VXE36_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0779234.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(10907..11674)
                     /locus_tag="VXE36_000910"
     CDS             complement(10907..11674)
                     /locus_tag="VXE36_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0779235.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(11671..12537)
                     /locus_tag="VXE36_000911"
     CDS             complement(11671..12537)
                     /locus_tag="VXE36_000911"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0779236.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(12574..13941)
                     /gene="accC"
                     /locus_tag="VXE36_000912"
     CDS             complement(12574..13941)
                     /gene="accC"
                     /locus_tag="VXE36_000912"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0779237.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(13953..14375)
                     /gene="fabZ"
                     /locus_tag="VXE36_000913"
     CDS             complement(13953..14375)
                     /gene="fabZ"
                     /locus_tag="VXE36_000913"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0779238.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(14372..14857)
                     /locus_tag="VXE36_000914"
     CDS             complement(14372..14857)
                     /locus_tag="VXE36_000914"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0779239.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(14860..16095)
                     /gene="fabF"
                     /locus_tag="VXE36_000915"
     CDS             complement(14860..16095)
                     /gene="fabF"
                     /locus_tag="VXE36_000915"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0779240.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(16117..16848)
                     /gene="fabG"
                     /locus_tag="VXE36_000916"
     CDS             complement(16117..16848)
                     /gene="fabG"
                     /locus_tag="VXE36_000916"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0779241.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQVGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(16882..17802)
                     /gene="fabD"
                     /locus_tag="VXE36_000917"
     CDS             complement(16882..17802)
                     /gene="fabD"
                     /locus_tag="VXE36_000917"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0779242.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(17795..18769)
                     /gene="fabK"
                     /locus_tag="VXE36_000918"
     CDS             complement(17795..18769)
                     /gene="fabK"
                     /locus_tag="VXE36_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0779243.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(18888..19112)
                     /locus_tag="VXE36_000919"
     CDS             complement(18888..19112)
                     /locus_tag="VXE36_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0779244.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQEK"
     gene            complement(19172..20146)
                     /locus_tag="VXE36_000920"
     CDS             complement(19172..20146)
                     /locus_tag="VXE36_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0779245.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(20146..20580)
                     /locus_tag="VXE36_000921"
     CDS             complement(20146..20580)
                     /locus_tag="VXE36_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0779246.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(20674..21459)
                     /locus_tag="VXE36_000922"
     CDS             complement(20674..21459)
                     /locus_tag="VXE36_000922"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0779247.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            21829..23193
                     /locus_tag="VXE36_000923"
     CDS             21829..23193
                     /locus_tag="VXE36_000923"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0779248.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            23196..23567
                     /locus_tag="VXE36_000924"
     CDS             23196..23567
                     /locus_tag="VXE36_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0779249.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            23781..25055
                     /gene="serS"
                     /locus_tag="VXE36_000925"
     CDS             23781..25055
                     /gene="serS"
                     /locus_tag="VXE36_000925"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0779250.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(25080..25979)
                     /locus_tag="VXE36_000926"
     CDS             complement(25080..25979)
                     /locus_tag="VXE36_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0779251.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(26089..26637)
                     /locus_tag="VXE36_000927"
     CDS             complement(26089..26637)
                     /locus_tag="VXE36_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0779252.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(26855..28177)
                     /locus_tag="VXE36_000928"
     CDS             complement(26855..28177)
                     /locus_tag="VXE36_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0779253.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSYFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(28268..28356)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(28520..30856)
                     /locus_tag="VXE36_000929"
     CDS             complement(28520..30856)
                     /locus_tag="VXE36_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0779254.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQVLFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNVVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(30960..31508)
                     /locus_tag="VXE36_000930"
     CDS             complement(30960..31508)
                     /locus_tag="VXE36_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0779255.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(31505..31807)
                     /gene="zapA"
                     /locus_tag="VXE36_000931"
     CDS             complement(31505..31807)
                     /gene="zapA"
                     /locus_tag="VXE36_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0779256.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            31894..32766
                     /locus_tag="VXE36_000932"
     CDS             31894..32766
                     /locus_tag="VXE36_000932"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0779257.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            32778..33392
                     /gene="lepB"
                     /locus_tag="VXE36_000933"
     CDS             32778..33392
                     /gene="lepB"
                     /locus_tag="VXE36_000933"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0779258.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            33626..35992
                     /locus_tag="VXE36_000934"
     CDS             33626..35992
                     /locus_tag="VXE36_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0779259.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEVPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(36040..37323)
                     /locus_tag="VXE36_000935"
     CDS             complement(36040..37323)
                     /locus_tag="VXE36_000935"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0779260.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEKSLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        10860 a         8622 c         7255 g        10699 t
ORIGIN      
        1 ttttgttttt attaaaaaga taccgatttc atttactaaa aaagaaaaaa gaactgattt
       61 ctcagtcctt cattaatctt attccacact aaataggtat gggtaaacag gttgttgacc
      121 ttggtgaatc tcgacttcaa cgtcttcgaa ttcttctacg atttcttgag cgatttcatt
      181 ggcaagttct tcgcttccgt cttcaccgac atagaaggtt acgatttcac tgtcttcatc
      241 caacatatgt ttcaaggttt cagtcaatgt ttggtgcata tcagggtttg acacaagaat
      301 ttttccatcc accataccta gattatcgtt ttcatggatt tctaagccat cgatcgttgt
      361 atcacgcacg gctgttgtga cgcttccgct aacgacatcg ctaagagcag ctgtcatacg
      421 ctcttggttt tcttcaatgg acttgcttgg atcaaaggca agaagacttg tcataccttg
      481 aggaagagtg cgagcctcta ccactactgc tggttgctcc aaaacttctg ccgcagattg
      541 agctgccatg aagatgttct tgttatttgg caagaagatg atgttacggg cattgacctg
      601 ttcaacagcc ttgataaagt cttctgttga agggttcatg gtttgaccgc cttcgataac
      661 atagtccacg ccttgagaac agaagatatc tgctagacct ttaccagcca ccacagcaat
      721 caaagcatac tctttttctt cagccgactt gataacttga gtagcttctt tctcaacctg
      781 tgcttcgtgt tggttacgca tattgtcaac ttttaccttg accaagctac catatttgag
      841 accttcttgc ataacaagtc ctggatcttc tgtatgaaca tggactttga caatttcatc
      901 atcgttaaca acgaggagag aatccccaag ctcatccaag tagttacgga attcatcgta
      961 gtcaaaatct ttagcatagg ttggaccttg cttaagagct accatgattt cagtacagta
     1021 accaaacgtg atgtcctcag ttgctacgtg accagctaca gacttatgat gctctacatt
     1081 gatcatctca ctcatgttgg caggagtcgc tacaaagtcc tcagatgcaa tatattcgcc
     1141 agtaagggct gaaaggaaac cttcgtagat gaagaccaat ccttgaccac ctgagtccac
     1201 aacgccaact tctttcaata ctggaagcat gtctggtgtt ttagctagag ctgttttagc
     1261 accttccaag gctgcgcgca tgacttcaac agtgtcatct gtttgctcag cttttttctt
     1321 agcaccgata gcagctccac gagaaactgt caaaatcgtt ccttcaacag gtttcatcac
     1381 tgccttatag gcaacttcca cacctgattg gaaggccaga gccaagtctt gacctgttaa
     1441 ctcgtcttta tccttgatag cttgggaaaa tccacggaaa agctgagacg taatcactcc
     1501 tgagttccca cgcgcaccca tcaaaagccc tttggcaaga atgctcgcta cttctccaac
     1561 tgtagaagct ggcttgtctg caacttcttt agcaccattt tcaatggtca ttcccatatt
     1621 tgtcccagta tctccatctg gaactggaaa gacgtttaat gaattgacat attcagcttg
     1681 cttattcaag cgagttgatg cagcctgcac catttcttga aataagctag tagtaatttt
     1741 tgacacggtt attctcctac aactttgata ttttgaatgt agacatttac agtctgagca
     1801 gtaattccaa gctggttttc caagctaaag gcaacacgct cttgaatgtt ttttgacact
     1861 tcactaatct ttgttccgta gcttaacacg gtatatacat caactgcaat actgccatct
     1921 tcggctgcct ttacgacgac acctttagaa taattttcct tacctagcag ggcttggaaa
     1981 ttatctttga gggcattttt actagccata ccgaccacac caaaaatctc agttgctgct
     2041 ccacctacga cggttgcaat cacttcatct gttagttcga tttgaccatc ttttgtatta
     2101 atttttacag tcatcctttt tacctcaact agttgatact ctattttatc atatttcagc
     2161 ccaagtgtaa aagcagaatg atgtatcagc ggatatttac tctatttttc aaacgatgtt
     2221 atacccacaa taaaagaaaa aagaccctaa ggtctccttt gcttttatta ttaaacgcgt
     2281 tcaactttac ctgatttcaa agcacgagct gaagcccaaa cttttttagg tttaccatcg
     2341 ataagaacag taactttttg aaggtttggt tttacggcac gttttgtttg gttcatcgcg
     2401 tgtgaacggt tgtttcctga tacagtctta cgacctgtaa agtaacatac tttagccatt
     2461 gtgttttcct cctattagat ctaatatagc ggatgtgcta gcaccacata ccgtactatg
     2521 ttatcacact ttcttgtttt ttgcaaggga attggaagat tttttatttg tgtcttaaat
     2581 caggtcttgc gtgacatttt ctgctctcca catgccatcg ttgattaaca gaacaccaga
     2641 attaaaatta tgtgtataaa aatcatctct aactgcagct aagggtatag ccgtcaagtc
     2701 caaatcccac agctcatcta tcgattttct tacaacaata tctgaatcca aatacagtac
     2761 acgagactcg cttacatact ttggaataaa atacctaaaa aagccgcata tgaaagtccc
     2821 tcaaagggga gacgataacc tttcagaata ttactgtcaa tctaaacatt cacaatctca
     2881 ctattcaaag tctctagtct tttttccatc aattggaacc attctcgcgg aaggtcatca
     2941 ttaaaaacat aaaacttaag attataatga tgaacacaaa gagattttat tgttgtttca
     3001 actttatcca tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact
     3061 ttttatctca tttcttttta ttcccatcat atgtttctac gtaaccatta ttttcgccta
     3121 ttcgttcgta aaaccatacc agtggagatt ttagatgaag tcccattacg gtttacaatt
     3181 tttacattac gacacggagt tttacaaatc gatttcattt gccaaacgta gttagtgagg
     3241 cagttagcta gttcgccaaa tagcgactag cgtccaacaa tttggaactt tagttccaat
     3301 tgttggtact gagtcacatc ttctcctcta actctacgtc tggatacttg tcagcaaacc
     3361 agcggagggc aaagtcattt tcaaagagaa agactggttg gtcaaaacgg tctttggcta
     3421 agatattgcg acttgacgac atccgttcat ccaagtcctc aggcttgatc caacgaacgg
     3481 tctttttacc cattgggttc ataactactt ctgcattgta ctcgccttcc atgcggtgtt
     3541 taaagacttc aaactggagt tgacctacag cgcctagcat gtactcacct gtttggtaat
     3601 tcttataaag ctgaacggct ccttcttgca ccaattgctc aatccccttg tggaaggatt
     3661 tttgcttcat aacattctta gcagaaactt tcatgaaaat ttcaggagta aaggttggca
     3721 gtggttcaaa ttcaaacttg tttttaccaa ctgtcaaggt atccccaact tgataagtac
     3781 cggtatcgta aaccccgata atatcacctg ccacggcatt gatcacattc tcacgacttt
     3841 ccgccataaa ctgagtaaca ttagacagtt tagccccctt accagtacga gggagattga
     3901 cactcatgcc gcgctcaaat tcgccagata cgatacggac aaaggcaata cggtcacggt
     3961 gacgagggtc catgttggct tggattttaa agacaaagcc tgagaaatcc ttgtcataag
     4021 gatccacaat ttcaccgtct gttttcttgt gaccatgtgg ttctggagca aacttgagga
     4081 aggtttcaag gaaggtctgc acaccaaagt ttgtcagggc tgaaccgaaa aagacaggcg
     4141 tcaattctcc agccagaata gcttcctctg aaaactcatt cccggcttca tttaaaagct
     4201 caatatcatc cttgacttgc tcgtagaaag gattgctacc aaaaagtttg tccccatctt
     4261 ctagactggc aaaacgctca tcccctttat aaagctctaa acgttggtta tagaggtcat
     4321 acaagccctc aaaggctttc cccatcccga taggccagtt catagggtag ctagcaatgc
     4381 ccaagatttc ttccaattct tgcaagagat ccaaaggctc acgaccgtca cggtccagct
     4441 tgttcataaa ggtaaagact ggaatgccac gatgtttcac aacctcaaac aatttcttgg
     4501 tttgagcctc gatccccttg gcagagtcca cgaccatgac cgcagcatcc accgccatca
     4561 aggtacgata ggtatcttct gagaagtcct cgtgccctgg cgtgtctaag atattcacgc
     4621 gcttgccgtc gtagtcaaat tgcataacag atgaagtaac agaaatccca cgttgcttct
     4681 cgatatccat ccaatcagat ttagcaaaag tccctgtttt cttccctttt accgtaccag
     4741 cctcacgaat ttcaccccca aagtagagta actgctcagt gatggttgtt ttccccgcgt
     4801 ccgggtggga gataatggca aaggtacgac gtttcttaat ttcttcttga atattcataa
     4861 gttctctttc tttgattctc tatttttctt gtttcaatag ctgagaatga tttttacatt
     4921 ggattttacc attcctttca acactccatt atatcggatt ttagcatttt tttcaatttc
     4981 tatttctttt cacttccccc tcccttattt ataggaaaat atggtaaaat agaacagact
     5041 aaaaatcatc atttcacgaa aggatgcaag atgaaaatta cgcaagaaga ggtaacacac
     5101 gttgccaatc tttcaaaatt aagattctct gaaaaagaaa ctgctgcctt tgcgaccacc
     5161 ttgtctaaga ttgttgacat ggttgaattg ctgggcgaag ttgacacaac tggtgtcgca
     5221 cctactacga ctatggctga ccgcaagact gtactccgcc ctgatgtggc cgaagaagga
     5281 acaaaccgtg atcgcttgtt taaaaacgta cctgaacaag acaactacta tatcaaggtg
     5341 ccagctatcc tagacgatgg aggagatgcc taatgacttt taacaataaa actattgaag
     5401 agttgcacaa tctccttgtc tctaaggaaa tttctgcaac agaattgacc caagcaacac
     5461 ttgaaaatat caagtctcgt gaggaagccc tcaactcatt tgtcaccatc gctgaggagc
     5521 aagctcttgt tcaagctaaa gccattgatg aagctggaat tgatgctgac aatgtccttt
     5581 caggaattcc acttgctgtt aaggataaca tctctacaga cggtattctc acaactgctg
     5641 cctcaaaaat gctctacaac tatgagccaa tctttgatgc gacagctgtt gccaatgcaa
     5701 aaaccaaggg catgattgtc gttggaaaga ccaacatgga cgaatttgct atggggggtt
     5761 caggtgaaac ttcacactac ggagcaacta aaaacgcttg ggaccacagc aaggttcctg
     5821 gtgggtcatc aagtggttct gccgcagctg tagcctcagg acaagttcgc ttgtcacttg
     5881 gttctgatac tggtggttcc atccgccaac ctgctacctt caacggaatc gttggtctca
     5941 aaccaaccta cggaacagtt tcacgtttcg gtctcattgc ctttggtagc tcattagacc
     6001 agattggacc ttttgctcct actgttaagg aaaatgccct cttgctcaac gctattgcca
     6061 gcgaagatgc taaagactct acttctgctc ctgtccgcat cgccgacttt acttcaaaaa
     6121 tcggccaaga catcaagggt atgaaaatcg ctttgcctaa ggaatacctc ggtgaaggaa
     6181 ttaacccaga ggttaaggaa accattctaa atgccgctaa acactttgaa aaattgggtg
     6241 ctattgtcga agaagtcagc cttcctcact ctaaatacgg agttgccgta tactacatca
     6301 tcgcttcatc agaagcttca tcaaacttgc aacgcttcga cggtatccgt tacggctatc
     6361 gcgcagaaga tgcaaccaac cttgatgaaa tctatgtaaa cagccgaagc caaggttttg
     6421 gtgaagaggt aaaacgtcgt atcatgctgg gtactttcag tctttcatca ggttactatg
     6481 atgcctacta taaaaaggct ggtcaagtcc gtaccctcat cattcaagat ttcgaaaaag
     6541 tcttcgcgga ttacgatttg attttgggtc caactgctcc aagtgttgcc tatgacttgg
     6601 attctctcaa ccatgaccca gttgccatgt acttagccga cctattgacc atacctgtaa
     6661 acttggcagg actgcctgga atttcgattc ctgctggatt ctctcaaggt ctacctgtcg
     6721 gactccaatt gattggtccc aagtactctg aggaaaccat ttaccaagct gctgctgctt
     6781 ttgaagcaac aacagactac cacaaacaac aacccgtgat ttttggaggt gacaactaat
     6841 gaactttgaa acagtcatcg gacttgaagt ccacgtagag ctcaacacca attcaaaaat
     6901 cttctcacct acttctgccc acttcggaaa tgatcaaaat gccaacacta acgtgattga
     6961 ctggtctttc ccaggagttc tgccagttct caataaaggg gttgtcgatg ccggaatcaa
     7021 ggctgctctt gccctcaaca tggacatcca caaaaagatg cactttgacc gcaagaacta
     7081 cttctatcct gataacccca aagcctacca aatttctcaa tttgatgaac caatcggata
     7141 taatggctgg attgaagtcg aactagaaga cggtacgacc aagaaaatcg gtatcgaacg
     7201 tgcccaccta gaggaagacg ctggtaaaaa cacccatggt acagatggct actcttatgt
     7261 tgacctcaac cgccaagggg ttcccttgat tgagattgta tctgaggcag atatgcgttc
     7321 tcctgaagaa gcctatgctt atctgacagc cctcaaggaa gttatccagt acgctggcat
     7381 ttctgacgtt aagatggagg aaggttcgat gcgtgtggat gccaacatct cccttcgtcc
     7441 ttatggtcaa gagaaattcg gtaccaagac tgaattgaag aacctcaact ccttctcaaa
     7501 cgttcgtaaa ggtcttgaat acgaagtcca acgccaggct gaaattcttc gctcaggtgg
     7561 tcaaatccgc caagaaacac gccgttacga tgaagcgaat aaagcaacca tcctcatgcg
     7621 tgtcaaggaa ggggctgctg actaccgcta cttcccagaa ccagacctac ccctctttga
     7681 aatttctgac gagtggattg aggaaatgcg gactgagttg ccagagtttc caaaagaacg
     7741 tcgtgcgcgt tatgtatctg accttggttt atcagactac gatgctagtc agttgactgc
     7801 taataaagtc acttctgact tctttgaaaa agctgttgcc ctaggtggtg atgccaaaca
     7861 agtctctaac tggctccaag gggaagtcgc tcagttcttg aatgctgaag gtaaaacact
     7921 ggaacaaatc gaattgacac cagaaaactt ggttgaaatg attgccatca tcgaagacgg
     7981 tactatttca tctaagattg ccaagaaagt ctttgtccat ctagctaaaa atggcggtgg
     8041 cgcgcgtgaa tacgtggaaa aagcaggtat ggttcaaatt tcagatccag ctatcttgat
     8101 cccaatcatc caccaagtct ttgccgataa cgaagctgct gttgccgact tcaagtcagg
     8161 caaacgtaac gccgacaaag cctttacagg attccttatg aaggaaacca aaggccaagc
     8221 caacccacaa gttgccctta aactacttgc acaggaattg gcgaagttga aagaaaacta
     8281 gacagaacaa aaccagccct aaggttggtt ttttcttctc taccaactcc caataactat
     8341 tttggcttta tttccagagt attttatggt aaaatgaaga gtaataatat ttattaaaga
     8401 ggtaaaaaca tgattgaagc aagtaaatta aaagctggta tgacctttga aacagctgac
     8461 ggcaaattga ttcgcgtttt ggaagctagt caccacaaac caggtaaagg aaacacgatc
     8521 atgcgtatga aattacgtga tgtccgtact ggttctacat ttgacacaag ctaccgtcca
     8581 gaggaaaaat ttgaacaagc tattatcgag actgttccag ctcaatactt gtacaaaatg
     8641 gatgacacag catacttcat gaatacagaa acttacgacc aatacgaaat ccctgtagtc
     8701 aatgttgaaa acgaattgct ttacatcctt gaaaactctg atgtgaaaat ccaattctac
     8761 ggaacggaag tgatcggtgt caccgttcct actactgttg agttgacagt tgctgaaact
     8821 caaccatcta tcaaaggtgc tactgttaca ggttctggta aaccagcaac gatggaaact
     8881 ggacttgtcg taaacgttcc agacttcatc gaagcaggac aaaaactcgt tatcaacact
     8941 gcagaaggaa cttacgtttc tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt
     9001 gaagaacaac ttggcgaaat cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc
     9061 gctactgcaa aggtagaggg ggttcactct ttttcaaaca gatcagtgtc tgataccctt
     9121 tcaaaacttt cactcggccg tggcatttat cttaaaaacg tggacgaaga actcacagca
     9181 gatatctatc tctaccttga gtacggagta aaagttccta aggtagcggt tgctatccag
     9241 aaagctgtca aagatgccgt ccgtaatatg gctgatgtag aactcgctgc tatcaatatt
     9301 cacgttgcag gtatcgtccc agataaaaca ccaaaaccag aattgaaaga tctatttgac
     9361 gaggacttcc tcaatgacta gtccactatt agaatctaga cgccaactcc gtaaatgcgc
     9421 ttttcaagct ctcatgagcc ttgagttcgg tacggatgtc gaaactgctt gtcgtttcgc
     9481 ccatactcat gatcgtgaag atacggatgt acaacttcca gcctttttga tagacctcgt
     9541 ttctggtgtt caagctaaaa aggaagaact agataagcaa atcactcagc atttaaaagc
     9601 aggttggacc attgaacgct taacgctcgt ggagagaaac ctccttcgct tgggagtctt
     9661 tgaaatcact tcatttgaca ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc
     9721 aaaggacttc tccgatcaaa aatctgcccg ttttatcaat ggactgctca gccagtttgt
     9781 aacagaagaa caataaaaag aaaaagtgtt tgatatctat caaacacttt ttctttgcct
     9841 cccactatct aaaaaaatga taatagatat aattgtaaac aaaaatccag ataggttttg
     9901 catgattgag aaagttaaaa aaactatggc agagaatcgt taatctcaga ttgtcggtag
     9961 aacgataaac aagggcaaaa aagaaaccaa tcagactata atataataaa ctaattggat
    10021 ctctgtgaga tagtatcaaa tgactaagcc caaagataag gcctgataag atgacatcta
    10081 aataatactt ggactaggga aagaaggtat tcataaaata ccctctatca agagtctcct
    10141 caaaaacagg accgatgatt acaggcagga caaaagataa gatagtcgat aaaaaggttg
    10201 gttgtccatt tgaaagaacc acggtaaaat actcatcatg aatattccta tgattaatca
    10261 aatgagcata gcgtgcccaa aaattaccga gaatctgaca aaccacataa gttgcaaata
    10321 aggagaagac aaatgaccag ttccagctct ttttcttttt taacctccaa attaatagaa
    10381 aaggaaactt cccactaatc ccactgttaa aataagagaa tagacatcag ctcctaaccc
    10441 taaaatgatc gtcacataca atccaattgt ttgtggtaaa taggtagata gtaaaataat
    10501 aagcaaaaat attccaaatt gtcttagttt ctttgtgttt ctcatcgtac ttttttgaaa
    10561 gattaccctg ttcggaagcc gtacttccaa gcatctatat aagaattaag tgccccttgc
    10621 ctcatatagg gagcaaattc tctataatat aaccatctac tatatccatc ttcccaaaca
    10681 gcaagaccac ctgaagtttg ctccaagtcc tcagttgaaa taactgtaaa tgtttctgta
    10741 cctgtcattg caagtacctt cttaaaatag attgttgtag gctcacattt atagtatatt
    10801 tctttttttg tctattttat agtctatctc ctcaactggc aatttttcga cctgaattgc
    10861 atttttccat aaaaaatgag acctttctag tctcatttag tcattcttag tattttctaa
    10921 atcgttgata gcgttcttcc agcaactctt ctagcggttt ttgtgaaagt ctagccagct
    10981 ccgtttggag ttcttttttg acactcttaa tcagttcttt actagaaagt cctatttcag
    11041 aaatcacctt atccaccacg tccatttcta acagttcatg cgaagtgatt ttcatcagtt
    11101 ctgctgcttc catggcgcga gtaccgtcct tccataaaat ggaagcaaag ccttctggac
    11161 tgagaatggc atagatagaa ttttccagca tccagacacg gtccgcgaca gctagagcca
    11221 gagccccgcc tgaaccacct tcaccgataa taatggcgat aataggaact ttcaggtcac
    11281 tcatttccat gagattgcga gcgatagctt ccccttgacc acgttcttcc gctccgacac
    11341 caggataagc acctgctgta ttgataaagg tcacaactgg acggccaaat ttctcagcct
    11401 gtttcatcaa ccgcagtgcc tttcggtagc cttctggatg tggttggcca aaattccgtt
    11461 tgaggttgtc ttgcaaactc ttgccttttt ggataccaac cactgttaca gcttgatctc
    11521 caagccaacc aataccacca acaactgcac catcatcacg aaaagaacgg tcaccatgta
    11581 attggataaa ttcatcaaaa atgcctgtcg caaaatccaa ggttgtcaag cgactctgct
    11641 cacgcgcttc tctgactatt tttgcaatat tcatctagga ctccctccat gcaatctgac
    11701 taggctagca atcgtatctg gtaagtctct tcttttgaca atagcatcca caaagccatg
    11761 ttctaatagg aattctgcct tttggaaatc ctcaggcaag ctttcacgaa ccgtattttc
    11821 aatcacacga cgcccagcaa aaccaaccaa gctctgtggt tcagccagaa tgatatcgcc
    11881 ttccatagcg aaagaagctg tcacaccacc agtcgttgga tctgtcaaaa tggtcaggta
    11941 aaagagacca gcatttgaat gacgtttaac cgccgcagag atcttagcca tctgcatgag
    12001 actcatgatt ccttcctgca tacgggctcc accagaggct gtgaatagga caactggcaa
    12061 tttttcgaca gtcgcatact caaacaaacg agtgattttt tcacctacaa ccgtacccat
    12121 agaagccatg ataaagttag aatccataat cccaagagcc acagtctgac ctttaataag
    12181 agcagttcct gtcacaacgg cttcatgcag acctgttttt tcacgcatag atgccagttt
    12241 cttttggtaa ccagggaaat gcaagggatc cttgctttca atccctgtaa acaattcttt
    12301 gaaggttccc atatcaatcg tcaaagccaa gcgttcttgg gcagaaatac gaaaggtata
    12361 gctacagtgc ggacagatac gttcacttcc cagatccttc tgatagatgg tatgcttaca
    12421 gcctggacac tgggaaaata attcatctgg aacctctggc ttagcttgag gtttttccct
    12481 aactgaacga ttgggattga ttcgaatata cttatctttt ttactaaata gagccattga
    12541 ttcccctttt cggtttaaac tcttaaagtc attttattct ttttcttgat atttaggtaa
    12601 gaaggtttcc atcaagaagg aagtatcata atccccagca atgacattgc gatctgaaat
    12661 gaggtcaagc tggaaatctg cattggtctg cactccttca atctctaatt catagagggc
    12721 acgttgcatt ttcatcaagg cgtcaaaacg attttcgccg tgtactatga ttttggcaat
    12781 catactatca taataaggcg gaatggtata acctggataa actgctgaat ccacgcgcaa
    12841 gccaactcca ccacttggca gatagagatt agtaatctta cctggacttg gagcaaagtt
    12901 aaaggctggg ttttctgcat tgatacgaca ctcgatggca tgaccgcgta ggacaatatc
    12961 ttcttgctta acagacaaag gctgacctgc cgcaatgcaa atctgttcct taacgatatc
    13021 aacacctgaa acaaactctg ttactggatg ttctacctga acacgagtat tcatctccat
    13081 gaaatagaaa ttgctacttg cttcatcaag aagaaattca atggttcctg cattctcata
    13141 gccaacaaac tctgccgctc gaacagcagc agcacctatt tcatgacgca gcgtttttcc
    13201 gattgcaatc gagggacttt cttccaaaac cttttggtta ttcctttgaa gagaacaatc
    13261 ccgttcaccc aagtgaatca catgtccatg ctcatcacct aggatttgaa cctcaatgtg
    13321 ccgagctgga tagataaccc gttctatgta catggcacca ttgccataat tggccttggc
    13381 ctcactagag gcagtttcaa aggcagaaac gaggtcatct ggtttttcaa ccttacgaat
    13441 ccctttacca cctccacctg ctgaagcctt gagcataaca ggatagccaa ttttttcagc
    13501 aacaatcaaa gcttcttcag agttatgcac ttctccatct gaacctggta taacaggcac
    13561 acctgcttta atcatctgag cacgcgcatt gatcttatcc cccatcatat ccataacatg
    13621 accagatgga ccgataaact tgatacctac ttcttcacac atggtcgcaa atttggaatt
    13681 ttcactgaga aatccaaaac cagggtgaat agcttctgcc tcagtcaaga ctgcagctga
    13741 tagaactgca ttaatattga gataagactc tgttgccttg ccaggaccaa tacaaactgc
    13801 ttcatctgcc aaaagcgtat gaagagcttc cttatcagca gttgaataaa ccgctaccgt
    13861 cgcaatcccc aattcacgtg ccgcacggat aatacgaacc gcaatttcac cacgattggc
    13921 aattaaaatt tttcgaaaca tggagaacct ccttagttcc caattgcaaa agtaagggta
    13981 ccactggctg caagcttgcc atccacttca gcctttgctt caaccacagc tatggtgcca
    14041 cgacgtttta caaaagtcgc tgtcataacc aattggtcgc ctggtacaac ttgcttcttg
    14101 aacttaacct tgtccatacc agcgtaaaag accagttttc ctttattttc aggttttgat
    14161 aactccaaca caccggcagt ttgcgccaag gcttccataa tcagaacacc tggcataact
    14221 gggtattgag gaaagtggcc gttaaagaaa ggctcgttga tggtcacatt tttgatagca
    14281 acaatggtat cctcgctcac ttccaagaca cggtccacta gaagcatagg ataacggtgg
    14341 ggaagagctt ctttgattcc ttgaatatcg atcatttgat acgtaccaat cctttaccaa
    14401 actcaaccat ttcttcgtta gagacgagaa tttccgttac cacaccatcc ttaggagctg
    14461 ggatttcatt catgactttc atggcttcga taattaccaa tgtttgacct tttttgacac
    14521 tatcaccaac tgtaacgaag gcaggtttat ctggtccagc agccaagtaa accactccaa
    14581 caagtggact ctctacaaga tttccctcag tagccacact tgcttcagct ggagctggaa
    14641 cttcttctgc tacagtctct gctggagcag atgtaggagc tactggactc ggtgttgcta
    14701 gaacgggtgc tggagcgact tgagttgcaa cttcaggcac aggtctcgct tcattcttgc
    14761 taaactgcaa ctcatccgtc ccatttttat aagaaaattc tctcaaactt gactggtcaa
    14821 attgagtcat caagtcttta atatcgttta aattcatact tatctattct cccaacgttt
    14881 gaaagcaaga actgcattgt ggcctccaaa accaaaagta tttgaaatag cgtatggaat
    14941 ttctttctcc aagccttgtc cataaacgac attagcttcg atataatctg atacttcact
    15001 tgtcccagct gtcattggta caaagttatg acgcatagct tcgatggtga cgatagcttc
    15061 tactgcaccc gcagccccca gcaaatgtcc tgtaaaagac ttggttgatg atacaggtac
    15121 ttccttacca agaacagcta cgatagcacc actttctcct ttttcattgg caggagttga
    15181 cgttccgtga gcattgacat aggctacttg ctctggagaa atctcagctt cttccaaggc
    15241 tagtttgatg gccttgatag ctccctgacc ttctggatgt ggagaagtca tgtggtaggc
    15301 atcacaagta tttccgtaac caaccacttc agccaggata gtagctccac gtttttcagc
    15361 gtgttcaaga ctttctagaa ccaacatccc tgaaccttca cccataacaa acccattgcg
    15421 atccttatca aatgggatcg aagcacgagt tggatcctct gtagtagaga gagctgttaa
    15481 ggcttggaaa ccagcgatgg caaaaggtgt gatagaagct tctgttcctc ccaccaacat
    15541 cacatcttgg aaaccaaact taatagagcg gaaggcatcc ccaatcgcat catttgatga
    15601 agagcaggca gtattgatag atttacaaac accgtttgca ccaaaacgca tggctacatt
    15661 cccagaagcc atatttggta aagcttttgg aagagtcatt ggtttgacac gtttgggtcc
    15721 tttttcatga aggcgaagta cctgatcttc aatttccttg attccaccaa taccagatgc
    15781 aacgataaca ccaaaacgat ccctattaag agcctctaca tcaagattgg catgatttac
    15841 agcctcttgg gctgcataca aggcatataa agaatagtta tcaaaacggt tggtatcttt
    15901 ttttacaaag tatttatcga acggaaaatc ttggatttct gccgcattat gcacatcaaa
    15961 gtcactatga tcaaattttg taatgccacc aatgccgatt ttcccagttg ctaaactatt
    16021 ccaaaattct tctggtgtat ttccgattgg agatgttact ccataacctg ttaccactac
    16081 tcgatttagt ttcattcttt tcacctctag ctttcgctac atacttaagc caccatcaat
    16141 ggcaaccact tgaccagtta gataatcttg gcctgctaaa aatactgtca aatctgcaac
    16201 ctgctctgcc tgcccaaatt ctttcatcgg aatctgagct agtgtagctt ccttaatctt
    16261 atctgataag atagctgtca tatcagactc aatcattcct ggagcaatca cattgactcg
    16321 tatattccga ctagcgacct cgcgtgccac agacttggta aagccaatca agccagcctt
    16381 agaagcagca tagttagctt gaccaatatt ccccatcaaa ccaacaacac tagacatatt
    16441 aatgatagca ccttctctgg ctttcatcat cggtttcaag actgattgtg tcatattaaa
    16501 ggcaccagtc agattgacct tgagcacttt ttcaaaatct gcttctgtca tcttaagcat
    16561 aagagtatct tgggtgatcc ctgcattgtt gaccaaaaca tctactgaac ccagttctgc
    16621 aatagcttga tcaatcatac gcttagcgtc tgcaaaatct gatacatctc ctgaaatggg
    16681 aaccaccttg ataccatagt ttgaaaactc agcgagcaat tcttctgaga ttgccccacg
    16741 actgtttaag acaatgttgg ctcctacttg agcaaacttg tgggcgatgg caagaccaat
    16801 tccacgactc gaacctgtaa taaagatatt tttatgttct agtttcattt ttttcctttc
    16861 aaaacttcta cttattttag tctatttctc taaaagtgct actaaactcg cttgatcttc
    16921 cacatgagct aagtgagcag tttgatcaat ttttttaaca aaacctgaca agactttccc
    16981 cggtccaatc tcgataaagt tgcttatgcc tgcttcttgc atgaccccaa tactttcata
    17041 gaaacgaacg ggttccttga cctgacgcgt caagagctga gcaatgtcct ctttttgcat
    17101 cacagcagct tctgtattgc cgactagggg acaagtaaaa tctgaaaaac ttacctgagc
    17161 tagagtttca gctagtttct ggctagctgg ctcaaggaga gcggtgtgaa agggacctga
    17221 caccttaaga ggaatcaagc gtttggcacc tgcttcttgc aaaagttcaa ccgctcgatc
    17281 aactgcaacc acttctccag caatgacgat ttgtgcaggt gtgttatagt tggctggagt
    17341 aaccactcca agttcagaag ctttttgaca ggcttcttca atgacctcta ctggcgtatt
    17401 gagaactgct accatcttgc cagagtcagc aggagccgct tcttccatat aggctccacg
    17461 cttagctacc aaggcaaccg catcttcaaa atccaaggcg ccgcttgcca ccaaggcaga
    17521 gtattctcca agagacaaac cagcaaccat atcaggctga tagccctttt cttgcaataa
    17581 acggtagata gcaaccgaag tcgctagaat ggctggttgc gtatagcggg tctgattgag
    17641 tttgtcctct tccgtatcga tgagataacg taaatcataa ccgagcacct gactcgctcg
    17701 atcaatcgtt tctttgacaa tcggatactg atcatagaaa tcccgtccca tccctagata
    17761 ctgggcacct tgaccagcaa ataaaaaggc tgttttagtc atttcttaca actcctgccc
    17821 agcgagaggc ttcttcttga attttcttag cggctccgta atacaaatct tttaggattt
    17881 cttcagctgt ttcttcttta gaaacaagtc ctgcgatttg acctgccatg acagagccac
    17941 cctccacatc accgtgaaca actgctttgg ctagggcacc tgctcccatt tgttcaaaga
    18001 tttctaaatc aggatcttcc tgcttaaagg catctttttc agccagttca aaatctctag
    18061 tcaactgatt tttaatagca cgaacagcat gaccaaagtg ctgagctgaa atcgtagtgt
    18121 caatatccct tgcttttaaa attttctcct tgtagtttgg atgagcattc gactcttttg
    18181 caactacaaa ccgtgtcccc acctgtacag cctctgcacc tagcataaag ccagccgcag
    18241 caccttcacc atccgcaatt cctcctgcag caataacagg aatagataca gctgtggcta
    18301 cctgtcgcac caaggtcatg gttgttaatt taccgatatg ccccccagct tccattcctt
    18361 ctgcaataac agcgtctgca ccgatttttt ccatgcgttt agctaaagcg acactaggaa
    18421 caacaggaat aacgattatc ccagcttcat ggaaacgttc catatacttg cttggatttc
    18481 ctgctcctgt tgtgacaact ttaacacctt cttcaataac gagatccacg atatcttcca
    18541 caaagggaga taagagcatg atgttgaccc caaagggttt atcagtcaat gatttgattt
    18601 tatcaatatt ggccttgaca acttctttcg gggcatttcc cccaccgata attcctaatc
    18661 ctccagcctt ggaaacagcc cctgccaaat caccatcagc aacccaggcc atccctcctt
    18721 ggaaaatagg atagtcaatc ttcaataatt ctgtaatacg cgttttcata gtgcctccaa
    18781 ccttccttgc ttacgtaata gttcgatttc accataattt gacagtcaaa ctattaccta
    18841 aacaagaggg agtgggtttc tccctactcc ttctactaat attctgctta tttttcttgc
    18901 tcttcaacgt aagcaaccaa gtcaccaact gttttcaagt cattttctgc ttcgatttgg
    18961 atatcaaaag catcttcgat ttctgagatt acttggaaca agtccaatga atctgcgtcc
    19021 aaatcatcaa aagttgattc aagtgttact tctgatgcgt cttttccaag ttcttcaacg
    19081 ataatttctt gtactttttc aaatactgcc atgataggac tcctttaaaa taaatagttt
    19141 ttttataaca atgtgttcac cacatgatta cctaaattgt aagaatgagc gtgccccagg
    19201 tcaagcctcc accgaagcct gatagaagaa cagtctggct accatctaaa gggatgagac
    19261 cttgttctac acactctgaa agtaaaatcg ggatactggc tgcactggta ttgccatatt
    19321 ccatcatatt ggctggaagt ttggctcggt caacaccaat ttttctagcc atcttatcca
    19381 aaatacggtc attggcttga tgaagtagca gataatccaa gtctgtcacc tctataggag
    19441 attcatcaat agtctgcttg atagacttgg ctacatctcg aatggcaaaa tcaaagactg
    19501 tgcgtccatc catcttcaaa aacgaatctg cactttcttg atctgaaaat ggagaatgca
    19561 aacctgaatg cccataagtt aaacactcgc tgcgacttcc atcgctattg agactctcag
    19621 ctaagaaatg ctcttgctcg ctagcttcta acaagacacc accagcacca tctccaaaca
    19681 acacagctgt tgatcgatcc gaccaatcga ctgccttaga gagggtttca ctaccaatca
    19741 ccaagccttt ttgaaagcga ccagaagcga taaacttttc agcagttgaa agagcaaata
    19801 caaatccact gcaagccgcg gttaagtcaa aagcaaaggc tttattagcg ccaatattag
    19861 cttgaacacg agcagctgta gagggcatca tcgaatctgg agtaatggta gctaggatga
    19921 taaaatccag ttcttttcct gttattccag cttttgccat cagtttctta gcaacctctg
    19981 tagccaaatc actggtagat tctgttcttg aaatatgcct ttgtcgtatt cccgttcgac
    20041 ttgaaatcca ctcatcattg gtatccataa tctgagccaa gtcgtgattt gtaaccactt
    20101 gctctggcac ataatgagca acctgactta tttttgcaaa agccattatt tcaaatcctc
    20161 caaaaattgg taaagattag tcaagccttt acccatgaca gcaatttctt cctcgctcat
    20221 gccatcaata attttttcta ccatggcctt gtggaagcgt ttatgcagtc tatgaatcaa
    20281 gcgacccttc tttgtcaaat gcagatgcac cacacgacga tcctgttctg accgaactcg
    20341 ctcaatgtag cccttacgct ctaaattgtt caaacttgtc gtaacagttc caagagttac
    20401 catcaactct tttgacactt gacttggagt cacatctgga gccttaccga tgacatcaat
    20461 cgtatgcatt tctttgatgg agatatcctt aaaacgacta cctctcaagt tcacttcctc
    20521 aattacaagg acattgttaa atatagatgt taaatattca ttgattcgtt ggtagtccat
    20581 ttttcatatc cctccttctt caaaaaactt ttacaatcaa aacatttgac agaaagaatt
    20641 atatcaaaat tcaaagaatg atgcaagtat tttttatttt cctgtaaatt taggtcttct
    20701 tctctccgaa tgagctcgca ctccttcttt gaaatcctct gtttgagcta aggatttctg
    20761 taggttcagt tctaaagtag cgtaaccctg ccagtcttta aattggctct cccaaaccaa
    20821 cttcttaatg gcagcatagg aattacttga agcacgtctt aattttttaa gaagctgttc
    20881 tctcgtcttt tcaagttttt cagcttcaga aacgcggtaa accaaccccc attctagggc
    20941 tttttctgcc gttaaagcct ctcctgtcat agctaattga gcagcacgcg tcacaccgat
    21001 actgcggctc aagagatgaa ttccccctgc atctggagcc aaaccaacac caacaaaggc
    21061 ttggataaac ttagccttat ccgtcgccaa acagaaatct gccgcaacag ccatattcgc
    21121 tgcggcacct gcaacagcac cgtcaacttc cattaaaaca ggtttggcta tttgcttgat
    21181 tttataagaa atcgtattga ccaactctgc gatttttgtc aatgatggaa tatcatcctc
    21241 atccactgcc cgcttcatct ctaccaaatc tcccccaact gagaagacct ttccattggc
    21301 attgattaag ataaaatgca cagctggatt ttcttctgcc aaagtcagag cttctaaaat
    21361 ctcctcacac atgggaatat gaaaaccatt tgcgacctca ggacggttca aggtaaggat
    21421 tgccaagtcc tcttcaagct gataaataat gtgttccatc agggctcctt tttattttat
    21481 aagcagttta tactcttcga aaatctcttc aaaccgcgtc agcttccatc tgcaacctca
    21541 aaacagtatt ttgagctgac ttcgtcagtc ttatttacaa cctcaaagca gtgctttgag
    21601 cagtctgcgg ctagcttcct agtttgctct ttgattttca ttgagtgtta aattatttca
    21661 ctgtcaaagt atatcttttt taggagcaga aagcaagaaa aaatcgactg aaagtgtctc
    21721 agccgataag aaaggctcgc tttaggctag aacgcatctt attttcttca ttgaaaaaag
    21781 cctttctttc tgctataatc gtataaaata cttactttag gagttcttat gaaagttgtt
    21841 aaatttggag gtagttctct tgcctctgct agtcaattag aaaaagtttt aaacatcgtc
    21901 aaaagcgatt cagagcgtcg ttttgtagtc gtttctgcgc ctggtaaacg caatgctgaa
    21961 gatactaagg ttacggatgc cctgattaaa tactaccgcg actatgttgc gggtaacgat
    22021 attagcaaga gccaaagctg gattatcgac cgctatgctg ctatggttag tgaattggga
    22081 ctaaaaccag ctgtgctaga aaaaatttct aaaagcattc acgccttggc cactcttcct
    22141 attgaagaaa atgaatttct ctacgatact ttcctagcag ccggtgaaaa taacaatgcc
    22201 aaattgattg ctgcctactt taaccaaaat ggtatcgatg cacgctatat gcaccctaga
    22261 gaagctggga ttgtggtcac aagtgaacct ggtcacgctc gcatcattcc atcaagttat
    22321 gacaagattg aagaattgac aaacaccaat gaagtccttg tcattcctgg tttctttggt
    22381 gtcactaagg aaaatcaaat ctgtactttc tcacgtggag gttctgatat tacaggttct
    22441 atcattgctg ctggtgtcaa agccgacctc tatgaaaact ttacggacgt tgatggtatc
    22501 tttgcagccc accctggtat tatccaccaa ccacactcga ttcctgagtt gacctaccgt
    22561 gaaatgcgcg agttggccta tgcaggcttc tcagtccttc atgacgaggc tcttcttcct
    22621 gcctaccgtg gaaaaattcc tctggttatc aagaatacca acaaccctga ccatccaggt
    22681 actcgtatcg ttctaaaaca cagtaatgat gaatttccag ttgtgggaat tgctggtgac
    22741 tcaggctttg tcagtattaa catgtcgaaa tacctcatga accgtgaggt tggatttggc
    22801 cgcaaggttc tgcaaatcct ggaagaactt aacatcggtt gggaacatat gccaacaggt
    22861 atcgacgatc tttctatcat tctccgttct cgccaactaa ctcccatcaa ggaagaagaa
    22921 atcctgcgtc agttggttca aaaggctaaa gtagatcatg cagaaatcga acacgacctt
    22981 tctatcatta tgattgttgg tgaaaaaatg aagagccaca tcggagtgac tgctactgcg
    23041 acacgcgctc tatctgaaaa caaaatcaac atccagatga tgtctcaagg ttctagtgaa
    23101 gtttctatta tgtttgttgt caataaagac caagagaaag cagcaattaa agccctctac
    23161 aatgcctttt ttggagaaag taaggaagac taagcatggc tcaatcactt aacaaaacag
    23221 tactcctcag tacgacaggc acttcctacc tctctatcgc tgggaaagtt gggaaattcc
    23281 ttgtcggaga tcaggctttg gaattttacc cagatgtcaa tgtcgaacaa tttatccaga
    23341 ttccttggag ccatatcaat cagattggag ccaatgtcac tggatgcaaa atcagccgcc
    23401 acttcgaagt ctttacagac aaaggaaaat tcctctttgc ttcaaaagac tcaggtgcca
    23461 ttctcaaaat tgcacgcgaa aaactaggca atgacaaggt cgtcaaactt ccgaccctga
    23521 ttcagacaat tagccaaaaa tttaaaaatc tatttgcaaa aaagtagaaa ctttagtata
    23581 atcatagcaa cggataagta ggttatcttc ttctttcaga aagtctgcgg gtactgcgag
    23641 cagataggag ggataggtga aattctaccg ttagtaacaa ttacatacac aatcaagtgc
    23701 acacctgtga agttggatgg aaccgtggcc ctgccactcc aacgttttgt caggcgtgct
    23761 tttttcataa aggagttctt atgttagata tcaaacgtat tcgtacagat tttgaagctg
    23821 tcgcagaaaa attagctaca cgtggtgtag atgctgctgt cttgaatgaa atgaaagaaa
    23881 tcgatgctaa acgtcgtaac atcttggtca aggttgaaac tctcaaagca gaacgtaaca
    23941 cagtttctgc tgagattgcc caagctaagc gcaacaagga aaatacagat gacaagattg
    24001 ctgccatgca aaatctatct gctgaggtta aagccttgga tgctgaattg gcagaaatcg
    24061 atgctaaatt gacagaattt acaacgactc ttccaaatat cccagctgac agcgttcctg
    24121 ttggggctga cgaagacgac aatgtggaag ttcgccgttg gggtactcca cgcgagtttg
    24181 acttcgaacc taaagctcac tgggatctcg gtgaagacct tggtatcctt gactgggaac
    24241 gcggtggtaa ggtaacaggc gctcgcttcc tcttttataa aggcctcggt gctcgtttgg
    24301 aacgtgctat ctacaacttt atgttggatg aacatggaaa agaaggctat actgaagtca
    24361 tcacacctta catagtcaac catgattcta tgtttggtac tggtcagtat ccaaaattta
    24421 aggaagatac ttttgaactc agcgatacca actttgtctt gattccaact gctgaagttc
    24481 ctctgacaaa ctactaccgt gatgaaatct tagacggcaa agatcttcca atctacttca
    24541 ctgccatgag tccgtcattc cgttctgagg ctggttctgc cggtcgtgat acgcgtggct
    24601 tgatccgttt gcaccaattc cacaaggttg aaatggtcaa atttgccaaa ccagaagaat
    24661 cttacgaaga attggaaaaa atgacagcca acgctgaaaa cattcttcaa aaactcaacc
    24721 ttccataccg tgtcgttgct ctctctactg gagatatggg cttctcagct gcgaagactt
    24781 acgacttgga agtgtggatt ccagcacaaa acaattaccg tgaaatctca agctgttcaa
    24841 acacagaaga tttccaagcc cgtcgtgccc aaatccgtta ccgtgatgaa gcagatggca
    24901 aggtgaaact ccttcatacc ttgaacggtt ctggacttgc agttggacgt acagtggctg
    24961 caattcttga aaattaccaa aatgaagatg gttctgtgac catcccagaa gcacttcgtc
    25021 catacatggg tggagctgaa gtcatcaaac cataaaaaat aaggtttagc tatttctagc
    25081 tagacctttt ttcgtaacca aatcagataa gcacctagta caaagaataa aatagttagg
    25141 catataatgg tttcagccaa taccaggtaa tccagaaatg gaagtttcaa aattccctga
    25201 gccatcttga gcgaggtcgc tgtgataatg gttgggaagg tgagggctga gaaggctggt
    25261 tgaaaacctt gttttaaaat gttgggcaga cgagttaaaa caaagaaaaa gaaggattga
    25321 gaagccaaaa tcatgacaat caagacccaa gtcggcaggc tggttcctcc tactcgaact
    25381 agagaagcca agagtagaga gaaaggagca cagtagattc cttcttgtcc aagcaaggct
    25441 agtgggagtg gatgtttctt taaatcgcta taaataaggg gatagagata gaaggtcaag
    25501 agaaaaccaa aactcaaggt cgcataggca atttcgataa tacctaccag aggataggtc
    25561 aaggcagcca ctgctatccc cacatagaga accgtccaac ttggagtggc atgaaccctc
    25621 cgccctgaac aagcaaactt gatggtaaaa ccagcaatca aggtcaaatc caagagaaat
    25681 gaaaaccacc aaatcccttg tgctaccaaa ggaagataag agaatacgcg aaagacatag
    25741 gtcgataaaa tcatcccagc cataggaaag gttgccattc ctgacaaaag agggggcttg
    25801 gtcaattctt gcttggtttc tttccaatta aagagatgca gaattagaaa gtaaatccat
    25861 aaaaccaaac cagtcagact aaaaagatgg gatagaaccg gcaacgtatc taaaataaga
    25921 tttccagctc ctgccaaacc taacaaacaa cctgaaaata ctaaggggag ttttttcatc
    25981 ctaacctcca ataatcatgt tagtttcagt ataacataaa agcgcttaaa tgaggattta
    26041 aaaaaacgaa gtccgcttat ttcagacttc attttactca gatatgaatt aggcataagg
    26101 ttgcaattct ggattaattg gtgtattagc taagttgttg gcatagttac agaggattgc
    26161 taggctgaca ccaaaaacca catccaaggc attttgttga gtgtagccag cttctaaaaa
    26221 ctcagacaag gcttcatctc ctacacgacc cttggtattg ataactgcca aggtaaactt
    26281 agctagggta tccaatttag gatctgtttc aattggagta cgattgcgaa gagcttgaat
    26341 caagtcatca ttcatctgga tttgtttgat ggaaaaggct gtgtgacctg cgacacagaa
    26401 ggcacaacca ttggtcacgg ctgccgtgat ttgcaccact tcacgctcaa cgggtgtcag
    26461 gctgttgcga cggtggatag atgagacaat ttggtaggct tctaaaacag tcggggcatt
    26521 ggccaagaga ccgattaggt tgggaatata gccattgttg tctttttcta ctgtttcaag
    26581 aatttctttc acttctgctg gtgctgactc tactgtatgg atagtaaatg ttgtcataag
    26641 atacctcttt tcttattatt gacactaata ttattggaaa atcttataaa atcctgattc
    26701 ctaagtttat ctaagataaa gctttattct ctcataagat tttcgttgtt atattagttt
    26761 atcacacttc cagtcacttg tataatatat attatatatc aggctgataa aaattattta
    26821 taggcaaaaa aatcacacga gctgtgtgat tccattattt gtcaaaatac tttttagttt
    26881 cagcaataac gactggcgac aagaccaaga gggcaatcaa gtttggcaga gccatcaagg
    26941 cgttaacgat atctgcgata atccagacca tatccaactc gataaatcct cctaacaaga
    27001 ccatgagcac aaaaaccaca cggtagagcc agataaagcg aaccccaaag aggaactcaa
    27061 aacagcgttc tccgtaatag ttccaaccta gaatcgttgt aaaggcaaaa agtacaagga
    27121 agatggtcaa gagggcaggc ccaaagtatg aaaagactgt tgagaaagct gactgagtca
    27181 aggcaacccc attcaagtca ccactccaaa ctccagttac caagatggtc aaaccagtta
    27241 gagtacaaat gatgagggta tcaataaagg ttcctgtcat ggaaatcaaa ccttgctcta
    27301 ctggttcatt tgtcttggca gctgcagctg caataggagc agaacccaga ccagattcgt
    27361 ttgagaacac accacgcgcc acaccatttt gaatagccat ccgaacgcta gcaccagcaa
    27421 atccacctac cgcagcaagg ggactaaaag ctgaggtaaa gactaaagcg attgtgccag
    27481 ggatttttcc gatattaaag aaaataactg taagagttcc taagatataa atgatggcca
    27541 taaaaggaac aacagtagtt gaaaccttag aaatagactt gagtccacca aagactgcaa
    27601 tcgctacaaa gacagacaag acgagagctg tgatggctgg cgaaatcgtc gttgtatttt
    27661 ggatagattc tgtaatcgag ttgacttggg tgaaggttcc gattcccaag agagcaacca
    27721 atactcctgc tactgcaaac aaaacagcaa gtggtcgcca cttttctccc atccctagaa
    27781 ggatatagtg catgggacct cccgctactg caccatggtc gtccttggtg cggtatttga
    27841 tggccaagag tccttccgca tacttggtag ccattccaaa gaaagccgcc atccacatcc
    27901 aaaatagagc tcctggtcca ccaaccttga tagccgtcgc aactcctatg atatttcctg
    27961 ttccaacagt tgatgccaag gctgtacaca gagctgcaaa actggataca tcaccatgtc
    28021 ccttatcctg gataaaaata agctgaaagg ccttgggcag acgcaaaacc tgcaagagtc
    28081 ctagccgaat agttaggtaa atccctgttc cgaccaataa aatcaagagg ggcggtcccc
    28141 aagcaaaagc atcgattgat ttaagcaatt ctaacatttc cttctcctat cgtttcaacc
    28201 ccaaaagaaa gagcacatgc aagatacatg tactctggaa tgcttagata aatgctaaaa
    28261 agcggtctat cctagctctg tccttttacc tgagagtttg agcagttgcc tgccttgccc
    28321 cttcggtgcc tttacggtct ctccagagtt ccgtccattt acagtcatgg aaaatcaaac
    28381 gattccccac ttctattaaa cttcattcgg tgttggtatt taattgattc taattttaca
    28441 aaaaatgttg gcttttgtca atgtgtttat tagtaaaaat tagttcaaca gtttttactt
    28501 tataaagtcc agaatactgc tatcctttaa aagtgacaat agtcgcacca ctgcctccag
    28561 cattttgtgg ggcatagccg aaactcttga catgtttgtt tctttgcaag tatttggtaa
    28621 ctccttcacg gatgactcct gttccgatac catggatgat atcaacttga gccatattgt
    28681 taagcaaggc ttggtcgatg aaggtatcta gctcattcat ggcttcttca tagcgcttgc
    28741 ctcgaagatc cagtctagct tgaggtcctc gcccagaagt tcgtttcaca acattgacct
    28801 gtttcttctt gactggtttt tcttgctggg cttgaacaag atcaaactct ttctcttcca
    28861 aggtcatctt aatcaagcca acttgggctt cccagcggcc gtccttgagt tgactggtca
    28921 aggtaccacg ctgaccataa ctgagaacca cgatatcatc tcccaccttt ggagctcgtt
    28981 ttttcttggc cttttgaagg accttgtttt tagacaagtc cactttttca ggagccaatt
    29041 ttttcaactt ggccttggct tcaatgattt cgtggggctt gagttgggat ttactgtgga
    29101 gatttttgag aatctggtca ctttcactta gggccatatc cacaatctca gcagcctgtt
    29161 cacgcgcctt gttaagctcg gtttcctttt cacgattaag ctcgttgtag agttttttta
    29221 gcgcacggtt catcttgaga ttttcttgct ccacctcacg gatattgtcc aaacgtttgc
    29281 ggctttccag cgtctgctct tctaattgct caatgatacg attgacgtca ttgtcctgat
    29341 cgatctgctg actggcatct cctacgataa cttcagatag gcctagacgt ttggcaattt
    29401 caaaggcatt acttcggcca ggaacaccct gcataaagcg ataggtcggg cgaagagttg
    29461 cagtatcaaa ctccatactg gcattttgca caaaggctgt ctcaataccg taggccttga
    29521 gttctggata gtgggtcgtc gccatggtct tgatttgacg caggcgaagg tcctccagaa
    29581 tagccatggc aagggctgct ccctcttggg gatcagtacc agcccccagc tcatccaaaa
    29641 gtaagagtga atgttggttg accttgccaa gaatatccac gatattggtc atatggctag
    29701 agaaagtaga caagctctgc tcaatagact gctcatctcc aatatcagca aagatttctt
    29761 caaaaatacc aacacgactt cccttgtctg ctaaaatcgg caatcctgac tgggccatga
    29821 cctgtgtcaa gcccagagtt ttaagcatga tggtcttccc acctgtattg ggacctgtaa
    29881 tgacaatagc tgttaaatct tgaccaaaat ggacatcatt tgcgacgaca tttttgacca
    29941 aaggatggca gacatggagc agttgaatct cttgattttc tgacagctga ggcacgactg
    30001 cttgtctttc ttggataaat cgaaccttgg cacgaatcaa gtccagatga ccgataatcc
    30061 aagcgtcatt agcaatctca gccgcatgag ggcggacacg ctcagaaatt tcttggagaa
    30121 tgcgaagcat ttcatagcgc tcatctgctc gcagactagc aatttcttcg ctcagtttga
    30181 ctacctcacg tggttcgata tagacggtgt ttccactagc agaaatatca tgaacgacac
    30241 ctgcaatctt attgcggtag gtgtttttga ctggtaaaac ctgacggcca tttctgctag
    30301 caacaattcc ttccgtcaac atctgcgctt tttgcttgag caagtcttgt aaaacatcgc
    30361 gtacctgact ctcgctatca tgtatttttc gacggattcg cgccaattct tcactggcaa
    30421 aattttcaat gaaacccgca tcattaaagg cctgaagatt tccttgtaat tgcggaaaat
    30481 catgtaattt ctcaaaccaa agggctaatt cttccaagct gacattttcc agattggcgt
    30541 aaaaactttg aagttctcgg ctggcaagaa gcacgcgttt caagagtagg aactcctcga
    30601 tattgagatc cgctcccatc tccaacctct tgcagactcc tgcaatttcc ttagttgaga
    30661 gaatagtaaa atgcggttgc tcgacgaaaa gaacctgcat ttctttcatc tcagcaaaag
    30721 cctgtttgat tttatctgct ttggcagtcg gagccagctg tctcaattgc tccaagccct
    30781 gctcggtcaa caaatgaggc tcaaacaagg ccttgacctt atcgaactct aatgtttcta
    30841 atattttctt attcatcttt atttccttgt ctttgaatgt ctaggtgtgg tagcttttta
    30901 cattctgata gattcgagtc aaatctgtaa acaaagggct aggaaaactc ctgccctttt
    30961 tatccgatta aatttgtcac ccagatttgt ttgagccaac tggttgttat cggtatgctc
    31021 tggatgatgt gttttgcgac gatactcttt tcaagaggat tttgtataac tgccatgggg
    31081 atggtcgcca agattgtcaa ggccatttgc aagacaaata aggtcaccaa catggacaag
    31141 atacctgctg aaacttggaa caacttacca cccagttttt tgctaggaat caagtgtaag
    31201 agaagaccaa gcaaacgacc aatactatag acaatcccaa atacaagcaa gtagccgata
    31261 cctgcataaa agaccttatc cagctgaaag agttgatccg atgggaaaaa gaaagtcccc
    31321 tgaccttcct gcgaatttgc ataagggagc aataaatgga attgctctcc aagcccctta
    31381 taaaactggc cagccataaa agccgatgcc atggctgaaa tcaggtaata aacctgtaag
    31441 agcaagcctc tccgatagcc gatataaaat ccccaaacca agaccaatag aagaaggaat
    31501 gaaatcataa ggaatcctca atcttgctct gttcttgctt acaagtcaca agcttgtgac
    31561 ggagttcttc tagctcttgc tccttatcgt caaattcaat ctcacggctg agctgagttg
    31621 ataaacagtt gactgccaac aaaagagcga ttgtttcatc atctgcgcta ggcatttgtt
    31681 ctttaattgc ttggtatttt tctgtcgcaa ccttagcgat ttcctccata aaaaggttgt
    31741 catgttcgct tgtcaaggtt aacgattttt tcccgaatgt aaatttgaat cgatttagat
    31801 ttgccataaa attcacctca cgatattata ccaaaattcg ctaattttgt cagtttttac
    31861 aaattttact gcttttgtgg tacaatagaa actatggcaa gtatcacact cacaccaagc
    31921 gaaaaggata ttcaagcttt tcttgaacac tatcaaacca gtctggctcc tagcaagaat
    31981 ccctatatcc gctacttttt gaaactacct caagcaacgg tttctatcta tacttctgga
    32041 aaaatcttgc ttcagggtga aggggctgaa aaatacgcca gtttctttgg ctatcaagct
    32101 gtagagcaaa ccagcggaca aaatcttcct ttaattggga cagatgaggt gggaaatggt
    32161 tcctactttg gtgggcttgc agttgtggct gcctttgtca cacctgacca gcacgacttt
    32221 ttacgaaaac tcggtgtggg ggattctaag actctgaccg accaaaagat ccgtcagatt
    32281 gctcctattc tcaaggaaaa aatccagcac caggcactcc ttctctcacc cagcaagtac
    32341 aacgaggtca tcggagaccg ctacaatgct gtttcggtta aggttgccct ccataatcag
    32401 gctatctatc tcctccttca aaaaggtgtt cagcctgaga aaattgtgat tgatgccttt
    32461 accagtgcta aaaattatga caagtacttg gcacaagaga ccaatcgttt cagcaatcct
    32521 atcagcttag aagaaaaggc tgagggcaaa tacttggctg tcgcagtttc ttctgtcatt
    32581 gcgcgtgatc tctttctgga aaatcttgaa aatctgggac gagaactggg ttatcagctt
    32641 ccaagtggag ctggaacggc ttctgacaag gtggctagcc agattttgca agcctatggt
    32701 atgcagggac tcaacttctg cgctaagcta cactttaaaa atactgaaaa agcgaaaaac
    32761 gcttagaaag gtaagttatg aatttattta aaaatttctt aaaagagtgg ggattattcc
    32821 tcctgattct gtcattacta gctttgagcc gtatcttttt ttggagcaat gttcgcgtag
    32881 aaggacattc catggatccg accctagcgg atggtgaaat cctctttgtt gttaagcacc
    32941 tccctattga ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacatcg
    33001 tcaagcgcgt gattggaatg cctggcgaca ccattcgtta cgaaaatgat aaactctaca
    33061 tcaatgacaa agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg
    33121 acaaactcca aagcacttac tcaggcaagg gctttgaagg aaataaagga actttcttta
    33181 gaagtatcgc tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta
    33241 gctttactgt tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg
    33301 acagccgcca cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct
    33361 tctggccaat cacccgtatc ggaacatttt aagaaaccta agaggccgag aatcaccaat
    33421 ctcagcctct tcttctatcg tgagaagtga ttgtttattg acaaatactc aatgaaaatc
    33481 aaagaacaaa ctaggaagct agccgtaggc tgcttaaaac agtgttttga ggttgcagat
    33541 ggaagctgac gtggtttgaa gatattttcg aagagtataa aataaaaaca atcccaactc
    33601 tcacctattc atgcaaagga attttatgga agtttatttt tcaggaacca ttgaacggat
    33661 tatttttgaa aatcccagca atttttatcg catcctcctc ctagaaatcg acgatacgga
    33721 cgcagaggat tttgatgact ttgaaatcat tgtcacagga accatggctg atgtaattga
    33781 gggcgaagac tatacttttt gggggcaaat tgtccagcac tccaagtatg gagaacaact
    33841 gcaaatcagt cgttatgatc gcgcaaaacc aactagtaag ggcttggtca agtacttttc
    33901 aagtagccat ttcaagggga ttggtctcaa gacagctcag aaaatcgtgg atacctatgg
    33961 cgaaaatacc attgacgaaa ttttgcaaca cccagaaaag ttagaaggca tcgcaggact
    34021 ctctgccaaa aatcgcgagg ctttcgtctc cactctccgt ctcaactacg gaacggagat
    34081 ggttttggcc aaactagcca actacggcat tcccaacaaa ctagcctttc agattcaaga
    34141 cttttacaag gaagaaaccc ttgatgtggt tgaaaattat ccctaccagc tggttgagga
    34201 tatcaagggt ttgggcttta ccattgctga ccaactagct gaggaactag gcatcgaaag
    34261 tcaggctcct gaacgcttcc gcgccggtct agttcacagt ctttttcagg cctgtatgga
    34321 aacaggggac acctatgttg aagcacggga tttgctggaa caaaccctta ctctccttga
    34381 gtcttcccgt cccgtagaac tagaccccag ccaagttgcc caagagctct cctacctgat
    34441 cgaagaagac aaggttcagc agattgatac caagatcttt gacaacagcc tctttttcgc
    34501 tgaggaaggc atccgcagtc acttggttcg tatccttgaa aaaggaaaac agaagagtca
    34561 tgatttagaa accattcaaa aacatatcac tactatcgag gaagagctgg gaattgagta
    34621 tgataacatt caaaaacagg ctatctgtga tgctatccag aataaggtct ttatcctgac
    34681 aggtggacct ggtactggta agacaactgt tatcaatggg atcatcgctg tttacgccct
    34741 gttagaggga cttgacctca ggaagaaaag caatctgccc attcttcttg ctgctccaac
    34801 tggacgagcc gctcgccgca tgaatgaatt gacaggtttg cctagcgcga ccatacaccg
    34861 ccacttggga atgacaggtg acgatgatac cagtcatctg gaagattacc tagatgctga
    34921 ctttatcatc gtggatgaat tctctatggt ggatacttgg ctggccaatc aactcttctc
    34981 caatatctct tctaacagta agatcctcat cgtaggtgac agtgatcagc taccttctgt
    35041 cagtcctgga caggttctag cggatctgct tcatattcct ttgattcctc agactcgctt
    35101 ggaaaaaatt tatcgacaaa gcgaagaatc aaccatcgtc accctagcta gtcagattcg
    35161 acagggcatc ttgccagctg atttcaccca aaaaaaagct gaccgttcct actttgaaat
    35221 tgctagtggc catattcctg ccaccattga aaaaatctta ggtgccgccc tcagaaatgg
    35281 tattcctgcc cgtgatatcc aagttctggc tcctatgtac cgagggacgg cagggattga
    35341 tgctatcaat cagctcatgc aagacctgct caatccccca caaaaagatc aactcagttt
    35401 tgaagttcct cagtgccact atcgtaaggg agacaaggtc attcatttgg ttaacgatgc
    35461 tgaaatcaat gtctttaatg gggatttagg agctatcaca gacctgattc ctggtaaata
    35521 caccgaatcg aaacaagacg agattgtcat tgattttgat ggtaatgaag tctcttaccc
    35581 ccgtaacgaa tggtacaaga ttcgcttggc ctatgccatg agtattcata agtctcaggg
    35641 aagtgagttc ccagttgtca tcctaccgat tactagtgct agccgacgta tgctggagcg
    35701 aaatctcatc tacacagcca ttacacgtgc caaaagcaaa ctcatcttac taggcgaatt
    35761 acaagccttc gactatgcta cccaacacat cggaactgcc cgaaaaacct atctgattga
    35821 acgcttcagt gatctactgg agaatgttga agaaaagcaa caagctgtct ctgaaacagt
    35881 cacatcaagt gcctctgaac aatcctacat cctaaccgaa gaaaactggg acagcattcc
    35941 agccatgatt gggattacag acacagacct caaagagatt tttggaaaat agtgcatcag
    36001 aaaaaccacc aattcaggtg ggttttctgt ttattaagat tattttactg ttgctgtgct
    36061 tgtaatcaat tcaacagctt ttttgatagt gatatcatgt ttcaacatgt cagctgaaag
    36121 caagttttga acttgtgcaa cttccatgtt gtagtctgct gccaattgct caacttcttt
    36181 ttggatttct tcttctgaag catcaaatcc ttcagctttg gcaactgctt cgataacaag
    36241 gttagtctta gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt cttcttgagt
    36301 agttccagtg atttggaagt acatgtcagg gttgatccct tgacgttgca agttcccaag
    36361 gaattcattt actgaacggt gaacttcttc gtggatcatt tcttctggaa gttctacgat
    36421 ttcagcattt tctacagctg tatcaattgc tgcaccttca actgcatctt tgtaagcttc
    36481 ttctttagca gcagccaatt ctttgcggta tttttctttc aagtcagcaa gtgtttcaac
    36541 ttcttcatca atgtcttttg caagttcatc gtcaagagct ggaacttctt tagcttttac
    36601 ttcgtggata gttgtcacga atttagcttc tttacctgca aggtcttctg cttggtagtc
    36661 ttctgggaat gttacgataa catcaacggt ttcgccagct gagtgaccta ccaattggtc
    36721 ttcgaaacca gggatgaatt gacctgaacc aagtccaagt gagaagtttt caccttttcc
    36781 accgtcaaat tcaacaccgt cgatagaacc aacgaagtcg atcacaacag tgtcgccgtt
    36841 ttcagcagca gcttccttga taaccaattc agccaggttg ttgcgttcgc gttcgatacg
    36901 ctcttcaaca tcagcgtcag ttacttcttt ttctacatca actgatactt caaggttttt
    36961 gtagtcaccc aattttactt caggttttgt aacgacttca gcagcgataa cccagtcttg
    37021 acctttttcc attgaagtta cgtcaatttt tggttgggca accacttcaa gaccagcttc
    37081 ttttacagct gcttcataag cgtttggcaa aagagcgttc ataacgtctt ggtaaagtga
    37141 tttttcacca aattttttat cgaagatagg acgtggaagg tgacctttac ggaaacctgg
    37201 aacattaaga gatttcttca ctgacttgaa gacacggtcc aattctggtt tgatttggtc
    37261 ttgagagata gtgaaagtca agacaccacg gtttgtttct ttgttttcaa atgatacaga
    37321 cattctgtca tttctcctta aaatttttta aatacagtct attataacat tttctataaa
    37381 taaaatctag actaatgcag ccaattatag acaacaagcc tttttcctaa ctaaaa
//
LOCUS       DAVLHB010000016        36840 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLHB010000016 DAVLHB010000000
VERSION     DAVLHB010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36840
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.016"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            371..598
                     /locus_tag="VXE36_000936"
     CDS             371..598
                     /locus_tag="VXE36_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779261.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VXE36_000937"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VXE36_000937"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0779262.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNDQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="VXE36_000938"
     CDS             4798..5250
                     /locus_tag="VXE36_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0779263.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5269..6606
                     /locus_tag="VXE36_000939"
     CDS             5269..6606
                     /locus_tag="VXE36_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0779264.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKYPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="VXE36_000940"
     CDS             6685..7569
                     /locus_tag="VXE36_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0779265.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="VXE36_000941"
     CDS             7569..8402
                     /locus_tag="VXE36_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0779266.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8409..8480
                     /locus_tag="VXE36_000942"
                     /pseudo
     CDS             8409..8480
                     /locus_tag="VXE36_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8597..9700
                     /locus_tag="VXE36_000943"
     CDS             8597..9700
                     /locus_tag="VXE36_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0779267.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            9874..10572
                     /locus_tag="VXE36_000944"
     CDS             9874..10572
                     /locus_tag="VXE36_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0779268.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            10591..12108
                     /locus_tag="VXE36_000945"
     CDS             10591..12108
                     /locus_tag="VXE36_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0779269.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            12233..13561
                     /locus_tag="VXE36_000946"
     CDS             12233..13561
                     /locus_tag="VXE36_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779270.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            13813..14679
                     /locus_tag="VXE36_000947"
     CDS             13813..14679
                     /locus_tag="VXE36_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0779271.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            14695..15534
                     /locus_tag="VXE36_000948"
     CDS             14695..15534
                     /locus_tag="VXE36_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0779272.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            15806..16258
                     /locus_tag="VXE36_000949"
     CDS             15806..16258
                     /locus_tag="VXE36_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0779273.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            16355..16699
                     /locus_tag="VXE36_000950"
     CDS             16355..16699
                     /locus_tag="VXE36_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779274.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            16983..17627
                     /locus_tag="VXE36_000951"
     CDS             16983..17627
                     /locus_tag="VXE36_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0779275.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            17796..18713
                     /locus_tag="VXE36_000952"
     CDS             17796..18713
                     /locus_tag="VXE36_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0779276.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            18731..19615
                     /locus_tag="VXE36_000953"
     CDS             18731..19615
                     /locus_tag="VXE36_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0779277.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(19631..20482)
                     /locus_tag="VXE36_000954"
     CDS             complement(19631..20482)
                     /locus_tag="VXE36_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0779278.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            20682..22739
                     /gene="pbp2b"
                     /locus_tag="VXE36_000955"
     CDS             20682..22739
                     /gene="pbp2b"
                     /locus_tag="VXE36_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0779279.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            22750..23346
                     /gene="recR"
                     /locus_tag="VXE36_000956"
     CDS             22750..23346
                     /gene="recR"
                     /locus_tag="VXE36_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0779280.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            23522..24565
                     /locus_tag="VXE36_000957"
     CDS             23522..24565
                     /locus_tag="VXE36_000957"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0779281.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            24649..26022
                     /locus_tag="VXE36_000958"
     CDS             24649..26022
                     /locus_tag="VXE36_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0779282.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            26009..26620
                     /locus_tag="VXE36_000959"
     CDS             26009..26620
                     /locus_tag="VXE36_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0779283.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            26711..27415
                     /locus_tag="VXE36_000960"
     CDS             26711..27415
                     /locus_tag="VXE36_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0779284.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            27634..29007
                     /gene="ftsA"
                     /locus_tag="VXE36_000961"
     CDS             27634..29007
                     /gene="ftsA"
                     /locus_tag="VXE36_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0779285.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            29024..30283
                     /gene="ftsZ"
                     /locus_tag="VXE36_000962"
     CDS             29024..30283
                     /gene="ftsZ"
                     /locus_tag="VXE36_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0779286.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            30288..30959
                     /locus_tag="VXE36_000963"
     CDS             30288..30959
                     /locus_tag="VXE36_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0779287.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            30969..31508
                     /locus_tag="VXE36_000964"
     CDS             30969..31508
                     /locus_tag="VXE36_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0779288.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            31508..31771
                     /locus_tag="VXE36_000965"
     CDS             31508..31771
                     /locus_tag="VXE36_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0779289.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            31768..32553
                     /locus_tag="VXE36_000966"
     CDS             31768..32553
                     /locus_tag="VXE36_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0779290.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            32562..33350
                     /gene="divIVA"
                     /locus_tag="VXE36_000967"
     CDS             32562..33350
                     /gene="divIVA"
                     /locus_tag="VXE36_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0779291.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            33698..36490
                     /locus_tag="VXE36_000968"
     CDS             33698..36490
                     /locus_tag="VXE36_000968"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0779292.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        11416 a         6502 c         8019 g        10903 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 attaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggaataa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg atcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ccccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcaag ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgcgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 tgaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
     4621 gaggttgtag ataagactga cgtatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4681 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagccg tttaggaact tatgtgggag taaatccaca ttttgcaaca
     4861 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     4921 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gatgctttgg ttccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aattttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaatatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aagtttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttgacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgat ctgaaaagct ctagcccaat
     6661 tttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtgttggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg ttattgcctt ctcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     7441 ctgggctggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca attttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     8401 aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgc tcaaagtaca
     8461 gctttgaggt tgcagataaa actgacgaag tcagtaacca tacgcacagt aaggcgacgt
     8521 tgacgcggtt tgaagagatt ttcgaagagt ataagttaaa attagaaagt ttattcaata
     8581 ataaaggaga aaaaacatgg ttaaatacgg tgttgttgga gcagggtatt ttggagctga
     8641 attggctcgc tacatgcaaa agaatgatgg agcagagatt actcttctct atgatccaga
     8701 taatgcagag gcgattgcag aagaattggg agcaaaagta gcaagttcct tagatgagtt
     8761 ggtttctagc gatgaagtag attgtgttat cgtcgcaact ccaaataatc ttcataagga
     8821 accggttatt aaggctgcac agcatggtaa aaatgttttc tgtgaaaaac caattgcgct
     8881 ttcttatcaa gattgtcgcg agatggtaga tgcgtgtaaa gaaaacaatg taacctttat
     8941 ggcaggacat attatgaatt tctttaatgg tgttcatcat gcaaaagaac tcattaatca
     9001 aggagttatc ggagacgttc tatattgtca tacagctcgt aatggttggg aagaacaaca
     9061 accgtcagtg tcatggaaaa aaattcgtga aaaatcaggt ggtcacttgt atcaccacat
     9121 ccatgaattg gattgcgttc aattccttat ggggggcatg cctgaaactg taaccatgac
     9181 aggtggaaat gtggcccatg aaggtgaaca tttcggtgat gaagatgata tgatttttgt
     9241 caatatggaa ttttctaata agcgttttgc cttgttagaa tggggttcag cttatcgttg
     9301 gggtgaacat tatgtcttaa tccaaggaag caaaggtgcc atccgcttag acttattcaa
     9361 ctgtaaagga actcttaagc tagatgggca agaaagctat ttcttgattc acgaatcgca
     9421 agaagaagat gatgatcgga ctcgtatcta tcatagtaca gagatggatg gagcaattgc
     9481 ttatggtaaa ccaggtaaac gtactccatt atggctatca tctgtcattg ataaagaaat
     9541 gcgctatctg catgagatta tggaaggagc cccagtatca gaagaatttg caaaactttt
     9601 gacaggtgaa gctgccctag aagcaattgc tactgcagat gcttgtaccc agtctatgtt
     9661 tgaagatcgc aaagtaaaat tgtcagaaat tgtaaaataa attttggtat tctcctattt
     9721 ataggtcgac ttgctcctct gaaagtactt ttagaggagc tgtttgactt tgctagtttt
     9781 tgaaactgaa atctattata ctacaaacta ttgaaagcgt tttaatttta aggtataata
     9841 atctcataga aataaagaaa aggaggaaag aggatgccac agattagcaa agaagccttg
     9901 attgagcaaa tcaaagatgg aatcatcgtt tcttgtcagg ctcttcctca tgaaccgctt
     9961 tatacagaag cgggaggggt gattcccttg ctggtcaaag cggctgagca aggtggagca
    10021 gtcggtatcc gagcaaacag tgttcgcgat atcaaggaaa ttaaggaagt cactaaactt
    10081 ccaatcattg ggattatcaa acgtgattat ccacctcagg aacccttcat cacggctact
    10141 atgaaagaag ttgatgaatt ggcagaactg gacatcgagg tgattgctct ggattgtacc
    10201 aagcgtgaac gctacgatgg tttggaaatt caagagttca ttcgtcaggt taaggagaaa
    10261 tatcctaatc agcttttgat ggctgatact agtatcttcg aagaagggct agcagctgta
    10321 gaagcaggaa ttgactttgt cggaacaacc ttatcaggct acacatccta cagtccaaaa
    10381 gtagacggtc cagattttga attgattaag aaactctgtg atgccggtgt agatgtcatt
    10441 gcagaaggaa aaattcatac accagaacaa gccaaacaaa tccttgaata tggagtgcga
    10501 ggcatcgttg ttggtggcgc cattactaga ccaaaagaga ttacagaacg cttcgttgct
    10561 agtcttaaat aagatgtgag agggagtttt atgtttaaag ttttacaaaa agttggaaaa
    10621 gcttttatgt tacctatagc tatacttcct gcagcaggtc tacttttggg gattggtggt
    10681 gcactttcaa acccaaccac gatagcaact tatccaatac tagacaatag tatttttcaa
    10741 tcaatattcc aagtaatgag ctctgcagga gaggttgtat tcagtaattt gtcactactt
    10801 ctctgtgtgg gattatgtat tggcttagcg aaacgagata aaggaaccgc tgcgttagca
    10861 ggagtaactg gttacttagt tatgactgca acgatcaaag ctttggtaaa actttttatg
    10921 gcagaaggat ctgcaattga tactggagtt attggagcat tagttgtcgg aatagttgcc
    10981 gtatatttgc acaaccgata taacaatatt caattacctt ccgctttagg attctttgga
    11041 ggttcacgct tcgttcctat tgttacatcg ttctcttcta tcttgattgg ctttgtcttc
    11101 tttgttattt ggccaccttt ccaacaactt cttgtttcta caggtggata tatttctcag
    11161 gcgggtccaa ttggaacttt tctatatgga tttttaatga gactttctgg agcagtaggc
    11221 ttacatcata taatttaccc tatgttttgg tatactgaac ttggtggtgt tgaaactgtt
    11281 gcaggacaaa cagtggttgg agctcaaaaa atattttttg ctcaattagc cgatccggcc
    11341 cattctggat tatttacaga aggaacaagg ttttttgcag gtcgtttctc aacaatgatg
    11401 ttcggtttac cggctgcctg tttagcgatg taccatagtg ttcctaaaaa tcgtcgtaaa
    11461 aaatacgcgg gtttgttttt tggagttgct ttaacatctt ttattaccgg tattacagaa
    11521 ccaattgaat ttatgtttct attcgtcagt ccggttctat atgttgttca cgcattcctt
    11581 gatggtgtta gcttctttat tgcagacgtc ttaaatattt caataggaaa cacattttca
    11641 ggaggtgtaa tcgatttcac tttatttgga attttgcagg ggaacgctaa gacgaattgg
    11701 gttcttcaga ttccaattgg acttatttgg agtgttttgt attatattat ttttagatgg
    11761 ttcattactc aattcaacgt tctaacgcca ggacgaggag aagaagtaga ttctaaagaa
    11821 atttctgaat ccgcagattc aacttcaaat actgcagatt atttaaaaca ggatagccta
    11881 caaattatca gagccttggg tggatcaaat aatatagaag atgtagatgc ttgtgtgaca
    11941 cgtttacgtg tagctgtaaa agaagttaat caagttgata aagcactttt aaaacaaatt
    12001 ggtgcagttg atgtcttaga agtgaagggt ggcattcaag caatatatgg agcaaaagca
    12061 atcttatata aaaatagtat taatgaaatt ttaggtgtag atgattaagt acttactgac
    12121 ttaataaaaa acagaggaga gtgatggatg agtaggatga aatgaaatcg catacaagaa
    12181 ataaagaact cattatccaa gttggatacg cttattacat aggagaatac aaatgaaatt
    12241 tagaaaatta gcttgtacag tacttgcggg tgctgcggtt cttggtcttg ctgcttgtgg
    12301 caattctggc ggaagtaaag atgctgccaa atcaggtggt gacggtgcca aaacagaaat
    12361 cacttggtgg gcattcccag tatttaccca agaaaaaact ggtgacggtg ttggaactta
    12421 tgaaaaatca atcatcgaag cgtttgaaaa agcaaaccca gatataaaag tgaaattgga
    12481 aaccatcgac ttcaagtcag gtcctgaaaa aatcacaaca gccatcgaag caggaacagc
    12541 tccagacgta ctctttgatg caccaggacg tatcatccaa tacggtaaaa acggtaaatt
    12601 ggctgagttg aacgacctct tcacagatga atttgttaaa gatgtcaaca atgaaaacat
    12661 cgtacaagca agtaaagctg gagacaaggc ttatatgtat ccgattagtt ctgccccatt
    12721 ctacatggca atgaacaaga aaatgttaga agatgctgga gtagcaaacc ttgtaaaaga
    12781 aggttggaca actgatgatt ttgaaaaagt attgaaagca cttaaagaca agggttacac
    12841 accaggttca ttgttcagtt ctggtcaagg gggagaccaa ggaacacgtg cctttatctc
    12901 taacctttat agcggttctg taacagatga aaaagttagc aaatatacaa ctgatgatcc
    12961 taaattcgtc aaaggtcttg aaaaagcaac tagctggatt aaagacaatt tgatcaataa
    13021 tggttcacaa tttgacggtg gggcagatat ccaaaacttt gccaacggtc aaacatctta
    13081 cacaatcctt tgggcaccag ctcaaaatgg tatccaagct aaacttttag aagcaagtaa
    13141 ggtagaagtg gtagaagtac cattcccatc agacgaaggt aagccagctc ttgaatacct
    13201 tgtaaacgga tttgcagtat tcaacaataa agacgacaag aaagtcgctg catctaagaa
    13261 attcatccag tttatcgcag atgacaaaga gtggggacct aaagacgtag ttcgtacagg
    13321 tgctttccca gtccgtactt catttggaaa actttatgaa gacaaacgca tggaaacaat
    13381 cagcggctgg actcaatact actcaccata ctacaacact attgatggtt ttgctgaaat
    13441 gagaacactt tggttcccaa tgttgcaatc tgtatcaaat ggtgacgaaa aaccagcaga
    13501 tgctttgaaa gccttcactg aaaaagcgaa cgaaacaatc aaaaaagcta tgaaacaata
    13561 gtccttagtt attctataaa aagtagtttt ttaaagaacc taagagtgta tacccccttt
    13621 tccctctaca cagatagtgt aagaaaaggg ggcttttgtt taaaatgtaa gaaactgtca
    13681 cgaaattaaa atgaagttct tacataagcg aaccataaaa aatttcattt tgattttaaa
    13741 acagttcaag aaagtcaaaa aattattcta tttgaaagag aggtgccgac tgtgaaagtc
    13801 aataaaatcc gtatgcggga aacagtgatt tcctacgctt tcctagcacc agtattattc
    13861 ttctttgtca tctttgtgtt ggctccgatg gtgatgggct tcattacaag tttctttaac
    13921 tactcaatga ctaaatttga gtttgtgggc ttagataact atatccgtat gtttaaagat
    13981 cctgtcttta caaaatctct gattaacaca gttattttgg ttattggatc tgtaccagtt
    14041 gttgttctat tctcactctt tgtagcatct cagacctatc atcaaaatgt cattgccaga
    14101 tccttctacc gtttcgtctt cttccttcct gttgtaacgg gtagtgttgc cgtgacagtt
    14161 gtttggaaat ggatttatga cccactatca gggattctaa actttgtcct taagtcaagc
    14221 cacatcatca gccaaaacat ttcttggttg ggagataaaa actgggcatt gatggcgatt
    14281 atgattattc tcttgaccac ttcagttggt cagcccatca tcctttatat cgctgccatg
    14341 gggaatattg acaattcact ggttgaagcg gcgcgtgttg atggtgcaac tgagtttcaa
    14401 gttttttgga agattaaatg gccaagcctt cttccaacaa ctctttatat tgcaatcatc
    14461 acaacaatta actcattcca gtgtttcgcc ttgattcagc ttttgacatc tggtggtcca
    14521 aactactcaa caagtacctt gatgtactac ctttacgaaa aagccttcca attgacagaa
    14581 tacggctatg ccaacacaat tggtgtcttc ttggcagtca tgattgctat cgtaagcttt
    14641 gttcaattta aagtacttgg aaacgacgta gaatactaaa gaaaggagac agctatgcaa
    14701 tctacagaaa aaaaaccatt aacagccttt actgttattt caacaatcat tttgctcttg
    14761 ttgactgtgc tgttcatctt tccattctac tggattttga caggggcatt caaatcacaa
    14821 cctgatacaa ttgttattcc tcctcagtgg ttccctaaaa tgccaaccat ggaaaacttc
    14881 caacaactca tggtgcagaa ccctgccttg caatggatgt ggaactcagt atttatctca
    14941 ttggtaacca tgttcttagt ttgtgcaacc tcatctctag caggttatgt attggctaaa
    15001 aaacgtttct atggtcaacg cattctattt gctatcttta tcgctgctat ggcgcttcca
    15061 aaacaagttg tccttgtacc attggtacgt atcgtcaact tcatgggaat ccacgatact
    15121 ctctgggcag ttatcttgcc tttgattgga tggccattcg gtgtcttcct catgaaacaa
    15181 tttagtgaaa atattcctac agagttgctt gaatcagcta aaatcgacgg ttgtggtgag
    15241 attcgtacct tctggagtgt agccttcccg attgtgaaac cagggtttgc agcccttgca
    15301 atctttacct tcatcaatac ttggaatgac tacttcatgc aattggtaat gttgacttca
    15361 cgtaacaatt tgaccatctc acttggggtt gcgaccatgc aggctgaaat ggcaaccaac
    15421 tatggtttga ttatggcagg agctgccctt gctgctgttc caatcgtcac agtcttccta
    15481 gtcttccaaa aatccttcac acagggtatt actatgggag cggtcaaagg ataatactct
    15541 gagaaaatct cttcaaacta cgtcagcgtc accttgccat acttaagtat tgcctgcggt
    15601 tagcttccta gtttgttctt caattttcat tgagtatagg aaaatcaatc tatcaagata
    15661 cagaagtata ttttatagat ttagagaata tagaggttat aagtgtctac aaaatggagg
    15721 gtatgcagtt actttatgaa gttttgtcag acacttataa acttaagaat ggttttagtt
    15781 aactatcaga aacgaaggaa agagtatgat ttttgacgat ttgaaaaaca tcacctttta
    15841 caaagggatt catcccaatt tagacaaggc tatcgactat ctctaccaac atcgtaaaga
    15901 ttcattcgaa ttaggaaagt atgagattga tggagataaa gtctttctag ttgttcagga
    15961 aaatgtcctc aatcaagttg agaataatca atttgaacac cataagaact atgcagattt
    16021 gcatttgctg gtagaaggac atgaatattc gagctacggt tcacgtatca aagacgaggc
    16081 agtagcattc gacgaagcga ctgacattgg ctttgttcat tgtcatgaac actacccact
    16141 cttgttgggt tatcataatt ttgcgatttt cttcccaggt gagccacatc agccaactgg
    16201 ctatgcaggt atggaagaaa aggttcgaaa atatctcttt aaaattttga ttgattaaaa
    16261 ataggatgaa ttgttttttt gtaaagcttt gacaatactc taccatgaaa ttgatctttg
    16321 tgaggtatag aaatgagaat aaaatattta aaaattggta tcttctaagc atgctgcaag
    16381 agctagtttc ttagatggac aggggattac agttgatgag atgtcctgga taattaatgg
    16441 cattgtgaat gcattgattg gtagatacat aaaattaggt acttatgcag ctaagtatgg
    16501 tattagtata gcacgctcga tcttaagtag ggcagctgca actgcagcag caagagtagg
    16561 attactgacc aagatttctg gatggatttt acgagtagct gtgaatgtag ctgatgtata
    16621 tggtaatttt gccaacaata ttgctgcagc ttgggatgca tatgataaaa ttcctaacaa
    16681 tggtcgtata aacttttaaa atgcgagaat gaaagcactt tgtatttttt tattgaatat
    16741 gttagcttgg acagtgcttg caatgataat tcgtggaggg ctagatggat ttgataggca
    16801 tacttggagt actattttaa ttgcttcgct gttcggggta tatgattata agcccataga
    16861 taaaaataga aaaaagtcca aaagaaaaaa gaaaaaatag atttgttcat ggtagggact
    16921 tatgaaagct ttactgacaa aaaagaaaac agtttacaaa gaaaaatgat ggaggagcaa
    16981 acatggcaca aaaaggagta agccttatca aggcagcatt tgatacagat aactttctca
    17041 tgcgttttag tgagaaggtc ttggacatcg tgacagccaa tcttcttttt gtcgtctctt
    17101 gtttgcccat cgtgacgatt ggagtggcta aaatcagcct ctacgagacc atgttcgaag
    17161 ttaagaagag cagacgggtg cctgttttta aaatctatct aagatctttc aagcaaaatc
    17221 tgaaactagg tcttcagtta ggtctgcttg agttgggcat tgtttcatta agcctcctag
    17281 atctttatct cttttggggt caaacagctc tgccctttca attgctgaaa gctatttgtc
    17341 taggcattct gattttcctt acgattgtga tgttggctag ctatccaatc gcggcacgtt
    17401 atgatttaac ttggaaagaa attcttcaaa aaggattgat gttggctagt tttaactttc
    17461 cttggttctt cctcatgtta gccattcttg tcctcattgt gatggttctt tatctgtctg
    17521 ccttcagtct actcttaggt ggctcagtct tcctgctttt tgggtttgga ctattggtct
    17581 ttatccagac tggattgatg gagaaaattt tcgcaaaata ccaataggag ccttatttct
    17641 gaaactactt tcaaaggctc caaacgctat tctataagcg agaaactaaa atctaagtgt
    17701 ctataagata ttgaaagcct tttcggtaaa gtgtatacta aagaagtaaa gaaaaatctg
    17761 ctttagcaga aaataaaaat aataggagaa aatctatgtc agatttgaaa aaatacgaag
    17821 gtgtcattcc agccttctac gcatgttatg atgagcaagg agaagtaagt ccagagcgta
    17881 cgcgtgcctt ggttcaatac ttcattgata aaggtgttca aggtctttat gtcaatggtt
    17941 cttctggtga atgtatctac caaagcgttg aagatcgcaa gttgattttg gaagaagtca
    18001 tggcggtagc caaaggtaaa ttgaccatta ttgcccatgt tgcttgcaat aatactaaag
    18061 atagtatgga acttgctcgc catgctgaaa gcttgggagt agatgctatt gcaacgattc
    18121 caccaattta cttccgcttg ccagaatact cagttgccaa atactggaac gatattagtt
    18181 ctgcagctcc aaacacagac tacgtgattt acaacattcc tcaattggca ggggttgctt
    18241 tgactccaag cctttacaca gaaatgttga aaaatcctcg tgttatcggt gttaagaact
    18301 cttctatgcc agttcaagat atccaaacct ttgtcagcct tggcggggaa gaccatattg
    18361 tctttaacgg tccagatgaa cagttcctag gtggccgcct catgggtgct aaggctggta
    18421 tcggtggtac ttatggtgct atgccagaac tcttcttgaa actcaatcag ttgattgcgg
    18481 ataaggacct agaaacagcg cgtgaattgc agtatgctat caacgcaatc attggtaaac
    18541 tcacttctgc tcatggaaat atgtacggtg tcatcaaaga agtcttgaaa atcaatgaag
    18601 gcttgaatat tggatctgtt cgttcaccat tgacaccagt aactgaagaa gatcgtccag
    18661 ttgtagaagc ggctgcagcc ttgattcgtg aaaccaagga gcgcttcctc taatctaaaa
    18721 ggaggtattt atgacatact acgttgcaat tgatatcggt ggaactaaca tcaagtatgg
    18781 tttggttgat caagaggggc aacttcttga atcgcatgaa atgccaactg aggcgcataa
    18841 gggtggacct catatcttac aaaagaccaa agatatcgta gctagttatt tagaaaaagg
    18901 cccagtagca ggtgttgcca tatcttctgc tgggatggtg gatccggata agggtgagat
    18961 tttctatgct gggccgcaaa tccctaacta cgcaggcacc cagttcaaaa aggaaatcga
    19021 agaaagcttt actattcctt gtgagattga aaatgatgtc aactgtgcag gtcttgctga
    19081 ggcagtatct ggttcaggca agggagcaag tgtgacactt tgcttgacca ttggaacagg
    19141 tatcggtggt tgcttgatta tggataggaa agtcttccat ggttttagta attcagcctg
    19201 tgaagtcggg tatatgcata tgcaggatgg agcttttcaa gacttggctt ctacaacagc
    19261 tttagtgaaa tatgtagctg aagcccatgg agaagatgtt gatcagtgga atggccgacg
    19321 tatctttaag gaagctactg aaggaaacaa aatctgcatg gaaggtattg accgtatggt
    19381 tgactatcta ggaaaaggtc tggcaaatat ttgctacgtt gccaatccag aagtggttat
    19441 tcttggtggt ggtatcatgg ggcaagaggc tatcctcaaa cctaagatcc gcacagcctt
    19501 gaaagaggct ttggtaccaa gtttagcaga aaaaacacga ttagaatttg cccatcacca
    19561 aaatacagca gggatgttgg gtgcatatta tcattttaag acaaaacaat cctagtttgg
    19621 ctcagccaaa ctaggatttt cttacacgtt tttgtctacg atagccgttg agttttttat
    19681 tttcccagta gctattaaag attttttcct tgctttcgcg attgatttcc aaaaagtagg
    19741 cataaatcaa atcgataaag aagagcatag gaagttgagc ggatattcgt tggatatagg
    19801 agggttggct gtgggtggct acaagaacag tctctgtata ggtctggcta tctttattgg
    19861 gaacacttgt aaagagtaca gtctttgccc ccatctcctt ggcatctaat agactatcta
    19921 aaatagaagg agttgagcct gaaagtgaga agcccagtac tagacaattt tcatccatga
    19981 tgctggttgt ccaggcaaag ccgtcttggt ctgtcaaagc ttcgcagacc acacctagtc
    20041 gcataaaacg taatttcatt tcacgggcga cgaggccaga actccctgtt ccgaagaagt
    20101 agatacgctc agcatcttcg attagctggg caattcgttc tagttggatt tcgtcaatca
    20161 agtcttgtgt ttgttccctc atgttgctat aacttctgag gactcgtttg gtcagtggac
    20221 tgtgcttgga gacttggttg gcttgatttt ctgcctgatg ttggtattgg aaaataaatt
    20281 ctcggtagcc agtaaagcca cactttttag caaagcgggt caaagcagct tgagaaatat
    20341 gtaatttttg ggtgacttgt tgagaagata aatcatctgt aatcgtttca gcttgcaaaa
    20401 aatagcgagc gatttcttgt tctaggtctg tcatttcttc aaaatgtgaa tcaatgatag
    20461 ttgcgatatc tggtttgtcc atagggaaag ctcctttaca tgagtcatac tggaagacta
    20521 gatcagggaa tagtcacact tcattataac acataatata aggatagata aataaaaacg
    20581 catctctgtt ttaaaaacga aaaaatcgaa aaagcttctc tcttttccat aattttctac
    20641 tcaaattgtg gtacaattaa gagtaagatt ttaagttaga aatgagactg atttgtatga
    20701 gaaaatttaa cagccattcg attccgattc ggcttaattt attgttttca atcgtcattt
    20761 tactctttat gaccattatt ggtcgtttgt tgtatatgca ggttttgaac aaggattttt
    20821 acgaaaaaaa gctagcctca gctagtcaga ccaagattac aagcagttca gcccgtgggg
    20881 aaatttatga tgctagtgga aaacctttgg tagaaaatac gttaaagcag gttgtttcct
    20941 ttacgcgtag caataaaatg acagctacag acttaaaaga aacagctaaa aagttactga
    21001 cttatgtgag catcagttct ccaaatttga cagaacgcca gctggcggat tactatttgg
    21061 ctgatcctga aatctataaa aaaacagtgg aagctctccc aagcgagaaa cgcttggatt
    21121 cagatggcaa tcgtctatcc gaatcagaac tgtataacaa tgcggtcgat agtgtacaaa
    21181 cgagtcaact aaactataca gaggatgaaa agaaagaaat ctatcttttt agtcagttaa
    21241 atgctgttgg aaactttgcg acaggaacca ttgcgacaga tcctctaaat gattctcagg
    21301 tggctgttat tgcctctatt tcaaaggaga tgcctggcat tagtatttct acttcttggg
    21361 atagaaaggt tttggaaact tccctttctt ctatagttgg gagtgtatcc agtgaaaaag
    21421 ctggtctccc agcggaagaa gcagaagcct atcttaaaaa aggctattct ctaaatgatc
    21481 gtgtaggaac ctcctatttg gaaaagcaat atgaagagac cttacaagga aaacgctcgg
    21541 taaaagaaat ccatctggat aaatatggca atatggaaag cgtggataca attgaggaag
    21601 gtagtaaggg aaacaatatc aaactgacca ttgatttggc tttccaagat agcgtggatg
    21661 ctttactgaa aagttatttc aattccgagc tagaaaatgg tggagccaag tattctgaag
    21721 gtgtctatgc agtcgccctt aacccaaaaa caggtgcggt tttgtctatg tcagggatta
    21781 aacatgactt gaaaacggga gagttgacgc ctgattcctt gggaacggta accaatgtct
    21841 ttgttccagg ttcggttgtc aaggcggcga ccatcagctc aggttgggaa aatggagtct
    21901 tgtcaggaaa ccagaccttg acagaccagt ccattgtctt ccaaggttca gctcccatca
    21961 attcttggta tactcaggct tacggttcat tccctatcac agcggtccaa gctctggagt
    22021 attcatcaaa tacctatatg gtccaaacag ccttaggtct tatggggcaa acctatcaac
    22081 ccaatatgtt tgtcggcacc agcaatctag agtctgctat ggagaaactg cgttcaacct
    22141 ttggcgaata tggcttgggt actgcgacag gaattgacct accagatgaa tctactggat
    22201 ttgttcccaa agagtatagc tttgctaatt acattactaa tgcctttggg cagtttgata
    22261 actatacgcc gatgcagttg gctcagtatg tagcaactat tgcaaataat ggtgttcgtg
    22321 tggctcctcg tattgttgaa ggcatttatg gtaataatga taagggagga ctgggtgact
    22381 tgattcagca actgcaaccg acagagatga ataaggtcaa tatatccgac tccgatatga
    22441 gcatcttgca ccaaggtttt tatcaggttg cccatggtac tagtggattg acaactggac
    22501 gtgccttttc aaatggtgcc ttggtatcca ttagcggaaa aacaggtaca gccgaaagct
    22561 atgtggcaga tggtcagcaa gcaaccaata ccaatgcggt ggcctatgcc ccatctgata
    22621 atccccaaat cgctgtcgca gtggtctttc ctcataatac caatctaaca aatggtgtag
    22681 gaccttccat tgcgcgtgac attatcaatc tgtatcaaaa ataccatcca atgaactaga
    22741 aaggaaatta tgctttatcc aacacctatt gccaagttga ttgacagtta ttctaagtta
    22801 ccaggtatcg ggattaagac ggctacgcgt ctggcctttt atacgattgg gatgtctgct
    22861 gatgatgtca atgaatttgc aaaaaatctc ctttctgcta agagagaatt gacatattgt
    22921 tctatttgtg gacgtttgac agacgacgat ccttgttcta tctgtactga ttcgactcgt
    22981 gaccagacaa caattttagt tcttgaggat agtagagatg tggcagccat ggaaaatatc
    23041 caagaatacc atggactcta tcatgtcctg catggcctca tttctcctat gaatggtatc
    23101 agtccggacg atatcaatct taagagcctt atgactcgtc ttatggatag tgaggtttca
    23161 gaagtgattg tggcgactaa tgctacagcg gatggtgaag cgacctccat gtatctttca
    23221 cgtttgctca agccggctgg tatcaaggtt acgcgtctag cacgaggtct cgctgtggga
    23281 gcggacattg agtatgcgga cgaagtgaca ctcttacgag cgattgaaaa tcggacagag
    23341 ttgtaagtgt aggcaaattt acgaactcca ttcatttata aaaaatcaaa gaggctgaaa
    23401 atcgttccta tcggcctctt tttgtatagt gtgatgagta gaatcaggtt caagttttaa
    23461 aaaaccaagc aaatatgata tactaaagag cgagtattct agtagaatta ggacaaataa
    23521 tatgaaacaa acgattattc ttttatatgg tggacggagt gcggaacgcg aagtctctgt
    23581 cctttcagct gagagtgtca tgcgtgcggt caattacgac cgtttcacag tcaagacttt
    23641 ctttatcagt cagtcaggtg actctatcaa aacgcaggaa tttagtcatg ctccggggca
    23701 agaagaccgt ctcatgacca atgaaaccat tgattgggat aagaaagttg caccaagtgc
    23761 tatctacgaa gaaggtgcag tggtctttcc agtccttcac gggccaatgg gagaagatgg
    23821 ctctgttcaa ggattcttgg aagttttgaa aatgccttac gttggttgca acattttgtc
    23881 atcaagtctt gccatggata aaatcacgac taagcgtgtt ctggaatctg ctggtattgc
    23941 ccaagttcct tatgtggcta tcgttgaagg cgatgatgtg actgctaaaa tagctgaagt
    24001 ggaagaaaaa ttggcttatc cagtcttcac taagccgtca aacatggggt ctagtgtcgg
    24061 tatttctaag tctgaaaacc aagaagaact ccgtcaagcc ttaaaacttg ccttccgata
    24121 tgacagccgt gtcttggttg agcaaggagt gaatgcccgt gaaattgagg ttggcctctt
    24181 gggtaactac gatgtcaaga gcacgctacc tggagaagtt gtcaaggacg ttgcctttta
    24241 tgactacgat gccaagtata ttgataacaa ggttactatg gatattcctg ccaaaatcag
    24301 tgatgatgtg gtggctgtca tgcgtcaaaa tgcagaaaca gccttccgtg ccattggtgg
    24361 ccttggtcta tctcgttgcg atttcttcta tacagataag ggagagattt ttctcaacga
    24421 gctcaatacc atgccaggtt tcacccagtg gtctatgtac ccactacttt gggaaaatat
    24481 ggggatcagc tacccagaac taatcgagcg tttggttgac cttgccaagg aaagttttga
    24541 caagcgcgaa gcgcatttga tataaaatga aagagagggt agaagccaga accatcactg
    24601 caaggtgact agagttctcg gacttcagcc ctttttaaag gagtagaaat gaaattaaca
    24661 atccatgaaa ttgcccaagt tgttggagcc aaaaatgata tcagtatctt tgaggacact
    24721 cagttagaaa aagctgagtt tgatagtcgt ttgattggaa ctggagattt atttgtgcca
    24781 cttaaaggtg cgcgtgatgg ccatgacttt attgaaacag cctttgaaaa tggtgcagca
    24841 gtaaccttgt ctgagaaaga ggtctcaaat catccttaca ttttagtaga tgatgttttg
    24901 acagcctttc aatccctagc atcctactat cttgaaaaaa cgactgttga tgtctttgct
    24961 gttacaggtt caaatggcaa gacaacgact aaggatatgt tggcgcattt actgtcaaca
    25021 agatacaaga cctacaaaac acaaggcaat tacaataatg agattggcct tccttacaca
    25081 gttcttcata tgcctgaagg aacagaaaag ttggttttgg agatgggaca ggatcacttg
    25141 ggagatattc atctcttgtc tgaattggct cgtccaaaaa cagccatcgt gaccttggtt
    25201 ggagaagctc atttggcctt tttcaaagat cgttctgaga ttgctaaagg aaaaatgcaa
    25261 attgcagacg gaatggcttc aggttccttg cttttagcgc cggctgaccc tatcgtagag
    25321 gactatttgc caattgataa aaaggtggtt cgttttggtc aaggagcaga gctggaaatt
    25381 actgacttgg ttgagcgtaa ggacagtctg acctttaagg ctaatttctt ggaacaagcc
    25441 cttgatttgc cagtaactgg caagtacaat gcgacaaatg ctatgattgc atcctatgtt
    25501 gccttgcaag aaggagtttc agaggagcaa attcgtttgg cattccaaca tcttgaattg
    25561 acgcgtaacc gtaccgagtg gaagaaagca gccaatggag cagatatcct gtcagatgtt
    25621 tacaatgcca atccaactgc tatgaaactg attttagaga ctttctctgc cattccagcc
    25681 aatgaaggtg gcaagaaaat tgcagtgttg gcggatatga aggagcttgg tgaccagtct
    25741 gttcaacttc ataatcagat gattttgagc ctctccccag atgtgcttga tatcgttatt
    25801 ttctatggag aagatattgc tcagttggct caattggcca gtcaaatgtt tccaatcggc
    25861 cacgtttact acttcaagaa aacagaagac caggatcaat ttgaagacct agtcaagcag
    25921 gttaaggaaa gccttggagc ctatgaccaa atcttgctaa aaggttctaa ctctatgaat
    25981 ctagccaaat tggtagaaag tttagaaaat gaatgcaagt gattttgcta agtatcttca
    26041 aagaatgatt gctcttacag atactggact aacctttaca aaggatccgt ttgaccgtga
    26101 gcgctacgaa gacttgcgaa gtctgttatc tgaaatgttg aatcaggtat cagaccttga
    26161 tgcagacgaa gtggcagaac tcttgaaacc gacctccgct tatgcgactc ctttaatgga
    26221 cgtccgtgct tggatagttg aggatgaaaa aatttgtctg gttaggggac aaggagagaa
    26281 tgattgggct ttgccaggtg gctttggcga ggtcggttat tcaccaactg aaaatattct
    26341 caaggaaatt gaagaagaaa ccggttttaa agccaaagtt gaacgactac tagctgtttt
    26401 tgataccaat cgtttccaac tacagagcaa acaatatgca aagtttgttt ttgaatgtaa
    26461 gcttctcgat ggacaatttc aagaaaatca agaaatcgct gaccttcaat tttttgcaat
    26521 tgaccaactg ccgaatttat ctgaaaaacg cattaccaag gagcaaatag agcttctttg
    26581 gcaggtttat caaggtcata gggggcaata tcttgactaa gaagatgatt atcgtatttc
    26641 taaatccatt tttaacaact agcatggtat aataatatgc aggaaaattt tgaattatga
    26701 ggaagactag atgaatttat gggatatttt ctttacgact caggcaaccg agccgcccaa
    26761 atttgacctt ttttggtatg ttagcctatt tacgctctta gccttaacct tttatacagc
    26821 ccatcgctat cgtgaaaata aggtttacca acgatttttc caaatcttgc agactgttca
    26881 gttaatcctt ctttatggtt ggtactgggt caatcatatg ccactgtcag aaagcctacc
    26941 cttttaccat tgccgtatgg ctatgtttgt ggtactcttg cttcctggtc aatccaaata
    27001 taaacaatac tttgcattat tgggaacatt tgggacatta gcagcctttg tttatccagt
    27061 gccagatgct tacccttttc cacatatcac cattctatcc tttatctttg gtcatttagc
    27121 actcttgggg aactctctag tttatctatt gagacagtat aatgcgcgat tgctggatgt
    27181 gaagggaatt tttctcatga cctttgccct aaatgccttg atttttgtgg tcaatttggt
    27241 gacaggtggc gattacggat ttttgacaaa accgccattg gttggggatc acggtctagt
    27301 agctaattat ttacttgttt caattgtgct ggtagctact atcagtttga ctaagaaaat
    27361 cttagaattc tttttagctc aagaagcaga aaaaatgatt gcaaaggaag cttaacacag
    27421 agctttcttt tttgctctta gagagttttt acaagcagct tataaaataa gaatttctga
    27481 atagacaaac tcaaaaaatg gctgggaaat ttaggaaaaa agcaagcacg attaaatttt
    27541 ttgtgttata atattttgtg aatagctatg cctatgttta gctatggaat aatacgaagt
    27601 gcgaaacttg gaagatagag aggaagcgat gtaatggcta gagaaggctt ttttacaggt
    27661 ctagatattg gaacaagctc tgtcaaggtg cttgtggccg agcagagaaa tggtgaatta
    27721 aatgtaattg gcgtgagtaa tgccaaaagt aaaggtgtaa aggatggaat tattgttgat
    27781 attgatgcag cagcaactgc tatcaagtca gccatttccc aagcggaaga aaaggcaggc
    27841 atttcgatta aatcagtgaa tgtcggcttg cctggtaatc ttttgcaggt agaaccaact
    27901 caggggatga ttccagtaac atctgatact aaggaaatta cggatcaaga tgttgaaaat
    27961 gttgtcaaat cagctttgac aaagagtatg acacctgacc gtgaagtcat tacctttatt
    28021 cctgaagaat ttattgtgga tggtttccaa gggattcgtg acccacgtgg catgatgggg
    28081 gttcgccttg aaatgcgtgg tttgctttat acaggacctc gtactatctt gcacaatttg
    28141 cgtaagacgg ttgagcgtgc aggtgttcag gttgaaaatg ttatcatttc accactagca
    28201 atggttcagt ctgttttgaa cgaaggggaa cgtgaatttg gtgctacagt gattgatatg
    28261 ggggcaggtc aaacgactgt cgctacaatc cgtaatcaag aactccagtt cacacatatt
    28321 ctccaagaag gtggagatta tgtaactaaa gatatctcca aggttttgaa aacctctcgc
    28381 aaattagcgg aaggcttgaa actgaattac ggggaagcct atccgcctct tgcaagcaaa
    28441 gaaaccttcc aagtagaggt tattggagaa gtagaagcag tcgaagtgac ggaagcctac
    28501 ttgtcagaaa ttatttctgc acgaatcaag cacatccttg aacaaatcaa gcaagaatta
    28561 gatagaaggc gtctattgga cctccctggt ggtattgtct taatcggtgg gaatgccatt
    28621 ttaccaggta tggttgagct tgctcaggaa gtctttggcg tccgtgtcaa gctttatgtc
    28681 ccaaatcaag ttggtatccg taatccagcc tttgcgcatg tgattagttt atcagaattt
    28741 gcgggtcaat taacagaagt taatcttttg gctcagggag cgataaaagg tgagaatgac
    28801 ttaagtcatc agccaattag ttttggtggg atgctgcaaa aaacagctca gtttgtacaa
    28861 tcaacgcctg ttcaaccagc tcctgctcca gaagtagagc cggtggcgcc tacagaacca
    28921 atggcggatt tccaacaagc ttcacaaaat aaaccgaaat tagcagatcg tttccgtggc
    28981 ttgatcggaa gcatgtttga cgaataaaga ggaaaaataa attatgacat tttcatttga
    29041 tacagctgct gctcaagggg cagtgattaa agtaattggt gtcggtggag gtggtggcaa
    29101 tgccatcaac cgtatggtcg acgaaggtgt tacaggcgta gaatttatcg cagcaaacac
    29161 agatgtacaa gcattgagta gtacaaaagc tgagactgtt attcagttgg gacctaaatt
    29221 gactcgtggt ttgggtgcag gaggtcaacc tgaggttggt cgtaaagccg ctgaagaaag
    29281 cgaagaaaca ctgacggaag ctattagtgg tgccgatatg gtcttcatca ctgctggtat
    29341 gggaggaggc tctggaactg gagctgctcc tgttattgct cgtatcgcca aagatttagg
    29401 tgcgcttaca gttggtgttg taacacgtcc ctttggtttt gaaggaagta agcgtggaca
    29461 atttgctgta gaaggaatca atcaacttcg tgagcatgta gacactctat tgattatctc
    29521 aaacaacaat ttgcttgaaa ttgttgataa gaaaacaccg cttttggagg ctcttagcga
    29581 agcggataac gttcttcgtc aaggtgttca agggattacc gatttgatta ccaatccagg
    29641 attgattaac cttgactttg ccgatgtgaa aacggtaatg gcaaacaaag ggaatgctct
    29701 tatgggtatt ggtatcggta gtggagaaga acgtgtggta gaagcggcac gtaaggcaat
    29761 ctattcacca cttcttgaaa caactattga cggtgctgag gatgttatcg tcaacgttac
    29821 tggtggtctt gacttaacct tgattgaggc agaagaggct tcacaaattg tgaaccaggc
    29881 agcaggtcaa ggagtgaaca tctggctcgg tacttcaatt gatgaaagta tgcgtgatga
    29941 aattcgtgta acagttgttg caacgggtgt tcgtcaagac cgcgtagaaa aggttgtggc
    30001 tccacaagct agaactgcta ctaactaccg tgagacagtg aaaccagctc attcacatgg
    30061 ctttgatcgt cattttgata tggcagaaac agttgaattg ccaaaacaaa atccacgtcg
    30121 tttggaacca actcaggcat ctgcttttgg tgattgggat cttcgccgtg aatcgattgt
    30181 tcgtacaaca gattcagtcg tttctccagt cgagcgcttt gaagccccaa tttcacaaga
    30241 tgaagatgaa ttggatacac ctccattttt caaaaatcgt taagtaaatg aatgtaaaag
    30301 aaaatacaga acttgttttt cgagaagttg cagaggctag tctgagtgct aatcgagaga
    30361 gtggttcggt ctctgtcatt gcagttacca agtatgtaga tgtaccgaca gcggaagcct
    30421 tgcttccgct aggtgttcat catatcggtg aaaatcgtgt agataagttt ctggaaaaat
    30481 atgaagcttt aaaagatcga gatgtgactt ggcatttgat tggtaccttg caaagacgta
    30541 aggtgaaaga tgtcattcaa tacgttgatt atttccatgc attggactca gtaaagctag
    30601 caggggaaat tcaaaaaaga agtgaccgag tcatcaagtg tttccttcaa gtaaatattt
    30661 ctaaagaaga aagcaaacac ggtttttcga gagaggaact gctggaaatc ttgccagagt
    30721 tagccagact agataagatt gaatatgttg gtttaatgac gatggcacct tttgaggcta
    30781 gcagtgagca gttgaaagag attttcaagg cgacccaaga tttacaaaga gaaattcaag
    30841 agaaacaaat tccaaatatg cctatgaccg agttaagtat gggaatgagt cgtgattata
    30901 aagaagcgat tcaattcggt tccacttttg ttcgtatagg tacatcattt tttaagtagg
    30961 agagaaccat gtctttaaaa gatagattcg atagatttat agattatttt acggaggatg
    31021 aggattcaag tctcccttat gaaaaaagag atgagcctgt gtttactcca gtaaattctt
    31081 cacaggaacc ggctctccca atgaatcaac cttcacagtc ggctggtaca aaagagaaca
    31141 atatcaccag acttcatgca agacaacagg aattggcaaa tcagagtcag cgtgcaacgg
    31201 ataaggtcat tatagatgtt cgttatccta gaaaatatga ggatgcaaca gaaattgttg
    31261 atttattggc aggaaacgaa agtatcttga ttgattttca gtatatgaca gaggtgcagg
    31321 ctcgtcgttg tttggactat ttggatggag cttgtcatgt tttagctgga aatttgaaaa
    31381 aggtagcttc taccatgtat ttgttgacac cagtgaatgt tattgtaaat gttgaagata
    31441 tccgtttacc agatgaagat caacagggtg agttcggttt tgatatgaag cgaaatagag
    31501 tacgataatg atttttttaa ttcgtatgat ttataatgca gtggatattt actccctgat
    31561 tttggtagcc ttcgctgtca tgtcttggtt tccaggtgcc tacgaatcca gtttaggtcg
    31621 ttggattgta gcgttggtga aaccagtact tgctcccttg caacgcctgc ctttacagat
    31681 agcgggtctt gatttatctg tttgggtcgc gattgttttg gttcgatttt taggagaaaa
    31741 cctagtgcgt tttctggcga tgataggatg aataaaggga tttatcagca tttctccata
    31801 gaagatcgtc catttcttga caagggaatg gaatggataa agaaggtaga agatagctat
    31861 gctccttttt taactccttt tatcaatcct catcaggaga agctattaaa gattttggcc
    31921 aaaacctatg gtcttgcttg tagcagtagt ggggaattcg tctcgagtga gtatgttcga
    31981 gttttattat acccagatta tttccaacca gagttttcag attttgaaat atctctccag
    32041 gaaattgtgt attccaataa atttgaatat ttaacgcatg ctaagatttt agggacagtc
    32101 atcaatcaat tagggattga acggaaactt tttggagata tcctagtaga tgaagaacgg
    32161 gcgcagatta tgattaatca gcagtttctt cttctctttc aagatggact aaagaaaatt
    32221 ggtcgtatac ctgtttcgct ggaggaacgt cctttcaccg agaaaataga taagctagaa
    32281 cagtatcgag aactggattt atctgtgtct agttttcgat tagatgttct tttatcaaat
    32341 gttttgaaac tatctaggaa tcaagcaaac cagttgattg aaaagaaact tgtccaagta
    32401 aattatcatg tggtagacaa atcagattac actgttcaag ttggagactt gattagtgtg
    32461 agaaaatttg gtcgcttgag attacttcaa gataagggac aaacgaaaaa agagaagaaa
    32521 aaaataaccg tccagttatt attaagtaag tgaggaatag aatgccaatt acatcattag
    32581 aaataaagga caagactttt ggaactcgat tcagaggttt tgatccagaa gaagtcgatg
    32641 aatttttaga tattgtggtt cgtgattacg aagatcttgt gcgtgcgaat catgataaaa
    32701 atttgcgtat taagagttta gaagagcgtt tgtcttactt tgatgaaata aaagattcat
    32761 tgagccagtc tgtattgatt gcccaggata cagctgagcg agtgaaacag gcggcgcatg
    32821 aacgttcaaa caatatcatt catcaagcag agcaagatgc gcaacgcttg ttggaagaag
    32881 ctaaatataa ggcaaacgag attcttcgtc aagcaactga taatgctaag aaagtcgctg
    32941 ttgaaacaga agaattgaag aacaagagcc gtgtcttcca ccaacgtctc aaatctacaa
    33001 ttgagagtca gttggctatt gttgaatctt cagattggga agatattctc cgtccaacag
    33061 ctacttatct tcaaaccagt gatgaagcct ttaaagaagt ggttagcgaa gtacttggag
    33121 aaccgattcc agctccaatt gaagaagaac caattgatat gacacgtcag ttctctcaag
    33181 cagaaatgga agaattacaa gctcgtattg aggtagccga taaagaattg tctgaatttg
    33241 aagctcagat taaacaggaa gtggaaactc caactcctgt agtgagtcct caagttgaag
    33301 aagagcctct gctcatccag ttggcccaat gtatgaagaa ccagaagtag ctccagtgca
    33361 tccgacaggt ccaacaccag ctacagaaac tgttgattca gcaccgggat ttgaagcacc
    33421 gcaagaatct gttacaattt tataagaaat attctgagaa caatatctta tccttatatt
    33481 cccagcgagc aggagatggt gtgagtcctg cattccctat cgataagatt atcctctcaa
    33541 aaactcaagt ctgaagctag taagatttga cgttccccac gttacgggat aagagggaga
    33601 aagactaaaa ctttttccga ataaaggtgg taccacgatt ttcgtccttt ttggaagtcg
    33661 tggtttttaa tttgttatta tttataaagg agataccatg aaactcaaag acacccttaa
    33721 tcttgggaaa actgaattcc caatgcgtgc aggccttcct accaaagagc cagtttggca
    33781 aaaggaatgg gaagatgcaa aactttatca acgtcgtcaa gaattgaacc aaggaaaacc
    33841 tcatttcacc ttgcatgatg gccctccata cgctaacgga aatatccacg ttggacatgc
    33901 tatgaacaag atttcaaaag atatcattgt tcgttctaag tctatgtcag gattttacgc
    33961 accatttatt cctggttggg atactcatgg tctgccaatc gagcaagtat tgtcaaaaca
    34021 aggtgtcaaa cgtaaagaaa tggacttggt tgagtacttg aaactttgcc gtgagtacgc
    34081 tctttctcaa gtagataaac aacgtgaaga ttttaaacgt ttgggtgttt ctggtgactg
    34141 ggaaaatcca tatgtgacct tgactcctga ctatgaagca gctcaaattc gtgtatttgg
    34201 tgagatggct aataagggtt atatctaccg tggtgccaag ccagtttact ggtcatggtc
    34261 atctgagtca gcccttgctg aagcagagat tgaataccat gatttggttt caacttccct
    34321 ttactatgcc aacaaggtaa aagatggcaa aggagttcta gatacagata cttatatcgt
    34381 tgtctggaca acgactccat ttaccatcac agcttctcgt ggtttgacgg ttggtgcaga
    34441 tattgattac gttttggttc aacctgctgg tgaagctcgt aagtttgtcg ttgctgctga
    34501 attattgact agcttgtctg agaaatttgg ctgggctgat gttcaagttt tggaaactta
    34561 ccgtggccaa gaactcaacc acatcgtaac agaacaccca tgggatacag ctgtagaaga
    34621 gttggtaatt cttggtgacc acgttacgac tgactctggt acaggtattg ttcatacagc
    34681 ccctggtttt ggtgaggacg attacaatgt tggtattgct aataatcttg aagtcgcagt
    34741 gactgttgat gaacgtggta tcatgatgaa gaatgctggt cctgaatttg aaggtcaatt
    34801 ctatgaaaag gtagttccaa ctgttattga aaaacttggt aacctccttc ttgcccaaga
    34861 agaaatctct cactcatatc catttgactg gcgtactaag aaaccaatca tctggcgtgc
    34921 agttccacaa tggtttgcct cagtttctaa attccgtcaa gaaatcttgg acgaaattga
    34981 aaaagtgaaa ttccactcag aatggggtaa agtccgtctt tacaatatga tccgtgaccg
    35041 tggtgactgg gttatctctc gtcaacgtgc ttggggtgtt ccacttccta tcttctacgc
    35101 tgaagatggt acagctatca tggtagctga aactattgaa cacgtagctc aactttttga
    35161 agaacatggt tcaagcattt ggtgggaacg tgatgccaaa gacctcttgc cagaaggatt
    35221 tactcatcca ggttcaccaa acggcgagtt caaaaaagaa actgatatca tggacgtttg
    35281 gtttgactca ggttcatcat ggaatggagt ggtggtaaac cgtcctgaat tgacttaccc
    35341 agccgacctt tacctagaag gttctgacca ataccgtggt tggtttaact catcacttat
    35401 cacatctgtt gccaaccatg gcgtagcacc ttacaaacaa atcttgtcac aaggttttgc
    35461 ccttgatggt aaaggtgaga agatgtctaa atctcttgga aataccattg ctccaagcga
    35521 tgttgaaaaa caattcggtg ctgaaatctt gcgtctctgg gtaacaagtg ttgactcaag
    35581 caatgacgtg cgtatctcta tggatatttt gagccaagtg tctgaaactt accgtaagat
    35641 tcgtaacact cttcgtttct tgattgccaa tacatctgac tttaacccag ctcaagatac
    35701 agtcgcttac gatgagcttc gttcagttga taagtacatg acgattcgct ttaaccagct
    35761 tgtcaagacc attcgtgatg cctatgcaga ctttgaattc ttgacgatct acaaggcctt
    35821 ggtgaacttt atcaacgttg acttgtcagc cttctacctt gattttgcca aagatgttgt
    35881 ttacattgaa ggtgccaaat cactggaacg ccgtcaaatg cagactgtct tctatgacat
    35941 tcttgtcaaa atcaccaaac tcttgacacc aatccttcct cacactgcgg aagaaatctg
    36001 gtcatatctt gagtttgaaa cagaagactt cgtccaattg tcagaattac cagaagttca
    36061 aacttttgct aaccaagaag aaatcttgga tacatgggca gccttcatgg actttcgtgg
    36121 acaagcacaa aaagccttgg aagaagctcg taatgcaaaa gttatcggta aatcacttga
    36181 agcacacttg acagtttatc caaatgaagt tgtgaaaact ctactcgaag cagtaaacag
    36241 caatgtagca caacttttga tcgtgtctga gttgaccatc gcagaaggac cagctccaga
    36301 agctgccctt agcttcgaag atgtagcctt cacagttgaa cgtgctgctg gtgaagtatg
    36361 tgaccgttgc cgtcgtatcg acccaacaac agcagaacgc agctaccagg cagttatctg
    36421 tgaccactgt gcaagcatcg tagaagaaaa ctttgcggaa gcagtcgcag aaggatttga
    36481 agagaaataa gattgaaaag tctaggcaaa attcaatttg agaagaaaag acaactaatt
    36541 ttatagtcta ttaaacgcat tgtatcacgt ttttgaacac ctgatatgat gcgtttttta
    36601 tttattttaa aaatttgcga ggtatgactt tttatactca acaagaatca aagagaaact
    36661 tagcaagcta acagtagtaa gataaaatag gaatttgata ttagggataa gattggtaaa
    36721 tagtgtaata tttttacaac aataaattta tatagttatt tttggtttct gaaaagtatt
    36781 atattttatt tcatattata caaattttta ttttataata tcagaaaata ctttttttaa
//
LOCUS       DAVLHB010000017        36461 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLHB010000017 DAVLHB010000000
VERSION     DAVLHB010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.017"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(36..884)
                     /locus_tag="VXE36_000969"
     CDS             complement(36..884)
                     /locus_tag="VXE36_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0779293.1"
                     /translation="MNTNLKPKLQRFASATSFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            1036..1314
                     /locus_tag="VXE36_000970"
     CDS             1036..1314
                     /locus_tag="VXE36_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779294.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            1316..3379
                     /locus_tag="VXE36_000971"
     CDS             1316..3379
                     /locus_tag="VXE36_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0779295.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKREFDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEKDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3457..4713)
                     /locus_tag="VXE36_000972"
     CDS             complement(3457..4713)
                     /locus_tag="VXE36_000972"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0779296.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAIRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            4855..7320
                     /locus_tag="VXE36_000973"
     CDS             4855..7320
                     /locus_tag="VXE36_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0779297.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEEKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            7385..8296
                     /locus_tag="VXE36_000974"
     CDS             7385..8296
                     /locus_tag="VXE36_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0779298.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIVLIILPMIFLSIEEAKESR"
     gene            8526..9224
                     /gene="dapD"
                     /locus_tag="VXE36_000975"
     CDS             8526..9224
                     /gene="dapD"
                     /locus_tag="VXE36_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0779299.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            9292..10422
                     /locus_tag="VXE36_000976"
     CDS             9292..10422
                     /locus_tag="VXE36_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0779300.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            10434..10973
                     /locus_tag="VXE36_000977"
     CDS             10434..10973
                     /locus_tag="VXE36_000977"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0779301.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            10957..11634
                     /locus_tag="VXE36_000978"
     CDS             10957..11634
                     /locus_tag="VXE36_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0779302.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(11701..12600)
                     /gene="galU"
                     /locus_tag="VXE36_000979"
     CDS             complement(11701..12600)
                     /gene="galU"
                     /locus_tag="VXE36_000979"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0779303.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(12622..13638)
                     /locus_tag="VXE36_000980"
     CDS             complement(12622..13638)
                     /locus_tag="VXE36_000980"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0779304.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            13850..14290
                     /locus_tag="VXE36_000981"
     CDS             13850..14290
                     /locus_tag="VXE36_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0779305.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(14413..14829)
                     /locus_tag="VXE36_000982"
     CDS             complement(14413..14829)
                     /locus_tag="VXE36_000982"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0779306.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(14897..15547)
                     /gene="phoU"
                     /locus_tag="VXE36_000983"
     CDS             complement(14897..15547)
                     /gene="phoU"
                     /locus_tag="VXE36_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0779307.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(15562..16314)
                     /gene="pstB"
                     /locus_tag="VXE36_000984"
     CDS             complement(15562..16314)
                     /gene="pstB"
                     /locus_tag="VXE36_000984"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0779308.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(16316..17131)
                     /gene="pstA"
                     /locus_tag="VXE36_000985"
     CDS             complement(16316..17131)
                     /gene="pstA"
                     /locus_tag="VXE36_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0779309.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(17124..17987)
                     /gene="pstC"
                     /locus_tag="VXE36_000986"
     CDS             complement(17124..17987)
                     /gene="pstC"
                     /locus_tag="VXE36_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0779310.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(18105..18980)
                     /locus_tag="VXE36_000987"
     CDS             complement(18105..18980)
                     /locus_tag="VXE36_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEV0779311.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAIVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(19147..20478)
                     /locus_tag="VXE36_000988"
     CDS             complement(19147..20478)
                     /locus_tag="VXE36_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0779312.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(20479..21186)
                     /locus_tag="VXE36_000989"
     CDS             complement(20479..21186)
                     /locus_tag="VXE36_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0779313.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(21270..21746)
                     /locus_tag="VXE36_000990"
     CDS             complement(21270..21746)
                     /locus_tag="VXE36_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0779314.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            21753..22280
                     /locus_tag="VXE36_000991"
                     /pseudo
     CDS             21753..22280
                     /locus_tag="VXE36_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22595..24286)
                     /locus_tag="VXE36_000992"
     CDS             complement(22595..24286)
                     /locus_tag="VXE36_000992"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0779315.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            24422..24868
                     /gene="argR"
                     /locus_tag="VXE36_000993"
     CDS             24422..24868
                     /gene="argR"
                     /locus_tag="VXE36_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0779316.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            24919..27453
                     /gene="mutS"
                     /locus_tag="VXE36_000994"
     CDS             24919..27453
                     /gene="mutS"
                     /locus_tag="VXE36_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0779317.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            27600..29294
                     /gene="patA"
                     /locus_tag="VXE36_000995"
     CDS             27600..29294
                     /gene="patA"
                     /locus_tag="VXE36_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0779318.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(29624..29887)
                     /locus_tag="VXE36_000996"
                     /pseudo
     CDS             complement(29624..29887)
                     /locus_tag="VXE36_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            30085..31851
                     /gene="patB"
                     /locus_tag="VXE36_000997"
     CDS             30085..31851
                     /gene="patB"
                     /locus_tag="VXE36_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0779319.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            31990..32679
                     /locus_tag="VXE36_000998"
     CDS             31990..32679
                     /locus_tag="VXE36_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0779320.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            32683..32862
                     /locus_tag="VXE36_000999"
     CDS             32683..32862
                     /locus_tag="VXE36_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779321.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            32849..34198
                     /locus_tag="VXE36_001000"
     CDS             32849..34198
                     /locus_tag="VXE36_001000"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0779322.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            34322..35782
                     /locus_tag="VXE36_001001"
     CDS             34322..35782
                     /locus_tag="VXE36_001001"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0779323.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            35796..36227
                     /locus_tag="VXE36_001002"
     CDS             35796..36227
                     /locus_tag="VXE36_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0779324.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
     gene            36351..36422
                     /locus_tag="VXE36_001003"
     tRNA            36351..36422
                     /locus_tag="VXE36_001003"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36384..36386,aa:Glu,seq:ttc)
BASE COUNT        10647 a         6994 c         8038 g        10782 t
ORIGIN      
        1 tacggcaagg cgacgttgac gtggtttgaa gagtattaga atgctttccc aaccaaaatc
       61 tctgcttcga tggtaatctc tgtcagttgg ctccagtcaa tcttgctctg gtcaacgtga
      121 aagaggagag gagtcatact gagtagggct tggagttgtt ctgctgtgat agtcttagtc
      181 agagaggcag tttgactaga taggatggta aagtgttcct ggaaatgctc cttgatatct
      241 tggttagaat actccttgtt tgtcagctgg tcctgtactc tttgacggat ttctttgagg
      301 tgattttcag ttgggataac ctttatcaag ataccgtctt tggataaaac gcgacgaaat
      361 tctccatagt tggcaggtga gaagatatca agcagaatat ccatgttagc gtcttttata
      421 ggaagtcgtg ccaagtcgcc aacgaaccaa ttgactgccc agttgggttc acttttagca
      481 gcgatttgga ctgaatcttt ggagatgtca aaggcataga aagttttttc agagtgactt
      541 tcttgtagtt tgcgagaata gaatccttca ccacaaccga tatccaaaat tgttgtggta
      601 gtttttgagc ttgcaagcaa gtcagataca gcatctaaga tagcttggta aaagccggct
      661 tctaggattt gttgacggtt ttgaaaattt tccttgtcat agttagcaga ttgcttgatt
      721 tgaggtgcta gattgacata gccaaatttc gccaagtcaa aagaatgacg gttgcagcac
      781 ttgaaattag tctctaacag agtcagattt tcttgacaga taggacaggc aaaggaagtc
      841 gcagaagcaa aacgctgaag tttgggcttg agatttgtat tcatagttta agtgtatcaa
      901 aagaggcaaa tgaaagcaac tttaggaata agtagatggg agattcagta gaaataaaac
      961 taattctcca atttatagaa tgaaattgct tttatatcta aattgctata taataatgat
     1021 aaggaggaaa taagtatgtt aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct
     1081 tcattatttt tgggtggtgt cgcatttggt acccttggtt tgaaaatctt agcaagtaag
     1141 gaagctaaaa aaggttattc taaagctttg gctaaggctt acaagttgaa agacgagcta
     1201 gatgcatctg tttctgttgt gaagcaacat ggagacgatg tcttgcaaga tgccaaatat
     1261 ttgtacgagc aagagaaaaa agaagagcaa ttagatagcc ttataggtga ataatatgtc
     1321 ttttaaagtg ctacatagag gataccaaca tatccgacta tcatcttctt tttcacttac
     1381 cttggatatt caagactatc ttcgttcctt ggcgagagat gaaaagggga ttgagtctat
     1441 ccagttttac atggatcaac agcactttac tctacgcata aaagaaggct tttctgtatt
     1501 agataatgca gaagcctttt taaaaagaat tgataaaggg aaagtttctg agttgatgac
     1561 tcttcccatt cgtagagaag agagtgctta ttctattgtt tcaggtgcag cggttaagcg
     1621 tgtacttttt cgtagttttg tgccgtatcc tattcgctat atatggactt gttatcaggc
     1681 tttgggttat attagagaag cctatcaaac actagcgcgt aaggaactaa cgatggaagt
     1741 cttggactgt tcggctattt tattgtcttt gtttatgaac caatccaaga cagctagcaa
     1801 tatcatgttt atgcttgatt tggggaatca tttagatcag tggtccttga aaaaaactgc
     1861 aacagattta gaacagagtc ttcttgcaaa agagagcgat gtattcctag tacagggcga
     1921 tacggttgtt agtatcaaga gttccgatgt tcaaatagga gatgtcttga tcttatctca
     1981 aggaaatgaa attctgtttg atggacaagt agtttcaggt ttaggtatgg tcaacgaaag
     2041 ttccttgaca ggagagagtt ttccagttga aaaaagagag tttgatttgg tttgtgcaaa
     2101 tacagtatta gaaactggag agttacgcat tcgtgtaaca gataatcaga tgaacagccg
     2161 tattttacag ctgattgagt tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg
     2221 ctatttcatc aagatggcgg ataaagtcgt caaatataat ttcttggggg ctgggctgac
     2281 ttacctattg acaggttctt tttctaaggc tatttctttc ctattggtcg atttctcctg
     2341 cgctttgaaa atctctactc ctgtagctta tttgacagtt atcaaggagg ggttgaaccg
     2401 tgaaatggtg attaaggatg gagatgttct ggagaaatat ctggaagttg atactttctt
     2461 gtttgataag acaggaacaa tcacaactag ttatcctata gttgaaaagg tgttaccttt
     2521 tggagactat agtgagaaag atattctcag aatcagtgcc tgtcttgagg aacacattta
     2581 tcatcctatt gctaatgcca tcgtcaagca agctgagata gagggaattg aacatgagga
     2641 aatgcatggg aaactccaat atatcgcaag caaggggatc aaatctcata tagatggcca
     2701 accagttctt attgggaatt atgtcttgat gcaggatgag cagattcata tcagttcaga
     2761 acaaaatgct ttaattgaag agtacaagag tcactacaat ctcttattct tggcttatca
     2821 aaatgaattg attggaatgt tctgcattca tactcctttg agaaaagaag caaaaacagc
     2881 cttggataaa cttaaggcac aggggaaaaa attgattctg gcaacaggag acaccttgat
     2941 taggacagag gaattagtca aagatttgcc ctttgatcag gtctatacag acttgaaacc
     3001 tgatgggaaa tttgagttag tagagaaact gcagaaagca ggtcacacta tcttgatggt
     3061 tggagatgga ttgaatgact cagcggcttt aactctatca gatatcggtg tggtgatgaa
     3121 tgagagtgca gatatttcta agcagatgag tgatatctta ttgttagata atcgtttgga
     3181 tttcttccaa gagttggatt cgttatcatc atctttgcaa acactcatca agaaaaatat
     3241 tcaagatacc gttgtcgtaa atagtagttt gattggcttt ggcttattta attggttcag
     3301 tccttcaaat ctctctatct tacataatct aacaaccttg cgcattgtct tgcgtagctt
     3361 gtctattaaa aatagataga tgagagttat taacagcaaa aaggagttac ctttctcgag
     3421 gttaactcct ttgtttatag ataaatgttg aatagtttag taagtcaata caaagtattt
     3481 tttcttccca cgacggataa cagtcagttc attttctaac ttatcagcgt cactcaagac
     3541 atagtcaagg tcttggatgc ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc
     3601 acgggcttgg cgttttgagt taactatacc agatgagacg agcagttcca cgatattgtt
     3661 gttttcgtct gcctgtactt ggtagtttgg cacaccacga agtccttgtt tgagctcttt
     3721 gacagaaagg tttttgatgt ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt
     3781 gtaggcttct tctccgtgaa caagtgtaac aacttcacga gccaagactt tttgagccaa
     3841 gcgttcgtgt ggcgctgctt caaattgttt acgaatatct tcaatctcat caagtgacaa
     3901 gaaagtaaag attttcaaga agcgaatagc gtcagcgtcc atcacgttca tccagaattg
     3961 gtacatttcg tatggagaag tcttttcggg attgagccag acggcatttc cttctgattt
     4021 accaaatttt ttaccagttg catctgtgat tagtggaaca gtgataacgt gaccagtctt
     4081 gtccgcctta cgacgaagca attcggtacc agctgtcata tttccccact ggtcagaacc
     4141 accgatttga agagtgacat tatggtcttg gttaaggacg aagaagtcgt acccttgcat
     4201 gatttggtaa gcgaactcag tgtaagaaat tcctgtttcg atccgttttt taacagattc
     4261 cttactcatc atgtagttga ccgtgaagta ttttccaatg tcacggagga agtcaatgaa
     4321 gctgatgctg ccaaaccagt cgtagttgtt gaccatgaca gccttgtttt cgccattttc
     4381 aaagtcaaga aaacgagaaa gttgtccttg gatagacttg acccagccat ctactgtgtc
     4441 ttttgtttgg agactacgtt cagcatcttt gaaggacgga tctccgatga gacctgtagc
     4501 accgccaacg agcgcataag gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat
     4561 tgcgacaagg tggcctaggt gaaggctgtc agcagttgga tcgtagccag tataataaga
     4621 aacttgacct tcttctaggg ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa
     4681 accacgctct tttagctcat caaaaatgtg catgtgtctt ttctcctttt taaaattatt
     4741 gtttctacct attgtatcac aaacttgggc aatagcctag cagaataggg aagaaagtgg
     4801 ctattttatt gaaaatttcc cttttgtggt ataatagata aagtgaggaa atccatgcaa
     4861 aatcaattaa atgaattaaa acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat
     4921 aaaaaatcag ctagacctgg caagaaaggt tcaagtacca aaaaatctaa aaccttagat
     4981 aagtcagcca ttttcccagc tattttactg agtataaaag ccttatttaa cttactcttt
     5041 gtactcggtt ttctaggagg aatgttggga gttgggattg ctttggggta cggagtggcc
     5101 ttatttgaca aggttcgggt gcctcagaca gaagaattgg tgaatcaggt caaggacatc
     5161 tcttctattt cagagattac ctattcggac gggacggtga ttgcttccat agagagtgat
     5221 ttgttgcgca cttctatctc atctgagcaa atttcggaaa atctgaagaa ggctatcatt
     5281 gcgacagaag atgaacactt taaagaacat aagggtgtag tacccaaggc ggtgattcgt
     5341 gcgaccttgg ggaaatttgt aggtttgggt tcctctagtg ggggttcaac cttgacccag
     5401 caactaatta aacagcaggt ggttggggat gcgccgacct tggctcgtaa ggcggcagag
     5461 attgtggatg ctcttgcctt ggaacgcgcc atgaataaag atgagatttt aacgacctat
     5521 ctcaatgtgg ctccctttgg ccgaaataat aagggacaga atattgcagg ggctcggcaa
     5581 gcagctgagg gaattttcgg tgtagatgcc agtcagttga ctgttcctca agcagcattt
     5641 ttagcaggac ttccacagag tcccattact tactctcctt atgaaaatac tggggagttg
     5701 aagagtgatg aagacctaga aattggctta agacgggcta aggcagttct ttacagtatg
     5761 tatcgtacag gtgcattaag caaagacgag tattctcagt acaaggatta tgaccttaaa
     5821 caggactttt taccatcggg cacggttaca ggaatttcac gagactattt atactttaca
     5881 actttggcag aagctcaaga acgtatgtat gactatctag ctcagagaga caatgtctcc
     5941 gctaaggagt tgaaaaatga ggcaactcag aagttttatc gagatttggc agccaaggaa
     6001 attgaaaatg gtggttataa gattactact accatagatc agaaaattca ttctgccatg
     6061 caaagtgcgg ttgctgatta tggctatctt ttagacgatg gaacaggtcg tgtagaagta
     6121 gggaatgtct tgatggacaa ccaaacaggt gctattctag gctttgtagg tggtcgtaat
     6181 tatcaagaaa atcaaaataa tcatgccttt gataccaaac gttcgccagc ttctactacc
     6241 aagcccttgc tggcctacgg tattgctatt gaccagggct tgatgggaag tgaaacgatt
     6301 ctatctaact atccaacaaa ctttgctaat ggcaatccga ttatgtatgc taatagcaag
     6361 ggaacaggaa tgatgacctt gggagaagct ctgaactatt catggaatat ccctgcttac
     6421 tggacctatc gtatgctccg tgaaaagggt gttgatgtca agggttatat ggaaaagatg
     6481 ggttacgaga ttcctgagta cggtattgag agcttgccaa tgggtggtgg tattgaagtc
     6541 acagttgccc agcataccaa tggctatcag accttagcta ataatggagt ttatcatcag
     6601 aagcatgtga tttcaaagat tgaagcagca gatggtagag tggtgtatga gtatcaggat
     6661 aaaccggttc aagtctattc aaaagctact gcgacgatta tgcagggatt gctacgagaa
     6721 gttctatcct ctcgtgtgac aacaaccttc aagtctaacc tgacttcttt aaatcctact
     6781 ctggctaatg cagattggat tgggaagact ggtacaacca accaagacga aaatatgtgg
     6841 ctcatgcttt cgacacctag attaacccta ggtggctgga ttgggcatga tgataatcat
     6901 tcattgtcac gtagagcagg ttattctaat aactctaatt acatggctca tctggtaaat
     6961 gcgattcagc aagcttcccc aagcatttgg gggaacgagc gctttgcttt agatcctagt
     7021 gtagtgaaat cggaagtctt gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa
     7081 gaaaaagaag tagaggtcac aggttcgact gttaccagct attgggctaa taagtcagga
     7141 gcgccagcga caagttatcg ctttgctatt ggcggaagtg atgcggatta tcagaatgct
     7201 tggtctagta ttgtggggag tctaccaact ccatccagct ccagcagttc aagtagtagt
     7261 tctagcgata gcagtaactc aagtactaca cgaccttctt cttcaagggc gagacgataa
     7321 ttctctaaat gaagtggcca atcaatggat tgccactttt ttcctttcgt gttacaataa
     7381 gggtatgaat cagtatcaga aaaagattgt taacggaaaa atttattcgc tcctatccgg
     7441 cttaatatgg ggaatctgtg gaattttagg agagtacttc tttactcatt atcaggtgtc
     7501 ttcgggctgg attacctcta tgcgtttgac actggcaggg agtcttgtac tcatttggtc
     7561 tgcaatacaa ttaaaatcgc aagtgctaga tatttggcga gacaagaaaa attacctgcc
     7621 ctttttagcc tatgctattt tggggatttt ttcagttcag tattttttct atctctgtgt
     7681 agaatactca aatgctacga cagcaactat tttacagttt attagccctg tctttatcct
     7741 cttttacaat cgcttggttt atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt
     7801 ggttgccatg ctgggtgttt gcttgatggc gacaaaggga gatctctctc agttatccat
     7861 gacgccgcta gctcttataa caggtttgct gagtgccatg ggtgttatgt ttaatgttat
     7921 cttgccccaa ccttttgcta agcgttatgg ttttgttcct acggttgggt gggggatgat
     7981 tttggcaggt ttgtttagca atgtcctctc gccggtttat cagctttcct ttactcttga
     8041 tatttggagt atcttgattt gcctcattat cgctttcttt ggaacggctt ttgctttttt
     8101 catttccatg aaggctgtgt ccttggtttc tcctttggtg gtttccgtta tcagtgccag
     8161 tgaacctctc tcttctgctc tcttgagtgt tttgttctta ggattagtag tggattggtc
     8221 cctccttcta gctatagtct tgattatttt acccatgata tttttgtcta tagaagaagc
     8281 gaaagaaagt agataaaaag tcttttctta attctaaaag tgtgctatac tagaatagtc
     8341 aataaaacac ggggagatag ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc
     8401 ttttaccgac agcacgtttt atctcacaac cctaaaaaat catacctaaa aacagacaaa
     8461 aaggtttcaa atttgaggcc ttttttggta gaataggtat cattataacg aaccaggagg
     8521 cacctatgac tgctacaaaa atgaacgctc aagaaattat ccaatttatc gccaatgctg
     8581 aaaagaaaac cagtgtcaaa gtaacctttg aggggcaact cgcaactgct gtgcctagct
     8641 ctgttgtcaa actaggaaat gtcctattcg gagactggaa ggacgtggct ccgcttcttg
     8701 aaggtttggt agaaaatcaa gattatgttg tcgagcaaga tgctcgtaat tctgcagttc
     8761 ctttgctaga taagcgtgct atcaacgctc gtatcgagcc aggtgctatt atccgtgacc
     8821 aagtggaaat tggtgacaat gctgttatca tgatgggagc tgttatcaat atcggtgctg
     8881 aaatcggtgc tggaaccatg attgacatgg gtgccatcct tggtggccgt gccatcgttg
     8941 gaaaaaatag ccacgttggt gcaggtgcag ttttggcagg tgtgattgag ccagctagtg
     9001 ctgaaccagt ccgtgtcgga gacaatgttc tcatcggggc taatgcagtg gttatcgaag
     9061 gagtccaaat cggtagtggt tcagttgtcg cagcaggagc tattgttacc caagatgtcc
     9121 cagaaaacgt ggtagtagca ggtgttccag ctcgtattat caaagaaatt gatgcccaaa
     9181 ctcaacaaaa aacagcgcta gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa
     9241 gaggcggaac cctttttcca gcctctttct gctatatcgg aggacagata gatgttagat
     9301 ttgattcaga ctagacgaga tttacaccag attccagaga ttggcttgga ggagttcaag
     9361 actcaggctt atttgctgga tgtgattgag aaattgacta cgggcaagga ttttgttcaa
     9421 attcgtactt ggcggacagg gattttggtc tacctgcagg gaagtcagcc ggagcgaacc
     9481 attggttggc ggacagatat tgatggcctg cctatcgtcg aacaaacagg tctacctttt
     9541 gcttctcaac accaaggtcg catgcatgcc tgtggccatg attttcatat gaccattgcc
     9601 ttaggctgtc ttgagcgcgc ccttgaggag caacccaaga ataatctgct ctttctattt
     9661 cagcctgctg aagaaaatga agctggtggt atgctcatgt atgaggacga tgcttttgga
     9721 gattggttgc cagatcaatt ttatggcctc catgtccgtc cagatttgaa agtcggccag
     9781 attgcgacta atactcatac actctttgca ggaacttgcg aggtgaagat ccgtttcaaa
     9841 ggcaaaggtg gccacgcagc ttttcctcat gaagccaatg acgccttggt ggcggctagt
     9901 tactttgtga cccaagtgca gtcagttgtt agccgcaatg tcaacccaat cgagggagca
     9961 gtggtgacct tcggcgtttt tcaagctgga accaccaaca atgtcatcac agacacagct
    10021 tttttacatg gaactattcg tgccttgaca caggacatga gtctcttggt gcaaaagagg
    10081 gtaaaaacag ttgcagaagg ggttgcagct gcctttgata tggaagtcga agtggaactc
    10141 aaacaaggtg gatacctacc tgttgagaac aatccagcct tggcgcgtga actgatggac
    10201 ttctttgacg aaaaagacgg aatcgagttg attgatatcg aacctgctat gacaggcgag
    10261 gactttggtt atctcctttc aaaggttgat ggcgtgatgt tttggctagg tatcgatagt
    10321 ccctacgctc ttcatcaccc tcaaatgagt cctaaggaag aagtcttagc tattggggtg
    10381 gctgcggtgt ctagtttcct gaaaaagaag gcagcagaat agagggcttg tctatgaaat
    10441 cggaattacg caagcaagtc ttgcatgaaa tgaaggctat atctcaagag caaaaacagg
    10501 ctatagacca agctttaacc gagcggcttt tacaccatcc cttctaccaa gaagccaagg
    10561 tcatcgcaac ctacctctct ttttctcatg agtttcaaac gcgggaactg attgagcagg
    10621 cgctgaagga cggcaagaag gttttaatac ccaaaactta tcccaagggg cgcatggagt
    10681 ttgtggccta tgatccgcaa cagttggtaa aaacttcctt tgccttactg gagccacagg
    10741 gagatgtgga agtggtggat gcatctcaga ttgatttgat tcatgttcct ggtctggctt
    10801 ttacgacgaa aggatatcgg ataggatacg gtggaggcta ttatgaccgc tatctggaac
    10861 atttttctgg tcgtactttg agtacgatat atccttgtca aattcaggac tttatacctg
    10921 aaaaccatga tattcctgtt caggaggtat taattgatga aggaaatctt tgatagacgt
    10981 taccctgtga cgagtttctt cctcttagtg acggccttgg tatttttact aatgttggtc
    11041 actgcaggcg gaaactttga cagggcagat acattatttc gatttggagc catgtatggg
    11101 ccagctattc gcctctttcc cgagcaggtt tggcgtctct tgtctgccat ttttgttcat
    11161 attgggtggg aacatttcat tgttaatatg ctttcacttt attatcttgg aaggcaggta
    11221 gaggagattt tcggttctaa gcagtttttc tttctctatc ttttatcagg aatgatgggc
    11281 aatctctttg tttttgtatt tagtcctaaa tccttagcag caggcgcctc tacctctctt
    11341 tatgggctat ttgccgcgat tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa
    11401 cagctagggc aatcctatct gacacttttt gtggttaaca ttattggaag tgttctgatt
    11461 ccaggaatca gcctagcagg ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt
    11521 atctttccag ttagaggaga aaaacggatg tataacacca gccagagatt aggagcggta
    11581 gtcttgttcg taggactcgc cattttgctt ttctacaagg gaatgggaat gtgacgaagt
    11641 tgaaagaaaa tttgtgtaat gaaaaaagat aaggcatttt ttgaacctta tctttttatt
    11701 ttattccttc tcagtcaatt cttttccaag ttggatgagg taattcttca aatcatcttt
    11761 gacttgtgga tgtttgaggg cgtagtcaat agatgttttc ataaagccaa acttatcccc
    11821 aacgtcgtaa cgagctcctg taaattcacg ggcaaaaaca cgctgtgttt tattaagagt
    11881 atcgattgca tcagtaagtt ggatttcatt tccagcacca ggagcttggt tttcgaggat
    11941 ttggaaaatt tcaggcgtga ggaggtagcg tccgataata gcaaggtcgc taggagcgtc
    12001 ctctggagct ggtttttcaa caaaggtttc aacactgtaa agaccatctt ttccttcgcc
    12061 ttgcggagca ataaccccgt aagcagatac ttcgtcatga gggactggca tgacagcgat
    12121 agtagacgcg tgggtacgct tgtagtcatc catgagttgt ttggtaagtg gaacagcctt
    12181 ttcgtctgtg atatccatca agtcatcacc aagcataacg acaaaaggtt catttccgac
    12241 gaaagccttg gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt ggcggataaa
    12301 atgcagacgc atgccagttg tttcatcaac tagcttcaaa agatctgttt tccctttttc
    12361 tttgaggtta tattccaatt cgaagtttga atcgaagtgg tcctcaatag aacgttttga
    12421 tttaccagtg acaactagaa tatcttcaat acctgatttg agagcctctt ccacgataaa
    12481 ctggatagtt ggtttgtcta cgattggcaa catttctttg gcaagggcct tggttgctgg
    12541 taaaaatcga gttcctagtc cagcagcagg gataactgcc tttctaactt ttgatgtcat
    12601 aaaaatcctt tctatagagg gttaagacca ctcattttct gctttaaatt cattgttcat
    12661 gatgtcataa atggcatctt tgatattggt tccgtgataa ataacttggt aaatagcctg
    12721 tgtaatgggc atatagactc caagttcttg ggctagttca taggctgctc gagtcgttga
    12781 aattccttcg attaccatgc ccatattagc ttctatatca gctagggatt ctcctcgtcc
    12841 gagagcatct ccagctctcc agttacgaga gtggatggaa gttcccgtta cgatcaaatc
    12901 tcccacacca gataagccgc tataggtcaa tggactggcc ccgagtgcta cccctaggcg
    12961 ggtgatttct gctaaacctc gagcgatgat ggctgcctta gcattatcac caaatccaag
    13021 accatgtaaa gctccagcac cgacagcaat aatattttta agagcaccag cagtttcaac
    13081 cccgataaca tccgtattgg tataaagtcg gaagtagtga ttactaaata gctcctgaac
    13141 gtattgagct gtttgtaaat ctttagaagc agcagttatt aaagttaggt cacgcacaat
    13201 ggtctcttct gcatgactag gccctgaaac aacgacgata tcactacgga gatgttcagg
    13261 aatttcttct tcaagaatgg ttgataatcg tttatggcta tcaggttcta atccctttga
    13321 tgcgtgcatg atgataacct tatggtccaa ggtttgtgca acttgctggg caacaagtcg
    13381 tgtcactttt gttgggacaa caaacaaaat cgcatccaca tttttcaatg tttctgctaa
    13441 gtcggtgtag gcaatgatat tttcgtctag aacgacatct ttaaagtagt gcttattagt
    13501 atggtgtgta ttaatttcat tgatttgctc gggaagattt ccccaaatac gtacctcgtg
    13561 tccattgtca tttaagactt gtgaaagggc ggttccccaa gaaccaggcc ccaagacggc
    13621 gacggtttgt ttttccatga tttcctcctt gatagatttc tttctcttat tctatcatat
    13681 tctaggggat tttgcacttg cattactggg gtatggtgga aaaatacaca aagaccgaga
    13741 tgaagggata aactcttagt ctttagttaa agtgagaaga aatctgatag atagtttgat
    13801 tcagtatatg cttataatag aggtaaacaa ctcaggaagt tcttgtaggt tgcgagagtt
    13861 tggcgaaaaa attaaaagat tacgtttggc taaaaaaatc agtcgttcag aattttgtgg
    13921 tgatgagtct gaattaagta tccgtcaatt aattagaatt gaaaatggag aatccagacc
    13981 aacactaaca aagttaaaat atattgctga acgtttggag gttgaagatt acaagttgat
    14041 gccaagttat atagagttgg ataaggaata cctagaattg aagtatttct tgatgaggac
    14101 tcctacatac gaagatgaaa ctatcgccca aaagaaagag agtgtttttg ataagatttt
    14161 tgaagagtat tatgataggc tacctgagga agaaagattt atcatcccaa attattcata
    14221 tctagcacta gcgaactaca cagttcaaaa attaccagaa aagctagttg aaatactgtc
    14281 cttctggtga ttttgcttaa tttctgatgt tcgagacatg attgaggaga tttgtcttga
    14341 ttttttccta aaaaagggca gactcctccc ttggtttgat gctcgatttt taaaataagg
    14401 tgacttattc tgttaggcag ttttcccctg ccctctagct ctatatggaa cagggagtat
    14461 cagatttatc tggcagattg tatcaaataa ggcttgaaac tgttttgaat aggcgtatag
    14521 acttgagaat ttgagaatat gtcgtctagc agtagagaca tattttccgg caatatgaag
    14581 gaagagacgt cgaaaacgct tgatagtcaa ggcctttact tcatcaccag ctagctgctt
    14641 taaaaagagg tagagattat aagccagaca gcccatcatc atacgtactt cattcttaat
    14701 catggtcgaa ctatctgtct tatccccaaa gaatcctgct ttcctttctt tgataaagtt
    14761 ttcagcattc cctcgttcac gatagaattg aaacagctcc tcactatcta cactgcttaa
    14821 attgttcaaa tgaacttttt tacaaccata aaaaagagca cttaatcgta ctcttctctt
    14881 ttaaggatta gttgaattaa ttcaaatcca ccagttctcc tgtttctagg tagactaggc
    14941 gttcacaaat gttagcaatg taatcagcga agcgttccag atgccctatg atataaaggt
    15001 attgagttcc attgggaatt gaggtttctt ggtctttcat aagtccaatg atttcctttg
    15061 ataaggcata ataatattgg tcaatctgtt catctttttg agcaatacta atagcttttg
    15121 aggcttggtg caaaggaaag gcaaccaata aatcggctag catgctgagg gataatttac
    15181 ccatttggtg taactgttct tcgtcagggg ctagttgatt ttcttttagt tgcaaaacag
    15241 ctttagcaat gcctgccata tggtctccca tacgttcaag gtctgaacaa gaagacatga
    15301 tgctaatcac aaatcgaagg tcagacactt gtggctgctg caaggccaac aaacgggcac
    15361 aggtcaattc gatagcgctt tgaccttggt tgatagcatg atccttattg ataattagct
    15421 ctgccatctc cttgtctttg gaggctaagg ccagtaaggt ttttgaagct gtttcaagga
    15481 caagttgccc tagtcctaaa aaggattgtt ctaattcatg caattctaag tcaaattgat
    15541 ttctcatagg tttttccttc cttatccgaa ccgtcctgaa atatagtctt ctgtgcgctg
    15601 atcttttgga ttggtaaaca cgtcaacggt gtctccaaat tcgcaaattt ctcctgttaa
    15661 gaaaaaagca gttttatctg aaatacgtga agcttgttgc atgttatggg taacaatgat
    15721 aatcgtataa tcctttttta gttgctgaat gaggtcttca atttttaaag tggagatagg
    15781 gtctaaggct gaagtcggct catccattaa cagaacatca ggttctactg ctaaagctcg
    15841 cgcaatgcaa aggcgttgct gctgaccgcc tgataaggac atggcactct ttttaagatt
    15901 atctttgact tcgtcccaaa tggctgcccc ttttaaagat ttttccacta aggcatctaa
    15961 ttgttttttg tctcgaatac catgtgtcct tgggccataa gccacgttat catagataga
    16021 catggcaaag ggattaggct gttgaaaaac catccctaca cgcttgcgta gctgattaag
    16081 gttgaatttg ctactataaa tatcttgctc atctaagagg acttggcctt caatatggca
    16141 agaaggaacc aaatcgttca tccgattaag ggtttttaga aaagttgatt taccacaacc
    16201 agatgggcct atcaaggcag taatctgtct ttctggtaat tgaatcgaaa tattttttaa
    16261 ggcttgaaaa tccccgtaaa ataagtctag gtgtctgact gaaaatgttc ccatactagg
    16321 aagctccttt cacaagtttt cgagataata agcttgatag agtatttatc attaaaacag
    16381 taataatcaa aatcacaccg gtagcatagg cttcattgac atgtagcccc tcacttgaca
    16441 gcatatacat atgcagggct agagaacgac ctgaagacat gagactactt ggcgtattgg
    16501 tagaggtacc taatgtatac atgagggcag ctgtctcacc aacgatacgg ccaatagcta
    16561 gtatcactcc agctaaaata cctggcatgg caactggtag aacaattcta aaaacagtcc
    16621 gtaacttacc tgccccaagt ccataacttg cttgacgcat gctatcacta acagataaaa
    16681 gggcttcttc tgttgagcga ataatgactg gcaacaccat gatgactgag gttaagattc
    16741 ctgataacag agagtattga aaacctaaga agactacaaa gaagagcatg ccaaacagac
    16801 caaaaacaat ggaaggaatc ccagacaagg tatctgaggc caatcgcatg attttaacac
    16861 aaagggaatc tttttttgta tattccacaa gataaaaacc agcaaaaatc cctatgggca
    16921 aggctaaaag aagagcacca aagaccagaa taacggtgga aataatcgct ggcataaggg
    16981 aaatgttctc agaagtataa gtccaagaaa agagggatag acttagatga ggtaaacctt
    17041 tgatgaggat aaaaccaatg attaaaaaga gagagccaaa ggttaaagct gaaaaacaat
    17101 aaacgagaag ttttagcagg tatttactca taagatgatt ttcctttcaa gtaggcaaag
    17161 taggcattaa tcaagagaat aaggaaaaag agaactgctg aggttgcaat aagggcttcc
    17221 ctatgctgac ctgatgcgta agccatttcc agaacaatat tggttgttaa ggttctggtt
    17281 cctgaaaaga gtccacttgg aataatcggc tggttgcctg ccaccaaaat aactgccatg
    17341 gtttcaccta ctgcgcgacc gatgcctaaa ataactgctg ataaaatacc agatctcgca
    17401 gctggcaaga tgacactaaa aatactccgt tcatgactag ctcctagagc caagctacca
    17461 gaataatacg ttttgggaac tgttcggata gcagattctg acaaactgat aatggttggc
    17521 aaaatcatta ttcctaatag taacgaagcg gttaggacac tcatgccatt tcctaaaaag
    17581 cttctaatcc aaggcaccaa taattgtagg ccgaaaaaac cataaacaat agatggaatg
    17641 gccgccatca agttgatagc tgattttaag aagccataga cgggctttgg acaataataa
    17701 accataaaca ccgatgtcaa gatgcctgtt ggcaccccaa tcacaatcgc tcctaaggta
    17761 attaataagg aaccaacgat cattggtaaa ataccatagc ttgccggaat gttcgttggc
    17821 gaccaatcac tgcctaataa aaaacgggca aagccgtagt tagccatgaa aggtaagcca
    17881 ttactaaaaa taaagaaaca gattagcaaa atagctacaa cagctactgt tgcactcatg
    17941 aaaaaaattg ccctaaaaac tgcttctttg aaggcttgtt ttatcacatc ttgtcctttc
    18001 tagtgaagaa agtaagggag atacgacacc tccctacttg ccttctttat cttattgtac
    18061 gatgaaacgt ctgcatctct ttagagattt atggagcaaa cattttattt aatcttgtcc
    18121 caggtggtta atttgccact aaaaacgtct gcaagttcag ccatactgac ttggcttgcc
    18181 ttattgtcat tattgaccac aatagcaata ccgtctaaag caatagcatc atgggtgaga
    18241 ctcttacctt cttcaggagt taattcccta gaaaccatac caatatcagc ggttttctcc
    18301 ttaacagcgg taatacctgc tgaagaccca ttagaggtaa tatcaatcgt aacttctgga
    18361 ttttcttttt tataagcttc tgctaatttt tccattaaag aagatactga agtggaacct
    18421 acaacagaca acttgcctga taagtgttgg cttgtatatt ctgtggtttc agttttagct
    18481 tcaataaatt tattatctgt gaccacttgt tgaccttgtt tggagtggat aaagctgata
    18541 aaatcttgac ctagcttgga aagattagaa gaccaaacaa tgttgaaggg acgttgaaga
    18601 gggtattcac catctaaaac tgtgtctcga ctagccttga caccatcaat ctctaaagcc
    18661 ttgacagatt tcgttaaaga tcccaaggag atgtagccga tagcattagc attcccttga
    18721 actgctgaga gaacaccttc tgtactattt tgaatcacag ctgttttggc agtgttgtca
    18781 atttttttat caccgtcttt tttgagaatc cctgtgattt ctgtgaaggc accccgtgtt
    18841 ccagagccat tttctcgtga aatcacctca atcgttcctg aagctgactg tttggaagca
    18901 gctgactgat tgccacaggc aacaagccca aatcctgata agccaatggc tgcaagagta
    18961 agcatttttt tgaatttcat aataatcacc tttatctcta tgtatttttc ttgtgtaggc
    19021 ttactacatt tatagtctaa caagtctttg taaaggttta tccctgattc atgtaaagat
    19081 tgtgtaaaga atcaaaaaaa gccacttttg aaaaatggct gctcctaaaa atagctttaa
    19141 aaattattag tcctgtgcga aagattggtt aggaagaaaa atcgtgaagc aactgcctct
    19201 gccaagctga ctcgtcaccg tgacttggcc acctaataat tgactgagtt ctttgacaat
    19261 ggcaaggcca agaccagtgc caccagtttg tctgcttcga cctttattaa ctcggtaaaa
    19321 acgttcaaaa atacgatcct gctctaattg actaatacca atccctgtat ctgatacaga
    19381 aatcttaatg ccttcgttca ccttttgggt cttgacctca atttttcccc cttgttcagt
    19441 gtaacggatg gcattggata aaagattgag taagatttgg gaaagtaatt gactatctga
    19501 tacgagggtg acatcatctg gcacctgcac ctttagctgt aaatccttct tcttgagctg
    19561 aggttgcaag ctttgagtca aatcctgtac aaattcagcc aaagaaaggg tcgtccattg
    19621 tataggcatt tgttgagcct tagataaggt aagaagatgc tcaacaatat gctcaagacg
    19681 caaactttct ttgtaaataa tgtctagaaa gtcatccttg agcgcttctt cttcagctga
    19741 catcccctta atggtttcag caaagccctt aattgaagta actggtgtcc tcaattcatg
    19801 ggaggcattt gagacaaagg ctaaatttaa cttttcataa gttctaatcg ttgttaaatc
    19861 atatagcaag acgagcacag cttccacaga ttgggtgggg ctaaaaacgg gaactgctgt
    19921 cacttctaaa atcaagtcac cctcatgaaa cccacttact tcttgtttta accttgtttt
    19981 ttgatcaaag gcttggtgaa ctaaattccg aatatccatc cgtttgaggt catcaagtga
    20041 acttatgtcg ccgtccacat cgggaaaata atgaggcaga gagcgactgg ataataacat
    20101 ctgaccttga gcggaaacta aaaacgtccc catggttagg tgcgacagaa gaacctccat
    20161 tgtttcggct aggtccttgt attgctgatc ctgttgggag actttggttt ttaggccaga
    20221 cacatactga gccaaagact ttaagtcttc ttgccctttt tctaaaaagt attcactact
    20281 ggtcaagaga ggttggtgca aggtctcaaa agcaacttcc catttccaaa ggcaaaagag
    20341 ccagtagcca ccttgtccca aagaaagggc tagaagaaag agaccgatgc ctttactgat
    20401 ccaagttaat gccatccctg caatcagaat gaggctaaca cttagattga ctagccaaaa
    20461 ttgaaggtag cgtttcatct ataactcctt gaacttataa ccataacccc gaatggttcg
    20521 aataaattga ggggctttag gattgtcttc aattttttcc ctcaacttac caatatgaac
    20581 gtccaccaaa cgtgtttcct gcccaaagtc atacccccag atacgttcca aaagacgctc
    20641 tctagtcagt gtcatgttgg gatgtttcat aagatagagc aagagttcaa attcttttgg
    20701 ggtcaaactc agtaacttat tcgccttgta gacttcatga cgctcagggt atactttcaa
    20761 ggtcccaaat agccaagaat cgtcagcgat attatctgaa tcatctcctt cttgttctcc
    20821 tttagttcgc ctgaggacag ccttgacacg cgccagcaat tctctagggc taaaaggctt
    20881 ggtcaggtag tcatcagccc ctaattccaa ggccaaaacc ttatcaaatt catcactttt
    20941 cgcagaaacc atcataattg gagttttgac gcctttggct ctcagccgct tacaaacttc
    21001 catgccatct aattgtggta acatgatatc aagcaagata aaatcaaagg gttctgtttc
    21061 tgccaaagct aaggccttcc gtccatttgt taccaattga gtagaaaagc cttccttact
    21121 taaatggtag tcaagcaatt tcagaatgtg ttcttcatca tccactaata agacttgttt
    21181 tgtcatctat tatctcctat tggtaacatt ataacacaat tatcagaaat cctaacattg
    21241 ctaaatcaga ttaaatttgc ttatcaagac tagtatctgg tcaaacgctc aatcatctcc
    21301 ttgtgctctg gataggtcgc cagtagatct accctttcaa ataattcaaa atcctcaaat
    21361 tcaaaaccag gagcaacaag acaagaaacc agagcataat ccttatcaac tgttgatccc
    21421 caaatagtgc ccttaggaac acagtagtga agttgttgcc ctttggatat gtccaggcct
    21481 aaagtgactg cttcgtagtg accatctgct gtaatcatgt gaacagtaag tggggatcct
    21541 gcatgaaaat accagatttc atctgctgtc aatcggtgaa aatgtgaagg attcgtttct
    21601 tctaataaga aataaatact ggtataaagc gcccttccct taccagcaag gtttatagtg
    21661 tctgaagctt tttttgtttg tctaaaatag ccaccttcaa catggggagc taactctaga
    21721 gttcttatca agtcttcttt atccatcggg gccaatgggt tgaagtaact cttgttcaaa
    21781 gtggttttac gatttcaaga actcctctca gttctgagga cacggtaatg attgatgcga
    21841 cggaagtaca aatcaatcgc cctaaaaaaa gaattagcga atgattctgg taaaaagaaa
    21901 tttcacgcta tgaaggctca agcgattgtc acaagtcaag ggagaattgt ttctattgcc
    21961 atgatatgaa gttgttcaaa atgagttgca gaaatatcgg acaagctggt aaaatcttgg
    22021 ctgacagtga ttatcaaggg ctcatgaaga tatatcctca agcacaaact ccacgtaaat
    22081 ccagcaaact caagccgcta acagctgaag ataaagccta taaccatgcg ctatctaagg
    22141 aaagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaata ttttcaacaa
    22201 cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct ggtattatca
    22261 atcatgaact aggattctag ttttgcagga agtctattat ttggttaggt gaattagtga
    22321 agtgtttagg caagtgtctc tggttacgac gtcatggcct ctaaatcgat tatatttagg
    22381 ggtcatgact agtgaagcag ttagctagtt cgcatataag cggctagcgt ctaacaatta
    22441 ggaactttag ttccaataac tttaagatta cgacgtttta ggacataaat cgatcatatt
    22501 tatgtcctaa aactagtgaa gcgcctagcc aaagtccgaa taggatttgg cgttagttac
    22561 ttagattgct ttgcaatcaa gtaactttgg cgatttacat cttctctggc gcttctactc
    22621 caagcaagcg aagggcttct ttgagaacga ctgcggttgc gtagctgagg gctagacggc
    22681 tgtcgcgttc tgggctttca tccaagatac gtgtatgtgc atagtatttg ttaaaggatt
    22741 gagccaggct aattgcaaat ttagcaatga tagaaggttc aaagttatct gccgcacggt
    22801 tgataatacg tgggaagtct tgaatgagtt taatgatttc ccagctttca gtatcattca
    22861 agctatagtt gccagctgtt tctggtttga aatcggcttt gcgtaagata gattggatac
    22921 gagcgtaggc atattgaacg taaggtccag tttcaccctc gaaggatacc atagcttcta
    22981 ggtcgaagtc gtatccattt gtacggtcag ttttgaggtc atagaattta atggctccaa
    23041 ccccaacagc atgtgctact tggtctttgt tttctagttc aggattttta gcctcgattt
    23101 ggaccttggc acggctaaca gcctctgcaa cagtaggctc tagcaagatg acattccctt
    23161 tacgagtaga gagcttcttc ccttcttttg taaccagacc aaaaggaacg tgggtaatgt
    23221 cgtcactcca atcgtagccc atctcttgca agacagcttt gagttgttta aagtgggcag
    23281 attgctcttg accaacgacg tagatagatt tagcaaattg gtattcattt ttacggtaga
    23341 gggctgcagc caagtcacgt gtgatataga gagttgcacc atcagacttc ttgatgaggg
    23401 ctggatgttc aattccatat ttctcaagat tcacaacttg ggcaccttct gattcaagaa
    23461 gtagtccttt ttcagaaaga atgtctacaa ctgcatccat cttatcattg tagaaggctt
    23521 ctccgttata gctgtcaaat tcaaccttca attcattgta aaggcggtta aattccacta
    23581 aactttcatc gcggaaccat tgccaaagag cgagagcttc ctcatctcca ttttcaagtt
    23641 tacggaacca ttcgcgcgct tcttcatcca agctagggtc attttcagct tcagcgttga
    23701 tgcggacata gagtttaagg agttcatcga ttggatgagc ttttacagct tcttcgtcgc
    23761 cccatttttt gtaggcaaca atcaacatcc caaattgttt accccagtct cccaaatggt
    23821 tgaccttgac cgtttgataa ccgatttttt ggaaaatatg tgacaagcta tctccgataa
    23881 cagttgaacg caggtggcca atagaaaatg gtttagcgat attcggacta gacatgtcga
    23941 taacaacatt ttcttgtttg ccaatatttt ggtcagcata gtgttctttt tcagtggtaa
    24001 cagcttgcaa tacttgagca gaaatggcag atttatcaag gaaaaagtta acgtaaggtc
    24061 ctgttgcgac aactttttca aaggcttggc tgttcatttt ttcagccagt tcagccgcaa
    24121 tcatttgtgg tgctttacgt tcgactttgg caagagaaaa agcagggaaa gcaatgtctc
    24181 ccatttctga gtttttaggg gtttccagta actttaaaat agcctcttgg tccaggctat
    24241 caatgatgct agataattcg ctagcaatca attcttttgt attcattaag agctcctttt
    24301 tggacttttc tactatttta tcacaatttt aaagaaagaa gaaaaaattt ttgaaatctc
    24361 ctgttttttt ggtataatat ggttataaat atagttataa atatgcacgc aagaggattt
    24421 tatgagaaaa agagatcgtc atcagttaat aaaaaaaatg attactgagg agaaattaag
    24481 tacacaaaaa gaaattcaag atcggttgga ggcgcacaat gtttgtgtga cgcagacaac
    24541 cttgtctcgt gatttgcgcg aaatcggctt gaccaaggtc aagaaaaatg atatggtgta
    24601 ttatgtacta gtaaatgaga cagaaaagat tgatttggtg gaatttttgt ctcatcattt
    24661 agaaggtgtt gcaagagcag agtttacctt ggtgcttcat accaaattgg gagaagcctc
    24721 tgttttggca aatattgtag atgtaaacaa ggatgaatgg attttaggaa cagttgctgg
    24781 tgccaatacc ttattggtta tttgtcgaga tcagcacgtt gccaaactca tggaagatcg
    24841 tttgctagat ttgatgaaag ataagtaagg tcttgggagt tgctctcaag acttattttt
    24901 gaaaaggaga gacagaaaat ggcgatagaa aagctatcac ccggcatgca acagtatgtg
    24961 gatattaaaa agcaatatcc agatgctttt ttgctctttc ggatgggtga tttttatgaa
    25021 ttattttatg aggatgcggt caatgctgcg cagattctgg aaatttcctt aacgagtcgc
    25081 aacaagaatg ccgacaatcc gatccctatg gcgggtgttc cctatcattc tgcccaacag
    25141 tatatcgatg tcttgattga gcagggttat aaggtggcta tcgcagagca gatggaagat
    25201 cctaaacaag cagttggggt tgttaaacga gaggttgttc aggtcattac gccagggaca
    25261 gtggtcgata gcagtaagcc ggacagtcag aataattttt tggtttccat agaccgcgaa
    25321 ggcaatcaat ttggcctagc ttatatggat ttggtgacgg gtgactttta tgtgacaggt
    25381 cttttggatt tcacgctggt ttgtggggaa atccgtaacc tcaaggctcg agaagtggtg
    25441 ttgggttatg acttgtctga ggaagaagaa caaatcctca gccgccagat gaatctggta
    25501 ctctcttatg aaaaagaaag ctttgaagac cttcatttat tggatttgcg attggcaacg
    25561 gtggagcaaa cggcatctag taagctgctc cagtatgttc atcggactca gatgagggaa
    25621 ttgaaccacc tcaaacctgt tatccgctac gaaattaagg atttcttgca gatggattat
    25681 gcgaccaagg ctagtctgga tttggttgag aatgctcgct caggtaagaa acaaggcagt
    25741 cttttctggc ttttggatga aaccaaaacg gctatgggga tgcgtctctt gcgttcttgg
    25801 attcatcgcc ccttgattga taaggaacga atcgtccaac gtcaagaagt agtgcaggtc
    25861 tttctcgacc atttctttga gcgtagtgac ttgacagaca gtctcaaggg tgtttatgac
    25921 attgagcgct tggctagtcg tgtttctttt ggtaaaacca atccaaagga tctcttgcag
    25981 ttggcgacta ccttgtctag tgtgccacgg attcgtgcga ttttagaagg gatggagcaa
    26041 cctactctag cctatctcat cgcacaactg gatgcaatcc ctgagttgga gagtttgatt
    26101 agcgcagcga ttgctcctga agctcctcat gtgattacag atgggggaat tatccggact
    26161 ggatttgatg agactttaga caagtatcgt tgcgttctca gagaagggac tagctggatt
    26221 gctgagattg aggctaagga gcgagaaaac tctggtatca gcacgctcaa gattgactac
    26281 aataaaaagg atggctacta ttttcatgtg accaattcgc aactgggaaa tgtgccagcc
    26341 cactttttcc gcaaggcgac gctgaaaaac tcagaacgct ttggaaccga agaattagcc
    26401 cgtatcgagg gagatatgct tgaggcgcgt gagaagtcag ccaacctcga atacgaaata
    26461 tttatgcgca ttcgtgaaga ggtcggcaag tacatccagc gtttacaagc tctagcccaa
    26521 ggaattgcga cggttgatgt cttacagagt ctggcggttg tggctgaaac ccagcatttg
    26581 attcgacctg agtttggtga cgattcacaa attgatatcc ggaaagggcg ccatgctgtc
    26641 gttgaaaagg ttatgggggc tcagacctat attccaaata cgattcagat ggcagaagat
    26701 accagtattc aactggttac agggccaaac atgagtggga agtctaccta tatgcgtcag
    26761 ttagccatga cggcggttat ggcccagctg ggttcctatg ttcctgctga aagcgcccat
    26821 ttaccgattt ttgatgcgat ttttacccgt atcggagcag cagatgactt ggtttcgggt
    26881 cagtcaacct ttatggtgga gatgatggag gccaataatg ccatttcgca tgcgaccaag
    26941 aactctctca ttctctttga tgaattggga cgtggaactg caacttatga cgggatggct
    27001 cttgctcagt ccatcatcga atatatccat gagcacatcg gagctaagac cctctttgcg
    27061 acccactacc atgagttgac tagtctggag tctagtttac aacacttggt caatgtccac
    27121 gtggcaactt tggagcagga tgggcaggtc accttccttc acaagattga accgggacca
    27181 gctgataaat cctacggtat ccatgttgcc aagattgctg gcttgccagc agacctttta
    27241 gcaagggcgg ataagatttt gactcagcta gagaatcaag gaacagagag tcctcctccc
    27301 atgagacaaa ctagtgctgt cactgaacag atttcactct ttgatagggc agaagagcat
    27361 cctatcctag cagaattagc taaactggat gtgtataata tgacacctat gcaggttatg
    27421 aatgtcttag tagagttaaa acagaaacta taaaaccaag actcactagt taatctagct
    27481 gtatcaagga gacttctttg acaattctcc acttttttgc tagaataaca tcacagaaac
    27541 agaatgaaaa ggagctgacg cattgtcgct cccttttgtc tattttttaa ggagaaagta
    27601 tgctgattca gaaaataaaa acctacaagt ggcaggccct ggcttcgctc ctgatgacag
    27661 gcttgatggt tgctagttca cttctgcaac cgcgttatct gcaggaagtc ttaggcgccc
    27721 tccttgctgg gaaatatgaa gctatttata gtatcggggc ttggttgatt ggtgtggccg
    27781 tagtcggtct agttgctggt ggactcaatg ttgtcctcgc agcctatatt gcccaaggag
    27841 tttcatccga ccttcgggag gatgccttcc gtaaaattca aaccttttct tatgctgata
    27901 ttgaacaatt taatgcggga aatctagtcg ttcgaatgac aaatgatatc aaccagattc
    27961 agaacgttgt catgatgacc ttccagattc ttttcagact tcccctcttg ttcatcggtt
    28021 cgtttatcct agcggttcaa accttacctt ctctgtggtg ggtgattgtt ctcatggtag
    28081 tcttgatttt tggtttgact gctgtcatga tgggaatgat ggggcctcgt tttgccaagt
    28141 ttcaaaccct tcttgagcgc atcaatgcca ttgccaagga aaatttacgt ggcgttcgtg
    28201 tggtcaagtc ctttgtccaa gaaaaagagc aatttgctaa gtttacagag gtctcagacg
    28261 agcttcttgg tcaaaacctt tacattggtt atgccttttc agtagtggaa ccctttatga
    28321 tgttggttgg ttacggggcg gtcttcctct ctatttggct ggtcgcggga atggttcagt
    28381 cggatccgtc tgttgttggt tccatcgctt cttttgttaa ttacctaagc cagattatct
    28441 ttaccattgt tatggttgga tttttgggaa attctgtcag ccgtgccatg atttccatgc
    28501 gtcgtattcg agaaattctt gacgcagagc cagctatgac cttcaaggat atcccagatg
    28561 aagagttggt tggaagcctt agctttgaaa atgtgacctt tacctatcca atggacaagg
    28621 aaccgatgct gaaagatgtg agctttacta ttgaacctgg tcaaatggtt ggtgtagttg
    28681 gagcgactgg tgcaggaaag tcaaccttgg ctcaattgat tccacgtctc tttgatccac
    28741 aggaaggggc tatcaaaatc ggaggtaagg atattcgaga agtgagtgaa ggaaccctgc
    28801 gtaaaacagt ttccatcgtt ctccaacgtg ccattctttt tagtggaacg attgcagata
    28861 acttgagaca ggggaaggga aatgctactc tatttgaaat ggagcgcgca gccaatattg
    28921 cccaggctag tgaattcatt catcgtatgg agaaaacctt tgaaagtcca gttgaagaac
    28981 ggggaaccaa tttctctggt ggacaaaaac aaaggatgtc gattgcgcgt gggattgtca
    29041 gcaatccacg tattctgatt tttgatgatt cgacctcagc cttggatgcc aaatcagagc
    29101 gcttggtgca agaagctttg aataaggact tgaaggggac gacaaccatt attattgctc
    29161 aaaaaattag ctcggttgtc catgcagaca agatcttggt tctaaatcaa ggacgattga
    29221 ttggtcaagg cacgcatgca gacttggttg ccaacaatgc cgtttaccgt gaaatctatg
    29281 aaacacagaa atgaaagaca aactataaga aaagtcaata gttttatcta aactatttct
    29341 tatttcaatt tgatgatttg gcgatgattt tagagcacgg caaaaagcta ttgaaaaagt
    29401 ccattttttc aaaggtaatc ctgtgttaat ttcagaaatt acatcacttt ttgttcgtca
    29461 aatggcagct cttttttagg atataaaaca gggttcggat aagttttttt gcaaggtgga
    29521 tgatggctac attgtaatgt tttccttgtt ctaacttagt cttaagatag gccttaaaag
    29581 caggtgaaaa gcgagggcat gctttggcag cttgtatgag tacctaccgc agatgagggg
    29641 aaccccgttt gaccattctt cctgctaaat caatctgacc tgactgataa atagaagaat
    29701 ccagtccagc gaaagcttgt aattgagcag gattatcaaa ggcatgaata tttcgaatct
    29761 cggctaaaat gaccgcccct aaacgattct caatcccagt aaccgtcgtg atgaccgagt
    29821 tgaactcagc catcaagtca ttgacacatt ttttcgcctt gtcaatgagc ctcttgtaat
    29881 gtttgatgtt ttcattacaa gagataaaac gtttatgcgt tatcaaactc attaccaatt
    29941 gaaacaaaaa gctgtggtta gatcctttcg gaaattgtca agcgattgga ggaaatgaac
    30001 taatccacag cggcttattc caagtatacc acttgggctt tggcagtagc taactgcgct
    30061 aaatataata taaggaggag taaaatgaag acagttcaat ttttttggca ttattttaag
    30121 gtctacaagt tctcatttgt agttgtcatc ctgatgattg ttctggcgac ttttgcccaa
    30181 gccctctttc cagtcttttc tggacaagcg gtgacgcagc tagccaattt agttcaagct
    30241 tatcaaaatg gcaatccaga acttgtatgg caaagcctat caggaatcat ggtcaatctt
    30301 ggcctgctgg ttttggttct atttatctct agtgtaatat acatgtgtct catgacgcgc
    30361 gtgattgcag aatcgaccaa cgagatgcgc aaaggcctct ttggtaagct tgctcagttg
    30421 acggtttctt tctttgaccg tcgacaagat ggcgatatcc tgtctcattt taccagtgat
    30481 ttggataata tcctccaagc ctttaacgaa agcttgattc aggtcatgag caatattgtt
    30541 ttatacattg gtctgattct tgtcatgttt tcgagaaatg tgacgctggc tctcatcacc
    30601 attgccagca ccccattggc tttccttatg ctgattttca tcgtgaaaat ggcacgtaaa
    30661 tacaccaacc tccagcagaa agaggtaggg aagctcaacg cctatatgga tgagagcatc
    30721 tcaggccaaa aagccgtgat tgtgcaagga attcaagagg atatgatggc aggatttctt
    30781 gaacaaaatg agcgcgtgcg caaggcaacc tttaaaggaa gaatgttctc aggaattctt
    30841 ttccctgtca tgaatgggat gagcctgatt aatacagcca tcgtcatctt tgctggttcg
    30901 gctgtacttt tgaatgataa gtctattgaa acaagtacag ccctaggttt gattgttatg
    30961 tttgcacaat tttcacagca gtactaccag cctattatcc aagttgcagc gagttgggga
    31021 agccttcagt tggcctttac tggagctgaa cgaattcagg aaatgtttga tgcagaggag
    31081 gaaatccgac ctgaaaaggc tccaaccttc actaagttgc aagaaagtgt tgaaatcagt
    31141 catatcgatt tttcatactt gcctgataaa cctattttga aagatgtcag catttctgcc
    31201 cctaaaggcc agatgacagc agttgttggg cctacaggtt caggaaaaac gactattatg
    31261 aacctcatca atcgctttta tgatgttgat gctggtggta tttattttga tggtaaagac
    31321 attcgtggct atgacttaga tagtcttaga agcaaggtgg gaattgtatt gcaagattcg
    31381 gtcttgttta gcggaacgat tcgagacaat atccgatttg gtgtgccaga tgctaatcag
    31441 gaaatggttg aggtagcagc aaaagcaacc cacattcacg actatatcga aagtttgcct
    31501 gataagtacg atactcttat tgatgatgac cagagcatct tttcaacagg gcagaagcaa
    31561 ttgatttcaa tcgctcgaac cctgatgaca gatccagaag ttctcattct cgatgaagca
    31621 acttcaaacg tagatacggt gacggaaagc aagattcagc atgccatgga ggtggttgta
    31681 gcaggtagaa ctagtttcgt cattgcccac cgcttgaaaa ccattctcaa tgcagatcag
    31741 attattgtcc ttaaagatgg agaagtcatt gaacgtggta accaccatga acttttgaag
    31801 ctaggtggct tttattcaga actctatcac aatcaatttg ttttcgaata agaaagaagt
    31861 tgtcctatgt gggcagcttt ttcttgtcca taaaaaatgt ttatcacagc cttaaaaaaa
    31921 acatattaga cgaaagtcat tttgagtgat atgataggac tatcgttagt attcgaaagg
    31981 agaggcatca tggctagaac ggttgtagga gttgctgcaa atctatgtcc cgtagacgca
    32041 gaaggcaaaa tcattcattc atctgtatct tgtagattcg cagagatcat tcgtcaagtc
    32101 ggtggtctcc ctttagtcat tcctgttggt gatgagtcag ttgtacgtga ttatgtggaa
    32161 atgattgaca aactcatttt gacaggaggc caaaatgttc atcctcagtt ttatggagag
    32221 aaaaagaccg tcgaaagcga tgattacaat ctggtccgtg acgaatttga attggcactc
    32281 ttgaaggaag cgcttcgtca gaataaacca attatggcaa tctgtcgcgg tgtccaactt
    32341 gtcaatgttg cctttggtgg aaccctcaat caagaaatcg aaggtcactg gcaaggacta
    32401 cctttcggga catctcactc tattgagaca gtagaaggaa gcgtggtggc taagctattt
    32461 gggaaagaaa gtcaggtcaa ctcagtccat cgtcaaagca ttaaagattt ggcacctaat
    32521 ttccgtgtaa ctgctattga ttcaagagac caaactattg aagcgattga gtctatcgac
    32581 gagcaccgca ttatcggttt acagtggcat ccagagtttc tggttaatga agaagatggc
    32641 aatttagaat tatttgagta tttattgaat gaactgtaac gattggaaca tctggtcgtt
    32701 ctttctttta ttttttcaaa atttttagaa tgtggcattt tacgcaaacg tttgaattct
    32761 gataaaaatt ggagaaattc gacaaaaaaa cttgaaaaaa acgaaggtaa gcgttatgat
    32821 agaaaagaag aaatattgga ggaagaacat gtcacatatt aaatttgatt attcaaaagt
    32881 tttagacaaa tttgttgcac cacatgaagt ggaatacatg caatcacaag taacagcagc
    32941 agatgaattg atccgtaaag gaactggtgc tggtagcgac ttcttgggat ggttggacct
    33001 tcctgaaaaa tacgaccgcg aagaatttga ccgcatcttg aaagctgctg agcaaatcaa
    33061 gtcagacagc gatgttttgg ttgtgatcgg tattggtgga tcttaccttg gtgcaaaagc
    33121 agcaatcgac ttcttgaatc accattttgc taacttgcaa acaaaagaag aacgcaaagc
    33181 tccacaaatc ctttacgcag gaaactcaat ctcatctact taccttgctg acttggtaga
    33241 gtatgttgca gacaaagact tctcagtaaa cgtaatttct aaatcaggta caacaactga
    33301 accagcgatt gctttccgtg tctttaaaga actcttggtt aagaaatacg gtcaagaaga
    33361 agctaacaaa cgtatctatg caacaactga ccgccaaaag ggtgctgtta aggttgaagc
    33421 agacgctaac ggttggggaa catttgttgt tccagatgat atcggtggac gcttctcagt
    33481 attgacagcc gttggtttgc ttccaatcgc agcatcagga gctgacatca aagctcttat
    33541 ggaaggtgcg aatgcagctc gcaaagacta cacttcagac aaaatctctg aaaacgaagc
    33601 ttaccaatac gcagtcgttc gtaacatcct ttatcgtaaa ggctatgcaa ctgagatctt
    33661 ggtaaactat gagccatcac ttcaatactt ctcagaatgg tggaaacaat tggctggtga
    33721 atcagaagga aaagaccaaa aaggtatcta cccaacttca gccaacttct caactgactt
    33781 gcactcactt ggtcaattta tccaagaagg aactcgtatc atgtttgaaa cagttgtccg
    33841 tgttgacaaa cctcgtaaaa acgtgcttat tcctactttg gaagaagacc ttgacggact
    33901 tggttacctt caaggaaaag acgttgactt tgtaaacaaa aaagcaactg acggtgttct
    33961 tcttgcccac acagatggtg atgtaccaaa catgtatgtg actcttccag agcaagacgc
    34021 tttcactctt ggttacacta tctacttctt cgaattggca attgcccttt caggttactt
    34081 gaatgctatc aacccatttg accaaccagg tgttgaagct tataaacgta acatgtttgc
    34141 ccttcttgga aaaccaggat ttgaagaatt gagcaaagaa cttaacgcac gtctataata
    34201 gaagaaaaga gtggtttgcc cactcttttt actctcttta tccatagaaa ttggactcag
    34261 ccaagacttg tgatataata tagaaagcaa aaaggcagac gcctagataa taggagaaac
    34321 tatgtcaaaa gatatccgcg tacgttacgc accaagtcca acaggactac tacacatcgg
    34381 aaatgcccgt acagcattgt ttaactactt gtatgcgcgc catcatggtg gaacatttct
    34441 catccgtatc gaagatactg accgtaaacg ccatgtcgag gatggtgaac gttcacaact
    34501 tgaaaacctt cgctggttag gcatggattg ggatgaaagt ccagaatcac atgagaatta
    34561 tcgccagtct gagcgtttgg acttgtatca aaaatacatt gaccaactat tagctgaagg
    34621 aaaagcctat aaatcttacg ttacagaaga agagttggca gctgaacgtg aacgtcaaga
    34681 agtagctggc gaaacaccac gctacatcaa tgaatacctt ggtatgagtg aagaagaaaa
    34741 agcggcttat atcgcagaac gtgaagcagc tggtatcata ccaacagttc gtttggctgt
    34801 caatgagtca ggtatctaca agtggcatga tatggtcaaa ggtgatatcg aatttgaagg
    34861 tggcaatatc ggcggtgact gggttatcca aaagaaagac ggttacccaa cttacaactt
    34921 tgccgttgtt atcgatgacc acgatatgca aatctctcat gttatccgtg gagatgacca
    34981 tattgctaat acaccaaaac agcttatggt ctatgaagct cttggttggg aagctccaga
    35041 gtttggtcac atgaccttga ttatcaactc tgagactggt aagaagttat ctaaacgtga
    35101 tactaataca cttcaattta tcgaagatta ccgaaagaaa ggttaccttc cagaagcagt
    35161 ctttaacttt attgctcttc ttggttggaa cccaggtggt gaagatgaga ttttctctcg
    35221 tgaagaactc attaaacttt ttgatgaaaa ccgcctcagc aagtcaccag cagcctttga
    35281 tcagaaaaaa ttagactgga tgagcaatga ttatatcaag aatgcagacc ttgaaaccat
    35341 ctttgaaatg gcaaaaccat tcttagagga agcaggccgt ttgactgaca aggctgaaaa
    35401 attagttgag ctctataaac cacaaatgaa atcagtagat gagattatcc cattgacaga
    35461 tcttttcttc tcagatttcc cagaattgac agaagcagag cgcgaagtca tgacgggtga
    35521 aacagttcca acagttcttg aagcattcaa agcaaaactt gaagcgatga cagatgatga
    35581 atttgtgaca gaaaatatct tcccacaaat taaagcagtc caaaaagaaa caggtattaa
    35641 agggaaaaat cttttcatgc ctattcgtat cgcagtttca ggcgaaatgc atgggccaga
    35701 attaccagat acaattttct tgcttggacg tgaaaaatca attcagcata tcgaaaacat
    35761 tctaaaagaa atctctaaat aaagaggata caataatgga catctgggaa aagatgtacg
    35821 aagaagcaca gaaactatac aatccacatg aagtatcaga ctttgtttat gccaatcatg
    35881 ttgtagctgc agtagaagca ggagatggac aaatatttac aggattctgt atggagggaa
    35941 cctgtggtgt tttccatctc tgcgcagaac gggcgaccct cttcaatatg taccaatttt
    36001 caggacaaac taaggttaag aaagtattag cctttcgaga caaaccacct tatggtggaa
    36061 gttcagccat gccttgcggt gcttgtagag aattcctttt agagcttaat gctgaaaata
    36121 aagatgcaga attcatgatg gactataata taagaaaaac agttaaagtc gcagaactaa
    36181 tcccttattg gtggggagaa gaacgtgctt ctaagtttaa tgagtgatag aagagtcagt
    36241 ataattctgg ctctttttac tataagttga aaaaataaaa aaaattagaa aaagtagttg
    36301 acaaaatttg aaaagactgt ataatagtaa gagttgaaaa tagcaactca ggtccgttgg
    36361 tcaaggggtt aagacaccgc cttttcacgg cggtaacacg ggttcgaatc ccgtacggac
    36421 tatggtatgt tgcgtcagga gcacttgatg aaaaaaagtt t
//
LOCUS       DAVLHB010000018        35670 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLHB010000018 DAVLHB010000000
VERSION     DAVLHB010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.018"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(127..1551)
                     /locus_tag="VXE36_001004"
     CDS             complement(127..1551)
                     /locus_tag="VXE36_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0779325.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     SLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2095..4374)
                     /gene="pulA"
                     /locus_tag="VXE36_001005"
     CDS             complement(2095..4374)
                     /gene="pulA"
                     /locus_tag="VXE36_001005"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0779326.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEENLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4486..6444)
                     /gene="ligA"
                     /locus_tag="VXE36_001006"
     CDS             complement(4486..6444)
                     /gene="ligA"
                     /locus_tag="VXE36_001006"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0779327.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6537..7715)
                     /locus_tag="VXE36_001007"
     CDS             complement(6537..7715)
                     /locus_tag="VXE36_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0779328.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAEVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7795..8658)
                     /locus_tag="VXE36_001008"
     CDS             complement(7795..8658)
                     /locus_tag="VXE36_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0779329.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8661..10562)
                     /locus_tag="VXE36_001009"
     CDS             complement(8661..10562)
                     /locus_tag="VXE36_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0779330.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKFSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(10988..11263)
                     /locus_tag="VXE36_001010"
     CDS             complement(10988..11263)
                     /locus_tag="VXE36_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0779331.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(11369..12208)
                     /locus_tag="VXE36_001011"
     CDS             complement(11369..12208)
                     /locus_tag="VXE36_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0779332.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            12350..13198
                     /locus_tag="VXE36_001012"
     CDS             12350..13198
                     /locus_tag="VXE36_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0779333.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(13291..14208)
                     /locus_tag="VXE36_001013"
     CDS             complement(13291..14208)
                     /locus_tag="VXE36_001013"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0779334.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            14646..14851
                     /locus_tag="VXE36_001014"
                     /pseudo
     CDS             14646..14851
                     /locus_tag="VXE36_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(15162..15455)
                     /gene="rpmA"
                     /locus_tag="VXE36_001015"
     CDS             complement(15162..15455)
                     /gene="rpmA"
                     /locus_tag="VXE36_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0779335.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(15472..15816)
                     /locus_tag="VXE36_001016"
     CDS             complement(15472..15816)
                     /locus_tag="VXE36_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0779336.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(15832..16146)
                     /gene="rplU"
                     /locus_tag="VXE36_001017"
     CDS             complement(15832..16146)
                     /gene="rplU"
                     /locus_tag="VXE36_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0779337.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(16182..16269)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(16334..17032)
                     /locus_tag="VXE36_001018"
     CDS             complement(16334..17032)
                     /locus_tag="VXE36_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0779338.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            17434..17733
                     /locus_tag="VXE36_001019"
     CDS             17434..17733
                     /locus_tag="VXE36_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0779339.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(18075..19049)
                     /gene="pta"
                     /locus_tag="VXE36_001020"
     CDS             complement(18075..19049)
                     /gene="pta"
                     /locus_tag="VXE36_001020"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0779340.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(19093..19989)
                     /locus_tag="VXE36_001021"
     CDS             complement(19093..19989)
                     /locus_tag="VXE36_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0779341.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(19986..20804)
                     /locus_tag="VXE36_001022"
     CDS             complement(19986..20804)
                     /locus_tag="VXE36_001022"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0779342.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(20788..21459)
                     /locus_tag="VXE36_001023"
     CDS             complement(20788..21459)
                     /locus_tag="VXE36_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0779343.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            21587..22156
                     /locus_tag="VXE36_001024"
     CDS             21587..22156
                     /locus_tag="VXE36_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0779344.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQLTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            22269..23228
                     /locus_tag="VXE36_001025"
     CDS             22269..23228
                     /locus_tag="VXE36_001025"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0779345.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            23238..24353
                     /locus_tag="VXE36_001026"
     CDS             23238..24353
                     /locus_tag="VXE36_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0779346.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEANNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            24358..24705
                     /locus_tag="VXE36_001027"
     CDS             24358..24705
                     /locus_tag="VXE36_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0779347.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            24713..24928
                     /locus_tag="VXE36_001028"
     CDS             24713..24928
                     /locus_tag="VXE36_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0779348.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            25011..25652
                     /locus_tag="VXE36_001029"
     CDS             25011..25652
                     /locus_tag="VXE36_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0779349.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            25670..26359
                     /locus_tag="VXE36_001030"
     CDS             25670..26359
                     /locus_tag="VXE36_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0779350.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26356..27036)
                     /gene="radC"
                     /locus_tag="VXE36_001031"
     CDS             complement(26356..27036)
                     /gene="radC"
                     /locus_tag="VXE36_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0779351.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(27079..29370)
                     /gene="pcrA"
                     /locus_tag="VXE36_001032"
     CDS             complement(27079..29370)
                     /gene="pcrA"
                     /locus_tag="VXE36_001032"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0779352.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(29562..30366)
                     /locus_tag="VXE36_001033"
     CDS             complement(join(29562..29996,29998..30366))
                     /locus_tag="VXE36_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0779353.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMSTLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     SHDMKLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(30747..31607)
                     /locus_tag="VXE36_001034"
     CDS             complement(30747..31607)
                     /locus_tag="VXE36_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0779354.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(31623..32900)
                     /locus_tag="VXE36_001035"
     CDS             complement(31623..32900)
                     /locus_tag="VXE36_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0779355.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(32893..33444)
                     /locus_tag="VXE36_001036"
     CDS             complement(32893..33444)
                     /locus_tag="VXE36_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779356.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(33460..34719)
                     /locus_tag="VXE36_001037"
     CDS             complement(33460..34719)
                     /locus_tag="VXE36_001037"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0779357.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASIKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT        10850 a         7696 c         6351 g        10773 t
ORIGIN      
        1 gaagtagagc tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt
       61 tctataatta ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt
      121 tacacgttat ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata
      181 tttaattcct tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg
      241 accacgctgg gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc
      301 aaaggctttt ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt
      361 ggcaaaggca atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa
      421 tggctcttcc catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag
      481 aagattgccc tcacgtttga ttggtgtaag agcctgagct tctttttctt gtgcatcctc
      541 aatcaagctc caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt
      601 gtcaaatgga tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt
      661 atctgctaca ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta
      721 gctaaaggct cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac
      781 aagagctgca tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc
      841 aatacgttct ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc
      901 aatgatataa tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg
      961 aatccctgct tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg
     1021 tggcttaaac atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa
     1081 attaactgga taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac
     1141 aacagccagt ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt
     1201 gatacggaga ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc
     1261 aattgctgct ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt
     1321 atcgcgttct aaaatagctg ctgttttatg taaataagcc gcacgttcaa ctgctgataa
     1381 agctcgccat gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg
     1441 agtcatggct ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc
     1501 ttgttcagat gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc
     1561 ctcctgaaaa tgattaagat atattttacc aaattttcag aaaataacaa ccctttttgc
     1621 aaaatttttg agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa
     1681 aaaatccact acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa
     1741 tgagtatcat ctatagtaaa ataaaaaaac tgaacaattt ggttggggac agccaaacca
     1801 atttctcaca atgttttaga aacaagggtg tgctattcca atttcagcct actataactg
     1861 tcatagattg ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca
     1921 aatgttcaaa aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat
     1981 acaagtgagc tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta
     2041 ccaatactca taactgggaa tttttctgtc taaaaatagc gagatagatg gtatttataa
     2101 aacactcaag acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt
     2161 ggttaccaac atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt
     2221 cacaactacc aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc
     2281 aatcgcagaa tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc
     2341 accagttttt gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc
     2401 attaatcaag ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc
     2461 acgctctcta tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg
     2521 accaaattct tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt
     2581 ggcagtttcg accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa
     2641 taaatcgtga agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg
     2701 tgtatagctt cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc
     2761 agcaccactg acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc
     2821 gcgctgattg tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc
     2881 cttatcataa ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt
     2941 ggagtcgatt tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc
     3001 catcaagtca aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc
     3061 aatcatatac ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc
     3121 attctggaag gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa
     3181 tggtgcatca acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc
     3241 cgcatcgtga taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc
     3301 tggattagtt gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt
     3361 gtaggttaca tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg
     3421 aacataattg tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt
     3481 aactgttcca gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga
     3541 tgtaggtgat ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt
     3601 ttccaagcgc caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc
     3661 tacatggctc agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc
     3721 acgtgtcagt gtttggtgat gagggaattg gacttgatac tgataagtct tacctaccaa
     3781 attttcttca acatccaaac tccagacacc gattgtattg tccttatgat tataagagta
     3841 gctattgcct cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc
     3901 ataaacgaca acttgcactt ctgtcgctgt aggtgaccag agagaaaaat gagcctgatt
     3961 gtcctctaca cggcaaccca attctccttg gtaaccccaa tgatgatcaa aactagcact
     4021 gttaatggcc ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc
     4081 aggattttca gagtaataaa tcctatcatc gccttccaaa atccagacct ctgttaatag
     4141 gggatagtga ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa
     4201 attcaagctt tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata
     4261 atcttctttg taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt
     4321 gtcatattct ccattcttac gatggtaatg aatgcgcata gggtagttat acatttttta
     4381 tttttccttt ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt
     4441 aacagacata gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag
     4501 ccatgcctca tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc
     4561 gtctgcacct accacgacga ggtcggtctt tttagaaata ctacctgtca ctttggcacc
     4621 cagactttcg agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa
     4681 taccacggtc aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag
     4741 attgacccca gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata
     4801 agtctgaaga cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga
     4861 atctgcctga gacagatttt caattgaatg gaaatattga agtaaaagct gactaacctt
     4921 gcttccgaca tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga
     4981 tgcttggata gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag
     5041 gaaatcctct tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa
     5101 aagcttctca acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa
     5161 gtgaatcaag ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac
     5221 ttcatcttca aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag
     5281 tttttcttca gagacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc
     5341 agccttatat acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac
     5401 attgtgcagg gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc
     5461 agttggagtt acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc
     5521 tttttcttcg gcagggaact tgtaggctac tgcccacttt ggagccttaa ctgtaaaacc
     5581 aagttcttct tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg
     5641 cagattttcc cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc
     5701 agccaagatt cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt
     5761 ttcttggcta tcacgagttg aagggctggc ttcttgatag agaaacgttg caagattacg
     5821 cttggcaact actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt
     5881 agcaaattca ggctctccat tttcttggcg cacttggtta acttggtcaa aggaagcgcg
     5941 tggcatgtaa cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat
     6001 gtccttaaca cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt
     6061 taccccagca accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt
     6121 cagctcacaa atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc
     6181 tagctcctca cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt
     6241 ttcaaaacca tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg
     6301 ctctggataa gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc
     6361 tgaaaccgag ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac
     6421 taactcattc attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa
     6481 acgagaaggg cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat
     6541 atcaattttt caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca
     6601 ccacttccaa ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct
     6661 tttgcaatag gcataaatag aatagctaag gtaaaaattg tactcagtac tcttccaaga
     6721 aattcgctct caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata
     6781 aacaattcac aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc
     6841 ataaaaactc cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta
     6901 attttactag ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt
     6961 gcataggctc cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct
     7021 gcaaaaaaga aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc
     7081 cagatatagt gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt
     7141 ttctcttgaa cttctgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa
     7201 aaagtcagcg agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag
     7261 gaaagaacag gagagctaac acctacaacc tgcaaaacca gctctaggcg agaattatag
     7321 atcacaatct catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa
     7381 aaggcaaaag caatagcctg cacaatgtta gcaacaatca aagcgccaat catccagcta
     7441 tcattcctta tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt
     7501 aaaatcttac gacgagaaaa acgatctgaa ataactccgc caaagggatt gacgagaata
     7561 gatgtgacga gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata
     7621 gaagccaacc agacactatt tccataatca tagagcatat ttcccatttt attgatagcc
     7681 ccacggctaa tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa
     7741 actattgtat caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact
     7801 tttgacaaat ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac
     7861 atcaaaaata tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg
     7921 atataaggca aaacctttta aataatggaa aacattacgc tcataaagct taataccttt
     7981 gtcaataatc ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc
     8041 taaacaatgc tggtaacaat tgagggccaa aatcaacact aatctcttat ggcgactaat
     8101 ctcttggtaa aattcctccc tctccataac ttctctacca atccgagtga catagtctac
     8161 atcgtagaaa ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt
     8221 tttgaagaga taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc
     8281 tctttgacaa atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt
     8341 cgaactctta gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt
     8401 tgaatagtaa agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt
     8461 ccttgcctta tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa
     8521 acgggagact gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca
     8581 ggattcgcct gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac
     8641 ttttccaaga tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct
     8701 tcttcctgac gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca
     8761 tcgtttgttt ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt
     8821 tcagcttcta gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc
     8881 tgggcctgat agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc
     8941 tcagtctgac tcatttctgc tgttgctttc ttctcaacat agtagtcgta atctccaagg
     9001 tagagagttg aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag
     9061 taacgatcat gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc
     9121 acttccttac tatcaatatc caagtgattg gtcggctcat ccagaatcaa aaagttattg
     9181 ttttccatag aaaatttagc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg
     9241 actgattttt taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca
     9301 acttctggtg tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc
     9361 agcttgcttt gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct
     9421 cccttgataa aaggaatctg gtccacaata gacttgataa aggttgactt gccgatacca
     9481 tttggaccaa cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac
     9541 aagacttccc cgtcatagcc aacagctgca ttttcaacag tcaaaacaac attgcccgac
     9601 gttttttcag actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa
     9661 cgctccattt tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga
     9721 actagattgc gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag
     9781 ttttttgcct cagtagctag cttttgctcc ttcaactcaa caaaacgaga gtaattcccc
     9841 acatagcgat ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag
     9901 aaataacggt cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct
     9961 agccaggaga tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg
    10021 ggcttttcaa ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca
    10081 gcaattttca tctgccacat agactcgtca aacttgaatc cattcaaaat cgctcgaata
    10141 tcagcttcat aggtaaagcc gcctgcttgg cgaaaattct cagataagtg gtcgtaatct
    10201 gacatcagtt tatccaattc atcgccagac ttttcaccca tctccaactc catctgacgc
    10261 agttgtctct ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta
    10321 ttttcagact caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta
    10381 ttgatttctc cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta
    10441 cctgcaccat ttttcccaac aagagcaatc cgatctcgtt catcaacctg caggttgata
    10501 ttatcgaaaa gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc
    10561 ataagagtag tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac
    10621 aacttttata acataaaata aactaaatta tgtatatttt atattagatt ccttcactat
    10681 cttgttggat tttctaacca gctaatcttg tttcaaatag ttatcgcaca agtctattat
    10741 ttaattcttt tcattattta cgtacgtata gcagattgaa ataagatgag aacaaatcga
    10801 ttgggaaagt aaaattaatt tctataaatg ttttagcaat tgtttcgtac tattttagat
    10861 tcagtctact atgtacaata ttttcggaac attcaacttt ttaactctat ttattactag
    10921 atttcataat taaaaagcct actgaccaag ctagaaagct tgatacaata ggctttttaa
    10981 agactgatta tttaacagcg tctttaagag ctttaccagc tttgaatgct ggtactttag
    11041 aagctgcaat tgtcatttct ttaccagttt gtgggttgcg acctttacgt tctgcacgct
    11101 cacgaacttc aaagttacca aaaccgatca attgaacttt ttcaccagct gcaagatagt
    11161 cagctactgc tgcaaataca gcttcaactg ctgctgctga gtctttctta gtcaattctg
    11221 tagcttctgc tactttagcg atcaaatctt gtttgtttgc catgttaatg attcctccag
    11281 ataatttcta attaacaaat ataatcatat cctaaaatcc cttttaggtc aagttaaaaa
    11341 cgctatttct tccaatttta tttatttttt aggagtggta acgtatcaaa atagcccaag
    11401 cgttctcacc cgtgtgagtt tgaataatgg aacccgtttc caaaacagaa attggctttt
    11461 caacataagc ttgtaagctt tctttcatct cttttgccca atcatcacta ccagaatatg
    11521 aaattccaat ctctgctaca gcacgttcag aaagcgatgt tatcaactca tctaaccatt
    11581 ttttaaatgt tttagttcca cgacctttaa ccattggctg caattcatgg tctttcattt
    11641 gcatgacaac acggatattg agaagggagc tcaacaagcc agttacacgg ccaattcgtc
    11701 cacctttgac aagattttcc aaagttgaaa caccaatata aagctctgta tggtttttaa
    11761 cctcttctac atgagataaa attgcctcca tatctttacc ttcttgagct aacttcgcag
    11821 cctcaacaac ttggaatttc agggcttggt cagtgaagga actatcaaca acaatcacat
    11881 ctgcagtaga taggctagca ccttggcgtg ctgcttctac cgtacccgaa agagcatggg
    11941 acatatgaat agcaagaatc tggccaccat ctttgcatag gtcttcaaaa atctcagcaa
    12001 agacacctac aggtggctga cttgttttcg gaagattctt actttcttgc atcaactgaa
    12061 gaaatttacc ttcttctttc aaatccgcat cagaataaac aacattatca atcattacag
    12121 ataatggaac aattgtaata tctaattgct ttactagttc aggttcaata gtaacagatg
    12181 aatcggttac aatcttaatt tttgtcatag tatcaatctt tctattttag gattcagatt
    12241 ggtttcctta cttttaatta tatcaaaaaa aagattaaaa atcctaatgg agtcaatcaa
    12301 attttccgta aaatttgata taatcaactt ataagaaaag aggtgtccta tgattaaaaa
    12361 aatttacccc atttttacca ttttactagg tgctgctatt tatgcttttg gactgactta
    12421 ttttgtagtt ccccatcatc tctttgaagg aggggcgaca ggcattaccc tcatcacctt
    12481 ttatcttttt aaaatccctg tttccctcat gaacctgctg attaatattc cccttttcat
    12541 cctagcttgg aagatctttg gagccaaatc cctctattct agtttactag gaaccttagc
    12601 tttgtccgcc tggttagctt tttttgagca tattcccctt catattgatc ttcaaggtga
    12661 tttactaatc acagccctta tagcgggaat cctattggga attggccttg gaattatttt
    12721 taatgctgga ggtacaactg gcggaactga tattctagct cgtattctca acaaatacac
    12781 tcatatatcc ataggaaaac tgctctttat cttagatttt tgtattctca tgttgattct
    12841 cctaatcttc aaggatttga gattggtttc ctacacgctt ttgtttgatt ttattgtttc
    12901 tcgtgttatt gatttgattg gtgaaggagg atatgccggc aaaggcttta tgattatcac
    12961 aaaacgtcct gaccaacttg ctaaggcgat taatgatgac ctcggaagag gtgttacttt
    13021 tatttctggt caaggctact atagtaaaga aaatttgaaa atcatctact gtattgtcgg
    13081 aagaaatgaa attgtgaaaa cgaaggaaat gattcatcga atcgatcctc aagcctttat
    13141 aactattaca gaagcccatg aaatcctagg agaaggcttc acctttgaaa aagaataaaa
    13201 agaggtaatg tcgtgacctc aaaagttaga ctaaatcatc tatcttttgg gttacagaca
    13261 acctcttttt tgttttattt actcaagctc ttaagaccaa ttccgagtta cttcttcatc
    13321 agcctttaac tgatccacta attggtcaac tgagtcaaat ttggtcatat cacgaatgcg
    13381 atcaagccaa taaaccatga cggtttcccc ataaatatct tgattaaaat caaaaatatt
    13441 gacttcaaaa cgtgcttctt ctccatcaaa ggtcacattt ttcccgacac tagccatagc
    13501 acgatacttc tgtctttgaa tctcaacatc aacgacataa acgccatctg ctggcatata
    13561 agtacggtct aaaagcacta aattcgctgt cggataacca attgtacgac cacgagcatt
    13621 accatgaact accatacctc ttgatggaag cggtgccccc aaaagttttc ctgcttcttt
    13681 cacatttcca tctaaaatag cttgacggat acgagttgaa ctaatctttc ctttctcatc
    13741 ttctacaggt ggaacaatga taacttctcc atcaaagtaa tcctttaaat cttctgctgt
    13801 ttttttgtca gaaccaaatg tataatcaaa acctgcaaca ataattttgg cattcatagc
    13861 cttgatataa gttgcaaaga attcttgtgc agtgagacta gcgaattgac tactaaaatc
    13921 aaggagatat aattcttcta caccttcgcg ctttaatttt ctttcacgtt cagcagggtt
    13981 caaaatatgc aaaaacaaat ctggatgata aggctctaaa gcgatctttg gagattcatt
    14041 aaaggtcata acgacgatag gcaataaatc ctttctcgca gccttgttgg caacacgaaa
    14101 taattcttga tgccccttat gtatgccatc aaaatagccg agaacaacga ctgaatcaga
    14161 tggtgtgcca atatcttttt ggttttttat aggaatagta ataatcataa aataattata
    14221 tcatagcgat agctatttct ggaacagaaa atctgaaatg ttgttttttt cacatgaagt
    14281 gtacctgttt tcaaaaagca ctttattcta tcgttgctta actatgaact ttgcaatatt
    14341 cttctcaaaa acttgtagga catcttcaaa attttgcaag gagtgattag acttgttcgg
    14401 taactataaa gtgtcatact atgcttatgt atgaaaaagc aatgcaacta actcctgaga
    14461 actttaaatt actaattggt gccgaaaagg tagaatttag aatagaggta cacctatggc
    14521 tgtaaaattt acaaaatgag acaacttggg caagatgttt gaagaatttc ctaaactccc
    14581 tgatttgaag caagtcactt tccctgatga caaagaaaaa agccaaagca ataaagaaaa
    14641 actagatgac tgctttccaa caactcccat ctagtgtgct tcagactggg ctatttttct
    14701 ctccatctgt tagcttggat tctcagaccg tttcagctaa agaatatctt ttcctttatc
    14761 agaaggaacg gctcaagcca ttcagacaag tgaagggacg acaagccaat atttgaaacc
    14821 agatagcagt tcttatagtc aattgaaata aaatctgaag aaatcgagta ggaaactcaa
    14881 atcaattttt agcagtgttc tattccagat tcatactcaa tgaaaattaa agtgcaaact
    14941 aggaagttag ccgcaggctg tacttgagta cggcaaggtg aaactgacgt ggtttgaatt
    15001 tgattttcga agagtatcaa tccactatac atattaaaaa gtatgggtat caaaataaaa
    15061 aaacaggctc tccgaaaact cagaaagcct tattttaagc tgtttctagt ttcctcacct
    15121 ttacatttca aggttcggga taaaaggttc aatggacctt tttatttagc gattgggtaa
    15181 acagaaactt gttttttatc gcgtccttta cgttcaaagc gtactacgcc ttcaacttta
    15241 gcgaacaaag tatcgtctcc accacgacca acgtttacac ctggatagat gtgtgtacca
    15301 cgttgacggt aaaggattga tccacctgtt acagtttgtc cgtcagctgc tttagctcca
    15361 agacgttttg cttgtgaatc acgtccgttt gatgtagaac ctccaccttt tttgtgggcg
    15421 aaaagttgca agttgttaag agtcattttt aacataatgt tttcctccgt gttagttttc
    15481 tgtgataact ctggtttgga cgaactcaga agagttctcc gataagtttg ccatacctaa
    15541 gaaaaatgat tcaaagaata actgggtcat ttctctctgg tgtgaaggaa gatcttttgg
    15601 tatttcaacc atcagatagc caccttcatc ttcgtttaat tctaggattg gttcatagcc
    15661 tgcaaatttc tcaatagaat tgataaagtt aatggcaagc gtagaaaccg atgcacacac
    15721 gacatctaag ccgtattcgc cactctcggc gtgtccagta atttccgcac tcctcagctc
    15781 gccatcttcg gctctctcaa agactgcctg tatcatgtgt tctccttaaa attaagcgtt
    15841 gattgcgttg atgacaactt ttgtatatgg ttgacggtga ccttgtttac ggtggctacc
    15901 ttttttaggt ttgtacttgt aagtaaccac tttcttttgt tttccttgtt tttcaacagt
    15961 tccaactaca gtagctccag caacaagtgg agttccgaca acagtgtttt caccaccaac
    16021 aagaacaact tcgttaaaag taacttcttg accagcttca acgttcaatt tttcaacgta
    16081 aactgcttga ccaacttcaa ctttaacttg ttttccgcca gttttgataa ttgcgtatgt
    16141 gctcattatg cacctcctat gatttttatg ggtttccccg attttttgtg aagactcgcc
    16201 tagcatcgtg ggacgaacca cttaaacttg aataatcaag caacgatgtt cgtgcggttg
    16261 cacaggatcg tgcatagtca actcttcaag tatagcatat ctcctatttt cttacaagta
    16321 ataacaccta aaatcaagct ttttctttta cttttttctg ccaagaggca aaaagcatgc
    16381 tgaggtaaaa aacgctcatc ataataggaa caccaagaat ggtcttttca tgatagaaaa
    16441 tcgtcaaata ggctgaaaag acaacgccaa ggacaaaact actaagcagg ctaacaaata
    16501 tgaatccttc acgcaaaaaa ggagtgtgct tggttcggaa ataatctcca aaagccagca
    16561 tggtccgttt gatattccct gtcataaaag cgttattata ggcaataccc gacacttctc
    16621 caaaagcagt tgtcaccagt cccatacaga aggccaaggg cggcactaga tagatattat
    16681 ccacagtttg cggcacaaaa gcaataatga ttgataagat tgccaaggga atcaaggaca
    16741 gaataggttt tttcacaatt ctcaattttt ccttataaat cgttaataaa aagactccca
    16801 tcataaacgc tagcaaggtg agaaccttgt ccctaacatc cgaaacatta tttttaatta
    16861 attctactga aagaaagaca acatttccag tttgtccagc tacaagggta ttcccgcgaa
    16921 caataaaagt gtaagcatcc acatatccag cacaaaacgt caaaaaaagt gctaaccttt
    16981 tagactgacg tgatattttt cttataggta ataacctcat tttacctccc attgtatttt
    17041 ctcttagaaa tattgtacca ttttctttct aaaaaatcgt aggctaccat ttagatttta
    17101 ctattagcat aaaaataata atagacaact atttatccaa aaatagatag atgtaacatg
    17161 tttgcaaaca aagcatacga acctttagta aaatcatttc catgaaacta gaatagagcc
    17221 ctcttagcaa aaatcattat tttaatttat ttctaatcac tccttgacat aaataactct
    17281 caccaataaa agactatgtc ttaaaaaaat ggtataataa aatcaatact tgggcttgat
    17341 ggctctgcta ctaataacaa ttaggagaga aaatcaggca cttgttaaca acaaggatta
    17401 tccccttgag atgaaaggaa ctttagaaat cttatgatga acatgcaaaa catgatgcgt
    17461 caagcacaaa aacttcaaaa acaaatggaa caaagccaag ctgaacttgc tgctatgcaa
    17521 tttgttggca aatctgctca agatcttgtc caagcgacct taactggcga taagaaagtt
    17581 gtcagcattg atttcaatcc agctgtcgtt gacccagagg accttgagac tctttctgat
    17641 atgaccgttc aagccatcaa ctctgctctt gaacaaatcg atgaaactac caagaaaaaa
    17701 ctgggtgctt tcgctgggaa attacctttc taaaaacaag gagctagaac aatgcttgtc
    17761 gataacaaag gctaagaaag gtgcaaaaat tataaaaaac gcataatagc aggtgtcaaa
    17821 gcactcaata ttatgcgttt tctcatgaaa aaattctctt ttcatactca tttaaaatca
    17881 aaaagggaat ttatcatttt acggacatgt atattacaga tttctatagg tcgtatatag
    17941 acaggatatt atcgcttaga agttgtcctt tttgacacca atcagtaatt tagttctcag
    18001 gagttaatgg aagtgctttt cgcacatagt ttcataacta cagtatagca tagtatatca
    18061 ctttatagtt ttcactattg atgaactgct tgagctgctg tgatgagggt caacttgtaa
    18121 acatcgtctg cattacatcc acgagaaagg tcgttaactg gtttgttcaa accttgcaaa
    18181 acaggtccta cagccgcaaa accacccagg cgttcagcca tcttgtaacc gatatttcct
    18241 gcctcgatac ctgggaagat gaagacattt gcttgaccag ctaccgtact tcccggagct
    18301 ttcagagctg cagtttcggg aacaaaggcc gcatcaaatt gcaactcacc atcgatttca
    18361 aggtcaggac gcaagtcgtg agcaatttta gttgcttcaa cgaccttatc aacgctttca
    18421 ccaaaccctg aacctttagt agaatagctc aacatggcaa ttttaggttc gatgccaaac
    18481 atcttagctg tgattgctga gttgatggca atttcagcca aggcttctgc atctggattg
    18541 atattaatgg cacagtctcc aaataggtaa cgttccgtac cacgaaccat gaggaaggct
    18601 cctgaagtac gagttacatt tggacgagtt ttgatgattt gtagagctgg gcgaactgtt
    18661 gaagctgttg agtgaatcgc tcctgacacc attccatcaa ccaagcccaa gtaaaccaac
    18721 atcacaccaa agtagttgac atcttcaacc aaaaccttgc gtacatcttc ttcagtcatt
    18781 ttgcccttgc gacgctccac caaggcagaa accatttctt caaattgagg ataatgttga
    18841 gggtcgatga cctcataacc atccatgatt ccttcaattt caagataaat tttaattttt
    18901 tcaggatttc caagcaaaac aggaatcact tctgtttctt ttactaagcg ttttgttgct
    18961 tgaagaatac gaggctcttc cccttcaggg agaacgatac gagcattttt accaacaagg
    19021 ttggctttga gactttcaaa aacttccatg agttttctcc tttaagataa taattatact
    19081 ttgagacagt ttttatagag tattagttga taactgggta ataaggttac tgaaatcatc
    19141 cggcaaggga ctttctaact gcaagtcttg ctctaaaaat ggatgataaa aggataggta
    19201 atggcaatgc agagcctgac gttgaatacc atcttccaga ctaccaccat acaaatcatc
    19261 tcccagcaaa ggaaaaccga tatgagaaaa atggactcgg atttgatggg ttcgaccagt
    19321 gtgcaggtga atatagacca agtgaatatt tccataagaa gctacaatct tgtatgaagt
    19381 atgggcatac tttccgcctt tagccactcg tctggtaata atggaatctt catcacgcgc
    19441 aatcggagca ataatttccc cttctggctc caaatgtcca tctcccttaa ccaaagcaaa
    19501 gtagcgtttc tcgatagatt tcttctgcaa ctgcttgtct aatcgtgcat gggcataacc
    19561 gtgcttggca aagagcatca agccagaagt gtccctatct agtctggtaa caatgtgaac
    19621 ctgctgattt tcataatttt gcttgacata gtaacccttg ataaaattgg caatggtatt
    19681 agagtgattg acactaggaa tagaagccac tccatagggt ttattcaaga ctagaaagtg
    19741 gtcatcctca tagagaatat ctaatggatg ctcaatagcc tccaaggttt caaagccttc
    19801 ctcagcggga atgtaaatgg taacgtagtc tccaacgtcc aatagatacg ttgcattttg
    19861 cggttgatta ttgaccagaa tagctccacc tcgaaactta atcttggcca gcaatccctt
    19921 agaaacctcg tgctttttta aaaaggtctt aaccttgaca tgttcatctg cgataaattc
    19981 aaacctcatt catccacctc accgataaag gcatccttaa cacggttcca gaaactggta
    20041 tggctaggag tcgcgacaaa gtgaatctta tgatggtcga tttgatactc aatacgctca
    20101 atattacgga aagaataaac gctattgtca accgaaatag tatgataatc gtttcttgtt
    20161 ggaataagtt caatcttatc cttcttaggc acaataatgg aagagcccag tgttcgatag
    20221 acacgattat taaggctggc aatctccgtt aattgcaaag cttcaatggt agggtgtaaa
    20281 acagcaccgc caagagactt gttataggca gtactaccag tcggtgtcga aactgttagc
    20341 ccgtctccac gaaaacgttc aaagggaaca ccatttatta caatatctgc caccatggtt
    20401 cgatcagacc tgcggatgct ggcttcgttg agtgctctga aaatcttaac ttcaccattt
    20461 tcgagaaaga ccttcacatt cagaacaggg taagaaaccc ttgccccagt atctagctgc
    20521 aaattagtca ctagcttgtc caactcaaaa tcacgataat ctgtatagaa gcccaaatgt
    20581 ccagtatgaa gaccgataaa gcggaccttg tcaagctgat tttcgtactt atgaaaggcc
    20641 gacaagagca taccatcccc gccaatggaa atgacaatat ccggattggt atcattgagt
    20701 ataaactgat ttctcttcaa acgatctcgc aattcataca aaaccctttg actctgcggt
    20761 tttctattgg ctatcagatc aattcgttta cctgtattct tcatctgtat cgtcactgtt
    20821 tcctacaccg tcatttaatt ttctactcaa aggatcaaaa agtgcctggg cttcttggat
    20881 atcatcacga atttcaccca tttcttcatc caactgatgg gcgattctag ctgtaatttc
    20941 cagtcgcttc ttaatctcat ctgggaaatc cccttggtac ttgtagttga gagaatgttc
    21001 tatcgttgcc cagaaattca tggccaaagt acgaatttga atttctgcca aaatagtctt
    21061 agctccattg atggtatcaa ccgtatattc tactaccaca tgataggaac gatagcctga
    21121 tgcttttcta tgagtaatgt aatctcgctc ctgtatgatt cgcatatcct gacgcttgtg
    21181 caaaatatcc actacttcct tgacgtcatc tacaaactga accatcacac gtaagccagc
    21241 aatatcctgc aaatcgtgtt ccaaggtcgc ataagtaatg ccacgacgag ccattttttc
    21301 tttgatgctc tcaattggct tgactcgacc ggtcacaaac tcaattggag aatgcttatt
    21361 ttgcttacga tattgcttac gaataccacg aagtttaatc tttaactcac caacagcttg
    21421 aatgtaagga tctagaaatt cttcccattc taaggtcata tattctccct tgttctcata
    21481 ttatccgtca aaaatatctt tgattttttc tccagattca tatacaataa atacaatgct
    21541 tattatacca taaatccgct ttcaacgata aaaaaaggta agaaaaatga aacatttaga
    21601 aattgaattg aaaacactat tgaaaaaaga tgaatacaat cgtctaaaag accagctcac
    21661 aggtgtcact cctgttcttc aaacaaatta ctacatcgac acgcctgatt ttgaactgcg
    21721 agaaaagaaa gtcgctatgc gcattcgaac ctttgaagac tgggctgagt tgacactcaa
    21781 agtcccgcag agtgttggaa acatggaata caaccaaaaa ttgcaactaa aagatgctga
    21841 gaactatctg agtaaggaag aacttcctca agggctagta ctggatgaat tggcgaaaca
    21901 tggtatccaa agtaagaact ggcaggttct tggttgtcta acaacgcttc gctatgaaat
    21961 gaaaacagct attggtctca tggcactgga tcagagccga tactttgata taacagatta
    22021 cgaattggag cttgaagtgg aaaatcatga gcaaggcaaa caggatttcc gacaattttt
    22081 agagaaaaat cagatttcct accaaaaagc tccttcaaaa ttggttcgat ttgtcaaaag
    22141 tatgaaaaat agctgaaata atctccattt tttggtaaaa tagaaaagat aaaaatacac
    22201 aaatcccagt tcatatatgt aaggtaaata taactaggat ttataaagtt tacagaggac
    22261 ggtctataat gtcagataga aaaaacatga aacttttcgc actcaactct aaccaagaga
    22321 ttgcacaaaa aattgcccaa gctgttggtg tcccacttgg aaaactatca tcacgtcaat
    22381 tttcagacgg agaaatccaa gtaaatatcg aagaaagtgt ccgtggttat gatgtttaca
    22441 tcatccaatc aacaagtttc cctgtcaaca accacctaat ggaattgtta atcatggtcg
    22501 atgcttgtgt gcgtgcaagt gcccacagta tcaacgttgt ccttccatat tttggctatg
    22561 cacgtcaaga ccgcattgct tgtcctcgtg agccacttac agcaaaacta gttgccaata
    22621 tgctggttaa ggctggagtt gatcgtatcc tgactcttga tttgcatgcc gttcaggttc
    22681 aaggtttctt tgatattcca gtggataatc ttttcactgt tcccctattc gcaaaacatt
    22741 actgcgataa aggattgctt ggttcagatg ttgttgtcgt tagccctaaa aattcaggtg
    22801 tcaaacgtgc gcgtagcctg gctgaatatc ttgatgctcc tatcgccatt atcgattacc
    22861 ctcaagacga tgcaactcgt aacgaaggtt atattattgg tgatgttgaa ggtaagaaag
    22921 ctatcttgat tgatgatatt ttaaatacag gacgtacctt ctctgaagct tctaaaatcg
    22981 ttgaacgtga aggagctaca gaaatttatg ctgtttctag ccacggtctc ttcgtcgagg
    23041 gagctgctga gcttcttgac aatactaata ttaaagaaat tcttgtgact gattcagtag
    23101 caacaaaaga aaaaactcct aaaaatgtat gctacatcac tgctagtgag ttaattggcg
    23161 atgctatcgt ccgtattcac gaaagaaaac cagtcagccc actctttgcc tacaataaaa
    23221 agaaataagg tgattctttg atttatttgg acaatgctgc aacgactcct atgtcagcag
    23281 ttgctatttc agctatgacc aaggttatgc aagaaaccca cggaaatcct tctagtattc
    23341 atggtcatgg tcgtcaagct ggcaaactct tgcgagaagc ccgtcaggaa ctagcccagt
    23401 tactaaggac aaaacctcaa catatctttt tcacttctgg tgggactgaa gccaataata
    23461 ctaccatcat tggctactgt cttcgtcacc aagaacaagg aaaacatatc atcacaactg
    23521 ccatcgagca ccatgctgtc cttgaaacaa ttgattactt ggttcaacac tttgggtttg
    23581 aagcaaccat tatccagcca gaaaatcaag aaatcacagc ccagcaaatt caaaaggctt
    23641 tacgtgacga tacgattttg gtttctacca tgtttgccaa taatgagaca ggaaacctac
    23701 tgcccatcgc tgaaattggc caaatactca agcaacaccc tgctgcctat catgttgatg
    23761 cagttcaggc tattggtaaa atcccaattc attcagaaga attgggcatt gattttctca
    23821 ctgcttctgc ccacaaattc catggtccta agggaatcgg ttttctctac gcatctagca
    23881 tggactttga ttcctatcta catggcggag accaggaaca gaaaaaacgt gcaggaacag
    23941 aaaatctgcc tgccatcgta ggcatggttg cagccctaaa agaagaccta gaaaaacaag
    24001 aagaacattt tcaacatgta caaaatctag aaactgcctt tctggcagag ctggagggca
    24061 ttcagtatta cctgaataga ggaaaacatc atctccctta tgttctcaat attggatttc
    24121 ctggtcagaa aaatgacctc ttactccttc ggctagattt agctggaatt tcaatctcta
    24181 ctggctcagc ctgtactgca ggcgttgtcc aatccagcca tgttcttgaa gccatgtatg
    24241 gcgcaaattc agaacgcttg aaggaatccc ttcgcatcag tttgtcgcca caaaataccg
    24301 ttgaagacct acaaaccctc gcaaaaacct taaaagaaat tatcggaggt tagccatatg
    24361 gcatttgaaa aaatcattca gttaaaaaat tgtcgttacg attacactct tagcccttct
    24421 gttaaaaaat tcaccctcaa agataacacc ttttttgaaa ctaaggttgg taactatgaa
    24481 ctgactcgcc ttttggaaaa agtgccaaac agcggtgaag gcttccaact caaaatcatc
    24541 attaacaagg aacttacagg ggctaaaatc aatatcactg acaagtttgg ccttcgtcta
    24601 gttgatattt tcaaatcaga agaccaccat attcatcagg aaaaattcta cttcctcatg
    24661 gatagcttgg tagaacgtgg tgtctttaca aaatcggaaa gatagagcca aaatgtttga
    24721 actgacctat aaggactgct atcatgtaga gcgtactctc aagtatgagg atcatgaggc
    24781 tctcatgttg actttgtcag gatgtgtaac cttaccagat acactttatg tgacttctct
    24841 gacttttagg ggccaaaaag tttatcaggg tctggtcgga gacctctacc gttttctatc
    24901 tcatgcagat tttttacatc aaaactaaga tttttcttag ttttttctta tttttgttga
    24961 ttttttcaca atgtttctat aaaatagaag aatagaaagg ttgtgatttt gtgaaagata
    25021 aacagtttgc tattccaaaa gctacagcaa aaagactctc tctctactat cgaattttta
    25081 agagatttca tgcagaaaag attgaacgtg ccaactctaa gcaaattgca gaggctatcg
    25141 gtattgattc agcgaccgta cgtcgtgatt tttcctattt tggtgaactt ggtcgtcgtg
    25201 gttttggcta tgatgtcaaa aaactaatga cattttttgc cgatttgctc aatgacaact
    25261 ctattaccaa tgtcatgctg gttggtattg gaaatatggg ccatgccctt ctccactacc
    25321 gcttccacga acgtaacaag atgaagatta tcatggcctt tgacctagac gaccatcctg
    25381 aagtcggtac ccaaactcct gacgggattc ccatttacgg gatttctcag atcaaggata
    25441 aaatcaagga tgctgatgtg aagactgcta tcctaactgt tcccagcgtc aagtcacaag
    25501 aggttgctaa tctcttggtt gatgctggtg tgaaaggaat tctcagtttt tcaccagtcc
    25561 atctgcattt accaaaagac gtggtcgttc agtatgtcga tttgacaagt gaactccaaa
    25621 ccctcctcta cttcatgcga aaagaggatt agaaagcgaa aatcatttta tgaaaaaacc
    25681 agttattggg attacaggaa acgaaaaaac tcatccagat gatgacatca tgatgagcta
    25741 cgcagcaaaa ggctttgttg aaggcgttaa agatgctgga gggattccca tcatcctacc
    25801 gattggtgat caagaaatgg cctgccacta tatcagtttg attgacaagc tcatcttgac
    25861 aggtgggcaa aatgtcgatc caaaattcta tggcgaaccc aaaaccattg atagcgatga
    25921 ttatcacctt caaagagata tcttcgaact ggccctcatc aaggaagcta ttaaacagaa
    25981 aaagcccatt ttctctgtct gccgtggtac ccaactcttt aacgttgcca tgggtggaac
    26041 tttgtaccaa gatatcgaag accattggca ggattcttct gttgagtaca caactcaacg
    26101 cttggtaaca gaaccagata ccgttctcca agaaatctat ggagaaatct ctcatatcaa
    26161 ctccttccac caccagagca tcaaggactt agcaccaaat ttaaaagttg tggctcatga
    26221 tcctaaagat ggtatcattg aggctgtcat gagtacggat gatgtcgcct ttctcggtgt
    26281 ccaatggcat ccagaacttc tttttgaaaa tcgtcccaaa gataagaaac tctttgacta
    26341 tgtcgttaat gaactttaga ttaaatctgt cttttcacga taactaaagt aattagaatg
    26401 agagacaatc aaatggtcca agagaacaat ccccatcagt tcgcaggctt ctttaacaag
    26461 tttagtgaca tgatcatcat tttggctagg cgctaccgct cctgaaggat gattgtggac
    26521 caagataaga gaagtcgcca tatgcttgat tgcatagtgc agaatctctc gcggttcagc
    26581 gatactacga gttacagaac cgataaaaat ggtctgctga tggatgattt gattttgagt
    26641 attgagatag agtgccacca ggtgctcttg ttttttatcc cctaattcct gctgcatctt
    26701 cttggccaac ttttgactgc tgagaatact ttccatttca agagtctcgt gtttgtgaat
    26761 acgatgcccc agttcaatca tagcttgtaa ttctatggcc ttaacacgcc caataccaga
    26821 caaactctgc aattcctgca gggtcatttt tttcaaatcc gttaggcttg aaagattgtt
    26881 caagactttt tgggcaattt caaaaacgct agcttgacgt gttcctgtcc tgagtaaaat
    26941 agctagcaac tcttggttac taagcgcttc aactccttcc ttggccagcc tttctcttgg
    27001 taatagtgaa tcttcttgga atgaaatact gtacataaaa atcctcctca ctttattatt
    27061 cgtgagaagg atggaaaatt agattttttt ctcaattgga gccacactgg ctaaaagttt
    27121 tttcaaacct acttctggga aattgatttt caattcctgc ctagcaccgc tacctgaaac
    27181 ttccagaaca gttccctctc cccatttctt gtggagagca atgtcaccaa tggaccaatt
    27241 tgcctcgcta gatgctgatt ttgcgccagc tgtaaattga ccaaatggaa gaccgcttga
    27301 ctggattgat tttggggcag caccgcgttt acggtcttga agagcctgag ccaaactcat
    27361 accttgacca aaggaaatac taccactgct atatgatgcc ttaaagcttg tatttgcagg
    27421 acgagccaga ccttgatact caagcaagtc tgaactgatt tcgttaataa aacgagtcgg
    27481 acggttataa ttggtacgac caaaaagcaa gcgtgagttg gcattggtca gatagagaat
    27541 tttctctgca cgcgtgatac ctacataggc tagacggcgc tcttcttcta attcatctgg
    27601 atcttcagtc gcacgactaa gtggaaagac attttcttcc atcccaatca aaaagacaac
    27661 tggaaattcg agacctttgg cagcatgcag ggtcatcaag gtcacttctg atgtctcctg
    27721 actacctgaa tctgtgtcgg caatcaaagc caagtcattt aagaaacgac tcagtttgtc
    27781 cagaccagtt tcctcttctg tcacatccgt ggtgtcatca aagttcttcg taacagaaag
    27841 aaactcttcg atattttcaa cccgtgcctt gctttctaga gtcgcttggg cgttaagaat
    27901 atcgacataa cctgtttttt ctaggacgga ctcaaccaac tctgtaatgc ttaagtggtc
    27961 tagctgctcc cgcaaatcaa gcatcatatt ggcaaaatcc cagatagatt gggctgcctt
    28021 acccttgata ccagacaaca taatattagc agaagcatcc agcatagaca tattttgcaa
    28081 atttgcaaaa tcacggattt tctcaactgt acctagacca attccacgtt taggctcgtt
    28141 gataatacgc tcaaaactaa tattgtcact caaattagca ataaggttga gataagcaat
    28201 aatatcgcga atttccttac ggctgtagaa tttggttccg ccaaccatgg tataaggaat
    28261 gttagacttg agcagggctt cctcaattgt acgggactgg gcattagtcc gatagagaac
    28321 tgcaaaatcc ttatgaagga agttttgact gcgactaagt tcatcgatgg ttctggctac
    28381 aaatacagcc tcatccagct catcatcggc acgatagtaa acgatttgct ccccatcagc
    28441 gttttgagtc cagagatttt taggacggcg atttttatta tttttaataa cctcgttggc
    28501 cgcttggaga atggttttgg ttgagcggta attttcctcc aacaaaacaa ccttggcttt
    28561 ggggtaatcc ttttcaaagt ccaagatatt ctgcatatca gcaccacgcc aaccgtagat
    28621 agactggtcc gcatccccaa ccacacagat atttttaaaa cgggaagcca agagtttgac
    28681 caattggtac tgagcgtggt tggtatcttg gtactcatca acgtggatgt attggaattt
    28741 ttgctggtag taggtcaaaa catcaggatt ttgatcaaag agacgcaagg tcagcataat
    28801 caaatcatca aagtcaacgg attcagactg acgaagttct ttttgatagg ctgtataaca
    28861 ctgggccaca atttgcgtat acatatcgcc agcttgggca gcataagcaa catcatcaat
    28921 caaatcattc ttagcattgg aaatggtccc caaaatagtt cgttcattcc attttttagg
    28981 atccaagttc aactgtttga gaatacgttt catgagcgtt cgctgttcac caggatccac
    29041 aattgtaaaa ttacgattgt agccaatatg gtccgcatcg cgacgcaaaa tacgcacaca
    29101 catggagtgg aaggtcgcaa tcagacagtc ctgagtcgct ggattgaggc tataagcacg
    29161 ctctttcatc tcacgcgcag ccttgttggt aaaggtaatg gccaagatat tccaaggatt
    29221 gaccagcttt tcatcaatca aataagcgat acggtgggtc aaaacacgag tctttccaga
    29281 accagcccct gccatgatta gcaagggacc ttctgtcgtt tgcaccgcct cagcctgacg
    29341 gtcattcatt ccatttaata atgcgttcat cttctcttcc ttactcttga agtcaatatt
    29401 tctattatat cagaaatcag ggaaaataga aactttacgg ggagtagcaa aatatagtgg
    29461 attgaaacta gaatactaca ctgtgggttt ctaaaacact cgactttttc acccaatttt
    29521 ttcataaact agctcaatac ctcaatagac ttcctgcaaa actagaatcc tagttcatga
    29581 ttgataatac cagcaatcaa attcattcgt aatccgaagc gtttacgatg atttcgatag
    29641 gttgttgaaa acattttaaa cgtttttact ttggcaaaga tgttctcaac cttgcttctc
    29701 tccttggata gcgcatggtt acaggcttta tcttcagctg ttagcggctt gagtttgctg
    29761 gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata accactgtca
    29821 gccaagattt taccagcttg tccgatattt ctgcaactca ttttgaacaa cttcatatca
    29881 tgactatagt tcacagcgat atccaaagaa acaattctcc cttgacttgt gacaatcgct
    29941 tgagccttca tagcgtgaaa tttcttttta ccagaatgat tcgctaattc tttttttagg
    30001 gcgattgatt tgtacttccg tcgcatcaat cattaccgtg tcctcagaac tgagaggagt
    30061 tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc tccgacggat
    30121 taagttgctt tcgtgaatac caaaatcagc cgcaatttgt tcataagttc gatattctcg
    30181 cacatattga agagtggaca taagaaggtc ttctaggctt aatttaggtt ttcgtccacc
    30241 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aatatctctt caaaagtcgt
    30301 gcgctgaaca ccaacaagac gcttaaatcg tgcatcagtt agttgtttac ttgcttcatc
    30361 attcatagaa ctactatacc atattttatt tcgcaggaag tctaatctaa aaaaggtaaa
    30421 tttaagattg gcaatacgaa cgttaaacag aattccattt ctctttttag aatcaaaacg
    30481 acaatattgt ggaatctcta caggaacaat agactgcgac actaaaatat cctctcttag
    30541 ttttacttta ctaatagtat ataggaggag agccctgaat cctagaccct ttgttatgat
    30601 gcgcttacaa acagagttgg aaaaaatctt aaaagcagaa aaacgcatga tatcagcccc
    30661 taacacttga tacaatgcgt tttattatga aaagatctac tggatttttt atcaaaataa
    30721 acttccagta gtcttttcac tttttattaa taagttcctt cttcaccttg gctagtcaag
    30781 ataacaggtc catctttcgt aatgacaaat tggtgttcat actgacatga caatccaccg
    30841 tcaatggtct tatgcgccca accagttttc atatctgtat caatttccca atcgcctgta
    30901 ttgatcattg gttcaatggt taagaccatt ccttcacgaa gacggagtcc acgacctgca
    30961 ataccatagt taggaaccat tggttcttcg tgcatagttg ggccaacacc atgaccaacc
    31021 aaatcacgca ctacaccgta accacgactt tcagcgtatt cttgaatagc cgcaccgata
    31081 tcaccgatac gatttccaac aacagcttgc tcaataccct tgtacatagc ttctttggtt
    31141 acatccatca agtttttgac ttcttcggac ggtgtaccaa cagcataagc ccaacatgag
    31201 tctgctaaac caccagaata gctctgagtg tattttttca tttgttcaac attgttgaag
    31261 tttaattttg agacatttag gtcagattta gcaatgggac ctcccaaaac catatcaact
    31321 ttgagcaaat caccatcttt caagatataa tgacgaggga aagcgtgagc cacttcatcg
    31381 ttaagagagc aacaggtagc ataaggatag tccatcatgg caccgtcaac cccaatctga
    31441 agtggaagga aattttcttc tttacaacga cggcggacat attcttcaac ttcccacata
    31501 tctacgcctg gcttaatcaa atcacgtaag cctatatgaa tacttgctag aaaatcacca
    31561 gccttgtcca tagcttcgat ttcacgagct gattttaatg ttatcatctt ttctcctagt
    31621 ttctaattaa ttttaacagt cacatttgct tttgaaacaa tctggtgacc atgataaata
    31681 tcgtaatcaa ttatagctga ccgtctcgta tgatgaataa tccgtgcctg aatgcgcaat
    31741 atatcatcta tctgaacagc ctgcaaaaag tagatcagca tctgctcgat aatgagattg
    31801 cgaccactat taacaactaa atcttgggtc atgtgggtca gaatttctgc caatacacca
    31861 ttagccaaaa ctccattttt ttctagcata aagggttcca ctgtaatgac tacttcatca
    31921 tggtgataag agagcttttg tccaatctgc tcagaaaaag ttggtagagc cgaaacttgg
    31981 gaacggctca tcttctccat gacatctcgt cgcgtcacaa cgccaagcaa agtttgattg
    32041 cttcgaacaa ctggtaccat ttcaaagtct tctgcgatca tccgttgact cacattggca
    32101 atatttgtcg ataatccaac caaaaataga ctacgagaca taaccttatc aattgtcgtg
    32161 cttggtgatt tatcaccagc gtctctcatg gttacaacgc caacaacgac ctgatgttga
    32221 ttgataacag ggaaacggct gctacgattc ttacgaacca agtccaaata atctttaact
    32281 gtatctgtct ctctcagaaa accatactca tgactagggc gataaagttt ctcaactgtc
    32341 agaatatcag tcttgatttg gacatttgac aaggctttat tgatcatggt cgcgacggta
    32401 aaggtatcat gcttacttct tagaacagga atcccttttt gattggccag tttaagcaca
    32461 tcatcatgaa cctgaaatcc ccctgtaacc agaactgcat tttcattttc caaggctagc
    32521 aactgaatac gggttcggtc tccgacaatc aagagccccc catcatgaag gtaagacaag
    32581 atattttgtt cagtcatggc accaattgaa aacttactaa attctctctc taaaccttct
    32641 tgcccagcca gaacctcaga agaagtcact tctgcaattt cagcaaacgt taatctctct
    32701 atagcaactt tctgggattt aacacgaatt gttccacttc taggacgggt ctccacaatt
    32761 ccacggtttt cagcttcttt aatagcccga taggctgttc catcactaac tcctagatga
    32821 ttcgaaatgc tacgaacact gaccctttta cctactggta attcctccaa atagcttaga
    32881 atttcctgat gcttactcat tgaactctcc ttttacatac cgaaattcaa gataatcccg
    32941 catttttctt gtgtaacgat cacttccctt aaactgacgg aacaaactaa atccagactt
    33001 aagagcaact ctttggctag cttcattttc aaggtgggta atgatagata attgttttaa
    33061 gccaaattcc tcaaaagaaa gctgacaaat ttttctaaca acctctgtca taaatccttg
    33121 cgaccaagca tcttttctca aaaaatagcc aagctcagct tcttttttga tttcatctaa
    33181 cttctcaaat ttaatagaac caatcatttg ttgatttttc tggtcacaaa ttgcccacac
    33241 tcccaaaggg gacttcataa agtaattggc cagtgcatat tgactttctt ccagacttgc
    33301 ctgcgttggg aaaataaatt gaagattttc tggatttgaa gctatctcgc ggaagtcctg
    33361 actatcacta aaaaagaaag gacgcaaata caagcgatcc gtttcaaaaa aagaaaacat
    33421 tgctaatttg gtccaaatat tcataaacac ctctacggtt taatcctcaa caagtctaat
    33481 atccgctcct aaattacgta atttttcgat aatatcagaa taaccacgta agataaactc
    33541 gatattggta atttcagttt taccttcagc cataagccca gcaatgacta gtgcagcccc
    33601 agctcttaag tcggtcgctt taatactggc cccacgtaaa tcacgtccac ccgtgtacaa
    33661 aatatgacca tttgttgtcg aaatatccgc atccatcttt gctagttcaa aaacatgatt
    33721 tacacgtttt tcgtaaatcg tatcgacaat tgtaccacga ccattcgctc ttagtaaaag
    33781 aggggtaagc ggttgttgca aatcagttgc aaagcctggg taaggagctg tcttaatatt
    33841 gattgctttc aaattagact gttcctcgac aaaaatgctg tcttcagata cagtcattct
    33901 cactcccatt tcttccaact tagcaataaa cccttccagg tgttcgtaaa gaacattatt
    33961 tatacgaatt cctttaccaa ctgcagcagc taaagatata tatgttccag cttcaatgcg
    34021 gtctggaatc acctgatgac gtgtcccatg taatctttca acaccatcaa taatgatgat
    34081 attagttcct gccccacgga tatgggcacc catattattc aagagagtag ctacatcaat
    34141 aatctcaggt tcacgggctg cattttcaat aatagtacga ccatttgctt taaccgcagc
    34201 aatcatcgta ttaatcgttg ctcccacact aaccgtatcc atgtaaatac ttgcaccatg
    34261 aagtcctgta tctttagcag ataacttcat gttatctccc tcgtagctag cagtggcacc
    34321 catagcttca aacgccttaa ggtgtaagtc aatcggacga ggaccaagat cacatcctcc
    34381 cggtagacca actgtcgctt caccaaaacg gcctaagagg ctcccataaa aatagtaaga
    34441 tgcacgaaga ctgttaattt taccataagg cattggaata ttttgaacac ctcttggatc
    34501 aatctccaag acatcgtcat aacgcttaac agtagctccc attaattcca tgatttcgac
    34561 aagactggct acatccgaaa tatctggaac acaatccaaa gtcaccacat catcagccaa
    34621 tataatagct ggaattaagg ccacaacact atttttagca ccactaatag taatttcacc
    34681 ttgcagtggt aatccaccat tgataacaat ttttctcatt ctaagttttc aatactcttt
    34741 caagatttct aataaggtct tcaaaataaa gtatatcata aatttatcct tttttccatc
    34801 cttttcaatt ttattggata aatcagagtt gacgagttag taactgaatt actaatactc
    34861 aatgaaaatc aaagatcaaa ctaggaaact agccgcaggt tgctcaaaac actgttttga
    34921 ggttgtagat ggaactgacg tagtcagtat cctacacata cggcaaggcg atattgacgt
    34981 gatttgaaga gattttcgaa gagtataatc tttctcgaat cgctattgcc ccttttttat
    35041 cccctaaaac tgagtaggat ctaagactag atctcttatc taagtatcgg aatacggctg
    35101 ttcaactaaa ttttagcaag aacttctccc cttctctcag ttcacagaag cgttttatac
    35161 ataccgtcct atcagacaat ctattttaaa gataaccgtg actcaggatc acttctatct
    35221 gtcgttttct ctttatagtg atagacctca cgggataagt cgtacatctt tcctcgtgta
    35281 tacaagatat aaggacgtta aaaggttaca gtgaaaatag aaaatcttag tacgaattca
    35341 attactctcg tgatttacgc atataggtta cgactacctt tttggacttt agagtttgag
    35401 acccccttat ccgctatata cgccttacta tcacgttcct gttcgtaaag ccacgatttc
    35461 gctatccctt cctctgacga ttcttatttc cagcgtcaga cttaaaacgg tctatcccca
    35521 gaccgtttta atccactacc tcacgatagt cgggcttggg aatcgctatt tgactcgccg
    35581 agaactttga catcagatat actataacaa attgaaataa gaatcaaaca atttaatttt
    35641 gaaattcaaa tcaatttata acaatatagt
//
LOCUS       DAVLHB010000019        33100 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLHB010000019 DAVLHB010000000
VERSION     DAVLHB010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.019"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            554..2707
                     /locus_tag="VXE36_001038"
     CDS             554..2707
                     /locus_tag="VXE36_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0779358.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2720..4069
                     /locus_tag="VXE36_001039"
     CDS             2720..4069
                     /locus_tag="VXE36_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0779359.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQVVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4239..4946
                     /locus_tag="VXE36_001040"
     CDS             4239..4946
                     /locus_tag="VXE36_001040"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0779360.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5003..8728
                     /locus_tag="VXE36_001041"
     CDS             5003..8728
                     /locus_tag="VXE36_001041"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0779361.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8821..10263
                     /locus_tag="VXE36_001042"
     CDS             8821..10263
                     /locus_tag="VXE36_001042"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0779362.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10300..11322
                     /locus_tag="VXE36_001043"
     CDS             10300..11322
                     /locus_tag="VXE36_001043"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0779363.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKTLEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11319..11864
                     /gene="purN"
                     /locus_tag="VXE36_001044"
     CDS             11319..11864
                     /gene="purN"
                     /locus_tag="VXE36_001044"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0779364.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLECAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            11948..12457
                     /locus_tag="VXE36_001045"
     CDS             11948..12457
                     /locus_tag="VXE36_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0779365.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEY
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12482..14029
                     /gene="purH"
                     /locus_tag="VXE36_001046"
     CDS             12482..14029
                     /gene="purH"
                     /locus_tag="VXE36_001046"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0779366.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLGSDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14151..15413
                     /gene="purD"
                     /locus_tag="VXE36_001047"
     CDS             14151..15413
                     /gene="purD"
                     /locus_tag="VXE36_001047"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0779367.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAADTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            15815..16303
                     /gene="purE"
                     /locus_tag="VXE36_001048"
     CDS             15815..16303
                     /gene="purE"
                     /locus_tag="VXE36_001048"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0779368.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16290..17381
                     /gene="purK"
                     /locus_tag="VXE36_001049"
     CDS             16290..17381
                     /gene="purK"
                     /locus_tag="VXE36_001049"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0779369.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17391..17618
                     /locus_tag="VXE36_001050"
     CDS             17391..17618
                     /locus_tag="VXE36_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0779370.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17681..18979
                     /gene="purB"
                     /locus_tag="VXE36_001051"
     CDS             17681..18979
                     /gene="purB"
                     /locus_tag="VXE36_001051"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0779371.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19034..22972)
                     /gene="strH"
                     /locus_tag="VXE36_001052"
     CDS             complement(19034..22972)
                     /gene="strH"
                     /locus_tag="VXE36_001052"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0779372.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEKTPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYDSDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGSPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23286..24002)
                     /locus_tag="VXE36_001053"
     CDS             complement(23286..24002)
                     /locus_tag="VXE36_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0779373.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24349..26136
                     /locus_tag="VXE36_001054"
     CDS             24349..26136
                     /locus_tag="VXE36_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0779374.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26133..26609
                     /locus_tag="VXE36_001055"
     CDS             26133..26609
                     /locus_tag="VXE36_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0779375.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26637..27542
                     /locus_tag="VXE36_001056"
     CDS             26637..27542
                     /locus_tag="VXE36_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0779376.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVVVAAPSTPSESGEIEDDEF"
     gene            27529..28344
                     /locus_tag="VXE36_001057"
     CDS             27529..28344
                     /locus_tag="VXE36_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0779377.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28351..28755
                     /locus_tag="VXE36_001058"
     CDS             28351..28755
                     /locus_tag="VXE36_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0779378.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29050..30216
                     /locus_tag="VXE36_001059"
     CDS             29050..30216
                     /locus_tag="VXE36_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0779379.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30332..31369
                     /locus_tag="VXE36_001060"
     CDS             30332..31369
                     /locus_tag="VXE36_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0779380.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31576..32430
                     /locus_tag="VXE36_001061"
     CDS             31576..32430
                     /locus_tag="VXE36_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0779381.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            32580..32837
                     /locus_tag="VXE36_001062"
     CDS             32580..32837
                     /locus_tag="VXE36_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0779382.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT         9128 a         6453 c         7750 g         9769 t
ORIGIN      
        1 ttactttgtt atttatttaa tccatcggat ataaagtttg cctatttcag cgtattgaca
       61 gtattactaa ttgggataac aaattatgcg agatttaaaa atttaagatt gacagtagtg
      121 ttttctgtac catttttatt taatgctata atgtctatta taaatagttt ttagaaatac
      181 taaaattttt ttctttactt aataatgata tgaaatcatt tcggttttgt taacttgtaa
      241 ttcttatatt ttctaggtag aacgtttgtt ctgcctattt ttttatccaa aaagtgcagt
      301 tgggagggag ataggctcat ttgggaagga agtccagttt ttgtttagtg attggggtaa
      361 gatagttgtt atcagatgag tttatactct tcgaaaatca aattcaaacc acgtcaacgt
      421 cgccttgccg tatatatgtg actgacttcg tcagtcctat ctacaacctc aaaacagtgt
      481 tttgagcagc ctgcggctag tttcctagtt tgctctttga ttttcattga gtattaggga
      541 aaaggagatg aatatgaaat ttgggaaacg tcactatcgt ccgcaagtgg atcagatgga
      601 ctgcggtgta gcttcattag ccatggtttt tggctactat ggtagttatt attttttggc
      661 tcacttgcga gaattggcta agacgaccat ggatgggacg acggctttgg gcttggtcaa
      721 ggtggcagag gagattggtt ttgagacgcg agccattaag gcggatatga cgctttttga
      781 cttgccggat ttgacttttc cttttgttgc ccatgtgctt aaggaaggga aattgctcca
      841 ctactatgtg gtgacggggc aggataagga tagcattcat attgccgatc cagatcccgg
      901 ggtgaagttg actaaactgc cacgtgagcg ttttgaggaa gaatggacag gagtgactct
      961 ttttatggca cctagtccag actataagcc tcataaggaa caaaaaaatg gtctgctctc
     1021 ttttatccct atattagtga agcagcgtgg cttgattgcc aatatcgttt tggcaacact
     1081 cttggtaacc gtgattaaca ttgtgggttc ttattatctg cagtctatca ttgataccta
     1141 tgtgccagat cagatgcgtt cgacactagg gattatttct attgggctag tcatcgtcta
     1201 catcctccag caaatcttgt cttacgctca ggagtatctc ttgcttgttt tggggcaacg
     1261 cttgtcgatt gacgtgattt tgtcctatat caagcatgtt tttcacctcc ctatgtcctt
     1321 ctttgcgaca cgcaggacag gggagatcgt gtctcgtttt acagatgcta acagtatcat
     1381 cgatgcgctg gcttcgacca tcctttcgat tttcctagat gtgtcaacgg ttgtcattat
     1441 ttcccttgtt ctattttcac aaaataccaa tctctttttc atgactttat tggcgcttcc
     1501 tatctacaca gtgattatct ttgcctttat gaagccgttt gaaaagatga atcgggatac
     1561 catggaagcc aatgcggttc tgtcttcttc tatcattgag gacatcaacg gtattgagac
     1621 tatcaagtcc ttgaccagtg aaagtcagcg ttaccaaaaa attgacaagg aatttgtgga
     1681 ttatctgaag aaatccttta cctatagtcg agcagagagt cagcaaaagg ctctgaaaaa
     1741 ggttgcccat ctcttgctta atgtcggcat tctctggatg ggggctgttc tggtcatgga
     1801 tggcaagatg agtttggggc agttgattac ctataatacc ttgctggttt actttaccaa
     1861 tcctttggaa aatatcatca atctgcaaac caagcttcag acagcgcagg ttgccaataa
     1921 ccgtctaaat gaagtgtatc tagtagcttc tgagtttgag gagaagaaaa cagttgagga
     1981 tttgagcttg atgaagggag atatgacctt caagcaggtt cattacaagt atggctatgg
     2041 tcgagacgtc ttgtcggata tcaatttaac cgttccccaa gggtctaagg tggcttttgt
     2101 ggggatttca gggtcaggta agacgacttt ggccaagatg atggttaatt tttacgaccc
     2161 aagtcaaggg gagattagtc tgggtggtgt caatctcaat cagattgata aaaaagccct
     2221 gcgccagtac atcaactatc tgcctcaaca gccctatgtc tttaacggaa cgattttgga
     2281 gaatcttctt ttgggagcca aggaggggac gacacaggaa gatatcttac gggcggtcga
     2341 attggcagag attcgagagg atatcgagcg catgccactg aattatcaga cagaattgac
     2401 ttcggatggg gcagggattt caggtggtca acgtcagaga atcgctttgg cgcgtgctct
     2461 cttgacagat gcgccggtct tgattttgga tgaggcgact agcagtttgg atattttgac
     2521 agagaagcgg attgtcgata atctcattgc tttggacaag accttgattt tcattgctca
     2581 ccgcttgact attgctgagc ggacagagaa ggtggttgtc ttggatcagg gcaagattgt
     2641 cgaagaagga aagcatgctg atttgcttgc acagggaggc ttttacgccc atttggtcaa
     2701 tagctagaaa gaggagagga tgaaaccaga atttttagaa agtgcggagt tttataatcg
     2761 tcgttaccat aatttttcca gtagtgtgat tgtacccatg gcccttctgc tcgtgttttt
     2821 acttggcttt gcaactgttg cagagaagga gatgagtttg tccactagag ctactgtcga
     2881 acccagtcgt atccttgcaa atatccagtc aactagcaac aatcgtattc ttgtcaatca
     2941 tttggaagaa aataagctgg ttaagaaggg ggatcttttg gttcaatacc aagaaggggc
     3001 agagggtgtc caagcggagt cctatgccag tcagttggac atgctaaagg atcaaaaaaa
     3061 gcaattggag tatctgcaaa agagcctgca agaaggggag aaccactttc cagaggagga
     3121 taagtttggc taccaagcca cctttcgcga ctacatcagt caagcaggca gtcttagggc
     3181 tagtacatcg caacaaaatg agaccatcgc gtcccagaat gcagcagcta gccaaaccca
     3241 agccgaaatc ggcaacctca tcagtcaaac agaggctaaa attcgcgatt accagacagc
     3301 taagtcagct attgaaacag gtgcttcctt ggccggtcag aatctagcct actcttttta
     3361 tcagtcctac aagtctcagg gcgaggaaaa tccccaaact aaggttcagg tagttgcaca
     3421 ggttgaagca cagatttctc agttagaatc tagtcttgct acttaccgtg tccagtatgc
     3481 aggttcaggt acccagcaag cctatgcgtc agggttaagc agtcaattgg aatcccttaa
     3541 atcccaacac ttggcaaagg ttggtcagga attgaccctt ctagcccaga aaatcttgga
     3601 ggcagagtca ggtaagaagg tacagggaaa tcttttagac aaggggaaaa ttacggcgag
     3661 tgaggatggg gtgcttcatc ttaatcctga gaccagtgat tctagcatgg ttgcagaagg
     3721 tgccctacta gcccaacttt atccatcttt ggaaagagaa ggtaaagcca aactcacagc
     3781 ttatctaagt tcaaaagatg tagcaagaat caaggtcggt gattctgttc gctatactac
     3841 gactcatgat gccgggaatc aacttttcct agattctact attacaagta ttgatgcgac
     3901 agctactaag actgagaaag ggaatttctt taaaatcgag gcggagacta atctaacttc
     3961 ggagcaggct gaaaaactta ggtacggggt ggaaggccgc ttgcagatga ttacgggcaa
     4021 gaaaagttat ctacgttatt atttggatca atttttgaac aaagagtaat gttcgtgttt
     4081 ttagagttaa ataattttta aactgtgaga aagattcttc ttgcagtttt ttctttacaa
     4141 tttttggaaa acatctgcta tttattcggt taaattcttg tattttttgg ttttttgtgg
     4201 taaaatgtgc tcaagtaata cgaaaggcga actttaaaat gtcaaaacaa ttgatctatt
     4261 cgggaaaagc taaagatatc tatacaactg aggatgaaaa tcttattatt tcaacttaca
     4321 aggaccaggc gactgctttc aacggtgtca agaaggagca gattgcaggt aagggagtct
     4381 tgaataatca gatttcatct tttatttttg agaaattaaa tgcggctggt gtggcgactc
     4441 actttgtgga gaaactttca gacacggaac aactcaataa aaaggttaag attattcctt
     4501 tggaagtcgt gctccgcaat tatactgctg gttccttttc aaaacgtttt ggtgtggatg
     4561 agggaatcgc cttggagact ccgattgtcg aattttacta caaaaatgat gatttggatg
     4621 atccatttat caatgatgag catgtgaaat tcctacagat tgcggatgac cagcagattg
     4681 cctacttgaa ggaagaaacg cgtcgtatca atgaactatt gaaagtctgg tttgctgaga
     4741 ttgggcttaa attgattgac tttaagctag agttcggttt tgacaaggat ggcaagatta
     4801 tcttggcaga cgaattttca ccagataact gccgcttgtg ggatgctgat ggcaaccaca
     4861 tggataagga tgttttccgt agaggattgg gagaactaac cgacgtttat gagattgttt
     4921 gggaaaagtt gcagggttta aaataacaac ctcaaggctg tttgggaata ttgcaagagc
     4981 tgaaataaag gaataagaat tgatggataa acgtattttt gttgaaaaaa aggctgattt
     5041 tcaggtcaag tcagagagtt tggttagaga gctccagcac aacttgggac tgtcaagctt
     5101 gaaaagtatt cgtattgtgc aagtatatga tgtatttgac ttggttgagg acttgtttgc
     5161 acctgcagag aagcacattt tctctgagca ggtaaccgac catgttttag atgaagtatc
     5221 tgtgcaggcg gatcttgcta actatgcttt ctttgccatt gaaagtctac cagggcagtt
     5281 tgaccagcgt gcagcttcgt cacaggaagc cttgcttttg ttgggaagtt cgagtgacgt
     5341 gacagtcaac acagcccaac tttacttggt gaataaagat attgatgcga ctgagttgga
     5401 agctgtcaaa aactacctgc tcaatccagt tgattctcgt ttcaaggata tcacgacagg
     5461 gattgccaag caggagtttt cagagtcaga caagaccatt ccaaaattga ctttctttga
     5521 aagctataca gcagaagact ttgctcgcta caaggccgag caagggatgg ccatggaagt
     5581 ggatgatttg ctctttatcc aagactactt taagtcaatc gggcgcgtgc caactgagac
     5641 tgaactcaag gttttggaca cttactggtc tgaccactgc cgtcatacga cttttgagac
     5701 agagttgaaa cacatcgact tttcagcttc taaatttcaa aagcaattgc agtcaaccta
     5761 tgacaagtat attgccatgc gcgaggagtt aggtcggtct gaaaaaccac aaaccttgat
     5821 ggatatggcg actattttcg gtcgttatga gcgtgctaat ggacgattgg atgatatgga
     5881 agtctctgac gaaatcaatg cctgctcagt tgaaattgaa gtggatgttg atggtgtcaa
     5941 ggaaccttgg ctcctcatgt ttaaaaatga aacccacaac catccaacag aaattgagcc
     6001 atttggtgga gcggctacct gtatcggtgg agctattcgt gatccgttgt caggccgttc
     6061 ctatgtttac caagccatgc gtatttcagg tgctggtgat attacagcac cgatttcgga
     6121 aactcgtgct gggaaattgc cacaacaagt catttctaaa acagcagctc atggttattc
     6181 ttcatatggt aaccagattg ggcttgccac aacctacgtt cgtgaatact tccacccagg
     6241 ctttgtagct aaacgtatgg aacttggtgc cgttgttggt gcggctccca agggcaatgt
     6301 tgtccgtgaa aaacctgaag caggtgatgt gatcatcctt ctcggaggca aaacaggtcg
     6361 tgatggtgtc ggtggtgcga cgggctcttc taaggttcaa acagttgagt ctgtagagac
     6421 tgctggtgct gaggttcaaa aaggaaatgc catcgaagaa cgcaagattc agcgcctctt
     6481 ccgtaatggc aatgtcactc gtctgatcaa gaagtccaat gactttgggg caggcggcgt
     6541 ctgtgtggct atcggtgaat tggcagacgg tcttgaaatc gacctcaaca aggtgcctct
     6601 taaataccag ggcttgaatg gtacagaaat tgccatctct gaatcacaag aacggatggc
     6661 ggtcgtggtt cgtcctgaag atgtggatgc cttcgttgcc gaatgtaaca aagaaaatat
     6721 tgatgctgtt gtggtggcga cagtaactga aaaaccaaat cttgtcatgc actggaatgg
     6781 tgagacaatc gttgacttgg agcgtcgttt ccttgacacc aatggtgtgc gcgtggttgt
     6841 cgatgccaaa gttgtggaca aggatgtcaa actcccagaa gagcgtcaaa catctgctga
     6901 aacactggaa tcagataccc ttacggttct atctgacctc aaccatgcaa gtcaaaaagg
     6961 attacagact atctttgact gctctgttgg acgctcaacg gttaatcacc cacttggtgg
     7021 tcgttaccaa ctcacaccaa ctgaggcatc tgtgcagaaa ttgccagttc aacacggtgt
     7081 gactcatact gcgtcggtca ttgctcaagg tttcaaccca tatgtagctg aatggtctcc
     7141 ataccacggt gctgcttatg cggttatcga agcaactgct cgtttggtgg ctgctggtgc
     7201 caactggtcc aaggctcgtt tctcttacca agagtatttc gagcgtatgg ataaacaagc
     7261 agagcgtttc ggtcagccag tagctgctct tctaggttct attgaagcac aaattcagct
     7321 tggcttgcca tctatcggtg gtaaggactc catgtctggt acctttgaag aattgaccgt
     7381 tccgccaacc ttggttgcct ttggggtgac gacggcagat agccgtaagg tgctctctcc
     7441 agaatttaaa gctgttgggg aaaatatcta ctacatccca ggtcaagccc tctctgcaga
     7501 gattgatttt gacttgatta agaaaaattt tgctcagttt gaagcaagcc aagctgacca
     7561 taaagtgaca tctgcatcag ctgtcaaata cggtggtgta gttgaaagtt tggctcttgc
     7621 tacctttgga aactatattg gtgcagaggt gaccttgcct gaacttaaaa cagctttgac
     7681 agctcaatta ggcggctttg tcttcacatc tcctgaagaa attgctggag tagagaagat
     7741 tggacaaacg aaagcagact ttacactgac tgtcaacggt gtgaagctag atggacacaa
     7801 gcttgacagt gcatttcaag ggacattgga agaagtttac ccaacagaat ttacccaagc
     7861 gaaagaacta gaagaagtac cagctgtggc atcagatgtt gtgattaaag ccaaagaaaa
     7921 ggttgaaaaa cctgtggttt acatcccagt ctttccagga accaactcag aatatgattc
     7981 agctaaggcc ttcgaaaaag aaggtgcaga ggtcaatttg gtgccattcg tgaccttgaa
     8041 tgaagaagct attgtcaagt cagttgaaac tatggttgac aatatcgaca agactaatat
     8101 tctcttcttt gccggtggat tctcggctgc ggatgaacca gatggttcag ctaagtttat
     8161 cgtcaatatc ctgcttaatg aaaaagtgcg tgtggctatt gatagcttta tcgcccgtgg
     8221 tggcttgatt atcggtattt gtaatggatt ccaagcctta gtcaaatcgg gtctcctacc
     8281 atacggaaac tttgaagatg ctaacagtac tagtccaacc ctcttctaca atgatgccaa
     8341 ccaacacgtg gccaagatgg tggaaactcg cattgccaat accaactcac catggttggc
     8401 tggtgtgcaa gtgggcgata tccacgctat tcctgtttcg cacggtgaag ggaagtttgt
     8461 cgtgacggct gaggaatttg cagagctccg tgacaatgga caaattttca gccaatacgt
     8521 tgactttaac ggtaaaccaa gtatggattc taagtacaat ccgaatggtt ctgtccatgc
     8581 catcgaagga attaccagca agaatggtca aatcatcggt aagatgggcc actcagaacg
     8641 ttatgaggat ggtcttttcc aaaatatccc aggcaataaa gaccaacacc tgttcgcatc
     8701 agcggttaaa catttcactg gaaaataaga cttacagatt ttctaataga tagtatcagt
     8761 aatgtaaaag tcatgtaaat ctagctcttg atgattacaa atgaaaatta ggtataaaaa
     8821 atgacatacg aagtaaaatc tcttaatgaa gaatgtggtg ttttcggtat ttggggacat
     8881 ccagatgctg ctaagttgac ctattttgga ctccacagtc ttcaacaccg tggtcaggag
     8941 ggggcaggaa tcctctccaa cgatcaagga caactgaagc gccatcgtga catggggctt
     9001 ttatcagaag ttttcagaaa tccagctaat ttggataaat tgacaggagc tggtgcgatt
     9061 gggcatgtgc gttatgcgac tgctggcgaa gcttctgtag ataacatcca gcccttcctc
     9121 ttccgttttc acgatatgca gtttggcttg gctcataatg gaaatctgac caatgcagcc
     9181 tctctcaaga aagaactgga acaaagagga gcaattttca gcgcgacttc ggactctgaa
     9241 atcttggctc acctcattcg tcgcagtcat aatcctagcc tgatgggcaa aatcaaggaa
     9301 gcgctcagcc ttgtcaaagg tggttttgcc tatatcttgc tgtttgagga caagttgatt
     9361 gcggctcttg accctaatgg ctttcgtccg ctttctatcg ggaaaatggc caacggagcg
     9421 gtggttgttt cctctgaaac ctgtgctttt gaggtcattg gtgccgagtg gattcgtgat
     9481 ttgaagccag gtgagattgt gatcattgat gacgagggca ttcagtatga cagctataca
     9541 gatgataccc agttggcgat ttgttctatg gagtatatct actttgctcg ccctgattct
     9601 aatatccacg gtgtcaatgt ccatacggca cgtaagagaa tgggagcgca attggcgcga
     9661 gaatttaagc atgaggcaga tattgtagtt ggtgtgccca attcttccct aagcgcggct
     9721 atgggatttg cggaagaatc aggcttacca aatgaaatgg gtctgatcaa aaaccaatac
     9781 acccagcgaa cttttatcca accgactcaa gaattgcggg agcaaggagt gcggatgaaa
     9841 ctgtctgctg tttcgggtgt tgtcaaaggc aaacgtgtgg tcatggtgga tgattccatt
     9901 gtacgtggaa caacctctcg tcgtatcgtt cagctcttga aagaagcggg tgcgactgag
     9961 gttcacgttg ccattggaag tcctgcacta gcgtatccat gtttctacgg gattgatatc
    10021 cagacccgtc aggagctgat tgcagccaat catacggtcg aagaaactcg ccaaatcatt
    10081 ggtgcggaca gtctgactta tctttcaatt gatagcttga ttgagtcgat tggtatcgaa
    10141 acagatgcgc cgaacggtgg tctctgtgtc gcttactttg acggtgacta cccaacgcct
    10201 ctctatgact acgaagaaga ctatcgtaga agtttggaag aaaagaccag tttttacaag
    10261 taggcgacag attctccatt aaagaaaagg aaaaaacaaa tgacaaataa aaatgcatat
    10321 gcccagtcgg gtgtggatgt tgaagcgggt tatgaagttg ttgaacggat taaaaagcac
    10381 gtggcccgta cggagcgtgc aggtgtcatg ggagctcttg gtggctttgg tggtatgttt
    10441 gacctttcca agactggggt taaagaaccc gtcttgattt cagggactga cggtgtcgga
    10501 accaagctca tgttggctat caagtacgac aagcacgata ccatcgggca ggactgtgtg
    10561 gccatgtgtg tcaacgacat cattgctgca ggtgcggaac ccctctattt tctcgactac
    10621 gtagcgacag ggaagaatga accagctaag ctagaacaag tggttgctgg tgtggcagaa
    10681 ggttgtgtgc aggctggtgc tgccctcatc ggtggggaaa cggctgaaat gccgggcatg
    10741 tacggcgaag acgactatga cttggctggt tttgcggtcg gtgtggctga aaaatctcaa
    10801 atcattgacg gttcaaaggt ggtagaggga gatgttcttc tcggacttgc ttcaagtggg
    10861 attcactcaa atggttactc tttggttcgt cgtgtctttg cggattacac aggtgaggaa
    10921 gtcctaccag aattggaagg caagaaactt aaggaagttc tacttgagcc gactcgtatc
    10981 tatgtcaagg ctgtcttgcc gctcatcaaa gaagagttgg tcaacggcat tgcccacatc
    11041 acaggtggtg gctttatcga aaatgtccct cgtatgtttg cagatgacct agctgctgaa
    11101 attgatgaaa gtaaagttcc agtgcttcca attttcaaaa cccttgaaaa atacggtcag
    11161 attaaacacg aagaaatgtt tgaaatcttc aatatgggtg tgggactcat gttggcggtc
    11221 agccctgaaa atgtagagcg tgtaaaagaa ttgttggatg aagcagtcta tgaaattggt
    11281 cgcatcgtca agaaagaaaa cgaaagtgtc attatcaaat gaaaaaaata gcggtttttg
    11341 cctctggtaa tggctcaaat tttcaggtga ttgccgaaga atttccagtg gagtttgtct
    11401 tttcagacca tcgtgatgcc tatgtgcttg agtgtgcaaa gcagctcggc gttctgtcct
    11461 atgcttttga actcaaggag tttgagagca aggcagacta cgaagcagcc cttgtcgaac
    11521 tcttggaaga acaccagatt gacttggttt gcctagcagg ctacatgaaa atcgttggac
    11581 caaccttatt gtcggcttat gaaggtcgga ttgtcaacat tcatccagcc tacttgccag
    11641 aatttccagg agctcatggg attgaggatg cttggaatgc tggcgtgggt cagtctggtg
    11701 tgaccattca ctgggtggat tcgggtgtgg atacaggcca ggtcatcaaa caggttcgtg
    11761 tgccacgact agctgatgat accattgaca gatttgaagc tcgcatccat gaagcagagt
    11821 acaggttgta tccggaagta gtgaaggctc tatttacaga ttgacttttt gatgattcat
    11881 atgatatctt tgattttaaa ttggagtcag tgtttgttga agacggcttc aaacggaggt
    11941 atttgtaatg ttagaatcta aaaaaacaac tcgatatgta ttttatgtct atctgatgtt
    12001 attaacttgg ggaatcttat ttaagtttga aacaaatcct gaatttatag catttttctt
    12061 agctccaagg tatatcaatt ggattccatt ttcagaacca ctaatagtcg atggaaaaat
    12121 tgtttttgct gaaatgttat ttaatctgat tttctttatt ccattaggtg tttgtttccc
    12181 tttgataaaa actaatttat ctagtttaag aatagtcggg acaggtttct tgattagttt
    12241 attgtttgag tacttacagt atattttagc aataggtata acagatataa cggatttgac
    12301 tttaaatacg ctaggtgtct gtgtaggctt actgatttat caaattttta taagagtgtt
    12361 caaatcacag actagaaaat ggatcaatat cttaggtatg cttagccttg gttttgctta
    12421 tcttgtttta ctgttactgc atttaattgg tgtttaacta atgattaaaa aggagaatat
    12481 aatgactaaa cgcgtcttaa tcagcgtctc agacaaagcg ggcattgttg aatttgccca
    12541 agaactcaaa aaacttggtt gggagattat ctcaacaggt ggaactaagg ttgcccttga
    12601 taatgctggg gtggatacca ttgctatcga tgatgtaact ggtttcccag aaatgatgga
    12661 cggtcgtgtg aagaccctcc acccaaatat ccacggaggg cttctcgctc gtcgtgactt
    12721 ggatagccac ttggaagcgg ctaaggacaa caagattgag ctcattgacc ttgtggtggt
    12781 caacctttac ccatttaagg aaactatcct taaaccagat gtgacttatg ctgatgcagt
    12841 tgaaaatatc gatattggtg ggccgtctat gcttcgttca gcagcgaaaa atcatgccag
    12901 tgttacagtt gtggtagatc ctgctgacta cgctgtggtt ttggacgaat tggcagcaaa
    12961 cggcgaaacc tcttatgaaa ctcgccaacg tttagcagcc aaagtatttc gtcacacagc
    13021 ggcttatgac gccttgattg cagaatactt cacagctcaa gtgggtgaaa gcaagcctga
    13081 aaaactcact ttgacttatg acctcaagca accaatgcgt tacggtgaga atcctcaaca
    13141 agacgcggac ttttaccaga aagctttgcc tacagattac tctattgctt cagccaaaca
    13201 gctcaacggg aaagaattgt catttaataa tatccgtgat gcagatgctg ctatccgtat
    13261 catccgtgac ttcaaagata gtccaaccgt tgtggctctc aaacacatga atccatgtgg
    13321 aattggtcaa gctgatgaca tcgagactgc ttgggactac gcttatgagt ctgacccagt
    13381 atctatcttt ggtgggattg tcgtcctcaa ccgtgaggtg gatgctgcga cagctgagaa
    13441 gatgcacggc gttttcctcg aaatcatcat tgcaccaagc tatacggatg aagcgctagc
    13501 cattttgatc aataaaaaga aaaacttgcg tatccttgcc ttgccattta atgctcaaga
    13561 ggctagcgaa gtggaagcag aatacacagg tgtagtcggt ggacttctcg tgcaaaatca
    13621 agacgtggtc aaggaaagcc cagctgactg gcaagtggtg accaaacgtc agccaactga
    13681 gacagaagcg actgctcttg agttcgcttg gaaggctatc aagtacgtca aatcaaatgg
    13741 tattatcgtg accaacgacc acatgacact tggtgttggt ccaggtcaaa ccaaccgtgt
    13801 ggcttctgtt cgccttgcca ttgaccaagc caaagatcgt ctgaacgggg cggtccttgg
    13861 ttcagatgcc ttcttcccat ttgcggataa cgtggaagaa atcgccaaag caggaattaa
    13921 ggccatcatc cagcccggtg gctctgtccg tgaccaagaa tccatcgaag cagcggataa
    13981 atacggcttg actatggtct ttacaggtgt gagacatttt agacattaag aagataaaag
    14041 ggaagaaaac agtttctttc cttttttggc ttaaaatgct aactgaaaca agattaaaac
    14101 gaactttttt gatataatgt tggtaaataa ttcgcaaaag aggttgagga atgaaactgc
    14161 ttgttgtcgg ttctggtggt cgtgagcatg cgattgctaa aaagttactt gaatcaaaag
    14221 acgtggaaaa agtctttgta gctcctggga atgacggtat gactctggat ggtctggaat
    14281 tggtaaatat atctatttcc gaacattata aattgattga cttcgcaaag gccaacgata
    14341 ttgcttggac ctttatcggt ccagatgacg cccttgcggc tggtatcgtg gatgatttcc
    14401 atgcagctgg tctcaaagcc tttggtccga caagattggc agcggagctg gagtggtcca
    14461 aggatttcgc caaggaaatc atggtcaaat atggtgtttc gacagcagcc tatggcacat
    14521 tttcagattt cgaggaagca aaggcctata tcgaaaagca tggtgcgcct atcgtagtca
    14581 aggcggatgg cttggcgctt gggaagggtg tcgtcgttgc tgagacggtt gagcaagcgg
    14641 tcgaagccgc tcatgagatg cttttggaca ataaatttgg tgactcaggt gcgcgcgtgg
    14701 ttattgagga attccttgaa ggagaggaat tttcactctt tgcctttgtc aatggtgata
    14761 agttctacat catgccaacg gctcaggacc acaaacgtgc ctacgatggc gacaaagggc
    14821 ctaacacggg tggtatgggt gcctatgcgc cagttccaca cttaccacag agtgtagttg
    14881 atacagcggc tgacaccatt gtcaagccag ttctagaagg gatgattaaa gaaggtcgcc
    14941 cttatctggg agttctttac gcagggctta tcctgacagc tgatggaccg aaagtcattg
    15001 agttcaacgc tcggttcgga gatccagaaa ctcagattat cttgcctcgc ttgacctctg
    15061 actttgctca aaatatcaca gatatcctgg atagcaagga gccaaatatc atgtggacgg
    15121 acaagggtgt gactctgggt gtggttgtcg catccaaggg ctacccgcta gactatgaaa
    15181 ggggcgttga gttgccagcc aagacagaag gcgatgtcat cacctactat gcaggggcta
    15241 agtttgcgga aaatagcaga gcactgctct caaacggcgg acgagtttat atgctcgtta
    15301 ccacagcaga taccgtcaaa gaagcccaag ccagcatcta ccaagaacta taccaacaaa
    15361 aaatagaagg actcttctac cgaacagata tcggaagcaa ggcaattaag taaagatata
    15421 agaataacgc gccgtagtcg ccaaacacga taatggtcgt cgtggtgaaa agaccagaac
    15481 agtgaatgtt ctggtcaggg gaaacttgga gaccttaggc tcaaagttta ggaatgaaac
    15541 cgaaggtttg cttccgcctc catcacctaa gaccattatc aaaaagaaaa ataaaaattc
    15601 acaaaatacg ttaatgatcg tatggtttgc gagcgttagc gagctaatat agaacaatca
    15661 ccgccgttgt gaaagaacga ttggatgata atccaatcgt tcagggaaat tggaagacct
    15721 tgggtttcca atttaggcat gagacacctt tggtggctgc tgccgtccct cacaagctaa
    15781 ggtgattgtt gaaaaagagg aaaaaggaga agaaatgaaa ccagtaattt ccatcatcat
    15841 gggctcaaaa tccgactggg caaccatgca aaaaacagca gaagttctag accgcttcgg
    15901 tgtagcctac gaaaagaaag ttgtttccgc acaccgtaca ccagacctca tgttcaaaca
    15961 tgcagaagaa gcatatagcc gtggtattaa ggtcatcatc gcaggtgctg gaggcgcagc
    16021 ccacttgcca ggaatggtag ctgccaaaac aacccttcct gtcatagggg tacctgtcaa
    16081 gtctcgtgct cttagtggag tggattcact ctattctatc gttcagatgc cgggtggggt
    16141 gcctgttgcg accatggcta tcggtgaagc tggagcgact aacgcagctc tctttgccct
    16201 ccgtctcctc tctgtagaag ataagtccat tgcggatgca cttgccaact ttgctgaaga
    16261 acaaggaaaa atcgcagagg agtcgtcaaa tgagctcatc taaaacaatc ggaattatcg
    16321 gtggcggtca actgggtcag atgatggcca tttctgctat ctacatgggc cacaaggtta
    16381 tcgcgctgga tcctgcggcg gattgcccgg tctctcgtgt ggcggaaatc attgtggcac
    16441 cttataacga tgtagacgcc ctccgtcagt tggcagaccg ttgcgatgtc ctcacttacg
    16501 agtttgaaaa tgtcgacgct gacggtttgg atgccgttat caaggatgga caactccctc
    16561 aagggacaga cctgctccgc atttcgcaaa atcgtatttt tgaaaaggac tttttgtcaa
    16621 acaaggctca agtcactgtg gcaccctaca aggtcgtgac ttctagccta gacttggcag
    16681 atatcgactt gtcgaaaaac tatgtcctca agactgcgac tggtggctac gatggtcatg
    16741 gacaaaaggt tattcgttca gaagtagact tggaagcagc ctatgcgcta gcagaatcag
    16801 cagactgcgt cttggaagaa tttgtcaact ttgcccttga gatttctgtc atcgtgtcag
    16861 gaaatggcaa ggaggtgacg tttttcccag ttcaggaaaa tatccaccgc aacaatatcc
    16921 tgtctaagac catcgtacca gcccgcattt ctgaaagtct agtagacaag gctaaagcta
    16981 tggcagtgcg aatcgcagaa caactcaact tgtctggaac tctctgtgtg gaaatgtttg
    17041 cgactgatga tgacgttatt gtcaatgaaa tcgccccacg accacataac tctgggcact
    17101 attctattga agcctgtgat ttctctcagt ttgacaccca tattctcggt gttctcggag
    17161 caccattacc agtcatcaaa ctccatgcgc cagccgttat gctcaatgtc ctaggtcaac
    17221 acgtcgaggc tgctgaaaag tatgtcgcag aaaatccaag cgcccacctc cacatgtatg
    17281 gtaaaataga agcaaagcat aatcgtaaga tgggacatgt gaccttgttt agtgatgtac
    17341 cggatagtgt ggatgagctt ggggaaggga ttgattttta ggacaagtct atgatacaaa
    17401 ttatcgttaa tacatttatt gaaaaggata agactggagc agttgttgaa gtgttgtatg
    17461 ccagtgctga ccaagataag gtacaagcta aatatgaaga actagctgca caataccccg
    17521 aaaattattt agctatctat gatgtaccgc tggatacgga tttgaataca ctagatcatt
    17581 acccgtctgt gtttattgaa aaagaggagt ttgagtagaa atcttggttt acctagatag
    17641 cttattccca acagcttaag aagaaaggaa aaattaacac atgatcaacc gttactctcg
    17701 ccctgagatg gcgaatattt ggagtgaaga aaataaatac cgtgcttggc ttgaggtgga
    17761 aatcctctct gacgaggcat gggctgagtt gggggaaatc cctaaggaag atgtggcttt
    17821 gattcgcaag aaggcggact ttgacatcga ccgtattttg gaaattgagc aggagacgcg
    17881 ccacgatgtg gtggctttca cgcgtgcggt ttctgagact cttggtgaag agcgcaagtg
    17941 ggttcactat gggttaactt ctaccgacgt ggtggatact gcttatggtt acctctacaa
    18001 gcaggccaac gacatcatcc gtcgtgacct tgaaaacttc actaatatca tcgctgacaa
    18061 ggccaaggag cacaagttca ccatcatgat ggggcgtact catggtgtgc acgctgagcc
    18121 gacaaccttt ggtcttaaat tggcaacttg gtacagcgaa atgaaacgca atatcgagcg
    18181 tttcgagcat gcagctgctg gtgtagaagc tggtaagatt tctggtgcgg ttgggaactt
    18241 tgccaatatc ccaccatttg tagaggagta tgtctgcgat aaacttggca tccgtgccca
    18301 agaaatctct acacaagtcc ttcctcgtga ccttcacgct gagtactttg cggttcttgc
    18361 cagcattgcg acttcaatcg aacgtatggc gactgagatt cgtggtctac aaaaatctga
    18421 gcaacgcgaa gtagaagagt tctttgctaa agggcaaaaa gggtcttcag caatgcctca
    18481 caaacgcaac ccaatcggtt ctgaaaatat gactggtctg gcgcgtgtca ttcgtggtca
    18541 catgattacg gcttatgaaa acgtcgctct ctggcacgaa cgcgatattt ctcactcatc
    18601 agctgagcgt atcatcacac cagatacgac cattttgatt gactacatgc tcaaccgttt
    18661 tggaaatatc gtcaagaact tgacagtctt cccagaaaat atgatccgaa acatgaactc
    18721 gacttttggt cttatcttta gccaacgggc tatgttgaca ttgattgaaa aaggcatgac
    18781 ccgtgagcaa gcctatgact tggtgcaacc aaaaacagcc tactcttggg acaaccaagt
    18841 agactttaaa ccacttcttg aggcagattc agaagtaaca tcacgtctca ctcaagaaga
    18901 aatcgatgaa atcttcaacc cagtttatta caccaaacga gtggatgata tctttgaacg
    18961 tcttggacta ggtgattaat taaaaaataa acagcgagct tcaatctcgc tgtttatttt
    19021 ttatcgaaaa gacttagtct tcttttcttt tagtgagtcc ataggctgct agtgtggaca
    19081 tgagtcctgc gactactagt cctgcagaat cgtgagttcc tgtttcagga agttttttct
    19141 ctgttaccac aggagctgga tcttgaggaa gagctttgct ttcctcagca ggagcagttg
    19201 atggagctgg ttggcttggg atttctagtt ttggtttttc ttcagcaata gcggcttgtc
    19261 cgttttcatc gcctacatgt gttaccatag ttccgacttc gactatttga gtaacggctt
    19321 cctgtgctac gacactattt acaagtgttt tcacttcctt accatcggca gaagtgctca
    19381 cagagtagaa gttgctacga tgtccattga cgcccttagt aatgacttgt gtttttcctt
    19441 tgagtaagag tggattttca cgagtcactg tggtaaatgg aatttcttct tcttggatat
    19501 ccagtctagg ttttacctca gtagttggtg caagaccact ttcatcaccc ttgtgagtta
    19561 caggagagcc aacttcaacc acttggttta taacttcttt ggttacctgg ctatcaagga
    19621 ctgtttctgt tgtttttcca ttttcagtga gtacagagat gtaatgagtt cgttcacctt
    19681 tgactcctgc tgtgataata ttttcctgac cagctgggag gttaggattt tctttcttga
    19741 taacttcaaa tggaatttct tcagttcttg tgatgagttc tggtctggtt tcaacattgg
    19801 cagccacttc attttcatct aggcttcctg aatgagttgc agctggtttg aggccttgaa
    19861 gagcggcttt taggttggct acaagtgtgt caagctcagc ttgtttatta cggttgaggt
    19921 tgtaatttag agctgtttta gctgcgtcaa gggcctcaag actttcttta ctatatcctt
    19981 ctaagtttgt aggaatttta gctaattctt cgcggagagc attataatta gcacggaagt
    20041 agtctttgtt gtggtctgca aaggcagtca tgagttcaaa gatttcctct tccttgtact
    20101 cagcgcttgg tctatctgcc cagattgaaa gcatacttcc gactgttgga agatctactt
    20161 caggatattt ggtagaagct agttgattga atggaacttt accagaattt tcaactgctt
    20221 ttgaaagagg gtaagcttca tcttgtttgt gattgcctat aacataatac cagtcaccgt
    20281 tggtattcaa gaatttatag cctttgcttg ctaggtattg aggtgatgcg aggttatatc
    20341 cccaccagcc tttagaccag taagaaatca agacatcttt gtcaaactga acatcgtcct
    20401 tgtcttcata gtagaagcca tcgttgaagg ccattggttg aagccctctt tctttggcca
    20461 tagctgcgag ggtgttggca tattcggcaa atttgccata gagttgatac cacttgaggt
    20521 agtaccagcc ttgggcacta gtcgcatcgt tggcgtattc gtcagtacca aagttgaaaa
    20581 tctttgtttt acctgcaaag aagtccatgt atttaccgat gagggctttt acaaagttca
    20641 tcgcttcttc gtttttcaag tccatagttg tttttgaaac tttatcaaag tgggcttgag
    20701 gatttttaat acctaatttt tccatggcaa ccagcatagc atccatgtga cctggactgt
    20761 taatagctgg gatgagacca atgtccttag atttagcgta ttcaattagc tctgtcactt
    20821 ctgcctgtgt tagtgcagta ccgtttggat cgtcgtagta agctttagtt ccttcgataa
    20881 tagctttttt aacgtcatca ctagcatagg tttttccgtt ggcagtaatg gtcatatcat
    20941 tgagtagaaa gcgaagtccg tcatttccta gaaggagatg gacatcagaa tatccgagct
    21001 cactggcctt gtctacgatg cgtttgagct ggtccagagt aaagtatttg cgtccagcat
    21061 cgattgagat taccttgttt ttggcaagtt tttcaacctc acgtttagct tcttcttctt
    21121 tttgagcttc aggcgtgagg gtcaagttgt tgacagtttc ttgaagttta gcaatggctt
    21181 gatcaatcgt atcttgttgg gcacggctaa ggttgctatc gagagagcga atagcttttt
    21241 cagcttcttt tacggccgcg acgctttctg cagtataacg gttcaggtct tttggtacct
    21301 cgttaagtgc ttgctctgca gattcataat cagctgcgaa gtattcagcg ttggcatttg
    21361 caaaatgacg catgagtttg aagaggtgtg atggtgaata acgtgcagat ggagtgtcag
    21421 cccaagcagc taccatacca ccgatgattg ggatatcagc tccttctgtt tttggtacag
    21481 aagtgattgg tgtgttttta ataccattga gcccctgatc gagattgtac cagccttggc
    21541 catcagcgtt tcgtccaaga acgtagtacc aagcatcatt ggtattaagg atttggtgac
    21601 ctttttcagc tagtagttta gaagaagcga catcgtagcc tccccaacca ccagtccaca
    21661 tagaaacgat gatgtctttg tcaaaactac caaagcttgt gtcgctattg tagtagatac
    21721 cgtcgttaaa ggccattggt ttgagaccgt gcgattttac aatacgagcg aggtcattgg
    21781 cgtaggcaat aaatttttca tagcctttta cagggtagcc ttcgtttgga tagtatttat
    21841 cagcttgaag cacactccaa cctttagcat ctgtcgcatc attggcatat tcatcaagtc
    21901 cgatgttgaa gatttcagtc tttttcgcga aataagcagc atacttgtcg ataagggctt
    21961 ttgtaaaagc gacagcttgt tcgttgtcaa gatcgacagt acgggctgat ttcttcccaa
    22021 aatagctaaa gttagggttt tggattccca attctttcat ggcattgaga atcgcatcca
    22081 tgtgtccagg actatttact gtcggaatga gaccgatacc tttatctttg gcatagttaa
    22141 tcagatctgt catttgactt tctgttaagt gattgccgtt tggatcgttg taataatcat
    22201 ttgtaccttt ttcaatggcg cgtttgacat cgtcactgtc ataggtcttg ccgttagctg
    22261 tgatgctcat atcgtccaac atgaaacgga gtccatcatt tccgactaat aggtgtaaat
    22321 cagtgtagcc ataatgtttc gctttatcga tgatttcctt gagctgttct ggtgagaaat
    22381 atttacgtcc agcatcaata gaaacaattt tctttttcgc tagtttttca tttacagttg
    22441 cagcacgttc ctttcctgcc tctgtttccg gtttgtcagc ctctgctttc gcttcatctt
    22501 ttttagctgg tttatctttg tcagtcttgt ccgtatttga ctctttagaa tcaacctctt
    22561 tcgcttcttc ctttttaggg ctagcttctt ctgccttttt attagcagtt tctttttcag
    22621 cagaagttgg agttaccact tctgctttat cactaggagt tgaactaact tcctcttgtg
    22681 gtttttcttc tgtttttgga agactagcta ccttatcagt agctggagtt tctgtttcta
    22741 cagtttttgg agcttctggt tgaagctctg ctttaggtgt tttctcagtc cgattttcgg
    22801 atgattgagg ggaatcagaa accgtatgga tggtcggttg gttttctgta gtagtaggag
    22861 taactccatc ggctgcaaca gtctgtgctt ggaaggcaaa tccaattaga acagaagctg
    22921 ctcctacagc gtatttacga atagaaaaac gctgttgttt ttcatgtttc attgcaaaac
    22981 ctcctgattg cattgttata ttgatagcga ttatataaat caacgccttt attttatttc
    23041 ttatattaac gagagtcaag aggagatgac aaaaaactat aataagtata aaaaaatata
    23101 aaatttaaac ttaagatttc agattggtcg aaaaatacat atatatatct agtataattt
    23161 ttggttctat ttctataaaa tattccacaa attatagaat cttccaaaaa taggtaagcg
    23221 ctaccttttt ggtgtggtat aataagcata gaaaaagccc gagcgattag gctcaggctt
    23281 tcttcttagt gatcacggtc acatgagatg aatttaatct tgtagtaatc agatcgtttg
    23341 taagtttcac tgtattctaa aacttggcca gttgattcga gtttggtgat tttagtttgt
    23401 aggacagtag ggaattgttc atcgactccg aggactgaag ccgcatgttc tggagttgga
    23461 aagactattt cgttgatttc ttcaaagtgt tcatcattca tgtgaatgtg gtagtctaac
    23521 ttgaaacgat tatagataga actatagtat tcaaggtttg gataatttgc gttgatatat
    23581 tgttctggga tgtaggatgt atggtagata taaacgacac cgtttgattc gcggatacgt
    23641 tcaatcttgt agtagaattg atcgccgcgt agacccaatt tttccaagta aacaagcttg
    23701 tttccgcgtt caattgaaag aacagttacc ttatcatctt tagcattgaa gagctcaata
    23761 tctgaaaact ctacaagctt gtgtttgcgt gcacgtgaaa cgaaggttcc ttttccttgt
    23821 tggcggacaa tatagccatc tttggcaagg tcgtttaagg cgcgaacaac tgtgatagag
    23881 ctgacatcgt acattgaaat gagttctgct tcagtgtaaa atttatctcc actgctaaac
    23941 tgcccagaga tgattttatt ttttaattcg tcttttatgt attgatattt gggaattgcc
    24001 atatttttac ctctattttc cttctccata gaaaatttta ccataaaagc gaaaaaaata
    24061 gtagtctttt gaataaaaaa ttagaataat agtttgaaaa attaagcgat atagggattg
    24121 ctcatatttt atcaatgtat tctatacaaa attattttag gtcctatatt ccgaatttaa
    24181 agagcgtttg aaatgggtct aaaaatgttt gaaactaatt gaatgtgtgt ataatagtaa
    24241 aaatgcagta aatatcccga catttctatt gacaattcaa acagattggt ttataattaa
    24301 tataacaaca aatgaaagcg caaactttcg cggtcggaag gtagttttat gacacgattt
    24361 gagatacgag atgatttcta tctcgatgga aaatcattta agattttatc tggtgccatt
    24421 cattatttta gggttcctcc agaggattgg tatcattcgc tctataactt gaaggctctt
    24481 ggttttaata cggtagagac ttatgttgct tggaatttac acgagcctcg tgaaggtgag
    24541 tttcattttg acggtgatct ggatttagag aaatttctcc aaatagcgca ggatttgggt
    24601 ctctacgcaa ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt cggtggctta
    24661 ccagcttggc tcttgaccaa gaacatgcga attcgctcat ccgacccagc atatatcgag
    24721 gcagttggtc gctactatga tcagttattg ccaagactgg tgcctcgttt gttgaacaat
    24781 ggtggcaata ttctcatgat gcaggttgaa aatgagtatg gttcttacgg agaagataag
    24841 gcttacctga gagcgattcg acagctaatg gaagagtgtg gtgtaacctg tcccctcttt
    24901 acatcagatg gtccatggcg agctactctg aaagctggaa ccttaattga agaggacctc
    24961 tttgtaacag gaaactttgg ttctaaggca ccttacaact tttcgcagat gcaggaattc
    25021 tttgatgaac atggtaagaa atggccactc atgtgtatgg agttctggga tggttggttc
    25081 aatcgctgga aagaaccgat tatcacacgg gatcctaagg aattggcaga tgcagttcga
    25141 gaggttttgg aacaaggctc tatcaatctt tacatgttcc acggtggtac aaactttggt
    25201 ttcatgaatg gttgctcagc tcgaggaact ttggacctgc cacaagttac atcttatgat
    25261 tacgatgccc ttctggatga agaaggaaat ccaactgcta aatatcttgc agtcaagaag
    25321 atgatggcaa cacatttttc agagtatccg cagttggaac cactctacaa agagagtatg
    25381 gagttggatg ctattccact agttgaaaaa gtttctttgt ttgaaacctt agatagcttg
    25441 tcaagtcctg tagaaagtct ctatcctcaa aagatggagg agctgggaca aagttatggc
    25501 tacctacttt atcgaacaga aacaaactgg gatgcagaag aagaaagact tcgtatcatt
    25561 gatggtcgag atagggccca gctgtatgtc gatggtcagt gggttaaaac tcaatatcag
    25621 acagagattg gggaagatat tttttatcaa ggtaaaaaga aagggctatc taggttagat
    25681 atcttgatag aaaatatggg gcgtgtcaac tatgggcata agttcttagc ggatacgcaa
    25741 cgtaagggaa ttcggacagg ggtctgtaag gatctgcatt tcttactaaa ctggaaacac
    25801 tatccactcc cactagacaa tcctgagaaa attgattttt caaaaggatg gactcaagga
    25861 caaccagcct tttacgctta tgactttaca gtcgaagagc caaaagatac ttacctagac
    25921 ttgtctgagt ttggtaaggg agttgccttt gtcaatgggc agaatctagg acgtttttgg
    25981 aacgttggcc caactctctc actttatatc cctcatagct atctcaagga aggtgccaac
    26041 cgtatcatta tctttgaaac agaaggtcaa tataaagaag agattcattt aactcgtaaa
    26101 cctacactaa aacatataaa gggggaaaac ttatgacaat tgtaggatgc cgtattgatg
    26161 gacgtttgat ccacggacaa gtagccaatc tttgggctgg aaaactaaat gtttcacgca
    26221 ttatggttgt agacgacgaa gttgtcaaca acgatattga aaagagtggt ttgaaacttg
    26281 cgacaccacc aggtgtgaaa ttgagtattt tgccagttga gaaagctgca gccaatattc
    26341 ttgctggtaa atacgatagc caacgtctct ttatcgtggc tcgtaaacca gaccgcttcc
    26401 ttggtttggt agaagcaggt gtaccacttg aaacccttaa tgttgggaat atgtctcaaa
    26461 caccagaaac tcgttctatt acacgttcta tcaacgtagt agacaaggat gtggaagact
    26521 tccacaaact ggcagaaaaa ggtgttaaac ttactgctca gatggttcca aatgatccaa
    26581 tttcagactt tttgagctta ttaaaatagg aaaaaaattt ttaggaggtc attgttatga
    26641 tacaatggtg gcaaatttta cttctcactt tgtactcagc ttatcaaatc tgtgatgagt
    26701 tgacgatcgt ttcatctgca ggttctcctg tatttgctgg tttcattact ggtttaatca
    26761 tgggagatgt gactactggt ttacttatcg gtggtaactt gcaactgttc gttcttgggg
    26821 ttggtacctt cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt cttgcgacag
    26881 ccttctctgt ttcacaagga attgatgcac cgcttgccat tactacaatc gctgtaccag
    26941 tagcagctct cttgacttac ttcgacgttc ttggtcgtat gactactacc ttcttcgctc
    27001 accgtgtgga tgctgcaatc gaacgctttg actataaagg tattgaacgc aactacttgc
    27061 ttggtgcgat tccgtgggct ctatctcgtg cccttccagt cttctttgcc cttgcttttg
    27121 gtggtgcctt tgtacaatca gtagtagact tcgttgaagc ctacaaatgg gttgcagatg
    27181 gcttgacact cgcaggacgt atgcttccag gtcttggatt tgcaatcttg cttcgttacc
    27241 ttccagttaa acgtaacctt cactaccttg ctatgggatt tggtttgaca gctatgttga
    27301 ctgttcttta ctcatatgta acaggtcttg gtggcgctgt tgctggtatc gtaggtactc
    27361 ttcctgctga agttgctgaa aaaattggtt tcgtgaacaa cttcaaaggt ttgtctatga
    27421 ttggtatttc tatcgtaggt attttccttg cagtgcttca cttcaaaaat agccaaaaag
    27481 tagttgtagc agcaccttct acaccatcag aaagtgggga aatcgaagat gacgaattct
    27541 aattacaaac ttacaaaaga agattttaat caaatcaaca aacgtagctt gtttactttc
    27601 caattaggtt ggaactacga acgtatgcaa gcttctggtt acctttacat gatcttgcct
    27661 cagttgcgta aaatgtatgg tgatggaact cctgaattga aagaaatgat gaaagttcat
    27721 actcaattct tcaatacttc gccattcttc cataccatta tcgctggttt tgaccttgcc
    27781 atggaagaaa aagatggtgt aggttcaaaa gacgccgtta acggtatcaa gacaggtttg
    27841 atgggaccat tcgctcctct tggggataca atctttggtt cacttgtacc tgctatcatg
    27901 gggtcagtcg cagcaactat ggctatcgct ggccaacctt gggggatctt cctttggatt
    27961 gcagttgcag tagcgtatga catcttccgt tggaaacagt tggaatttgc ttacaaagaa
    28021 ggggttaacc ttatcaacaa catgcaaagt accttgacag ctttgattga cgctgcatct
    28081 gtacttggtg tcttcatgat gggtgctctt gtagcaacag tgattaactt tgaaatttct
    28141 tacaagttgc caatcggtga aaagatgatt gatttccaag acatcttgaa ccaaatcttc
    28201 ccacgtttgc ttccagcaat ctttactgcc tttatcttct ggttgcttgg taagaaaggt
    28261 atgaactcta ctaaagctat cggtattatt atcgtacttg ctttggctct ttctgccctt
    28321 ggtcactttg cacttggaat gtaattcctt atgactaaat cattaatttt ggtgagccat
    28381 ggtcgcttct gtgaggagct tagaggtagc acagaaatga ttatgggccc acaagacaac
    28441 atttacacag tagctcttct tccagaagat ggcccagaag aatttactgc taaatttgaa
    28501 gctgttattg aaggattgga tgatttccta gtttttgcgg atcttctcgg tgggacacct
    28561 tgtaatgtgg tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta cgcagggatg
    28621 aatcttccaa tggtgattga atttatcaat gcgagcctta caggcgcaga tgcggactac
    28681 aagagccgtg ctgcagaaag cattgtgaaa gttaatgacc tgttagcggg cttcgatgat
    28741 gacgaagatg aataatactc ttcgaaaatc tcttcaaact acgtcaacgt cgccttgccg
    28801 taggtatatg ttactgactt cgtcagtctt atccggcaac ctcaaaacgg tgttttgagc
    28861 tgacttcgtc agtcttatcc ggcaacctca aagcagtgct ttgagcagcc tgcggctagt
    28921 ttcctatttt agttggaact cgattcaatt catgtgacaa cgtgaaaatc gttagagcat
    28981 tttatataga atatacatgg gaatggagct tactcccatt cccatattta atagaaaaag
    29041 aggaactcaa tgctacatta tacaaaagaa gacttgctcg aattgggtgc agaaatcact
    29101 acgcgtgaaa tctaccaaca gcctgatgta tggagagaag cttttgaatt ttatcaagca
    29161 aaacgtgaag aaattgcagc ctttctacaa gaaatcgctg ataaacatga ctatattaag
    29221 gttatcttga caggtgctgg gacttctgct tatgtgggag ataccttgct accttacttt
    29281 aaggaagtct atgacgaacg caaatggaat ttcaatgcta ttgcgacaac agatatcgtt
    29341 gccaaaccag caacctattt gaaaaaagat gtggcaactg tccttgtgtc ttttgctcgt
    29401 agtgggaact cgcctgaaag tgtggcgact gttgatttgg ccaaatcctt ggtggatgag
    29461 ctttatcaag tgacgattac ttgtgcagca gatggtaaat tggctcttca agctcacggt
    29521 gatgaccgta atctcttgct cttgcaacca gctgtctcta atgatgctgg atttgccatg
    29581 acttctagct ttacgtctat gatgttgaca gctctcttgg tctttgatcc tacagaattt
    29641 gctgttaagt ctgaacgttt tgaagttgta tctagtcttg cccgtaaagt tttagacaag
    29701 gtagaagatg tcaaagagct cgttgattta gactttaacc gtgtcatcta tctaggcgct
    29761 ggtcctttct ttggacttgc tcatgaagct cagctcaaga ttttggaatt aactgctggt
    29821 caagttgcga ccatgtatga aagcccagtt ggcttccgtc acggtccaaa atctcttatc
    29881 aacgacaata cagttgtttt ggtctttggt acaacgacag cctacactcg taagtacgac
    29941 ttggacttgg ttcgtgaagt tgctggtgac cagattgctc gtcgtgttgt gcttttgagt
    30001 gatcaagctt ttggtcttga aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg
    30061 aatgatattt accgtgtctt cccttacatc gtttatgccc aactctttgc cctattgact
    30121 tcactcaagg tagaaaataa accagataca ccgtctccta caggtacagt aaaccgtgta
    30181 gtacaaggtg tcataattca cgaatatcaa aagtaagaca gtgtttatga attcttgaca
    30241 agaggatttg taaattatca gataaaccat agattgtcag tacgctttct atggtttgtt
    30301 tgcttgagag aaatagtaaa aggagaacag aatgaaagca tacacagagc gtgtatttgg
    30361 aaatgttgag ggcgaggatg tcttggccta tcgatttgag acagacggtg gctaccaact
    30421 tgaggttatg acttatggtg cgaccatctt gcgctatgtc gcacctgaca aggctggaaa
    30481 ttttgccaat gttatcttgg gatttgatga ctttgatagt tatgtaggca atagtcccaa
    30541 gcatggagca agtgtaggtc ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa
    30601 tggtaagacc tatgaccttg aggttaataa tgctagcaac tgtaatcaca gtggttcaac
    30661 tggttgggat tccagcttgt ttgaagttga agaagtaagc gatcatggct tgactctcta
    30721 cacagagcgt acagatggga caggagggtt ccctggaaat ctcaagattt ggattagtta
    30781 tcacttggaa gaaactggtg cctatgaaat cagctacaag gtaacgaccg atcaggatac
    30841 gctggtcaat ccaaccaacc acagctattt caacttgtct ggtgatttca cgcagacgat
    30901 tgaccgtcat gtcttccaac taaacacaga gggcatttac tcaatcgctc ctgacggtgt
    30961 tcctgccaaa actccagaag ccaaccgtga tgtggtcaaa cacatctaca atggtgcctt
    31021 gttgaaggat atctttgcag aagaagatga gcaaatccag ctggcatcag gtttggatca
    31081 tccatttgcc cttcctgcag gccatgacaa tgctggattc ctttatgacc aaaattcagg
    31141 tcgcttcctg cttttcaaga cagaagctcc ttgctttgtg gtctacacag caaactttgt
    31201 ggatgaaagt gtcatcatag gaggtcagcc aatgctacag cacaatggga ttgctcttga
    31261 agcgcaagct ttaccagatg ccattcacag tgaccttaaa ggccaagtca ttcttaaagc
    31321 tggtcaaacc ttcaccagta agacacgtta tgaacttgtt gtgaaataaa aaagctggtc
    31381 aaaaagtctt taaaattaaa ataacgcata ttgtcaggtg atgaaaagtt tgatactatg
    31441 cgttttatta tgaaatgatt tactttatct tatcctgaaa tggtgttatt tttgagttat
    31501 ctggcttgac tttcttgatg gaaattatat aatagttgta ataacaataa ttacaactag
    31561 aaaagaggac catttatgac ctatgaatac aagagtcaca tttatttggc agagacagtt
    31621 ttaaatgtaa aggatttggc cagtcaaaca gccttttatc agcaagttat tggtttagaa
    31681 atcttatctc aaactgagac agagtccatt ctaggccttg gtggaaaagt cttggtacag
    31741 ctgattcaag cacaagagag cggagaagtg agggaacatt atggtcttta ccatttggcc
    31801 attctcttgc ccacacgcaa ggctttggct gatgtcttga aacacctgac agatttgcaa
    31861 attcctcttg tcggcggtgc agaccatggt tacagtgaag ctatttactt ggaagatttg
    31921 gagggaaatg gcattgaact ctatcgagat aagccagttt ccacatggga tattcgagaa
    31981 gatggacgca ttatcggagt gacggaggct cttgcggcgc aggacattta tgagttgggg
    32041 gaaagagtag agccctttat cctggcagaa ggtacaagaa tggggcatat tcatctttcc
    32101 gtcaaggata gtcgaaagtc cagccagttt tatcaaaagg tgttagggct agagaataaa
    32161 ttcagtgtgc ctggcgctag ttggattgcg gctggagatt accatcatca tttagcagtt
    32221 aacgaatgga gaggaaaagg tctggcttcg cgtaagcaag gcttaccagg tttagcctac
    32281 tatgtcatcg aagtcgcaca taaaaaagaa ctgttaacga ttgcccaacg agcacaagaa
    32341 gttgacgcac caatcaaatg gatgacatcg agcaaattgg aaatcacaga ctcagatggc
    32401 atcgtgaccc gtattcgttt agcaaggtaa aattaggaat ttctaataag ttataagtat
    32461 tgctagtttg ctttttgaac ggtctttggt aacagaactg cgtgagctgg atgggtgaga
    32521 attttgacaa agaagctgat tagagatata atgaagaaaa atcgagcaag gaaaaagaaa
    32581 tgacaaattc aaagtatatt acttgtttga aacgttcaga gggccagttg tgtgggattc
    32641 aaaagatgat tgaaggagat cgtgactgtg ctgatattgt gacgcaactg acagcagtga
    32701 gatctagtgt agagcgcgtg attgagatga taattaccga aaatcttact gaatgtatca
    32761 atcagccact agatgattct gaagctcaaa aggaacgcct agaaaaggct atccgatact
    32821 tgattaaacg gaaataaatg aatgttttga gacgatatgt gcaaaggtct attaactatt
    32881 agaatagttt aatgtgagtc aaaagaagtt gtaaaaaatc tttaaaatta aaaaaacgca
    32941 tagtatcagg tgttgaatgt actgaccccc aaaagttaga ttttttctgt ctaacttttg
    33001 ggggtcagtt cataagaacc ttggtaatat gcgttttatt atgtagagac ttatactctt
    33061 cgaaaatctc ttcaaaccac atcagcttca ccttgccgta
//
LOCUS       DAVLHB010000020        32514 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLHB010000020 DAVLHB010000000
VERSION     DAVLHB010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.020"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(418..1107)
                     /gene="rplA"
                     /locus_tag="VXE36_001063"
     CDS             complement(418..1107)
                     /gene="rplA"
                     /locus_tag="VXE36_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0779383.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1315..1740)
                     /gene="rplK"
                     /locus_tag="VXE36_001064"
     CDS             complement(1315..1740)
                     /gene="rplK"
                     /locus_tag="VXE36_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0779384.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1863..2579)
                     /locus_tag="VXE36_001065"
     CDS             complement(1863..2579)
                     /locus_tag="VXE36_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0779385.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2597..3058)
                     /locus_tag="VXE36_001066"
     CDS             complement(2597..3058)
                     /locus_tag="VXE36_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0779386.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3060..4097)
                     /locus_tag="VXE36_001067"
     CDS             complement(3060..4097)
                     /locus_tag="VXE36_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0779387.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4195..5520)
                     /gene="brnQ"
                     /locus_tag="VXE36_001068"
     CDS             complement(4195..5520)
                     /gene="brnQ"
                     /locus_tag="VXE36_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0779388.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5691..5783)
                     /locus_tag="VXE36_001069"
     CDS             complement(5691..5783)
                     /locus_tag="VXE36_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0779389.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5826..5978)
                     /locus_tag="VXE36_001070"
     CDS             complement(5826..5978)
                     /locus_tag="VXE36_001070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0779390.1"
                     /translation="MKEIAFDAFYQLYQNDQFSLVDVREVDEFAALHLEGAYNLPLSQ
                     LADSYD"
     gene            complement(6138..6716)
                     /locus_tag="VXE36_001071"
     CDS             complement(6138..6716)
                     /locus_tag="VXE36_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0779391.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLSAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6770..8170)
                     /gene="pepV"
                     /locus_tag="VXE36_001072"
     CDS             complement(6770..8170)
                     /gene="pepV"
                     /locus_tag="VXE36_001072"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0779392.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8183..8788)
                     /locus_tag="VXE36_001073"
     CDS             complement(8183..8788)
                     /locus_tag="VXE36_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0779393.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            8959..9759
                     /locus_tag="VXE36_001074"
     CDS             8959..9759
                     /locus_tag="VXE36_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779394.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINSWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9943..10776)
                     /locus_tag="VXE36_001075"
                     /pseudo
     CDS             complement(9943..10776)
                     /locus_tag="VXE36_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10766..12613)
                     /gene="uvrC"
                     /locus_tag="VXE36_001076"
     CDS             complement(10766..12613)
                     /gene="uvrC"
                     /locus_tag="VXE36_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0779395.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEIYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12653..13354)
                     /locus_tag="VXE36_001077"
     CDS             complement(12653..13354)
                     /locus_tag="VXE36_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0779396.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13433..14665)
                     /gene="murN"
                     /locus_tag="VXE36_001078"
     CDS             complement(13433..14665)
                     /gene="murN"
                     /locus_tag="VXE36_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0779397.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14670..15890)
                     /gene="murM"
                     /locus_tag="VXE36_001079"
     CDS             complement(14670..15890)
                     /gene="murM"
                     /locus_tag="VXE36_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0779398.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVDQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16002..16781)
                     /locus_tag="VXE36_001080"
     CDS             complement(16002..16781)
                     /locus_tag="VXE36_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0779399.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16850..18511)
                     /locus_tag="VXE36_001081"
     CDS             complement(16850..18511)
                     /locus_tag="VXE36_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0779400.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18686..20908)
                     /gene="recJ"
                     /locus_tag="VXE36_001082"
     CDS             complement(18686..20908)
                     /gene="recJ"
                     /locus_tag="VXE36_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0779401.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21185..21943
                     /locus_tag="VXE36_001083"
     CDS             21185..21943
                     /locus_tag="VXE36_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0779402.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            21954..22747
                     /locus_tag="VXE36_001084"
                     /pseudo
     CDS             21954..22747
                     /locus_tag="VXE36_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            22760..23437
                     /locus_tag="VXE36_001085"
     CDS             22760..23437
                     /locus_tag="VXE36_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0779403.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQV
                     NKKAYSL"
     gene            23447..24106
                     /locus_tag="VXE36_001086"
     CDS             23447..24106
                     /locus_tag="VXE36_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0779404.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISNLSHMLAKRWQQAA
                     E"
     gene            24250..25440
                     /locus_tag="VXE36_001087"
     CDS             24250..25440
                     /locus_tag="VXE36_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0779405.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25761..26642)
                     /locus_tag="VXE36_001088"
     CDS             complement(25761..26642)
                     /locus_tag="VXE36_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0779406.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26783..28111)
                     /gene="vncS"
                     /locus_tag="VXE36_001089"
     CDS             complement(26783..28111)
                     /gene="vncS"
                     /locus_tag="VXE36_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0779407.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28108..28764)
                     /gene="vncR"
                     /locus_tag="VXE36_001090"
     CDS             complement(28108..28764)
                     /gene="vncR"
                     /locus_tag="VXE36_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0779408.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28813..28899)
                     /gene="pep27"
                     /locus_tag="VXE36_001091"
     CDS             complement(28813..28899)
                     /gene="pep27"
                     /locus_tag="VXE36_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0779409.1"
                     /translation="MYEKGFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29075..30454)
                     /gene="vex3"
                     /locus_tag="VXE36_001092"
     CDS             complement(29075..30454)
                     /gene="vex3"
                     /locus_tag="VXE36_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0779410.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMVLASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30506..31153)
                     /gene="vex2"
                     /locus_tag="VXE36_001093"
     CDS             complement(30506..31153)
                     /gene="vex2"
                     /locus_tag="VXE36_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0779411.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31166..32443)
                     /locus_tag="VXE36_001094"
     CDS             complement(31166..32443)
                     /locus_tag="VXE36_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779412.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9202 a         7434 c         6048 g         9830 t
ORIGIN      
        1 caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact atagtagatt
       61 gaaactagaa tagtacacct ctacttctaa aacattgtta gaaatcgatt tgactgtcct
      121 gaacgattcg tcctattctt atttcatttt attataattg atagtggtcg ccccagccag
      181 ataccttatc cgctatatag gccttattat cacgttcctg ttcgtagagc cacgatttcg
      241 ccatcccttc ctctgacgat tcttatttcc agcgtcagac ttgggaatcg ctattgggtt
      301 caccggtagt aggtgcccac cgaggactta cacctcagat atacgacatg cccgtcgtac
      361 atcaaaaaaa gttgagacat agtgtcttca acttttttac attactttaa ctactgatta
      421 aagtgagttt acgtcaactt tgataccaac accttgagta gttgtgatag tcaagtttgt
      481 tacgtaagtt cctttagctg tagctggttt tactttttgg attgtttcgt tgaaagcttt
      541 aaagttttca accaattttt cagcttcaaa tgatacttta ccgatgattg cttgaacgtt
      601 acctgcacgg tcagcacggt aagtgatttt accaccttta gactcttcaa ctgctttagc
      661 aacatccatt gttacagtac cagttttagg gtttggcatc aagttacgtg gtccaaggac
      721 acgtccaaga cgtccaacaa gagccatcat atcaggtgta gcgataacta cgtcgaagtc
      781 caaccaaccg tcgttgattt tagcaacaag gtcatcttca ccaacaaagt ctgcaccagc
      841 agcttttgct tcttcagctt ttgcaccacg tgcgaaaaca agaacacgtg aagttttacc
      901 agtaccgttt ggcaatacca ttgctccacg gatttgttgg tcagcttttt taacgtcgat
      961 gttcaagttg taagcaactt ctacagttgc atcaaatttt gcaaagttag tttcttttgc
     1021 aagtgctaca gcttcttcta cactgtatgc ttttgtgctg tcgattttct caagagcagc
     1081 acgaagttgt ttgctttttt tagccatttt ctattctcct tgtaagtggt tcaatcgatt
     1141 ttcatctccc acgtcacttc tcgaaatgat gaagtcttgc gggttttcag tctactattt
     1201 ttctcttcct acggccttaa gctcccttgc tgtatccaag tacaagcctc agtcacttgc
     1261 ctagtatgaa aagcaactaa tagactgctg tgagattttc tactgtgtta ttgattagtc
     1321 aacaacagtg aatcccatag aacgagcagt accttcgatc atacgcattg cagactctac
     1381 gtttgctgcg ttcaaatctg gcatcttagt ttctgcaatt tcttgtactt gtgcacgagt
     1441 aactgtagca actttagttt tattaggtgt acctgatcct ttttcaacac ctgcagcttt
     1501 tttcaaaaga acagcagctg gtggtgtttt cgtaacgaaa gtaaatgatt tatcttcgta
     1561 aactgagata acaactggaa tgatcatacc agcttggtca gctgtacgag cgttgaactc
     1621 ttttgtgaat cccatgatgt tgataccagc ttgaccaaga gcaggtccaa ccggtggagc
     1681 tggtgtagct ttaccagcag ggatttgcaa ttttacaagt ttttcgactt ttttagccat
     1741 ttttaaatcc tcctttgtgg ttttggcggt aattagagat ttttacctcc cacaagtatg
     1801 ctttacacat acctttccat tatacactat ttatctaaaa atgcaagaga aaactttcat
     1861 ttttaatcga cataatcgcc gccttcaaag ccatagtact cttccaaact gagaccactt
     1921 gcagcaattt ctttggcttc ttttccaacg tagcggagat gccattcttc tgccatgtag
     1981 ccagtctcct tttccttgcc tttaagatag cgaacaacaa agccatagtc agccgcatgg
     2041 tccaagagcc actgggctgc cttttcttca gtaactaaat ccccatctgt cccaatcaaa
     2101 tcaaaagcaa gacccgtctg gtgttcactg taacctgggc gtgctgagta gcgatctgct
     2161 gcttccttac catcttgatt gacatagtct tggtagagct tagcctgagt ttcataactc
     2221 ctaaacccac tgtattggtc actgattgga tagccctcag cctgcatagc tgcgattagt
     2281 ttgagcaact ctgccttggc tgttggattt tctcctggat tgtaatcttt tgacaaagga
     2341 taacgtttat tagctaggat aatctcatcg tatttccctt ggatactata atagctccct
     2401 ttattgctaa cttctgcctt tttctgacta gaagcttgag atttgctacc tacagttcct
     2461 tccggttgac tgctttgctc cgttttttga gtgttttctt caactttggt tttttcttgc
     2521 gaacaagctg caagggtcaa tgctagtaaa ccagataaaa tgacatatct ttttttcatt
     2581 tctttcttcc tctctcttag gccaaatact tctccaattc atgagataag attttaatca
     2641 tctcttccag ctctggcgat tgtacttggc aatcttctgc cgccatttct tcccagggca
     2701 cccaccagac tgggccacgg ccattcaaac cgtgactctt catatcacct gctcttcggg
     2761 gaaaaagatg ccaatgagcg tgggcatcgc catttcctag gagttcaata ttcatctttt
     2821 cagcctcaaa tgctttggcg actgcttctt ggactaaact catttcctct aaaaagcgaa
     2881 gttttacaga agtttccata tgatggagtt ctgtgacatg atcttttgct aaaaataagg
     2941 tatagccctt aaagtattgg tagtcaccaa taacaacata gcctgtttct agttctttta
     3001 caaagtaggg attttgccca gctttaatga gttcgattct ctgacagatt aagcacattc
     3061 tatgataccg cctcgctctt aagataagca tcaaccatac gctcagtcgc tattactgaa
     3121 tcgatgtggg tgcgctcata agagtgactg gactcaatac cagctccaag aagtgcatgc
     3181 ttgacctctg cacctgctga catcgctgct gaagcgtccg atccgtaaaa tggatagatg
     3241 tcgagcttaa atggaatatc ttgctcttta gccaaggcaa ccaagtgttg acggaagtca
     3301 tagtgataag gacctgaagc atccttgaca cagatagata ctgtgtactc atctgtctgc
     3361 tggtcatctc ccatagctcc catatccaca gccagatatt ctactacctg agcaggaatg
     3421 ttagaattag caccatgtcc tacttcttca aaaactgaaa aagcaaaatg agttgttact
     3481 ggcaattcaa tcttctcttt cttataaata cgaagcaggt tgagcaaaat cgctgcgctg
     3541 accttatcat ccaaatgacg agacttgata aaacctgtat cagtcacaac agttcgtgta
     3601 tcgaagctga taaaatcacc gacctcaatc ccaagagcac gagtttcttt ttcattgctt
     3661 acttttacat ccaaacgcac ttccatattg tcctgcgtgc gttctgcagt tcctgcatcc
     3721 ttgtagacat ggcaagaagt ttggtggatg aggatggttc ctgatacctt ttgacctgtg
     3781 ctagccacat gaacggtaca gttttcacct tcaatcatgt tccaaggaaa accaccgata
     3841 cggtccaatt taagacgacc atctggtttg acagcacgaa caatagcacc cagcgtatcc
     3901 acatgggcag tcacatagcg atgttgctca tcattttgac ctttgatggt cacattgaca
     3961 ccacccttag ctgtgcgaac tggctggtaa ccaaaacctt ctagagtctt gactaaataa
     4021 ttcgaaattt cacgagtgaa gcccgttggc gatgcgatgg ctgtcagttc tttgatatat
     4081 tctactgttt gattcatttc ttcacctctt tcgctaccta ttataacaca tttatcatcg
     4141 gataaaaaaa gaaaatcact cctgtagact tggctacaaa agtgatttaa gtgattattc
     4201 catttcaaaa acatcgcttt cttgcttgtt tggtagaacc aatgagagca agattccaac
     4261 aatggctggc accaaccatg ggagagatgc cttggcaaaa ggaagaacgc taacaagatt
     4321 tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt gcaatggcaa taactgtaac
     4381 cacagcaatt gtcaactgca tacctggttt tgaaagggca acaaatttgt tgacaatgac
     4441 aatcataacg atagcaatcg tgattgggta caagataacc agtactggaa ttgagtactt
     4501 gataatcgca tcaagaccca aattggcaat agcaaatcca atcaaggtaa aggctgtcgc
     4561 ataaaccttg tagctgattt gtgggaagcg ctcattaaag aactcagctg ttgacacaat
     4621 caaaccaaca gtcgttgtga agcaggttac ggtaaccata gctgcaagga agagttgagc
     4681 tgttgagcca aagatttctt gagtggcttg tgacaagatg taaacacctg gtgttccacc
     4741 cttcatcgct tcagctggta ctgggaaatg atttccaaga aaacctaaac cgatgtaaag
     4801 agcgctgaag gcaagggcaa caacgatacc aacaacccaa atagttgaaa tgtattcttt
     4861 cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg attacgctaa aggccactga
     4921 agcaagggcg tccaaggtat tgtaaccttc taggaaacct gtaccaaagg cagaagcttg
     4981 ataagcagct gaagcagctt gaggacttgt tccaccatat ttgatagctc ccagaacgac
     5041 caagataaca atcaaaattg caaagactgg cgttaaaaca cgtccaatgc ggtctaagat
     5101 ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa tacagaaccg taaatacaat
     5161 caagccaagt cctttatttg catccgacaa aagggggcta atccctactt cgtaagctgt
     5221 tgtagcagta cgtggggtag caaagaatgg accgattgac aagtaaagaa ctgagaggta
     5281 aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg tagatatatc ctttaggatt
     5341 tagcgttcca ataataaggg tcaagacggc gataccaacg cctgaaaaga caaaacctgc
     5401 gatggcagga agaaaatgtt ctccagatag agcacctaga gaaggcggaa aaatcaagtt
     5461 ccccgcacca aaaaatattc caaacaggag caaacctgtt agggtacctt ttttagccat
     5521 aaaaatctcc ttcatattta taaaatactg acctagtata ccacgattag gagtctgaaa
     5581 aaagcatcac gaggcaaata ttaaatgttt tcaattttct taaaaataag aattatctaa
     5641 aaataaaact ctcctaccca gtccacacca agtaggagaa atgcaaaatt ttaaagttct
     5701 tcaaaggcta acatgccacc ctggacattg ataacattat aaccttgttc taataggaat
     5761 tggcaagcac gcgccgatct cattccagat ttgcaaataa tataatgcaa gcgatctttg
     5821 tccaattaat cataactatc agccaattga ctaagcggta ggttgtaggc accttctaaa
     5881 tgaagagctg caaactcatc cacttctctc acatccacta gagaaaactg atcgttttgg
     5941 taaagctggt aaaatgcgtc aaaggctatt tctttcattc tttttcttct aatactcttc
     6001 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtgc gtatgttacc gacttcgtca
     6061 gttttatctg caacttcaaa gctgtacttt gagcagccta cgactagctt cctagtttgc
     6121 tctttgattt tcattgacta taaaatggtt ttaattcttt ttttcaaatc tggcactact
     6181 tctgcctcaa accaaggatt tttggccatc cagatttgat ttcgtggtga tgggtgaact
     6241 agcggaaaat aggctgacag atagtcttta tagtgtttca ccctctccgt taccttccca
     6301 ctgattttct cctgtaaata gtaggcttgg gcatattgcc caatcaagag ggttaactga
     6361 atatcaggca attcctgtaa gagttgcgga tgccattttt ctgcaaaacc tgtacgaggc
     6421 ggaagatcac ccgacttgcc atgtcctgga aagtagaaat ccataggcaa aacagcaaaa
     6481 taacctgaat tgtaaaaggt atcttcatcc acacctagcc agtcccgcaa gcggtcacca
     6541 cttttatctt tccagtaaag gcctgcttct tgagttttaa gtcccggagc ctgaccgatg
     6601 atattgatgc gagcagtttt tggcgctgca aagagaggct caatgccacg ctctgtatag
     6661 ctggcattct gtgaatccgc catgatagcc tgtttgattc tttcgatttg agacatctac
     6721 tttccctcca aaaagaagtc caagcataag atctcagact tctatcgttt tatttgatca
     6781 attcataaat agcttcggca taaattgctg ctgctcggaa aagatcatcc aaggcgataa
     6841 attcattggc ttggtgcatg gtatcaatcg agtctgggaa catagcaccg taggcaactc
     6901 cgcgttctag caagcgacca aaggttccac caccgatgac ttgttcatga cctttaaggc
     6961 cagtttgttt ttcatagaca ttcaacaagg tttgcacaag tggatcttcc attggcacat
     7021 agtgaggcgt gtgaccgtgt tcagacaggc taacagaaac aactggcaag ttttcaagga
     7081 ttgacttgat ttgttctgga cttgttcctt ttggatagcg gatgttgagg gcaatggtat
     7141 tatcagcact tgtttcatcg aagcggaaga cgccggcatt catagaaaga gcacccatct
     7201 tttcatccac atgagcaatc ttaagatttt caccctcatg atcgttcaag agaattttac
     7261 ctgcgatgtc aaggtagtct ttggctggac cagcaaagcc aaactggctg aggaagaggg
     7321 caaggtaagt tgcgccattg acacctgaag caggcatagc accgtgggct gatttaccaa
     7381 tgatcgtcac cttgtatttg ccagcttctt cttggagttc tcctctaagt ttgtgttctg
     7441 caacaaaggc atctagttta gcttgcaagt cagccaagtc acctgaaacg actgctgttg
     7501 ctgattctgg taccatattt tcacgtaaac cacctgtaaa gctgtgaaga cgggcaacac
     7561 ctgtattttc tcctgcaaag tggaggtatt ccgtgatatt tcctttttca ccattgatga
     7621 ttggaaattc agcatctggt gagaaaccga aatctggttt ggcaagtcct acgtgctcaa
     7681 agtagtagtc catgtctgcc cagcctgatt cttcgtctgt tccaacgatg aagcgaactt
     7741 tcttagaagt tggaagaccc aattctttga tgattttcaa accatagtaa caagctgttg
     7801 taggaccctt atcgtccgaa gccccgcgcg cataaaggcg accatctttg atagttggtg
     7861 tgtaagggtc tgtgtcccaa ccgctaccag caggcaccac atccatatgg gcaaagattc
     7921 cgagaacttc ttctccatca ccaaactcaa aatgtcctgc atagttatca acattcttag
     7981 ttgggtagcc atcgcgatct gcgatttcaa ggaatttctc caaggctttt actggaccag
     8041 gcccaaatgg atgctgggca tcagccttgc tgtcatcacg ttctgaatta atttccaaaa
     8101 ggctaaacaa gtcagccaag aggtcttctt tgcgtttttc tacttctgct gtaaaatcaa
     8161 ttgctatcat tttttcttct tcctatcttt tttcgatgat ttcatctact ggcaagcggt
     8221 agcttggttc caatttgtcg tctgtgtaac ccactgtgat caagagttct gggcggaaac
     8281 ggtcttcaat ttccaaaacc tcattgactt ttgatttgtc aaaaccaaga ataatgttag
     8341 aaccaattcc ttggtctgtc aatgcaagaa ccaagttcat agcaaccaaa cctgcattga
     8401 gtgctaggta gtcgctgact tgttgttcat tgtagcgtgc aaattcagct ggcaaatttt
     8461 tcatgaagta ttgaagttgt tcttctgaga aattgttagc accaccaact cgggcaatct
     8521 tacgagcgcg tttggcaagg tctgtatctg taaatagggc aatggttaca ggtgctgatg
     8581 atacctgctc aaagtttgaa ccataagcca actttgccag ttcagcattt ttctcacgaa
     8641 caactacaaa tttccaaggc tggctgttgt gggcgcttgg cgccaaggtt gcaatttcga
     8701 tagccgtacg cacatctttt ggatcaacag gcttatcagt gaaatgcttg gtcgcatgac
     8761 gttttttatt taattcaaga aatttcataa tcgatttcct tttctaattc tactgcttcc
     8821 attctaccat aatttgaaag agcttgcagg gatttttcat gattaagttt ttctatcaca
     8881 gacataaaag atatatattg gtttatcagg aaagtttctg ataaactagc aagtacttta
     8941 catttgaatg gagacagtat gaaaaaattt agcctattac tagctatcct accatttttg
     9001 gttgcctgtg ggaatcaagc tacacccaaa gagactagcg ctcaaaagac aatcgtcctt
     9061 gctacagctg gcgacgtgcc accatttgac tacgaagata aaggcaatct gacaggcttc
     9121 gatatcgaag ttctaaaggc agtagatgaa aaactcagcg actacgagat tcaatttcaa
     9181 agaaccgcct gggaaagtat cttcccagga cttgattctg gtcactatca ggctgcggcc
     9241 aataatttga gttacacaaa agagcgtgct gaaaaatacc tttactcgct tccgatttcc
     9301 aacaatcccc tcgtccttgt cagcaacaag aaaaatcctt tgacttctct tgaccagatc
     9361 gctggtaaaa caacacaaga ggataccgga acttctaacg ctcaattcat caatagctgg
     9421 aatcagaaac acactgataa tcccgctaca attaattttt ctggtgagga tattggtaaa
     9481 cgaatcctag accttgctaa cggagagttt gatttcctag tttttgacaa ggtatccgtt
     9541 caaaagatta tcaaggaccg tggtttagac ctctcagtcg ttgatttacc ttctgcagat
     9601 agccccagca attatatcat tttctcaagc gaccaaaaag agtttaaaga gcaatttgat
     9661 aaagcgctca aagaactcta tcaagacgga acccttgaaa aactcagcaa tacctatcta
     9721 ggtggttctt acctcccaga tcaatctcag ttacaataac actcttcgaa aatctcttca
     9781 aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccta cggctagctt
     9841 cctagtttgc tctttgattt tcatattgag tataagatat attaaaagcg atgggatcag
     9901 ccaatcgctt ttttagtttg cattggttat tttaggaaac tcttacaaaa aatcaaaaaa
     9961 attcttcaca tcctctacat acctatgctt ttctattaag cttgctaata gttccagatt
    10021 gtgcctctga tagttatctt cacgacgtag ttcttcatac atttcgataa agggaaaacc
    10081 cttggatttg gcaaattcta actcagcctc gtaatcataa gcgactttac gaaataggat
    10141 atttaccaat tccccatctt caacctctat cacggcatac tgggcacggt gattttttaa
    10201 cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga ttgatgattt gttgcccttg
    10261 actaccataa cgaagcaact acttgtgaac atgaccataa actgccacgt ccgtttccgc
    10321 atctagcagt tggtcaaatt tctctgtatc attctcaact agcaagtcac caccatagtt
    10381 tttgtcaggt aaattatgag agatagaaaa gcgcaatccg tcaatttctt tcttttccag
    10441 caaaggcaag cttcgtagcc agacaatcgt tgcaggatcc attcgctcca tcaaatactg
    10501 tgtcatacgc aagagctgaa cttcctgtgg gtcttctaag ccatattgcc catctaaagc
    10561 ctcaaggaca caatcatccc aattgcctcg aacacttgcc gtgataggaa gttcctttaa
    10621 cagagcgacc aagtcatttg cacctggacc agggaggaaa atgtctccca tgagccaata
    10681 ttcactggct ccttgagttt tagcatctgc aatcactgct tctagcgccg tcgcattgcc
    10741 atgaacatct gataaaattg cgattttatg gtttattgtg gtttccttcc gtttggtaat
    10801 ctactctttc ttccgccact tgaagcaaga tttctgtttc ctgcgggttc aacttggttt
    10861 gcacagcctc tgctactgct cttggtactc caacttcgac aatctcatcc acactggctt
    10921 ccttgatttt ggtcagagac ttgaagtgcc tcatgagatt ttgcttgcgt ttaggtccca
    10981 gaccatcaat cccatccaat tgagatgaga aagaattttt ggagcgcagt tggcggtgga
    11041 aggtaatggc aaagcggtgg acctcatctt gaatgcgttg gaggaggaaa aattcctgag
    11101 aattgcgaga caagtccacc acttccagcg gatctccaaa gagcaattca tgggtttggt
    11161 gcttatcatt cttttgcaga cctgcaattg gaatatccaa gcccagttct tcttggatga
    11221 cttgcttagc aatattgact tgaccttgcc ccccatcaat cacaatcaaa tctggaggag
    11281 tcaaagcctc acgctgtact cgaccatagc gtctgcgaat gacctctcgc atactggcat
    11341 agtcgtctgg cccgactacg gtcttgattt tatacttacg gtaatccttc ttactaggct
    11401 tgccgttgac aaagaccacc atggctgaaa caggactagt tcccatgatg ttggagttat
    11461 cgaaggactc gatgcgaact ggggttggga tttgaagcaa gcgtcctaga ttttcaatag
    11521 ctccttgggt cttctcgaca gatttctcta gcaggttgaa cttctgctct aggctaacac
    11581 gggcattttt tatagctaaa ttgaccagct gctttttctc tccacgttga ggcttaagaa
    11641 tcttggaatc caccaaggcc ttgacagcct cttcgtcaat atcttgcgga atcagtacct
    11701 cattgggaac tagatgggat ttttcttgat agaattgtcc tacataggtc aaaaaatcct
    11761 catctggatc attgaagtag gggaagagat tgacatcgcg ctcgatgagc ttaccctgac
    11821 ggacaaagaa aacctgcaca cacatccagc ccttatccac atagtagcca aagacatcgc
    11881 gattttggag atccttagcc atgacccgtt gcttggttcg aagcgttcca atagcctgaa
    11941 tcaggtcacg gtattccgcc gcacgttcaa actccatagt ctgggctgcc gctgccattt
    12001 tgccctttag ctcatcaatg attttgttat cctgcccttt cagaaaatca gaaacctcct
    12061 gggccataga cttgaaataa atctcatcct tcttacagat ggtgtgggcc atgcattgac
    12121 cgatatggta ataaaaacag accttagagg gcgggttggt acacttacga aaagggaata
    12181 tccgatccag caaccgcttg atttcattgg ctgcccccac atcgggatag ggtccaaaat
    12241 aaagacctcc gtcctttttg acctgacgag tgataatcaa gcgtggatag cgctcattgg
    12301 tgattttgat gaaaggatag gacttgtcat ccttgagcat gatattgtac ttgggcttgt
    12361 tttccttgat caggttgatt tctaggagaa gtgcctcaat attagactcc gtaacaataa
    12421 attcaaaatc cacaatttca gacaccagag cctctgtctt ggtatcatga cttccacgaa
    12481 aataggaccg tactcgatta cgcagatttt tagcctttcc tacatagata atggtgccat
    12541 ttttatcctt atgaatgtag caaccagggc tggtcggcaa gagctctagt tttgatttaa
    12601 tcaagttgtt catagttcca ttatagcaaa aaaagtaggg aaagatagta ccctactcac
    12661 tagtctcata tatttttcgg aggtttgcaa catcctcttc ctggatacca taaaaggaac
    12721 ctgctggttg catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact
    12781 catgttctgc cgtatggaca aggcgttcat aggagtagcc atagtatgga ttggacaaat
    12841 aataatgatt caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac
    12901 tttccgcctc tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg
    12961 ccttactaga ctcagtcacg agttcaaagt taaaagcacc agtttgattc cagttctgga
    13021 ttgcttctaa ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag
    13081 cagaggcctg tgcccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag
    13141 gcagttgccc tgttttctcc cattggtcaa tactttgttg accaattttt actgaccgtt
    13201 ctgcttgctt tagcgctcct tgaaaatctc cgttcagata ccagagaagt ccgaaagcaa
    13261 gcacacataa gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaagaaa
    13321 agaaagcccc tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataag
    13381 aattatttta ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc
    13441 ctactatttt tttgagtaac tggatagctt tgtattttaa aggagatgga tggtaacgga
    13501 aagtacctgc tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat
    13561 cacttccatc aaaaatccct tgaatgccta ggaagttgta tttaggtatt ccacgtttta
    13621 tgctttccaa cataacatat ttttgaagca gggcaggggc atagaactta ttaaactcag
    13681 tgtaggaacc actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactcccag
    13741 ctaaaacaat atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa
    13801 cttcaaacgt ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat
    13861 gaggattttt actcaaatca agtcgcaact tgtccaagtt ttcttctagt ttactttgtt
    13921 caccttgcaa tttgctcata tagtccgaaa aatttaagct tgctatgaga aactccgctt
    13981 gttctccaaa agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc
    14041 tacgttcaga ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact
    14101 ttttcaaccg aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa
    14161 aacttttaag caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg
    14221 gttctccacc tgggtaacct gttgttaagc catcaaattg ataacctaaa tcagtcaaac
    14281 cttgaataat actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat
    14341 aagtttcata aggttttaca agcaactcta atacaccatt ttgcttggca tattctttta
    14401 actctgcata aaaaactgga agagcatctt gttgggtata aattggcccc gaattgagtt
    14461 ccatatgcag accacccagc atgggcaagc tataaaccag agctgcaact tgaatttctc
    14521 cttcttgttt caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca
    14581 tctggacaga ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt
    14641 ctttcgtgag tgttgttagt gccatatact tactttctat gtttttttct taatgtttta
    14701 cggaaatcaa gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca
    14761 cccaagtatt cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg
    14821 agagagtttt caacaccacc taaattttgc cagaccatac ctcgctcaaa ggcatagcga
    14881 gccgtttcat accatgttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca
    14941 gcatatatat taacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact
    15001 ctcgcttgat ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct
    15061 ttttccttct tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa cgtctcttcc
    15121 aaggctctat ttttcgctaa ctgttcttct aattcttgcg aacgtttaga aacatccaag
    15181 gtggccaagg tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct
    15241 tcattcctca aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa
    15301 tctaatagtt ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata
    15361 gcctgttttg ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc
    15421 tgaatacgag gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc
    15481 atttgttgca aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg
    15541 attaaacttt gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg
    15601 cgagcatagg acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc
    15661 aatataggtc ctcttgggat gtaaaacatt ttatagccta gcggaagagt tctaatcaaa
    15721 atactagctg tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa
    15781 ttagacttaa cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg
    15841 acaaactgat catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct
    15901 ctttcctcca gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca
    15961 tattttattt tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct
    16021 aatttgaaat caattggtag ggttgttaaa aaaacttcca attgtttttc ccagtagtac
    16081 cactcgtgag ttccagcact atggctatag gtcacatcaa aacctagttt tttgagattt
    16141 ttcactgcga gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt
    16201 ttggtctttt tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag
    16261 tctctaatct ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca
    16321 ggagaaaagt tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt
    16381 gtcgtaagag ccagtttgaa gcagccgtag cctcccatag aaagaccagc gataaaggtc
    16441 ttttcacgct tgctagtcat attagggaag aagcgtttca gaacctgtgg caattcctct
    16501 gctagagccg tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta
    16561 ttgggcataa caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta
    16621 agccaactat tatgattgcc agacatcccg tgcaaaaggt acaagacggg aatatcttca
    16681 cactctggtt cttccactcg attggcatca gggtagagga cattcacccc ccactccata
    16741 tccaatactt gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt
    16801 tctataagaa aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt
    16861 ccatgactac tggtaaaata gctggacgac gcttggtttg gtcaaagaga tacttggtca
    16921 aattatctcg aaccttccct ttaagatctg cccagtcaaa gtcatctcct tgaagatact
    16981 cttctaccgt ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga
    17041 gataaacaaa tccacgcgtg tgaacacgag ccctagccac aattttcttc tcacgacggt
    17101 tgactgtaat agccacgatg aaaattccat cctctgacaa gaccttacgg tcacgaagaa
    17161 caacatttcc aacatcacca atggcattcc catcaatcaa gatatctcct gctgaaaccg
    17221 atccagctgg aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga
    17281 agatgcgttc tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac
    17341 gatactcccc ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca
    17401 aatcacgcac atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc
    17461 cacctgcctg ataaatcata ttttccacac gcgcaacaaa ggcttcttta gcaatagacg
    17521 gagccgtagc aatatagact aggtccccat ccttgatttc tacataacga tggcgaccaa
    17581 tcgacatctt acgaagtcca ttgataggct cacccatacg acctgtctca agaataatca
    17641 actcatggtc ttcaaagcga gacatatctt taggcttaat caaaagaatt tcgttggcta
    17701 aagacaactt cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca
    17761 agacgatacg tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat
    17821 tactggaaac agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt
    17881 catccctaac ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac
    17941 tgaggagagc caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat
    18001 aagattcact agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg
    18061 atgtcttcaa gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa
    18121 ccactgtccc accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt
    18181 tcttaacggc atcatttcct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc
    18241 caaatacagg aactttagcc tctgccaaga gatacggtag agcaccaatg gcatccgcat
    18301 gcccgtgggt caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt
    18361 ttggaatcac cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca
    18421 aaacaaaaat ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac
    18481 caccaagtgt tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga
    18541 ttatagggca attctaccct cttattctaa aagttctgat actttcagcc gaatcttttc
    18601 ctaccattat accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt
    18661 tgatttccca actctttcct aacttctact ctttttccat caaaaaatca taaatttctt
    18721 gcaccgtacc cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa
    18781 tttgactttc tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt
    18841 ttatcgtcac aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt
    18901 gaatattaag atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact
    18961 ggtaaatagt cttgtacaat ttggcaaact gatctctagt cccataacct gtcagataat
    19021 aagccttgtc aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg
    19081 tcttcagctg agtaatatcc tctggaatgt tttttacgac aacagcttca ctagccgcaa
    19141 gatttggcag ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt
    19201 ttccacgaat gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga
    19261 gggcagtttg gccattccat tggttgacag acaatttaac cgctaactct agattcttgg
    19321 tttgagaaaa ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct
    19381 cacccttgga aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt
    19441 cgacctgaaa attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta
    19501 aacgttcaaa acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta
    19561 ggtttaactt attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa
    19621 cctgagataa atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac
    19681 ctccaaaggc gatgaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt
    19741 ccacactacg agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct
    19801 gtcccaattc ttccaataaa cgaccagcca cgattcctag aaccccagga ttccagcctt
    19861 ccttggccaa gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga
    19921 tagactgaac gatttccttg cgctcttcgt ttttctggtg aatcataagg gcaatctcat
    19981 gcgcttcctc atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc
    20041 gacccaaggc attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt
    20101 tggcagcaat cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca
    20161 acatttccag accatattga actaagatac gattttcatc cgtcagactc accatatctg
    20221 caatagttcc aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac
    20281 aagccaactt gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg
    20341 gatgttcagg atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt
    20401 ctgtcacaat gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa
    20461 ccccattgtc caccgtcaca atcaaggaaa tcccttcttg ctcgataaag tatttataaa
    20521 cactagcatt agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag
    20581 caccaagttg ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat
    20641 agtctccata aacaagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg
    20701 ccttgtccat atcatggagc agataagcat catgtaagtc ctccaaggaa ggttctaaaa
    20761 acttcttcag actttcttgg ttctgaatcc ctctctcaaa caataaccga gccacctcag
    20821 gacccagtcc agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa
    20881 actgccattc ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg
    20941 cttcattata acatgattta gacgttttct ctatccagat tgctttttta taacatttta
    21001 tagtatattg aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt
    21061 gactgtcccg atcgattttt cctgttctta tttcactata gtgaattttt tcagatatga
    21121 tttgacaaga acattctttt attgtagaac cgtgttataa aatataacac aatagagatc
    21181 tctcatggct ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcatt
    21241 ccgcaacatc aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg
    21301 ctctgggaag tccactctta tccgtacgat caatggttta gagactgttg acaaaggaag
    21361 tctcctagtc aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg
    21421 caaggaagtc ggcatggttt ttcaacattt taacctttat ccacacaaag ctgtgttaga
    21481 aaacgtaacg cttgcaccca ttgaagttct aggaattgat aaaaaagaag ctgaaaaaac
    21541 cgcccaaaaa tatctggaat ttgtaaatat gtgggacaag aaagattcct atcccgccat
    21601 gctatctggt ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga
    21661 actcctcctc tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct
    21721 agcagttatg cagaaactgg cgcatgatgg gatgaacatg atcatcgtta cccacgaaat
    21781 gggctttgct cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt
    21841 agatacgaca gatgtcgata acttttttga caatccaagc gaacctcgtg cccaacaatt
    21901 cctcagcaaa attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa
    21961 aaaaattctt tttatcagca ttattgatta gccttttcag ccttgctgct gccaaaccag
    22021 tccaggctga tactagtatc gcagacattc aaaaaagagg cgaactggtt gtcggtgtca
    22081 aacaagacgt tcccaatttt ggttacaaag atcccaagac cggtacttat tctggtatcg
    22141 aaaccgactt ggccaagatg gtagctgatg aactcaaggt caagattcgc tatgtgccgg
    22201 ttacagcaca aacccgcgcc cccttctaga caatgaacag gtcgatatgg atatcgcgac
    22261 ctttaccatc acggacgaac gcaaaaaact ctacaacttt accagtccct actacacaga
    22321 cgcttctgga tttttggtca ataaatctgc caaaatcaaa aagattgagg acctaaacgg
    22381 caaaaccatc ggagtcgccc aaggttctat cacccaacgc ctgattactg aactgggtaa
    22441 aaagaaaggt ctgaagttta aattcgtcga acttggttcc tacccagaat tgattacttc
    22501 cctgcacgct catcgtatcg atgccttttc cgttgaccgc tctattctat ctggctacac
    22561 taataaacgg acagcactac tagatgatag tttcaagcca tctgactacg gtattgttac
    22621 caagaaatca aatacagagc tcaacgacta tcttgataac ttggttacta aatggagcaa
    22681 ggatggtagt ttgcagaaac tttatgaccg ttacaagctc aaaccatcta gtcataccgc
    22741 agattaagga ggatacccta tgacagattt atcatcttgg acagcctatt ttcaggattt
    22801 tggacaattt ttcaatggtt tcctcttcac ccttgcccta gcgattggat cctttatcct
    22861 cgccatggtc ttaggaatct tctttggtgc catgtcaacc agtaaacgtc caattttacg
    22921 cattttagct cgcatcttcg tggaatttta ccaaaacact cccctcttgg tgcagtttgt
    22981 tattgttttt tatggcctac ctcttatcag tgaccatatc atcatgattc caatttattg
    23041 gacagccgtt ctctgcgtgg gactctatca cggcgcttat atcgctgagg ttattcgttc
    23101 agggattcag tctattccta gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta
    23161 tatcagtgcc atgcgcttga ttatcttgcc tcaggccttc cgcatcattc tccctccatt
    23221 gaccaaccaa attgttaacc tcatcaagaa cacatctact gtagctatca tctctggagt
    23281 agacttgatg tttgtgacta agtcttggtc ggctctcaac ggaaactata tcccagcctt
    23341 tttaggtgct gctcttctct actttgccct atgcttccct gttgcccagt ttggtcgcaa
    23401 gatggagcaa gtcaataaaa aagcctattc actttaggag gttactatgg aatctatttt
    23461 agaaatttta accccagata acctagtctt tatctttaaa ggatttggct tgaccctcta
    23521 tatttctctg attgccatca tcctctctac tatcatcggt accgtgcttg ccgtcatgcg
    23581 aaatggaaaa aatcctatct tacgcattat ttccagtatt tatatcgagt ttgtgcgcaa
    23641 cgttcccaac cttctctgga tttttactat ctttttggtg ttcaaaatga agtccacacc
    23701 agcaggtatt acagccttta ctctctttac atcagcagcc ttggctgaga ttattcgagg
    23761 cggtctcaat gccgtagaca agggacaata cgaagcagga atgtcacaag gcttcacctc
    23821 agcccaaatc ctctactaca tcattctccc acaagccatc cgcaaaatgc taccagccat
    23881 catttctcag tttgttaccg tgattaagga taccagtctc ctctactctg ttatcgccct
    23941 acaagaactc tttggagcca gccaaattct catgggccgt tatttcgaac cagagcaggt
    24001 cttcagtctt tacatcctga ttgccctcat ctacttcagc tttaacctag caatttctaa
    24061 cctgtctcat atgctagcaa aacgttggca acaagctgca gaataacaaa ttagctctct
    24121 agttcattgg agagtttttt gatgatagta gatatttata gacctcaatt tgacaccata
    24181 cattttctat gataaaatgt aacaaattta tttacaacaa atcgaaatct aaatgaaatg
    24241 gaattttcta tgaaatcaat caaaggacta ctctttatca tagctagttt tatcttgact
    24301 cttttgactt ggatgaacac ttctccccaa ttcatgattc caggactagc tttaacaagc
    24361 ctatctctga cttttatcct agccactcgt ctcccactac tagaaagctg gtttcacggt
    24421 ttggagaagg tctacaccgt ccacaaattc acagcctttc tctcaatcat cctactaatc
    24481 tttcataact ttagtatggg cggtttgtgg ggctctcgct tagctgctca gtttggcaat
    24541 cttgccatct atatctttgc cagcatcatc cttgtcgcct atttaggcaa atacatccaa
    24601 tacgaagctt ggcgatggat tcaccgcctg gtttacctag cctatatttt aggactcttt
    24661 cacatctaca tgataatggg caatcgtctc cttacattta atcttctaag ttttcttgtt
    24721 ggtagctatg cccttttagg cttactagct ggtttttata tcatttttct atatcaaaag
    24781 atttccttcc cctatctagg gaaaattacc catctcaaac gcttaaatca cgatactaga
    24841 gaaattcaaa tccatcttag cagacctttc aactatcaat caggacaatt tgcctttcta
    24901 aagattttcc aagaaggctt tgaaagtgct ccgcatccct tttctatctc aggaggtcat
    24961 ggtcaaactc tttactttac tgttaaaaat tcaggcgacc ataccaagaa tatctatgat
    25021 aatcttcaag ccggcagcaa agtaacccta gacagagctt acggacacat gatcatagaa
    25081 gaaggacgag aaaatcaggt ttggattgct ggaggtattg ggatcacccc cttcatctct
    25141 tacatccgtg aacatcctat tttagataaa caggttcact tctactatag cttccgtgga
    25201 gatgaaaatg cagtctacct agatttactc cgtaactatg ctcagaaaaa tcctaatttt
    25261 gaactccatc taatcgacag tacgaaagac ggctatctta attttgaaca aaaagaagtg
    25321 cccgaacatg caaccgtcta tatgtgtggt cctatttcta tgatgaaggc acttgccaaa
    25381 cagattaaga aacaaaatcc aaaaacagag cttatttacg aaggattcaa gttcaaataa
    25441 gtaatcatac tctcctggga tttcccagga gagtttttta tagccaaatg aaataagacc
    25501 ggaacgatgg aattttggca ttcaaatcaa ttgataagaa tattttatag tggagtgaaa
    25561 taggatacga acaaattgat taggaaaatc aaatgaattt atagaaatct tttagcagtt
    25621 atgttgtcct gttctagttt caaaacgcta tagaaacagc attgtgctag tctagattca
    25681 gtttactata ctaaaacgag tagcttgaaa tcaaaaaacc caccctcaca ggcaggtttt
    25741 atctgtatta ttcagctaga ttatgcttta ccttctgaac cgaatacgtc gatacgttct
    25801 tcaaccgatg cttggatagc ttttacaccg tcagccaaga atttacgtgg gtcgaagagt
    25861 tttttcttgt cgtattctgc ttcgtttgct tcgtagtcac gagcaaattt acgagttgcg
    25921 ttagcgaatg cgatttggca ttctgtgtta acgttaactt tggcaacacc aagtttgata
    25981 gctgcttgga tttgctcatc aggaatacct gatccaccgt gcaatacgat tgggaatcct
    26041 ggaagagctt ctgtcaattt ttgcaagtgg tcaaggtcaa gaccttccca gtttactggg
    26101 taagggccgt ggatgttacc gataccagct gccaagaagt cgataccagt ttcaaccatt
    26161 gctttagcgt cttcgattgg agccaattca cctttaccga tgattccgtc ttcttcacca
    26221 ccgatagtac caacttcagc ttctactgag atacctttag cgtgtgcttt ttcaacaact
    26281 tctttagcca atttaaggtt ttcttcaact ggaaggtgtg aaccgtcaaa catgattgaa
    26341 gtataaccaa cttcgataca ctcaagtgca tcttcgtagt gaccgtggtc aaggtggata
    26401 gctactggta cagtgatacc cattgattca acaaggttag cgatcaagtt gcgagcaact
    26461 ttgtaaccac ccatgtattt agcagcaccc attgaagttt ggatcaaaac tggagctttt
    26521 ttagcttctg ctgcgcgcaa gatagcttga gtccactcaa ggttgtttgt gttaaatcca
    26581 ccaactgcat aaccgttgtc acgggctgct tggacaaatt tttctgctga aacgattgcc
    26641 attttatcag gcctcctgta tatttttatg ggtcatccca tttacattgt tcattttatc
    26701 actttttgcc aaaaaaatct agtttttccc gcagtttcga ttgattttct tctaactcca
    26761 tctatgtaaa ccctttctct ccctagtctt ggacgacttt tggaaaatct ataaagaagg
    26821 ttaaacgatt ctcctccatc tcgaaacgat aagctaattt ttcatgttct aatagactct
    26881 taaccacaaa gagccccata ccagacccct tgaccttgcg actggcattg tcagaaaaag
    26941 actgggctag tttttcttgt tcctctgagc tacagctatt ttcgataaaa agttctcctt
    27001 ctctttctcc aattcgaact aagccacctg gaacagagtg cttaatggca ttgctgatga
    27061 gattagaaag aatcaacttc ataactgatg ggtttagata agcctgctga tgggtcaaac
    27121 tattgtctat ctggagctct ctttccttgg ctagcaaggc ataatctttg accagatttt
    27181 gcgtcatctg gaggaggtca attgtttccc tatcatctcg caattcctgc acagaagaga
    27241 gggaaagtat ctgcagaaca tggtgattga gttcatccac aatccccaag gcaactccca
    27301 gatactggtc tctatcctta taacgaccga tattctctct catattttcg attaggattt
    27361 tcaaactagc cagcggtgtt ttcaattcat gagaagctcc tcgtaggaat tcgaccttca
    27421 tcttctccag ctggagaatg gcttcattct tttcatgcaa gtccgcaata acagtcaaga
    27481 gatgctggta gaggctattg atttgttcct tgagattacc tatctcatcc ttagaatcca
    27541 cgcgcaatcg cacttgggaa tccaggtcca tcatccgacg ggtcacccgc ttgatttcca
    27601 agatcggtgc aacaatagtc cgagcgtaga tgtaggccac caagagggaa atcagaaagg
    27661 aggccagcaa ggtataggga agaaactgga gactgatttg ctccgcttcc ttttgtaaat
    27721 ccatggaagc tagaaactgg agaatcatag tagcaccgtc ttgcgttttc acctcgcgct
    27781 cctcaataaa gagagaggtt gtctggcggt ctgtgtccag aggaagactg tccttgactt
    27841 ctaacttgtc ctcggtcatc tcacctttga cggtcccctt gatatcacta gtctgggaat
    27901 acaagtctaa cacttgctcg atactctgcc tatctttccc ttctagggac tgggcaatgg
    27961 ctgttgcctt ttgaccaatg gtttcctgac gatgactcag ataagtcgaa ggaaaaagaa
    28021 aataaatagc taaatgaagg cagataacca gaacactaaa tatcgagaag gtatagataa
    28081 atatctttgc aaataaacct gttcgtttca ttttcgctcc aatttataac caacattgcg
    28141 cacagtgagg atacaatcca agtctagctt tttccgcaat tccttgatat aaacatcaat
    28201 aacacggtca aagggaacct catctgtcgc tttccagacg gcatcgataa tctgagatcg
    28261 agtcaaggcc cggccttcat ttttcactag atagtccaga atttccaact ctttggcatt
    28321 gataggcact tcttgacctg cgatgcttgc actgtagctt tcaaagtcca ccttggtatc
    28381 cttgtaagaa aagattcgtc ctgtatcgta gtagcgcttg aaaatcgcgt ccaccctcac
    28441 ttttaaaagg gagagggaga aaggtttttc cagatagcca tctgccaaag aggcaaaggc
    28501 actcatcttg tattcctcat cctgaaaagc tgtcaacatc aagacaggaa cctgactggt
    28561 tttacgaatc tcagctagga cttctaagcc gttgagcttg ggcatctgga tatccagtaa
    28621 aaccagggcc acctcatagc tagaaaattg ctccagagct tcctgaccgt ccgctgcctc
    28681 aatagtttca tagccacaat ccgtcaaata atcactgacc ccctcacgga tcatctcttc
    28741 atcttctaca attaaaattt tcatacttta actgctctct attttttatt tttcttagaa
    28801 taaataccta ctctattttc tattatagtc tcttgctggc cttttgtctg taagcaactg
    28861 accactagat aaaacgttgt gaaatccttt ctcataaatt ccataacttt agtatattat
    28921 atttaagcac taaagtacaa agaaagcaac tgaaagcaat gattttcacc actgctttcg
    28981 gatttatttt gaattgttaa atagccattc ctatccacta ttcttgaata gaaacacaag
    29041 atgcaatctt tattctagac ccattttttc aaatttattc accatccagc aagagctctt
    29101 ttggttgttt tctaaggaga ttgcttgaag caagcaccat aacgagaacc actagaacca
    29161 aggcaaggac aaaaatgatg ataaagtctg atgtctgaat ggaaatgtct aggctcgaca
    29221 aggtcttgct aaagccatct acttctgcac caccaccaag gttagaggct tgagccgcct
    29281 tactagcctg tttggcaaca cctgaagtca cattggcaag gacagtgttt ccaattgcac
    29341 gggcagtgta attagctagg aagtaagcag aaactagagc agggatagca atcaagatag
    29401 attcggtgat gaattgaccc aagatacttg cctgcttgag gccgatagag aggagaattc
    29461 ccacttcctt gcgacgggcg ttgatccaaa ggctgagcaa gagggcaagg aggagaactg
    29521 agaagctcaa gctaccccag aagaggaggt tggccatctt gtacatacca gagatagatt
    29581 gctcaagagc tgggtagtta gaggagctct tgacgagtgt gtagctcttc cagttgatac
    29641 cactgatgcc attcaactct ttcataacat catccaagtt cttgtctgct gttacaaaga
    29701 aggttgcgtc cccataaatg gctgtgtctt ctgtgtatcc ataaagtttt gcagcagtgt
    29761 gaatgtctgt aatagctgtg ttttcgtaaa gttcttgtga gtaggttact gctgacttat
    29821 tatgaccatc aaagagtccc ttgattgtca cttcaactgt ttccttggct cctttttcat
    29881 tatctgcatc gtagatatta gagtccagtt taaccttatc ccctactttc cagccgtgtt
    29941 tggctgccaa gtccttgtgc aagaggattt tatccttgtc gtcgttggtt aagtgctctc
    30001 cttcgactag tttataagaa ccagagacaa acttgtcttc tttagaggag tcattgacac
    30061 ctgtaatcat caagctactt ccaaaacgtt tggcacgatc agcagtgaga ttcttcttgg
    30121 tttctggcgt ttcaatcagg tcatatccag tcaaatctcc gatagcgttg atacgtttga
    30181 cataagactc aatggccttg ttttcggtga tttttttgat gtcttcaccc ttgatattcc
    30241 cagcaccgcg aggcgttcct tggttgacgc gacgattgat ttgcatggag aagctattgg
    30301 tgatattttt aaaggtctcc tgagaagcct tggcagtagc tcccttgatt gacaagccga
    30361 ccaaactcaa gctcgccatg aggagaataa tcaggaagat gacaatcgat ttgaaaaact
    30421 tccttgtaac ataggcaaat gcgttgtgta acatagattc cctttctaga ttttgtttta
    30481 atcattctat caaaataagc tcaaattatt tactagtatt gcgcgtttca gtcagtttct
    30541 tatcctttaa ttcaagtgta atatctgacg cttgtgccac ttctttactg tgagttacga
    30601 caatcacaca tttacctgtt ttctgggcaa gtgatttgag tagttcgaca atatctccag
    30661 cagttttagg atccagattt cctgttggct catcagctag aataactgga gcttctgaga
    30721 ccaaactgcg agcaatggca acacgttgct gttgaccacc tgataactgg agaacattcc
    30781 gcttgatctg gctttcatcc aaaccaagct caagaagtgt attcttgctt gcctttttgt
    30841 tgaccaattg gatattttcc agcggagaaa gataatctat caagttataa ttttgaaaga
    30901 ccagggaaat atggtgcatg cgatggtaag aatagccctt cttacgaata tcctctcctt
    30961 gaaaaaggat agaaccttca acaggactat ctagaccagc aagtagggac aagagtgtgg
    31021 attttcctgc tcctgactcc ccaataatac tgtaaaattt tccgggttca aaattataat
    31081 tgatctgata taggactgct tcagcagtat tcttataacg gtaggtaaca tcttgtaatt
    31141 gtaataaagt catgatttct ccttcttaac taatagatga taaaatttct ttcggtgatt
    31201 ttctaaataa gaataggaaa caaagggcta cagataagca actaagcaga actagaaaaa
    31261 cataggattc tgcaaaagat aagatgctag ttgataaact gcttgctttg gctagtgtat
    31321 cttgtaagct tgcctgatct ccacttgcta gtagagtttg gagtaggtaa gttgtgattg
    31381 cgtttcctgc aacaaatgct ggaagcaaag ctccaagaga taccaaaact acctctaaac
    31441 agaattgtag gaagatcgag ctcttgcctt ttccaagtgc aagtaaaatc cccacttcat
    31501 agacccgttc tctcaaccag agagacaaaa ccagaattaa ggctccagct cctgctatca
    31561 acatcccata aaggaagatg gtcaggaagg tttggaaagt tgcaactgag tctttgattt
    31621 gttcaaaagc cttgttttcc ttttcgactt ggtagccttg attttccaag gccaagtttt
    31681 ctacctgctt catgagtccg tccatttcct taggattttc tacatagaag cgtgctgcac
    31741 tgacttgagc ttcactattg cccaaaaggg tttggctact ttcatagtct gtaaagactt
    31801 gattttcact gaagtcagaa gacaagcctg tgaatttctc ttgtttttta ccagaaaaga
    31861 tgccaataat ctcaaactct actgtttgtc cttttccaga ttcagactga ccagcatcca
    31921 agccaatctt gtcatgaagt gaaagaccgt tcttcttagc caattcttcg tggataagga
    31981 ttttcttgga atcccctttt tgaaggtgtc gcccttcttt tagattgaaa gccgaactgg
    32041 taaaggttac atccttggat gaatcctcaa gagccgttaa gctaaccaag ttattgtctg
    32101 cagctgataa atcatcacgc tccacgctct gctcgccagt cactgcttcc ttgtctttta
    32161 gttttgcgac cgtctcaagt tcaggagaga cattttccag ccccttaatc ttgcttacag
    32221 atgctaggtc tgacaacttg aatgtctgac cattctctat cttcttaata gaaaaagatg
    32281 tattgagtga tttataaaga ttgctttcta ctgttttgtt ggacttcatc agagtcaaac
    32341 aggctgaaat tccggccaat aagaccaata aaatcagaaa taaaataaaa cttctcagtc
    32401 gctttctgct gacataagcc caagatcttt ggattggatt catttgtcac ctccatattt
    32461 gtaagactat tataaaaccc aaatatgaaa tgtttatgaa atacgaaaaa aaaa
//
LOCUS       DAVLHB010000021        31852 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLHB010000021 DAVLHB010000000
VERSION     DAVLHB010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.021"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            470..1513
                     /locus_tag="VXE36_001095"
     CDS             470..1513
                     /locus_tag="VXE36_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0779413.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1680..3767
                     /gene="topA"
                     /locus_tag="VXE36_001096"
     CDS             1680..3767
                     /gene="topA"
                     /locus_tag="VXE36_001096"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0779414.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3873..4232
                     /locus_tag="VXE36_001097"
     CDS             3873..4232
                     /locus_tag="VXE36_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0779415.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4325..4957
                     /locus_tag="VXE36_001098"
     CDS             4325..4957
                     /locus_tag="VXE36_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0779416.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5001..5657
                     /locus_tag="VXE36_001099"
     CDS             5001..5657
                     /locus_tag="VXE36_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0779417.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLKLIEKSWNLTSKK
                     "
     gene            5676..6770
                     /locus_tag="VXE36_001100"
     CDS             5676..6770
                     /locus_tag="VXE36_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0779418.1"
                     /translation="MNFQLAKYSLLKKFSENIEFTTSEEYGAIFKCLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6782..7819
                     /gene="leuB"
                     /locus_tag="VXE36_001101"
     CDS             6782..7819
                     /gene="leuB"
                     /locus_tag="VXE36_001101"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0779419.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7816..8085
                     /locus_tag="VXE36_001102"
     CDS             7816..8085
                     /locus_tag="VXE36_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0779420.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8089..8448
                     /locus_tag="VXE36_001103"
     CDS             8089..8448
                     /locus_tag="VXE36_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0779421.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8610..9180
                     /locus_tag="VXE36_001104"
                     /pseudo
     CDS             8610..9180
                     /locus_tag="VXE36_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9504..11435
                     /locus_tag="VXE36_001105"
     CDS             9504..11435
                     /locus_tag="VXE36_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0779422.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11422..12738
                     /locus_tag="VXE36_001106"
     CDS             11422..12738
                     /locus_tag="VXE36_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0779423.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLILDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            12913..13899
                     /locus_tag="VXE36_001107"
     CDS             12913..13899
                     /locus_tag="VXE36_001107"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0779424.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13963..14034
                     /locus_tag="VXE36_001108"
     tRNA            13963..14034
                     /locus_tag="VXE36_001108"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13996..13998,aa:Arg,seq:ccg)
     gene            14217..14915
                     /locus_tag="VXE36_001109"
     CDS             14217..14915
                     /locus_tag="VXE36_001109"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0779425.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14906..18445
                     /gene="smc"
                     /locus_tag="VXE36_001110"
     CDS             14906..18445
                     /gene="smc"
                     /locus_tag="VXE36_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0779426.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFNNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDEMARLTESLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDRYEEVHNRLDFLNSQRDDILSAKNLLLETITKMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18442..19236
                     /locus_tag="VXE36_001111"
     CDS             18442..19236
                     /locus_tag="VXE36_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0779427.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSREFYLATFEKLKKSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            19236..20054
                     /locus_tag="VXE36_001112"
     CDS             19236..20054
                     /locus_tag="VXE36_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0779428.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            20058..21347
                     /gene="ftsY"
                     /locus_tag="VXE36_001113"
     CDS             20058..21347
                     /gene="ftsY"
                     /locus_tag="VXE36_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0779429.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDTEPALTEAEEAS
                     QEEAEVEIVEQAVLQEVENQDTVEESQDSEPTVVVSQEEVEELPNSEEVLEEENPEHE
                     RTVEENNSEVLEAERPQVEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGNYDES
                     IHFQDGLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVSEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21393..22880)
                     /locus_tag="VXE36_001114"
     CDS             complement(21393..22880)
                     /locus_tag="VXE36_001114"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0779430.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(23029..23769)
                     /locus_tag="VXE36_001115"
     CDS             complement(23029..23769)
                     /locus_tag="VXE36_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0779431.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23769..25934)
                     /locus_tag="VXE36_001116"
     CDS             complement(23769..25934)
                     /locus_tag="VXE36_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0779432.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     RKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            26107..27060
                     /locus_tag="VXE36_001117"
     CDS             26107..27060
                     /locus_tag="VXE36_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0779433.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVTMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            27137..29125
                     /gene="uvrB"
                     /locus_tag="VXE36_001118"
     CDS             27137..29125
                     /gene="uvrB"
                     /locus_tag="VXE36_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0779434.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            29135..29698
                     /locus_tag="VXE36_001119"
     CDS             29135..29698
                     /locus_tag="VXE36_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779435.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29664..30173
                     /locus_tag="VXE36_001120"
     CDS             29664..30173
                     /locus_tag="VXE36_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779436.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKTALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            30226..30693
                     /locus_tag="VXE36_001121"
                     /pseudo
     CDS             30226..30693
                     /locus_tag="VXE36_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
     gene            complement(30690..31205)
                     /locus_tag="VXE36_001122"
     CDS             complement(30690..31205)
                     /locus_tag="VXE36_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0779437.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYVYKQVDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGRVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTEGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31217..31744)
                     /locus_tag="VXE36_001123"
     CDS             complement(31217..31744)
                     /locus_tag="VXE36_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0779438.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHIFFGTLGALYLQKFPDTL
                     DKPKSSLIFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT         9866 a         5656 c         7073 g         9257 t
ORIGIN      
        1 attcaataca ctataattta gtgtaattga gaaaggagaa atgattgtga ttgatgttgg
       61 ctaggttatg ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa aaataaattc
      121 ttcaaaagta gagattacaa ggcttgttta agaaagaatt caaagacctt gacaaataaa
      181 aataaaatgg ttattataag aaatggtcta aaatagatga tgatactttt cgaaaatctt
      241 tttacgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta gcttccgagt
      301 ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat ttgagtcagg
      361 atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta ctaaagtatt
      421 gagtttgtta ggattttagc gactagttag ctgggaaagg aagatatttg tgacaaataa
      481 taaactgtat tcgttgatag aatttagaaa taagatatat gaagaattag aactttccag
      541 aagtgattta gcgattttac tatgtgccat gcttatcgcc tctatcggat taaatatgga
      601 ttcgactccc gtgattattg gagccatgtt aatctctcct ttgatgacac ctattctggg
      661 agtggggctc tctctagcta tatttgattt taaattgtta agaaaatctt ttaaaatatt
      721 agctattcaa attcttgcca gtttaatagc ttcaacactt tatttttatc tttctcccat
      781 ttcgtatgct agttcggaaa ttgttgctag aacctctccg actatttggg atgttctcat
      841 tgcttttgta ggagggatag caggtattat tggtgctagg aaaaaagaga ccaataatat
      901 tgttcctggt gttgctattg caaccgcctt gatgcctcct ctttgtacag taggttatgc
      961 tattgcttct gctaatctaa aatttatcat aggctcctct tacctattcc tcatcaattg
     1021 tagctttatt gtcattgcga cttatatagg tgttaggttg atgatggtta agaaacatta
     1081 ttttaaagat aatgaagaag actctaaaat gcgtaggatt ttgcttctag ttgctgtttt
     1141 gctgatgatt ccgagtttca tctctgcaac gactttagtg agagaaacgt tgaaaaaaga
     1201 gtcccttaag aaatttatat cagagcagtt tcaggggtat aatattttga aaaaaaccta
     1261 ttctaaaaag actcataccc taaagctaac catttcagga aattatttga cagaagaaga
     1321 actcgatatg atttcaagta agagaggtga ctatggttta agtgatgttt ctgttcaagt
     1381 ttcacaattg tctgattcag aacaacttag taaggaagag ctggtggagc atttcttcca
     1441 gtatatcaag gataaggaag caaaagaaaa ggagaaagcc aataaatttg atacagagtc
     1501 tgaggagcaa taatttcttg agaatagctg gtttctctcg tgagtcttct atgtatatca
     1561 aaggaagact gaggttttaa gtataaaact tttcttctat tatagtagct aagtcttgac
     1621 agggttcaaa aaatggttta cactttataa agtttattac tttgaaaagg tgtgatactg
     1681 tggctacggc aacaaaaaag aaaaaatcaa cagtaaaaaa aaatctagtc atcgtggagt
     1741 cgcctgctaa ggccaagacg attgaaaaat atctaggcag aaactacaag gttttagcca
     1801 gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt gaaaataatt
     1861 atgaaccgca atatatcaat atccgaggaa aaggccctct tatcaatgac ttgaaaaaag
     1921 aagctaaaaa agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa ggagaagcga
     1981 tttcttggca tttggcccat attctcaact tggatgaaaa tgatgccaac cgtgtggtct
     2041 tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa agaacctcgt aagatcgata
     2101 tggacttggt cgatgcccaa caagctcgtc ggatcttgga tcgcttggta gggtattcga
     2161 tttcgcctat tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc gttcagtcca
     2221 ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa tgccttccag ccagaagaat
     2281 actggacagt tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct tccttctatg
     2341 gagtagatgg taaaaagatg aaactgacca gcaatgacga agtcaaggaa gtcttgtctc
     2401 gtctgacgag taaagacttt tcagtagatc aggtggataa gaaagagcgc aagcgcaatg
     2461 ctcctttacc ctataccact tcatctatgc agatggatgc tgccaataaa atcaatttcc
     2521 gtactcgaaa aaccatgatg gttgcccaac agctctatga aggaattaat atcggttctg
     2581 gtgttcaagg tttgattacc tatatgcgta ccgattcgac tcgtatcagt cctgtagcgc
     2641 aaaatgaggc ggcaagcttc attacggatc gttttggtag taagtattct aagcacggta
     2701 gcaaggtcaa aaacgcgtca ggtgctcagg atgcccatga ggctattcgt ccgtcaagtg
     2761 tctttaatac accagaaagc atcgctaagt atctggacaa ggatcagctc aagctatata
     2821 cccttatctg gaatcgtttt gtggctagcc agatgacagc ggccgttttt gataccatgg
     2881 ctgttaaatt gtctcaaaaa ggggttcaat ttgctgccaa tggtagtcag gttaagtttg
     2941 atggttatct tgccatttat aatgattctg acaagaataa gatgttaccg gacatggttg
     3001 ttggagatgt ggtcaaacag gtcaatagca aaccagagca acatttcacc caaccgcctg
     3061 cccgttattc tgaagcaaca ctgattaaaa ccttagagga aaatggagtt ggacgtccat
     3121 caacctacgc gccaaccatt gaaaccattc agaaacgtta ttatgttcgc ctggcagcca
     3181 aacgttttga accgacagag ttgggagaaa ttgtcaataa gctcatcgtt gaatatttcc
     3241 cagatatcgt aaacgtgacc ttcacagctg aaatggaagg taaactggat gatgtcgaag
     3301 ttggaaaaga gcagtggcga cgggtcattg atgcctttta caaaccattc tctaaagaag
     3361 ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa ggatgaacca gctggatttg
     3421 actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt aaattctacg
     3481 cttgtagcaa tttcccagat tgccgtcata cccaagcaat cgtgaaagag attggtgttg
     3541 agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt aatcgcctct
     3601 tctatggttg caatcgctat ccagaatgtg aatttacctc ttgggacaag cctgttggtc
     3661 gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa agtccgtggt ggtggcaagc
     3721 aggttgtttg tagcaaaggc gactacgagg aagaaaagat taaataagag gaggggcccg
     3781 aaagtaaatt tcaggctcct tttggttaga acttgacaaa atacatcatt ttatgcgaaa
     3841 ctagaagaag attattttaa ctaggagaag ttatgcgtct tatctatctg ataattggtt
     3901 ttttatcact ggccttggct attgttgggg ttgttttacc cttgttgccg acaacgcctt
     3961 tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgtttcgaa gactggcttt
     4021 atcataccaa gctctatcaa acatatgtag ctgattttcg cgagactaag tctattacgc
     4081 gtgaacgaaa gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt tctatttatt
     4141 ttgcacctct tttaccagtc aaaatcggtc tgggtgcttt gaccatcttt atcacttatt
     4201 atcttttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt gccttgataa
     4261 aattgaaagc atattcataa taatatgata taataaattt gaagtaatat tcaaggagaa
     4321 tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag cgatgcaggc
     4381 tggagctcgt cggattgaac tctgtgataa tctagcagtc ggtgggacaa cacccagcta
     4441 tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca tcatgaccat
     4501 gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta tcatgctaga
     4561 agacattcgt ttgactgctc aggctggaag tcaaggggtt gtatttggag ctttaactgc
     4621 tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa aaggaatgga
     4681 aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg aagctattga
     4741 ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt ctggcgactc
     4801 cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag gtaaaattga
     4861 aattctacca ggtgggggga ttgaccttga aaaccgtcaa acctttatcg accaggtggg
     4921 ggtaacacaa ttgcatggta ctaaggttgt tttttaaaaa atagaaagga actgctagct
     4981 tttggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt aatcaagaaa
     5041 aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt tgccagattt
     5101 tgcaaggtga ctttgtcatg actgtgtcca tcactgctga taatgtgaac tttcaagtct
     5161 ttgaccaaga gactggtgac ctctatcctc atgttcatat ggaaagcatg aggggaagtt
     5221 ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg aaggcttgtt
     5281 ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa gttcaggaaa
     5341 agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct gtattgcgcc
     5401 atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat aagctggaaa
     5461 agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta gctaatttgc
     5521 tttcacaaaa ggggatttat ccagccttcc atatgagcaa gcgctactgg attagtgtgt
     5581 cccttgatga tactttatca gatgaagaag tactgaaatt gatagaaaaa agttggaact
     5641 taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaatta gctaaatatt
     5701 ctttactgaa gaaattttca gaaaatatag aatttaccac atcagaggaa tatggtgcca
     5761 tcttcaaatg cctgattgag aatgtcaaga cggatcgtca gatcatctat tcgcctcact
     5821 gtcatgatga ccttggaatg gcagtggcaa atagccttgc tgctgtcaag aatggtgcag
     5881 gacgtgttga agggactatc aatggtatta gggagcgagc tggaaatgct gctttggaag
     5941 aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc agtattgtcc
     6001 taaatgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt ccagttccta
     6061 aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt caccaagatg
     6121 gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt ggtgttaaga
     6181 ttccgcttgg aaaattatct ggtcgccatg cttttgttga gaaactgaga gaattggccc
     6241 tagattttac agaagaggat atcaaaccac tctttgctaa gttcaaggca ctggtcgata
     6301 agaagcaaga aatcacagat gcagatattc gagctttggt agctggaacc atggttgaaa
     6361 atccagaagg tttccacttt gatgatttac aacttcaaac tcatgcagat aatgacattg
     6421 aagcgctcgt tagcctagcc aatatggatg gtgagaaagt cgaatttaat gcgacagggc
     6481 aaggttccgt tgaagcaatc tttaacgcta tcgataagtt ctttaaccaa tctgttcgtt
     6541 tggtgtccta cactatcaat gcggtaacag atggaatcga tgcccaggat cgggttttgg
     6601 tcactgttga aaacagagat acagaaacca tctttaatgc agcagggctt gattttgatg
     6661 tgttgaaggc ttctgctatt gcctatataa acgctaatac ctttgttcaa aaagagaatg
     6721 caggtgagat gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa aggagaaggc
     6781 tatggcaaag aaaatagtag ctctagtagg agacggaatt ggcccagaaa tcatggaggc
     6841 tggtttagaa gttctggagg ctctagctga aaaaacaggt tttgactatg agattgacag
     6901 acgaccgttc ggaggtgcag atattgatgc agcaggccct cccttacctg atgaaaccct
     6961 taaggcaagt agggaagcag atgctatcct actagcagct atcggtagtc ctcagtatga
     7021 tggagcagcg gttcgccctg aacaaggcct gatggctctc cgtaaggaac tcaatcttta
     7081 cgctaatatt cgtcctgtaa aaatctttga cagtctcaag tatttgtcac cactcaaacc
     7141 ggaacgaatt tctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg agatttactt
     7201 tggagatcat attcttgaag agcgcaaagc gcgtgatatc aacgactata gctatgagga
     7261 agtggagcgg attattcgca aagcctttga aattgcaaga aatcgcagaa aaatcgttac
     7321 tagtatcgat aagcaaaatg ttctagcgac ctcaaaactc tggcggaagg tagctgagga
     7381 agtcgcacag gatttcccag atgtaacctt ggaacatcag ctggtagact cagctgctat
     7441 gcttatgatt accaatcctg ctaagtttga tgttattgta acggagaatc tttttggaga
     7501 tattttatct gatgaatcaa gcgtcttatc tggtacactt ggggttatgc catcagccag
     7561 tcattctgaa aatggaccaa gtctctatga acctattcac ggttcagcac ctgatattgc
     7621 aggtcaagga attgccaatc ctatttccat gattttatca gttgtcatga tgttgagaga
     7681 tagtttcgga cgttatgagg atgcagagcg tatcaaacgt gctgttgaga caagtctggc
     7741 ggcaggaatt ttaacgagag atataggagg tcaggcttca acaaaggaaa tgacggaagc
     7801 tattattgca aggttatgaa gttagacgaa aaaattactc tagtcctttt gatttggaat
     7861 gtcatcattt tcttgattta tggcattgac aaattcaagg caagaagaag agcttggcgc
     7921 atccaagaga aaatcttact cattttagcc cttacttgtg gtggttttgg ggcctggtta
     7981 gctggaatca cttttcacca caagactcga aaatggtact ttaaaacagt ttggtttctt
     8041 gggatggtga ctacactagt agccttatat tttatttgga ggtaatggat ggcagggtct
     8101 tcgagggaac acgctgcttg ggctctagcg aactatggtt ttaaggtcgt gattgcagga
     8161 actttcggtg acattcatta caataatgaa ctcaataatg gcctgttgcc aatcgttcag
     8221 cctagagagg ttagagagaa actagcccag ctaaaaccaa ccgaccatgt aactgtggac
     8281 ttggaacaac aaaaaatcat ctcaccagtt gaagaattca ccttcgagat agatagcgag
     8341 tggaaacata aactcctaaa tagtttggat gatatcggta ttaccttgca gtatgaagag
     8401 ttgattgctg cttatgaaaa acaacgacca gcctactggc aggattagaa aaaatagaaa
     8461 aggaaatata gtaaactgaa ataagatgta aacaaatgaa ttagagctta acatccattt
     8521 ctagcaattt tttagaaact acagtggact attctggatt caacacatta taaaattatg
     8581 acaaaacaca ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga tgtatcgttt
     8641 gccctactaa agttggttac attatcatga ccagtgacaa ggcaggactt gagcgtaagt
     8701 tcgcagccaa agaacgtaag cgtaacaaac caggtgttgt tctctgcggt agcatggatg
     8761 aacttcgcgc tttagcgcaa ctcaacccag aaattgaagc attctactaa aaacattggg
     8821 atgaagatat tcttcttggt tgtatccttc cttggaaacc agaagcctct gaaaaactca
     8881 aagcatacgg ggatggccgt gaagaactta tgactgatgt acgtggtact agctgttttg
     8941 ttatcaagtt tggaaaagca ggtgaacaat tggctgccaa gctttgggaa gaaggtaaaa
     9001 tggtctacgc ctcatctgct tcaatgacaa aacgattgaa actcgctatg agagcaaggt
     9061 gtaatggtgt ctatggtcga taaggacggc aaactcatcc cagaacaagg aggagcacgt
     9121 tcaacttcac cagcaccagt tgtgatccgt aaagggcttg acattgatat agtaaaatga
     9181 agtaagagca ggacaaatta atcaggacag tcaaatcgat ttctaacaat gttttagaag
     9241 tagaggtgta ctattctagt ttcaatccac tataaaatca tgatgcacct gtcagatact
     9301 tttaactcat gggactgccg tcagggtgag tattattaag ataaaaaaag aagtctagtg
     9361 ttatgagata ttaaagctcc taacactggg cttttgttta gaatttcttt tctttttcta
     9421 taggatatga tattctatgt agaaaatata tgttaataag taatgccaat atttaaacat
     9481 cattagtaaa aggagttaga ttgatgaata aaagaaaagt tagtttagaa gatttttata
     9541 aatggtatag tctaaataaa gaagagttat taaataaggc aactgttggt gaaaagttta
     9601 atgataaatt aaaagaagag tttctccagg aatggccttt ggataggatt ttaacaatgt
     9661 caatcgatga atatgtaata ggaaagggac agcaaaataa gtctttatgc tacgctcttg
     9721 agaagggaaa atacaaaaat ctatttcttg gaatttctgg tggctcagct tcaaaatttg
     9781 gtatttattg gaataaaaaa acaaacaaat ataaagatca agctaataat gagatttcag
     9841 agttggatca gcgattttca aaattaaaat cagatttgta tgaaattatc aaagaaggta
     9901 ttcgttttaa ctttgaaaat cctatttttg atatgaaaag atcaacaaat gaatttattg
     9961 gtcgttctgc tatggtgaca aaattacttt gtatctattc tgggggagat cctttctttg
    10021 gtgtaaatat taatagtcag aaagaatttt ggaaccactt tgtttctcag acaaatcaag
    10081 gtggacctta tctgcaaaat cataaaataa ttgaactggt gtccaaaact tatcctgagt
    10141 tggagccatc gaaattagga actatgcttt ttgagtattc taagcttttt atggaaaata
    10201 aggaagacaa tagtacaatg gattcatcaa acaattttcg tcatcaatta actcaatctc
    10261 tattaaagtc tccaaacctt atccttcgtg gtgctcctgg cacaggaaag acttatcttg
    10321 ctaaagaaat tgccaaagaa ttaacggatg gcaacgaaga ccaaatcgga tttgtacaat
    10381 ttcacccatc ctatgattat acggattttg tagaaggttt aagaccagta tcaaatgggg
    10441 atggagctat tgagtttagg ctacaggacg gtatttttaa agatttttgt cagaaagcaa
    10501 aagaaaccca attgattgga ggacaagata attttgatga ggcttgggat tcttacttag
    10561 aatatataaa tgttgctgaa gaaaaagaat atataacaaa aacatcttac ttatctgtta
    10621 atagtagaca aaatttgtca gtaaattatg atagtggtgt tccaggatgg tcactaccta
    10681 gcaaatatgt ttacgagttg tataaagata aaaattataa taagcaagaa tactacaaaa
    10741 gtggtggaaa aactgtccta gaaacattga gaaagagatt tggtttgaaa gactatgttt
    10801 ccccaacaga aattgatact gataagaaat tcgtcttcat catcgatgaa atcaatcgtg
    10861 gggagatttc taagattttt ggcgaactct ttttctctat cgaccctggc tatcgtggtg
    10921 aaaaaggaag tgtttctacc caatatgcaa atctacacga aactgatgaa aagttctata
    10981 tccccgaaaa tgtttacatc atcggaacta tgaatgatat tgatcgttca gtggatacct
    11041 ttgattttgc tatgcgtcgt cgttttcgtt ttgttgaagt tactgccgag ggtcaagttg
    11101 gcatgttgga taaagagctg aatatccatg cagaagaagc aaaaattcgt ctaagaaact
    11161 tgaacgctgc tatcgaaaat gttcaggaat taaacagtca ttatcatatt ggaccaagtt
    11221 attttcttaa gttgaaggat gtagattttg actatgaatt actctggtct gattatatta
    11281 agcctctcct agaagactac ttgcgaggtt cttatgatga ggttgaaact ttggaaactt
    11341 tgaaaaaagc atttgaactg acaaataatg agcaaaaaga tcaggcagta gctgatgaca
    11401 atgaaggtga tgaaaacgat gatgcggatt actgataatc aacacaagat tattaaagaa
    11461 aaatttgttg aagaatatcc taaactaagc aatcttattt tagacagaac cttggaaagt
    11521 ctatcccaag atgaacgtat tttcattttt ccaaatgatt tgactcatac tcctgatttg
    11581 gataaggacc aaaagatttt tgaaacagtc aatcagaaaa tcaagacagg gaacgtgatt
    11641 ggttttcttg gatatggtca ggaaagatta acgatttcct cacgattttc tgatgagagt
    11701 aatgaccatt ttttgcatta tctcttaaac aaggttcttc atatcaatct cactagttta
    11761 gatgttgctt tgtctcgtga agagaggctt tatcaacttt tggtgtatct ctttcccaag
    11821 tatctacaag ctgctattcg aaaaggtctt tataaggaat atcatcgatt ttctcataac
    11881 gacagtcatg ttaagggagt gattgatgta agaaaccatc tcaagaaaaa tcttcctttc
    11941 acgggaaata ttgcctacgc aacgagagag ttcacctatg ataatcccct catgcagttg
    12001 gtccgtcaca ctattgaata cattaagaat cagaaaagca ttggtcaagg ggtactagat
    12061 aatctctcaa ctagtcgtga aaacgtatct gaaatcgtgc gtgtaacgcc ctcttataaa
    12121 ctagctgatc gtgctaagat tattcgggga aatcaatcta aacctatacg tcatgcatac
    12181 tttcacgagt acagaaactt acaagaactt tgtctgatga tcctaaacca agaaaagcac
    12241 ggtttagggt atcaagatca aaaaatctat ggtattctct ttgatgttgc ctggctttgg
    12301 gaagagtatg tttatacctt gttgccaaaa ggttttgtac atcccagaaa taaggataag
    12361 acggatggaa tttcagtatt ttctgttggg aaacgaaaag tatatccaga tttttatgac
    12421 agagaacgaa agattgttct agatgcaaaa tataaaaaac tggaattgac tgaaaaagga
    12481 atcaaccgtg aggacttatt ccagctgatt tcctattctt atattttaaa agctgagaag
    12541 gctggacttg tttttccgag caaggacaag gttattgata atgagatggg aaacctagca
    12601 ggttatggag ctttgttgaa gaaatggtct atccaaattc ctcagaagtc ttcatcttat
    12661 agtgcatttt gtaaaatgat ggaaaattca gaagaaaatt ttaaagcgat tattgatgaa
    12721 gaagtgggga gaaaataatt tcctctcttt cttttatttt taacacaagt aaaacccgaa
    12781 caatatattt cgattcataa aataatttga caaaaactgt actttggttt ataataaatt
    12841 aaggaaacgt cggaaaaggc gtagtgatgc aagagcatag gtaggtcatt acaaaagaaa
    12901 cgagacatcg atatgttaaa tgaatttcca atttttgatt acgaagatat tcaattgatt
    12961 ccaaataaat gtgtcattaa aagccgtgca gaagcggata caagtgtcac tttaggaaat
    13021 cacaccttta aactacctgt tgtgccagcg aatatgcaga cgattttgga tgaaaatgta
    13081 gcagagcaac tggctaaagg tggttacttc tacattatgc accgttttga tgaggcagga
    13141 cgcattcctt ttattaaacg aatgcacgat caagggctca ttgcttctat ctctgtcggt
    13201 gttaaggact atgagtatga tttcgttaga cagctcaaga ctgatgctcc tgagtatatc
    13261 actattgata ttgctcatgg tcatgcggat agcgtgattt ctatgattca acacatcaag
    13321 aaagaattgc cagatacctt tgtcattgct ggaaatgtgg gaacaccaga agctgtgcgt
    13381 gaattggaaa atgctggtgc ggatgctact aaggtcggaa tcggtcctgg taaggtttgt
    13441 atcaccaagg ttaagactgg ttttggtaca ggtggttggc agttggctgc tctacgctgg
    13501 tgtgccaagg ctgcgcgtaa accgattatc gctgatggag gaattcgtac tcacggtgat
    13561 attgccaagt ctatccgctt cggtgctagc atgatcatga ttggttccct ctttgcagga
    13621 cacattgaaa gtccagggaa aacgattgaa gtcgatggtg aacagttcaa agaatattat
    13681 ggttcagcct cacaatatca aaaaggtgct tacaaaaatg tggaaggcaa acgtatcttg
    13741 cttcctgcta aaggtcatct gcaagacact ttaactgaga tggaacaaga ccttcaaagt
    13801 gctatttctt atgcaggtgg acgtcaggtt gctgacctta aacacgttga ttatgtgatc
    13861 gtgaaaaact ccatctggaa tggggatgct tcccactaag acggggtctt tgaccaaaaa
    13921 acttgttatt agagcaaatt tctgttataa taaaacaagt ttccaccctt agtgtaatgg
    13981 atatcacgta agattccggt tcttgagatg ggggttcgat tccctcaggg tggatgtaaa
    14041 catcctaaaa agcctttaat agggcttttt tctttatcct gacccaaatt tgccgctaaa
    14101 actgagaatc tctgtctaaa gaattcccaa atgctttcca gtcccgtttt agagtgactc
    14161 agggggcttt ttttgatata ataaaaagga ctattatcag ttagaaagag gttggtatga
    14221 aagaattaca aactgtacta aagaaccatt ttgcaatcga atttacagac aaaaagttac
    14281 tggaaactgc ctttactcat acgagttatg ccaatgagca ccgcctctta aaaatttcac
    14341 acaatgaacg cttggaattt ttaggagacg ctgttctaca gttattgatt tcagaatatc
    14401 tgtataaaaa atatcctaaa aagcctgaag gtgacctatc aaaactccgt gctatgattg
    14461 tccgtgagga gagtttagct ggttttgcgc gtgattgcca gtttgaccag tttatcaagt
    14521 tgggtaaagg ggaagaaaaa tctggtggtc gcaatcgtga caccattctt ggtgatgcct
    14581 ttgaagcctt tcttggtgcc cttcttttgg ataaggatgt ggccaaggtc aaggaattta
    14641 tctatcaagt catgattcct aaggttgaag caggcgagtt tgagatgatt acagactata
    14701 aaacccatct ccaagagttg cttcaggtca atggtgatgt ggctattcgt tatcaggtga
    14761 tttctgaaac agggcctgct cacgataagg tctttgatgt agaagttctt gttgaaggta
    14821 agagcatcgg tcaaggccaa ggtcgttcta agaaattagc agagcaggaa gctgccaaaa
    14881 atgccgttga gaaggggctg gattcatgta tttaaaggaa atcgaaattc aggggttcaa
    14941 gtcttttgct gataagacca aggtcgtttt tgaccaaggt gtgacggcag ttgttggacc
    15001 caatggatct ggaaagtcca atattacaga aagtctgcgt tgggctttgg gggagtctag
    15061 tgtcaagagt ctccgtgggg gcaagatgcc ggatgtcatc tttgctggaa cagaaagtcg
    15121 caaaccgctc aattatgctt ctgtagttgt gactctggat aatcatgacg gatttatcaa
    15181 ggatgcaggt caagaaatca gggtggaacg ccatatctat cgtagtggag atagcgaata
    15241 caagattgac ggcaagaaag tccgtctgcg tgatattcat gacctcttct tggatactgg
    15301 attgggacga gattccttct ctattatttc ccaagggaag gttgaggaga tttttaattc
    15361 taagcctgag gaacgacgag ctatttttga agaagctgct ggagttttaa aatacaagac
    15421 tcgcagaaaa gaaaccgaga gtaaactgca acaaactcag gataatctag accgcttaga
    15481 ggacattatc tacgagttgg ataatcaaat caagcctctt gagaagcaag ctgagaatgc
    15541 ccgtaagttt ttagacttgg aaggacaacg taaggctatt tatttagacg ttctggttgc
    15601 tcaaatcaag gaaaataagg cagaactaga gtcgacagaa gaagagctgg ctcaggttca
    15661 agaactcttg atgagttatt accaaaagcg tgaaaaatta gaagaagaaa atcaaactct
    15721 taaaaagcaa cgccaagatt tacaggctga aatggccaaa gaccaaggca gtttgatgga
    15781 cttgactagt ctgattagtg atttagaaag aaaattagcc ctatcgaaac tggagtccga
    15841 gcaagtggcc ttgaatcaac aggaggcaca agcccgtttg gctgctttgg aggataagag
    15901 aaattcactc agcaaagaaa agtctgataa agaaagctct ttagctctgt tagagggaaa
    15961 tctagtccaa aataatcaaa aactcaatcg tttagaagct gaattgctgg ctttctcaga
    16021 cgatcctgat cagatgattg agctcttacg tgaacgcttt gtagctcttt tacaagaaga
    16081 agcggatgtc tcaaaccagt tgacccgtat tgagaatgag ttggaaaata gtcgtcagct
    16141 ttctcaaaaa caagcagatc aactagaaaa gctgaaagag caattagcta tagctaaaga
    16201 gaaggctagt cagcaaaagg aagagcttga aactgccaag gagcaggttc agaaattatt
    16261 ggctgactac caagctattg ccaaggagca agaggagcag aaaacttcct atcaagctca
    16321 acaaagtcaa ctctttgacc gtctggatag tctcaaaaac aagcaggcca gagctcaaag
    16381 tttggaaaat atcctgagaa atcatagtaa cttttatgca ggtgttaaga gtgttctcca
    16441 agaaaaagat cgcctaggtg ggattattgg tgcagtcagt gagcatctga cctttgatgt
    16501 ttattatcaa actgccctag agattgcctt aggggcaagt agccagcata tcatcgtaga
    16561 agatgaagag tcggcaacca aggctattga cttccttaaa cggaacagag ccggtcgtgc
    16621 aacctttctt cctttgacca ctattaaggc gcgtacgatt tctagtcaga accaagatgc
    16681 tatcgctgta agcccaggtt tccttgggat ggcagatgag ttggtgactt ttgatactag
    16741 actggaagcc attttcaata atttgctagc tacaacggct atctttgata ccgtggagca
    16801 tgcgcgtgca gcagcgcgcc aggttcgtta tcaggttcgc atggtgacat tggacggaac
    16861 agagctgcgc acaggtggtt cttatgcagg tggagctaat cgccagaata acagtatttt
    16921 catcaagcca gaactggagc aattacaaaa agaaattgct gcagatgaag caagcttggg
    16981 ttcagaagaa gcggctttga agaccttgca agatgagatg gccagattga ccgagtcatt
    17041 agaagctatt aaatctcaag gagagcaggc acgtattcag gagcaaggct tgtccctcgc
    17101 ttatcagcaa actagtcagc aagttgaaga actggaaact ctttggaaac tccaagaaga
    17161 ggaaatagat cgtctttccg agggagattg gcaagcggat aaggaaaaat gccaagagcg
    17221 tcttgctgca atcgccagtg acaagcaaaa tctggaagct gagattgaag agattaagtc
    17281 taataaaaat gccatccaag aacgctatca aaacttgcag gaagagctag cgcaagctcg
    17341 tttgcttaag acagaactgc aagggcaaaa acgttatgaa gttgctgata ttgaacgctt
    17401 aggcaaggaa ttggacaatc ttgattttga acaagaggaa atccagcgcc ttcttcaaga
    17461 aaaggttgac aatcttgaga aggttgatac agaattgctc agtcaacagg cggaagaatc
    17521 caaaactcag aaaacgaacc tccaacaagg tttgattcgc aaacagtttg agttggatga
    17581 tatagaaggt cagctggatg atattgctag tcatttggat caggctcgcc agcagaatga
    17641 ggagtggatt cgcaagcaaa cacgtgctga agctaagaaa gaaaaggtca gcgagcgctt
    17701 gcgccatcta caaagtcaat taacagacca gtaccagatt agctatactg aagctctaga
    17761 aaaagcgcat gaattggaaa acctcaatct ggcagagcaa gaagttaagg atttagagaa
    17821 ggctattcgc tcactgggtc ctgtcaatat agaagctatt gaccggtacg aagaagttca
    17881 caaccgtctg gactttctaa atagtcagcg agatgatatt ttgtcagcga aaaatctgct
    17941 ccttgaaacc attacaaaga tgaatgatga ggttaaggaa cgctttaaat caacctttga
    18001 agctattcgt gagtccttta aagtgacctt caagcagatg tttggcggag gtcaggcaga
    18061 cttgatattg actgagggcg accttttaac agctggtgtg gagatttctg ttcaacctcc
    18121 aggtaagaaa atccagtcgc ttaacctcat gagtggtggt gaaaaagccc tatcggctct
    18181 tgccttgctt ttctccatta ttcgtgtcaa gaccattcct tttgtcatct tggatgaggt
    18241 ggaagctgcg ctggatgaag ccaatgttaa acgttttggg gattacctca accgctttga
    18301 caaggacagc cagtttatcg tcgtaaccca ccgtaaggga accatggcag cggccgattc
    18361 catctatgga gtgaccatgc aagaatcggg tgtttcaaag attgtttcag ttaagttaaa
    18421 agatttagaa agtattgaag gatgacaatt aaactagtag caacggatat ggacggaacc
    18481 ttcctagatg ggaatggacg ctttgatatg gatcgcctca agtctctttt ggcttcctac
    18541 aaggaaaaag ggatttactt tgcagtagct tcgggtcggg gatttctgtc tttagaaaaa
    18601 ttatttgctg atgtacgtga tgacattatt ttcatcgcgg aaaatggcag tttggtcgaa
    18661 tatcaaggtc aggacttgta tgaagcgacc atgtctcgtg agttttatct agcaactttt
    18721 gaaaagctga aaaagtcacc ttatgtagat atcaataaac tgctcttgac gggtaagaag
    18781 ggttcatatg ttctagatac ggttgatgag acctatttga aagtgagtca gcattataat
    18841 gaaaatatcc aaaaagtagc gagtttggaa gatatcacag atgacatttt caaatttaca
    18901 accaacttca cagaagaaac gctagaagct ggagaagctt gggtcaatga aaatgttcct
    18961 ggtgtcaagg ctatgacaac tggctttgaa tctattgata ttgttctgga ctatgtcgat
    19021 aagggtgtag ctattgttga attagctaaa aaacttggta tcacaatgga tcaggtcatg
    19081 gcttttggag acaatcttaa tgacttacat atgatgcagg ttgtgggaca tcctgtagct
    19141 cctgaaaatg cacgacctga aattttagaa ttagcaaaga ctgtgattgg tcaccataag
    19201 gaacggtcgg ttatagctta tatggagggc ttataatggc agatataaaa ttgattgcat
    19261 tggacttgga cgggaccttg ctgactactg ataaaaggct gacggatcgt accaaggaaa
    19321 ccttgaaagc tgcgcgtgat cgtggtatca aggtcgtatt gacaactggt cgtcccttaa
    19381 aagccatgga tttctttctc catgagttag ggactgacgg tcaggaagat gagtatacca
    19441 ttacttttaa tggtggatta gttcagaaaa atacaggaga aatccttgat aaaacagtct
    19501 tttcatatga tgatgtggca cgtttgtatg aagaaacaga gaaattatca ctgcctcttg
    19561 atgccatctc agaaggaaca gtttatcaaa tccaatcgga ccaagaaagt ctttatgcca
    19621 aattcaatcc agctttgacc tttgttccag tggactttga agacttatct agtcaaatga
    19681 cctacaacaa atgcgtgact gcctttgctc aagaaccctt ggatgcagcc attcagaaga
    19741 tttctccaga attgtttgac caatatgaaa tctttaaatc acgtgaaatg ttgctagagt
    19801 ggtcaccaaa gaatgttcat aaagcaacag gtttggcaaa actaatcagc catcttggaa
    19861 tcgaccaaag ccaagtcatg gcttgtggtg acgaggccaa tgacctctct atgattgaat
    19921 gggcagggct tggtgttgcc atgcaaaacg ctgttcctga agtcaaggca gtcgcaaatg
    19981 tggtgacgcc aatgaccaac gatgaagagg ctgtcgcctg ggctatcgaa gaatatgtgc
    20041 taaaggagaa ctaagatatg ggattatttg accgtctatt cggaaaaaaa gaagaaccta
    20101 aaatcgaaga agttgtaaaa gaagctctgg aaaatcttga tttgtctgaa gatacggagc
    20161 ctgcccttac agaagctgag gaagcttctc aagaagaagc agaggttgaa attgttgaac
    20221 aagctgtgct ccaagaagtg gaaaatcaag acacagttga agagagtcag gattcagagc
    20281 caactgtagt agtttctcaa gaagaagtcg aagaattgcc aaactcagaa gaagtcttag
    20341 aggaagagaa tcctgagcac gaacgaactg tagaagaaaa taattctgaa gttcttgaag
    20401 cagaaagacc tcaagtagaa gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa
    20461 ctcgtacagg cttcggtgct cgcttgaatg ccttctttgc taacttccgc tctgttgacg
    20521 aagaattttt cgaggaactg gaagaactgc tgattatgag tgacgttggt gtccaggtgg
    20581 cttctaactt aacagaggag cttcgttacg aagccaagct tgaaaatgcc aagaaacctg
    20641 atgcacttcg ccgtgtcatc attgagaaat tggttgagct ttatgaaaag gatggcaact
    20701 acgatgaaag catccacttc caagatggct tgacagtcat gctctttgtt ggtgttaatg
    20761 gtgttgggaa aacaacttct attgggaaac tagcccaccg ctacaaacaa gcaggtaaga
    20821 aggtcatgct ggttgcggca gataccttcc gtgcaggggc agtagcccag cttgctgaat
    20881 ggggccgtcg tgtggacgtt ccagtggtga ctggacctga aaaagctgac ccagctagtg
    20941 tcgtatttga tggcatggaa cgtgccgtgt ccgaaggtat cgatattctc atgattgata
    21001 ccgctggtcg tctgcaaaat aaggataacc ttatggctga gttggaaaag attggtcgta
    21061 tcatcaaacg tgttgtgcca gaagcacccc atgaaacctt cctagcatta gatgcttcaa
    21121 caggtcaaaa cgctcttgta caggccaaag aattttcaaa aatcactcct ttaactggaa
    21181 ttgtcttgac taagattgat ggaactgctc gaggaggtgt tgttctagcc atccgagagg
    21241 aactcaatat tcctgtaaaa ttgattggtt ttggtgaaaa aatcgatgat attggagaat
    21301 ttaactcaga aaactttatg aaaggtctct tggaaggctt aatctaatca gaagcaaaaa
    21361 tcctgcaagc tacaaacttg caggaaattt ttttattcta aacgaccatc ttgacgatag
    21421 gcgatatctg gttgccaagt ccatttggca ccgaattttt caagtaagtc aaagcttgct
    21481 tgaggtccca tgcttccagc tttatagtca tgaagtgggg caccattttc agcccagagc
    21541 tcttcgatac ggtcaatcaa tttccatgac gcaccaactt catcccagtg gctaaagtta
    21601 gttgagttgt tatttaggac atcataaatc aatttttcgt atggttctgg agaagcacca
    21661 gttgcagtcg catctgtacg gtaatcaagt gagttaggag ccaagttaaa ttcttctcct
    21721 acttgcttcc catttaggct aagagagaag ccttctgttg gttgaatata gatggtcaaa
    21781 atatttggag caagtggttc tccaaagata gaatccattt gtttaaagac gatgttgaca
    21841 tgagttcctt tttcagtcag tcgtttacct gtacggaaaa agaaaggaac accacggaat
    21901 cgatcgctgt ctacaaagaa ggcaccagat gtaaaggttt cagttgttga ttctggattc
    21961 acatttggtt cgctacgata agagatgtat ttcatgccat caatcttacc agagcggtat
    22021 tgcccacgga taaagtgttc tttgagttct tcatcagttg gatgatagag gtttttaaag
    22081 accttaatct tttcagcacg aatctcgtct tttgtgaagc ttgctggttt gtccatggcg
    22141 aggagcgaaa gaagttgtag agtgtggttt tggaccatgt cacggagggc acccgattgg
    22201 tcatagtagc caccacgttc ttctacaccc aagcgctccg caaaggtaat ttgaacattg
    22261 tcgataaaat ccttgttcca aacgttttca aaaatcaagt ttgcaaagcg aactgcaaag
    22321 atgctttgga tcatttcctt accaagataa tggtcgatac ggaaaatttg ttcttcgtca
    22381 aatgttgcta ggagttcgtc attcaacttg cttgcagttg cgtaatctgt accaaatggt
    22441 ttttcaacga tcaagcgctc aaaacctttg ccatcgacaa tgttttcaga tttgaggtgt
    22501 ttggcaatgg ttccaaagaa ctgaggtgcc atagacaaga agaagagctt attgtgttca
    22561 gcttggtatt tttcattaag ctcagcttgt aattgacgca aagcaatata atgttccgaa
    22621 tcattgacat catggctttg atagtagaag tggctagcaa attcttgggc ttgctcggta
    22681 ctatctgcca aatcaaggat ggactcgaca actacagatt caaaatattc cttactccaa
    22741 ggtctacggg cagttccaat aacggcaaag tgcttggaaa gattgccgga tttatatagt
    22801 ctaaaaaggg aagggtagag cttgcgttta gccaggtctc cactcgcacc gaaaattgta
    22861 acaataacct tagatgacat ctagctacct aatttctatt tttattccta gtcttgctag
    22921 gtatgaggaa gcctcatttc ataaacttaa ttctaacata attttccgaa aaatcaaaaa
    22981 ttccaatacg aggtagaaaa actgcaagga aatccttaca gtttgagttt agacgtttaa
    23041 gaccttatct aagaactctt tcagacgagg gtgttgtggg ttatcaaaga tttggtcagg
    23101 tgttccgtct tcaaggaact cgccatctgc agtaaagata acgcggttgg caacctgacg
    23161 agcaaatccc atctcatggg ttacgataat catggtcatg ccttgctcag ccaattcctt
    23221 cataacgtta agtacgtctc caaccatctc agggtcaagg gcagaagttg gttcatcgaa
    23281 gagcatgatg tctggattca ttgctaggcc acgagcgatg gccacacgtt gtttttgacc
    23341 acctgatagg ctatctggat tggcattagc tttatctgct agtccaacct tttcaagcaa
    23401 ctccattccc aattcctcag cttcttcctt agtcatcaac ttgtgctcaa taggagcaaa
    23461 ggtgatgttg tccaatacag acatatgagg gaataggttg aagtgttgga ataccatgcc
    23521 gatattttca cggacgtggt caacattggt tgttttttca gttaaatcat agccgttcac
    23581 agtgatgtga ccgctagtga cttcttctaa aagattgagg ctacggagga aagttgactt
    23641 accagaacct gaaggaccga tgatacaaac aacatctcct tcatagaact tagtcgtaat
    23701 tccttttagg acttcatttt ttccatagtg cttgtgtaaa tcatttacat caatttttaa
    23761 ttttgccatt aacgaatcct cttttctaag cgtttcgcta gtctagtcaa aagtgtgata
    23821 attacaagat agaagatagc aaggattgca tacatcttga aactttggta gttacgagca
    23881 atgataatct taccagtttg gaagagttca accaaaccga tagcagatac gatagttgta
    23941 tctttaagag cgataacaaa ttggttgaca aagtttggca acatcaattt agttgcttgt
    24001 ggcaagataa tcttacgcat ggtttttcca taagagatac ccaagcttcg gctggcttcc
    24061 atttggccaa ctggaacggc ctgaatacca ccacgaacga tttcagcgat ataagcagcc
    24121 gcattgagtg agagggcaat ggttccagct acaaagtcgt taattgggct ttgttggcct
    24181 gtgatagact cgatgaagtt tggaattccc cagaagatga aggctgcaag aatcatcaat
    24241 ggaataccac gaataacgtc aacgaaaatc tcagagatga cgcgaagaga tttgtatggg
    24301 ctaacgctaa acataccgaa gataattccg atgacaatgg caatagcaaa tgagataaga
    24361 gctagagcaa gagtgatacc aagaccgcta aggagttgtt tgtagttgtt ttgaagcaag
    24421 ccccagagcg ttgtttcgtc aacagtactt gttgaagcag ttgaagattc gctagctagg
    24481 tatttgtcaa gaatcttttg gaattcaccg tttgctttaa ggtttgcaag tccgttgttg
    24541 aacatttcaa tcagttctgg atttgctcct tttttaacgg caaaggctgt ttcaccgatt
    24601 ggagttccag agattggagt tttcaatttt tgaccttggc tgatagaata tttgagaaca
    24661 ggttcatcat ccataacggc atcaatggca ccagtgttta aactgtcata cattgaagaa
    24721 ccatcagcaa aggttttgat tttgtaaccg tattttcttt gattttctgt taggaaggtt
    24781 tgagaagcag ttccgttttt aacaccgact gtctttcctt ttagatcttc ataagaagca
    24841 atattgcttg attctttgac accaagaatg gtattagcag tgtagtatga ttctgagaag
    24901 tcaaaagttg ccttacgagc atctgtgaca gacataccag caatgatacc atcggcttga
    24961 ccagcttgga cagcactgat agcagcatca aaaccagggt tggtgatttc aatttcaaaa
    25021 ccttggtctt tagcgattgc cttaatcaat tccatatcaa taccagtgta ttggttgctt
    25081 gaattttgga aaacaaaagg tgcaaaagaa gaatcgctgg caatgatata tttagcctta
    25141 acaggaatag cttttaatcc tgcgagagta gttgtagttg gcactgctga agatgatgaa
    25201 gcagtccatt tcttgataat tttatcaaga ctaccatctt ttttcatttc agccaaggct
    25261 tggttaaatt cagtaaccag gtgctcgtat ttacttcctt ttttcacacc gaaagcaaaa
    25321 cttcctacag cttcaccatc catttcaata tggaggtctt gaccttggtt aatggcatat
    25381 tcgataacag gtttgtcatc catcatggca tcgatggcac cagcactcaa gctgttgttc
    25441 attaaatcac cagtgtcaaa tgttttaata gtaaagccgt atttatcttt gattgtttca
    25501 aggaaacgtt gagcggcagt tccgttttta acaccaacgg ttttgccagt taattggtcg
    25561 tacttgctaa ttttgtgtga ctttgtagta gcaatgacaa cttttgtatc atagtaagta
    25621 tcagacatgg tgaagacttt ttcacgttct ttagtctttg tcatccctgc catgatagcg
    25681 tcggcttgcc cagcttgaac cgcattgact gctgcgtcaa atccaggata ggacatctga
    25741 atgttccagc ctttaatctc agcgactttg ttaataatgt caacatcaat tcctttataa
    25801 gtttgatctg aatctttaaa ctcaaaaggt gcataggcgg tatcagaaac aatcttaatc
    25861 gtttctgctt tggcaatacc taatgagaaa attgggaata aaattagcaa aaatgctaga
    25921 aattttttct tcatttttag tctccttttc cgaatattct ctcattatat cagaaaaagt
    25981 aaaaaaaggc aaatttttat atttttcgtg tcagaaaata taacattgat ttttcctttt
    26041 ctttcttgaa ttgctattaa aaagtgctat gataatagta tatatagaag aaaagaggac
    26101 ggggatatga agaacaaaag aatatttaaa gacttccaag cttcaaaaat gaatttaaac
    26161 atttacacaa gccctttgtt agcctttgtt tttgtcttca taggagagtt tgtggcttat
    26221 actttatatg gtattagttt gttagctctc atcggacttg ctagaaattt tggagaggct
    26281 ggtcaaaatc ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga taaaacaagt
    26341 gactttcgtt taattttagg attactggcc tttggtttta ttcttaacac tgtgttcaga
    26401 tggacaagaa aagttgagaa aagacctatt cgaaccttgg gattttatag agagaatttc
    26461 ctcagcaatc ttctgaaagg atttagtcta ggcctggcac tttttcttct gaccttgtta
    26521 ggtttagtgg tcttaggtca atatcgtttg gaatccattc acttgaatcc ttattctctt
    26581 gcctttgtcg tctttactat cccattttgg attttacagg ggacagcaga agaagtggtg
    26641 gcccgtgctt ggctacttcc tcaattggcc tcaagaacca atctaaaact agctattctt
    26701 atatctagcc tgttctttac cctgcttcat atgggcaatt ctggcctcac ccctctatct
    26761 ctagtaaatc tctttttatt cggagttacc atggctcttt accttctcaa aactgataca
    26821 gtttggggtg ttgcaggtat tcatggtgct tggaattttg ctcagggtaa tctctttggg
    26881 attttagtta gtggtcaacc gtcaggaacg tctctgatga cctttttacc acaaggcaat
    26941 caagattggc tatcaggtgg ttcttttggc atagaaggtt ccattatgac aagtctggta
    27001 ttactactgc tgattgtcta tcttgctaat aaattaaaga aagaaaatga aaggatgtga
    27061 cttcggtccg tccttttctt cgtgaaaata ctataagtat gctaaaatag ggatagcaca
    27121 tggagagagg attcttatga tcaatcacat tacagataat caatttaaac tagtatcaaa
    27181 atatcaacca tcaggagatc aaccccaagc tatcgagcag ttggtggata acattgaggg
    27241 gggagaaaaa gctcagattc tgatgggggc gactggaaca gggaagacct atactatgag
    27301 tcaggtcatt tctaaagtca ataaaccaac tctggttatt gcccacaata aaactctggc
    27361 cggtcagctc tatggggagt ttaaggaatt tttccctgaa aatgcagttg agtatttcgt
    27421 atcctactat gattattacc agccagaggc ctatgtccct tctagcgata cctatattga
    27481 gaaggatagt tctgtcaatg acgagattga caagcttcgc cactcagcta cctcagccct
    27541 tttggagcgt aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg gtttgggttc
    27601 gcccaaggaa tacgctgata gtgtcgttag tctccgtcct ggtctagaga tttctcgtga
    27661 taaactcttg aatgacttgg tcgatattca gtttgaacgc aatgatattg atttccaacg
    27721 cggaagattt cgcgttcgtg gggatgtggt agagattttc ccagcttccc gagatgaaca
    27781 tgcctttcga gtagaatttt ttggagacga aattgaccgt attcgtgaag ttgaggctct
    27841 gacaggtcag gtgttgggag aagtggatca tttagcgatt ttcccagcga cacactttgt
    27901 gaccaatgac gaccacatgg aagttgccat tgcaaagatt caggccgagt tggaagaaca
    27961 attagctgtc tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga aacagcggac
    28021 agagtatgat atcgaaatgt tgcgtgagat gggctatacc aatggggttg aaaattattc
    28081 tcgccacatg gatggacgga gcgaaggaga gcctccttat acgcttctcg acttcttccc
    28141 agatgatttc ttgattatga ttgacgagag tcatatgacc atagggcaaa tcaagggcat
    28201 gtacaatgga gaccgttcgc gtaaagaaat gctggttaat tatggtttcc gtttgccgtc
    28261 tgctttggac aatcgtcctc tacgtcggga ggagtttgag agtcacgttc atcagattgt
    28321 ttacgtttca gcgacacctg gtgactatga aaatgaacag accgagacag tgattgagca
    28381 aatcattcgt ccaacgggac tcttggatcc agaggtggaa gtccgtccga ctatgggaca
    28441 gattgatgac ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc gtacctttat
    28501 cacaactttg accaagaaaa tggcagagga cttgaccgac tacttcaagg aaatgggtat
    28561 caaggtcaag tacatgcact cggatatcaa gaccttggaa cggacggaga ttatccgtga
    28621 cctgcgcttg ggtgtctttg atgtcttggt cggaattaac ctgctccgtg aaggaattga
    28681 cgttcctgaa gtgagcctcg tagctattct cgatgctgac aaggaaggtt tccttcgcaa
    28741 cgaacgtgga ctcatccaga ctattggacg tgctgctcgt aacagtgaag gccatgtcat
    28801 catgtatgca gacacggtta cccagtctat gcaacgtgct atcgatgaaa ctgcccgccg
    28861 tcggaaaatt cagatggcct ataatgaaga gcatggtatc gtaccacaga caatcaagaa
    28921 agaaatccgt gacctgattg ccgtgaccaa ggcagttgct aaggaagagg acaaggaagt
    28981 cgacatcaat agcctcaaca aacaagagcg caaagaactc gtcaagaaac tagaaaaaca
    29041 aatgcaagaa gccgtcgaag tgcttgactt tgaactggcg gctcagatcc gtgatatgat
    29101 gttggaagtc aaggccttgg attaggggaa tagtatgatt tatttaagaa agttaaagag
    29161 agaagatttg atgtctttat gggaaatggc ttattcacaa cttaatccag tttggaaaca
    29221 gtatgatgct ccctattatg atgattatca gtatttttca aattttaaag aattcgaact
    29281 acaaaaatca gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa
    29341 actagttggg actgtttcgc gttattgggt atgtaaacaa acaagatgga tggaattggg
    29401 aattggtatt tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca
    29461 gtggatagat aggacgtttc aggattactt ggagttggag catctgggtt tgacaacttg
    29521 gtcaggaaat cttggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca
    29581 tattccaaaa gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt
    29641 gagagaagac tgggagaaaa taaatgacgg ttattatcaa atcaatggaa actcctgaag
    29701 agatagaagg taaatccctc gttcactggc aaacgtggag agaggcttat gatgaccttt
    29761 tgcctgcaga atttcaggag acaatgacat tagaaagatg tcgattcttt agtcaaaagt
    29821 atccagaaaa tacattgatt gcgataggtg atctgaaggt agttggtttt atcagttatg
    29881 gtaactttcg tgatgagact attcaagctg gtgaaattat tgctttatat gttttaaaag
    29941 actattacgg aaaaggcata gcacaaaagt taatgaaaac agctttgact gctctgaatc
    30001 atttttctga aattttctta tgggtattga aagataacaa gcgagccatt gctttctatc
    30061 aaaaaatggg ttttactttt gatggacaag aaaagatact tgaacttgga aagcctataa
    30121 aggaaaaacg aatggtattc tattctaaaa taattttaaa aagtagaagc taatggcact
    30181 ggtaccaagt ctgaaaattt aataaattag aaagcgagta aatttatgtc ccgttcccaa
    30241 ttaacgattt taacaaccat ttgtctgatt gaagacctcg aaacgcagcg cgtggtgatg
    30301 cagtatcgct ctcctgcaac caatcgctag tctggttatg cctttccagg aggtcatgta
    30361 gaaaatggcg agtctttcgc agagtctgtc attcgtgaaa tctatgaaga aacagggttg
    30421 actatccaaa atcctcaact tgtcggcatt aaaaattggc cactagatac aggtgggcgc
    30481 tatattgtca tttgttataa ggcgactgag ttctctggta cccttcaatc ttcagaagag
    30541 ggagaagttt cttgggtgca aaaagaccag attccaaact tggatctggc ctatgatatg
    30601 ttacctttga tggagatgat ggaagctcct gacaaatctg aatttttcta cgctcgccgt
    30661 acagaagatg attgggagaa gaaaatcttc tagtctttta ctaaataacc tagctgatcc
    30721 aaggcctcct cgatatagtg gaggtcttgt tgtgtttcgg cttcgactag gtggtaatgg
    30781 atgccctctg tcaattcaga cagaggtcta aagtcagaat gttcgacttg ttctagaaaa
    30841 tgttgcacgt ctcggcgaca ggacagtttc agcaaggttt caatttctcc ataaacggga
    30901 tggtcaatca aggtattctg gacacgacct ccattatcta cgatagcaag gagttcctga
    30961 ccgatttctt caacttcatg tttcactttg aacagtttgt gaacataagg attggtatca
    31021 acttgcttat agacgtagcc acgattagtg gataggatag gagcaccatc ggctctcaaa
    31081 attgcaatgt cttgtacaat gacctgacgt gtgacatgaa aatgttcagc caaactttgg
    31141 ccattgaggg ctttaggagc ttctttcaag agttggagca gggcttgttt gcgatctttt
    31201 gtcatagttc ttccttttaa cggcgttttc gaagcacttt atagacagct agtgctaatg
    31261 tatagtctac catactatgg ataattgtgc caaatccaac tagcacaaag agaacataaa
    31321 acatattttc tacattggta ccggaagttg cgtaaaaaag aacacaggcc aatacttcag
    31381 caagggcatg aacaacagct aaaacaaagt tgaaaatcaa ggaagatttt ggtttatcta
    31441 gggtatcggg gaatttttgt aggtaaagag ctcccaaagt cccaaaaaag atatgggaaa
    31501 aagctcgaaa tacgataacc ataggatagc cagccatcaa aaatccaaaa ctagaggcta
    31561 ggatgacaaa aactgccatc aagggcgaca agaacatggc aataaaaata gcgatatggc
    31621 tccccaaagt gtaagaagca ggtggaatga cgatcttgaa aggcataacg attggaatca
    31681 aaatcgcaat agccgttaag agggctgtca ttgtcataaa ttgtgtcttt ttccgtgtat
    31741 tcatcagaat ctccttttta actgtatata cattagtata gtacaataaa ccagacaata
    31801 aagcaagaat ttacttgggt ttatagatca ttttttagtt aaaagttata gt
//
LOCUS       DAVLHB010000022        30396 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLHB010000022 DAVLHB010000000
VERSION     DAVLHB010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.022"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            720..1712
                     /locus_tag="VXE36_001124"
     CDS             720..1712
                     /locus_tag="VXE36_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0779439.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VXE36_001125"
     CDS             1714..2532
                     /locus_tag="VXE36_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0779440.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VXE36_001126"
     CDS             2534..3319
                     /locus_tag="VXE36_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779441.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VXE36_001127"
     CDS             3417..3635
                     /locus_tag="VXE36_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0779442.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3781
                     /locus_tag="VXE36_001128"
     CDS             3620..3781
                     /locus_tag="VXE36_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0779443.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
     gene            complement(4243..4317)
                     /locus_tag="VXE36_001129"
                     /pseudo
     CDS             complement(4243..4317)
                     /locus_tag="VXE36_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4550..10984
                     /locus_tag="VXE36_001130"
     CDS             4550..10984
                     /locus_tag="VXE36_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0779444.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            11616..12091
                     /locus_tag="VXE36_001131"
                     /pseudo
     CDS             11616..12091
                     /locus_tag="VXE36_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            12129..12431
                     /locus_tag="VXE36_001132"
     CDS             12129..12431
                     /locus_tag="VXE36_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0779445.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            12439..13243
                     /locus_tag="VXE36_001133"
     CDS             join(12439..12807,12809..13243)
                     /locus_tag="VXE36_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0779446.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQIPRKSSKLKPLIAEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            13292..13756
                     /locus_tag="VXE36_001134"
     CDS             13292..13756
                     /locus_tag="VXE36_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0779447.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            13914..14339
                     /gene="lacA"
                     /locus_tag="VXE36_001135"
     CDS             13914..14339
                     /gene="lacA"
                     /locus_tag="VXE36_001135"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0779448.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            14370..14885
                     /gene="lacB"
                     /locus_tag="VXE36_001136"
     CDS             14370..14885
                     /gene="lacB"
                     /locus_tag="VXE36_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0779449.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            14896..15825
                     /locus_tag="VXE36_001137"
     CDS             14896..15825
                     /locus_tag="VXE36_001137"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0779450.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            15827..16807
                     /gene="lacD"
                     /locus_tag="VXE36_001138"
     CDS             15827..16807
                     /gene="lacD"
                     /locus_tag="VXE36_001138"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0779451.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            17041..17877
                     /locus_tag="VXE36_001139"
     CDS             17041..17877
                     /locus_tag="VXE36_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0779452.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            17913..18230
                     /locus_tag="VXE36_001140"
     CDS             17913..18230
                     /locus_tag="VXE36_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0779453.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            18232..19926
                     /locus_tag="VXE36_001141"
     CDS             18232..19926
                     /locus_tag="VXE36_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0779454.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            20141..21547
                     /gene="lacG"
                     /locus_tag="VXE36_001142"
     CDS             20141..21547
                     /gene="lacG"
                     /locus_tag="VXE36_001142"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0779455.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVNNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            21590..21847
                     /locus_tag="VXE36_001143"
     CDS             21590..21847
                     /locus_tag="VXE36_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0779456.1"
                     /translation="MFKDFIQSIYEKVYIINFEKYSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEEWDTISFDSDFMLFQQS"
     gene            complement(22126..22887)
                     /locus_tag="VXE36_001144"
     CDS             complement(22126..22887)
                     /locus_tag="VXE36_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0779457.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(23069..24031)
                     /gene="nrdF"
                     /locus_tag="VXE36_001145"
     CDS             complement(23069..24031)
                     /gene="nrdF"
                     /locus_tag="VXE36_001145"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0779458.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(24219..26378)
                     /gene="nrdE"
                     /locus_tag="VXE36_001146"
     CDS             complement(24219..26378)
                     /gene="nrdE"
                     /locus_tag="VXE36_001146"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0779459.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(26460..26678)
                     /gene="nrdH"
                     /locus_tag="VXE36_001147"
     CDS             complement(26460..26678)
                     /gene="nrdH"
                     /locus_tag="VXE36_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0779460.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            27029..27292
                     /locus_tag="VXE36_001148"
     CDS             27029..27292
                     /locus_tag="VXE36_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0779461.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            27298..29031
                     /gene="ptsP"
                     /locus_tag="VXE36_001149"
     CDS             27298..29031
                     /gene="ptsP"
                     /locus_tag="VXE36_001149"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0779462.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFEAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEDKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            29285..>30396
                     /locus_tag="VXE36_001150"
     CDS             29285..>30396
                     /locus_tag="VXE36_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0779463.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QAAQKTENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEEPSP"
BASE COUNT        10030 a         5078 c         6188 g         9100 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta caaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tatttcatga
      541 gagaaatcct aatttcacaa tctataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttctgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aacattttgt gaagattgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg agcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca aaagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttcg tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttaatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgtt gaggttttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaaggttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagg ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt tctcagctat ggaatccgta
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag
     3841 agtgccatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttattctt agcggttatt tatattgttt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcatagaa
     4141 aatctcttca aaccacgtca acgtcgcctt gccgtgcgta tggttactga cttcgtcagt
     4201 tctatccaca acctcaaaac agtgttttga gctgactacg tcagttccat ctacaacctc
     4261 aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga
     4321 gtactaatct tattttttaa cgtgtgctaa aaaataaatt aatgcatgtt aatttttctt
     4381 gaattaaatt tttttaaatg atatactgtt tttatggaga gataacaatt atatataaat
     4441 gtactactct atttcctaga taatacttag taaaactttt tataacaaag gctagcaaag
     4501 ttaaagttta ttatctattg gaagttaaat aaatatgtaa ggaattaaaa tgaaaaaaag
     4561 tacagtattg tcattaacca cagctgcagt tattttagca gcctatgccc ctaatgaggt
     4621 agtcttagca gacacatcta gctctgaaga tgctttaaac atctctgata aagaaaaagt
     4681 agtattagat aaggaaacag aaaataaaga gaaacatgaa gatattcata atgctataga
     4741 aacttcaaag gatactgaag aaaagaaaac aacagttatt gaggaaaaag aagttgttag
     4801 taaaaatcct gtgatagaca ctaaaactag caatgaagaa gcaagaatca aagaagattc
     4861 caatcaatcc caaggagata atgcacactc gtctgcaaat aaaggcacag aaaatccgaa
     4921 aaaagaagat agacttgtct atattgctga atttaaagat aaagaatctg gagaaaaagc
     4981 aatcaagcaa ctatccaatc ttaagaatac aaaagtttta tatacttatg atagaatttt
     5041 taacggtagt gccatagaaa caactccaga taacttggac aaaattaaac aaatagaagg
     5101 tattacatcg gttgaaaggg cacaaaaagt ccaacccatg atgaatcatg ccagaaagga
     5161 aattggagtt gaggaagcta ttgattacct aaagtctatc aatgctccgt ttgggaaaaa
     5221 ttttgatggt agaggtatgg tcatttcaaa tatcgatact ggaacagatt atagacataa
     5281 ggctatgaga atcgatgatg atgccaaagc ctcaatgaga tttaaaaaag aagacttaaa
     5341 aggaactgat aaaaattatt ggttgagtga taaaatccct catgcgttca attattataa
     5401 tggtggcaaa atcactgtag aaaaatatga tgatggaagg gattattttg acccacatgg
     5461 gatgcatatt gcagggattc ttgctggaaa tgatactgaa caagatatca aaaactttaa
     5521 cggcatagat ggaattgcac ctaatgcaca aattttctct tacaaaatgt attctgacgc
     5581 aggatctggg tttgcgggtg atgaaacaat gtttcatgct attgaagatt ctatcaaaca
     5641 caacgttgat gttgtttcgg tatcatctgg ttttacagga acaggtcttg taggtgagaa
     5701 atattggcaa gctattcggg cattaagaaa agcaggcatt ccaatggttg tcgctacggg
     5761 taactatgcg acttctgctt caagttcttc atgggattta gtagcaaata atcatctgaa
     5821 aatgaccgac actggaaatg taacacgaac tgcagcacat gaagatgcga tagcggtcgc
     5881 ttctgctaaa aatcaaacag ttgagtttga taaagttaac ataggtggag aaagttttaa
     5941 atacagaaat ataggggcct ttttcgataa gaataaaatc acaacaaatg aagatggaac
     6001 aaaagctcct agtaaattaa aatttgtata tataggcaag gggcaagacc aagatttgat
     6061 aggtttggat cttaggggca aaattgcagt aatggataga atttatacaa aggatttaaa
     6121 aaatgctttt aaaaaagcta tggataaggg tgcacgcgcc attatggttg taaatactgt
     6181 aaattactac aatagagata attggacaga gcttccagct atgggatatg aagcggatga
     6241 aggtactaaa agtcaagtgt tttcaatttc aggagatgat ggtgtaaagc tatggaacat
     6301 gattaatcct aataaaaaaa ctgaagtcaa aagaaataat aaagaagatt ttaaagataa
     6361 attggagcaa tactatccaa ttgatatgga aagttttaat tccaacaaac cgaatgtagg
     6421 tgacgaaaaa gagattgact ttaagtttgc acctgacaca gacaaagaac tctataaaga
     6481 agatatcatc gttccagcag gatctacatc ttgggggcca agaatagatt tacttttaaa
     6541 acccgatgtt tcagcacctg gtaaaaatat taaatccacg cttaatgtta ttaatggcaa
     6601 atcaacttat ggctatatgt caggaactag tatggcgact ccaatcgtgg cagcttctac
     6661 tgttttgatt agaccgaaat taaaggaaat gcttgaaaga cctgtattga aaaatcttaa
     6721 gggagatgac aaaatagacc ttacaagtct tacaaaaatt gccctacaaa atactgcgcg
     6781 acctatgatg gatgcaactt cttggaaaga aaaaagtcaa tactttgcat cacctagaca
     6841 acagggagca ggcctaatta atgtggccaa tgctttgaga aatgaagttg tagcaacttt
     6901 caaaaacact gattctaaag gtttggtaaa ctcatatggt tccatttctc ttaaagaaat
     6961 aaaaggtgat aaaaaatact ttacaatcaa gcttcacaat acatcaaaca gacctttgac
     7021 ttttaaagtt tcagcatcag cgataactac agattcttta actgacagat taaaacttga
     7081 tgaaacatat aaagatgaaa aatctccaga tggtaagcaa attgttccag aaattcaccc
     7141 agaaaaagtc aaaggagcaa atatcacatt tgagcatgat actttcacta taggcgcaaa
     7201 ttctagcttt gatttgaatg cggttataaa tgttggagag gccaaaaaca aaaataaatt
     7261 tgtagaatca tttattcatt ttgagtcagt ggaagaaatg gaagctctaa actccaacgg
     7321 gaagaaaata aacttccaac cttctttgtc gatgcctcta atgggatttg ctgggaattg
     7381 gaaccacgaa ccaatccttg ataaatgggc ttgggaagaa gggtcaagat caaaaacact
     7441 gggaggttat gatgatgatg gtaaaccgaa aattccagga accttaaata agggaattgg
     7501 tggagaacat ggtatagata aatttaatcc agcaggagtt atacaaaata gaaaagataa
     7561 aaatacaaca tccctggatc aaaatccaga attatttgct ttcaataacc aagggatcaa
     7621 cgctccatca tcaagtggtt ctaagattgc taacatttat cctttagatt caaatggaaa
     7681 tcctcaagat gctcaacttg aaagaggatt aacaccttct ccacttgtat taagaagtgc
     7741 agaagaagga ttgatttcaa tagtaaatac aaataaagag ggagaaaatc aaagagactt
     7801 aaaagtcatt tcgagagaac actttattag aggaatttta aattctaaaa gcaatgatgc
     7861 aaagggaatc aaatcatcta aactaaaagt ttggggtgac ttgaagtggg atggactcat
     7921 ctataatcct agaggtagag aagaaaatgc accagaaagt aaggataatc aagatcctgc
     7981 tactaagata agaggtcaat ttgaaccgat tgcagaaggt caatatttct ataaatttaa
     8041 atatagatta actaaagatt acccatggca ggtttcctat attcctgtaa aaattgataa
     8101 caccgcccct aagattgttt cggttgattt ttcaaatcct gaaaaaatta agttgattac
     8161 aaaggatact tatcataagg taaaagatca gtataagaat gaaacgctat ttgcgagaga
     8221 tcaaaaagaa catcctgaaa aatttgacga gattgcgaac gaagtttggt atgctggcgc
     8281 cgctcttgtt aatgaagatg gagaggttga aaaaaatctt gaagtaactt acgcaggtga
     8341 gggtcaagga agaaatagaa aacttgacaa agacggaaat accatttatg aaattaaagg
     8401 tgcgggagat ttaaggggaa aaatcattga agtcattgca ttagatggtt ctagcaattt
     8461 cacaaagatt catagaatta aatttgctaa tcaggctgat gaaaagggga tgatttccta
     8521 ttatctagta gatcctgatc aagattcatc taaatatcaa aagcttggcg agattgcaga
     8581 atctaaattt aaaaatttag gaaatggaaa agagggtagt ctaaaaaaag atacaactgg
     8641 ggtagaacat catcatcaag aaaatgaaga gtctattaaa gaaaaatcta gttttactat
     8701 tgatagaaat atttcaacaa ttagagactt tgaaaataaa gacttaaaga aactcattaa
     8761 aaagaaattt agagaagttg atgattttac aagtgaaact ggtaagagaa tagaggaata
     8821 cgattataaa tacgatgata agggaaatat tattgcttat gatgatggta gtgccttaca
     8881 atatgaaact gaaaaacttg acgaaataaa atcaaaaatt tatggtgttc taagcccatc
     8941 taaagatgga cactttgaaa ttcttggaaa gataagcaat gtttctaaaa atgccaaggt
     9001 atattatgga aatagctata aatcgataga aatcaaagcg actaagtatg attcacattc
     9061 aaaaacgatg atatttgatt tatacgctaa tattaatgat attgtagatg gattagcttt
     9121 tgctggagat atgagattat ttgttaaaga tgacaatcaa ataaaagctg aaactaagat
     9181 tagaatgcct gaaaaaaata aggaaactaa agcagaatat ccctatgtat caagttatgg
     9241 gaatgtaatc gaattaggag aaggagatct ttcaaagaac aaaccagaca atttaactaa
     9301 aatggaatct ggtaaaatct attctgattc agaaaaacaa caatatctgt taaaggataa
     9361 catcattcta agaaaaggct atgcactaaa agtgactacc tataatcctg gaaaaacgga
     9421 tatgttagaa ggaaatggag tctatagcaa ggaagatata gcaaaaatac aaaaggccaa
     9481 tcctaatcta agagtccttt cagaaacaac aatttatgct gatagtagaa atgttgaaga
     9541 tggaagaagt acccaagctg tattaatgtc ggctttggac ggctttaaca ttataaggta
     9601 tcaagtgttt acatttaaaa tgaacgataa aggggaagct atcgataaag acggaaatct
     9661 tgtgacagat tcttctaaac ttgtattatt tggtaaggat gataaagaat acactggaga
     9721 ggataagtcc aatgtagaag ctataaaaga agatggctcc atgttattta ttgataccaa
     9781 accagtaaac ctttcaatgg ataagaacta ctttaatcca tctaaatcta ataaaattta
     9841 tgtacgaaat ccagaatttt atttaagagg taagatttct gataagggtg gttttaactg
     9901 ggaattgaga gttaatgaat cggttgtaga taattattta atctacggag atttacacat
     9961 tgataacact agagatttta atattaagct gaatgttaaa gacggtgaca tcatggactg
    10021 gggaatgaaa gactataaag caaacggatt tccagataag gtaacagata tggatggaaa
    10081 tgtttatctt caaactggct atagcgattt gaatgctaaa gcagttggag tccactatca
    10141 gtttttatat gataatgtta aacccgaagt aaacattgat cctaagggaa atactagtat
    10201 cgaatatgct gatggaaaat ctgtagtctt taacatcaat gataaaagaa ataatggatt
    10261 cgatggtgag attcaagaac aacatattta tgtaaatgga aaagaatata catcatttga
    10321 tgatattaaa caaataacag acaagacact aaacattaag attgttgtaa aagattttgc
    10381 aagaaataca accgtaaaag aattcatttt aaataaagat acgggagagg taagtgaatt
    10441 aaaacctcat agggtaactg tgaccattca aaatggaaaa gaaatgagtt caacgatagt
    10501 gtcggaagaa gattttattt tacctgttta taagggtgaa ttagaaaaag gataccaatt
    10561 tgatggttgg gaaatttctg gtttcgaagg taaaaaagac gctggctatg ttattaatct
    10621 atcaaaagat acctttataa aacctgtatt caagaaaata gaggagaaaa aggaggaaga
    10681 aaataaacct acttttgatg tatcgaaaaa gaaagataac ccacaagtaa accatagtca
    10741 attaaatgaa agtcacagaa aagaggattt acaaagagaa gatcattcac aaaaatctga
    10801 ttcaactaag gatgttacag ctacagttct tgataaaaac aatatcagta gtaaatcaac
    10861 tactaacaat cctaataagt tgccaaaaac tggaacagca agcggagccc agacactatt
    10921 agctgccgga ataatgttta tagtaggaat ttttcttgga ttgaagaaaa aaaatcaaga
    10981 ttaagacaaa agctatagaa aaaaatggtt tatgtactga gattagatag tgaggtgatg
    11041 acatagtttt gtgaaaacgg ccatttataa ctcaattatt tagtttactt cacttcacta
    11101 ttgatactat ttggagttat taatggactt agtttagata actaatgaat tgattgaaag
    11161 ggttagtatt gacaatattg gtcatattga ttagaaaata gagtctatca aaatttaaag
    11221 gctaatagag gtgatgagac aatttcaagg aattaagtag cgtttggttg cttaattcct
    11281 ttttatttgg aaggaagttt ttcgtaaccg cccaataacg aagtctattg gacggttacg
    11341 atatgatcac tgacttcgtc agtcttatct acaacctcaa aactgtgttt tgagcaacct
    11401 gcggctagct tcctagttta ctctttgatt ttcattgagt attagaacag aaaaaatgct
    11461 tggagtattt gtttgtgtgt ttatttttat ataacaaact ataaacaaaa caaaaatata
    11521 aaaaaagaga caaaaaagaa tagaaagtaa ttaacaacga tttcatatag tgttatactt
    11581 atagcataaa gttaatggaa agaagggaaa accttatggt attagattat ttctttgaca
    11641 aaaaccttgt gttttgctta gaagcggata atcaagaata actttttgat caggtagcaa
    11701 gcttgttgga agaacgagaa attgtcactc caacttatcg tgaagccttg atcacgcgtg
    11761 aaaagtcatt tccaactggt ttagatatgg aatttctagg aaaggacttg caaatgtaat
    11821 gattcctcac acagatattg ttcataatct agctgagaaa gtggtggttg ttcgattaga
    11881 gaaaccggtg actttccata atatgattgc gccaggtaag gaagtagaag tatccttgct
    11941 cttctttatc atcaataatt caagttcaag tcaaacgaac attcttgctc agttgatgga
    12001 ctttttcaca ggaaatggac atcttgaaga cctatcaaaa atttccgaac cagaaaaact
    12061 ttatgcttat atagatgaag caatcgctta atcttgtcta ttaaaaaata aaatcggagg
    12121 aagtctatat gattaaaatt cttgctgcct gcggtgcagg tgttaactca agtcaccaaa
    12181 ttaaaagtgc tctagaagaa gaactttcaa accgtggtta tgatgttcac tgtgatgcag
    12241 ttatggtgaa agatgtaaac gaagacctta tgaaaggtta cgatatcttt acaccaatcg
    12301 ctgcaacaga ccttggtttt gaaccaggta tcccagttat cgaagctggg ccaatcttat
    12361 tctgtatccc agcaatgagc gttccagtat ttgacaatat tagacttcct gcgaaacaaa
    12421 atatggtata gtagttccat gaattatgaa gcaagtaaac aactaactga tgcacgattt
    12481 aagcgtcttg ttggtgttca acgcacgact tttgaagaga tattagctgt attaaaaaca
    12541 gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta aattaagcct agaagacttt
    12601 cttatggcca ctcttcaata tgtgcgagaa tatcgaactt atgaagaaat tgcggctgat
    12661 tttggtatcc acgaaagcaa cttaatccgt cggagccgat gggttgaagt aactcttgtt
    12721 caaagtggtg ttacgatttc aagaactcct ctcagttctg aggacacggt aatgattgat
    12781 gcgacggaag tacaaatcaa tcgccctaaa aaaacaatta gcgaattatt ctggtaaaaa
    12841 gaaatttcac gctatgaagg ctcaagcgat tgtcacaagt caagggagaa ttgtttcttt
    12901 ggatatcgct gtgaactatt gtcatgatat gaagttgttc aaaatgagtc gcagaaatat
    12961 cggacaagct ggtaaaatct tggctgacag tggttatcaa gggctcatga agatatatcc
    13021 tcaagcacaa attccacgta aatccagcaa actcaagccg ctaatagctg aagataaagc
    13081 ctataaccat gcgctatcta aggatagaag caaggttgag aacatctttg ccaaagtaaa
    13141 aacgtttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat
    13201 gaatttgagt gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctaa
    13261 taaagaaact agcaaggtca ggccttactt tattggtgga catccaggat ttaattgtct
    13321 tctacttgat gatgaagtct atgaagatta ttatctagag tttgagaaag aagagatttg
    13381 ctctgttcca cgtcctttcc cagaaacagg tatgttggat ttccaagata gaagtccatg
    13441 gctagaggga caaaaagaaa tagatcttag ttatgatctt ttcagcacag atgcagtgac
    13501 tttggatgaa ttgcaatctc gaacaattgc ccttcgttct cttaagcatg ataagggatt
    13561 gaaagtgcat tttgcagaat ttccaaacct catcatctgg tcaactttga acaagggacc
    13621 tttcattacc tttgaaccat ggtctggctt gtcaacattc cttgaagaag gagatcattt
    13681 agaagataag aagaatgttt gtctcttaga agccaatcag gttgaagaat tagggtttga
    13741 gatagaagtt ttataaaaaa agtaaaaaat aaataacaaa aacaaacaca aactgttgac
    13801 ttcttcaaac aatagtagta tattatgttt gtgaggacta attgactgtt ttttaaagac
    13861 agccaataca ctgctggaat ccagcataga aaaaataaaa aggagtatac aatatgtcta
    13921 ttgttatcgg tgcagatgct gcaggtttga gattgaaaga agttgtgaaa gacttcttag
    13981 aaaaagaaaa cttccacctt gtggatgtta cagctgaagg tcaagacttt gttgatgtga
    14041 ctctcgctgt tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc gtgattgatg
    14101 cttatggagc tggtccattt atggttgcaa ctaagatcaa aggaatggtt gctgcagaag
    14161 tatctgacga acgttcagct tatatgactc gtggccacaa caactcacgt atgatcacta
    14221 tgggtgcaca acttgttggt gatgaattgg ctaaaaacat cgctaaagga tttgttaacg
    14281 gtaaatacga tggtggacgt catcaaatcc gggtcgacat gttgaacaaa atgggctaat
    14341 tagattacag taagaaaggt aagttaaaaa tgagaattgc aattggatgc gaccacatcg
    14401 taacagatga aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat gaagtcattg
    14461 actttggtac atatgaccat acacggactc actacccaat ctttggtaaa aaagtagggg
    14521 aagctgtaac tagcggccaa gctgatcttg gggtatgtat ctgtggtact ggtgttggta
    14581 tcaacaacgc tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt gatatgacaa
    14641 cagcccttta tgctaaagaa caattgaacg ctaacgttat cggctttggt ggtaagatta
    14701 ctggtgaatt gcttatgtgt gatatcatcg aagctttcat tcatgctgaa tacaaaccat
    14761 ctgaagaaaa caagaaattg attgcgaaaa ttgaacacct tgaaagtcac aatgctcaac
    14821 aaacagacgc aaacttcttt acagaattcc ttgaaaaatg ggatcgcgga gaataccacg
    14881 actaagaggt gacctatgat tttaacagtc acaatgaacc catccattga tatttcctat
    14941 cccttggatg agttgaagat tgatactgtc aatcgtgtgg tggatgtaac caaaacggct
    15001 ggtggtaagg gactcaatgt tacccgagta ctttcagaat ttggcgattc tgttcttgct
    15061 actggtttag tgggtggcaa acttggtgag tttttggttg aacatatcga taatcaagta
    15121 aagaaagatt tcttctcaat tcagggagaa actcgtaact gtatcgctat tctccacgga
    15181 gacaaccaaa cagaagttct tgaaaaaggt cctgaagtat tggaacagga aggtcaagac
    15241 tttttggaac atttcaaaaa actcttggag tcagttgaag tagtggccat ctcaggtagt
    15301 ctgccagctg gccttccagt tgattactat gcgagcttgg tagaacttgc taatcaagct
    15361 ggcaagcctg tagtcttgga ctgctcaggt gcagcacttc aggctgttct tgaatcaccc
    15421 cataaaccaa cagtcatcaa accaaataat gaagaattgt ctcagcttct tggaagagaa
    15481 gtttctgagg atttggatga attaaaagaa gtacttcaag aacctttgtt tgcagggatt
    15541 gaatggatta tcgtttcact tggtgccaac ggtacttttg ccaaacatgg tgacactttc
    15601 tacaaggtag atattcctag aattcaggtg gtaaatcctg ttggatctgg agactctact
    15661 gtggcaggaa tttcttcagg acttcttcac aaagaatcgg atgcagaatt actcatcaag
    15721 gcaaatgtcc ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt caacatggcc
    15781 aactatcaag ctctatatga tcaattaata gtaaaagagg tataaaatgg ctttaacaga
    15841 acaaaaacgt gtacgcttag aaaaactttc tgatgaaaat ggtatcatct cagctcttgc
    15901 atttgaccaa cgtggtgctt tgaaacgcct catggctcaa caccaaacag aagaaccaac
    15961 tgtggcccaa atggaagaac ttaaagtctt ggtagcagat gaattgacta aatacgcttc
    16021 atctatgctt cttgaccctg agtatggact tccagcaact aaagctcttg atgaaaaagc
    16081 tggtcttctc cttgcttatg aaaaaacagg ttatgacaca acaagcacaa aacgcttgcc
    16141 agactgcttg gatgtttggt ctgcaaaacg tattaaagaa gaaggtgcag atgcagttaa
    16201 attcttgctt tactatgatg tagatagctc agacgaactc aatcaagaaa aacaagccta
    16261 catcgaacgc atcggttctg agtgtgtggc tgaagatatc ccattcttcc ttgaaatcct
    16321 tgcttacgat gaaaaaattg cggatgcagg ttctgtagaa tacgcgaaag taaaaccaca
    16381 caaagttatc ggcgctatga aagtcttttc agacccacgc tttaacattg atgtcttgaa
    16441 agttgaagtt cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg aagtagttta
    16501 tacacgtgaa gaagcagcag ccttcttcaa agcgcaagat gaagcaacga acttgccata
    16561 catctacttg agtgctggtg tatcagctaa actcttccaa gatactcttg tatttgctca
    16621 tgaatcaggt gcaaacttta acggagttct ttgtggccgt gctacatggg cagggtcagt
    16681 tgaagcttac atcaaagatg gtgaagcagc agctcgcgaa tggcttcgca caactggatt
    16741 tgaaaacatt gatgagctca ataaggttct tcaaacaaca gcgacttcat ggaaagaacg
    16801 tgtgtaagaa agtcctccta gtttaggaac atgaatctaa aaaaatttaa aaaaagttgt
    16861 atgtaaaggt ttacaaaata acttacttgt gctatactta aatcacaagt taatacaagg
    16921 tgagtgttac taagtaatat taggcatgat cacaggtgaa ttagaaatca gctgattttc
    16981 tagttcattt gtggtcattt tttgtactca tataccttta aaatataaaa ggaggttgac
    17041 atgtatcgaa ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa tgataaggga
    17101 gaagaggtga ttgtaattgg taaggggatt gcattcggaa agaagaaggg ggatttgatt
    17161 gctgaaaatc aggttgagaa aatctttcgg atgaagaccg aagagtccag agaaaacttt
    17221 atggctcttc tcaaagatgt tccgcttgat tttatcacag tgacctatga aatcattgat
    17281 aagctatcaa agaaatatca ttatccgatt caagagtatc tctatgtaac cttgacagat
    17341 catatttact gttcttatca agctctaact caaggaaggt acaaggatag taatctgcca
    17401 gatatttccg ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt tgaaatttac
    17461 cgtcagaagc tagcagatca ttttcctgag gacgaaatta ttcggattgc ttatcatttc
    17521 attaatgctg aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa gaggaaagaa
    17581 attctcagga atgttgaaga agttttaacg gactatgcaa ttcaacgaac taaaaagaat
    17641 aaccatttct atgatcgctt tatgatccat ttgaattatt tcttggatta tttagacaga
    17701 tctagagatg ataaccaatc acttctggat atggaagatc atattaaaca atcctatcca
    17761 aaagccttcg agattggttc caagatctat gatgtgatta cgcaacatac gggtcttgat
    17821 ttgtataaaa gtgaacgagt ttatctagtt ctacatatcc aacgtttatt gtcataaaaa
    17881 tttatttaaa actatataag gagaattcta tcatgaatag agaagaagta acattgttag
    17941 gttttgaaat cgtagcctat gctggcgatg ctcgttcaaa actattggaa gccttgaagg
    18001 ctgctgaagc tggtgatttt gaaaaagcgg acgctctggt agaggaagct ggtagctgta
    18061 ttgcagaggc tcaccacgcg caaacaagtc tattgactaa ggaagcttct ggtgaggact
    18121 tagcgtatag tgtgaccatg atgcatggtc aagatcactt gatgacaact atcttgttaa
    18181 aagacctaat gcaccattta attgaacttt acaagagagg agttaaataa aatggataag
    18241 ttaataattt ttattgagaa aggaaagcct ttctttgaaa aattatcgag aaatatatac
    18301 ttaagagcga taaaagatgg ttttatttcc agtatgccag cagtattatt ctcaagtatt
    18361 tttatactaa tagctgctgt gcccaatatt tttgggttta aatggtctga tgaacagtta
    18421 gcttttattt tgaaacctta caactactca atgggaattt tagctctctt agtagctggg
    18481 acaactgcaa aatcgttaac agattcagtt aatacacgta gtatggagaa aaccaaccaa
    18541 atcaactaca tgtcaacttt tttagcagct gttgttggat tgttaatact ggcagctgat
    18601 ccaattgaag gtggatttgc taatggtctt ttaggtacta gaggattact tactgcattt
    18661 ttggcagctt ttattacagt aaatatctat aaagtatgta ttaaaaataa tgtaaccatt
    18721 agacttcctg aagaggttcc accaaatatt gcacaagttt ttaaagatgt tattccgttt
    18781 gccttatctg ttctttcaat atatggattg gatttaattg ttagaaatat ttttggtaca
    18841 aatgtagcag aatctgttgg taaaatatta gcccctctat tttcagctac tgatggttat
    18901 atcggtttag ctattgtatt tggtgcttat gctttctttt ggtttgttgg aattcatggg
    18961 ccatctgttg tagaaccttt aattgtagct atcagttatg caaatataga agctaatgtt
    19021 cagcttgtgc aagctggtat gcacgcagat aaaattttaa atccagttac tcaaactttt
    19081 gttgtaacaa tgggtggtac tggtgcaaca ctagtagttc catttatgtt tatgtggtta
    19141 tgtaaatcaa aaagaaatag aattgtcgga cgtgcgtctg tagttcctac tttctttggc
    19201 gtaaatgaac caatcctatt tggtgctcca attgttttaa atcctatctt ctttattccg
    19261 tttgttactg ctcctattat caatgtttgg attatgaaat tttttgtaga tgttctacaa
    19321 atgaatagtt tcagtattat tttaccttgg acaacacctg ctccaattgg tattgttatg
    19381 ggaacggcgc tggctccatt gtcattcgtc ttggctataa ctttaatcat tatcgacact
    19441 ttaatctatt atccatttgt taaagtttat gaccatcaaa ttttagaaga agaacggaaa
    19501 ggaaactctt catctgaatt gaaagaaaaa gttgctgcaa acttcaacac tgcaaaagcg
    19561 gatgctattc ttgaaaaagc gggtgtcgat gcagcacaaa ataccatcac tgaagaaaca
    19621 aatgtcctcg ttctctgtgc tggtggaggt acaagtggac tccttgcaaa tgctttgaat
    19681 aaggcagcag cagaatacaa tgtccctgtg aaagcagcag caggtggcta tggtgctcac
    19741 cgtgaaatgt tgccagagtt tgatcttgtt atccttgccc ctcaagttgc ttcaaacttt
    19801 gaagatatga aggcagaaac agataagctc ggtattaaac ttgctaagac agaaggcgct
    19861 caatacatca aattaactcg tgatggaaaa ggtgccctag cattcgtaca agagcaattc
    19921 gattaaggct agagactctg aaacagtctc ccatcgttac ggaaatcgct atggcgaatt
    19981 tcctaatcgc cttattaatt cgtcggtaaa aagatatcgt ttttacctcc tcatgtcaca
    20041 attcggtgac ttggtacaag aagtgagatg gagaaggatg gctcactgac tcctctcctc
    20101 tcacttttac tttatttaaa tcaagaaata ggtgaaaaaa atgacaaaaa cacttccaaa
    20161 agactttatt tttggtggcg caacagctgc ctatcaagca gaaggtgcta cacatactga
    20221 tggtaaagga ccagtagcgt gggataaata tcttgaagat aactactggt acactgcaga
    20281 accagccagt gatttttaca atcgatatcc agttgacctc aagctagcag aagagtatgg
    20341 tgtcaatggt attcgaattt ctattgcttg gtcacgtatt ttcccgactg gttacggcca
    20401 agtaaatgct aaaggtgttg agttttatca taatttattt gcagagtgtc acaaacgtca
    20461 tgttgagcct tttgtaactc ttcatcactt tgacacgcca gaagctctcc actcaaatgg
    20521 agacttctta aaccgtgaaa atatcgaaca ttttgtagac tacgctgcct tctgttttga
    20581 agaatttcca gaagtaaact attggacaac ctttaatgaa attggaccaa tcggtgatgg
    20641 tcaatatttg gttgggaaat tccctccagg tatccagtac gaccttgcca aagtctttca
    20701 atcacaccac aatatgatgg tgtctcatgc acgcgcggta aaattgtaca aagagaaagg
    20761 ctataaaggg gaaattggtg ttgttcacgc cctgcctact aaatatcctc tagatcctga
    20821 aaatccagca gatgttcgtg cagcagagtt ggaagatatc atccacaata aattcatctt
    20881 agacgcaact tatctaggtc gctattcagc tgaaaccatg gaaggtgtca accatatctt
    20941 atcagtcaat ggtggtagtt tggatcttcg tgaagaagat tttacagcat tagaagctgc
    21001 aaaagacttg aatgatttcc taggaatcaa ctactatatg agtgactgga tggaagcctt
    21061 tgatggagaa actgaaatta tccataatgg taaaggtgaa aaaggaagct ctaagtatca
    21121 aatcaaaggt attggtcgtc gtgtagctcc tgactatgta tcacgcacgg attgggattg
    21181 gattatctac cctcaaggtt tgtatgacca aatcatgcgt gtgaagaaag attatcctaa
    21241 ctacaagaaa atttatatca ctgaaaatgg tctcggctat aaagatgagt tcgttaataa
    21301 cactgtttac gatgatggtc gtattgatta cgtgaaacaa cacttggaga tcttgtctga
    21361 tgcgattgca gatggagcta atgtaaaagg ttacttcatt tggtcattaa tggatgtctt
    21421 ctcatggtca aacggttatg agaaacgtta tggtcttttc tacgtagatt ttgaaactca
    21481 agaacgttat cctaagaaat cagctcactg gtacaagaaa gtagcggaaa ctcagattat
    21541 agactagtag aattagtcat tagatataga attttagtga gtcaaaaaga tgttcaaaga
    21601 ttttatccaa tctatttatg aaaaagttta tattataaat ttcgaaaaat actctcaaat
    21661 accgtgtttg acgagtgaag aattgaaaag tcttggaaaa tggtatgtct cgactggtaa
    21721 agaatggatt tgtcattcag atgatgatct ggaagaattt aaaaatctat ttttaaattt
    21781 tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc tgtttcaaca
    21841 atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgta aaactcttat
    21901 ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta ggaagcgagt
    21961 cgcagatttc tcaatgtata gctttgagga attgggcaaa aagtctttga tatagaaaaa
    22021 agcatagtat caggtgtttc aacacctgat actatgcttt ttattgtggg aagatttact
    22081 ttttttcttc tgaaattgag ttgttaccca ggctctttca gtttattaag gcttgatgac
    22141 tttaatgtgt ttagatagct taaaaaggat tgaatcactt agtttagaat ctgaaacaat
    22201 agtatcaaga tttgatatat tataaaaagt ataaaaatca aacttattga acttactatg
    22261 atctgcgagt aaatattttt tattagaatt atttaaagcg atgcgttgag cctctccctc
    22321 ttcctcgcta aaagtagcta gagctccgtt ttgaatacca ttacagctaa cgaaagcttt
    22381 agaaaattgg agattagaga gattttgtag ggtcaatgtg ccaacaaaag cacctgtaat
    22441 atcgcgataa tttccaccta tcaaaatcaa atctgttaat tttcgttcgc ttaaaatcag
    22501 aaaaacaggt agactgttgg ttacgacgcg gatattgtca ataggcaact cacgcgcaaa
    22561 aaactctaat gttgttcctg gtccaatgaa aatagtttct ctttcttcta ctagactgcc
    22621 tgcaaaatgg gctatttctt gtttttctgc cgtttggagg gcttgttttt caatatttga
    22681 tcgctcatta gtcaaaaggg agttggttcg aagtttttca gctccaccat gcacacgaat
    22741 cagcaaatct ttatcagcta attcctgtaa atagcgcctt gcagtcatat ctgaaacggc
    22801 tatttcgtcc ataatctgtt taactgttat ggttccttta ctatttacta tctctaaaat
    22861 tttggttaat ttttcttgtt tgagcatatt atcacctcgt ttcctactac tatcttacca
    22921 taaacaaact catcattcaa atacaaaaac aacaaaatga aacaaaaaca aaaatatcga
    22981 agtttgtttt caaaactttc gatatttttg ttgggttata actttgatgt ttctagttta
    23041 ctttttgatg attgagagtg atggagaatt agtctaaacc gtagttatag tcatcgtctt
    23101 gcatggcttc aacttcgcca agaaggtaac catttccgac ttgagagaag aagtcatggt
    23161 tggaagttcc tgttgaaata ccgttcataa cgattgggtt gacatcttca gctgaatctg
    23221 ggaaaagtgg atcttgtccc atgttcatga gagctttatt ggcattgtag cgaaggaagg
    23281 ttttaacctc ttcagtccaa ccaacaccgt cataaagact ctctgtgtag ccttcttcat
    23341 tttcataaag agtatagagt aggtcgtaca tccattcttt gagtttttct tgctcttctt
    23401 caggcaattc attgaaacca agttggaatt tgtaaccaat gtaggttccg tgaacagact
    23461 cgtcacgaat aatcaattta atgatttctg caacgttggc tagtttgttg ttaccgagat
    23521 agtagagggg agtgaagaaa ccagagtaga agaggaaggt ttcgaggaag acgctggcaa
    23581 ctttcttttc aagtgggctg ccgtttaggt agatttcgtt gacaatctca gccttctttt
    23641 gtaggtaagg attggtattg gtccattcga aaatttcttc aatctcagcc ttagtattca
    23701 aggtagaaaa gattgatgag taagatttag cgtggacaga ttccataaat tggatgttat
    23761 tgaaaacagc ttcctcatgt ggtgtacgga tgtctgcgcg aagggcttga accccagttt
    23821 cagattgcat agtgtcaaga agggttaaac caccaaaaac ttttccgacc aagtctttct
    23881 ctttgttaga tagctttctc cagtcatcca agtcgtttga taagggaata cgtgtatcga
    23941 gccaaaattg ctccgtcagt ttttcccaag ttgatttgtc gatgacatct tcgatggcat
    24001 tccagttaat ggctttgtag taagtttcca tttaaaatct ctttctgtgt ttagtattgc
    24061 gaactcacaa ttatttctac tttaccataa ttctatagga gtatcgcaca aaaagtcgga
    24121 agcccgactt ttaaaatgtt acataaatta tgttatgaca tagtagattt gattttatct
    24181 gtgctgctta gggaaaaata atgtttctat gctagaaact aaatcacaca gctttcacat
    24241 tggttggcgc cgacttctcc accgtcatct gtaaaggtac ggacgtagta gatagacttg
    24301 attcccttgt taaaggcata gttacgaagg atggacaagt cacgtgtcgt ttgtttattt
    24361 tccctcttcc attcgtaaag gccttttgga atgtcactac gcatgaagag ggtgagtgaa
    24421 agtccttgat ccacgtgttc agtcgcagca gcgtaaacat cgatgacttt acgcatatcc
    24481 atatcgtagg cagaagtgta gtaaggaatg gtttctgtag acaagccagc agcagggtag
    24541 tagattttac caattttctt ctcttggcgt tcttcgatac gttgcgtaat cgggtggata
    24601 gaagcagaaa cgtcgttgat atagctgata gaaccatttg gcgctacagc aaggcgattt
    24661 tggtggtaaa gaccatcttc ttgaaccttg tcgcgaagtt cagcccaatc agcaacacca
    24721 gggataaaga catttttgaa gagttcttta acacggtctg atgttggaac aaattcacca
    24781 gttacatact tgtcaaagta acttccgtta gcatagtctg atttttcaaa gttgtggaag
    24841 gtaataccac gttcacgcgc aatattgttt gactctacca aggtccagta gttcataagc
    24901 ataaagtaga tgcttgtaaa ttcaacagac tcaggtgaac catattcaat gagttgttgg
    24961 gcaaggtagc tgtgcagtcc catggcaccg agaccaaagg tgtgggcttg gctatttcca
    25021 tggtcaatcg ttggtacagc tacgatatgt gaactatctg taacgaaagt aagggcacga
    25081 accatagcac ggatagaacg accaaaatca ggtgaagtca tcatgttaac cacgttggtt
    25141 gaacccaggt tacatgaaac atctgttccc atttgaagga attcttgagc atcgttgatc
    25201 aagcttggtt cttgaacttg aagaatctca gaacacaagt tactcatgat aatctttcca
    25261 tcaacaggat ttgcacggtt agccgtatct atgttgacta cataaggata gccagactct
    25321 tgttgcaatt tagagatttc agtttccaaa tcccgcgcct tgatttttgt cttgcgaata
    25381 tttggatttg cgaccaattc atcgtatttt tcagtaatgt cgatgtaatt gaatggcaca
    25441 ccgtattctt tttctacaga gtaagggctg aagaggtaca tttcttcatt tttacgagcc
    25501 aattcgtaga atttatcagg tactacaaca ccaagtgata gagtcttgac acgtactttt
    25561 tcatcagcgt tttctttctt agttgaaagg aaagcgatga tatctgggtg aaagacgttg
    25621 aggtagacaa caccggcacc ttgacgttgc cccaattggt tggagtaaga gaagctgtct
    25681 tcaaaaagct tcataacagg aacgacacct gaagcagctc cttcatagcc tttgataggt
    25741 gcaccagctt cacgaaggtt gctgagggta attcccacac caccaccaat acgtgaaagt
    25801 tgaagagctg agttgataga acgtccgata gagttcatat catccgtcac ttggattagg
    25861 aaacaagata ccaactcccc acgacgagca cgtccagcat tcaagaagga aggagtagca
    25921 ggttggtagc gttggtggat gatttcattg gcaatatcga ttgcaacagc ttcattccca
    25981 tcagcgaaat aaagggcgtt gaagaagaca cggtcttcca tattttcaag atagtattca
    26041 ccgtcattag tctttaaggc atattgattg taaaatttat aagctgccat gaatgacttg
    26101 aattggaagt tttggtcttt gataaattga gccaattctt ccaagaactc tggacggtat
    26161 ttcttgataa aggctgtttc gatgtagttg tgttcaatga ggtaattgat tttgtctttg
    26221 attgaatcaa aaaccatagt gtttggaact acattttctt taaagaaagc atccaaggct
    26281 tccttatctt tatgaagcat gatttgtcca ttaacaggac ggttaatttc gttattaaga
    26341 cggaagtaag tcacgtcttc aagatgtttt aatcccataa aatttccctt atctaattac
    26401 aaaagaaagg cttctaagtt agccctaaaa gcagtttctt ctggatgatg tacataagat
    26461 tatgctaatt gtttcagttt tcctggttgg aaacctgaaa agacttcagt tggtgtttgg
    26521 ataacaggag ctgcgctaaa accgagctct ttaacttgat cgacgtactc aggttgctca
    26581 tcaagattga tttcacgata agagacatta ttactgtcca agaaacgctt ggtcatttta
    26641 cattggacac aattgttttt agaataaacg gttaccattg tgtaactcct cttcaaaatt
    26701 taatactatc ttagtatatc agaaaataaa attttgtcaa tgatttgaac taaatatagt
    26761 ggtgttcttt tgttgttttt atatataaac acaatatata gtgtttatat tgtgaaatag
    26821 caatgattat cctataaatt gtttttgaag aaactatatc ctgtgttttg ttatctagga
    26881 tagaagattt tcagcaagtt atctgaaagg aaattgaagg aaaatccaga aaatgcttga
    26941 aaaaaatcct agaagatggt ataatactaa attgtaaggg ttatcacata taactcaaaa
    27001 aaagaaagaa caaaaggaga gtcaaactat ggcttctaaa gatttccacg tagtggcaga
    27061 aacaggtatt cacgcacgtc cagcaacatt gttggtacaa actgctagca aatttgcttc
    27121 agatatcact cttgagtaca aaggtaaatc agttaacctt aaatcaatta tgggtgttat
    27181 gagtcttggt gttggccaag gtgctgacgt aactatctca gctgaaggtg cagatgcaga
    27241 tgacgctatc gctgcaatct cagaaacaat ggaaaaagaa ggattggcat aagggaaatg
    27301 acagaaatgc ttaaaggaat cgcagcatct gacggtgttg cagttgcaaa agcatatcta
    27361 ctcgttcagc cggatttgtc atttgagact attacagtcg aagatacaaa cgcagaagaa
    27421 gctcgccttg atgccgctct acaggcatca caagacgagc tttctgttat tcgcgagaaa
    27481 gcagtaggta cgctcggtga agaagcagct caagtttttg aagctcactt aatggttctt
    27541 gctgatccag aaatgatcag ccaaatcaag gaaactatcc gtgcgaagaa agtgaatgca
    27601 gaagcaggtc tgaaagaagt tacagatatg tttatcacta tctttgaagg catggaagac
    27661 aacccataca tgcaagaacg cgcagcggat atccgcgacg tgacaaaacg tgtattggca
    27721 aaccttcttg gtaagaaatt accaaaccca gcttctataa atgaagaagt gatcgtgatt
    27781 gcacatgact tgacaccatc tgatacagct caattggaca aaaactttgt aaaagctttt
    27841 gtaaccaaca ttggtggacg tacaagccac tcagctatca tggcacgtac acttgaaatt
    27901 gctgctgtat taggtacaaa caacatcact gaaatcgtta aagacggtga catccttgct
    27961 gttaacggga tcactggaga agtgattatc aacccaacag atgaacaagc ggcagaattt
    28021 aaagcagctg gtgaagctta tgcgaaacaa aaagctgaat gggcactttt gaaagatgct
    28081 caaacagtga ctgctgacgg taaacacttc gagttggctg ctaatatcgg tactccaaaa
    28141 gacgttgaag gtgttaacaa caacggtgca gaagctgttg gactttaccg tacagagttc
    28201 ttgtacatgg attctcaaga cttcccaact gaagatgagc agtatgaagc atacaaggct
    28261 gttcttgaag gaatgaacgg taaacctgtt gtcgttcgta caatggatat cggtggagat
    28321 aaggaacttc cttacttcga tatgcctcac gaaatgaacc cattccttgg attccgtgct
    28381 cttcgtatct ctatctctga gactggagat gctatgttcc gcacacaaat ccgtgctctt
    28441 cttcgtgcgt ctgttcacgg tcaattgcgt atcatgttcc caatggttgc gctcttgaaa
    28501 gaattccgtg cagcgaaagc agtctttgat gaagaaaaag caaaccttct tgctgaaggt
    28561 gttgcagttg cggataacat tcaagttggt atcatgatcg agatccctgc agcggctatg
    28621 cttgcagacc aatttgctaa agaagttgac ttcttctcaa ttggtacaaa tgacttgatc
    28681 caatatacaa tggcagcaga ccgtatgaac gaacaagttt cataccttta ccaaccatac
    28741 aacccatcaa tcctacgctt gattaacaat gtgatcaaag cagctcacgc tgaagataaa
    28801 tgggctggta tgtgtggtga gatggctggt gaccaacaag ctgttccact tcttgtcgga
    28861 atgggcttgg atgagttctc tatgtcagca acatctgtac ttcgtacacg cagcttgatg
    28921 aagaaactcg acacagctaa gatggaagag tacgcaaacc gtgcccttac agaatgctca
    28981 acaatggaag aagttcttga acttcaaaaa gaatacgtta attttgatta atcgaaaagt
    29041 ccctgcaact cagttacagg gacttttttg atattttaaa aagaattttc aagaaaatct
    29101 ttcttataga aagtccaacc ttgaaaaagt agtagtcaga acaaaaaata cttaaatggt
    29161 tcataaaatt cttgacaagt tggagattta ggagtaaact attaaccagt taagtaatag
    29221 agaggagttt ctgcaattta gaaatgaatt gcaactagaa atatcaaata gaaagagagt
    29281 ttcgatgaaa attaataaga aataccttgt tggttctgcg gcagctttga ttttaagtgt
    29341 ttgttcttac gagttgggac tgtatcaagc tagaacggtt aaggaaaata atcgtgtttc
    29401 ctatatagat ggtaaacaag cagcacaaaa aacggagaat ctgactcctg atgaggtcag
    29461 taaaaaagaa ggtatcaatg ccgaacaaat cgtcatcaag ataacagacc aaggctatgt
    29521 gacttcacat ggggaccact atcattatta caatgggaag gttccttatg acgctatcat
    29581 cagtgaagaa ttgctgatga aggatccaaa ctaccagcta aaagacgagg atattatcag
    29641 tgaaatcaag ggtggttatg ttatcaaggt agatggaaaa tactatgttt accttaagga
    29701 tgctgcccac gcggataatg tccgtacaaa agaagaaatc aatcggcaaa aacaagaaca
    29761 tagtcagcat cgtgaaggag ggacttcagc aaacgatggt gcggtagcct ttgcacgttc
    29821 acagggacgc tacaccacag atgatgggta tatcttcaat gcatctgata tcattgagga
    29881 cacgggtgat gcttatatcg ttcctcacgg cgaccattac cattacattc ctaagaatga
    29941 gttatcagct agcgagttgg ctgctgcaga agccttccta tctggtcggg aaaatctgtc
    30001 aaatttaaga acctatcgcc gacaaaatag cgataacact ccaagaacaa actgggtacc
    30061 ttctgtaagc aatccaggaa ctacaaatac taacacaagc aacaacagca acactaacag
    30121 tcaagcaagt caaagtaatg acattgatag tctcttgaaa cagctctaca aactgccttt
    30181 gagtcaacgc catgtagaat ctgatggcct tattttcgac ccagcgcaaa tcacaagtcg
    30241 aaccgccaga ggtgtagctg tccctcatgg taaccattac cactttatcc cttatgaaca
    30301 aatgtctgaa ttggaagaac gaattgctcg tattattccc cttcgttatc gttcaaacca
    30361 ttgggtacca gattcaagac cagaagaacc aagtcc
//
LOCUS       DAVLHB010000023        29152 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLHB010000023 DAVLHB010000000
VERSION     DAVLHB010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.023"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(498..590)
                     /locus_tag="VXE36_001151"
     CDS             complement(498..590)
                     /locus_tag="VXE36_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0779464.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            751..1722
                     /gene="ruvB"
                     /locus_tag="VXE36_001152"
     CDS             751..1722
                     /gene="ruvB"
                     /locus_tag="VXE36_001152"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0779465.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1703..2275
                     /locus_tag="VXE36_001153"
     CDS             1703..2275
                     /locus_tag="VXE36_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0779466.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLKKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2506..3264
                     /locus_tag="VXE36_001154"
     CDS             2506..3264
                     /locus_tag="VXE36_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0779467.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3273..4076
                     /locus_tag="VXE36_001155"
     CDS             3273..4076
                     /locus_tag="VXE36_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0779468.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4098..5357
                     /gene="rseP"
                     /locus_tag="VXE36_001156"
     CDS             4098..5357
                     /gene="rseP"
                     /locus_tag="VXE36_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0779469.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETSQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5370..7223
                     /locus_tag="VXE36_001157"
     CDS             5370..7223
                     /locus_tag="VXE36_001157"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0779470.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7322..8701
                     /gene="bglA"
                     /locus_tag="VXE36_001158"
     CDS             7322..8701
                     /gene="bglA"
                     /locus_tag="VXE36_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0779471.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            8893..10701
                     /gene="glmS"
                     /locus_tag="VXE36_001159"
     CDS             8893..10701
                     /gene="glmS"
                     /locus_tag="VXE36_001159"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0779472.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQVFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(10838..10915)
                     /locus_tag="VXE36_001160"
                     /pseudo
     CDS             complement(10838..10915)
                     /locus_tag="VXE36_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            10972..12021
                     /locus_tag="VXE36_001161"
     CDS             10972..12021
                     /locus_tag="VXE36_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0779473.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVDLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSRMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIDGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(12121..15963)
                     /gene="spuA"
                     /locus_tag="VXE36_001162"
     CDS             complement(12121..15963)
                     /gene="spuA"
                     /locus_tag="VXE36_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0779474.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLNDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGSDLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDINTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYRTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            16380..16793
                     /gene="rpsL"
                     /locus_tag="VXE36_001163"
     CDS             16380..16793
                     /gene="rpsL"
                     /locus_tag="VXE36_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0779475.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16813..17283
                     /gene="rpsG"
                     /locus_tag="VXE36_001164"
     CDS             16813..17283
                     /gene="rpsG"
                     /locus_tag="VXE36_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0779476.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17708..19789
                     /gene="fusA"
                     /locus_tag="VXE36_001165"
     CDS             17708..19789
                     /gene="fusA"
                     /locus_tag="VXE36_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0779477.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19893..24284
                     /locus_tag="VXE36_001166"
     CDS             19893..24284
                     /locus_tag="VXE36_001166"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0779478.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEAIYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNAFAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24386..24649
                     /locus_tag="VXE36_001167"
     CDS             24386..24649
                     /locus_tag="VXE36_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0779479.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24642..24920
                     /locus_tag="VXE36_001168"
     CDS             24642..24920
                     /locus_tag="VXE36_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0779480.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24941..25093
                     /locus_tag="VXE36_001169"
     CDS             24941..25093
                     /locus_tag="VXE36_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779481.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            25115..26356
                     /locus_tag="VXE36_001170"
     CDS             25115..26356
                     /locus_tag="VXE36_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0779482.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEEDPVKAWENHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAINAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIIDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVGGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            26366..26596
                     /locus_tag="VXE36_001171"
     CDS             26366..26596
                     /locus_tag="VXE36_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0779483.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            26864..27586
                     /locus_tag="VXE36_001172"
     CDS             26864..27586
                     /locus_tag="VXE36_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0779484.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27803..29137
                     /gene="pepC"
                     /locus_tag="VXE36_001173"
     CDS             27803..29137
                     /gene="pepC"
                     /locus_tag="VXE36_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0779485.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
BASE COUNT         8250 a         5550 c         6880 g         8472 t
ORIGIN      
        1 acccaatcag gtggagtttt ttagctctat ttcaggcttt tggggactat tctaaaaata
       61 atttttcgat atttttcggt atttttcgga ttttggtcgg ggaattggcg gggacttttt
      121 tagcgaatat aactaagaaa taggtctgtg gtcgcttcag ctagttcaaa ctcaatttga
      181 ttgtaagtga ctgttaattg aagaactgga actactgtaa taatgatttt gcttgtctag
      241 tagtggcgta ttaaatgaga agtgacatgt aagattgtct cttcgtttac gaaatcaaaa
      301 tttctatgaa attgatagaa tccctaacgt tctcttaatc ttaaccgtct tgtcgtacag
      361 cggttgaaga aaatgtaaac ctttgacaaa attcgtgaac tatgggataa taaaaaggaa
      421 ttgagtacta gttctatatc ataggctaga aaagacccca agctcacgac caaataagct
      481 tgaggtcttt tttgacacta tttgtccttg tttagccatt tatcgactat acgaagaacg
      541 acaccgacca caattggtcc gatgatagtt ttgagtacta attccatcat gggctatctc
      601 acctcctttc gtaggcggtg tagcagtgtc gtagaatatt ataccacata agtgctaaac
      661 ttaggagtca cccaatcagg tggctttttt gtttgtggct tggttttttg atataataga
      721 gccatgagta gaattttaga taatgagata atgggggatg aggagttagt agaacgcacg
      781 ctccgtcctc agtatttacg tgaatatatc ggacaggata aggtcaagga ccagctacaa
      841 atctttattg aagctgccaa aatgcgggat gaagcgctgg atcatgtgct cttatttggg
      901 cctccaggtc tcgggaaaac gaccatggcc tttgttattg ccaacgaact gggagtcaat
      961 cttaagcaga cgtcgggtcc agtcattgaa aaagccggag atctggtagc tattttgaat
     1021 gagttagagc ctggggatgt actttttatt gatgagatcc atcgtttgcc aatgtcagtg
     1081 gaagaggtgc tttatagtgc tatggaggac ttctacatcg atattatgat tggggctggt
     1141 gagggtagtc gtagtgttca tttggagtta ccacctttta ccttgattgg tgcgacgact
     1201 cgggctggta tgctctccaa tccgctacgg gcacgttttg ggattacagg ccatatggag
     1261 tattatgccc atgctgactt gacagaaatt gtcgagcgga cggcagatat ttttgagatg
     1321 gaaatcactc atgaggcagc atctgagttg gccctacgta gtcgtgggac ccctcgtatt
     1381 gccaatcgtc tcctcaagcg cgtgcgcgat tttgcccaga taatggggaa tggggtaatt
     1441 gatgatatta ttaccgataa ggctttgact atgctggatg ttgaccatga aggtttggac
     1501 tatgtggatc aaaaaatcct tcgtaccatg attgagatgt acagtggagg acctgttggt
     1561 ctaggaactc tttctgtgaa tatcgccgaa gagcgtgaga cagttgaaga catgtatgag
     1621 ccttacttga ttcaaaaagg ttttatcatg cggacacggt ctggacgggt ggcgactgct
     1681 aaggcatatg agcacttagg ttatgaatac agtgaaaaat aagcaagaaa tcttagaggc
     1741 ttttagagaa aatccagata tgatggccat tctgacgatc atccgagacc ttggtctgaa
     1801 agactcgtgg ttggcagcag gttctgtcag aaatttcatt tggaatcttt tgtcagacaa
     1861 atcccctttt gatcatgaaa cagatataga tgtgattttc tttgatccag atttttctta
     1921 tgaggaaacc ttattactga agaaaaagct gagagaggat tttcctcagt accagtggga
     1981 attgaaaaat caggtctata tgcatcagca cagtcctcac actgcttcct ataccagttc
     2041 tcgtgatgct atgagtaagt atccagaacg gtgtacggca gttggactgc gcttgaatga
     2101 agaatcagat tttgaactct atgtacctta tggtttggag gatattttga attttcaagt
     2161 tcgtccaact cctcatttct tagaaaatga agaccgaatg gaactctatc aaacacgttt
     2221 atccaagaaa aattggcagg agaaatggaa aaatttgatt tttaaaaata cttaaggaaa
     2281 ctttaagcta gggagtgtac actaagttca taagttaaga agaccttaac ttaaactcct
     2341 aaaacttttt cataataatc tccctataaa aataaagtcg cccaatcagg cggcttattt
     2401 ttttgaaaaa tgggcttggt gcctgagaat aaatagctta gtgatagaag aaaatgggga
     2461 aatatggtat aatgaaacga tagatttttg aataggaata agatcatgtt tggatttttt
     2521 aagaaagata aggctgtgga agtagaggtt ccgacacagg ttcctgctca tatcggcatc
     2581 atcatggatg gcaatggccg ttgggctaaa aaacgtatgc aaccgcgagt ttttggacat
     2641 aaggcgggca tggaagcatt gcaaaccgtg accaaggcag ccaacaaact gggcgtcaag
     2701 gttattacgg tctatgcttt ttctacggaa aactggaccc gtccagatca ggaagtcaag
     2761 tttatcatga acttgccagt agagttttat gataattatg tcccggaact acatgcgaat
     2821 aatgttaaga ttcaaatgat tggggagaca gaccgcctgc ctaagcaaac ctttgaagct
     2881 ttaaccaagg ctgaggaatt gactaagaac aacacaggat tgattcttaa ttttgctctt
     2941 aactatggtg gacgtgctga gattacacag gcgcttaagt tgatttccca ggatgtttta
     3001 gatgccaaaa tcaacccagg tgacatcaca gaggaattga ttggtaacta tctctttact
     3061 cagcatttgc ctaaggactt acgagaccca gacttgatta tccgtactag tggagaatta
     3121 cgtttgagca atttccttcc atggcaggga gcctatagtg agctttattt tacggacacc
     3181 ttatggcctg attttgacga agcggccttg caggaagcta ttcttgccta taatcgtcgt
     3241 catcgccgat ttggaggagt ttaggaggaa atatgaccca ggatttacag aaaagaacct
     3301 tgtttgcagg gattgccctg gctattttcc taccaatttt aatgattggg ggcctcttgc
     3361 ttcagatagc aatcggaatc atagccatgc tagccatgca tgaacttttg aagatgagag
     3421 gtctagagac catgacgatg gagggcctct tgaccctctt tgcaaccttt gcattgacca
     3481 ttcccttgga gaattacctg acttttttgc cagttgatgg gaatgtggtt gcctatagtg
     3541 ttttgatttc aatcatgtta ggaacgaccg tttttagcaa gtcttatacg attgaggatg
     3601 cggttttccc tcttgctatg agcttctacg tgggctttgg atttaatgct ttactagatg
     3661 ctcgtgttgc aggtttggac aaggctctct tagccttgtg tatcgtctgg gcgacagaca
     3721 gtggtgccta tcttgttggg atgaactatg ggaaacgaaa gttagcacca agggtatcgc
     3781 ctaataaaac ccttgagggt gccttgggtg gtattttagg agcaatttta gtaaccatta
     3841 tctttatgat agttgacagt acagttgctc ttccatatgg aatttacaag atgtcagtct
     3901 ttgctatttt ctttagcatt gctggacaat ttggtgattt actagaaagt tcgatcaaac
     3961 gtcattttgg tgttaaggat tctgggaaat ttatccctgg acatggtggt gttttggatc
     4021 gtttcgatag tatgttgctt gtatttccaa tcatgcactt atttggactc ttttaatcaa
     4081 aagacggagg aaacactatg cttggaattt taacctttat tctggttttt gggattattg
     4141 tagtggtgca cgagttcggg cacttctact ttgccaagaa atcagggatt ttagtacgtg
     4201 aatttgccat cggtatggga cctaaaatct ttgctcacat tggcaaggat ggaacggcct
     4261 ataccattcg aatcttgcct ctgggtggct atgtccgcat ggccggttgg ggtgatgata
     4321 caactgaaat caagacagga acgcctgtta gtttgacact tgctgatgat ggtaaggtta
     4381 aacgcatcaa tctctcaggt aaaaaattgg atcaaacagc cctccctatg caggtgaccc
     4441 agtttgattt tgaagacaag ctctttatca aaggattggt tctggaagaa gaaaaaacat
     4501 ttgcagtgga tcacgatgca acggttgtgg aagcagatgg tactgaggtt cggattgcac
     4561 ctttagatgt tcaatatcaa aatgcgacta tctggggcaa actgattacc aattttgcag
     4621 gccctatgaa caattttatc ttaggtgtcg ttgttttttg ggttttaatc tttatgcagg
     4681 gtggtgtcag agatgttgat accaatcagt tccatatcat gccccaaggt gccttggcca
     4741 aggtaggagt accagaaacg tcacaaatta ctaagattgg ctcacatgag gttagcaact
     4801 gggaaagctt gatccaagct gtggaaacag aaaccaaaga taagacggca ccgactttgg
     4861 atgtgactat ttctgaaaag gggagtgaca aacaagtcac tgttacaccc gaagatagtc
     4921 aaggacgtta ccttctaggt gttcaaccgg gggttaagtc agattttcta tccatgtttg
     4981 taggtggttt tacaactgct gctgactcag ctctccgaat tctctcagct ctgaaaaatc
     5041 tgattttcca accggatttg aacaagttgg gtggacctgt tgctatcttt aaggcaagta
     5101 gtgatgctgc taaaaatgga attgagaata tcttgtactt cttggcaatg atttccatca
     5161 atattgggat ttttaatctt attccgattc cagccttgga tggtggtaag attgtgctca
     5221 atatcctaga agccatccgc cgcaaaccat tgaaacaaga aattgaaacc tatgtcacct
     5281 tggccggagt ggtcatcatg gttgtcttga tgattgctgt gacttggaat gacattatgc
     5341 gactcttttt tagataatcg aggaatatta tgaaacaaag taaaatgcct atcccaacgc
     5401 ttcgcgaaat gccaagcgat gctcaagtta tcagccatgc tcttatgttg cgtgctggtt
     5461 atgttcgcca agtttcagca ggtgtttatt cttatctacc acttgccaac cgtgtgattg
     5521 aaaaagctaa aaacatcatg cgccaagaat tcgaaaagat tggtgctgtt gagatgttgg
     5581 ctcctgccct tcttagtgca gaattgtggc gtgaatcagg tcgttacgaa acctatggtg
     5641 aagaccttta caaactaaaa aaccgtgaaa aatcagactt tatcttaggt ccaactcacg
     5701 aagaaacctt tacagctatt gtccgtgatt ctgttaaatc ttacaagcaa ttgccactca
     5761 acctttatca aattcagccc aagtatcgtg atgaaaaacg cccacgtaat ggacttcttc
     5821 gtacacgtga gtttatcatg aaggatgctt atagtttcca cgctaactat gatagtttgg
     5881 atagtgttta tgatgagtac aaagcagcct atgagcgtat tttcactcgt agtggtttag
     5941 acttcaaggc tattattggt gacggtggag ccatgggtgg taaggatagc caagaattta
     6001 tggccattac atctgctcgt acagaccttg accgctgggt tgtcttggac aagtcagttg
     6061 cctcatttga cgaaattcct gcagaagtgc aagaagaaat caaggcagaa ttgctcaaat
     6121 ggatagtctc tggtgaagat accattgctt actcaagtga gtctagctat gcagctaact
     6181 tagaaatggc aacaaacgag tacaaaccaa gcaaccgtgt tgtcgctgaa gaagaagtta
     6241 ctcgtgttgc aacgccagat gttaaatcaa ttgatgaagt tgcagccttc ctcaatgttc
     6301 cagaagaaca aacgattaaa accctcttct acattgcaga tggcgagctt gttgcagccc
     6361 ttctagttgg aaatgaccaa ctcaacgaag tcaagttgaa aaatcacttg ggagcagatt
     6421 tctttgacgt tgctagcgaa gaagaagtgg cgaatgttgt tcaagcagga tttggttcac
     6481 ttggaccagt tggtttgcca gagaatatta aaattattgc agatcgtaag gtgcaagatg
     6541 ttcgcaatgc agttgtcggt gctaacgaag atggctacca cttgactggt gtgaacccag
     6601 gccgtgattt tactgcagaa tatgtggata tccgtgaagt tcgtgagggt gaaatttccc
     6661 cagatggaca aggtgtcctt aactttgcgc gtggtattga gatcggtcat attttcaaac
     6721 tcggaactcg ctattcagca agcatgggag cagatgtctt ggatgaaaat ggtcgtgctg
     6781 tgccaatcat catgggatgt tacggtatcg gtgtcagccg tcttctttca gcagtgatgg
     6841 agcaacacgc tcgcctcttt gttaacaaaa cgccaaaagg tgaataccgt tacgcttggg
     6901 gaatcaattt ccctaaagaa ttggcaccat ttgatgtgca tttgattact gtcaatgtca
     6961 aggatgaaga agcgcaagcc ttgacagaaa aacttgaagc aagcttgatg ggagctggtt
     7021 atgaagtctt gacagatgac cgtaacgaac gtgtcggtgt taaatttagc gatagtgact
     7081 tgattggtct tccaatccgt atcactgttg gtaaaaaagc ggccgatggc attgtagaag
     7141 ttaagatcaa ggcaactggt gacaccattg aggttcatgc agataacgtg cttgaaacgc
     7201 ttgaaatcct aagcaagaaa taaaaactat aatcagaaga aaaacaagga aaaaatgtaa
     7261 ctagttttta ccttgttttt tctgtataat gggagaaatg agtagataaa gaggtaaatg
     7321 tatgctaaga tttccaaagg attttgtctg gggatcctct acttctggac cgcagacaga
     7381 aggacgtgta gctggtgacg gtaagggaga caatctctgg gattactggt tccaagtgga
     7441 gccaaatcgt tactataatg ggattggttc agataagaca tcgacttttt atgaaaattg
     7501 ggagcgggat attgagcttt tgttagagac tggtcacaca gcctttcgga cttctattca
     7561 gtggtcacgg atttttccac aaggctgtgg aaaagtcaac actcaaggtg tggattttta
     7621 tcgtaaggtc tttgaggcta ttaaggctaa aggaattcgt ctgttagtca atctctatca
     7681 ttttgattta ccttttgccc ttcaagagga tggtgatggt tgggaaaata aggcgacagt
     7741 ctcagcctat gaagactatg ctcgtttttg ttttgagact tatggagatt tagtggatca
     7801 atggattacc tttaacgagc ccatcgttcc tgtagaattt ggttattttt atgatgccca
     7861 ttatccacat aaggtggatg cagaggcagc tgttaaggta gcctatcata cacaattggc
     7921 cagcagccgg gctgttaagg cttgccatga acttttgcct gattccaaga ttgggattgt
     7981 cctcaacttg acaccggctt atccacgtag ccagcatcct gctgatgtca aggcagctcg
     8041 tattgcggcc ctttttcagg cccaatcttt cttagatcca tctgtcttgg ggacttatcc
     8101 acaggagttg gtagaaatct tgcatgaaca cggtctttta cctgatgcta cagaggaaga
     8161 gttggaactc attcgtgata atacggtgga cttccttggt gtgaactact atcaaccttt
     8221 gcgtgttatg gctcctcgat ttgctaagca tccagagagt ccactcttac cagaacattt
     8281 ttacgagcct tatgtgatgc ctggacgtaa aatcaattct caccgtggtt gggagattta
     8341 tgagcaaggg atttatgaca tcgcccaaaa tatcaaggaa aattatggca atattgaatg
     8401 gatgttgact gagaatggta tgggtgttga aggggaagaa aaattccgtc aagatggaat
     8461 gattcaagat gattaccgta ttgactttgt aaaaggtcat cttcgtgaac ttcaccgtgc
     8521 cattgaagat ggtgccaact gtaagggcta cttgatttgg acctttattg actgctggtc
     8581 atggctcaac agctataaaa atcgctatgg tttggtcgaa ttagacttgg aaacgcaaga
     8641 acgtcgtctg aagaaatcag gccactggtt caaaaaatta agcgataata atggatttta
     8701 aaaaggactc tgactgatta tcccaatcgg tcagagtttt ttgcttacag gagcttaatt
     8761 tgaactatac caatttttac tcttgacaag tgaaagaaac aagtatatac tgtttttgct
     8821 gattctataa aagatgaatt agactatacc aattttaagg agaaagcaca gcttgcctgt
     8881 gtcgtatata ctatgtgtgg aattgttggt gttgttggaa acacaaatgc aactgatatt
     8941 ttgattcaag ggcttgaaaa gcttgaatac cgtggctatg attctgcggg aatttttgtc
     9001 ctagatggtg ctgataacca tttggtgaag gctgttggtc gtattgcaga attgtctgcc
     9061 aagacagctg gtgttgaggg aacaactggt atcggacata ctcgttgggc tactcacgga
     9121 aaaccaactg aggacaatgc tcacccacac cgctctgaga cagaacgttt tgtcttggtg
     9181 cataatgggg tgattgagaa ctaccttgaa atcaaggaag aataccttgc aggtcaccac
     9241 ttcaaggggc agacagatac tgaaatagcc gttcatttga ttggaaaatt tgcggaagaa
     9301 gaagggctct cagttcttga agccttcaaa aaagcccttc acatcatccg tggttcttat
     9361 gcctttgcct tggttgactc acaagatcct gaagtcatct acgtagctaa aaataaatca
     9421 ccacttttga ttggtcttgg agaaggctat aacatggtct gctcagacgc catggctatg
     9481 attcgtgaaa ctaaccaata catggaaatc catgaccaag agttggtaat cgtcaaggct
     9541 gatagtgtgg aagttcaaga ctatgatgga aatcgtcgtg agcgtgctag ctacactgct
     9601 gaacttgact tgtcagatat cggtaaggga acttaccctt actacatgct caaggaaatt
     9661 gacgagcaac caactgttat gcggaaactc atccaagcct acacagatga ggctggtcaa
     9721 gttgtcgtag acccagatat cattaaggct gttcaagacg cagaccgcat ctacatcctt
     9781 gcagctggaa catcttacca tgcaggattt gcttctaaga aaatgttgga agaattgaca
     9841 gatacaccag ttgaacttgg aatctcatct gagtggggct acggtatgcc acttctcagc
     9901 aagaaaccac tcttcatctt tatcagccaa tctggtgaaa cagcggatag tcgtcaagtt
     9961 ttggtcaagg ctaatgaaat gggaattcca agcttaacag tgacaaatgt tccaggttca
    10021 accctctcac gtgaagccaa ctataccatg ctccttcatg caggtcctga aattgctgtg
    10081 gcatcaacta aagcctatac agcgcaaatc gcagcccttg ccttccttgc aaaagcagtc
    10141 ggagaagcaa atggtaatgc taaagcgcaa gtctttgatc tggttcatga attgtcaatc
    10201 gtagctcagt ctatcgaatc aactctttca gagaaagaaa ccattgaagt caaggttcgt
    10261 gaacttcttg aaacaactcg taacgccttt tacatcggac gtggtcaaga ttactacgta
    10321 gccatggaag caagtctcaa actcaaagag atttcttata tccagtgtga aggctttgct
    10381 gcaggagaac tcaagcacgg aaccattgcc ttgattgaag aaggaacgcc tgttttggct
    10441 ctcttgtcag atccagttct tgccaaccat actcgtggaa atatccaaga ggtcgcagcc
    10501 cgtggtgcca aagtcctcac tatcgcagaa gagaatgtag ccaaagatac cgacgatatc
    10561 gtccttacga ccgtacatcc atacctctca ccaatttcaa tggtcgtacc aacgcaatta
    10621 gtcgcttact ttgcaaccct ccatcgtggc ctcgatgtgg acaaaccacg taaccttgcc
    10681 aagtcagtaa cggtagaata agctaaaaaa gtctagttat ctaggctttt tcttgtgagc
    10741 aaattggttg cttgtactca agattcgtgt tatactcttc gaaaatctct tcaaaccacg
    10801 tcaacgtcgc cttgccgtag gtatggttac tgacttcgtt agttctatcc acaacctcaa
    10861 aacactgttt tgagcagcct gcagctagct tcctagtttg ctctttgatt ttcattgagt
    10921 attagaataa tttttcaaat tgaaggacag agatagacaa ggagaatcac aatggtagaa
    10981 ttgggaattt caacatttgg ggaaataacg gagcttgaag ggactggaca aacttacagt
    11041 catgctgaac gcattcgcca gttggtggca gagattgagc tggctgacaa ggttgatttg
    11101 gatgtatatg ggattggtga gcaccatcgg gcggattttg cagtatcagc tccagagatt
    11161 gttctggccg ctggggcagt caataccaag aaaatccgtt tgaccagtgc agtcagcatt
    11221 ctgtcaagaa tggacccgat tcgtttgttc caacagtatg ccactatcga tgctttgtca
    11281 aatggacgag cggagattat ggctggaagg ggctctttca cggaatcttt ccctctgttt
    11341 ggttatgact tgaaagacta cgactctctt tttgatgaga aattagactt gcttcagtta
    11401 gtcaatgaaa agaccaagtt agactggcaa ggtcgattga ctcaaacgat tgctggtaaa
    11461 gaagtttatc ctcgtccagt tcaggacaaa ttgcccttgt ggatagctac aggtggtcat
    11521 gtcgaatcaa cagtgaagat tgctcaggct ggtctaccga ttgtatatgc tattattgat
    11581 ggtaatccac gttattttaa aaagttgatt caggcttatc gtgagattgg aagcgaagcg
    11641 ggccatgctg acaaagactt gaaagtggga gcccattctt gggggtggat tgcggaagat
    11701 ggtgagcagg cggtgaaaga ttatttccat ccgactaagc aagtggtgga tgctatttcc
    11761 aaagaccgtc cgcactggca ggaattgcgt tatgagcaat atttggagca ggtagggtca
    11821 aatggcgcca tgtttgttgg caatccagat caggtggccg aaaaattgat tcgcatgata
    11881 gaggatttag gattggaccg cttcatgctt catctaccgc ttggttctat gcctcatgac
    11941 caggttctga gagctattga actcttcgga acacaagttg cacccaaagt acgagcttat
    12001 tttgctatga aagaggctta ataaaaaatc ctaatcaagt ttattaggac aacaaatatt
    12061 gtacgaaaat taatcccccg agctataatg cttgggggat ttttctatag gagggctagc
    12121 ttagttctct tttttatttt ttagtaagaa accgagacca aggagcgcaa ggaggctgat
    12181 tcctgcaaat aggagtttgt tttcgttttt gattcctgta tttggaagtt cagcttgtct
    12241 atctggggtt gcagatatat tttccttgct agagttttct accgattctt ttcgaaccgc
    12301 ttcttttaca gatgatgctt gtgcttcttg tgctggttgt tcagcttgtg aatcagctgt
    12361 agcttggcta ggtttatttt ccgcatcagc tactttggca tctggtttag tagaatcagg
    12421 tctagcttct ggagctgggt cttgatgtgc agggtgagaa gcttcatttt gatgttcagg
    12481 cttggaaggg gttgagtctg gtttctcttc tgcagttgac tcatggctag ttccattttg
    12541 agagactcga agaacagtag ctgtaagggc attcaatttc aagccttttt cagtccattc
    12601 aagtcctttc gggttggcaa ttccgactga tcctgcttgg ttttcatctg ccaaaacttc
    12661 cgcatttctt agatgtgcaa aggcagttcc caaattaaat tcgcgagctt tttcatccgc
    12721 attgacaaag actgcgtaga tatcgccgtt tggagcagtg atttgatagc caatcactac
    12781 atcctctttt tccacaccat tttggcctgg gacagtgatg aggtggacac ggtctttgat
    12841 atcttgaaga ctcttaagtc ggaaggcatc tgtagattga cgaagggcaa tcaaaccttt
    12901 catatagtca cggctcttga cattttcagg ataagcttta ccatctgtag ccttagtcca
    12961 gtcaaacttg ttgactgcat cactagaatc gtaagagtca tggatgaagt aaggatagtc
    13021 aaatgggttg ccgtccttat cacgcaacaa gtgagatttg tttggaacct tatcctctgc
    13081 tacaggagtt ctgtaggctg ggtcacggaa ttgtttggta cgtccatatt cctggccaga
    13141 gtggataaac ggagttcctt gagctgtcaa gaccatgaga tttccaagtc gtaaacgacg
    13201 gtggatttca gcatagttct cagctttgct tgggtctttt ttgatagact gggcaatgat
    13261 gtcaaagagg gtcaagttat catgggctgc gatgtattgg atgacatctc caggactgtc
    13321 tgcttcaaag ttggttggtt gagcaatgag gtttttgaag atagtgttga tatcacgctt
    13381 gccacctgtg ataaaggcag gttgaccttc gtttggataa ccagacttga ggttgttacg
    13441 gatgtcatct gagaagacag caacagtatc ggtatgtttc atccaatctt ggtcagcagc
    13501 cttagtaggc atattttcat caccagcata ggttctccaa ccttcaccca gcatgatgag
    13561 gtttggattg agggcgcgtg cagccttgta agcttcttcg atagaagccg catcatggtc
    13621 tcccatcata tcgaagcgga agccatccac tttgtaggta tcaactagat atttgataga
    13681 gtcaactagg agccgtttgg tcatatggtg ggttgtcccc aaacgtccac caccaaagct
    13741 agttcgaggt gtgccatcgg catccataaa gtggtagtag tttggttcca aatcttcaaa
    13801 gagatcgact ttggctgtgt ggttataaac gacatctagg atagctccca taccacgttt
    13861 gtggatttcg ttgatgaggt ttttaaattc tgcgattcgt ttttctggat tcttaggatc
    13921 gcttgagtac ataccagtca aggagaagta gttttgaggg tcatatcccc agttgtagtt
    13981 gctgttgctt gaagcgtagt cagacaatcg ttcatggttt ttcaattcat tgacaaagta
    14041 gtaagacaag actggaagga gctggatatg ggttacaccc aagtctttga gatagtctag
    14101 tttttcaatg aaggcttcaa aagtcccaaa tggtttggtc aagtcttttg caatggcagg
    14161 atctgaagtg aagtcacgca catgagcttc gtagataacg gcgtcttcac gagtcttgaa
    14221 attgtgaatc ttaccataag tcaagtcttg aggtccgagt ttagctggat ctacaaaggc
    14281 ggctttagcc actttatggg catcgtcaat cttggcatcg tcgctattcc aagcagcaag
    14341 agatttagcg taaggatcga gtgcaagaac agttttacct tgacgctcga tttggtattg
    14401 ataatagtag ccagtgaaat ctgtgattcc gagtttgttt gtgctgtcta gagtttgttt
    14461 ccaagttcct ctttcccctt tttcgagagc gacagttcca actactttgt cagggtcatt
    14521 cttgtcgtag acaacaacag aaaccttatc agcacttggt gaccaaaggg tcaaatcaac
    14581 ttgttttcct tcttctttta ggtcagatcc cagtttgcca tcatagctgt atgtctcatc
    14641 tttcaggcgc cagcttgttt tggtagtgaa ttggtcggaa ttgtagctaa cagtataagg
    14701 atgttttgtg tcagagaaat ctccgctgta ggtcactttc ttaccagctt catcgattgc
    14761 aacatcggta atagttacct tgtttcctag gtgattagtg atgttggagt gtttgaggat
    14821 atcttctttt ttagcaccga caagtgttga aaagctactt tcaatgctag aagtgcctac
    14881 gtgttgggct cctgtcatac ggatatcatg gacatagtat ggatttgtgt aaatcgattc
    14941 atcatcgtct tttaggaaaa tttggctatg atttttcaaa tctgtgaact tataattttc
    15001 tttacggatt ttcacgtcgt ctccttgttt gctctcatct agtaataaaa atccaaattc
    15061 tcttgcggct tcattaagag gaatgtcgat atagcggcca tatttgcctg tagccgtaaa
    15121 gtctgttccg tcaggccatt gagcgctact tggatttttc acatctcccc agtaccagag
    15181 agatttcttg tcatagttgc catctgtgcg gtagtagttg acgcgaacag ttcctgcagg
    15241 ctgtggctcg taagagaaaa ccttgtaatc ttggtctaac caagcctcgt tcatttttgg
    15301 aactagtttt tctacagatt tatcgccggt tagatttttt ccagctgtat tgttgatgag
    15361 gaagctaatt ttcttggctt gttctccctt taatttgaca tctaggtaat agccgtagtc
    15421 atctttcttg gcatccttga aggacaaagc tccgtttggc cagttttcag atggtttttc
    15481 aacatcgtcc caagtccata gtccttgagc atccttgttt tcttcaggaa gttttttgac
    15541 atggatacgg aagtagttat cttcgatggg ctcttctgcc ttagtttcag ttgttactgg
    15601 actagtagaa gtagttggct cacttgaacg atcttgtcca gtttgtggtg ctggatcggc
    15661 tgggcttgca gcaggttttt cttctgtttt ctctagggaa gcgtttgcat ttccaggtga
    15721 agaaatatca ctttcgttct taccagagcc agctgctgta tcattaagag gttgggcaag
    15781 ggtggttgta tttctgttgt tgggttcgtt agtggttggt gtactttcgt cggatgagat
    15841 agttggtgta gccatggcaa gcaagacaag gcttgcgccg ataaggacag aaccagttcc
    15901 atttttgagg gaacggatgc tgtagaccat ttttttctca gtgtgagagg gtgtttttct
    15961 cataatgatt ctccaatcaa taaatttcta tatcagtata gcatgtagta aaacaatatg
    16021 caagcgtttt ctttgatttg tgaaaaaaat tcttactttt gagaagtttt ctgtactatt
    16081 ttatatatca gtataaatga cggagataaa aatgtcacat aagccaagcc gtattattag
    16141 gaagatgatg tgttcccagc tatttttatt cagaaattga tctctaacat taccaataaa
    16201 aaagaaaaat atcttgacaa gcaagggaaa attttgttac aataataaac ggtacttttt
    16261 acttttggtc tctcaagagt gtacagggac gtgctgacaa atgttgcaaa agtacacaca
    16321 gatgatatct gtcaccaagt gtatcatcac caaaaataaa aaaacacagg agaatgtaga
    16381 tgcctacaat taaccaattg gttcgcaaac cgcgtaaatc aaaagtagaa aaatctaaat
    16441 caccagcttt gaacgttggt tacaatagtc ataaaaaagt tcaaacaaac gtttcttcac
    16501 cacaaaaacg tggtgttgca actcgtgttg gaacaatgac acctaaaaaa cctaactcag
    16561 cccttcgtaa attcgctcgt gtacgtttga gcaaccttat cgaagttact gcctacatcc
    16621 caggtatcgg acacaacttg caagagcaca gcgtggtgct tcttcgcggt ggacgtgtaa
    16681 aagaccttcc aggggtacgt taccatatcg tccgtggtgc acttgatact gcaggtgtta
    16741 acgatcgtaa acaaggccgt tctaaatacg gtactaaacg tccaaaagca taaggaaagg
    16801 ggataaagag aaatgagtcg taaaaataga gctccaaaac gtgacgtatt gccagatccg
    16861 ctatacaatt cacaactagt tactcgtctt atcaaccgcg ttatgcttga tggtaaacgt
    16921 ggtactgctg cttcaatcgt ttacggtgct tttgagcaaa tcaaagaagc tactggcaac
    16981 gatgcacttg aagtatttga aacagctatg gaaaacatca tgcctgtact tgaagtacgt
    17041 gcacgtcgtg ttggtggttc taactaccaa gtcccagttg aagttcgtcc agaacgtcgt
    17101 acaacacttg gacttcgttg gttggtaaca atcgctcgtc ttcgtggtga acacacaatg
    17161 caagaccgtc ttgcaaaaga aatcttggat gctgctaaca acactggtgc agcagttaag
    17221 aaacgtgaag atactcaccg tatggctgaa gctaaccgtg cattcgcaca cttccgttgg
    17281 taagatagga tgcgaaagcg ttaagaaagt cccagagaaa atagggaatc gaagcaggtt
    17341 gcggttgcaa ccaatgagat tcatcttttt ctccagactt ttagcttgag ctcaactaaa
    17401 tcatgatgct aggaacggta aggatgcaag gtgaaaatag gaaactgacg cagtattcga
    17461 cgaatataag gagttttatc tttttcacgc agcatcccgt tccagctcac atcggctaac
    17521 taactttagc ccgggttcaa attagctaaa tcgattagta ttagctataa ctcagcttac
    17581 catctcgtaa gttgaaacca acaatagcat gaaaacattg agaacgggta ggtcctgcct
    17641 atccgttttt attaaaatcg tgttataata gaatagaaat caaaaataaa taggagaaac
    17701 aaacctcatg gcacgcgaat tttcacttga aaaaactcgt aatatcggta tcatggctca
    17761 cgtcgatgcc ggtaaaacaa caactactga gcgtattctt tactacactg gtaaaatcca
    17821 caaaatcggt gaaactcacg aaggtgcgtc acaaatggac tggatggagc aagagcaaga
    17881 acgtggtatc acgatcacat ctgctgcgac aacagctcaa tggaacaacc accgcgtaaa
    17941 catcatcgac acaccaggac acgtggactt cacaatcgaa gtacaacgtt ctcttcgtgt
    18001 attggatggt gcggttaccg ttcttgactc acaatcaggt gttgagcctc aaactgaaac
    18061 agtttggcgt caagcaactg agtacggagt tccacgtatc gtatttgcca acaaaatgga
    18121 caaaatcggt gctgacttcc tttactctgt aagcacactt cacgatcgtc ttcaagcaaa
    18181 tgcacaccca atccaattgc caatcggttc tgaagatgac ttccgtggta tcattgactt
    18241 gatcaagatg aaagctgaaa tctatactaa cgaccttggt acggatatcc ttgaagaaga
    18301 catcccagct gaataccttg accaagctca agaataccgt gaaaaattga ttgaagcagt
    18361 tgctgaaact gacgaagaat tgatgatgaa atacctcgaa ggtgaagaaa tcactaacga
    18421 agaattgaaa gctggtatcc gtaaagcgac tatcaacgtt gaattcttcc cagtattgtg
    18481 tggttcagcc ttcaaaaaca aaggtgttca attgatgctt gatgcggtta tcgactacct
    18541 tccaagccca cttgacatcc cagcaatcaa aggtattaac ccagatacag acgctgaaga
    18601 aactcgtcca gcatctgacg aagagccatt tgcagctctt gccttcaaga tcatgactga
    18661 cccattcgta ggtcgtttga cattcttccg tgtttactca ggtgttcttc aatcaggttc
    18721 atacgtattg aatacttcta aaggtaaacg tgaacgtatc ggacgtatcc ttcaaatgca
    18781 cgctaacagc cgtcaagaaa tcgacactgt ttactcaggt gatatcgctg ctgccgttgg
    18841 tttgaaagat actacaactg gtgactcatt gacagatgaa aaatctaaaa tcatccttga
    18901 gtcaatcaac gttccagaac cagttatcca attgatggtt gagccaaaat ctaaagctga
    18961 ccaagacaag atgggtatcg cccttcaaaa attggctgaa gaagatccaa cattccgcgt
    19021 tgaaacaaac gttgaaactg gtgaaacagt tatctcaggt atgggtgaac ttcaccttga
    19081 cgtccttgtt gatcgtatgc gtcgtgagtt caaagttgaa gcgaacgtag gtgcgcctca
    19141 agtatcttac cgtgaaacat tccgcgcttc tactcaagca cgtggattct tcaaacgtca
    19201 gtctggtggt aaaggtcaat tcggtgatgt gtggattgaa tttactccaa acgaagaagg
    19261 taaaggattc gaattcgaaa acgcaatcgt cggtggtgtg gttcctcgtg aatttatccc
    19321 agcggttgaa aaaggtttgg tagaatctat ggctaacggt gttcttgcag gttacccaat
    19381 ggttgacgtt aaagctaagc tttatgatgg ttcatatcac gatgtcgact catctgaaac
    19441 tgcctttaag attgcggctt cactttccct taaagaagct gctaaatcag cacaaccagc
    19501 tatccttgaa ccaatgatgc ttgtaacaat cactgttcca gaagaaaacc ttggtgatgt
    19561 tatgggtcac gtaactgctc gtcgtggacg tgtagatggt atggaagcac acggtaacag
    19621 ccaaatcgtt cgtgcttacg ttccacttgc tgaaatgttc ggttacgcaa cagttcttcg
    19681 ttctgcatct caaggacgtg gtacattcat gatggtattt gaccactacg aagatgtacc
    19741 taagtcagta caagaagaaa ttattaagaa aaataaaggt gaagactaat ccgtcctcac
    19801 tctagaagga agtcacttag tggcttcctt ttgtctttag aaaatacctc taaatatggt
    19861 aaaatagtag aagaataatg tgaggaaaat gaatgtcaaa tagttttgaa attttgatga
    19921 atcaattggg gatgcctgct gaaatgagac aggctcctgc tttagcacag gccaatattg
    19981 agcgagttgt ggttcataaa attagtaagg tatgggagtt tcatttcgta ttttctaata
    20041 ttttaccgat tgaaatcttt ttagaattaa agaaaggttt gagcgaagaa ttttctaaga
    20101 caggcaataa agctgttttt gaaattaagg ctcggtctca agaattttca aatcagctct
    20161 tgcagtccta ctatagggag gctttctctg aaggtccatg tgctagtcaa ggttttaagt
    20221 ccctttatca aaatttgcaa gttcgtgctg agggtaatca gctatttatt gaaggatctg
    20281 aagcgattga taaggaacat tttaagaaga atcatcttcc taatttagcc aaacaacttg
    20341 aaaagtttgg ttttccaact tttaactgtc aagtcgagaa gaatgatgtc ctgacccaag
    20401 agcaggaaga ggcctttcat gctgaaaatg agcagattgt tcaagctgcc aatgaggaag
    20461 cgcttcgtgc tatggaacaa ctggagcaga tggcacctcc tccagcggaa gagaaaccag
    20521 tctttgattt tcaagcgaaa aaagctgcag ctaaacccaa gctggataag gcggagatta
    20581 ctcctatgat cgaagtgacg acagaggaaa atcgtctggt atttgaaggg gttgtttttg
    20641 atgtggagca aaaagtgact agaacaggtc gtgttttaat caactttaaa atgacggact
    20701 atacttcaag tttttctatg caaaagtggg ttaaaaacga ggaagaggcc cagaagtttg
    20761 acctcatcaa gaagaattct tggctccgag ttcgagggaa tgtggagatg aataacttca
    20821 cacgcgattt gactatgaac gtacaggatc tgcaggaagt tgttcactat gagcggaagg
    20881 atttgatgcc agaaggtgag cgtcgggttg agtttcatgc tcatactaac atgtcgacta
    20941 tggatgcttt gccagaggtc gaagagattg ttgcaacagc tgctaagtgg ggacacaagg
    21001 cggttgctat cacagaccat gggaatgtcc agtcctttcc acatggctat aaggcggcta
    21061 agaaagcggg aatccagctg atctatggga tggaagccaa tatcgtggag gaccgtgtcc
    21121 ctatcgtcta taacgaagtg gagatggact tatcagaagc aatctacgtg gtctttgacg
    21181 tggaaacgac gggactttca gctatctata atgacttgat tcaggttgcg gcctctaaga
    21241 tgtacaaggg gaatgttatt gctgaatttg atgaatttat caatcctggg catcccttgt
    21301 cagcttttac tacagagtta actggaatta cagatgatca tgtcaaaaat gccaaaccac
    21361 tagaacaagt tttgcaagaa ttccaagaat tttgcaagga tacggtccta gttgcccaca
    21421 atgctacctt tgacgttggc tttatgaatg ctaattatga gcgtcatgat cttccaaaga
    21481 ttagtcagcc agttattgat acgctggagt ttgctagaaa cctctatcct gagtataaac
    21541 gccatggttt ggggcctttg accaagcgtt ttggtgtggc cttggaacat caccacatgg
    21601 ccaactacga tgcggaagcg actggtcgtc tgcttttcat ctttatcaaa gaggtagcag
    21661 aaaaacatgg tgtgaccgat ttagctagac tcaacattga tctaatcagt ccagattctt
    21721 acaaaaaagc tcggatcaag catgcgacca tctatgtcaa gaatcaggta ggtctaaaaa
    21781 atatctttaa gctggtttcc ttgtctaata ccaagtattt tgaaggagtg ccacggattc
    21841 cgagaacggt tctagatgcc catcgagagg gcttgatttt aggttcagcc tgttcagagg
    21901 gtgaagtttt tgacgtggtc gtttctcaag gtgtggatgc ggcggttgag gtggccaagt
    21961 attatgactt tatcgaggtc atgccaccgg ctatctatgc gcccttgatt gctaaagagc
    22021 aggtcaagga tatggaggaa ctccagacca ttatcaagag tttgatagag gttggagacc
    22081 gccttggcaa gcctgttctg gctacgggaa atgttcacta tatcgaaccg gaagaagaga
    22141 tttatcgtga aattatcgtc cgtagtttgg gacagggtgc gatgattaat cgaactatcg
    22201 gtcatggtga acatgcccaa ccagcaccac ttccaaaggc tcattttcga acgactaatg
    22261 agatgttgga tgaatttgcc tttttgggag aggaactggc tcgtaaactg gttattgaaa
    22321 acaccaatgc ctttgcagaa atatttgaac ccgttgaagt cgttaagggt gacttgtata
    22381 cgcctttcat cgacaaggct gaagaaacag ttgctgagtt gacctataag aaagcttttg
    22441 agatttatgg aaatccgctg ccagatattg ttgatttgcg gattgaaaaa gaattaacat
    22501 ccatactggg gaatggattt gctgtgattt atctggcatc gcagatgctg gtgcaacgtt
    22561 ctaatgaacg gggttatttg gttggttctc gtgggtctgt cggatctagt ttcgttgcga
    22621 ccatgattgg gattacggag gtcaatcctc tctctcctca ctatgtctgt ggtcagtgtc
    22681 agtacagtga gtttatcaca gatggttcgt acggttcagg atttgatatg ccccataagg
    22741 actgtccaaa ctgtggtcac aaactcagta aaaacggaca ggatattccg tttgagacct
    22801 tccttggttt tgatggggat aaggttcctg atattgactt gaacttctcg ggagaagatc
    22861 agcctagcgc ccacttggat gtgcgtgata tctttggtga agaatatgcc ttccgtgcgg
    22921 gaacagttgg tacggtagct gccaagactg cctatggatt tgtcaagggt tacgagcgag
    22981 attatggcaa gttttatcgt gatgcagaag tagaacgcct cgctcaagga gcggcgggtg
    23041 tcaagcggac aacaggccaa cacccggggg gaatcgttgt tattccgaac tacatggatg
    23101 tctacgattt tacgcctgtc cagtatccag cagatgatgt cacggctgaa tggcagacca
    23161 ctcactttaa cttccacgat atcgatgaga acgtcctcaa actcgatgta ctgggacatg
    23221 atgatccgac catgattcga aaacttcagg atttgtctgg tattgaccct aataaaattc
    23281 ctatggatga cgaaggcgtg atggcactct tttctgggac tgatgtgcta ggggtaacac
    23341 ctgaacaaat tggaacgcct acgggtatgt tggggattcc agagtttgga acaaatttcg
    23401 tacgtggaat ggtagacgaa acccatccga caacctttgc ggaattgctt cagctgtctg
    23461 gtctgtccca cggtactgat gtttggttgg ggaatgctca ggatctgatt aagcaaggaa
    23521 tagcggacct atcgactgtt atcggttgtc gggacgacat catggtttac ctcatgcatg
    23581 cgggtctgga acctaagatg gcctttacta ttatggaacg ggtacgtaag ggtttgtggc
    23641 taaagatttc agaagaggag agaaatggct atatcgaagc aatgaaggct aataaggtgc
    23701 cagagtggta tatcgaatcc tgtgggaaaa ttaagtacat gttccctaag gcccatgcgg
    23761 cagcctacgt tatgatggcc ttgcgtgtag cttacttcaa ggttcaccat cctatttatt
    23821 actactgtgc ttacttctcc attcgtgcta aggcttttga tatcaagacc atgggtgcgg
    23881 gcttggaggt catcaagcgc agaatggaag aaatctctga aaaacggaag aacaatgaag
    23941 cctctaatgt ggaaatcgat ctctatacaa ctcttgagat tgtcaatgag atgtgggaac
    24001 gaggtttcaa gtttggtaaa ttagatctct actgtagtca ggcgacagag ttcctcatcg
    24061 acggggatac ccttatccca ccatttgtag caatggatgg tctgggagag aacgttgcca
    24121 agcaactggt gcgggcgcgt gaagagggag aattcctctc taaaacagaa ctacgcaagc
    24181 gtggtggact ctcatcaacc ttggttgaaa agatggatga gatgggtatt cttggaaata
    24241 tgccagagga taaccagttg agtttgtttg atgagttgtt ttaaaaaatt gcttaataat
    24301 ctattaaaag aggctaacgt atatccaata gatttacatt agctttcttt tttgttaaaa
    24361 tagtctatgg aaagagggtg agagtatgtc aaagatgagt ataagcatcc gtctggatag
    24421 tgaggttaag gagcaggccc aacaggtgtt tagtaatctg ggaatggata tgacaacagc
    24481 tattaatatt ttccttcgtc aggcaattca atatcaggga ttaccttttg atgttagact
    24541 agacgaaaat cggaagttgc tccaagtgtt aacggattta gaccaaaatc gtaatatgag
    24601 ccagtctttt gaatcagtct cagatttgat ggaggactta cgtgcttaag attcgttatc
    24661 ataaacagtt taaaaaagat tttaagttgg ctatgaagcg tggtttgaag gcagaattat
    24721 tagaagaagt tttgaatttt ctggttcaag aaaaagaaca tcctgccaga tatcgtgatc
    24781 attcattgac ggcatccaag cattttcaag gagttcgtga atgccatacc cagccagatt
    24841 ggcttttggt ttataaagta gacaagtcgg aattgatttt aaatttgctg aggacaggca
    24901 gtcacagtga tttattttaa tctattttaa gggggttctc atgaaactaa gaatatttgc
    24961 ggaagataag ccggctaaga aggtatttga atatcaatta gaacttgctg atcgtacaat
    25021 tcttctatcg acagcactct tgtcaggtgc tattgcttta gcaggaatct tttctgcttt
    25081 gaaagaaaaa taaaaataga aaagagaaaa cagaatggtt ttaccaaatt ttaaagaaaa
    25141 tctagaaaaa tatgcgaaat tgttggttgc gaacggaatt aacgtgcaac ctggtcacac
    25201 tttggctctc tctattgatg tggagcaacg tgaattggca catctaatcg tgaaagaagc
    25261 ttatgccttg ggtgcgcatg aggtcatcgt tcagtggaca gatgatgtga ttaaccgtga
    25321 gaaattcctc catgccccga tggagcgttt ggacaatgtg ccagaataca agattgctga
    25381 gatgaactat ctcttggaga acaaggctag ccgtcttgga gttcgttcat ctgatccagg
    25441 tgccttgaac ggagtggatg ctgacaagct atcagcttct gctaaagcta tgggacttgc
    25501 catgaaacca atgcgaatcg caactcaatc caacaaggtt agctggacgg tagcagctgc
    25561 tgctggactt gagtgggcta agaaagtctt tccaaatgct gcgagcgatg aagaagcagt
    25621 cgatctcctt tgggaccaaa ttttcaaaac ttgccgtgtc tatgaagaag atcctgttaa
    25681 ggcttgggaa aatcatgcag ctatccttaa gagcaaggct gatatgctta ataaagaaca
    25741 attttcagcc cttcactaca cagcgccagg gactgatttg acccttggtt tgccgaagaa
    25801 ccacgtttgg gaatcagctg gtgctatcaa tgcacagggc gaaggtttct tgccaaatat
    25861 gccgacagaa gaagtcttca cagctccaga cttccgtcgt gcagatggtt atgtaacctc
    25921 tacaaaaccg cttagttata acggaaacat tattgaaggt attaaggtga cctttaagga
    25981 tggacaaatc atagatatta ctgctgagaa gggtgatcag gttatgaagg atcttgtctt
    26041 tgaaaatgcg ggtgcgcgtg ccttgggtga atgtgccttg gtaccagatc caagcccaat
    26101 ttctcagtca ggtattacct tctttaacac tcttttcgat gaaaatgcgt caaatcactt
    26161 ggctatcggt gcagcctatg cgactagcgt cgttggtgga gcggagatga gcgaagagga
    26221 gcttgaagct gcagggctta accgttcaga tgttcacgta gactttatga ttggttctaa
    26281 ccaaatggat atcgatggta ttcgtgagga tggaacgcgg gtacctcttt tccgtaatgg
    26341 gaattgggca aattaaggag ataatatgtt aggaagtatg ttcgttggtc tcctagtggg
    26401 atttttagca ggtgctatga ccaatcgtgg agagcgaatg ggatgttttg gaaaaatgtt
    26461 tctcggttgg atcggagcct ttctaggtca cttgctcttt ggaacttggg ggccagtttt
    26521 atcaggaaca gctattatcc cagcgatttt aggagccatg attgttttag ctattttttg
    26581 gagacgagga agttaatttc ctaaatctga tactcaatga aaatcaaaga gcaaactagg
    26641 aaactagccg caggttgctc aaagcactgc tttgaggttg cagatagaac tgacgaagtc
    26701 agctaaaaac actgttttga ggttgcagat agaactgacg aagtcagtaa catatatacg
    26761 gcaaggcgac gttgacgcgg tttgaagaga tttttgaaga gtatgaaacg aaaaggaggt
    26821 tggtcattgt actagcctcc ttttgatatg atataatagt tctatgagat tagataaatt
    26881 tttagttgcc tgtgcggtgg gaagtcggac tgaggtcaaa aacttgctca aggctgggcg
    26941 cgtgactgta aatggtaaaa aagaaaaatc agctaaattg cagattgatg aaaaaataga
    27001 tgagattcgc tttgatgggc aagtgttgga gtatgaagag tttgtctact acatgatgaa
    27061 caagcccaaa ggagttatct cagcgactga ggatcccaag cacagaaccg ttctggactt
    27121 gttggatgac ttggcgcgga gtaaggaagt ttttccagta ggacgcttgg atattgacac
    27181 gcatggtctt ttgctcttga ccaataatgg tcagctggct catgttcttc tttcgcccaa
    27241 gcgtcatgtg gacaagactt atcaggctca ggtcaaggga attatgaccc aagaagatgt
    27301 ggagacattt atcaagggca ttccgctcaa agactttacc tgtcagcccg ctagactgga
    27361 gattctttcc acagatgcag aaaagaatca gagccaaatc cgtgtgacca ttgcagaagg
    27421 gaagtttcat cagatcaagc gtatggtggg ctactgtggc aaggaagtgg tggacttgca
    27481 acgattgact atgggaactt tagtattaga tgagaacctg gaacgagggg aatggcgtcg
    27541 cttgaccaag gaagaattag aaattctccg cgctaatatt atttaattta gtttaatact
    27601 caatgaaaat caaagagcaa actaggaaac tagccgcagg ctgtacttga gtacggcaag
    27661 gcgacgttga cgtggtttga agagattttc gaagagtata aattcgaaaa aggtgaggga
    27721 gaatgtcctt accttttatg ttttttagtt gcttcctttg tgaaaagagt tataatagac
    27781 tgtagaataa aaggaggaat ctatgaacgc gattcaagaa tcatttactg ataaactatt
    27841 tgccaactat gaagcaaatg taaaatacca agcgattgaa aatgctgcca gccacaacgg
    27901 aatttttgca gctctggaac gtcgccaaag ccatgtagac aacacacctg ttttctcatt
    27961 ggatttaacc aaggacaagg tcactaacca gaaagcgtct ggtcgttgct ggatgtttgc
    28021 ggctctcaac accttccgcc acaaactcat ctcgcaatac aaattggaga actttgagtt
    28081 gtcacaagcc cacactttct tctgggataa gtatgagaaa tcaaactggt tcttggagca
    28141 agtcattgcg acttcagacc aagaattgac tagccgcaag gttagcttct tactccaaac
    28201 acctcaacaa gatggtggtc aatgggatat ggtcgtttcc ctctttgaaa aatacggtgt
    28261 cgtgcctaag tcagtttatc ctgagtctgt ttcatctagc agcagtcgtg agctaaatgc
    28321 gatccttaat aaattgcttc gtcaagatgc tcaaatcttg cgtgatttgc ttgtttctgg
    28381 tgcagatcaa gtgactgttc aagctaagaa agaagacctc ttgcaagaaa tctttaactt
    28441 tcttgctatg tcattaggac ttccaccacg caagtttgac tttgcttatc gcgataaaga
    28501 taacaactac aaaagtgaaa aaggaatcac accacaagag ttctacaaga aatatgtcaa
    28561 tcttccttta gaagactacg tttctgttat caatgctcca actgctgata aaccttacgg
    28621 aaaatcttac acagttgaga tgttggggaa tgtggttggt agccgtgcag ttcgctacat
    28681 caacgttcct atggagcgct tgaaagagtt ggcgattgct caaatgcaag caggtgagac
    28741 tgtttggttt ggttcagatg tcggtcagct cagcaaccgt aaagctggaa tccttgcgac
    28801 agatgtttat gactttgaat caagcatgga cattaaactt actcaagaca aggctggacg
    28861 tttggactat agtgaaagct tgatgaccca cgccatggtc ttgacaggtg ttgacttgga
    28921 cgaaaatggt aaatcaacca agtggaaggt tgaaaactca tggggagaca aggtcggtac
    28981 agatggttac tttgttgcct cagacgcttg gatggacgaa tacacatacc aaatcgttgt
    29041 tcgtaaggaa ttgctgacag cagaagaaca agctgcctat ggagcagaac caatcgtact
    29101 tgcaccatgg gatccaatgg gagccttggc tgaataaaag catagaaaaa ag
//
LOCUS       DAVLHB010000024        26335 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLHB010000024 DAVLHB010000000
VERSION     DAVLHB010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.024"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            293..2011
                     /locus_tag="VXE36_001174"
     CDS             293..2011
                     /locus_tag="VXE36_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0779486.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            2122..2469
                     /locus_tag="VXE36_001175"
     CDS             2122..2469
                     /locus_tag="VXE36_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0779487.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(2747..3583)
                     /locus_tag="VXE36_001176"
     CDS             complement(2747..3583)
                     /locus_tag="VXE36_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779488.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(3596..4225)
                     /locus_tag="VXE36_001177"
     CDS             complement(3596..4225)
                     /locus_tag="VXE36_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0779489.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(4235..4876)
                     /locus_tag="VXE36_001178"
     CDS             complement(4235..4876)
                     /locus_tag="VXE36_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0779490.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(5022..6251)
                     /locus_tag="VXE36_001179"
     CDS             complement(5022..6251)
                     /locus_tag="VXE36_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0779491.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(6241..7407)
                     /locus_tag="VXE36_001180"
     CDS             complement(6241..7407)
                     /locus_tag="VXE36_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0779492.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            7551..8564
                     /locus_tag="VXE36_001181"
     CDS             7551..8564
                     /locus_tag="VXE36_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0779493.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(8609..9028)
                     /locus_tag="VXE36_001182"
     CDS             complement(8609..9028)
                     /locus_tag="VXE36_001182"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0779494.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(9039..10445)
                     /gene="atpD"
                     /locus_tag="VXE36_001183"
     CDS             complement(9039..10445)
                     /gene="atpD"
                     /locus_tag="VXE36_001183"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0779495.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(10531..11409)
                     /locus_tag="VXE36_001184"
     CDS             complement(10531..11409)
                     /locus_tag="VXE36_001184"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0779496.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(11425..12930)
                     /locus_tag="VXE36_001185"
     CDS             complement(11425..12930)
                     /locus_tag="VXE36_001185"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0779497.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENAMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(12945..13481)
                     /locus_tag="VXE36_001186"
     CDS             complement(12945..13481)
                     /locus_tag="VXE36_001186"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0779498.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(13481..13975)
                     /gene="atpF"
                     /locus_tag="VXE36_001187"
     CDS             complement(13481..13975)
                     /gene="atpF"
                     /locus_tag="VXE36_001187"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0779499.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(13989..14705)
                     /gene="atpB"
                     /locus_tag="VXE36_001188"
     CDS             complement(13989..14705)
                     /gene="atpB"
                     /locus_tag="VXE36_001188"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0779500.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(14740..14940)
                     /locus_tag="VXE36_001189"
     CDS             complement(14740..14940)
                     /locus_tag="VXE36_001189"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0779501.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(15015..16022)
                     /locus_tag="VXE36_001190"
     CDS             complement(15015..16022)
                     /locus_tag="VXE36_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0779502.1"
                     /translation="MQNHYTTKGEHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKVLKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRSKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            complement(16443..16841)
                     /locus_tag="VXE36_001191"
     CDS             complement(16443..16841)
                     /locus_tag="VXE36_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779503.1"
                     /translation="MENKESHKSQKIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(17169..17651)
                     /gene="greA"
                     /locus_tag="VXE36_001192"
     CDS             complement(17169..17651)
                     /gene="greA"
                     /locus_tag="VXE36_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0779504.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(17722..19377)
                     /gene="mltG"
                     /locus_tag="VXE36_001193"
     CDS             complement(17722..19377)
                     /gene="mltG"
                     /locus_tag="VXE36_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0779505.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(19458..19952)
                     /locus_tag="VXE36_001194"
     CDS             complement(19458..19952)
                     /locus_tag="VXE36_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779506.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(19949..20413)
                     /locus_tag="VXE36_001195"
     CDS             complement(19949..20413)
                     /locus_tag="VXE36_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779507.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(20423..21757)
                     /locus_tag="VXE36_001196"
     CDS             complement(20423..21757)
                     /locus_tag="VXE36_001196"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0779508.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(21768..22385)
                     /locus_tag="VXE36_001197"
     CDS             complement(21768..22385)
                     /locus_tag="VXE36_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0779509.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(22433..25531)
                     /locus_tag="VXE36_001198"
     CDS             complement(22433..25531)
                     /locus_tag="VXE36_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0779510.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFAVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(25652..>26335)
                     /locus_tag="VXE36_001199"
     CDS             complement(25652..>26335)
                     /locus_tag="VXE36_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0779511.1"
                     /translation="EIREKILHYHKQKFSPEMMVNKKQVKVGISTIYYWFHNGHLGLT
                     KADMLYPRKRKGVKKQANPNFKPAGKSIEERPDVINLRLENGHYEIDTVLLTKIKNYC
                     LLVLTDRRSRHQIIRLIPNKTAESVNQALTLLLGEHRILSITADNGSEFKRLSEVFPE
                     EHIYYAHAYSSWERGSNENHNRLIRRWLPKGTKKTTPKEVAFIENWINNYPKKCLDYK
                     SPSEFLLGG"
BASE COUNT         7734 a         5821 c         4836 g         7944 t
ORIGIN      
        1 ctgtgcccct ctttgatgta atctaatgct cgctgtttaa aatcagtact atatgccata
       61 gctttattat aatatgcttg tttaaaacta agtaactata tcaatgtttt gttatgagaa
      121 gacttacttt ttttactgaa attgaatttt tcctagcctc aacatcatat aaccccaaaa
      181 ttcaatctga cctggtttga agagatgttc gaagcagata aggttttact aaaactaaaa
      241 aaaatgatat aatcaaactg attaaatgtt ttaaaaataa aggagaattt gaatgtctta
      301 ccaagaaaat taccagaaat gggttgattt tgtggagctt cctgactacc ttcgtcaaga
      361 tttggaaaat atggacgaaa aaactaagga agatgccttc tatacaaatc ttgaatttgg
      421 tactgcaggt atgcgtggct tggttggtgc tggtacaaac cgtatcaaca tctacgttgt
      481 tcgccaagct actgaaggat tggctcgttt gattgagtca aaaggtggaa acgagaaaga
      541 acgcggtgta gcaattgcct acgatagccg tcacttctca cctgagtttg cctttgaatc
      601 tgcggcagtt cttgctaaac acggcatcaa atcttacgta tttgaaagcc ttcgtccgac
      661 tccagaacta tcatttgcag ttcgtcatct caactgtttc gcaggtatca tggtcacagc
      721 cagccacaac cctgctccat ttaacggtta caaggtttac ggtgaagacg gtggacaaat
      781 gcctccacac gatgcggacg ctttgactac ttatatccgt gcaatcgaaa acccatttgc
      841 agttgaagtt gctgatgtgg aaactgaaaa agcttctggc ttgattgaag ttatcggcga
      901 agctgttgac atagaatacc ttaaagaggt taaggacata aacatcaacc cagccttgat
      961 tgaagaattt ggtaaagaca tgaagattgt ctacacacca cttcatggta ctggtgaaat
     1021 gttggctcgt cgtgctcttg cccaagcagg atttgactct gttcaagttg ttgaagcgca
     1081 agcaactgct gacccagact tctcaactgt aacatctcca aacccagaaa gccaagcagc
     1141 ctttgccctt gctgaagaac ttggtcgtca agttggtgca gatgttcttg tcgcaactga
     1201 cccagacgct gaccgtgttg gtgttgaagt tcttcaaaaa gatggtagct acctcaacct
     1261 ttcaggtaac caaatcggtg ctatcatggc taaatacatc ttggaagctc acaaaaacgc
     1321 tggaactctt cctgaaaatg ccgctctctg caaatctatc gtttcaactg acttggtaac
     1381 gaagattgct gaaagctacg gcgcaactat gttcaacgtc ttgacaggtt tcaaatttat
     1441 cgctgaaaaa atccaagaat tcgaagaaaa acacaaccac acttacatga tgggatttga
     1501 agaaagcttc ggttacttga ttaaaccatt tgtacgtgat aaagatgcca tccaagccgt
     1561 tcttgtcgtt gctgaacttg ctgcctacta ccgttctcgt ggtttgacac ttgctgacgg
     1621 tatcgaagaa atctataaag aatatggcta ctacgcagaa aaaacaatct ctgttactct
     1681 ttcaggtgtc gatggtgctg aacaaatcaa agcgattatg gctaaattcc gcaacaatgc
     1741 tccaacagaa tggaacgcaa cagctatcac tgtcgtagaa gacttcaagg cacaaactgc
     1801 tactgttgct gacggtactg ttacaaactt gacaactcct ccaagtgatg tgttgaaata
     1861 cacacttgct gacggttcat ggattgccgt tcgcccttca ggtacagaac caaaaatcaa
     1921 gttctacatt gcagttgtag gggaaaccaa cgaagaatca caagctaaga ttactaacat
     1981 cgaagcagaa atcaatgcat ttgtaaaata aagacctata aaagatgaga ccaaccaacc
     2041 tcatcttttt tcgtatcaaa tctaagcaat tttagaaact ttatggcata ctagacttat
     2101 caatgaaagc gaggtaatct catggaacaa tttttagata acatcaaaga ccttgaagtc
     2161 actacagttg tgcgtgcgca agaagctctt gataaaaaag aaactgcaac cttctttatc
     2221 ggtcgcaaaa cttgccctta ctgccgtaaa tttgcagata cattgtcagg tgtcgtagct
     2281 gaaaccaaag ctcacattta cttcatcaat agtgaagaac caagccaact caatgatttg
     2341 caagcattcc gctcacgcta tggaatccca actgtaccag gttttgttca tattacagat
     2401 ggacaaatca acgtccgttg cgactcttca atgtcagcac aagaaatcaa agatttcgca
     2461 ggattgtaaa aaatcagcta acaagtctta aaatcacaaa aacgcataat gtaaggtgca
     2521 aaaaccttga tattatgcgt tttattgttc ctaaaacagt tacatcagca tttcattaca
     2581 gaacatttta attttggaag tcaaatcaat ttttaacaat gttttagaaa tcacagtggg
     2641 ctattccata ttcaattatc catattcaat cgctattatc gttttcctag attacaaaaa
     2701 aactacgttt tgctaatcaa aacgcagttt cagccactat tttatcttac tgtccttctt
     2761 ttacttcttt ggttgctaca tcttctccaa accatttttg gctgatttct tggaacttgc
     2821 cgtccttgta aagactagaa aaagcttcat ttatcttctt aaccaaggtt gtatcttcct
     2881 tacgggctcc aaccgcaaaa gcttctgttt ctagtccaac tgtaaagaca ttataatcgt
     2941 ttaaaacacc ttctgcttct aaataatagt ttgcatagac acggtcaatc aatagaccat
     3001 caattcgatc gtttttcaaa tcaatcaagg cttcattaaa ggtttggtat tgattcgctt
     3061 ccttattagc gacaatattc ttcaaaattt ctggatttgc ttcaaagtcc gcataaccag
     3121 atgaaccagc ttgagctcct aatgtctttc cagtcatatc ctttgcagtc gtgataccag
     3181 atgatttctt cgtaaccaat acctgctcat tcttcatata tgagttactg aaagccacct
     3241 tttcacggcg ttcgtctgta gcggaatagc cattccaaat cagatcaatc gttccttttg
     3301 tcaattcagc ttctttcaaa tcccaatcaa tcggttgcca atttaccgtg attccgtatt
     3361 tttcaaaaac agctgtagct aaatcaatat caaatcctgc ataagaacca tctttctgag
     3421 caaatcccat tggaacaaaa gtactatcaa atccaatagt aatagacttg ttagactggt
     3481 actttgacca attatctcca ctagtttcgc tagaattttt cccacaagct actaagaaca
     3541 aagcagtcat cagactgact aatacaagca tccatttttt catccatttt tcctcctatt
     3601 taggttctac tttcaataat acatctgcga tattttcagc aaactgcaaa tcatgggtaa
     3661 ccacaatctg ggtcatccca agttccctat tttgcaagat tagcttctcc acttccaaac
     3721 gtaattctgg atccagggca gaagttggtt catcgtagcc aatgatttct gggtcaatca
     3781 tcatagcacg cgccaaagcc acccgctgct tttgcccacc agatagtgag aaaggatagg
     3841 cctctgcgtg tcctcctagt cctaactgtt ccaagagtcc actcgccttc ttctcagcct
     3901 cttcctgctt cattcccatg gtcttcacag gcgataaagt caaattttcc agaactgata
     3961 gatgaggaaa tagttgaaaa tcttggaaga caaatcccag taggttgcgc ttctgcaatt
     4021 catctagctc taaaggttgt ccattataaa agatttgccc tgaatcaatg gtttcaagac
     4081 ctgcaagcat acgtaaaaga gttgtcttac ctccaccaga aggtccaacg atagccagga
     4141 tttgcttttc aggaatactt agactgaaat cagacaggat ttgtttgtct ccaaagactt
     4201 tattgatatt tcgtaattct aacatagctg ccccctatct ataataactg tactttttct
     4261 caactttttt ggaaataatt gtcacaatcc caattaaaat caagtaaatg gctcctgcca
     4321 agaacatagg aaccagacta gcatcgcggt tagcagctgt tcgactagcc aagataaggt
     4381 ctgaaattcc gagagcatag accaaagaag tatccttgac caaactcata acttcattaa
     4441 agacactagg aagaacgatc ttggtcactt ggggcaagat aatatagcgc actctgtcaa
     4501 aagggctaaa cttcaagacc ttggcagcct catactgtcc tcttggaata gtgtcaattc
     4561 ccccacggaa aatttctgca aagtaagctg catagttgag aacaaaggca ataatagctg
     4621 caggaaggcg gtctaaacga atcccaatac ttgggagcac ataatagata aaaatcagtt
     4681 gcaagagtaa gggggttcct cgcataaccc agatgtaaat gttaatcaga taatggaggg
     4741 gcttccaatg gacttgcaag gcaaaggcaa tcaaaacgcc caagggaatc gaaaatagca
     4801 agaccagtgc aaagacctgt acagtcgtgc tcgcaccatt cagtaaactc ggtaatatct
     4861 caaataaata agacatactg cacctcctaa aagtaattgt tcctattata gcatgaataa
     4921 acaagattac caagtatttt tgtaaaaaga ttctaccata tacaaataaa aaccgtagct
     4981 atcaaaagag ataaactaca gttctatatg tttaaacatt cttacaatct ctcaaacagt
     5041 tcttgcattt gcacatcatc tggaaccagt tttaagtaag tgtgagcatg gacttttgct
     5101 tcttcaaaat gtcccaattc acgcaagaga tagatatagt gttccagaaa ttctggattg
     5161 tccttcaaat ctcctgtcaa ctcttgataa tgctcataag cagtatccaa atcgtccatt
     5221 tcttgataag aacgagcaat catccacttg gtcaaaagat tttctggctc ctcactctgc
     5281 aagtctagaa tatcctcata acgctcctgc tccagataaa tagtggctaa acgaagcaag
     5341 atttcttctg tatcctcagc gtcttctttt gcagtaagga gataattttc tgcaccacta
     5401 gcatcatgca attcataaga aaattgtgaa gcagctagca agaggcgagt ttcaaaggga
     5461 tttttctcta atccttgctt agcgatacgc agggcttctt gaacttgatg ttccttatgt
     5521 aaagcctgac tgtacccata ctcatagcct tcaaagtcag gagaaatggt atcaagctgc
     5581 ttaaagtaga gggtggcttt ttgatattct tcttgatcaa aataaagact ggccaactca
     5641 aaagctgtta agtcatcgta ttctaactcc agggcttttt ctaaaaactc agtagccgtt
     5701 tcaaatttcc ctaactgagc ataggcaaag ccaattcgtt gataggtgga aatgcccgtt
     5761 tgctcataaa tcgagcgatt atctaactgg gcataggctt gaatagccgc ttggtaattt
     5821 tccaactcac tatccaactc tgccaaaccc aatatcaaga gagaatcctc tgagtaggtc
     5881 aaggcctcca ataatttctc acgtgccaca tctgtcaaac cttccagctg gtaaaggtct
     5941 gccttcagag ccaaagacga gacataccag tcactgtcag cttggatttc ctcaagatag
     6001 gtaaaggctt cttctatttg accatcctcg ctagcaattg cagctagatt aagatgaacc
     6061 tctggaaaat cctctacaat tttcaggtaa atttccttgg cctgaggata gaaaccaatc
     6121 ccttcaagat aagttgccaa ctcatacaga agatcacttg aatcattttc taaagctttg
     6181 gcgaaataat gctcagcctt agttaaatct tgctcctcca aagcctgtaa catctgttga
     6241 ctattgttca ctcttgactt cctcaccctc taattcatat agaccactga ctaccttata
     6301 ccattcgaaa atggctgaaa tgacaacctt agcagaggca taaaccggaa taccaagtaa
     6361 aactccccag ataccaaaca tagatcctga agttaacaaa acaaagagaa cattaatagg
     6421 atggatgttt aattgacttc ccaaaatcaa tggagagaca aaacggcctt caatagtttg
     6481 ttctacgata aagacaatca ctactttcaa aagcatgact ggaccagcaa tcaaacccaa
     6541 tactagagca ggaagcatgg ctagaaagct accaagataa gggaccagat ttaaaatacc
     6601 agcagtaacc cccagcgtaa ccgcatagcg tagaccaata atcttgaaga agatgataaa
     6661 cattactgct acaataatag ccactgtcac ttgccctcga acatagttgg acaactgttg
     6721 attcacatct gatagaactt gtccaacagg ttccttcaat tttcttggaa tgaattgggt
     6781 caaatagtta cgcaagcctt tcccatcacg caagagataa aagagcatga aaggaacgat
     6841 aatcaaggca acaatcactt gagaagctcc gctaataaag gcactcaccc agttgactgc
     6901 ctgagatgaa accttacttg ccaaaactgt agcctggcta gaaaaattgg tcaaaacttg
     6961 ctctaattga ggtctgaaat catctggcag gtgctgggct accaatccat taacaatcct
     7021 atctatatct tctaagtaaa caggaacgtt tcttgcaaag gtcaaaacct gacgttgcag
     7081 atttggaatg gcgactgcca agccccaaat gataaagaga gcgatgataa caaagacaat
     7141 agtgatagct ataacacgat taaccttatg cttctccatc caatcaacaa taggattcaa
     7201 caaataatat aacaaaccag acaaaatgac tggcaacatc acaactgcta aaaagtctaa
     7261 aacaggtgaa aatagaaaac taatcttact taaaataaaa agattcaatc ccaataataa
     7321 ggttactaaa aataccgtaa ttgccttgtt atctaaaaac cacttgaaaa accaagatag
     7381 gctaaaatgt ttctcttttt gctccataaa tacttccttt ctattgttct ctcattatac
     7441 catttttgaa acaaaataac tcttttttaa agtgcttaca tctaattgaa tgtctttaat
     7501 ttgcttgttt ttgtgatata atagtcttat ctttacacag aggtatagta atgaaagaaa
     7561 ctgtttattt tggaacttat acacgtcgta cttctcaagg gatttacaag gcagactttg
     7621 atacagaaac tggtcagctt tcaaatctag aactttttgc agctgagcca agtccaacct
     7681 accttgcctt tgaccagcac caacatttat acactgttgg tagccaagac gataaggggg
     7741 gaattgcagc ctatcaaact gacgggactg tgttaaatca tgttgttgaa gaaggagctc
     7801 cccactgtta tgttgctgtt gatgaaaagc gtgatttggt ttacgcagcc aactatcaca
     7861 agggacaagt ccttgtttat aaacgccagg aagatggtag tcttctactt agtgatatgg
     7921 atcaacacag tggccaaggt ccacatgaaa atcaagcttc cccccatgtt cactatacag
     7981 atttaacacc tgaccactat ctagtgacct gcgacttggg aactgaccaa gtcatcacct
     8041 atgacctcga tcaagaagga aaattatcta agctctatac ctatcacagc aagccaggag
     8101 caggctcacg ccatatcatt ttccataacc actataaaat cgcttatctc atttgtgaac
     8161 tcaatagtac tatcgaagtt ttaatctacg atggcgttgg cgaatttgta cgtatgcagg
     8221 ttatttcaac tttaccagaa gcttacgaag gctttaatgg aaccgctgct attcatctct
     8281 ctaaagacgg taaatacctc tacgcttcta accgtggcca tgattctatc gcagtatata
     8341 ccatccttgc ggacggtagc ttagagttat tagaaatcgt tccaacgcat ggtcagactc
     8401 cacgtgattt tgatttgaca cccgaccaaa aatttctcat tgttgtccat caagactctg
     8461 acaatgcaac tgtctttaaa cgtaattgtg acaatggtcg tctagcagaa ctctccaacg
     8521 acttccatgt tcccgaagca gtctgcatcc gttttgctcc ttaaaacacc ataaaaaatg
     8581 aacttggtat tttcaagttc attttttctt atagtctatt tccgacatta atacggttaa
     8641 tggcacgttg caaagcaatc ttagcacgac gttcttggtc aatcaaatgt ttgtcttgtg
     8701 cttcttcaat tgcacgttct gcacgaagtt tggcacgttc tgcacgactg atatcgatat
     8761 cacgagcacg ttctgcagag tcagcgacga ttgtgatcat atcattggca atttcaataa
     8821 cgccaccgtt tactgcaatc cagttcacgt gatctttatc atcgatacgt tttaccttta
     8881 cttcatcaac tgctaaaacc gcaatcatat tttcatgtcg tggcaagatc cccatctcac
     8941 catccagagt tcgaaccgat acatagctgg catggtgatc atagacgaga ccatctggtg
     9001 tcacgatctg gacagttaac tgagccatag gtcacctctt aaaatcccat tttttcagct
     9061 tttgcaatca catcttcgat agaacctaca ccacggaagg catcttctgg caagtggtcg
     9121 tatttaccat caaggatttc cttaaagcca cgtacagttt cagcaactgg aacataagaa
     9181 cctggctgac cagtaaattg ttccgcaacg ttgaagtttt gtgacaagaa gaactggata
     9241 cgacgggcgc gagcaaccaa ggtcttttct tcatcagaaa gctcatccat accaaggata
     9301 gcaatgatat cttgcaattc atggtaacgt tgaaggacac gttttacttc agcagcaact
     9361 gcatagtgct cttctccaac gatttcaggt gccaaggcac gtgagcttga agcaagtggg
     9421 tcaacggctg ggtagatacc caattgtacc aacttacgtt ccaagtttgt tgttgaatcc
     9481 aagtgagcga aggctgttgc tggcgctggg tcagtatagt catccgctgg cacatagata
     9541 gcctggatag aggttacaga acccttcttg gttgatgtga tacgttcttg caattgaccc
     9601 atttccgtag caagtgttgg ttggtaacca acggctgatg gcatacgacc caaaagggca
     9661 gatacttctg aaccagcctg agtgaaacgg aagatattat cgataaagag aagcacgtct
     9721 tggccttcca catcacggaa gtattcagcg attgtcaaac cagtaagggc aacacgcata
     9781 cgtgctcctg gtggctcatt catctgacca aagaccatgg ctgttttctc gataacgcct
     9841 gattctttca tttcccagta aaggtcattc ccttcacgag tacgttcccc aacaccagca
     9901 aatactgaaa taccaccgtg ctcttgggca atgttgtgaa tcaattcttg gattaagaca
     9961 gttttaccaa ctccggcacc accgaaaagt ccaactttac cacctttaag gtaaggggca
    10021 agaaggtcaa taaccttgat ccctgtttca aggatttcag aagaggtaga caactcatca
    10081 aaagttggag cttttttatg aattggctga cgctctgcgt cttctgtaaa aggagcttcc
    10141 aagtcaatgg tatctcccaa aacgttgaag acacgtccca aagtttcttt acctactggt
    10201 acagagattg gacgacctgt gtccaatact tccattccac gagtcaaccc atctgttgat
    10261 tccatggcga tagtacgaac cataccatct cctaactcca aggctacttc aaggacgatt
    10321 tttgtttttc tttcgtcatt tttgtagacg acaagtgcat tattaatctc aggaagtttt
    10381 tcccctgctg caaacaaaac gtctacaacg ggaccgataa cctgagcaat tttacctgaa
    10441 ctcatctcct tctcctattc tatataagat actgtcggtt cctagctcaa ctaggtccta
    10501 agttcatttt catacgagct ggactagagc ctattctaag gcactagcac ctgctacgat
    10561 ttctgtaatt tcttgtgtaa tagccgcctg tctggcacgg ttatactgaa ttgtcaaatc
    10621 attgatgact ttcttagcat tatctgtcgc tgtttgcatg gctgtcatac ccgcagcatt
    10681 ctcagctgtc ttggcatcga taatggcacc gtaaatcata ctttctgcaa actgaggcaa
    10741 caactgctcc agaatttctt ctcggctggt ttccaattca aaagtcaagc tgtactcttc
    10801 atccgcttca tttggatcca agtcaacaat cggaagcatt tgttccacac gcatttgact
    10861 ggttagcgta ttgacatggt ggttgtagca aacataaagc tcatcaaaga gttcattttg
    10921 gtacatttca acagtttttg aaataatctt acgaacttga tcaaagctag gttggtctgc
    10981 caagccacgt aattcataaa gtggttgaat accgcgagcc ttaaagaaat cagctcccat
    11041 cccaccgata cagatcattt caaaaccttt accgtctggg tggtattctt ctttcaactc
    11101 cataacagct ttcaaaatag aggaattata acctccaacc aaaccgcggt ctgaagtgat
    11161 aacgatatag cctgtcttct tcacagaacg gctaatcaac atcggattag ttgaagcacc
    11221 agctccatta ccatgaagga tatctgtcaa aagtttacgc actttctgag cgtaaacttg
    11281 gaagttgcga gcagcttctt cagagcgacc tagcttagca gccgatacca tttgcatggc
    11341 attagtgatt tgactcgtat tttttgttga ggcgattttt gttttaatat catttagaga
    11401 cactgccatc tgacacctct attcttattg gaagctagat tgattgagaa actctgtaat
    11461 cgcagcatcc aagactgctt cttctggcaa gtcttttgta tcacgaatgg tttccaaaat
    11521 ctctggatgt tgagcatcaa agaaggcatg gaactcttcc tcgaaacgaa caatatcatc
    11581 tactggaaca gtatccaaga aaccatgtgt caaagcataa agaatggtta cttgtttctc
    11641 aacaggtaat ggtttgtgaa caggttgttt caagacctca acggtacgac gtccacggtt
    11701 caacttagcc tgtgttgctg cgtccaagtc agaaccaaac ttagtaaagg cttccaactc
    11761 acggtatgaa gcaaggtcga tacgaagtgt accagcaacc ttcttcatgg ctttgatttg
    11821 tgcagaacca cctacacgag atacagatga acccgcatcg atggctggac gaatacctgc
    11881 attgaagagg ccatcgccaa ggaagatttg tccatcagtg atagaaatca cgttggttgc
    11941 gatataggct gagatatctc ctgcttgtgt ctcgataaat ggtagggctg taattgatcc
    12001 accaccaagt tcatcagaaa ctttagctga gcgctcaagc aaacggctgt ggagatagaa
    12061 aacatcccct gggaaggctt cacgacctgg aggacgacga agcaagagcg acagttcacg
    12121 ataagctacc gcttgttttg atagatcatc atatacaatc aaaacatgct taccttgata
    12181 cataaattct tccgccatag caaccccagc ataaggagct aggaagagca atggagatgg
    12241 ttgtgaagca gaggctgtca caacgattgt gtagtccaag gcaccgtact gacgaagtgt
    12301 ttctacttgc gtacgaactg ttgattcttt ttgtccaatc gcgacgtaga tacagatcat
    12361 atcttgatct ttttggttca agattgtatc aatcgcaatg gttgttttcc ctgtctgacg
    12421 gtcaccgata atcaactcac gttgaccacg accaatcggt acaagggcgt caatagcttt
    12481 caaaccagtt tgcaatggtt ctgaaacaga cttacgttgc ataacaccag gagctggtgc
    12541 ctcaactgga cgagttttat cagtgtggat ttctccaaga ccgtcaactg gacgaccaag
    12601 cggatccaca acacgaccaa tcagactttc acctacaggg acttccatga ttttccctgt
    12661 acggcggatt gtatcgcctt cacggatatc tgtaaagtca cctaggatga taataccaac
    12721 gtctgttgac tccaagtttt gagccatacc ataagagccg ttttcaaaat tcaacaactc
    12781 tccactcatg gcattttcaa ggccgtgagc acgcgcgata ccatccccga tataggttac
    12841 aacacctgtt tcagtcacat caaaattggg tttgaaattt tcaatttgtt gcttaattaa
    12901 agcgctgatt tcttgtgcgt taattgccaa aagaacacca ctttctattt caaattttct
    12961 ttaacaactt taagttgttg tttaatactc acatcaattg tcttgtgatt ggcaaaaatg
    13021 acaaaaccac caatgagact ttcatcgatt tgttctttta cactccttac tttcagagac
    13081 atttttttct caatcaaagg gagcaaacga gtcttctgtt catcagttag aggatgagca
    13141 gacgtaatcg tcacttcaaa tcgatttgtt tctttttcaa gtcggttcaa gcaatctaca
    13201 agcacatcat aaaaaagatt tgctctgtga ttgtaggcca gaacctggat aaagttttgt
    13261 aataaaggtg acacagaatc ttggaaaaaa gcaattgttt tttccttatc cgactcgtct
    13321 actgccactt gttttaaaaa agaaggcaga cctgtttttt caacaacttg cttgatttga
    13381 gtcaagtctg aaaagatacg gtcttcttct cctttttcaa gtaccaattg gacaaaaggc
    13441 atgctgtatt tttcaattac ctttactgtt ttcttgtcca ttaagcttct cctagctgat
    13501 cgatatactg atcaatgagt gctttatggg catgactgtc aaggttttgt gagatgattt
    13561 taccagctaa gctgatggtc aaatctgcga cctcaccctt aacactctgt aaagcttcta
    13621 ctttattttg agcaatttct tgattggctt tttcttttaa gtgtcctgct tctagtttag
    13681 catctgctaa gatattagcc ttactttgct cagctgtttc ctttgcattt tcaatgattg
    13741 tcttagcttc tttacggcta ccagccaatt catcttcgcg tttttgagcc aatacttctg
    13801 ctttttgacg ggcttcttca gctctatcaa tatctgaagc aattttttca gctctttctt
    13861 cgaaaatgcc tgtaatatta gaccatgcaa attttttaat caagactagc aaaagaataa
    13921 aagagccagt gattaaaata aaattaccaa ttaattcacc tactgttacg tgcatcagtt
    13981 actcctttct attcctcttc aatattaatc ttattcccta aatacacaga tgtcaaaaga
    14041 gtaaaaacat aagcttggat gcaggaaata aagacagaaa atgcagtcca agccaaatta
    14101 gctccaaagg ctactggata ccaataaata gcttggtggg aaagaagaag taacaaactc
    14161 gtcatgacct ctcctgcaaa gatattccca aaaatccgca aagccaaaga taagaagttt
    14221 gtaaattctt ccaagatatt catcggtatg acaaaaacag gactcataaa agattttata
    14281 ctttttttaa atccacgacg acgaacgctt tctatatgtg tcaacaaaat gacaagaaaa
    14341 gataaggtta agtcatactg taaattagcg gttggcgaac tccaccagtt agtcccatcg
    14401 atcgtttgaa gctttgtcat taagccaagg ttattggcaa tcaccatgaa aaggaataaa
    14461 caaaggaaaa agagtgagta atctttcatg tagcgcgaac caatgttagg ttctgtaaat
    14521 ccaataacaa agtcatagac atactcaagt acattttgct ttcctttggg tttcaaggtc
    14581 atattgcggc ttgcccaata aataaagaca aaaataactc ccacaatcaa caaagtcatg
    14641 gctaacatag tcagattgaa gataacagga ccaatagaga tgattggatt aatactttct
    14701 tccatctaaa atcctccctt ttcttctcgt tccatgtatt tatttgataa taaatgagaa
    14761 gacaagagtt acaaagaaag ttccttcaat aaaggcaaca cctaaaaaca tcaaactacg
    14821 aaactcagaa agcatatctg gttggcgtgc tactgattta aacagtccat tcatcaataa
    14881 accttcaccg acagatacgc ccatacaggc aatacataag cctaaaaatg ttaaattcat
    14941 aacaaattct cctttaaaat aaaatttact tacttagtgt agtcctaaaa tttaaatttg
    15001 tcaactttta accgctattg gaagcgttta ataaaaatta tttccatttt gctaaatttc
    15061 aagttcaagt tagccatcca gaagtcttct ctgggtgact tgtagtccaa gcatttttta
    15121 ggatagttgt taatccactt ttcgatgaat gcgacttcct taggagtcat tttcttggtt
    15181 cccttaggta accatctacg aatgaacctg ttgtgattct cattagttcc cctttcccaa
    15241 gaggcatagg ggtgcgcata ataaatgtgc tcctcagaaa atacatcaga caagcgattg
    15301 aattccgttc cattatctgc cgtgatggaa agaatcttgt gttgttttaa gatgagtttt
    15361 agagcctgat tgaccacctc agcactttta tttggaatca atcggatgat ctgatgtcta
    15421 ctctttcgat ccgtcaagac aagcaagcag tagtttttcg atctcgtaag tagaaccgta
    15481 tcaatctcat aatgcccatt ctccaagcga agattgatag cttcaggccg ctgtgcgatg
    15541 gattgaccag caggtttaaa gttggtgcta gcctgtttct taagcacttt tccttttcta
    15601 gggtaaagca gatcctgctt gcttaacccc aattttccat gatgaatcca atagtaaatg
    15661 gttgaaattc ccacgttaac ccctttagcc atcaccatca tttcaggcga aaatttttgg
    15721 ttatgatagt ggagaatctt ttcctttagt tcctttgtca agcttgattt cttgaccgag
    15781 cgcttgcgat tgttttcata agactgttga gcatagtcgg cagaataaac ctctttgaag
    15841 cgcccttttc caagacattg tcggactgtc ccacgcttga tttcagtgtg gatagtttga
    15901 ggaacttttc caagcagaga ggcaatttct ctatttgatt ttccttcttt tttccatctt
    15961 tcgattaagc gacggctatc gattgtcaaa tgttcgcctt ttgtagtata atggttttgc
    16021 atctctgtgc ctttcttgtg tttgtggttg aacaacaagt ataacacaga ggtgttttct
    16081 tatgcctaca agagctttca ttatttccat tttctttcgg atttcactct attctgaaaa
    16141 acttgtgtat atttactgaa gctagcaagt cttacctgta aatttaatga aagcaacaca
    16201 aaatccgaga gggaaatctc ggattaatgt caatttaaaa agatagagag tttttagttt
    16261 aaataaattg ttttaaaata tcaacaacat cacttctttt cttaacctga taagccttga
    16321 ttcctaattt tggagctacg attatattgt cctcaatatc gtctagaaag acacaatttc
    16381 taggttataa ctggtattta tcgatagtta ctcatatata tcagtccact tccatactca
    16441 ccttacagat tcttttggta ataatatctt tgcctaatgt agagataatc ttgcaaagaa
    16501 aaaacttcct tgtagccatg tttctgataa aagtccggtg cctggaactg gtaagtattg
    16561 acaaaggcaa aacaacaatt tcgattctta gcttcacttt ctgcctgttg caatagtttt
    16621 gaaccgattc cttgccctcg cagttcctct tttacaaaca aatactcgat ttctagccaa
    16681 tttccaaaag tctctgctat caaacctgcc aggagattgc ccttttcatc ttcgacataa
    16741 agattaagtg gctcactttc agcctcttct ctttttgaac ggttataaac acgaatcaga
    16801 ttccctattt tttgcgattt atgtgattcc ttattttcca atctaaagta tagtgaaatg
    16861 aaataaaaca tgcgcaaatc gattaaggaa tttaatctaa tttctaacaa tgtcttagaa
    16921 atcaaagtgt actattttaa cttcaatgca ctatacatct aatactcaat aaaaatcaaa
    16981 gagcaaacta ggaaactagc cgcaggttgc tcaaaacact gttttgaggt tgtagataga
    17041 actgacgaag tcagtaacca tacatacggc aaggcgacgc tgacgtggtt tgaagagatt
    17101 ttcgaagagt agcaaaatgg aaaaaggagt gagtgaagca catcgcctcc ccactccttt
    17161 ttctgttttt aggctgtttt ttcaaccttc aagattttta catcatagct accaacaggc
    17221 gtttcaatgg ttgctgtatc acctgttttc ttgccaatca aggcctgccc aattgggctt
    17281 tcatttgaaa ccttacctgc aaaggcatcc gcaccagctg aacctacgat aatataaact
    17341 tcttcttcgt cctcaccaat ttcttggatg gtgactgttt taccaatcgc tacttcgtcc
    17401 tgggcaactg cgtcgctatt gacgatttca gcatagcgga tttttgtttc taagctagag
    17461 atttgtcctt cgacaaaggc ttgttcatcc ttagctgctt cgtactcact gttttctgaa
    17521 aggtcaccgt atgaacgggc aatcttaatg cgttctacca cttctggtcg acgaaccaat
    17581 ttcaattctt ctaattcttt ttcaagtttt tccttttcct caagggtcat aggatatgtt
    17641 ttttctgcca tttttctcaa ctttcttctg ataatatttt ctaaagaaaa ttatgtgaag
    17701 tatcacataa ttttagtttg tttagtttaa tttgctgttg acatgttcag cgacattgcg
    17761 gtcgtggtct tcttgattgt tagcatagta gaccttgcct tctgtgacat ctgctacaaa
    17821 gtagaggtta tcgctcttag tttgattgat gcttgactca atcgcatcca gacttggact
    17881 atcgactgga ccaggcatga gacctacatt tttataaaca ttataaggtg aatcaatgtt
    17941 ggtatcaatc gcaacatcct cagctagact gatattttgc cccagttttc cttgggcata
    18001 caagattgca atattacttt gaagtggcat atcacgattc aaacgattgt agaatacacc
    18061 tgcaatgagc ttacgatctt ctgtcttggc accttctttt tcgaccaagg aagcaatggt
    18121 caacaactca ttgacagtca agtttttaga tttgatagta ctatagtaag gagataggtt
    18181 cttatccata gcagctaaca tctcatcaat caagctctca atagttgtgc tttccttgat
    18241 agagtatgta gctgggaaaa ggtatccttc caaacgataa cgcgcaccgc tgtcttttac
    18301 aggcaaactt tccagtaaag taggatattt cgctactgct tgactgataa acgtctcatc
    18361 ttgaacttta gccaagaaag cctccgctgt caaagactct ttgaagtcac cttgcaattg
    18421 acccacagtt tgagcaatct gatccaaggt ataaccttct ggaattgtca aagtcgcaag
    18481 tacaggttct tgcggttcat ctgttccacc tttttgcaac tctttgagta agtcttctgt
    18541 actcatactc ttttgcaaat tgtagtaacc tgctttcaag tcggtataat ttttatactt
    18601 ggcataaaaa ctaaaaatca gaccatgctt taccaaacca gctttttcaa gcgtcgtacc
    18661 gatttcttga acgtttgaac cttctggaat tccaaccgtc acatatttct tagaattagc
    18721 atcgataggt aataaggaat ctagcacgta ctggtaacca aagtaaccac ctgctgagag
    18781 caaggcaagg aatacaagga atgaaatcac aaaagctttc acatgtgact tcttctcttt
    18841 cttaggctta acgggttttg ctccttctct acggctacga cgtgatgtat ctctgatgat
    18901 atccactgtt tctgtagcag gcgtaggtgt ttctggacct gcttgttctg cttttttctc
    18961 tgccgtcgta taggaaacag ctacccttgt tggggtttca ttgtattctc tttcaagttt
    19021 cttaggtcta acaggacctg gacctggtct tgatccactt tcttccgctg gagaagaagg
    19081 tacatcttga cttggatgac ttggaacacc aggagtttct ctttgaatct catctgctgg
    19141 agaagctggt acaccttgac ttgggtgagt aggcacggta ggagcttttc tcataatctc
    19201 ctctaccgtt gacaaggaat cagccatgag ttcttcagct gaaggttcat ttgcaggagt
    19261 gcgaactact gcctcatctt ctttcagaac ttcatcatag ccttttactt tttctaaatc
    19321 tctcagaatc tgctctttaa agcttaattt ctcttcttct cttgactttt cactcaaaag
    19381 tttttcctcc ttgttgataa tccataatat tatatcttaa aagtccaaaa aaagcaatct
    19441 atgatacttt tcctaactta ttttttcatt tcccagacca tatcatacca tgtttcccct
    19501 gcaaaggttg actgggactg gccttcgttg acaaatccat gtttttcata ataggcgatg
    19561 agatagtcat gacaggttag attaatgcca tctctctcat cttcaagagc aacttctttc
    19621 aaggctgtca gcaatttctg acccagtccg agtccctgtg cctccttggc aatagacaga
    19681 caggtcacag agatataacc accaggctca tgactatagt cttttatttc ttctgtaaaa
    19741 gactggtctt gcagatggcg gtgcaggcca actggtcctt cgatataacc catgattctt
    19801 ccttcttttt cagcaaccag aaaagaggtc tgaatttctc tcaaatgtgc ttcaaagaca
    19861 gaaggaggaa tggcttcttc gaccgaaaaa ttttcaaatt caagttcaac aatccgatcc
    19921 aaatcttcta atcttgcttg tctgattttc attgttcctc cagataaaag ggattaaacc
    19981 aaatcatact atagccctgg ctagttgcat agagcaaaat ttcttcttca tcaacaaaac
    20041 cgttcatttc aaaataggaa agcagctcat caggactctc caaacgaatc cctttgtaat
    20101 ccagctcaac tgccacctct ttcaaggctg caagaagaag tgttcccagg ccctgtctct
    20161 gatggtcaga ctcgatgact aaagaatgta cttttagaca ttgcggattg tctgactggg
    20221 gacttgataa aatataacct aaaagttgat tttcatccct agctagaaga aaggtatccg
    20281 cacacttacg gatactttct tctaaaatat gggaaagttg ctgcttttca gctggaaaag
    20341 acgaggtctg aagtgcccct atctcaggca aatcaaactt gcttgcctga atgatcttaa
    20401 ttggaatttc catgggaaca tcctattgaa cattgcttgt caagttagac aagagacgct
    20461 caaatgagta ttcataggtt tggatgtctc ctgctcccat aaagacgtaa acagcattgt
    20521 catggtctag gagtggagaa acattttcaa cagtaatcac ttggtgtttt ttgttgattt
    20581 tattggctag gtcttctacc ttaacgtcac catgatctac ttcacgagcc gagccataaa
    20641 tttgcgctag ataaacagca tctgcttggt ttaaagcatg ggcaaagtcg tccaacaggg
    20701 caatggttct tgtaaaggta tgcggttgaa agactgctac aatttccttg cttgggtatt
    20761 tctgacgagc cgcatccaag gtcgcaataa tttctgttgg atgatgggca aagtcatcaa
    20821 taatcactgt atcattgaca attttctcag tgaaacgacg tttaacaccg gcaaatgttt
    20881 tcaagtgctc acgcaccaag ttcaaatcaa atcctgctgt gtaaagaaga ccaataacgg
    20941 ctgtcgcatt catgatattg tgacgaccaa aggttggaat gtggaattgc cccaagtttt
    21001 gtccacggaa atgaacggtg aaggttgaac cagttgttga acgaagaaga tcactagcta
    21061 caaagtcatt gccttcagct tcaaaaccat aataataaat tggtgcatca gacgtaatct
    21121 tacgcaattc agcatcttca ccatagacaa aaagaccctt ggtaatttgt ttggcatagt
    21181 cgttaaaggc attgaaaaca tcctcgagac ttgtgaaata atctggatgg tcaaagtcaa
    21241 tgttggtgat aatagagtat tctgggtggt aaggcatgaa gtgacgctca tattcgtcag
    21301 attcaaagac aaaatatttg gcattagccg aaccacgacc tgtcccatct ccaatcaaga
    21361 agctggtatc tgtaatgtga gacaagacat gagacaacat acctgtcgtt gaagtttttc
    21421 catgtgctcc tgctactccc atgctaacaa agtcacgcat aaagctacct agaaactcat
    21481 ggtaacgttt gtagctgata ccattttggt ccgcataggc aatttcgacg ttgttatctg
    21541 gacgaaaggc atttccagcg ataatttcca tatcaccgtc tagattcttt tcatcaaaag
    21601 gaagaatggt aattcctgcc tgctcaagac cgcgttgggt aaagtagtac ttttcaacat
    21661 ctgatccctg aaccttgtgc cccatctggt gcaacatcaa ggccaaggca ctcatccctg
    21721 atcccttaat tccgataaaa tgatatgtct ttgacatgtt ttctccccta ttctgtcatt
    21781 ctggtcagat tcaactcttg ggcaacccga cgttcttgtt ctgtttgttt acttttttta
    21841 ttgtagattt ggctcttctt tagaaaatca taattgtttt tctttggagc aggtgctgac
    21901 acttcttcat tcttggtagg gatagaatga acttcttccg ccaagatata atgagactgg
    21961 gtcaattttt ggctatattt gacaaattca ccaggatttt ccttttggaa aggagttgtc
    22021 ggttgattgc cctgtctaac tagactgggc tgagaatgac gtctcgcaag gctgaaatcc
    22081 tgagttaggt agttagcaga gcgtttcttt ttcaagtccg cacgcgcttc ttcacgcgcc
    22141 acctccgcat agctctttcc ttctttttta acccctaaag gagccttttt aggtttttcg
    22201 acttgctttt caatcggttt tactggtttt tcttcagtaa taggagccca ttctaaataa
    22261 tttttatctc gatactcacc cttgatatta ctgatcagat cagactcatc atagagattc
    22321 atgactggca tttcagtcaa catgacctcg tcatctgaca ccaatggaaa tcgttcttgt
    22381 ttcattttct atttcctttc aacacttcat tatagcgtat tgtcttgatt tttcaagtgc
    22441 tggcttcaga aattcccaaa atttctctaa tttctgctag ggtcagacta ccacgtgact
    22501 ctgtgccatc caatacttgt gacaccagat gtttcttttg ttcttggagt tcctgaattt
    22561 tttcttcaat ggttcccttg gtcaccaagc gatagacctc aaccgtttct tcctgaccca
    22621 tccgatgggc acggccaatg gcttgcgctt ccaccgcagg attccaccaa aggtcaacca
    22681 agatcactgt atctgcacct gtcaggttca gaccgacccc accagccttg agggaaatca
    22741 gaaaggcatc tctttctcct tggttaaagg ccttggtcat gtcttgtctt tccttggctg
    22801 gggttgaacc cgtaatttta aaggatgtca ggcccaagtc tggcagttct tgttcaattt
    22861 tttccaacat tcccttgaac tgagagaaaa tcaagacacg gtgtccgccg tctgccacct
    22921 gtaccagtag atctcggaga ctatctagtt tgccgctggc tccctgataa tcttccataa
    22981 acagggcagg agtgtcacat atttgacgca agcgcatcaa accagataaa atttccacac
    23041 gacttcgctg aaattcctgt tctgacactt gagccagatg gtctcgcatc tgttgtaact
    23101 gggcaaggta aatagccttt tgctggtctt ccagttcatt tttataaacc acctcaatca
    23161 agtctggcaa ttcagtcaga acttcttctt tcttgcgtcg catcacgaaa ggcttgataa
    23221 actgagccac tcgctctgct ggcaatttca taaattcttt cttgcttggc aaaagtccgg
    23281 gcatgacgat ttggaaaata gaccacaact cacccagatg gttttcaatc ggagttcctg
    23341 acaaggcaaa gaccgacggc accacaaatt gtctcaaggt ctgggcaatc ttggtctggg
    23401 catttttcat gacctgagcc tcatctaaga aaaggaagtc aaaggccatc ccctgataaa
    23461 actcactgtc ctgacggaag gtggcatagc tagtcacata gatttgatgg ctctcggcaa
    23521 gaatctcctc acgacttgct ttcaaaccat gaacaacagc cacatccaac tgtggggcaa
    23581 atttctgaaa ctcatctgcc cagttgtaaa tcaaacctga cggagcgaga atcaaaaccc
    23641 gactttcttt tgtcacttga ctagtcaaaa aagcaatggt ctgaagggtt ttcccaagtc
    23701 ccatatcatc agccaaaatc ccaccaaaac cataatgatg gagcatctgc aaccagccaa
    23761 ttcccttttc ctgataatct cgcaagtcag cctgaacctg agttgcctgt cgaggaaagt
    23821 cctctggatg tgtcaaatcc tgggccagat tctggaattc ttgtgaaaaa gaaacacggt
    23881 ctcgcccttc aaagagatga gctaaactgt aggccaagga tttccgagcc tgcaaggtcc
    23941 catcttttaa ttcaaattgc cccagttcct gtagattttg gcgaattttc ttggtttctt
    24001 catcgaaaaa gtaaacttga ttagacgaat caatataaaa atcctgattg gcaaccaagg
    24061 cctgcatggc ttggtcgatt tcctcctggg caatatcttg aaaatcaaac tggatttcca
    24121 agagacctcc cttggaggca atctgcacct gaggactcgc taggctataa agctcttcta
    24181 gtttatctga taggtcaaca tgcccgagtt tttcaaagac tggaatgata tcatgaaaaa
    24241 aatgatagac agactccgct tttaaggcct gacgccaaga ttgaaaatcg gcttcaaagc
    24301 ccgcagccaa acagacttgg aaaattcttt cttctaagtc cgcgtcactt gaaaatggta
    24361 attcttctag ctcttgtcgg ctagatacct gtctatttcc ataatcaaac tgaatttcta
    24421 aacgaatccg attatcttct tccctgtcaa agtaaaaaga gggcgcaaaa gttttgattt
    24481 gtagacgttc tggagctgaa acggtgccca tctggataaa aagagtcaga caggaggcca
    24541 atttgtctcg atcactgcta tcaaattgca ggtatttctt tccttgttga cccacaggta
    24601 acgctttaat ttccttgaga agacgcatct gctggtctgt taaaaaataa acctgacctt
    24661 tatggaaaag tactgctccc tgataaaaga cattgaccct aggactctca ctgatttcca
    24721 tttcaaaata gtccgagtat tctgttactg caaaggcaaa tagattggca tcagcatgca
    24781 tatcctgaaa aagcagggtt tggtagctat ccacttgatg gtcaaattga aaatggggca
    24841 aggccatcag taaattcaca ccctgctcaa aaaaggtcag agggaaaaag aggtgccgac
    24901 cttggttttg gaaaaagagg tctgaaacca gcccttcctc cgttagtccg tgcaagaaag
    24961 tcaaaagttc ttggctggca tcatcaaagg cttcccaaga aagagactcc tcataaatct
    25021 tgccaatcat atacgacttt ctctgctcga caatccttaa aaaaagtgga atatcccgaa
    25081 tgacatagta tttttggcta ttgatttggc cgattctcag agtccacaag atatgattgg
    25141 ttcctgcttc cacctgaccc acagctgata actcataggc gcattctgat tttggagata
    25201 aaattcgatc caaaaacttg ccacccaagg tcaccttggt ttcaacagcc tctttttctt
    25261 catgaccttc ttccagactc cacaagattt cctgaccacg ctcatcattt ttcagaaaat
    25321 gctctagcgc tgccaaatgc acacagtaac ccctcttttg aaaaaaatca caggcacaaa
    25381 aaaccaaatc atcctctaaa ctatagcgca gttcttcttc tgcaacgcga gcgtagagcc
    25441 gattgttctt ttccttgatg atatcaacct taccagtttc ataaagggca acaccttcga
    25501 tacgaatttt ccccggaatc aatttagcca tattttcacc tttaccttat ctttttatta
    25561 taccatattt tcgcctatga aaatagcctt ctaggaagac ttttctccta gaaggctgga
    25621 tttttaacgt ttcccaaatt tcaagttgaa gttagccacc caaaagaaat tcacttggcg
    25681 acttgtagtc caagcatttt ttagggtagt tgttaatcca attttcgata aaagctactt
    25741 ctttcggagt cgttttcttg gttcctttag gtaaccatct ccgaattaat cgattatgat
    25801 tttcatttga acctctctcc catgaagagt aagcatgtgc gtagtagata tgttcctcag
    25861 gaaatacctc agacaatcgt ttgaactccg aaccattatc tgcagtaatg gacagaatac
    25921 gatgctcccc taatagtaac gtaagcgcct gattgacaga ttcagcagtt ttatttggaa
    25981 ttaaccttat aatttggtgt ctgctccgcc ggtcggttaa gactaacagg caataatttt
    26041 ttatcttagt cagtaggacg gtatcaattt cataatgacc attttccaag cgaagattaa
    26101 taacgtcagg acgttcttcg atagatttac ctgccggctt aaagttcgga ttagcttgct
    26161 tcttgacacc tttccttttt ctgggataaa gcatgtcggc cttcgtcaat cctaaatgac
    26221 cattatgaaa ccagtagtag atggttgaaa taccaacttt cacttgcttc ttgttaacca
    26281 tcatttcagg cgaaaatttt tgcttatgat agtgtaagat cttctctctg atttc
//
LOCUS       DAVLHB010000025        26269 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLHB010000025 DAVLHB010000000
VERSION     DAVLHB010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.025"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            64..561
                     /locus_tag="VXE36_001200"
     CDS             64..561
                     /locus_tag="VXE36_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0779512.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            561..2216
                     /gene="dnaX"
                     /locus_tag="VXE36_001201"
     CDS             561..2216
                     /gene="dnaX"
                     /locus_tag="VXE36_001201"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0779513.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2244..2438
                     /locus_tag="VXE36_001202"
     CDS             2244..2438
                     /locus_tag="VXE36_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0779514.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2588..3358
                     /gene="sufC"
                     /locus_tag="VXE36_001203"
     CDS             2588..3358
                     /gene="sufC"
                     /locus_tag="VXE36_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0779515.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3386..4648
                     /gene="sufD"
                     /locus_tag="VXE36_001204"
     CDS             3386..4648
                     /gene="sufD"
                     /locus_tag="VXE36_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0779516.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGDDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4659..5885
                     /locus_tag="VXE36_001205"
     CDS             4659..5885
                     /locus_tag="VXE36_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0779517.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     VAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5872..6312
                     /locus_tag="VXE36_001206"
     CDS             5872..6312
                     /locus_tag="VXE36_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0779518.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6366..7778
                     /gene="sufB"
                     /locus_tag="VXE36_001207"
     CDS             6366..7778
                     /gene="sufB"
                     /locus_tag="VXE36_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0779519.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8009..9250)
                     /locus_tag="VXE36_001208"
     CDS             complement(8009..9250)
                     /locus_tag="VXE36_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0779520.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9353..10462
                     /locus_tag="VXE36_001209"
     CDS             9353..10462
                     /locus_tag="VXE36_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0779521.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11108..11455
                     /gene="ssrA"
                     /locus_tag="VXE36_001210"
     tmRNA           11108..11455
                     /gene="ssrA"
                     /locus_tag="VXE36_001210"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11638..11725)
                     /locus_tag="VXE36_001211"
     tRNA            complement(11638..11725)
                     /locus_tag="VXE36_001211"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11689..11691),aa:Ser,seq:gga)
     gene            11887..12627
                     /locus_tag="VXE36_001212"
     CDS             11887..12627
                     /locus_tag="VXE36_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0779522.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12624..13535
                     /gene="pfkB"
                     /locus_tag="VXE36_001213"
     CDS             12624..13535
                     /gene="pfkB"
                     /locus_tag="VXE36_001213"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0779523.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLDIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALFVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13532..15484
                     /locus_tag="VXE36_001214"
     CDS             13532..15484
                     /locus_tag="VXE36_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0779524.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15648..17873
                     /locus_tag="VXE36_001215"
     CDS             15648..17873
                     /locus_tag="VXE36_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0779525.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17918..18346)
                     /locus_tag="VXE36_001216"
     CDS             complement(17918..18346)
                     /locus_tag="VXE36_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779526.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18484..19626
                     /locus_tag="VXE36_001217"
     CDS             18484..19626
                     /locus_tag="VXE36_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0779527.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGI
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19635..20849
                     /gene="thiI"
                     /locus_tag="VXE36_001218"
     CDS             19635..20849
                     /gene="thiI"
                     /locus_tag="VXE36_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0779528.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20984..21808
                     /locus_tag="VXE36_001219"
     CDS             20984..21808
                     /locus_tag="VXE36_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0779529.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            21830..22569
                     /locus_tag="VXE36_001220"
                     /pseudo
     CDS             21830..22569
                     /locus_tag="VXE36_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22582..23748
                     /locus_tag="VXE36_001221"
     CDS             22582..23748
                     /locus_tag="VXE36_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0779530.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            24256..25749
                     /locus_tag="VXE36_001222"
     CDS             24256..25749
                     /locus_tag="VXE36_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0779531.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25762..>26269
                     /locus_tag="VXE36_001223"
     CDS             25762..>26269
                     /locus_tag="VXE36_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0779532.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLL"
BASE COUNT         7820 a         4838 c         5784 g         7827 t
ORIGIN      
        1 cctttgttta ctaaacaagg gatttttctt ttgtctctgc tccttttttg atataatagt
       61 tctatgttaa aatcagaaaa acaatcacgt tatcaaatgt taaatgaaga attgtccttc
      121 ctattggaag gcgaaaccaa tgttttggct aatctttcca acgccagtgc tctcataaaa
      181 tcacgttttc ctaataccgt atttgcaggc ttttatttgt tcgatggaaa ggaattggtt
      241 ttaggcccct tccaaggagg tgtttcctgc atccgtattg cactaggcaa gggtgtttgt
      301 ggtgaggcag ctcactttca ggaaactgtt attgttggag atgtgacgac ctatctcaac
      361 tatatttctt gtgatagtct agctaaaagt gaaattgtgg tgccgatgat gaagaatggt
      421 cagttacttg gagttctgga tctggattct tcagagattg aggattacga tgctatggat
      481 cgagattatt tggaacaatt tgtcgctatt ttgcttgaaa agacagcatg ggactttacg
      541 atgtttgagg aaaaatctta atgtatcaag cactttatcg aaaatataga agtcaaaact
      601 tctcccagtt agttggtcaa gaagttgtgg ctaagactct taaacaagcg gtggagcaag
      661 agaaaataag tcacgcttat cttttttctg gtcctcgtgg aacgggaaaa accagtgttg
      721 ctaaaatctt tgccaaggct atgaactgtc ccaatcaagt gggtggcgaa ccttgcaata
      781 actgctatat ttgtcaagca gtgacggacg gtagtttaga agatgtcatt gaaatggatg
      841 cagcttctaa taatggggta gatgaaattc gcgaaattcg tgataaatct acctatgcgc
      901 ctagccttgc tcgttataag gtttatatca tagatgaggt tcacatgctg tctacagggg
      961 cttttaatgc cctcctaaag acgctggaag aaccaacaca gaatgtagtc tttattttgg
     1021 ccactactga attgcacaag attcctgcta ctattctatc ccgtgtgcaa cgttttgagt
     1081 ttaaatcaat taagacacag gatattaagg aacatattca ctatatctta gaaaaagaaa
     1141 atatcagttc tgaaccagag gctgtggaaa tcattgccag acgggcggaa ggtggaatgc
     1201 gggacgcctt gtctattttg gatcaagccc tgagtttgac acagggaaat gagctgacga
     1261 ctgctatctc tgaagaaatt actggcacca ttagcctatc agccttggat gattatgtgg
     1321 cggccttgtc tcaacaggat gttcccaaag ctttgtcttg cttgaatctt ctttttgaca
     1381 atggtaagag catgactcgt tttgtgaccg atcttttgca ctatttaaga gacttgttaa
     1441 ttgttcaaac agggggagaa aatactcatc atagttcagt ctttgtagaa aatttggcac
     1501 ttcctcaaaa aaatctgttt gaaatgattc gcttagcaac agtgaattta gcagatatta
     1561 agtctagttt gcagcccaag atttatgctg aaatgatgac cgtccgtttg gcggaaatca
     1621 agcccgaacc agctctatca ggagcggttg aaaatgaaat tgctacgctg agacaggaag
     1681 ttgcccgtct caaacaagag ctttctaatg caggtgcggt tcctaaacaa gttgcaccag
     1741 ctcctagtcg accagctacg ggcaaaacag tctatcgtgt cgatcgcaat aaagtgcaat
     1801 ctatcttaca agaggccgtc gaaaatcctg atttagcacg tcaaaatcta attcgtttgc
     1861 agaatgcctg gggagaggta attgaaagtc taggtgggcc ggacaaggct ctgctagttg
     1921 gttctcaacc ggttgctgcc aatgaacacc atgctattct tgcttttgag tctaacttca
     1981 atgctggtca aactatgaaa cgagacaatc tcaataccat gtttggtaat atcctcagtc
     2041 aggcggcagg tttttcacct gagattttag ctatttccat ggaggaatgg aaagaagttc
     2101 gcgcagcctt ttcagccaaa gccaaatctt ctcaaactga aaaagaagta gaagaaagcc
     2161 tgattccaga aggatttgaa tttttggctg ataaagtgaa ggtagaggaa gactaaagaa
     2221 agatttcatg atacaataag tttatgaata aacaacaatt tattattatg gcgctattta
     2281 cagctgctga gacctatttt ttcaatgaag cctggatgac tggccgctat attatggcag
     2341 ccttttgggc aattttactc tttagaaatt tccgagtcag ttatgtgatg ggcaaaatcg
     2401 ttgatgtcat cgatcagcat tttaatagga aagactagcc ctcagcttcc agacaaaatc
     2461 aaagcctttt aggctttttt ttgttatact agaaaagtat atttatagaa tttttgctct
     2521 atttttgggg aaatcagacg tttttctagt aagtactgta aaagttttga aaaagaaagg
     2581 aactatcatg tcagtattag agatcaaaga tcttcatgtt gagattgaag gaaaagaaat
     2641 tttaaaaggg gttaacctga ccctgaaaac aggagaaatt gccgctatca tgggaccaaa
     2701 tggtacaggt aaatcgactc tttctgccgc tatcatggga aatccaaact atgaagtaac
     2761 taaaggtgaa gttttgtttg atggcgtaaa catccttgag ttggaagtgg atgagcgtgc
     2821 gcgtatggga cttttccttg ctatgcaata cccatcagaa atccctggaa ttaccaatgc
     2881 tgagtttctt cgtgccgcta tgaatgcggg taaagaagat gatgagaaga tttcagttcg
     2941 tgagtttatt actaagctag atgaaaaaat ggaattgctc aacatgaaag aagaaatggc
     3001 agagcgttac ctcaacgaag gcttctctgg tggtgagaaa aaacgcaatg aaattcttca
     3061 acttttgatg ttggagccaa catttgctct tttggatgag attgactcag gtcttgatat
     3121 tgacgctctt aaagttgtgt ctaaaggtgt caatgccatg cgtggtgaag gttttggtgc
     3181 tatgatcatt actcactacc aacgtctttt gaactatatc acacctgatg tggtacacgt
     3241 gatgatggaa ggtcgtgttg tcctttctgg tggtccagaa ttggctgcgc gtttggaacg
     3301 tgaaggatac gcaaaactag ctgaagaact tggctacgac tacaaggaag aattgtaatt
     3361 ccctcgtatc ttttaggaga agtaaatgac tagagaaaat attaaacttt tttcagaaat
     3421 gcacgctgaa ccaagctggt tggctgatct ccgtcaaaaa gcttttgaca agattgagac
     3481 tttggaatta ccagttattg agcgtgtcaa attccaccgt tggaatctgg gtgatggaac
     3541 gattacagaa aatgagccat cagcaaatgt tccagatttc acagctttag atcatcactt
     3601 gaagttggtg caagtaggaa ctcaaactgt tttcgaacaa actccagttg agttagctga
     3661 acagggtgtt gtcttcacag actttcactc agctttagaa gaaattccag agctgatcga
     3721 agaattcttc atgtcatctg ttaagtatga tgatgacaag ttggcggctt accacacagc
     3781 ttactttaac agtggtgctg tactctatat tccagataac gtagaaatta cagagccaat
     3841 tgaaggaatt ttctaccaag atagcgatag caatgtgccg tttaacaagc atattatgat
     3901 tatcgctggt aaaaattcta agattagtta tctggagcgt ttagagtcac gcggtgaagg
     3961 aagtgacaaa gcaactgcca atatcacagt ggaagtgatt gcacgttctg gtgcgcaagt
     4021 caagtttgct gctatcgacc gtctaggtga aaacgtcact gcctacatta gccgtcgtgg
     4081 taaattaggc gacgatgcaa gtattgactg ggctatcggt gtcatgaacg aaggaaatgt
     4141 cgttgctgat tttgatagtg acttgattgg taatggtagc catgctgacc tgaaggttgt
     4201 agctctttca agtggtcgtc aggtacaagg gattgatact cgtgtaacta actatggctg
     4261 caactctatc ggaaatatcc tacaacatgg ggttatcctt gaaaaagcaa ctttgacttt
     4321 caatggtatc ggccacatca tcaagggtgc taagggagca gatgcgcaac aagagagccg
     4381 tgttcttatg ctttcagacc aagcgcgttc agatgctaac ccaattcttt tgattgatga
     4441 aaatgacgta actgcaggac atgcagcctc tattggtcag gtagatccag aagacatgta
     4501 ttacctcatg agtcgtggct tggataaggc aactgcagag cgtttggttg ttcgtggttt
     4561 ccttggatct gttatcgtgg agattccagt caaggaagtt cgtgatgaaa tgattgcaac
     4621 tatcgaagag aaattgtcaa aacgctaagg ggaagcctat gttagatgta gaagcgattc
     4681 gcaaggattt tccaatttta gatcagattg tcaatgatga acctctggtc tatctggaca
     4741 atgctgcgac gacacaaaaa ccactagtag ttctgaaagc tattaacagc tactatgagc
     4801 aggacaatgc caatgttcac cgtggtgtcc ataccttagc ggaacgagcg acagcttctt
     4861 atgaagctgc tcgtgaaacc attcgtaagt ttattaatgc aggctctaca aaggaagttc
     4921 tctttaccag aggaacgaca accagcctta actgggtggc acgctttgct gaggaaattc
     4981 tcgctgaggg agaccaggtc ttgatttcag taatggaaca ccattctaat atcattccat
     5041 ggcaggaagc ttgtcgaaag actggagcag agcttgtcta tgtctatctt aaagacggtg
     5101 ccttggatat ggaggatttg cgagctaaat tgactgataa ggttaaattt gtttccctag
     5161 ctcatgcctc caatgttctt ggtgtggtca atccgatcaa ggaaatcact caattagccc
     5221 accaagttgg ggcaattatg gtagtggatg gtgctcaatc tacacctcat atgaagattg
     5281 atgtccagga cttggatctg gactttttcg ccttttcggg tcacaagatg gctggtccga
     5341 ctggtatcgg tgtcctttac ggcaaagaaa agtatcttga gcaaatgtct ccagtagaat
     5401 ttggcggcga gatgattgat tttgtctacg agcaatttgc tagttggaag gaattgcctt
     5461 ggaaatttga ggctggaacg ccaaatgtgg caggagctat tggacttgcg actgcagttg
     5521 attatctgga aaagattggt atggatgccg ttgaagctca tgaacaggaa ttgattgcgt
     5581 acgtctatcc aaaactgcag gcaattgagg gattgaccat ttacggttct caggatttgg
     5641 ctcaacgttc gggtgttatt gcctttaacc taggtgatct ccatcctcac gatcttgcga
     5701 cggctctgga ttatgaagga gtggctgttc gtgctggtca ccattgtgcg caacccttgc
     5761 ttcagtattt ggaagtccca gcaacagctc gtgcaagttt ttatatctac aataccaagg
     5821 cagattgcga caaactagtc gatgccctac aaaagacaaa ggagtttttc aatggcactt
     5881 tctaaactag atagccttta tatggcagtg gtagcagacc attcgaaaaa tccacatcac
     5941 caagggaagt tagaagatgc tgagcaaacc agtctcaaca atccgacttg tggggatgtc
     6001 atcaacctct ctgtcaagtt tgatgcagag gaccgtttgg aagatattgc ttttctaaat
     6061 tcaggatgca cgatttcaac tgcttctgct agtatgatga cagatgccgt tttaggaaaa
     6121 accaaacaag aaattttaga actggcgact attttttctg aaatggttca ggggcaaaaa
     6181 gatgagcgtc aaggccaact tggagacgcg gcattcttgt caggtgttgc caaattccct
     6241 caaagaatca agtgtgcaac cctagcttgg aatgccctta agaaaacaat tgaaaatcaa
     6301 gaaaaacagt aagacaagtt tcttttgtct tatgaattat tagaaatgaa gaaagaaagg
     6361 atactatggc tgaagaaaga gtagaaccaa aaccaattga ccttggtgaa tataaatttg
     6421 gtttccatga cgatgtagag cctgtcttat cgacaggaaa aggactcaac gaaggtgtta
     6481 ttcgtgaatt atctgctgct aagggtgagc ctgagtggat gttggagttc cgtttgaagt
     6541 cttatgaaac cttcaaaaaa atgcccatgc aaacttgggg agcagacttg tcagagattg
     6601 actttgatga cttaatctac taccaaaaac catctgacaa accagcccgt tcttgggatg
     6661 atgtacctga aaagattaaa gaaacctttg aacgtatcgg gattccagaa gctgaacgtg
     6721 cttatttagc aggggcttct gcccagtacg agtcagaagt ggtttaccac aacatgaagg
     6781 aagagttcca aaaattaggt attatcttta cagatacaga ttccgcactc aaggaatacc
     6841 cagacttatt taaacaatac tttgcgaagt tggtaccgcc gacagataac aagttggcag
     6901 ccctcaactc agcagtatgg tcgggtggaa cttttatcta cgtgccaaaa ggtgtcaagg
     6961 tagatattcc acttcaaact tatttccgta tcaataacga aaatataggt cagttcgaac
     7021 gtaccttgat tatcgttgat gagggagcaa gcgtccacta cgtagaagga tgtacagcac
     7081 caacatattc aagcaatagc ttacacgctg ccattgtaga aatttttgct ttggacggag
     7141 cttatatgcg ttatacaact atccaaaact ggtctgataa cgtctataac ttggtaacaa
     7201 agcgtgctaa ggctcaaaag gatgccactg ttgagtggat tgatggaaac ttgggtgcca
     7261 aaacgactat gaaatatcca tctgtttacc ttgatggaga aggagcgcgt ggtaccatgc
     7321 tctctatcgc ctttgctaat gcagggcaac accaagacac gggtgctaag atgattcaca
     7381 atgctccaca taccagctcg tctattgtgt ctaaatccat cgctaaaggt ggaggaaagg
     7441 ttgactaccg tggacaagtc acctttaaca agaactctaa gaaatctgtt tcccacattg
     7501 aatgtgatac cattatcatg gatgacttgt cagcatcaga tactattcca tttaatgaaa
     7561 ttcacaactc gcaagtggct ttggaacacg aagccaaagt atctaagatt tcagaagagc
     7621 aattgtatta tctcatgagc cgtggattgt cagaatctga ggcaactgaa atgattgtca
     7681 tgggatttgt agaacccttt acaaaagaac ttccaatgga atacgcagtt gagctgaacc
     7741 gcttgattag ctatgaaatg gagggatcag ttggataaaa tttgatttta tactcttcga
     7801 aaatctcttc aaaccacgtc agcatcgcct taccgtatgt atggttactg acttcgtcag
     7861 tttcatctac aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttatt
     7921 ctttgatttt gagtattaga tttactcaaa atcaaggatt ttgaagatga acttgtatca
     7981 aaaaatcgcg gtttaaaatc gcgatttttt ataatttctc gttaacaaag cggacaaact
     8041 gattccacca aacttttaag aagaaggctt tttcaatttt cttgtctgct accatttcga
     8101 aactagggcg ctctgtggtg atgtaacctt gaccaatcaa gttcttgtct tcataagtca
     8161 aatggccaac cactgttcca gcttcaagtg gtgctgggat tgctttggaa tcaggtgtga
     8221 attgaacaga ttgggaagat tgattcccaa cacgttctat tagatagata tcctctggag
     8281 ccactgcagt tactgtatct tcttttccat cttgtacagg ggctttgcta tcttgatagg
     8341 catcgccttg ttgaacgatt ttgcgaagtg taaatgtaga agaaatataa tccattaggg
     8401 aagatgtagc tgtaaatcga gcgtaaggat tattgtcttg atgatctgca tttaaaacaa
     8461 ctgtgatgac tctcatgcct ttttcgacag tagtaccaac aaaagactct ccagccttat
     8521 ctgttgttcc tgtttttagc ccatcaaaac caccacggta agcaggcata ccttctaaca
     8581 tgtagttggt tgaagtgatt gtcatcccag caaaagtaga agaaggtttt ttggtgattt
     8641 ctaagacttg tgggtatttt ttgatgaggt tgcgagcaac gatagcgaca tcataagcac
     8701 taagcttatt ttcctcatct tttttagaac ctgggtaaat gttatcccct agagtttcat
     8761 tgttaagacc tgtcgtattg acaacagtgg catcctgaat tccccattcc aagagttttg
     8821 cccgcatcat atcgacgaaa tctttttctg agccagcaat tttctcagct agggcaatag
     8881 cggcgctgtt ggcactagat accagagttg cttcaagcaa ctcttcgaca gtataattac
     8941 gggcctccat aggaatatta ctggcttcag aatttgtcgt caattgataa ggataatcag
     9001 aaatatctac aggagtggag agggtaatac ttccgttttc caaagcttca tagaccagat
     9061 aaacagtaat caattttgtt atggaagcaa tttcgacagg ttgcgttgca tccttctcat
     9121 agagaatttt accagtattt gcctcaacag caatcgcatg tttagcggca atggtaaaat
     9181 cttgagcaac agcagtagaa gcacccccta aaagagagac agttaacaaa gttaaaaata
     9241 tttttttcat agtagtttta ttctatcata aagaaaaaaa atattcttgc tttaataatt
     9301 catctgttaa gctttttgaa aatatggtaa aataaagtga gggaggtaac tcatgtttcg
     9361 tagaaataaa ttattttttt ggaccacaga aattttactc ttaaccatca tcttttacct
     9421 atggagacag atggggtctt tgattaaccc ttttgttagc gtgcttaata caattatgat
     9481 cccattttta ttagggggct ttctttatta tttgacaaac cctattgtta ctttcttaaa
     9541 taaagtctgt aaactcaatc gtttgcttgg tattttaatt accttgtgta ctttggtctg
     9601 gggaatggtc ataggtgttg tctatctctt acctattttg attaatcagt tatctagttt
     9661 gattatatct agtcaaacta tttatagtcg agtacaagac ttaatcatag acttatctaa
     9721 ttatcctgcg ctccagaatt tggatgtaga agctacaatt cagcagttaa acttatccta
     9781 tgttgatatt cttcaaaata tcctaaatag cgtatcaaat agtgtgggga gcgtcttgtc
     9841 agctcttatc agtactgttt tgattttgat tatgactcca gtttttttgg tttatttctt
     9901 attagatgga cataaattct tgcccatgct tgaaagaacg attctaaaga gggatcgctt
     9961 gcatattgca ggcttattaa agaatttaaa tgcgacgatt gctcgctata ttagtggagt
    10021 ttcgattgac gcaatcatta taggttgttt agcttatatt ggctatagta ttattggttt
    10081 aaaatatgct ttagtttttg ccattttttc tggtgtagcc aatttaattc cttatgtggg
    10141 gccaagtatt ggtttgattc ctatgatcat cgcaaatata ttcactgatc cccatagact
    10201 gctgattgca gtgatttata tgcttgttgt tcagcaggta gatggcaata tcttatatcc
    10261 tcgaatcgta ggaagtgtta tgaaggttca tccaatcacg attttagttt tacttttgtt
    10321 gtcaagcaat atctatggtg tagttggaat gattgtcgca gtgccaacct attctatctt
    10381 gaaagaaatt tctaagttct tatcccgttt gtatgaaaat cataaaataa tgaaagaacg
    10441 agaaagagaa ttagctaagt aaaagtcagg agaaccctga tttttcttta ctggaagtgg
    10501 cctttagatt agaagactga aaataagtta aagtcttaaa ctaattttca cagctaagaa
    10561 tagtagaagt taatctgata aaaatcgaaa aaaccagtgg aattccgtgt cagggtaagt
    10621 tccactggtt ttcatagtct attaaagttc gaatgaaacc tatttatagt agattgaaac
    10681 tagaatagta cacctctaat tctaaaacat tgttagaaat cgatttgact gtcctgatct
    10741 attcgtccta ttcttatttc attttactat attttggtgc aataagtgaa aagtagtccg
    10801 aataatataa ggattgattt tatagttttt aaactcaaat gaattaaaat aaagagagta
    10861 cgaaaattct catctgaaag tattttagaa taattctctt cgtgaatttc ttcaaaacag
    10921 atagcttcat cttaggtatg tgttaattgg atttcgtaag ctctatttac aatcgtaaag
    10981 ttatgcactg agaaagttgt agttagtctt ccagtttgct aaatttctcg aatagtatct
    11041 tttttaggta tgtgatttct ttttgcattt ttgagttaga taaggtataa tggttttatt
    11101 gtcttttggg gtcgttacgg attcgacagg cattatgagg catattttgc gactcgtgtg
    11161 gcgacgtaaa cgctcagtta aatataactg caaaaaataa cacttcttac gctctagctg
    11221 cctaaaaacc agcaggcgtg acccgatttg gattgctcgt gttcaatgac aggtcttatt
    11281 attagcgaga tacgattaag ccttgtctag cggtttgata agagattgat agactcgcag
    11341 tttctagact tgagttatgt gtcgaggggc tgttaaaata atacataacc tatggttgta
    11401 gacaaatatg ttggcaggtg tttggacgtg ggttcgactc ccaccggctc cattattcct
    11461 ttgcattctt ttgcattcct tggtaaaacg ttgttaaatc aacgtttttt atttttatct
    11521 ttggtattca tttgcattct tttgctaaaa agggagtcac aaacagaccc tattttaaaa
    11581 aaaggataga aaaaaggata caacatttgt cgcatcctaa aaataatctt ttttcgacgg
    11641 aagacatggg attcgaaccc acgcacgcta ttacacgcct accgcgtttc caacacggcc
    11701 tcttaagcct cttgagtaat cttccaatac ttactcaaat agtctaccat aaaggctctt
    11761 atcttgcaat aaaaattcta gaaataagaa aaatgataga ttttgaaaga aaatgataaa
    11821 aaatgcttga cttcaaaaga aagtatgata gaatgaatag tgtaaacgat aacaggaggt
    11881 gattcggtgt taaaaacaga gcggaagcaa ctgattttag aggagttaaa tcaacatcat
    11941 gtagtttctc tagaaaaatt agttagtttg ctagaaacgt cagaatcaac ggttcgaaga
    12001 gacttggatg agttggaagc ggaaaacaag cttcgtcgtg tgcatggtgg agcagaactc
    12061 ccccactcct tacaggaaga agaaaccatt caagaaaaat ctgtcaaaaa ccttcaagaa
    12121 aagaagttgc tggctcagaa agcagcctct ctcattaaag aaaaagatgt catctttatc
    12181 gatgctggaa caacaactgc ttttttgatt catgaattgg tcaataagaa tattacagtt
    12241 gtgaccaact ccattcacca tgccgctcag ttggttgaaa agcagattcc aactgtcatg
    12301 gttggaggaa acgtcaagac ggcgacagat gctagtatcg gtggcgttgc tcttaaccag
    12361 attaaccaat tgcactttga ccgtgccttt atcggaatga atggtgttga cgatggctat
    12421 tatacgactc ctgatatgga ggagggagct gtgaaaagag ctattttgga gaatgccaag
    12481 cagacctacg tcttggtgga ttcgtcaaaa attggacaaa cttgctttgc caaggtagcc
    12541 ccactcaaac gcgctatcgt tatcactagt caagggcatg agctcttgca ggttattaag
    12601 gagaaaacgg aggtaataga agtatgattt atacagtcac actcaatcca tccattgact
    12661 atatcgttcg tttggaccaa gtcaaagttg gtagtgtaaa tcgtatggac agtgatgata
    12721 agtttgctgg tgggaaagga atcaatgtca gccgtgtctt gaaacgcttg gatattccta
    12781 atacagcgac gggatttatc ggtggcttta ctggtaaatt tatcacagat actctagcag
    12841 aggaagaaat cgagacacgt tttgtccaag tggcagaaga tactcgtatc aatgttaaaa
    12901 tcaaagcaga ccaagaaaca gaaatcaacg gaacgggtcc aactgttgaa ccggttcagc
    12961 tagaagaatt gaaagctatt ttatctagtc tgacagcaga agatacagtt gtctttgcag
    13021 gttcaagtgc taaaaatcta ggcaatgtta tctataagga tttgatttcc ttgacgcgcc
    13081 agactggtgc gcaagtggtc tgtgactttg aaggacagac cttaattgat agtttggact
    13141 accagcctct tcttgtaaaa ccaaacaatc atgaacttgg agcgattttt ggggttaaac
    13201 tcgaaagttt agatgaaatt gagaaatacg ctcgtgagtt actggctaag ggtgctcaaa
    13261 atgttattat ctctatggct ggtgatggtg ccctttttgt cacatctgag ggagcttact
    13321 tcgctaaacc aatcaaagga acagtcaaaa attcagttgg agctggtgat tctatggttg
    13381 ctggattcac aggtgaattt gtcaaatcaa aagacgtagt agaagccttc aaatggggag
    13441 tggcttgcgg aacggcaact accttctcag atgacttggc aacggcggaa tttattaaag
    13501 aaacatatgg aaaagttgag gtagaaaaac gatgaaaatt caagacctat tgagaaaaga
    13561 tgtcatgttg ctagatttgc aggcaactga aaaaacagct gtcatcgacg agatgattaa
    13621 aaatttgaca gaccacggtt atgtaacaga ttttgaaaca tttaaagaag gaattttggc
    13681 gcgtgaagct ttgacttcta ctggtttggg tgatggaatc gcaatgcctc acagcaaaaa
    13741 cgctgctgtc aaagaagcga cagttctatt tgctaagtca aataagggtg ttgactacga
    13801 gagcttggat ggacaagcaa ctgacctctt cttcatgatt gcagctccag aaggtgccaa
    13861 tgatactcac ttggcagcct tggcagaatt gtctcaatac ttgatgaaag acggttttgc
    13921 agacaaactt cgtcaagcaa catctgcaga ccaagttatc gaactttttg accaagcttc
    13981 agaaaaaact gaggaacttg ttcaagcacc tgctaatgac tctggtgact ttatcgtagc
    14041 tgttacagct tgtacaacag gtattgccca cacttacatg gcccaagaag cccttcaaaa
    14101 agtagctgct gaaatggggg ttggtatcaa ggtcgaaacc aacggtgcta gcggtgttgg
    14161 aaatcaacta actgcagaag atatccgtaa ggctaaagct attatcattg cagcagacaa
    14221 ggccgttgaa atggatcgat ttgatggaaa accattgatc aatcgtccag ttgctgacgg
    14281 tatccgtaag acagaagagc taattaactt ggctctttca ggagatactg aagtctaccg
    14341 tgccgctaat ggtgccaaag ctgcaacagc ctctaacgaa aaacaaagcc ttggtggtgc
    14401 cttgtacaaa cacttgatga gtggtgtatc tcaaatgtta ccattcgtta tcggtggtgg
    14461 tatcatgatt gcccttgcct tcttgattga cggtgctttg ggtgttccaa atgaaaacct
    14521 tggcaatctt ggttcttacc atgagttagc ttctatgttc atgaaaattg gtggagctgc
    14581 ctttggtttg atgcttccag tctttgcggg ttatgttgcc tactctattg ctgaaaaacc
    14641 gggtttggta gcaggtttcg tggctggtgc tattgccaaa gaaggttttg cctttggtaa
    14701 aattccttat gccgcaggtg gtgaagcaac ttcaactctt gcaggtgtct catctggttt
    14761 cctaggtgcc cttgttggtg gatttatcgc aggtgccttg gttcttgcca tcaagaaata
    14821 cgttaaagtt cctcgttcac tcgaaggtgc taaatcaatc cttctattgc cacttcttgg
    14881 aacaatcttg acaggatttg ttatgctagc tgtgaatatc ccaatggctg caatcaacac
    14941 tgctatgaat gacttcctag gcggtcttgg aggaggttca gctgtccttc ttggtatcgt
    15001 ccttggtgga atgatggctg ttgacatggg tggaccagtt aataaagcag cttatgtctt
    15061 tggtacaggt acgcttgcag caactgtttc ttcaggtggt tctgtagcca tggcagcagt
    15121 tatggctgga ggaatggtgc caccacttgc aatctttgtc gcaactcttc ttttcaaaga
    15181 taaatttact aaggaagaac gtaactctgg tttgacaaac atcatcatgg gcttgtcatt
    15241 tatcactgag ggagcgattc catttggtgc cgctgaccca gctcgtgcga ttccaagctt
    15301 catccttggt tcagcagtag caggtggact cgttggtctt actggtatca aactcatggc
    15361 gccacacgga ggaatcttcg ttatcgccct tacttcaaat gctctccttt acctcgtttc
    15421 tgtcttggta ggagcaatcg taagtggtgt ggtttatggt tacctacgca aaccacaagc
    15481 ataaaaaata gaaaaatgaa aagattggac cgtttggtgc agtctttttc tcttcccgaa
    15541 atgcctgtga aatatggtat aatagaagaa tggcaaacaa gaatacaagt acaacaagac
    15601 ggagaccgtc taaagcagaa ctggaaagaa aagaagcgat tcaacgaatg ttgatttcgt
    15661 taggaattgc gattttattg attttcgcag ccttcaaatt aggggctgca ggtataaccc
    15721 tttataattt aattcgcttg ctagtgggta gcctagctta tctggcgata ttcggcctat
    15781 taatctatct cttctttttc aagtggatac gaaaacagga aggactctta tctggctttt
    15841 tcaccatatt tgctggctta ctcttgattt ttgaggccta cttggtttgg aaatatggtt
    15901 tggacaagtc cgttctaaaa gggaccatgg ctcaggttgt gacagatctg actggttttc
    15961 gaacgactag ctttgctgga gggggcttga tcggggtcgc tctttatatt ccaacagcct
    16021 ttctcttttc aaatatcgga acttacttta ttggttctat cttgatttta gtgggttctc
    16081 tcctagtcag cccttggtct gtttacgata ttgctgaatt tttcagtaga ggctttgcca
    16141 aatggtggga agggcacgag cgtcgaaaag aggaacgctt tgtcaaacaa gaagaaaaag
    16201 ctcgccaaaa ggctgagaaa gaggctagat tagaacaaga agagactgaa aaagccttac
    16261 tcgatttgcc tcctgttgat atggaaacgg gtgaaattct gacagaggaa gctgttcaaa
    16321 atcttccacc tattccagaa gaaaagtggg tggaaccaga aatcatcctg cctcaagctg
    16381 aacttaaatt ccctgaacag gaagatgact cagatgacca agatgttcag gtcgattttt
    16441 cagccaaaga agcccttgaa tacaaacttc caagcttaca actctttgca ccagataaac
    16501 caaaagatca gtctaaagag aagaaaattg tcagagaaaa tatcaaaatc ttagaagcaa
    16561 cctttgctag ctttggtatt aaggtaacag ttgaacgggc cgaaattggg ccatcagtga
    16621 ccaagtatga agtcaagccg gctgttggtg taagggtcaa ccgcatttcc aatctatcag
    16681 atgacctcgc tctagccttg gctgccaaag atgtccggat tgaagcacca atccctggga
    16741 aatccctaat cggaattgaa gtgcccaact ccgatattgc cactgtatct ttccgagaac
    16801 tatgggaaca atcgcaaacg aaagcagaaa atttcttgga aattccttta gggaaggctg
    16861 ttaatggaac cgcaagagct tttgaccttt ctaaaatgcc ccacttgcta gttgcaggtt
    16921 caacgggttc agggaagtca gtagcagtta acggcattat tgctagcatt ctcatgaagg
    16981 cgagaccaga tcaagttaaa tttatgatgg tcgatcccaa gatggttgag ttatctgttt
    17041 acaatgatat tccccacctc ttgattccag tcgtgaccaa tccacgcaaa gccagcaagg
    17101 ctctgcaaaa ggttgtggat gaaatggaaa accgttatga actctttgcc aaggtgggag
    17161 ttcggaatat tgcaggtttt aatgccaagg tagaagagtt caattcccag tctgagtaca
    17221 agcaaattcc gctaccattc attgtcgtga ttgtggatga gttggctgac ctcatgatgg
    17281 tggccagcaa ggaagtggaa gatgctatca tccgtcttgg gcagaaggcg cgtgctgcag
    17341 gtatccacat gattcttgca actcagcgtc catctgttga tgtcatctct ggtttgatta
    17401 aggccaatgt tccatctcgt gtagcatttg cggtttcatc aggaacagac tcccgtacga
    17461 ttttggatga aaatggagca gaaaaacttc ttggtcgagg agacatgctc tttaaaccga
    17521 ttgatgaaaa tcatccagtt cgtctccaag gctcctttat ctcggatgac gatgttgagc
    17581 gcattgtgaa cttcatcaag actcaggcag atgcagacta cgatgagagt tttgatccag
    17641 gtgaggtttc tgaaaatgaa ggagaatttt cggatggaga tgctggtggt gatccgcttt
    17701 ttgaagaagc taagtctttg gttatcgaaa cacagaaagc cagtgcgtct atgattcagc
    17761 gtcgtttatc agttggattt aaccgtgcga cccgtctcat ggaagaactg gagatagcag
    17821 gtgtcatcgg tccagctgaa ggtaccaaac ctcgaaaagt gttacaacaa taaaaaaata
    17881 gcttctttcc aagtttggag ggaagctatt ttagtggcta ttgattgctt ttattttctg
    17941 aagttggcgc attggactgt ttttcgtttt cagtagcagg tttacttgaa gcaggagtag
    18001 aagagtcctg agttgctgtt ttctgatctt cttttttctc ttccttgacg ctagattttg
    18061 gtgtttcctc ttgctgtgtt ttttcttgac tagtgttagt ctctttagtt ggactggtgt
    18121 tttccttagg ggattccttt tggatttctt tgacaatggt tgtcgtctgg cttgtcgtag
    18181 gttctttttt aatatttttg ttattatcca aggcgttcat aatcgtgata cttgcggtaa
    18241 tcaagccaag gatactagcg attgtagcaa cggttttttg aaagactgta aagccttttt
    18301 tgatgtgttc tgtttttggt tttgaagttc tacgatagtt agacatacat tctctccttt
    18361 gattatgatt tattatactc tgtttcttta aaaaaatctt aaaaaaagag aaatttccct
    18421 ttcttgtcgc aagctccgtt tcatgataca atagaggaag tgattttaga aagcgtgaga
    18481 aacatgattt actttgataa ttcagcgacg accaagcctt atcctgaagc ccttgaaacc
    18541 tatatgcagg tcgcttcaaa aattttagga aacccatcta gtctccatcg tttgggagac
    18601 caagcaacac gaatcttaga tgcttctcgc caacagattg cagatttaat cggtaagaaa
    18661 agcgatgaaa tcttctttac ctcgggtgga acagaagggg ataactggct tatcaagggt
    18721 gtggcctttg aaaaagctca gtttggcaag cacatcattg tttcagccat tgaacatcca
    18781 gcagtcaaag agtcagccct ctggttgaaa agtcaaggat ttgaagtgga ttttgctcca
    18841 gttgataaga aaggcttggt cgatgttgag gcgttagcag gtttgatacg gcatgataca
    18901 atcctcgttt ccatcatggc tgtgaacaat gaaatcggct ctatccaacc tattgaggct
    18961 atttcagaat tcttggcaga caagccgact atttccttcc acgttgatgc ggttcaggcg
    19021 cttgccaaaa ttccgactga aaagtatctg acagaacggg tggattgcgc gactttctct
    19081 agtcacaagt tccacggggt tcgaggtgtt ggctttgtct atatcaaatc tggcaagaag
    19141 attacacctc ttcttacagg tggtggccag gagcgagatt atcgttcgac aactgaaaat
    19201 gtggcaggga ttgcagcgac agccaaggcc ctccgtttgt ctatggaaaa gctagatatc
    19261 tttaggagca agactgggca gatgaaggca gtgattcgcc aagctcttct gaactatccg
    19321 gatatttttg tcttttcaga tgaggaaaac tttgcacctc atattctgac ttttggaatc
    19381 aaaggtgttc gaggtgaagt catcgttcac gcctttgaag actatgatat tttcatctca
    19441 acaacctcag cttgttcatc taaggcagga aaaccagccg gtatcttgat tgccatggga
    19501 gtggacaaag ataaggccaa gtcagctgtg cgtcttagcc tagacttgga aaatgatatg
    19561 agtcaggtcg agcagttttt gaccaagtta aaattgattt acaatcaaac tagaaaagta
    19621 agataggagc attcatgcag tattcagaaa ttatgattcg ctacggagag ttgtcaacca
    19681 agggtaaaaa ccgtatgcgt ttcatcaata aacttcgtaa taatatttcg gacgttttgt
    19741 ctatctatac ccaagttaag gtaacagcag atcgcgaccg tgcccacgct tacctcaatg
    19801 gagctgatta cacagcagtt gcagaatctc tcaaacaagt ttttggaatt caaaactttt
    19861 ctcctgttta taaggttgaa aaatctgtag aagttttgaa gtcttctgtc caagagatta
    19921 tgcgggacat ctacaaggaa ggtatgacct ttaagatttc tagcaagcgt agcgaccaca
    19981 actttgaact tgatagtcgt gaactcaacc aaacacttgg aggggctgta ttcgaagcca
    20041 ttccaaatgt gcaagttcaa atgaaaagtc ctgacatcaa tcttcaggtg gagattcgtg
    20101 aagaagcagc ctatctttct tatgaaacca ttcgtggggc tggtggtttg ccagttggaa
    20161 cttcaggtaa agggatgctc atgttgtcag gagggattga ctcacctgta gcaggttatc
    20221 ttgctcttaa gcgtggggtg gatatcgagg cagttcactt tgctagtcca ccatatacta
    20281 gtcctggtgc cctcaagaaa gcgcaggact tgacccgtaa attgaccaag tttggcggaa
    20341 atatccagtt tatcgaggtg cctttcacag agattcaaga ggaaatcaaa gccaaagcgc
    20401 cagaagctta tttgatgact ctaactcgtc gctttatgat gcggattact gaccgtattc
    20461 gtgaggtacg aaatggtttg gttatcatca atggggaaag tctaggtcaa gtagccagcc
    20521 aaacccttga aagtatgaag gctatcaatg ctgttaccaa cactcccatc attcgtcctg
    20581 tggttaccat ggacaagttg gaaatcattg acatcgccca ggaaatcgat acctttgaca
    20641 tttcaatcca accgtttgaa gactgttgta ccatttttgc accagatcgt ccaaaaacaa
    20701 atcctaaaat taagaatgcg gagcagtacg aagcgcgtat ggatgttgaa ggcttggttg
    20761 agcgagcagt ggctggaatc atgattactg aaatcacacc tcaagccgaa aaagatgaag
    20821 ttgatgactt gattgacaat ctgctctaat tcagaaaatc caaaagaata gtgaaaatca
    20881 gtaaaaaaag ttagtttttt ctctaaaaac aggtaaaaaa ctaacttttt ttatttttat
    20941 gatataatga tataaaattt tgaatataga gagttttctg acaatgaatc aatcctactt
    21001 ttatctaaaa atgaaagaac acaaactcaa ggttccttat acaggtaagg agcgccgtgt
    21061 acgtattctt cttcctaaag attatgagaa agatacagac cgttcctatc ctgttgtata
    21121 ctttcatgac gggcaaaatg tttttaatag caaagagtct ttcattggac attcatggaa
    21181 gattatccca gctatcaaac gaaatccgga tatcagtcgc atgattgtcg ttgctattga
    21241 caatgatggt atggggcgga tgaatgagta tgcggcttgg aagttccaag aatctcctat
    21301 cccagggcag cagtttggtg gtaagggtgt ggagtatgct gagtttgtca tggaggtggt
    21361 caagcctttt atcgatgaga cctatcgtac aaaagcagac tgccagcata cggctatgat
    21421 tggttcctca ctaggaggca atattaccca gtttatcggt ttggaatacc aagaccaaat
    21481 tggttgcttg ggcgtttttt catctgcaaa ctggctccac caagaagcct ttaaccgcta
    21541 tttcgagtgc cagaaactat cgcctgacca gcgcatcttc atctatgtag gaacagaaga
    21601 agcagatgat acagacaaga ccttgatgga tggcaatatc aaacaagcct atatcgactc
    21661 gtcgctttgc tattaccatg atttgatagc agggggagta catctggata atcttgtgct
    21721 aaaagttcag tctggtgcca tccatagtga aatcccttgg tcagaaaatc taccagattg
    21781 tctgagattt tttgcagaaa aatggtaagt taagaaagga aaaaacgaaa tgcatattga
    21841 acatcttagc cactggagtg gtcatcttaa ccgtgaaatg taccttaacc gttatggaca
    21901 tggtgggatt ccagttgtgg tctttgcttc atcaggtggt agtcacaacg aatactatga
    21961 ttttggcatg attgatgcct gtgcttcctt tatcgaggaa ggccttgtcc agttctttac
    22021 cctatctagt ttggatagtg agagctggtt ggctacttgg aaaaatgctc atgaccaagc
    22081 ggaaatgcac cgtgcctacg aacgttatgt gattgaggag gccattcttt tatcaagcac
    22141 aagacaggtt ggtttgatgg catgatgacg acaggttgct ctatgggagc ctatcatgca
    22201 ctcaatttct tcctccagca tccagatgtc tttaccaaag tgattgctct cagtggtgtt
    22261 tacgacgcac gtttctttgt cggtgattac tacaacgatg atgctattta ccaaaactcg
    22321 ccagtagatt atatttggaa ccaaaacgac ggctggttta ttgaccgtta ccgtcaggca
    22381 gagattgtgc tgtgtacggg gcttggagcc tgggaacaag atggtttgcc atccttttac
    22441 aagctcaaag aagcctttga caagaaacaa attccagcct ggtttgctga atggggacat
    22501 gatgtcgccc atgactggga atggtggcgt aaacaaatgc cttatttcct cggtaatctc
    22561 tatttataaa aggagttacc tatgaattac cttgttattt ctccctacta tccacaaaac
    22621 tttcaacagt ttaccatcga actagctaat aaaggcatca cagtcttggg aattggtcaa
    22681 gagtcttacg agcaattgga tgagcccttg cgcaatagct tgaccgagta ttttcgtgtt
    22741 gataatcttg agaacataga tgaagtcaaa cgtgcagttg cttttctctt ttataaacat
    22801 ggtccaattg gccgcatcga gtctcacaat gaatactggc ttgagctaga cgcaacactc
    22861 agagaacaat tcaatgtttt tggtgccaaa ccagaggatc tcaaaaagac gaaatataag
    22921 tctgaaatga agaaactttt caaaaaagca ggtgttcctg tggtacctgg agctgttatc
    22981 aagacggaag cagatgttga tcaagcagtg aaagaaatcg gtcttccaat gattgccaaa
    23041 cctgataatg gagtgggagc agccgcaacc tttaaacttg agacagaaga cgatatcaat
    23101 cacttcaagc aagaatggga ccattcaacc ctttatttct ttgaaaaatt tgtcacttcc
    23161 agcgaaatct gtacctttga cgggctcgtg gacaaggatg gaaagattgt cttctcaaca
    23221 acctttgact acgcctatac accgcttgac ctcatgattt ataagatgga caattcttat
    23281 tatgtgctca aggatatgga tcctaaactg cgcaagtatg gggaagcaat tgtcaaagaa
    23341 tttggtatga aagaacggtt tttccatatt gagttcttcc gtgaggggga cgattatatt
    23401 accatcgagt acaataaccg ccctgcaggt ggttttacca ttgatgttta taactttgct
    23461 cattccttgg acctttatcg tggctatgca gctattgtcg caggagaaga gttcccagcg
    23521 tcagactttg aaactcagta ttgtttggct acttctcgcc gtgcaaatgc tcactatgtt
    23581 tattcagaag aggatttgct tgccaaatat agccagcagt tcaaggttaa aaaagtcatg
    23641 ccagctgcct tcgcggaact tcaaggagat tacctgtata tgctgaccac tccgagtcga
    23701 caagaaatgg agcagatgat tgcagatttc ggacaacgtc aagaataaga actatcggat
    23761 taaggaaatt aactccctta atccttttgt tttgtctgat aaaaaataag agcatcccaa
    23821 caaggtagct atcataaaac ttgttcgata actatttgaa gcaggattag gtggtcagaa
    23881 attaaatttt aatatttcaa ttgagtcata gtattgtgtt tgcgtatcct taaatcagct
    23941 aaaaggatcc atgacgacac ctatacgata tagttttcaa gataccaaac aagtctatta
    24001 atattcaatg aaaatcaaag agcaaactag gaagctagcc gcaggtttct caaaacactg
    24061 ttttgaggtt gtggatagaa ctgacagagt cagtatcata tacctacggc aaggtgaagc
    24121 tgacgtggtt tgaagagatt ttcgaagagt ataaaatatt caggtgacgc atagatatag
    24181 ttaattgaag ctttgtttga aatctgataa aataatgata ttactaagtt ttaaaaacta
    24241 aagaaaaggg aagatatgat tacaggcgaa ttaaaaaata aaatcgatca gctgtgggaa
    24301 attctttgga cagaaggaaa cgcaaatcct ttaacaaata ttgaacagtt gacttatctc
    24361 ttatttatga aagatttgga tagtgtcgag cttggacgtg aaagtgatgc tgaatttcta
    24421 gggattcctt atgagggagt ttttccaaaa gataaacctg aataccgttg gtcaactttt
    24481 aaaaatatag gagatgctca ggaagtttat cgtttaatga ctcaggagat ttttccgttt
    24541 attaaaaatc tcaaggggga tacagatgat acagcctttt cacgatatat gcgagaagct
    24601 atttttcaaa taaataaacc tgctacgctt caaaaggcaa tttctatctt agatgttttt
    24661 ccaactaggg gattagatgt agattttgat aatgacaaac aaagtattac tgatatcgga
    24721 gatatctatg aatatctgtt atcaaaattg tcgaccgcag gtaaaaatgg acagttccgt
    24781 acacctcgtc acatcatcga tatgatggtt gagttgatgc aaccgactat caaagatatc
    24841 atctcagatc ccgctatggg ttctgctggc ttcttagtat ctgctagccg ttacttaaag
    24901 cgtaagaaag atgaatggga aaccaataca gataatatca atcattttca taatcagatg
    24961 tttcatggaa atgatacgga tacgactatg ttgagacttg gggcgatgaa catgatgcta
    25021 catggagtag aaaatccaca aatcagttac cttgactcgc tgtctcaaga taatgaagaa
    25081 gccgataaat atactttggt tttagcaaat cctcctttta agggctcact tgactacaat
    25141 tcaacctcta atgaccttct tgcaaccgta aaaaccaaaa aaacagaatt actctttctt
    25201 tctcttttct tgcgaacttt aaaaccaggt ggacgagcag cagttatcgt acctgatggt
    25261 gtcctttttg gttcgtctaa agctcataaa ggaattcgtc aggaaattgt agagaatcat
    25321 aagcttgatg ctgtaatctc aatgcctagt ggtgtgttca agccttatgc tggagtttca
    25381 actgccattc tcatctttac aaaaactggt aatggtggta ctgacaaagt ctggttttac
    25441 gatatgaaag cggatggttt aagtttggat gataagcgac aaccgattag cgacaatgat
    25501 attccagata ttatcgaacg ctttcatcat cttgaaaaag aagcagaacg tcagagaacg
    25561 gatcaatctt tctttgttcc agttgctgag ataaaggaaa atgattatga tttgtctatc
    25621 aataaatata aagagattga gtatgaaaaa gttgagtatg aaccaacaga ggtcatctta
    25681 aagaaaatca atgatttaga aaaagaaatt caagctggct tggctgaatt agaaaaatta
    25741 ctcaagtaga gaggtggctg tatgaaaaaa gtgaagttgg gggaagtctt atctctaaaa
    25801 aaaggcaaga aagccactgt acttgctgaa caaacaactc taagccaacg ttatattcaa
    25861 atagatgatt taagaaataa taataattta aaattcactg aaagtttaaa tatgactgaa
    25921 gcactcccag atgatattct gatagcatgg gatggagcta atgcaggaac agttggttat
    25981 ggattatcgg gagctgttgg tagtacaatt acggtcttaa aaaagaatga gcgatacaaa
    26041 gaaaaaatta tatcagatta cttgggagtc tttttggaaa gtaaatcgca gtatttacga
    26101 gaacattcaa caggtgcaac aattcctcat ttaaacaaga atatattact tgatttacaa
    26161 ttagaattgc taggtatcga agaacaagag aacattatct gtattcttaa tacgattaaa
    26221 aggcttatta ctaaaagaaa attgcagtta gatgaactaa acttgctcg
//
LOCUS       DAVLHB010000026        26244 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLHB010000026 DAVLHB010000000
VERSION     DAVLHB010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26244
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.026"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            290..1762
                     /locus_tag="VXE36_001224"
     CDS             290..1762
                     /locus_tag="VXE36_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0779533.1"
                     /translation="MRDLLSKKSHRQLELLFEHKRWFHRSELAELLNCTERAVKDDLS
                     HVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAES
                     ICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYY
                     FLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDK
                     DSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMK
                     CVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILF
                     DQKGNTIRNFQNIFPKFVSDIKKEISHYLETLEVCSSSMMVNHLSYTFITHTKHLVIN
                     LLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDI
                     IISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2124..3125
                     /locus_tag="VXE36_001225"
     CDS             2124..3125
                     /locus_tag="VXE36_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0779534.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3275..4192
                     /locus_tag="VXE36_001226"
     CDS             3275..4192
                     /locus_tag="VXE36_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0779535.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4203..5093
                     /locus_tag="VXE36_001227"
     CDS             4203..5093
                     /locus_tag="VXE36_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0779536.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5122..6738
                     /locus_tag="VXE36_001228"
     CDS             5122..6738
                     /locus_tag="VXE36_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0779537.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSSQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6748..8067
                     /locus_tag="VXE36_001229"
     CDS             6748..8067
                     /locus_tag="VXE36_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0779538.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLKFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8275..8347)
                     /locus_tag="VXE36_001230"
     tRNA            complement(8275..8347)
                     /locus_tag="VXE36_001230"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8312..8314),aa:Lys,seq:ctt)
     gene            complement(8612..9883)
                     /locus_tag="VXE36_001231"
     CDS             complement(8612..9883)
                     /locus_tag="VXE36_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0779539.1"
                     /translation="MPDNLALRMRPKTIDQVIGQDHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFNFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10153..10392
                     /locus_tag="VXE36_001232"
     CDS             10153..10392
                     /locus_tag="VXE36_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779540.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            10557..10736
                     /locus_tag="VXE36_001233"
     CDS             10557..10736
                     /locus_tag="VXE36_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779541.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10873..11052
                     /locus_tag="VXE36_001234"
     CDS             10873..11052
                     /locus_tag="VXE36_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0779542.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            11089..11541
                     /locus_tag="VXE36_001235"
     CDS             11089..11541
                     /locus_tag="VXE36_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0779543.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11832..12302
                     /locus_tag="VXE36_001236"
     CDS             11832..12302
                     /locus_tag="VXE36_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0779544.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLEDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPKY"
     gene            12321..13388
                     /locus_tag="VXE36_001237"
     CDS             12321..13388
                     /locus_tag="VXE36_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEV0779545.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYQLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVGITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKELAEGV"
     gene            13390..13548
                     /locus_tag="VXE36_001238"
     CDS             13390..13548
                     /locus_tag="VXE36_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV0779546.1"
                     /translation="MEIEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            13658..14692
                     /locus_tag="VXE36_001239"
     CDS             13658..14692
                     /locus_tag="VXE36_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0779547.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGVSK
                     SSVSRELSED"
     gene            14754..16937
                     /locus_tag="VXE36_001240"
     CDS             14754..16937
                     /locus_tag="VXE36_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV0779548.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDSPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            16988..18007
                     /locus_tag="VXE36_001241"
     CDS             16988..18007
                     /locus_tag="VXE36_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0779549.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEIVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            18020..18970
                     /locus_tag="VXE36_001242"
     CDS             18020..18970
                     /locus_tag="VXE36_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0779550.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVVAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18972..19715
                     /locus_tag="VXE36_001243"
     CDS             18972..19715
                     /locus_tag="VXE36_001243"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0779551.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19726..21522
                     /gene="pepF"
                     /locus_tag="VXE36_001244"
     CDS             19726..21522
                     /gene="pepF"
                     /locus_tag="VXE36_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0779552.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            21769..22560
                     /locus_tag="VXE36_001245"
     CDS             21769..22560
                     /locus_tag="VXE36_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0779553.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            22671..23339
                     /locus_tag="VXE36_001246"
     CDS             22671..23339
                     /locus_tag="VXE36_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0779554.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(23733..23822)
                     /locus_tag="VXE36_001247"
                     /pseudo
     CDS             complement(23733..23822)
                     /locus_tag="VXE36_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(23819..24352)
                     /gene="queF"
                     /locus_tag="VXE36_001248"
     CDS             complement(23819..24352)
                     /gene="queF"
                     /locus_tag="VXE36_001248"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0779555.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQYYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(24658..24972)
                     /gene="trxA"
                     /locus_tag="VXE36_001249"
     CDS             complement(24658..24972)
                     /gene="trxA"
                     /locus_tag="VXE36_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0779556.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(24989..25210)
                     /locus_tag="VXE36_001250"
     CDS             complement(24989..25210)
                     /locus_tag="VXE36_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0779557.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(25309..25689)
                     /locus_tag="VXE36_001251"
     CDS             complement(25309..25689)
                     /locus_tag="VXE36_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0779558.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            25958..26101
                     /locus_tag="VXE36_001252"
     CDS             25958..26101
                     /locus_tag="VXE36_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV0779559.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KNT"
     gene            26068..>26244
                     /locus_tag="VXE36_001253"
     CDS             26068..>26244
                     /locus_tag="VXE36_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0779560.1"
                     /translation="MGKERREQEHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALK"
BASE COUNT         8259 a         4391 c         5504 g         8090 t
ORIGIN      
        1 caattatttc gattgttatt attatataat tttaaaaaat caaattcttt aattgttgct
       61 attatataat ttttaaaatt aaaaatataa tctttagact tgaatttgat tctgtattca
      121 cgccctcaat agacggtaaa ataagaaaat tgtttatata ttgtctccgt agtgttatta
      181 tacgaaataa aagattttag gaaaagtcgt tatatcatgc tatacctatt ctttgtggta
      241 taattgcaag aggtttaatc cgataattta taaagagaga aagatattca tgagagattt
      301 attatctaaa aaaagtcata ggcaattaga attattattt gaacataaac gttggtttca
      361 tcgttctgaa ctagcagagt tattaaattg tacagaacgt gcagtcaaag atgatctatc
      421 ccatgttaaa tctgcttttc ctgacttgat ttttcattct tctactaatg gtatacgcat
      481 tattaatacc gatgatagtg atattgaaat ggtttaccat catttcttta aacattcaac
      541 tcatttttcg attttagaat tcatcttctt taatgaaggt tgtcaagctg agagtatttg
      601 taaagaattt tatatcagtt catcttcgct ctatcgtatt attagccaaa tcaataaagt
      661 gattaaaagg caatttcaat ttgaagtcag tctgacccct gttcaaatca ttggaaatga
      721 gagagacatt cgttactttt ttgcacaata tttttcagaa aaatattatt tcctagaatg
      781 gccatttgaa aatttttcat cagagccact atctcaattg ttagaattgg tttataagga
      841 aacaagcttt ccaatgaatt tgtcaacgca tagaatgcta aagttgctcc tagttacgaa
      901 cctatataga ataaagtttg gtcattttat ggaagtagat aaagattctt ttaacgacca
      961 aagtttggat tttttaatgc aggcagaagg aatagaaggt gttgctcaga gttttgaatc
     1021 agaatacaat atctctttag atgaagaagt tgtttgccaa ttatttgtgt cttactttca
     1081 aaaaatgttt ttcatagatg aaagtctctt tatgaaatgc gtaaaaaagg atagttatgt
     1141 tgaaaaatct taccatctat tgagtgattt tattgatcag atttcagtca agtatcagat
     1201 tgaaatggag aataaggata atctgatttg gcatctgcat aataccgcac atctgtatcg
     1261 tcaagagttg tttactgagt ttattttatt tgatcaaaaa gggaatacaa tcaggaactt
     1321 tcaaaatatt tttccaaaat ttgtttcaga tataaaaaaa gagatttctc actatttaga
     1381 gactcttgag gtttgttcta gttcaatgat ggtaaatcat ctatcttata ccttcatcac
     1441 tcataccaaa catttggtga ttaatttgct acaaaatcag cctaaactaa aggttttggt
     1501 tatgagtaat tttgatcagt atcatgcaaa attcgttgca gagacacttt cttattactg
     1561 tagcaataat tttgaactgg aagtttggac cgaattagaa ttatcaaagg aatctttaga
     1621 agattcacct tatgatatca ttatttccaa ttttattatt cctcctattg aaaataagag
     1681 actcatctat tcaaataata taaacacggt ctcactcata tatttgttaa atgccatgat
     1741 gtttattcga ttagatgagt aaccaaaaat aacaaaaaaa cgctatttcg cgtttgaact
     1801 gtacctcaaa agttagacag aaaaaatcta atttttgggg tgtttttgtt aagaaaagac
     1861 cttcaatcat ttaagcaaaa tgtacatcta gatttatagc catctaaaac tcttgctttt
     1921 tttatagaag atacgaaaaa agccatgaaa ccaaggcttt tcctgtttta tgtagatgtt
     1981 tacacatgaa aattgaagta ttttcaaaag ctaattggag tgattttatt catgatggga
     2041 taaatgatct ggccaaaaat gattgagaaa tagttgctta aaaagcattt gcatgatact
     2101 atatattgaa aggaggtgat aatatggtag aacaaagaaa atcaattacc atgaaagatg
     2161 ttgctttaga agcaggagtt agtgttggaa ctgtttcacg tgtaattaat aaagaaaaag
     2221 gcattaaaga agtaactttg aaaaaagtgg aacaagcgat taaaactttg aattacattc
     2281 cagattacta cgctagagga atgaaaaaaa atcgaacaga aacgattgca atcattgtac
     2341 caagtatctg gcatcccttc ttttcagaat ttgctatgca tgtggaaaat gaagtctata
     2401 agagaaataa caaattactc ttatgttcta tcaatggtac aaatagagag caagactatc
     2461 tggagatgtt gcgtcataat aaagttgatg gagtggttgc cattacctat agtccaattg
     2521 aacattactt gacgtcagga attccctttg ttagtattga ccgcacatac tcagatattg
     2581 ccattccttg tgtttcatca gataatgatg caggtggaag agaagcagct aaacaattaa
     2641 ttagtaaagg atgtcagcat ttagcctttg tgggcggaca taatacaacc attaatgaaa
     2701 ccaaacgtcg tagaatttca tttgaaaagt atgtccaaga gcataaaata cctcttagta
     2761 tttttgattt ggatgagaca gttactgact attatggaaa gctagagagt ttcttggaag
     2821 aaaattcttc tatagatgga atttttacaa tcaacgattt tacagctttg gatgtgattg
     2881 aaatactaga aaaaaatggc aaacgtattc ctcatgatgt ccaaattatt ggatacgatg
     2941 gaattaaaat ggctggagat agagattatc tactttcaac tattgaacaa ccattggaag
     3001 aaatggcaaa agaagcggtt cgtattttgt ttgatataat tgatggaaag actgttaatt
     3061 tgcagacaat cctaccagta aaatttgttg aaggaaaaac aacaaaaaat gaaaataagt
     3121 cttgacagaa agcgctatca atgatagaat gaattcagat aaaaagattt atttttaaaa
     3181 caaaaatgaa acgtttcaaa aaagaaataa agagacagcg ccaagcgcta tcttttctag
     3241 aaaaaaatga aacgtttcaa aaaaggaggt tgctatgaat agcaaagcga agcaagtttc
     3301 tctttgggaa agaatcaaga aacaaaaact cttgttattg atgactgtcc ccggtttagt
     3361 tttaaccttt atctttaaat acatccctat gtatggggtt ttaatcgcat ttaaagatta
     3421 caatccttta aaaggaattt tagggagtga ttggattggt ttttctgagt ttacaaaatt
     3481 catatcctct cccaactttg gtatcttgtt agccaacaca ttaaaattaa gtatctatgg
     3541 tttattgctt ggctttttac caccaatcat tcttgctatt atgctcaatc aactcttgag
     3601 tgaaaaagtc aaaaaacgaa ttcagctcat tttatacgca ccaaacttta tctcagtcgt
     3661 tgttattgtc ggtatgattt tcctcttctt ttcagtggga ggaccaatca acaattttct
     3721 ttctatgttt ggaatgaagg ctgacttctt gacaaatcca gacttcttta gacctttata
     3781 catctttagt ggtatctggc aaggaatggg ctgggcttca acgctctaca cggcaacatt
     3841 ggtaaatgta gatccagcct tagtagaagc agctcgactg gatggagcca atatcttcca
     3901 acgaatctgg cacattgata ttccagctct taagcctatt atggttatcc aatttgtttt
     3961 agctgcaggt ggaattatga atgtcggata tgaaaaagca ttcttgatgc agacatcgtt
     4021 aaatttgcca acttctgaaa ttatctcgac atatgtctat aaagttggtc ttgtatcagg
     4081 agactattct tactcaacag cggttggttt gtttaatgca gtgattaacg tagtattgct
     4141 tgttgcagtt aaccaaatcg ttaaacgcat gaataatggt gaaggaattt aaggaggaaa
     4201 gtatgaaaaa ttcgattatg gatacaaaat ttgatagacg tatcttactc ttaaataaaa
     4261 tcattattgt ctttatcgtt ttgatgactt tgcttccttt actttatatc gtcgtagcat
     4321 cctttatgga tcctaaggtt ctggttagta gagggattag ctttaatcca gccgattgga
     4381 ctgtagaagg ttaccagcgt gtattcagtg accaatctat tctaagaggt tttatcaatt
     4441 ctctactata ctcttttgga tttgcagctt taacagtatt gttatctgtg tttacagctt
     4501 atcctctttc taagaaagac ttggttggac gtcgttggat taactacttc ttgattgtga
     4561 ctatgttctt tggtggtggt ttagtcccaa cttacttgct cgtaaaagaa ttgggaatgc
     4621 tcaatactcc atgggctatc attgttccag gtgctgttaa cgtttggaat attattcttg
     4681 ctagggccta tttccaagga ttgcctgaag aattagttga agctgctgtc attgatggtg
     4741 caaatgattt acagattttc ttcaaaatca tgcttcctct tgcaaaacca attatgtttg
     4801 ttctcttcct ttatgctttt gtaggacagt ggaactcata ctttgatgca atgatttata
     4861 tcaaggatcc aaacttggaa ccattgcaac ttgtacttcg taaaattctc attcagagcc
     4921 aaccaggtca agacatgatt ggagcacaag cggctatgaa tgaaatgaaa cgtttagctg
     4981 aattgattaa atacgcaact attgtcattt ccagcttgcc attgattgtt atgtatccat
     5041 tcttccaaaa atactttgat aaaggaatta tggctggttc acttaaagga taaaaaaaga
     5101 aaaaataaaa ggagttttct catgaaattc aaaacattct caaaatcagc agttttgttg
     5161 acagctagtt tagcagtact tgcagcctgt ggctcaaaaa atacagcttc aagtccagat
     5221 tataagttgg aaggtgtaac attcccgctt caagaaaaga aaacattgaa gtttatgaca
     5281 gccagttcac cgttatctcc taaagaccca aatgaaaagt taattttgca acgtttggag
     5341 aaggaaactg gcgttcatat tgactggacc aactaccaat ccgactttgc agaaaaacgt
     5401 aacttggata tttctagtgg tgatttacca gatgctatcc acaacgacgg agcttcagat
     5461 gtggacttga tgaactgggc taaaaaaggt gttattattc cagttgaaga tttgattgat
     5521 aaatacatgc caaatcttaa gaaaattttg gatgagaaac cagagtacaa ggccttgatg
     5581 acagcacctg atgggcacat ttactcattc ccatggattg aagagcttgg agatggtaaa
     5641 gagtctattc acagcgtcaa cgatatggct tggattaaca aagattggct taagaaactt
     5701 ggtcttgaaa tgccaaaaac tactgatgat ttgattaaag tcctagaagc tttcaaaaac
     5761 ggggatccaa atggaaatgg agaggctgat gaaattccat tttcatttat tagtggtaac
     5821 ggaaacgaag attttaaatt cctatttgct gcatttggta taggggataa cgatgatcat
     5881 ttagtagtag gaaatgatgg caaagttgat ttcacagcag ataacgataa ctataaagaa
     5941 ggtgtcaaat ttatccgtca attgcaagaa aaaggcttga ttgataaaga agctttcgaa
     6001 catgattgga atagttacat tgctaaaggt catgatcaga aatttggtgt ttactttaca
     6061 tgggataaga ataatgttac tggaagtaac gaaagttatg atgttttacc agtacttgct
     6121 ggaccaagta gtcaaaaaca cgtagctcgt acaaacggta tgggatttgc acgtgacaag
     6181 atggttatta ccagtgtaaa caaaaaccta gaattgacag ctaaatggat tgatgcacaa
     6241 tacgctccac tccaatctgt gcaaaataac tggggaactt acggagatga caaacaacaa
     6301 aacatctttg aattggatca agcgtcaaat agtctaaaac acttaccact aaacggaact
     6361 gcaccagcag aacttcgtca aaagactgaa gtaggaggac cactagctat cctagattca
     6421 tactatggta aagtaacaac catgcctgat gatgccaaat ggcgtttgga tcttatcaaa
     6481 gaatattatg ttccttacat gagcaatgac aataactatc caagagtctt tatgacacag
     6541 gaagatttgg acaagattgc ccatatcgaa gcagatatga atgactatat ctaccgtaaa
     6601 cgtgctgaat ggattgtaaa tggcaatatt gatactgagt gggatgatta caagaaagaa
     6661 cttgaaaaat acggactttc tgattacctc gctattaaac aaaaatacta cgaccaatac
     6721 caagcaaaca aaaactagag gttgattatg ggagataaga aatacacagt agaaaaagcc
     6781 aatcgtttta tagcagaaaa taaacatctc gttaatactc aatataagcc tgaagaacat
     6841 ttttcagctg agattggttg gatcaatgat ccaaatggat ttgtttattt tcgtggagaa
     6901 taccatctct tttatcaatt ctatccatat gatagtgttt ggggacctat gcactgggga
     6961 catgctaaaa gtaaggactt ggtgacttgg gagcacttgc cagtggcact tgctcctgac
     7021 caagattatg accgaaatgg ttgtttctca ggctctgcca ttgtcaagga tgatcgcctc
     7081 tggctcatgt acactgggca tatcgaagaa aaaaccggtg tccgccaagt gcaaaatatg
     7141 gcattttcag atgacgggat tcactttgaa aagatttccc aaaatccagt tgcaacagga
     7201 gcagacttgc cagatgagtt gattgctgct gatttccgtg atccaaaact ctttgaaaaa
     7261 gatggacgct attactccgt agtagctgcc aaacacaagg ataatgtggg ctgtatcgtt
     7321 ctactagggt ccgataacct agtagaatgg cagttcgaat ccatcttttt aaaaggggga
     7381 gaacaccaag gctttatgtg ggaatgccca gattacttcg agttagatgg gaaagattgc
     7441 cttattatgt cacccatgcg ttatcagcgt gagggagact catatcataa catcaactca
     7501 tcgcttttgt tcacgggtaa ggtagattgg ggagaaaaac gttttatccc agaatcagtt
     7561 caagaaattg atcatggcca agacttctat gcgcctcaaa cattgttgga cgatcaaaat
     7621 cgtcgtattc tgattgcttg gatgcagaca tgggggcgta cccttccaac ccatgaccaa
     7681 gaacacaagt gggcatgtgc catgacttta cctagaattc taagattgga agatggcaaa
     7741 ctaagacaat tccctgttaa aaaaggccaa tatcaaatcc aaatagataa agattgtcat
     7801 taccacttag gaaatgatac agattatctt aaatttggtt atgacagtaa tgcgcagcaa
     7861 gtttacattg atcgtagcca tcttattcaa aaaattctag gtgaagaaga acaggacact
     7921 agtcgacggt atgtagatat tgaagctaaa gaattggaag ttgttctaga taaaaattcc
     7981 atcgagattt ttgtcaatca aggtgaagca agcttgactg caacttatta cttaacggtg
     8041 ccagctgagc tatcacgaat tgattaaaaa ttaagttatt tctcctaaag aaaaagttct
     8101 ctttctaaaa tagtggaaag aggacttttt gtgttttggg tatataagct tagtttatgg
     8161 tatttgtaaa attggtgttg gattatgatt taagctagtt ttctaaagaa tttgaaaaaa
     8221 attttattta agcaaaaaaa ccttggttcc aaggcttttc ctgttgtatt tagatgcccc
     8281 ctacagggat cgaacctgtg acccacggat taagagtccg ctgctctgcc agctgagcta
     8341 aggaggcaaa gaaaaaagct gtattggtgc cgaaacttca cggtttgtat tgaacccgcg
     8401 caattaagca ggtgggcaac tcgctctaac tgaagctgtt tccgtgtgag acggcctaca
     8461 tgctgttaga agacttttgt ttccctaata atacaaaaaa tagtcggtca acacttaagt
     8521 gtgaagtcgt acaccacagc gtttctatac ttatatgata ccactttttc aaaaaaaatc
     8581 aagaggaaag tgcaattttt tgaaaaggat ttcagatttt tcgcaaacgg tcgatagctt
     8641 cctttctttg agccaaagcc cgttcatatt taccagtatc ttctgcttgg aaatagtgat
     8701 gattacgaat tttttctggc agatagtctt gcttgaccca atttccagga tagttgtgtg
     8761 gatagagata gtcttgggca ttccccagtt ccttgcttcc actgtagtgc ccatcacgta
     8821 ggtgtcgcgg aataggcaag tgccctgatg ttttgaggtc agcaagtgcc ttatccatag
     8881 ctacataggc tgagttggat tttggagaaa gggccaaatc aatcacgaca ttggcaatga
     8941 gaatgcgggc ttctgggaac ccaatcttct gggcagcatc cagagcagtc acggtatgaa
     9001 tctgggcctc aggattggct aagccgatat cttcataggc gataacagtc aagcgacgag
     9061 cgagactagg cagatcccca gcctcaatca agcgggcagc atagtggaga ctggcatcca
     9121 catctgagcc acggatagac ttttgcaggg cagatagaac atcatagtga ccgtctccat
     9181 ccttgtccat agtgatgtag cttctctgaa gactattttc catgatgtct aaggtgatgt
     9241 ggcgaatgcc ctcgtcattc tcaggggtag agagaacagc caagtccagt gagttaaagg
     9301 cagagcgaag gtctccgttt gtagaggttg cgatgaaatc cagcgcatcc tcatctagtt
     9361 ctattggaaa attaaaacca cgttcagggt tacttagagc tatctgcagg gcctctttga
     9421 cgtcttggtt agacagaggt tccaactcaa aaatttgaac acggctacga atggcaggag
     9481 tgacggaaaa gaaaggattt tcagtcgttg ctccaatcat gatgaccagt ccactttcca
     9541 agagaggcaa gaggaagtct tgcttggtct tatctagtcg atgaatttcg tctagcaata
     9601 ggacgagacc accagaaaat ttagcttctt ccgagatttc ttgcagtcgc tttttactat
     9661 caactgtcgc attgaaagtt cgaaaggcat acttggtcgt tccagcgatg gcagaggcaa
     9721 tactggtttt gccgattcca ggagggccat atagaatcat ggaggacagg cggttggctt
     9781 ccaccatgcg gcggatgatt tttccaggtc cgaccagatg atcctgaccg atgacctggt
     9841 cgatggtttt agggcgcatg cgaagcgcga gattgtctgg catagcagtc ctttctagcg
     9901 tggatttgag tagaatgact catctactat atcttactat gtccattcta gcctattagt
     9961 tgtgatattt caatggtttt gtaataatca gggagtgaga tagaatcttt tttactattt
    10021 aatttaatga ggagaggtat cagcatgaga gatttgattt tccttaaagc tcaaaatagg
    10081 atagttgagc ctaaagaagt ggaagtgctg acttgagaaa taatattgct gaatgtcatt
    10141 gtatgaacta taatgaaaag agaggtgata agcaatggaa atgatggacc aagtcaggaa
    10201 attttgattt ttacaaaaca aattcgtcat tggattctta gtgatcaagt tatttcaggg
    10261 aaaagaaaac ttttcttccg ggaagatact ccaaaagaga ttttagattt gtacgaaaac
    10321 attaaatcta aacttgattt tgcttaccaa gaagtttatt ctaataatgg attgaaaaaa
    10381 tatgaaaaat agaataattg atgtttttga agtagtaaat cgcctccttg taataactgt
    10441 tgaaaatcct gatttcgaag acttgagagt taatcatact caatgaaaat caaagagcaa
    10501 actaggaaac tagccgcagg ctgtacttga gtacggtaag gcgacgttga cgtggtttga
    10561 atttgatttt cgaagagtat cagtttgtaa aaattggaga taaaaaatat agagtacgca
    10621 gtggtcctat gattcattca actccgcctc aatctgtctt agatcgagat acttttacaa
    10681 ttgactatac agatgatgaa ttgctcgata aagaagcagt ttttactact cattagaaaa
    10741 ataggtctga ataaattggt ttcccttaga accacatcta ggggctttta tgtataatag
    10801 aataataagt atcactcctt tacaatacgt gtaacacgtg ttataatggt gttgtcagga
    10861 ggtaaaagcg ctatgcctat gacacaaaaa gagatggtta aactctttac ggcccatggt
    10921 tggataaaga ctagaggcgg taaaggctcc catattaaaa tcgagaagca aggggaaaga
    10981 cctatcacaa tccttcatgg tgagctgaat aagtacactg aaagagggat aggaaagcaa
    11041 gctgggttgt aaaattcagt ccctgctttt tgatatggag gtagtgaaat gttagttacg
    11101 tatccagctt tattttatta tgacgacaca gacggaacag aagcgactta ttttgtccat
    11161 ttcccagatt ttgaatactc agctacacaa ggagagggga tttctgaggc tttggctatg
    11221 gggtcggagt ggctagggat aactgttgca gatttgatag agagtgatgg agagttacct
    11281 cagccatcag atatcaatag cttgtcttta attgataatg atccttttaa agatgatgaa
    11341 gatttcgtgt caacctatga ccttgataaa tcttttattt ctatggtatc tgttgatgta
    11401 tcagaatacc taggaagtca ggaacccatt aaaaagactt tgaccatacc aaaatgggca
    11461 gataagttgg gacgagaaat gggacttaac ttttctcaga ctttgacaga cgctattgca
    11521 gataagaaag ttcaagccta agattaagcg tggtaccgtg gtaatagtca ataaaaaagc
    11581 acgtccactt gtgctagtta ctcgcctatt gattttatag atttattagc cctttcgagg
    11641 gctttttata ttgattttta tgagaaatga agaaatcaga cttttaagaa aatcactgat
    11701 accaagggtt taaatgaggt aatatggtat aattaggaca taaaataatt ttgtggtaag
    11761 atggtagtat ctattttagc atatttccga gcaatcgggg cgattaaaga gtcgcataga
    11821 aagaggacaa aatggcaaca tacggatttt tagatatttt agaggaagag ttggacaaga
    11881 actttccctt tgactttgag attagttggg acaagcgtaa ccacgcggta gaagtgagtt
    11941 ttctattgga agcgcaaaat gctgcaggtg tggagatggt ggatgaagac ggagaggttt
    12001 catcagatga cattcttttt gaggaagcgg tccttttcta caatcctgcc aagtcaaccg
    12061 tcaatgcaga agactattta acggttatcc cttatctacc taaaaaagga ttttctcgcg
    12121 agtttttagc ttattttgcc cttttcctcg aagatactgc ggaggttggg ctagataccc
    12181 tcatggactt tttggaagat ccagaagcag aggaatttgt tatggaatgg aatcaagaag
    12241 tctttgaaga aggaaaagtt ggcttggaag agggagaatt ttacccttat ccaaaatact
    12301 aggagttggt tggaggtgtt atgaagaaaa ttgggactta tttggtttat gtgctagctg
    12361 ttgtctttat tatgctagct tttgcttgtg gaacaatcgc atttgcagag ttggggtatt
    12421 ccgcagtttt agcctttact tttggttatg ccttcgctct tctaagcatg tatttaatct
    12481 ttattcttca tgagctgggt catgcttttt gtggctactt gacaggctat cagctggtgg
    12541 cttttggatt aggacatttt attttgacaa aaaagtcagg caggtttcat cttagtagaa
    12601 cagccattct gaaaaatgtt ggtgctcaat acattggttt aaaagaggat gaaagcgatc
    12661 aaagaatcat cctgatgctt tcaggaggct tgatggttca tctcggcttg atattattgg
    12721 cgatagtgtt tggatttttg acaagaagct ggtattttgc agggacttgg atttttctta
    12781 atttatcttt cttcctaaat aacattttac cagtcggcat caccgatgga gcaaaaattt
    12841 gggaattact acaacaccct gaaaatacca aatacgccta cctggtattg agacattctg
    12901 ctcaaacttt gctggctcct caagaatatg atttgaaaga ctttgttcaa gcagttcctg
    12961 aggatgcacg agggagtttt gcggatggtg tattaggtat gcaaggtgaa gtttccattt
    13021 tggaagggaa ggaagaagta gctaaacagc agtttcaagc attacttgag aggacaacta
    13081 ctccgatgat gcagacagtt gcccaactat ccctacttca tatcgccttg ttggaaggag
    13141 attttgagca agcggagcaa tatgctagta ttcgacaggt caaatcgttt ctgtctctca
    13201 aactgtccaa tcttcaagtg atacaagcct ggtatcaatt aaaggtgaag aaagatgtag
    13261 atcgaactcg taaggctctc aagattgcta gacagaaaat ggatagtagt cgaatgttga
    13321 gggacgagaa acgctattat gaaaacttgt tagcagagct ggaaaaggaa ttagccgaag
    13381 gagtctaata tggaaataga gatttctgat ttcacaggtt gcaagattgc tttgttttgt
    13441 ggggataagc ttttgactat cttacgcgat gataaggcaa gcattccctg ggccaatatg
    13501 tgggaactgc caggtggggg aaagagtgtc agggaaaatc tgatatagtt ttgcattaaa
    13561 agaatatcct ttcaaggtta ttctttttta attttgtccc aaaataattg actttgtccc
    13621 ggaaatatag tattatttgt ataaggagga atgaatcatg aaaaaatcag atgttcttga
    13681 tttaataaag tatcattatg agggcagaga gacagaattt agaaatcaat ccatagcaat
    13741 tgctcggaac ttcaataaac atggtgatac acaaatagca caatatatta tggggttaat
    13801 gtctcaaagt gatagattca tgccacaaat agaaaatcct agtgagtatt tgactcctgc
    13861 taaactagat attggtcctc tcccattgcc tctttcaatt atgaatgatt taaaaggaat
    13921 aataaacgct gtcaatcatc atattggaat aaataaattt ttatttgtgg gatctccagg
    13981 tactggaaaa actgaaagtg taaagcaggt ggctagactt attggcaagg aattacttgt
    14041 agtagatttc agtcacttag tagatagtaa gctagggcaa acagtcaaaa acttagcaac
    14101 tctttttaat gaaatcaata atcttccttt caagcaaaat tatatcatcc tatttgatga
    14161 aattgattcc atagtgttgg atagggttaa tcagaatgat ttaagagaaa tgggacgagt
    14221 gacttctgcc tttttaaagg agttggatag gctgtcacca gaaattgtat taattgcaac
    14281 aacaaatctt tttgaaaatc ttgataaagc agttacgaga agattcgatg ccataattga
    14341 ctttgaccgt tatactgatg aagataaagt agaagtagct actattattt taaatgagtt
    14401 attaaagcaa tttaagaatg tagctagaga tttaaaatta tttaaaaaaa ttatcaatag
    14461 tgccaatgta ataccgaatc ctggtgattt gagaaactca ataagaacgt cattggcatt
    14521 tagtgatcca tcagatccgc atgattacca aaaacgcctg ctaagaagtt tgcataatgg
    14581 tagaaattta tctatttcta aattatcgaa gctaggtttt actgttagag aaattgagat
    14641 tttgacaggt gtttctaaga gtagtgtatc acgagagtta agcgaggatt aaaatgaata
    14701 cattattgac attacgaggt aaaagcttta cacaaaaatc aagaaataat ggtatgggac
    14761 caataactat acccaaaaaa acaataatta cattggaaca tttgaagtat cttcattttt
    14821 cattagaaga gacgaaaaca tattgggaga aaaataacat tatcgatggt attttgatca
    14881 gtatttacta taatcgaatt gttgccaaaa gtaaccgtat taatggctat ttcaatgtag
    14941 gaggagggaa tccattccct aatgatacta ttgtgggagc aaaattcaat gatgagaaga
    15001 caaaacatat tgttactcat tatatttcta gagatgctct taataaaaca ataaccgttt
    15061 taagtaagat aattgaagtt tttgaggaac attttgatag agcgataaca tgtgagatgt
    15121 tttctgattc atcaacgttt gcttctataa atttttcgga gtatggtatt tcaaaaagca
    15181 aatttcaaca gtatttgaga gattcttgct ttattgagaa ttttggagtt gagcacacta
    15241 ctgtttctga tattcaaaat tctatcgtga cattttatga tgtccataca gacattttta
    15301 gattactgaa taaattaaat attgatattt cagaagctaa tatcatgaat cagaccacgg
    15361 tcttgcttga tgaaaaaaat attgaattac tactatcaaa agcgccctat cttgtctcca
    15421 tgattgtgga agatttttct aagttatctg tagatgattt ttctttagat aataatgatt
    15481 taaaaataaa tcttccatct ccaatgaacg aaccagttgt tggcgttatt gataccttat
    15541 ttgacaaaag agtttacttt aatgagtggg tagaatatca tgattttgtc tcacctgata
    15601 ttagcaaaga tagccaagat tacaagcatg ggacagctgt gacttcttta atcgttgatg
    15661 gagccaattt gaaccctaat ctggatgatg gttgtggaaa ttttagagtg aggcattttg
    15721 gtgtgtcact acaaagtgga tttaattcat ttacaatcat aaaacagata aaagagattg
    15781 tttctcagaa tgctgatatt aaggtttgga atctttcttt agggtccaat gatgaaataa
    15841 gagaaaattt tatctctgca gagggagcat tattagacga aattcaattt gagaatgatg
    15901 taatttttat catagctggg acaaatgctt cagtaataaa tgggaaacgc aaaagaatag
    15961 gtgctcctgc tgattcactt aattctataa tagtaaattc tgttgatttt aataatcaat
    16021 cagtgtcata ttcacgagag ggtattgttt tatcattctt tgttaaacca gatgtgtcat
    16081 attatggagg aggaaatggt gactttataa atgtttgtga acctctagga ttaggtcgtg
    16141 tagctggaac aagttttgcg gcacctttta ttgcaaggaa aatggcctat ctcattcata
    16201 ttatgggact tagccgagaa gaagcgaagg ctttgctaat tgatgcagca ataccctgga
    16261 atgataagaa aacattcact gatttatctt tgataggaaa tggtattgtt ccaataaaaa
    16321 tggatgatat tttatctaca cctgatgatg aaattaaatt tattgtgtca gatatctcta
    16381 gggcttatga tacctataat tatgattttc cagtacctat ttctagtgag agttatccat
    16441 atgtagctaa agcaacaatg tgttatttcc ctaactgctc aagaaaacaa ggggttgatt
    16501 atacaaatac tgagatgcag cttacttttg gtaggttaaa gtcagacggt atcaaatcga
    16561 taaataaaga caaccagcat gccgaagatt ccccaggata tgtgagagaa aatgctgcta
    16621 gaaatatatt taggaaatgg gataatgtca agcatattgg agagtcgttt acttctcgaa
    16681 agagagctaa agcaatttta aatccatcta atcctcagtg ggggatgagt attaaaacaa
    16741 tcgaacgttt gaaaagcggt gatggacaag gagtacgttt tggtgtagta gttacattaa
    16801 aagaattaaa tggggttaat cgtattgaag attttattca gcaagctgaa ttacgcggtt
    16861 ggctagttaa tagattgcaa gtagaagctc aagtagacct ctttaatagt ttaaatgaag
    16921 aaattgaatt tgaatagtgg atattttatc cttattttag atcttaggaa cacaagaggg
    16981 caaagatatg aatattactt atatagttgg aaatggtttg gatttgcaat atggtttgaa
    17041 aacaagatat agggatttct acgaattcca aaataaggtt tatataagta ggacagagaa
    17101 cgaggaaaaa tattcaaatt tcatttatga gtctctattt tctgatacag taaatgatta
    17161 tgaaaattgg tcagattttg aattgtcaat tggtaaatta acaaaagata acgacctcat
    17221 ctcctcaagt atagaaataa aggagaaatt tatagatgat tttagtgaaa tagttgatga
    17281 tttaagagaa tatctacgca tacaacaaga aaaaaatctt gagaaaggta atgcaattga
    17341 ctttataagc actctagata atatgaggac ctctctccct gtaattaatc aacctgctat
    17401 cgataaaaaa tataatgaaa atctatatca acacgatatc gtgaatatat taactcttaa
    17461 ttacacaaat gtaatcgata aattatataa tgagtcagca aaatcattta gcaatcaatt
    17521 acgaactaat aattataaat ttcacattgc gcctccaatt catgcacatg gaacggtaga
    17581 tatttgcaca gttttaggag ttagtgacga gacacagatt tcaaatagtt ttgatgaaga
    17641 acaaaaagaa tccttaataa aaaatttagt tttgaagaac tatagagaaa atatggatgt
    17701 taaaaatagc gatattataa aaaattctga catcataatt ctttatgggg tttctttggg
    17761 agagactgat gggtatatct ggaatcagat tgctgaacaa tcaatcagaa gttctgttcc
    17821 tgtcataatt taccattatg tacctcattt tgatgcagga aaccccacta gagtaaaacg
    17881 cttatataga aatgtagaag acaaattcat acaaaatagt ggaattgatt tagagttaga
    17941 gaagaaatta agagataacc ttattgttgt tattggaaag actattttta atctgatgga
    18001 aaggtaagca aaatacataa tggaaacatg gcaagagtta aaagttacag tgaagcgtga
    18061 gggagaggag ttggtttcca atctcttgat tgagctggga gcgcaaggag tcgcaatcga
    18121 agacagtatg gactatgtgg gaaatgttga ccgctttggc gagattttcc cagaggtgga
    18181 gcagcaagaa gaaatcgtag tgacagccta ctaccctgac acggtggatg tgacagtggt
    18241 tgaggcggat ttgcaggctc gtctagcaga attgacagat tttatggatt tgggagagtt
    18301 aaaaataggt acgactgcct tggctgagga agactgggca gacaactgga agaaatacta
    18361 tgaacctgct cgcatcactc atgatttgac catcgttccc tcttggacag actatgaggc
    18421 gactgcggga gaaaaaatta tcaagctgga tcctggcatg gcttttggta cgggaaccca
    18481 cccaactacc aagatgagca tttttgcctt ggaacaggtt cttcgtggtg gcgaaacggt
    18541 gctagatgtg ggaactggtt caggggttct ctctattgcc agctcgcttc tgggggctaa
    18601 agaaattttc gcctatgacc tggatgatgt ggcagttcgt gtggctcagg aaaatattga
    18661 gctcaaccct ggaatggaaa atatccatgt agtggcaggc gatttgctta aaggcgtgga
    18721 gattgaagca gatgtcatcg tggcaaacat cttggcggat atcctcattc atctgacaga
    18781 ggatgcttat cgcttggtta aggatgaagg ttacctgatc atgagtggca ttatcaagga
    18841 taagtgggac atggtgcgcg agttggctga atcagctgga tttttcctcg aaactcacat
    18901 ggttcaaggg gaatggaatg cctgtgtctt taagaaaacc aaggatatct ctggtgtgat
    18961 tggaggctag catgcagcag tattttgtaa aaggcagtgc tatctctcct gtcactatcg
    19021 agaacaagga aaccagtaag catatgtttc aggttatgcg cttgaaagaa gaggatgagg
    19081 ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg cgtgctggat atggaaaatc
    19141 gtcagtttga gttggtccaa gaattaaatg acaatgtgga actaccagtc caagtgacca
    19201 tcgcatctgg atttcccaag ggagacaagc tggagttcat cgctcaaaaa gtaaccgaac
    19261 tgggtgctag ccaaatctgg gcctttcctg cagactggtc agttgccaag tgggatggca
    19321 agaaattggg taaaaaagtt gaaaaactag aaaaaattgc ccttggagca gccgagcaaa
    19381 gcaagcgtaa tattgtacca agtattaaac ttttcgagaa aaaagcagat tttctagctc
    19441 agctggacca gtttgactct atcatagtag cctatgaaga atcagctaaa gaaggagaag
    19501 ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg agccaaactg ctctttatct
    19561 ttggtccaga aggcggtctc tcacctgcag aaatcgaaag ttttgaagct aagggagccg
    19621 ttttggcagg cctaggtcct cgtattttgc gagcagaaac agcaccgctt tacgctttat
    19681 cagcccttag tgttttagta gaattagaga aataagagga agaaaatgga acaaaaacac
    19741 cgttcagaat ttccagagaa ggaactctgg gacttaacag ccctatacca agaccgtgag
    19801 gatttcttgc gtgcaatcga gaaagctcgc gaagacatca accagtttag ccgtgattac
    19861 aagggcaatc ttcacacttt tgaggatttc gagaaggcct ttgcggaatt ggaacagatc
    19921 tacattcaga tgagccatat tggcaactat gcttttatgc ctcagacgac ggactatagc
    19981 aatgacgaat ttgccaatat tgcccaagct gggatggaat ttgaaacagc tgccagcgta
    20041 gccttgacct tctttgacga tgccttggtg gcagcagacg aggaagtctt ggaccgtttg
    20101 ggtaaattgc cacatttaac agctgccatt cgtcaggcta aaatcaaaaa agcccactac
    20161 ttaggggcag atgtggagaa ggccttgaca aatctcggtg aagttttcta tagtccgcag
    20221 gacatttata ctaagatgcg agctggggat tttgaaatgg ctgactttga agcccatggc
    20281 aagacctata aaaacagctt tgtcacctat gagaatttct accaaaatca cgaggatgct
    20341 gaggttcgtg agaaatcctt ccgttccttc tcagagggac ttcgtaagca ccaaaatacg
    20401 gctgcagcag cctatctggc tcaggtcaag tctgaaaaac tcttggctga tatgaaggga
    20461 tatgactctg tctttgacta tcttctagct gaacaagaag tggaccgtgt catgtttgat
    20521 cgccagattg acctcatcat gaaggacttt gcaccagtcg ctcagagata cctcaagcat
    20581 gttgccaagg taaatggtct tgaaaagatg acctttgcag actggaaatt ggacttggac
    20641 agcgccctca atcctgaagt gactattgac gatgcctatg atttggtcat gaagtcggta
    20701 gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt accaagaaga gcgctgggtg
    20761 gactttgctg ctaacagtgg caaggattcc ggtggttatg cggcggaccc atatcgcgta
    20821 cacccttatg tactcatgag ctggacaggc cgtttgagcg atgtctatac cttgattcat
    20881 gaaatcgggc attctggtca attcatcttt tcagacaatc atcaaagcta tttcaacgcc
    20941 cacatgtcga cctattatgt tgaagcaccg tcgaccttca atgaattgct actcagtgat
    21001 tacttagaga accagtctaa tgacccacgt caaaaacgct tcgctctggc tcatcgcttg
    21061 acagacacct acttccataa ctttatcacc cacctcttgg aagccgcctt ccagcgtaag
    21121 gtgtatacat tgattgaaga aggagagacc tttggagcaa gcaagctcaa cagcattatg
    21181 aaggaagttt tgacggattt ctggggagat gctattgaaa ttgacgatga tgcaactctg
    21241 acttggatgc gccaagctca ctactatatg ggcttgtata gttacactta ctcagcagga
    21301 ctagttatct cgactgctgg ttaccttcat cttaaaaact cagaaactgg agctgaagac
    21361 tggctcaatc tcctcaaatc aggtggtagc aagacaccac ttgagtcagc catgattatc
    21421 ggtgctgata tttcaacaga caaaccactc cgtgatacca tccaattctt gtctgacaca
    21481 gttgaccaga ttatctccta tagtgctgag ttgggggagt aaggggaata gaaaaatttt
    21541 ctagaatgat gtttatgggc ttgttaagcg tcattctatt tgtcttagtt gtagctattt
    21601 tcaaaaatgt cgttgaaggt cgtgatgtta aatttgaact tactgtagaa ctggtattga
    21661 tagttattta cgtcatttta tatcagattg tatttaattg agaattcaat attgagtcat
    21721 ttaagactgc ctttttgaac agttgctaga aatgtagagg tattgaccat gtatcaagat
    21781 ttactaagaa aaatagcaga agaaaaacca aattataacc aggaggaaat ccagtggttg
    21841 cttgatcatt tgggagatcc ttctccagaa attcgtgatg atcttgtttt tacaagcttt
    21901 gctagaggga ttcaggaaga gctatttaca caggaacaat ttcatttcat tgctgaggtg
    21961 gtcttagctg atggagggtt agataaagag attgataagg taggcttgtc aacacttgaa
    22021 cgttctttta gggcacttat ttatgcaaat ctcttgtctg cagatgctaa ccagcaatcg
    22081 gttttttatc agggattaca atcagaaatt cgtaatgtcc ttttaaatca aggcttgcac
    22141 tatctttcaa aagaaaagga tacaacaggt ttctcaagtc agtatggttg ggttcattct
    22201 tttgcacatg gagccgattt actgaaagag gtggtttgtc atccagactt tcctaaaaac
    22261 agagttcatg aagtatttga tatacttggc caactattta aaagaatgtc gattcgcttt
    22321 acagatgatg aggattggcg tttagcaaga gtgatctatg aacctatttt acaagggaag
    22381 ttggagcaag aacaagtagc ttcttggata aaaactgttg attttccgat agaagaaagg
    22441 gaggattttt acaaattttc caactttaga tcctgtctgg tggaagtcta tgtccaactt
    22501 gaccagagaa atagtttaca agatgacctg aaagaagcta tccagtcttt tcaatactag
    22561 ggattagcta atagttctat gattttcaaa aaatttccaa tcaattttct tgaaaccctt
    22621 tcctactttt gatagactag tatctagttt ttgaaaaaag gagaaagaaa atgaaaaaat
    22681 ttgttgctga gttaatcggt acgttcatgc ttgtattcgt cgggacagga gctgttgttt
    22741 ttggaaatgg tcttgatggc cttggtcacc ttggaatcgc ctttgccttt ggtttggcaa
    22801 tcgtggtggc agcctactca atcggaactg tttcaggtgc tcacttgaac ccggctgttt
    22861 cgattgctat gtttgtaaac aaacgtttgt catcttcaga acttgtaaac tacatccttg
    22921 gtcaggttgt tggagctttc atcgcttctg gcgctgtctt cttcctcttg gctaactcag
    22981 gtatgtcaac tgctagtctt ggtgaaaatg ccttggcaaa cggtgtcact gtctttggtg
    23041 gtttcttgtt tgaagtcatc gcaactttct tgtttgtatt ggttatcatg actgtgactt
    23101 cagaaagtaa gggcaatggc gcgattgctg gtttggtaat cggtttgtca ttgatggcga
    23161 tgattcttgt cggattgaag attactggac tttcagtaaa cccagctcgt agcttggcac
    23221 cagctgtctt ggtgggcggc gcagcccttc aacaagtttg gattttcatc cttgcaccaa
    23281 tcgctggtgg agttcttgca gcccttgttg caaaaaattt ccttggaaca gaagaataat
    23341 tgaaactcaa aaagccttgc tcctcatctt gaggaacagg gctttttcgt atgatactct
    23401 tcgaaaatct cttcaaacca cgtcagcttc accttgccgt aggtatggtt actgacttcg
    23461 tcagttctat ccacaacctc aaaacagtgt tttaagctga cttcgtcagt tctatccaca
    23521 acctcaaaac agtgttttaa gctgacttcg tcagttctat ccacaacctc aaaacagtgt
    23581 tttgatctga cttcgtcagt tctatccaca acctcaaaac agtgttttaa gctgacttcg
    23641 tcagttctat ctgcaacctc aaaacagtgt tttaagctga cttcgtcagt tctatctgca
    23701 acctcaaaat agtgttttga tctgacttcg tcagttctat ccacaacctc aaaacagtgt
    23761 tttgagcaac ctgcggctaa cttcctagtt tgctctttga ttttcattga gtatgacttt
    23821 agcggttgtc aattttctct ggataaaggt cgtgttggaa gaggcgttgt tctgccaagc
    23881 cctcatactt agttccttgc ttaccgtagt tgtagtaggg gtcgattgaa atgccaccgc
    23941 gcggagtgaa ttttccccag acttctaaat agcgagggtc tagcaagttg accaagtctt
    24001 tcccgatggt gttgatacag ttttcgtgga aatctccgtg gtttcggtag ctaaatagat
    24061 atagtttgag ggattttgac tcgacacaga gcttgtcagg aatgtaggaa atatgaatcg
    24121 tcgcaaagtc tggctgagca gtgatttgtc ccagcagaga catatcgagg atatggtgac
    24181 gaatgccctg ttccttagcg atttctctag taatttgaat ttcgaggtga tgacgttggc
    24241 cgtaggcaaa ggtgacagct tcgactgttt catagtattg catggcccag aaaaggcagg
    24301 ttgttgaatc ttgaccacca ctaaagacga ccaaggctga ttgacgtttc atagtactcc
    24361 ttccaaaatg ggaaatgttc agagcacgca aaaagctccc attagggagc taaaaaatac
    24421 caaatcgagg tttttttagc gatggcatat cccaaacatc gtaatattct acttatatag
    24481 taaaatgaaa taagaacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
    24541 tttagaagta gagatgtact attctagttt caatatacta tagtctagca tattttttga
    24601 aaaatggcaa agggcaagaa aaaagagacc aaagaaagta cttggtctct cgtttgatta
    24661 gctcaattca gcaatgatgg ccttgatttg ttctgctgtg tgaacacctg caacttgttt
    24721 gacaacttgg ccgtcttttt tgaagagaag agttggaata gacatgattc caaaagcacg
    24781 agctgtgttt ggattttcat caacgtccat tttaacgatt ttcaagacat cttctgaaag
    24841 ttcttcagac aatttgtcca agattggacc ttgcatacga catggaccac accaagttgc
    24901 ccagaagtct actaagacca aaccgtcttt tgtttcttgt tcgaatgttg catctgtaat
    24961 tgcttttgcc attgtatttc tccttttttt agttatattg gcttaaatct tgtttcatga
    25021 gatagaagaa gatatctcca taagtcccat ggtagtccaa attatgaccc ttgtaggtta
    25081 atttttggac agggtagtag tctgcgacgc cgataaggca agcttgttgc gaacgttcaa
    25141 agtcttcata agactcgaaa gtcacagttc tttcgttctt gctggcatct atataggtaa
    25201 tttcaatcat atttaaaact cctttgttta atgctaactt tattttactc cttataaaag
    25261 agaatgtcaa gaaaaatgat tgcgcacgca acttttttta aaatcatctt aaatcaagaa
    25321 atccaaacct gcttccaagc tttcttcgac agtcttttgt agcgaggcca gtgtcttttg
    25381 cccatcattt gtcaggcaga taaaactaga gcgtctatct tgatggcaac acatgcgact
    25441 gagtagaccg caatttttag cttccaagcg agccaccatc ctagaaactg cgctcgggct
    25501 cagatgaagc ttatctggca ggtcaatctg gcgtagagat ttttcttcag ccaagtccag
    25561 atagtagagc aggtagaact ctttcaaggt cagactttgc tcgctctgtt gggcaatggt
    25621 ctcttccaag agactttcaa tttctttctg acgccgattg aagtcaaacc atttttccaa
    25681 ataggtcata gtgtctcctt tctttttaga gtcataatat agaagaaagt ccattaacgg
    25741 gcagtctctg cgtcacaaga tgattgcgca tgcaataatt atactacttt tcaagaatgc
    25801 tggcaagctc tgttttttag tggttttatt tttgtgtgaa taatggggga atcctattgt
    25861 ttcaatttct aactccttat cacattcgaa tttagatttt atttcatttc tctatctata
    25921 gttgcttagt ttaaaataag catggtctaa taaagctatg gcatatagta ctgattttaa
    25981 acaaggagca ttagattcca tcaaagaggg gcacagtcat gtcgaggcag ccaagttttt
    26041 tggtgttggc gtcagaactc tcttcacgtg ggaaaagaaa gacgtgaaca agaacacata
    26101 gagaggaaaa agcgagtcgt caaaaaccga aagattcctt tagaggaatt gaaagccttt
    26161 gtagaggctc atccagatgc ttttttacgg gaaattgcgg cacattttga ttgtgctgtt
    26221 ccttcagtat gggcagcttt aaag
//
LOCUS       DAVLHB010000027        25858 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLHB010000027 DAVLHB010000000
VERSION     DAVLHB010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.027"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(106..255)
                     /locus_tag="VXE36_001254"
                     /pseudo
     CDS             complement(106..255)
                     /locus_tag="VXE36_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(409..2040)
                     /gene="rlmD"
                     /locus_tag="VXE36_001255"
     CDS             complement(409..2040)
                     /gene="rlmD"
                     /locus_tag="VXE36_001255"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0779561.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LHKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSQKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2114..3088)
                     /locus_tag="VXE36_001256"
     CDS             complement(2114..3088)
                     /locus_tag="VXE36_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0779562.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3162..3776)
                     /gene="pmp23"
                     /locus_tag="VXE36_001257"
     CDS             complement(3162..3776)
                     /gene="pmp23"
                     /locus_tag="VXE36_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0779563.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3776..4750)
                     /locus_tag="VXE36_001258"
     CDS             complement(3776..4750)
                     /locus_tag="VXE36_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0779564.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4758..6014)
                     /locus_tag="VXE36_001259"
     CDS             complement(4758..6014)
                     /locus_tag="VXE36_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0779565.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6076..6507)
                     /locus_tag="VXE36_001260"
     CDS             complement(6076..6507)
                     /locus_tag="VXE36_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779566.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6509..7108)
                     /locus_tag="VXE36_001261"
     CDS             complement(6509..7108)
                     /locus_tag="VXE36_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0779567.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7095..7934)
                     /gene="prmC"
                     /locus_tag="VXE36_001262"
     CDS             complement(7095..7934)
                     /gene="prmC"
                     /locus_tag="VXE36_001262"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0779568.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7934..9013)
                     /gene="prfA"
                     /locus_tag="VXE36_001263"
     CDS             complement(7934..9013)
                     /gene="prfA"
                     /locus_tag="VXE36_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0779569.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQNEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9023..9502)
                     /locus_tag="VXE36_001264"
     CDS             complement(9023..9502)
                     /locus_tag="VXE36_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779570.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTALAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(9492..10091)
                     /locus_tag="VXE36_001265"
     CDS             complement(9492..10091)
                     /locus_tag="VXE36_001265"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0779571.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10214..10396
                     /locus_tag="VXE36_001266"
     CDS             10214..10396
                     /locus_tag="VXE36_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0779572.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10533..11906
                     /gene="mnmE"
                     /locus_tag="VXE36_001267"
     CDS             10533..11906
                     /gene="mnmE"
                     /locus_tag="VXE36_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0779573.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11953..12888)
                     /gene="dapA"
                     /locus_tag="VXE36_001268"
     CDS             complement(11953..12888)
                     /gene="dapA"
                     /locus_tag="VXE36_001268"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0779574.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12944..14020)
                     /locus_tag="VXE36_001269"
     CDS             complement(12944..14020)
                     /locus_tag="VXE36_001269"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0779575.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14605..14677)
                     /locus_tag="VXE36_001270"
     tRNA            complement(14605..14677)
                     /locus_tag="VXE36_001270"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14642..14644),aa:Thr,seq:ggt)
     gene            complement(14777..15286)
                     /locus_tag="VXE36_001271"
     CDS             complement(14777..15286)
                     /locus_tag="VXE36_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0779576.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15284..15380)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15409..15840
                     /locus_tag="VXE36_001272"
     CDS             15409..15840
                     /locus_tag="VXE36_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0779577.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSRQELLA
                     TALANIIGILFAFITNDTIAFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15922..16299
                     /gene="mscL"
                     /locus_tag="VXE36_001273"
     CDS             15922..16299
                     /gene="mscL"
                     /locus_tag="VXE36_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0779578.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16341..17435)
                     /gene="hemH"
                     /locus_tag="VXE36_001274"
     CDS             complement(16341..17435)
                     /gene="hemH"
                     /locus_tag="VXE36_001274"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0779579.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWVDEIAKILKEEVKQD
                     SCKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17589..18812
                     /gene="pepT"
                     /locus_tag="VXE36_001275"
     CDS             17589..18812
                     /gene="pepT"
                     /locus_tag="VXE36_001275"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0779580.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITVAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18848..19180)
                     /locus_tag="VXE36_001276"
     CDS             complement(18848..19180)
                     /locus_tag="VXE36_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779581.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(19209..19466)
                     /locus_tag="VXE36_001277"
     CDS             complement(19209..19466)
                     /locus_tag="VXE36_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779582.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKVDADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLRK"
     gene            19431..19652
                     /locus_tag="VXE36_001278"
     CDS             19431..19652
                     /locus_tag="VXE36_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779583.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19761..20237)
                     /locus_tag="VXE36_001279"
     CDS             complement(19761..20237)
                     /locus_tag="VXE36_001279"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0779584.1"
                     /translation="MTPNNGVSAADDGYVFNPNDIVRDTGDAYIVRHGDHYHYIPKSS
                     LNNPPSHSNTEEAGSSSSSVLSNPSLHVHHEEEDGHGFDANRIISEDSEGFVIPHGDH
                     NHYIKVQTKGYEAALKNKIPSLQSNYQPGTFDEKAVLAKVDQLLADSRSIYKDRLS"
     gene            complement(20277..20417)
                     /locus_tag="VXE36_001280"
     CDS             complement(20277..20417)
                     /locus_tag="VXE36_001280"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0779585.1"
                     /translation="MLEITLKSPYQFAHILFQPTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(20461..21021)
                     /locus_tag="VXE36_001281"
                     /pseudo
     CDS             complement(20461..21021)
                     /locus_tag="VXE36_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(21247..24366)
                     /gene="phtE"
                     /locus_tag="VXE36_001282"
     CDS             complement(21247..24366)
                     /gene="phtE"
                     /locus_tag="VXE36_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0779586.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDFIA"
     gene            complement(24577..>25858)
                     /gene="phtD"
                     /locus_tag="VXE36_001283"
     CDS             complement(24577..>25858)
                     /gene="phtD"
                     /locus_tag="VXE36_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0779587.1"
                     /translation="SKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLD
                     NKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNSQITYTDDE
                     IQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAY
                     AKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLI
                     IPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDH
                     VQRNKNGQADTNQTEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKP
                     STDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLTGL
                     KSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT         7361 a         5373 c         4742 g         8382 t
ORIGIN      
        1 agcacaccaa ctatttattt tttgagtttt aaactttggt agaagtcttg aactccttat
       61 atttacataa ctatttgcct ctataactat tatgacacga aaccaacaag caagttcaag
      121 cacctccata tctttattca aatgaggact aagatattca caaactttat cataaacctc
      181 tttatctttt ttcataaaag gggcatacaa cttagcaaat ttatcctaaa attttttgtt
      241 gcctttatca atcatttcag cgctccttta aatataaaaa tgatcctatc aatctttata
      301 ttgagcctat tttctaattg ataccttgca agaaaggaat aatagctgtt cctataccaa
      361 gtaggaatgt aataaatgca gaaagtcata tactgtcatt cttttctatt aaatcatttt
      421 gaagtgtctc aaagcatcca tgatggcttc ttctttttca ggtgtacact gtggaataat
      481 ttgtttatcc ttttgagact tgttgtaatg ttctcgtaat tctattccac atttcttttt
      541 tatctgtgca atatataatg tcgaaacttt taattcaaat ttattccaaa catattcttt
      601 gatttgagca tatgttgctt tgctctccgc acttgtcaaa tccatctcat ccagctcaat
      661 ttcaacactt atgtgcttat cgacatcgag tttggacaaa agtgctaccg tctcgacgtg
      721 atgcgtttga ggaaatagat ccaccggctg gactttcttc aattcatatc ccaactcttg
      781 gtatagttta atatcacgcg ccatggttgc gacattgcag gagatatagg cgatgcgatc
      841 ggctcctgtt tgggcgcttg ctttgataaa gctttctgtc aagcccttgc gtggaggatc
      901 aaccaagata acggttggtt gaataccttc cttgagccat ttcttcatgg cattttcagc
      961 cgtgtcacag acatagtggg cattagtaat cttgttcaaa gaagcattct tctggctatt
     1021 ctctactgct tctggaatca gttcaacacc gtagacttct ttgacatgct tggcgactga
     1081 taaaccaatg gttccaatac cagaataggc atcaataatc acatcatctt tttttaactc
     1141 tgcaaagtca atggctgttt gatagagttt ctccgccatt tcagtattga cttggtaaaa
     1201 ggctgggcca gcgatttgga agtcatttcc caacatctgg tccgtaatat agtcttgacc
     1261 ataaagagtg cgccactcct taccaaaaat cgcattggta ttctggtcgt tgatattttg
     1321 catgacagac acaatctctg ggaactgctt gataacttgt tcaatcaatt ggtcaacacg
     1381 aaaaactttt ggacgagttg tcaccaaaac gaccatgatt tgtcctgaat agtgaccacg
     1441 acgcaccaca agattccgaa tcaatccaga ctgttccttt tcgtcataag gttttaaatc
     1501 aaaacgacgg agcaggtctc gaagagctac tacgacttgg tcaatgacag gatcctggat
     1561 aaagaaatct tcaaggggca tgaggtcgtg cgaattctta cggaaaaatc ctgtttccaa
     1621 gacaccattc actcgacgaa cgggcacctg cgccttattg cgatacttga ctggatgttc
     1681 cataccaagc gtttcagcaa cttctacatc tgcaattcca gcaatcttgt ggagactgtc
     1741 cttgacttgc tttgttttaa acttgagctg ttctggataa gaaaggtgtc ctaaatccgc
     1801 gattcctgaa cgcaggtaag ccaaatctag atcttgatta cggtgtggtg actggacaag
     1861 gtatttttca acttttccaa agccaatctt tttattgacc ttgaggacac gcatgagaat
     1921 tttttcactc ggtaaagcat tctctacaaa aaagaccaaa ccatctacct tggcaactcc
     1981 tgccccttca tgggtcaagt caacaatttc aacttctaca atatcatttt tctttaacat
     2041 tcttttctct ttctattggc cgacaaaaaa gacggcaacg ttacggttac catccattat
     2101 accatgaaat ttcttaagaa ccaaaactct tgaagaagtt gacaagggct tgccagaggg
     2161 agcttaagaa gttaccaccg tcctctagcg ccttatccgc atcaaagtta aggttgatat
     2221 ttttaaaact gtcgccagct tgtgatacga tgctttgttt aaggtcattt agggttttag
     2281 tgaaatctgc attgctgagg atatcactct ttgagagatt caaggcaaaa ttgatgatga
     2341 tattgatctg gtttcctgtt atgacctgat caagtttgta attttttaag gtatcttcaa
     2401 caatcttgcg gatatcttct tctgtcagat ttcccttgct ttctttagct ttggcgagtc
     2461 ctgacttgat atcagctagg gcaacgttta atttattagc atcatagcct gatttgtcct
     2521 tgttttcagc attgatatct gacaaagctt ttagctcttc ttgagccaaa tctttattag
     2581 cttgtggcac cttggctcca ttagcctcta gcgaatagta aatccctgct aaagcacttt
     2641 ctcctgtaac tggaataggg gctgctacag tgattttggc atgttccata cccagcgtta
     2701 ctgctgcgtt tcggtacata tcctgagtca ccttagtgat attttctggt gtttcaatct
     2761 tgacctcaag tggcgatttg tcacctagct tttgaatctt ggctgatgaa tacaactgta
     2821 agctagagtc attggccaca ttcatgattt tagaataaac atcaggtgtc atggtcttga
     2881 gttctttggt atctgttgag gcattgtagc ccagtttttt aagagtttga tttttttggt
     2941 cttcagatag ggaggaacct aggacatatt caggttggac ataggtttca tcgataactt
     3001 tttgaacatc tgttgctgca tggacgctat tcatagctgt tactgcccac aagaccgcag
     3061 cactagtcag aaagagtttc tttctcatag ggaatttcct cctttacttc tttatagtaa
     3121 tatatctatc ttaaagaaaa cttataacaa aaacacctgg tctagccaga tgttgaaaag
     3181 agagtgaaac atttgatgat gtaaaggtta agtcgtacct gtctagaata ataataattt
     3241 cctccattta catagagttc agcaccgtga aaaatggaaa tggggtgaat ataactataa
     3301 gtctttccag tcgtattacc aagcaagggg gcaacagtct cacgagagta ctgtttggct
     3361 agagccaagg tattttcctt gccattttgg gcgataaaat cgatataggc aggtccaaaa
     3421 ttataggctt gaacagctgt ccagatatct acccccttct tctgcgccag atagagattg
     3481 cctgtcagag tttgaatgcc ttgccgaatg ctagaggcat tatcattgat ggtgttggtg
     3541 gaaccacttg cagactcact agactgcata acatcgcctt cttttccttt tgtttcagta
     3601 taaatcatag caagcacaag ctcttcgttt gctggggtgt ctttttcact caagatttct
     3661 cgcaccatgg gttgataggt catgacttgt ttgacatctt gatgaacgcg gtaagcttta
     3721 tagccagcaa aaaggaagac tgctagtaca agcactcttc gaattcgttt aaacattatt
     3781 tactttggat atcctcgata tttttgatta agatagagta ggttccattt tcgttttgga
     3841 taaactcaac agactcggcg tcttgataga cgttattggg aacgatgagc tcaattccat
     3901 ttgataagga gagtttttgg ttttcaaatt tctttaattg gcgactggca tcaatttcat
     3961 caaattgaac aggttctggt acggcttctt tgacttggtc aataaagctc aaacgagccg
     4021 tcagattgtt gtcaaaaagg tcattagcca atttctcagg tgacaattca ttgctttctt
     4081 ctaggttgtt gaaaatcgct gatttgacct tggattgaaa ttgaaaatca tctgtgttaa
     4141 aagattcagc aattctctgg gctgtttttt ccagttcctt gatagatttt ttaggagaaa
     4201 tcttaggagc gacagcaaga agattatctg aaaaatagtt caaaaaagtc ccgttgtact
     4261 tgattcgttt ttcaatcagg tgatacttgc gactctgaag attgaccacc aaggcctcgt
     4321 cagcacccgt tccaaatcca ggcaggttat tctgagtcag cttgattgga ttatcaactt
     4381 ctcctccgag gtgggtcaag gtctcccgca gggcaattcg caagaaagcg aaatgttcta
     4441 caccttcttt agaaaattga acaaaaatca agtcattggt cttgagattt tcagaaatgc
     4501 taaactcctc tttccagaga ttagccagcg ttactgatgt ctccaacaaa tcgtctgtaa
     4561 tatgattgaa gaagggattt tcttcttcga aaatcccagt cttggcttca tctgaataca
     4621 catgttcaat ttttttacgt aggtattctt cgatttttgg agtaatattg agaaacttat
     4681 ctgctaagaa cagctcggta tcatccggac tgaactggtg aataatggct ttcttaatat
     4741 aaatgtccat aaaagtttta ttcctcgtat aatgggaagg catctgtcaa ttctttgact
     4801 gcacttctca cttcttctaa tacagcctca ttttctgaat tcttaagggt tttaatgatg
     4861 agttcagcca ctttgcgact ttcttcttca ccaaatccac gtgcagtaat agctgctgct
     4921 ccgatacgaa tcccacttgt cttgaatggt gacaagcttt cgtaagggat tgaattttta
     4981 tttagggtaa tattgacttc atccagcaag ttttgagcaa cttttccgtt ttctacaacc
     5041 ttagtcacat caacaaggaa gagatggttt tcagttccac ctgaaataat acggaaatca
     5101 gggtcttgca agaagacatc tgccatagcc ttgctgttct taattacatt ggcagcatat
     5161 tccttgaaag ctggatccaa aacttctttg aaggaaactg ccttagcagc cacaacatgc
     5221 tccaaaggac caccctgaat accagggaaa atagctgaat tgattttctt agctaaatcc
     5281 tcatcattgg tcaaaatcaa accaccacga ggaccacgaa gggttttgtg ggtcgttgtt
     5341 gtagtgatat gagcgtatgg cactgggctt gggtgaagac cagctgcaac caagccagcg
     5401 atgtgggcca tatcaaccat aagcttagcc ccaacagcat ctgcaatttc acggaatttt
     5461 gaaaagtcaa taatttgaga ataggctgaa gcaccagcta caatcagttt tggttttact
     5521 tcttgggctt gtttcaagat agcatcaaag tccaaaagtt ccgtttcagg atccacacta
     5581 taggaaagaa agttgtaggt ttgaccagag aagctaactg gagctccgtg ggtcaagtgt
     5641 ccacctgctg ccaaatccat tcccataacc gtatcacctg gctcaatcaa ggacatgtaa
     5701 gccgcacagt tagcttggct tcctgaatgt ggttggacat tggcaaattt agcaccgaaa
     5761 atttcttttg cgcgttcaat agcaagagtc tctacaacgt ctactacatc agttccacca
     5821 taataacggc gtcctgggta accctcggca tatttatttg tcaagataga cccttgagct
     5881 gccataacag ccttggaaac tacgttttcc gaagcaatta actcgatatt attttgttgg
     5941 cgttcttctt ctttggcaat agcattccag agatcagcat catatgcttt aaaatcatct
     6001 ttgtcaaaaa tcataggtct tctcctttat tgtgtgacta gtccattagt ttgattttac
     6061 agtaagaaaa tcaaactaaa agatgcgaat aaaccgtttc tgcattttat cacaagtata
     6121 gccaactttt tcataaaatg catgagcacc cagacgatga ttggcagaat ttaagcggat
     6181 aaacccataa ccacatcttt tggcttcttg ttccaaccct tgtagtaaac ttttaccgat
     6241 accttgacct tgcgcttgag gtgaaactgc taaagctaag atattaaatc ctgctttgga
     6301 atagagtgat tcgtaaactt cagcgtggac atatccaagt aagacatgat tagctgcatc
     6361 ctcatagcca agtaggaaat gatgggaatc ctgagacagt ctagctagtt ggctagccgt
     6421 ttcctctgga ctaaaagtat aacccaaagc ctcttggttg atgtcacata tcgctttcac
     6481 atctgtttct tgcaaatctc ttagcatttc aagcctcctc aaaagaaatc tctggcaacc
     6541 gagcaagaat atcttctcgt ttaattgcgc cttggcgtaa gattttcacc ttgtctccag
     6601 acaaatccac aatagttgaa tcctgtccag ttagaaaagc atcgtcttcc agacccagaa
     6661 cctcttggtc aaaatccttc agaatttgtt caaaggttac accacttgcc tgacctgaga
     6721 tattggcaga cggcccaatc aagggacctg tctctcgaat taaatccagt gtgatagggt
     6781 gactgggcat ccgaaatcca atagttgcaa ggtcagaatt tacccaatag ggaactcggt
     6841 cattggcttc gagaataatg gtcaagggac ctggcaaaaa ggtctctaca agtttttgta
     6901 gataagctgg ctgattctta gaaaagtgca agatatcctc taaagaggca acattgagat
     6961 tgagcgcctt gtctctagga cgacgtttga gctggtaaac atggtcaact gctttttcgt
     7021 ctaaggcctt ggcaaaaaga ccataaaccg tctctgtagg cagaatgaca gctccaccat
     7081 tttccaactc ttgtctaatc ctgtccatca tcaaccacga ccatcctatc ttgaccaaat
     7141 tggtccttga gtgttcgaac ttttttttca ggaagatgtt ttctaaaaag ttcgggaaca
     7201 ctttgacctt gcttgtatcc aatttcaagg taaatcttac caccatcttt gagatagtct
     7261 tttgcatctt ccgcaattct acggtaaata gctaggccat cctcgtctgc aaagagagct
     7321 agatgaggct ccgaatacaa gacattcaag cctacctctg actcatcttc acgagagata
     7381 tagggtggat tggaaacaat tatatcatat ttttcagaaa tttctgtaaa acagtcagat
     7441 tttttaaaaa atatttgaag attttgattt ttagcatttt cgctagctaa atctaaagcc
     7501 tcttgagaaa catctgctgc tgtcactgac caatctggtc tattttttgc tagagcgaga
     7561 gcaatagctc cactacctgt tccaatatcc agaactgaaa gattcgtctc aagattttca
     7621 gttagaataa gctccactaa ctcctctgtt tctggacgag gaatcaaaac ccgttcatcc
     7681 acctttaaat gcattccata aaaatctgcc tgtccaatga tgtactgagc tggcttgtga
     7741 gctgctagtt gctggtaaat atcttctaca aattgttttt cttcctctgt tgtcacctcc
     7801 tgctggaggg caaaaataaa gtctgtaaaa gatagatttt tcagactacg atagacaaaa
     7861 gagaggcttt ccgcttcctc tccttgtctt atcaactctt cttcaaaatt tgaaaataat
     7921 tgagctaatt tcattatttg tttaattctt ctagtttttg tgtttggtca taaagcacca
     7981 aggcatccac aacttcgtcc aatttaccag acaaaatcgt atctagtttt tggagggtca
     8041 agccgatacg gtggtctgtg acacggtttt gtgggaagtt ataagttcgg atccgttctg
     8101 aacggtcacc agtaccgatt gtcgacttac gctcagcgtc ttgttcattc tgagcaatct
     8161 gagcaaagtg gtcagcgacg cgtgcacgga taatcttcat agccttctcg cggttcttct
     8221 gctgggtacg ttcttcctgc atctcaacct tgatattggt tggcaagtga acgatacgaa
     8281 cggcagtcgc aaccttattg acgttctgtc caccagcacc agaggcgtga tagatgtcga
     8341 cacgaaggtc ttttggatca atgtcgtatt caacctcttc aacttctggc ataacaagaa
     8401 ctgtcgctgt cgaagtatga acacggcctt ggctttctgt cacaggaaca cgttgcacac
     8461 ggtgggcacc tgattcatac ttaagcttag agtatacaga ctgacctgaa accatagcaa
     8521 ccacttcttt aaaaccaccg acaccattca tagaggcttc catgacttca aagcgccaac
     8581 cttgggcttc cgcatacttt tggtacatag ttagcaaatc tccagcgaaa agtgccgctt
     8641 cgtctccacc agctgctcca cggatttcaa ggatgatatt cttgtcatcg tttggatcct
     8701 ttggaaggag caaaattttc agtttttctt catattcttc tttttcagcc ttggcatctt
     8761 tgagttcttg cttggccatt tcttccaagt ccgcatctcc gcctgattcc ttaatcatct
     8821 cttcggcatc gacgatattt tgaaggactt gtttatactc acggtaggct attacggtgt
     8881 cacgattgga agcttcttct tttgaaagct ccataaaacg cttggtgtct gaaacgacat
     8941 cagggtcact cagcaattct cctagttctt cataacggtc ttctacagct tgtagttgat
     9001 catagatgtt cattttttct ccttatttct caattgttaa atcatagatt gctactactt
     9061 cattctcgga tatttcccca gtttctttaa atccataact gaggtaacaa aatcttgcct
     9121 gttcattttc tggttcataa gacaaccaaa gtttattgct taaacctgct agcgctgttc
     9181 gaacatagtc tagtacttta tccataattg gtttaaaata tccttgattt tgaaaattct
     9241 tatcaatcat aaaacgaaat agtaaataat ttccactact aattccgatc tttttatcat
     9301 aagctatcat cacaaaacct ataattgcat cattatcata aactgccaat ggagctacaa
     9361 aatctccatt tttagtgtag acgtatgctt cagctaaact aattgcgttg gttgcaatga
     9421 attgtttttg atattccttg acatccaaat ttaaaacatc aaaataattt tccattgtaa
     9481 catctcttag ttcaattgtc atagttttgc tccttgttag aggttatcat tggcgcaaaa
     9541 taatgtttac ggcaaactga gatataggtt tcgttaccac caatctggat ctgttctcca
     9601 tcgtaaacgg gcagtccatc ctgtgttcgc aacaccatgg tcgccttttt cttgcaatac
     9661 tgacagatgg tcttgatttc gtcaatcttg tctgctaaaa gcaagagata tttggaacct
     9721 tcgaacaatt cattgcgaaa gtcatttttc aagccaaaag ccatgacggg tatgtctaac
     9781 tcgtccacaa cacgagctag gtcgtaaaca tggtggcgtt taagaaactg ggcttcatcg
     9841 accaaaacac agtaaggttt ttctggtagg tctcggatat agccaaagat atccgttgtt
     9901 tcctcaatcg caagggcagg gcgtttcatg ccaattcgac tcgacacata gccaacaccg
     9961 tcacgcgtat ccagagccga ggtcataatg acaacacctt ttccttgctc ctcgtagtta
    10021 taggccactt tgagaatctc aatcgtttta ccagagttca tggtcccata acgatagtac
    10081 aactgtgcca tgtttcttgc ttcacgtcca tttctaaatt tttgctacat tctagtatat
    10141 cataattttc ttaagcttta aacggcaaaa tgtggtaaaa tggaagaaat caaaactagt
    10201 ggaggaagct attatgccat ttgtacgcat cgatttattt gaaggacgca cgctcgagca
    10261 aaagaaagct cttgctaagg aagtaacgga agcagttgtc cgcaacactg gagcccctca
    10321 atctgctgtc catgtcatca tcaacgacat gccagaagga acttacttcc cacaagggga
    10381 aatgcgtact aaataagcta gcttaagcag aattgcttag gctttttcaa tctccaagta
    10441 gcattcattg aagaaatatc ctaaatttgt tacaatttga aaagaaactt ggagaatttc
    10501 caagaaaata gctattaatt aaaggaaaca ttatgattac acgtgaattt gataccatcg
    10561 ctgctatctc tactccacta ggtgaagggg ctattggtat tgtccgcctg agcggaacag
    10621 acagttttgc tattgcgcaa aagattttta aaggaaaaga cttgaacaag gttgccagcc
    10681 acactctcaa ctacggtcac attattgatc ctctgactgg taaagtcatg gacgaggtta
    10741 tggttggggc tatgaagtct ccaaagacct tcactcgtga ggatattatc gagattaaca
    10801 cccacggtgg tattgcggtg accaatgaga ttctccagct agctatccgt gaaggagctc
    10861 ggttggcaga acctggtgaa tttaccaaac gtgccttttt aaacggtcgc gtagatttga
    10921 cacaggccga ggcggtgatg gatatcatcc gcgccaagac agacaaggcc atgaacatcg
    10981 cggtcaaaca acttgatggt tccctttctg atcttatcaa taatatccgt caagaaatcc
    11041 ttaacacact tgcccaagtt gaggtcaata tcgactatcc tgagtatgac gatgttgagg
    11101 aagccactac tgctgttgtc cgagagaaga caatggagtt tgagcaatta ctaaccaagc
    11161 tccttaggac agcccgtcgt ggtaaaatcc ttcgtgaagg aatttcaaca gctatcatcg
    11221 gacgtcccaa cgttgggaaa tccagccttc tcaacaacct cttgcgtgag gacaaggcta
    11281 tcgtaacaga tatcgctggg acaacacgag atgtcatcga agagtacgtc aacatcaatg
    11341 gtgtacctct caaattgatt gatacagccg gtattcgtga aacagatgac atagtggaac
    11401 aaatcggtgt tgagcgttcg aaaaaagccc tcaaggaagc cgacttggtt ctactagtgc
    11461 taaatgccag tgaaccactg actgcgcaag acagacaact tcttgaaatt agccaagata
    11521 ccaatcgcat tattctactt aataaaaccg acctgccaga aacgattgaa acttcgaaac
    11581 tacctgaaga cgttatccgt atttcagtcc ttaaaaacca aaacatcgac aagattgaag
    11641 agcgaatcaa caacctcttc tttgaaaatg ctggcttggt cgagcaagat gctacctact
    11701 tgtcaaacgc ccgtcacatt tccctgattg aaaaagcagt tgaaagccta caagccgtta
    11761 atcaaggtct tgagctgggg atgccagttg atttacttca agttgacttg actcgtactt
    11821 gggaaatcct cggagaaatc actggggatg ctgctccaga tgaacttatt acccaactct
    11881 ttagccaatt ctgtttagga aaataagaaa aatccatgat ccttcattcg gtcatggatt
    11941 ttattgtctt tattagtaat ctggtcttaa gacccctgtt acagttgcct tagttgcttc
    12001 gtagtcgcca tctacgacaa ccttgataat gcgtttggca tcttcttctg gtgctggaac
    12061 aagaggtaga cgagtgggtc cagcttcaaa tcccatatag ttaagaattg ccttaactgg
    12121 agcaggactt ggataagaga agagagcatt aaccttagga atgaatttac gctgaattgc
    12181 tgcggctttc ttcatatcgc tttctgcaat cgcagtaaac atctcgtgca tttcatcccc
    12241 atttgtatga gaggcaacag aaataacccc atccgcccca aggttcatgg catggaaagc
    12301 atctccatcc tcacctgtat aaatcaagaa ctcttcaggc ttgtgctcaa tcaagtaagc
    12361 catattagcc aagctagtac attctttgac accgataata tttggatggt cagccaagcg
    12421 aagcatggtt tctggagtca attcgacaac tacacgccct ggaatgttat agataataat
    12481 tggtaggtca gaagcatctg caatagtctt aaagtgctga tacatccctt cttgagaagg
    12541 tttgttgtag taaggaacaa tagcaagccc agctgcgaaa ccaccaaatt ccgctacttc
    12601 tttgacaaac tcaatagagt cacgcgtatc attagtacct acacccgcaa tcaaaggaac
    12661 gcgtccattg acaacctttt gtacagccgc aaacaactcc aactcctcat cgtgggtcaa
    12721 agttggactc tcagcagtcg ttcctgcgag aagaattcca tccgtatgat gggccaataa
    12781 atgctcaatc aaggctggaa tagcatcaaa gttaatggaa ccatcctcat ggaagggggt
    12841 aataaaggct gtaatgattt tacatttttt taaatcttga taagacacga aaacacctct
    12901 ctatttcaaa gaaggagttc atctgaactc ctaaacgata tgactatttt aattcaaatt
    12961 tcaattcggc tgttggacga accaatccac gttcatgaag agtttcagca atctgaactg
    13021 agttccaagc agcacctttg agaaggttat ctgaaacaac ccacatgtga attccttttt
    13081 ctgcatccaa gtctttacgg atacgaccaa caaaggtatc acgcgaacca actgcattga
    13141 tagcttgagg atagatttga tgagctacat catcttcaag aacagcacct gggaaggctg
    13201 cgatagctgc ttttacttct tcgattggag ccacttcttt tgtttcgata taaacagact
    13261 cagagtgagc tgacaagact ggaatacgca cacatgttgc agatactgca atgctatcat
    13321 cttccataat tttcttagtt tccttggtca tcttcatctc ttcgtacgtg taatcattat
    13381 cagtgaaaac atcaatttgt ggaagagcgt taaaggcgat aggataatgt ttcttgtcac
    13441 cacctgaagg caaaatttcc gcatgcaaat cacatggttt cacaccatca ttcaagactt
    13501 cacgaagttc acgttgtgtc tcaagaattg ctcccatacc agcacctgaa acggcttgat
    13561 aagttgaaac aatgatacgg tccaagcccc atttttggcg aaccggctca agagccacca
    13621 tcatttggat tgttgaacaa ttagggcagg caatgattcc gttgtgagca tcaagtgcat
    13681 gagcattgac ctctggaaca accaaaggaa catctggatt ttgacggaaa taagatgtat
    13741 tatctactac taccacgcca gcttttactg cgtatggtgc atacttagct gatgtagaac
    13801 tacctgctga aaagagagca atatcaactc cttcaaaagc tgtttcagtc gtttcttcaa
    13861 tcgtaatatc ttgatcttta aatttcaatg acttacctgc tgaacgtgca gaagcaaggt
    13921 aacggatttt atcgattgga agtgttgatt cttccaacat ttttatcatc tgagcaccga
    13981 cggcacctgt cgcgccgact acagcaactg tatatcccat aaataacctc tttcggaatt
    14041 ttctaaaaat ttctataata gaagtattat actacttttt ccatgaattg caaagctttt
    14101 tcatcatttt ttggaaaata aaaatcccag tcgctagact agggactaag aggcatcttc
    14161 atgtgatgag caggttcaca caactcatca aggtccgctc ctgcgttatg acctccttat
    14221 gctcaatagt agtccgaaga ctacctatcg actcatcgca tctactattc tactaaagag
    14281 aatgactttt gtcaacagac gaaactcttt atactcttcg aaaatctctt caaacttcgt
    14341 cagcgtcgcc ttgccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
    14401 aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaagcagt gctttgagca
    14461 acctgcggct agtttcctag tttactcttt gattttcatt gagtattagt tttatttaca
    14521 caggtgcata agaaatatat tggaaaaatt gggggcagac ataacaaaaa cccttgtaaa
    14581 tcaagggctt ttctgtctat ttaatgctaa ttgccgggat tgaaccggcg acctcatcct
    14641 taccatggat gcgctctgcc aactgagcta aatcagctta cttaagaagt atactataat
    14701 cagaaaaact tgtcaagttt ccttagaaat tttccatagg aaaaagccag gtaagaacta
    14761 cctagcttat cttcttctat ttacttaaat caattcgacg accaatttta ccaataataa
    14821 tcgctccaat aatcaatgaa gcaaattcac cgattcctgt tgtaaaccaa gtaaggaaga
    14881 atggtaattc tgctacaata tttaactctg cagcgatagt aaacatggaa attgaaaaga
    14941 ggattgaaaa gaagaaatga tcttttcgaa tcaatccgtt aaagaggtaa tccttgctat
    15001 attttgcaaa aagccaaaca cctaaactga ggaatactaa ggttgaacca ccaccaacaa
    15061 agacatctag cagtccgaag ctaaagaaat tagcaatcat acaaccgatg gtaactccga
    15121 tgatgtactt aggattgtaa aaagccataa agttcatcat ttctgaaata cgaaactgat
    15181 aagcaccata gctgatggca tttaggggcg gtgtgacagt caaaacgacg tagatagcag
    15241 cgacgattgc aatatctgca acatcacgaa tagttaattt tttcatcttt tctcctttgg
    15301 cggttatccg cgtgtaatat gcttggtgaa agaagctaag caccaagggt tgattcattc
    15361 aaccttacta gtatagcaca atagcctgct ttatgctata cttaaagcat gaaaaaacct
    15421 attcaaaaat tttttaacaa tgaaatctta gcctatctct tttttggcct tgcgacaact
    15481 ctagtttcga ttctctcacg actagtcatt tatcaactaa gtcgtcagga actccttgct
    15541 acggccttgg caaatattat cggtatctta tttgccttta tcacaaatga tacgattgca
    15601 tttaagcaaa aaaagaaaaa tagacttatc cgtttagtga aattttctct tgctcgcctt
    15661 tctacttttc tgttagactt gtttttaact tttctctttg taacccaatt tcctcacatc
    15721 atagggcaat tcgtaactga aaacattgat aagataaatg ctattgaaac aataattgca
    15781 caaatattca ttattatcat caattatatc ttgagcaagg tctatatttt tagaaaataa
    15841 tgctccattt atgagccttt taattgcctt ctataatgat ttaggataca atgaaacacg
    15901 aaacattgaa aggaaaacag tatgttaaaa aatctaaaat cgttcttgct tcgaggaaat
    15961 gttattgacc ttgctgtcgg tgttgtcatt gcctctgctt ttggtgctat cgttacttca
    16021 cttgtaaacg acattatcac tcctcttatt ttaaatcccg ctttgaaagc tgctaaagtc
    16081 gaacgtatcg ctcaactttc ttggcatgga gtcggctatg gtaacttttt aagtgctatt
    16141 atcaatttta tctttgtggg taccgccctc ttctttatta tcaagggcat tgaaaaagca
    16201 cagaaactga ctggcataaa gaaagaaaaa actgccgaaa aaaaaccaac cgaattggaa
    16261 gtccttcaag aaataaaagc tctccttgag aaaaaataat cgattaaaag gatctagcgc
    16321 aaagctaaat ccttttttct ttactctttg ggtaacttgc ctgctttttc aagcattttt
    16381 ttgataagat aaggcatctt aacattctcc cgcccttttt tctcaatcag ttttttcaca
    16441 aattctggca tttgtaaatc ttcagattca gctaaaatgt ttttcgtctc gtctgaagga
    16501 actaactcat caaaggtctc ttcttctggg agaaattcct taaactcttg attttcattg
    16561 actctaactg tattgaccaa agcatcaatc aaacgagaat ctgtatttgg cattggtgga
    16621 cgatggtagt ttaccccaaa ttcctggcat aagtcataac attctacatc attgtcaaac
    16681 aagacctcaa tatgctcact gatgaaacta ataggtacaa aaatataatg gtctggatgt
    16741 tctgtctgtt ctctgagata ctccaaaaca tctggtttaa tccatggaat accaatatca
    16801 ctctcactct gccaagtgtt ggtatattgt tctgaactca agcccagttt ttcagcgact
    16861 agcttgctat tttcgaaaat ttggtctata taaggatcac caaagtccaa ggcaaaaatg
    16921 ggcacactat gggctgaaaa gatgacttta cagctgtctt gctttacttc ttcttttaaa
    16981 atcttagcaa tttcatctac ccaatagttt aagagcgctt cttcctgata ccagtcctta
    17041 atgaccaaaa attgaatttg tttgctttct aaaaattttt catagcccat gacagagtag
    17101 aaagaataat ggggctccaa aatcaagcaa atacactgtt caattccgtc tgcttccatt
    17161 tgaccgatca catctggaat aaagggactg gaaaacttat tagcaaagta gacactgtat
    17221 tcattcccca gcctagcttc taccaaggca acctcttgac gggtaatttt ttgcagaggc
    17281 gtgcctccaa ttcgtacata attatcatag agagtctgaa tctcgtggtc ttggggtctc
    17341 accccacgac gaatatttgt gaaaaaatca gctacacctt caaaggtaat ctcttctggt
    17401 gaaccgaagg tcatcattaa aattgctttt ttcatgactg cttccttgtg atgtttttat
    17461 caagtttatt ttatcattaa ttcatcgata agtaaacgct aacataggga cattctcaat
    17521 cttctgtctt ttgtttttct cttctttcta tgatacaatg gaaaaaataa attcaaaagg
    17581 agttttttat gacttatcca aatctcttgg accgcttctt aacctatgtt aaggtcaaca
    17641 cgcgctctga tgaacactct actactactc caagtacaca gagtcaggtt gacttcgcaa
    17701 caaatgtcct aattcctgaa atgaaacgtg ttggactgca aaatgtttac tatctaccga
    17761 atggttttgc tattggaacc ttgccagcca acgatccgtc tttaacacgt aagattggtt
    17821 ttatatcgca catggatact gctgatttta atgctgaagg agtcaatcca caggtaattg
    17881 aaaactacga tggtggtgtg attgaactag ggaattctgg tttcaaactc gatccagctg
    17941 acttcaagag tcttgaaaaa tatccaggac aaacgctcat cacaacagat ggaacaacct
    18001 tgctaggtgc tgatgacaag tcaggaattg ctgaaattat gacagccatt gaatatctaa
    18061 ctgctcatcc tgaaattaag cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa
    18121 tcggtgttgg tgccaataaa tttgatgcag aagattttga tgtggatttt gcctacactg
    18181 ttgatggtgg tccactaggt gaacttcagt acgagacttt ctcagccgct ggtgctgaat
    18241 tgcatttcca aggccgtaat gtccaccctg gtactgccaa agggcagatg gtcaatgccc
    18301 ttcagctagc aattgatttt cataatcaac ttccagaaaa tgaccgacct gagttaactg
    18361 aaggttacca aggtttttac catctaatgg atgtgacagg tagtgttgag gaggcgcgtg
    18421 caagctacat cattcgtgat tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc
    18481 aatctatcgc tgataagatg aatgaagaac ttgggagcaa ccgtgtcact ctcaacttga
    18541 cagaccagta ctacaatatg aaagaagtca ttgaaaaaga tatgactcca attaccgttg
    18601 ctaaagccgt tatggaagat ctaggtatca cgcctattat cgaaccaatc cggggtggaa
    18661 cagacggctc taagatttcc tttatgggaa tcccaactcc gaatatcttt gcaggtggcg
    18721 aaaatatgca cggacgtttt gaatacgtta gccttcagac tatggaacgt gcagttgata
    18781 ccatcattgg catcgtagct tataaaggct aaaaagacga ggtggctcag ctacttcgcc
    18841 tttcttttta ttctactggt ttttcttgat ttccagtagt tgtagaagat tctgttgttt
    18901 tattttctga agttgattca gcaggtttag aatctcttgt attgcttggt ttgttttcgt
    18961 cgctagcagt ttcaatgtta gattctgcag ttgcgtttgg ttggttctca gcactggtgt
    19021 tatcaccatt tgcttcagca tttcttgctg gacttgtttc ttcacttgcg ctagcttttg
    19081 actggatttg atgattcaaa actagaatag cttttgtcga ttcaagtaaa gctgttttgt
    19141 ctttactatt agcagaaagt tgatctaata atgcatccac cttatcaaag tccgcatcag
    19201 atccattatt actttctaag cgacatgaga atatcgtaga gtttttgata gagtacaagt
    19261 gtctgagaat cttgctcagc attttccttt tcttgttgaa gggcgctagc gatacgagtc
    19321 aaaacatctt ttacctgact gtttacttca tccaagtctg catcaacctt gtttgtggca
    19381 gcttttagat tttctacttc ttctgccaag gattgtctga ttccttcttc atggatttgt
    19441 tccaagagtt gatttgcctt gctcaaaaga ctttctactt cttccttgct atctgtcgca
    19501 gattattggt tgctatctac catgtactcc taaaacagga gagttataat ccaagattac
    19561 aaggccttac agaaataaga aatccagata agacaatgtt cgtccaagac gctattcgct
    19621 tcgcacaaca gcacggattc aatatgcttt aattttaaag tttaggtgtc aagacctctt
    19681 tttagtgtgc ccaaaattta gagaagtaat caatcaacta acttttattt ttttcaaact
    19741 ttcagtaaac tgacctaaag ctaactcaat ctgtctttgt agatgcttct gctatcagct
    19801 agaagttgat ctacttttgc caagactgcc ttctcatcaa aagttccagg ttgatagttg
    19861 gattgcaggg atggaatctt gtttttcaaa gccgcttcat atcccttagt ttgaaccttg
    19921 atgtagtgat tgtggtcgcc atgaggaatc acaaaacctt ctgaatcttc acttataatt
    19981 cgattggcat caaaaccatg accatcttct tcctcatggt ggacatgtag tgacggatta
    20041 cttaatacag aactagaaga acttcctgcc tcttccgtgt tagagtgtga tgggggattg
    20101 ttaagagatg acttaggaat ataatgatag tgatccccgt gtcttactat ataagcatca
    20161 cctgtatctc tgacaatatc attagggtta aagacataac catcatctgc tgcagaaaca
    20221 ccattattcg gtgtcaccga caaagattga ctgagagctg tagtattccc tgataattat
    20281 acttttgcag ctgctaattc acctgccgac aagtcactct caggaatgaa atgatagtga
    20341 ccaccatgtg gtactatagt aggttgaaat agaatatgag caaattgata aggggatttt
    20401 aaagtaattt ctaacaatga tttagaaact atgatgtgct attctaaatt caactcacta
    20461 tatataacca tcatcggtag tataacgtcc ctgtaatttt gctacagata cttctgcact
    20521 agctccttta tcgtctttac catgttcttg tttttggcga ttgatttcat cttttgttcg
    20581 tacattttct gcatgagctt gatctttaag gtaaacataa tactttccat ctaccttaat
    20641 aatatatcct cccttaacct aactgacgat atcttgatct ttcggctgat agttgggggc
    20701 tttcattaat agctcttcac taaagagcgc atcaaaagga actttaccat tatagtagcg
    20761 ataatgatcg ccatgagaag ttacataacc ttgatctgta atcttaataa caatttgttt
    20821 tgcttgaatt ccttcttttt gactaaccta gtctggagtc aaattttcag tcttcttagt
    20881 gtctttatta ctgtttacat atgaaacacg atttttatct gtattggcct gttagctatg
    20941 ttggttcaga gtataaacac acagacttaa ggaaaggata acaacagatc cagctgctat
    21001 atatttcttt ttaaatttca taattacctc atttctataa ttatttatat gatgtcttca
    21061 ttattaaatg attaaataaa ttaattaacc aattaattaa ctagtaaata ttccacctct
    21121 ttttaagttg tatgtcaaga aattttatat attaataata aaatgaaatt ctcccaaagt
    21181 cagagtttta tttctaactt ttgagagaac ttcatttttg attcagactt tttctactgc
    21241 tattccttac gctatgaaat cagataaatt cttttttatc acttctccac ttggcaatct
    21301 taattcaatc gttccatcca tattgaatat aacactatct aagcctaatc cgtaactagc
    21361 tgtaaatttt tctaattttt cttgtacagg atctactgct ggagcttcct ctaatgctgg
    21421 atctaacata gggtcactcc ccacattccc ttctggattc aacattccat tatccgttga
    21481 gttttctggt tttacaggtt tttcgtttgg tgcctctggt aaagaatctg ctggtttatt
    21541 ttctgttggt tggttctcaa ctgttccagt agatactttt ccattttcag atggtttatt
    21601 ttcaccattt ccttgaggtg cttctcctgt aaaatctgcc atattctttt taatgacttc
    21661 tcctgatggt aaatataatt caattgttcc gtccatatta aacaagacat tttctagctt
    21721 catcccataa ctttcagcaa attttgctac tttttcttgt acaggatcca ctgtaggaac
    21781 ttcttctaac gttgaattac tagtactatt cccagtttca gaaagttttt ctttttctac
    21841 cttctcacta gtctttggtt cttctacctt ttcatcaagt tttgagtttt cttgtgcttt
    21901 attcctttta aattgtggta gaatacttgg tttatcagtt tgattttctt tttccaagat
    21961 aggtacttcc acaatataag tcgattgatt gtccaaataa gcatttgcca tgaaggttac
    22021 aggaatttta tttccggccg ttctggttgt tccttggttt aatttcggaa tcggtaattt
    22081 gatttcacca actttatagt tattttctaa ataagcattt ccatgaaatt catcaaacac
    22141 tctgactaaa gcatcagttc ctttaggcac tgcaaattga gggttcactc ttaaataagt
    22201 atcccctgca tggaaaggat agaaaatcgt ttgactggcc attttgtaag ctaaagaggt
    22261 tggaactgta aatgtaccat cataacttac ttctggataa tcttttgaag cgatagtata
    22321 cttaaatgtt tgtcctggta aataaggttg atctaattca aagtttgcaa tattccctac
    22381 tccttctcca aatactttac cagatacttt ctccaatact tttccatctg gtgttattaa
    22441 ttttactagc atattgatac ctaatttttt ctccaattca ggcggaaaac taaaagaaac
    22501 gcgtttttga ccattggcta gagtaaagtt ttgattatta aacgtactat tttttaacaa
    22561 attaacaaca ttcgttaatt cttctccagt ataaacttta ttcccttctt ttttagcaac
    22621 tccttcttcg ggtttaaaca gttcatagtt actgtgagaa tgaccaattc caaccggttt
    22681 atgttcatca atcggatctg catgatggtg atctccatgc ggataaataa tcgcattttt
    22741 ttctttattc acgacaatac tttcacgttt gacaccatat tgtttcataa tgccagcaat
    22801 tttttcttcg atttttttat ctaaatcttt catttctttg gcattacctg gataatcctg
    22861 ttcatgagat gacaaagaat ctaatccatt atgactagtt ttaacttcct ctaaatgttt
    22921 ttgcgcagcc ttaatttgct cttctgtcaa gtccttcttg aagaaataat gattgtggtc
    22981 tccgtgactc atgacaaaac ctgattcatc ttcagcgata atacgattag catcaaatcc
    23041 gtatccatct tcttcatgtt tctcatgtga agttcctgga ttgattggaa gagatggaga
    23101 aggtgttgct agactattgt ttggaagagt cggttgccca atttgatttg attttggaat
    23161 gtaatggaaa tgatcaccat gtcttacaat ataagctgta gccgtttctt caacgatatc
    23221 ttttggatta aaaatataac catcagatgc tgaagagagc tccttacttg tcgttaaaga
    23281 agaaggattg cttgaaagac tgcctagact agacactact tcattaggtt ttgcatttgt
    23341 agaaactgta gaaccagttc cactgatagg caccattctg gcaatttttt cttctaaagc
    23401 agaaagcttg ctgtaaggaa taaagtggta atggtcgcca tgcggaatcg caactccatt
    23461 tggtgtacga ctgataatct tagcagggtc aaagaccagg ccatctgatt cactgtaacg
    23521 ttgggcgcta ggtgaatcat agagttcctt caaaagactc tggagatttt cagatttatt
    23581 tgctggcttg ctagttgatc cttttgctac agattgcgtg ttattgtcac tagctgttga
    23641 agaatagctt aactgactcg gttgcatatt ttttccagcc agatgtgctt tagctgctgc
    23701 taattcacta gcagataaat cgcttttggg aatgtagtga tagtgacctc catgaggaac
    23761 gatataagca ttacccgtat cttcgataat atcagctgga ttaaagacat aaccatcatt
    23821 tgtcgtatat cgtccctgag accttgctac agcaacatta gagttaacct tctcattatc
    23881 tttgacatgt tcttgttttt gacgattgat ttcatcttta gttcgaacat tatcagcatg
    23941 agctgcatct ttcaggtaga cataatattt tccatcgacc ttgatgatat aaccaccctt
    24001 gacttcattg acaatatcag cgtctttaag ttgatagttt ggatccttca tcaagagttc
    24061 ttcactaaag agggcatcat aaggaacttt cccattatag taatgatagt ggtcaccgtg
    24121 tgacgttaca tagccctgat ctgtaatttt gattacaatt tgctcagcct gaattccttc
    24181 tttctggcta acctggtctg gtgtcaagtt ttcacttttc tgacttgact ggctgccatc
    24241 cacataagag acacgattat tgtccttatt ttcctgcgaa cgatgctggt ttagtgcata
    24301 ggcacataga ctcaaggata cgataacagc tgatccagct gctatatatt ttttactaaa
    24361 tttcataaat ccctcatttc aataaatgat gaagtttttt tctcaacttc ttttacttta
    24421 ttaaatagtt ttctaaaccg attatttaac catttaatta accagtaaat agtctactat
    24481 ttaaaattac ttttgtcaag tttctgttac gtttttctaa aaaagagaag taacacgaaa
    24541 ggttacttct ccataaaata tgctccattc attttactac tgtataggag ccggttgact
    24601 ttcttttaac aaagccaaga gactatctac ttctgctgaa atagtattat tatctttcgt
    24661 tccgagaaga agactacttt ttagaccagt caatgtctcc atagcatttt gtctaatact
    24721 agaatctgtt actttttcta gcaaggcctc cgcctctgct atcttagcgt taataacaga
    24781 atgctctact tgaggaattt cagcctcatc tgtagtatct tcagcttctt cctctgtctc
    24841 ttccgtatca gtgcttggtt tataaagatt atctgctgaa ggatttaaac cagcgtgatt
    24901 ctctttttca tcagattcag ggtgagttgg ctcacttact tcatcatgtt ccttatcttc
    24961 ctcaggtttt tctgtctgag gtttctccgt ttgattggta tcagcttgac catttttgtt
    25021 tctttgaaca tggtcgctag cgttaccaaa accattatct gaatgcggac gttcgtttgg
    25081 atgttcgaca tagtacttga cagtcgccaa aagatcctca agagtatacc ccttaggtgc
    25141 ctcataaagg ccttcgtcaa accactcaaa tttgatgtta tggtaatggt cataatgagg
    25201 tatgattaaa ctaccgtttt tgacttctac agtatattga agattgtaag gcatacgatc
    25261 aagtggcacc ttcttagctg ctttcacgcg gttgtagata gcttctgctc cttttgcctc
    25321 agtatttcct gaatcctgat ggtctgtcga aggaggggtc aaacctttct ctttagcata
    25381 agcctgggct gccgctctct cagcttcaga caaactatct tttttaatcc agtggctatg
    25441 ggtcatatgt ggagttacat aggcatcccc ctcatcactg gttatatcac gaggatcaaa
    25501 gatataaccg tcttctgttg tgtacttgcc tgccaacttg gctacttgaa tctcatcatc
    25561 agtgtaggta atttgcgaat ttggttttcc taaacgttct ggatgacgaa tcggagctaa
    25621 gaaggcaaga atatcatcca ctaacttgac tttatcactt gagacatcct tgagtcgttc
    25681 caacaggtta tccaaagcct caaaatcaac ttgtcgacct ttattatcaa gtaaatcttg
    25741 gtgaattctt gctagtaagt cataagcctt attgtaaaat tctctatcac tagatgggag
    25801 gtcagttttc ttagctccta gcttatgaga taaactttcc tgcttggcca gtttgcta
//
LOCUS       DAVLHB010000028        25171 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLHB010000028 DAVLHB010000000
VERSION     DAVLHB010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25171
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.028"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..622
                     /locus_tag="VXE36_001284"
     CDS             <1..622
                     /locus_tag="VXE36_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0779588.1"
                     /translation="IGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAA
                     LALSTPIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFT
                     LGCLGALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLG
                     YVCAAYLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            609..1427
                     /locus_tag="VXE36_001285"
     CDS             609..1427
                     /locus_tag="VXE36_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0779589.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            1427..1720
                     /gene="yajC"
                     /locus_tag="VXE36_001286"
     CDS             1427..1720
                     /gene="yajC"
                     /locus_tag="VXE36_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0779590.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHYIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            1742..3643
                     /locus_tag="VXE36_001287"
     CDS             1742..3643
                     /locus_tag="VXE36_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0779591.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVCKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNQEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEVLTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            3703..4704
                     /locus_tag="VXE36_001288"
     CDS             3703..4704
                     /locus_tag="VXE36_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0779592.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(4814..5149)
                     /locus_tag="VXE36_001289"
     CDS             complement(4814..5149)
                     /locus_tag="VXE36_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779593.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLTYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(5160..5402)
                     /locus_tag="VXE36_001290"
     CDS             complement(5160..5402)
                     /locus_tag="VXE36_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779594.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(5413..5955)
                     /locus_tag="VXE36_001291"
     CDS             complement(5413..5955)
                     /locus_tag="VXE36_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0779595.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIRNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(5971..6165)
                     /locus_tag="VXE36_001292"
     CDS             complement(5971..6165)
                     /locus_tag="VXE36_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0779596.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            6331..7281
                     /gene="rsmH"
                     /locus_tag="VXE36_001293"
     CDS             6331..7281
                     /gene="rsmH"
                     /locus_tag="VXE36_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0779597.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            7293..7610
                     /gene="ftsL"
                     /locus_tag="VXE36_001294"
     CDS             7293..7610
                     /gene="ftsL"
                     /locus_tag="VXE36_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0779598.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            7614..9866
                     /gene="pbpX"
                     /locus_tag="VXE36_001295"
     CDS             7614..9866
                     /gene="pbpX"
                     /locus_tag="VXE36_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0779599.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSIFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            9868..10848
                     /locus_tag="VXE36_001296"
     CDS             9868..10848
                     /locus_tag="VXE36_001296"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0779600.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            11457..13562
                     /locus_tag="VXE36_001297"
     CDS             11457..13562
                     /locus_tag="VXE36_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0779601.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKV"
     gene            complement(13858..14340)
                     /locus_tag="VXE36_001298"
     CDS             complement(13858..14340)
                     /locus_tag="VXE36_001298"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0779602.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(14435..15919)
                     /locus_tag="VXE36_001299"
     CDS             complement(14435..15919)
                     /locus_tag="VXE36_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0779603.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDESAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGKIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            16072..17682
                     /locus_tag="VXE36_001300"
     CDS             16072..17682
                     /locus_tag="VXE36_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0779604.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLNYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVEMTD"
     gene            complement(17813..19243)
                     /locus_tag="VXE36_001301"
                     /pseudo
     CDS             complement(17813..19243)
                     /locus_tag="VXE36_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398391.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            19399..20844
                     /gene="cps4A"
                     /locus_tag="VXE36_001302"
     CDS             19399..20844
                     /gene="cps4A"
                     /locus_tag="VXE36_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0779605.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFIKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKRILLTTTPRDSYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            20846..21577
                     /locus_tag="VXE36_001303"
     CDS             20846..21577
                     /locus_tag="VXE36_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0779606.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            21586..22278
                     /gene="cpsC"
                     /locus_tag="VXE36_001304"
     CDS             21586..22278
                     /gene="cpsC"
                     /locus_tag="VXE36_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV0779607.1"
                     /translation="MKEHNTLEIDILQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGTYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNILIGFLAGGVGTGVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            22288..22971
                     /gene="cpsD"
                     /locus_tag="VXE36_001305"
     CDS             22288..22971
                     /gene="cpsD"
                     /locus_tag="VXE36_001305"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEV0779608.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVILNKFDVQHKKYGSY
                     GDYGNYGKK"
     gene            22987..24354
                     /locus_tag="VXE36_001306"
     CDS             22987..24354
                     /locus_tag="VXE36_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0779609.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGHLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLVL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKMDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFI
                     RDGAK"
     gene            24358..24807
                     /locus_tag="VXE36_001307"
     CDS             24358..24807
                     /locus_tag="VXE36_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--LPS N-acetylglucosamine
                     transferase"
                     /protein_id="HEV0779610.1"
                     /translation="MKVCLVGSSGGHLTHLYLLKPFWNDKERFWVTFDKADARSVLSE
                     EVVYPCYYPTNRNIKNLIKNTFLAYKILKKERPDLIISSGAAIAVPFFYIGKLFGSKT
                     VYIEVFDRIDASTLTGKLVYPVTDRFIVQWEEMKKVYPKAINLGGIF"
     gene            24807..>25171
                     /locus_tag="VXE36_001308"
     CDS             24807..>25171
                     /locus_tag="VXE36_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug MFS transporter"
                     /protein_id="HEV0779611.1"
                     /translation="MIFVTVGTHEQQFDRLIKEVDYLKKENLIQDEVFIQIGYSSYIP
                     KYCEWEKIISYEKMNQLIKESDIIITHGGPATFMGVIAKGKVPIVVPRQKKFGEHVND
                     HQLQFVKLTKEIYNFIVID"
BASE COUNT         7593 a         4335 c         5614 g         7629 t
ORIGIN      
        1 tattggtgaa ttggcttata tgggattcgg tgttggtgct ggaggtactg ttccaccaaa
       61 cccaatcgga cctggtatct ttggtacctt gatggctatc actagtgctg gtaaagtcag
      121 tccagaagcg gctcttgccc tctctactcc gattgctgtg gcgattcaat tcttacaaac
      181 tttcgcctac actgtacgtg ctggtgcgcc tgaaacggcg atgaagcact tgaaaaacca
      241 taatttgaag aaattcaagt tcactctaaa tgcaacaatt tggttgtttg cctttattgg
      301 atttaccttg ggttgcttgg gtgccctttc aatggatacc ttgttgaaac tcgtagacta
      361 cattccaccg gtattactta caggtttgac agttgctggt aaaatgctcc cagctatcgg
      421 ttttgcgatg atcttgtcag tgatggctaa gaaagagttg attccctttg tcttgttggg
      481 atatgtttgt gcagcttatc taaacatccc aacaattggt attgcaattg taggtactat
      541 ctttgctttg attgaatttt ataacaagcc aaaaacagcg gatcatgtgg tagaggagga
      601 agcacacgat gactggatct aacaaattaa caaaacgtga ttatcttaaa acgtctttgc
      661 gggcattctt ttgtcaaaat ggatttaact atagtaacta tcaagggttg ggatatgcca
      721 atgtgatgta tcctgctttg aaaaaacact atggagagga tcaggaaggt ttctaccaag
      781 ccttggaaga aaactgtgaa ttctataata ccaacccaca cttcctgcct tttattacca
      841 gcttgcatct tgtaatgttg gaaaatggtc gaccaacaaa agaaacacgt agcatcaaga
      901 tggccttgat gggaccattg gcaggtattg gggattctct ttctcaattc tgtttagctc
      961 cattgttctc aaccatcgca gcttcgtttg ctcaagaagg cttggttgtc ggtccaatct
     1021 tgttcttcct tgcgatgaat acgattttaa cagcgattaa attgtcaact ggtctgtatg
     1081 gatacaaact aggaacaact gtgattgata aactaagcga gcagatggca acgatttctc
     1141 gtattgccaa tattatcggt gtaaccgtaa ttgctggttt ggcagcgaca tctgttaaga
     1201 ttatggtgcc gattaccttt gctgcagggg aagttaaagc agacgctaaa caaagtatcg
     1261 taagtattca gggaatgctt gataaggttg ctccagctct tctaccagcc ctatttacac
     1321 ttttagttta ctacttgatc aaagaaaaga aatggacaac atataaactc gttattttaa
     1381 cagttatcat cggaattatc ggaagctggc ttaagattat agcttaatgg atacaacatt
     1441 gttttatgga atagtgattg tcttggcagt gagtcccctt ttactgtcaa gctttcatta
     1501 tattcgtcag caaaagttgc ttcgcaaaca gatggagcaa cgacaagagt atttagcttc
     1561 tttaacatct ggtgatgaag tgttgttatt gtctggaatt catggaaaaa tcatttctat
     1621 ccaagatgac ttggtctcct tgcagattgc aaaaggtgtg gtcatctatg tagaaaagga
     1681 aagtgtaatg ggaaagacaa aagaactgct ttttaagtag ttctttttct ggtaatagat
     1741 aatgaaagaa gaaagaagac aattttttga aagaatcgat ggaaaccaat gtcgtgatta
     1801 tatcttgtcc cactgttcaa aagactatga gaaagtcaag agttcccttg aacgcttgat
     1861 ggacaatcgt tttatgtttg atagtccttg ggatatggag ccttgttcaa aaatccatca
     1921 aatccagccg atggtatggg atcaagtatt tgaagatgat ccagaatggg cttatatgct
     1981 caatcgacaa gaatatctct tgcagtttat gatagggtat gtggtagaag gagataagag
     2041 ctatattcaa aagtgcaagt tctttctatt tgattggatt gagcaggtga gagaattttc
     2101 tcctcaatcc ttgatgacta gaaccttgga tacgggtatt cgttccttta cttggttgaa
     2161 actactcttg cttctcttga aatttgactt gctagaggag aaagaactag agaaaatttt
     2221 ggtcagtcta gaaaagcaga ttgactttat gaaaagctac tatcgcgcca agtacaccct
     2281 tagtaactgg gggattttac aaacaattcc gatgcttgct atctatcatt tcttttcaga
     2341 taagatggat ctagaagaag cttaccattt tgcttcagag gagttgaaac agcaaattga
     2401 gacacagatt ttaggagatg gaagccagtt tgaacagtcg attctctatc atgtagaggt
     2461 ttgtaaagcc ttgctggatt tgtgtctctt gcttccagac ttgcaagata gttaccaaga
     2521 gttgctggaa aagatggcga cctatattca aatgatgaca ggcttagatg gacggacttt
     2581 ggcttttggt gatagcgatt ctacagaaac gacagaaatg ttgagcctgt ctgctgtggt
     2641 tttgaaccag gaagaccttc ttaacggtct ggatgttaaa gttgatttgc ttagcctctt
     2701 gttcctgggg cgagaaaagg tcaagcgact gcaggaattt gaaaagagag cttggcagcc
     2761 taagtccatg atctttgaag actctggaca tgtctgcatt aaggatgaac atcgttatct
     2821 atttttcaaa aatggtccgc taggaagtgc ccatagtcat agtgacgaga atagtttttg
     2881 cttacagtat caaggccaac ctattttcat agatgctggg cgttattctt atcgggagat
     2941 atatgaacgt tatctcttaa agagtgcttg gagtcattcg acctgcattg tagatgggaa
     3001 agctccggaa agaatcacgg gatcctggga atatgaatac tatcctcact ccctgttttg
     3061 tcaccataaa gaaagggagg gagtgcatta tattgagggg gcttattggt cagcagaacc
     3121 tgatttgcct tatcttcaca ggagaaaaat cctcatgttg gtagaggatg tctggctctt
     3181 ggtagatgac atcaggtgtc aaggtcaaca tgaggtgttg actcagttta tccttgacaa
     3241 ggatgtgacc tatcaagatg ggaaaatcaa tcagttgaga ctatggagtg aagttgattt
     3301 tgatttggaa gataccatca tttctcctaa atacaatgag cttgaaagaa gtagcaaact
     3361 caccaagcgc caattctttg agaatcagat gctggattat accatcattg cgcatgagag
     3421 ttttgaaatc atccgtcatt ctgtctacca gacagatgat cgtgaagtgg aaaatgctct
     3481 ggcttttgaa gtgaaaaatg atgaaacaga caagctgatt ctgttattaa gcgaggatat
     3541 tggtgtaggt gaaaaattgt gcctcgttga cggaacaaaa atgcgtggaa aatgtttagt
     3601 atatgataaa ataaatgaga gaatgattcg cttgcagtgc tagaaatagg cattttgaat
     3661 agtgaatatg ttataataag tattagtagg aggtgtttta gattggagaa gaaactgacc
     3721 ataaaagaca ttgcggaaat ggctcagacc tcgaaaacaa ccgtgtcatt ttacctaaac
     3781 gggaaatatg aaaaaatgtc ccaagagaca cgtgaaaaga ttgaaaaagt tattcatgaa
     3841 acaaattaca aaccgagcat tgttgcgcgt agcttaaact ccaaacgaac aaaattaatc
     3901 ggtgttttga ttggtgatat taccaacagt ttctcaaacc aaattgttaa gggaattgag
     3961 gatatcgcca gccagaatgg ctaccaggta atgataggaa atagtaatta cagccaagag
     4021 agtgaggacc ggtatattga aagcatgctt ctcttgggag tagacggctt tattattcag
     4081 ccgacctcta atttccgaaa atattctcgt atcatcgatg agaaaaagaa gaaaatggtc
     4141 ttttttgata gtcagctcta tgaacaccgg actagctggg ttaaaaccaa taactatgat
     4201 gccgtttatg acatgaccca gtcctgtatc gaaaaaggtt atgaacattt tctcttgatt
     4261 acagcggata cgagtcgttt gagtactcgg attgagcggg caagtggttt tgtggatgct
     4321 ttaacagatg ctaatatgcg tcacgccagt ctaaccattg aagataagca tacgaatttg
     4381 gaacaaatta aggaattttt acaaaaagaa atcgatcccg atgaaaaaac tctggtattt
     4441 atccctaact gttgggccct acctctagtc tttaccgtta tcaaagagtt gaattataac
     4501 ttgccacaag ttgggttgat tggttttgac aatacggagt ggacttgctt ttcttctcca
     4561 agtgtttcga cgctggttca gccctccttt gaggaaggac aacaggctac aaagattttg
     4621 attgatcaga ttgaaggccg caatcaagaa gaaaggcaac aagtcttgga ttgtagtgtg
     4681 aattggaaag agtcgacttt ctaaaatgaa ggaaaatgac ttgcaatttc tgttaagaaa
     4741 taaaataatc ccacctagaa caagctaggt gggattattt gcctatgaaa tgagaaatta
     4801 tgggagcaag ctcctaaatc aactgttttt gatctacttc tttaactact tgataaaagt
     4861 tatagaagta ggtcaaactt gaaatgatgg ttacgactag gaatattgaa aatttccatt
     4921 ggacagggtt ggttaaaagt tgtggaaagg atatgaggag aaagaagagg gctgcgttga
     4981 ggacaggtat ccgttttgat tgtattttct caagtccttt attgagcgca ggaagaaaga
     5041 ggagtaggag tagtaaaact gtatgagaaa cagctcctga aataagggcg aagaaaagga
     5101 aaatactgat aaaaacatga atgatcagta gtctagctag tgatttcata aggcacctcc
     5161 taatcctggt cttttttagc tcttgcaata cgaagtgagt cgacaatatg tatcatcact
     5221 ccgaaaaaga aagctcccag tatagtttta aaaatatgtt ttgtatttag aagagaactg
     5281 ataaaatttg gattttcact tgttagggta tcaatgagtg gaattataaa aaatatcact
     5341 gttccataaa tcgaacctgc tttcagacct ggataacgta actgtctctt ttcttttttc
     5401 atagggcacc tcctaatcct catcttgatt tttcttagtt tttgcaatgc gacgggagat
     5461 gaggaactgt atgctcgctc cgaagaaaat agaaccgaga atgcttgata caccatttct
     5521 tatagtgaga agagaatgaa aatagtcctg accttcacct atgagtatcc tgagaagagg
     5581 agttataaaa aacatccata gaccaaagaa caaacctgct ttcagacctg ggtagtgtag
     5641 ttgcttgctt tctttctcat tcagcatatc tggttcaatg actgtgatgc ctgttttttt
     5701 catttggtag gtgacatagc cagcagcgat gagggcaatc actaaaatca gaggaggata
     5761 gattagagcc acttcttgag ggtatttata ggccagaagg agtggaataa gatttccgaa
     5821 aatcatcaga taaaagagga cgataaaaac ttggttccga atactatcgg cctcacgccg
     5881 tttgtattcg tcaaggggac cagaaatacc gtatgtgcgt ttgatcagtt tttcagtgaa
     5941 ggtttctttt ttcataagtt tgctcctttt ttaaaaatct tcctcccaaa agagactgtt
     6001 gaggtcagtt tggaggctgc gggcgagatt gagacagagt tccaaggttg gattgtactt
     6061 gtcgttttca atcatattga tagtctgtct cgagacaccg atatccttgg cgagttcgag
     6121 ctgggaaata cccaattcct tgcgaaattc tttcacacga ttcatctgtt ctcctttctg
     6181 atttatgtcg tatatatttg actatattat agtcttttaa acataaagtg tcaagtattt
     6241 ttgacatatt ttttgaagaa atagtagtct ccttgtccta tttgtctgac aagtgcaagc
     6301 tggtcggatt tgtggtaaaa tagataagat atgacaaaag aatttcatca tgtaacggtc
     6361 ttactccacg aaacgattga tatgcttgac gtaaagcctg acggtatcta cgttgatgcg
     6421 actttgggcg gagcaggcca tagcgagtat ttattaagta aattaagtga aaaaggccat
     6481 ctctatgcct ttgaccagga tcagaatgcc attgacaatg cgcaaaaacg cttggcacct
     6541 tacattgaga agggaatggt gacctttatc aaggataact tccgtcattt acaggcacgt
     6601 ttgcgcgaag ctggtgttca ggaaattgat ggaatttgtt atgacttggg agtgtctagt
     6661 cctcaattgg accagcgtga gcgtggtttt tcttataaaa aggatgcgcc actggacatg
     6721 cggatgaatc aggatgctag tctgacagcc tatgaagtgg ttaatcatta tgactatcat
     6781 gacttggttc gtattttctt caaatacggt gaggataaat tctctaaaca gattgcgcgt
     6841 aagattgagc aagcgcgtga agtgaagccg attgagacaa cgactgagtt agcagagatt
     6901 atcaagttgg tcaaacctgc caaggaactc aagaagaagg gtcatcctgc taagcagatt
     6961 ttccaggcta ttcgaattga agtcaatgat gaactggggg cggcagatga gtccatccag
     7021 caggctatgg atatgttggc tctggatggt agaatttcag tgattacctt tcattcctta
     7081 gaagaccgct tgaccaagca attgttcaag gaagcttcaa cagttgaagt tccaaaaggc
     7141 ttgcctttca tcccagatga tctcaagccc aagatggaat tggtgtcccg taagccaatc
     7201 ttgccaagtg cggaagagtt agaagccaat aaccgctcgc actcagccaa gttgcgcgtg
     7261 gccagaaaaa ttcacaagta agagggaaaa agatggcaga aaaaatggaa aaaacaggtc
     7321 aaatactaca gatgcaactt aaacggtttt cgcgtgtgga aaaagctttt tacttttcca
     7381 ttgctgtaac cactcttatt gtagccatta gtattatttt tatgcagacc aagctcttgc
     7441 aagtgcagaa tgatttgaca aaaatcaatg cgcagataga ggaaaagaag accgaattgg
     7501 acgatgccaa gcaagaggtc aatgaactat tacgtgcaga acgtttgaaa gaaattgcca
     7561 attcacacga tttgcaatta aacaatgaaa atattagaat agcggagtaa gatatgaagt
     7621 ggacaaaaag agtaatccgt tatgcgacca aaaatcggaa atcgccggct gaaaacagac
     7681 gcagagttgg aaaaagtctg agtttattat ctatctttgt ttttgccatt tttttagtca
     7741 attttgcggt cattattggg acaggcactc gctttggaac agatttagcg aaggaagcta
     7801 agaaggttca tcaaaccacc cgtacagttc ctgccaaacg tgggactatt tatgaccgaa
     7861 atggagtccc gattgctgag gatgcaacct cctataatgt ctatgcggtc attgatgaga
     7921 actataagtc agcaacgggt aagattcttt acgtagaaaa aacacaattt aacaaggttg
     7981 cagaggtctt tcataagtat ctggacatgg aagaatccta tgtaagagag caactctcgc
     8041 aacctaatct caagcaagtt tcctttggag caaagggaaa tgggattacc tatgccaata
     8101 tgatgtctat caaaaaagaa ttggaagctg cagaggtcaa ggggattgat tttacaacca
     8161 gtcccaatcg tagttaccca aacggacaat ttgcttctag ttttatcggt ctagctcagc
     8221 tccatgaaaa tgaagatgga agcaagagct tgctgggaac ctctggaatg gagagttcct
     8281 tgaacagtat tcttgcaggg acagacggca ttattaccta tgaaaaggat cgtctgggta
     8341 atattgtacc cggaacagaa caagtttccc aacgaacgat ggacggtaag gatgtttata
     8401 caaccatttc cagccccctc cagtccttta tggaaaccca gatggatgct tttcaagaga
     8461 aggtaaaagg aaagtacatg acagcgactt tggtcagtgc taaaacaggg gaaattctgg
     8521 caacaacgca acgaccgacc tttgatgcag atacaaaaga aggcattaca gaggactttg
     8581 tttggcgtga tatcctttac caaagtaact atgagccagg ttccactatg aaagtgatga
     8641 tgttggctgc tgctattgat aataatacct ttccaggagg agaagtcttt aatagtagtg
     8701 agttaaaaat tgcagatgcc acgattcgag attgggacgt taatgaagga ttgactggtg
     8761 gcagaatgat gactttttct caaggttttg cacactcaag taacgttggg atgactctcc
     8821 ttgagcaaaa gatgggagat gctacctggc ttgattatct taatcgtttt aaatttggag
     8881 ttccgacccg tttcggtttg acggatgagt atgctggtca gcttcctgcg gataatattg
     8941 tcaacattgc gcaaagctca tttggacaag ggatttcagt gacccagacg caaatgattc
     9001 gtgcctttac agctattgct aatgacggtg tcatgctgga gcctaaattt attagtgcca
     9061 tttatgatcc aaatgatcaa actgctcgga aatctcaaaa agaaattgtg ggaaatcctg
     9121 tttctaaaga tgcagctagt ctaactcgga ctaacatggt tttggtaggg acggatccgg
     9181 tttatggaac catgtataac cacagcacag gcaagccaac tgtaactgtt cctgggcaaa
     9241 atgtagccct caagtctggt acggctcaga ttgctgacga gaaaaatggt ggttatctag
     9301 tcgggttaac cgactatatt ttctcggctg tatcgatgag tccggctgaa aatcctgatt
     9361 ttatcttgta tgtgacggtc caacaacctg aacattattc aggtattcag ttgggagaat
     9421 ttgccaatcc tatcttggag cgggcttcag ctatgaaaga ctctctcaat cttcaaacaa
     9481 cagctaaggc tttagagcaa gtaagtcaac aaagtcctta tcctatgcct agtgtcaagg
     9541 atatttcacc tggtgattta gcagaagaat tgcgtcgcaa tcttgtacaa cccatcgttg
     9601 tgggaacagg aacgaagatt aaaaacagtt ctgctgaaga agggaagaat cttgccccga
     9661 accagcaagt ccttatctta tctgataaag cagaggaggt tccagatatg tatggttgga
     9721 caaaggagac tgctgagacc cttgctaagt ggctcaatat agaacttgaa tttcaaggtt
     9781 cgggctctac tgtgcagaag caagatgttc gtgctaacac agctatcaag gacattaaaa
     9841 aaattacatt aactttagga gactaatatg tttatttcca tcagtgctgg aattgtgaca
     9901 tttttactaa ctttagtaga aattccggcc tttatccaat tttatagaaa ggcgcaaatt
     9961 acaggccagc agatgcatga ggatgtcaaa cagcatcagg caaaagctgg gactcctaca
    10021 atgggaggtt tggttttctt gattacttct gttttggttg ctttcttttt cgccctattt
    10081 agtagccaat tcagcaataa tgtgggaatg attttgttca tcttggtctt gtatggcttg
    10141 gtcggatttt tagatgactt tctcaaggtc tttcgtaaaa tcaatgaggg gcttaatcct
    10201 aagcaaaaat tagctcttca gcttctaggt ggagttatct tctatctttt ctatgagcgc
    10261 ggtggcgata tcctgtctgt ctttggttat ccagttcatt tgggattttt ctatattttc
    10321 ttcgctcttt tctggctagt cggtttttca aacgcagtaa acttgacaga cggtgttgac
    10381 ggtttagcta gtatttccgt tgtgattagt ttgtctgcct atggagttat tgcctatgtg
    10441 caaggtcaga tggatattct tctagtgatt cttgccatga ttggtggttt gctcggtttc
    10501 ttcatcttta accataagcc tgccaaggtc tttatgggtg atgtgggaag tttggcccta
    10561 ggtgggatgc tggcagctat ctctatggct ctccaccaag aatggactct cttgattatc
    10621 ggaattgtgt atgtttttga aacaacttct gttatgatgc aagtcagtta tttcaaactg
    10681 acaggtggta aacgtatttt ccgtatgacg cctgtacatc accattttga gcttggggga
    10741 ttgtctggta aaggaaatcc ttggagcgag tggaaggttg acttcttctt ttggggagtg
    10801 ggacttctag caagtctcct gaccctcgca attttatatt tgatgtaaga atggcaccct
    10861 gatgtttcag ggtgtttttg tgtttaaata cacaatgaaa atcaaagaac aaactagaaa
    10921 gctaacttta ggctgctcaa aatatagtag attgaaacta aaatagtaca catctacttc
    10981 taaaatattg ttagaaatcg atttgactgt cctgattgat ttgtcctgtt cttatttcat
    11041 tttactatac agttttgaga tggttgatag aactgacgaa gtcagctcaa aacacggttt
    11101 tgaggttgta gataaggaga agctgatgtg gtttgaagag gttttcgaag agtgtaaaaa
    11161 aatattggtc agttaaagtc aaaactcttg accttttctg accaatgtag tatattatga
    11221 acgtaaggta aatgaaagcc ttactagaac acttatttaa agtaaaatag aaagaggtgg
    11281 gtctatgttt catctagaaa tcttcagaag taaagatagt ctactcctgc ttgaaaaaga
    11341 aaaaccagaa atagtacgta gggtagcgat ctagctagtc taaatttttt aaaacaatgg
    11401 tcaaagatag tcaatatcag taatcataac taagtaaaca aaaagaggta aagaatatga
    11461 ataacaactt taataatttt aataacatgg atgatttatt taaccaattg atgggtggta
    11521 tgcgaggata cagttctgaa aatcgccgtt acttaattaa tggacgcgaa gtcacacctg
    11581 aggaatttgc tcactatcgt gcgactggtc aattaccagg aaatgcagaa actgatgtgc
    11641 aaatgccaca acaggcatca ggtatgaaac aagacggtgt ccttgcaaaa ctaggtcgaa
    11701 acttaacagc agaagcgcgt gagggcaagt tggatcctgt tatcggacga aacaaggaaa
    11761 ttcaagaaac atctgaaatc ctctcacgcc gcaccaagaa caatcctgtt ttggtcggag
    11821 atgcaggtgt tggtaagaca gcagttgtcg aaggtctagc gcaagccatt gtgaacggag
    11881 atgttcctgc tgctatcaag aacaaggaaa ttatttctat tgatatctca ggtcttgagg
    11941 ctggtactca ataccgtggt agctttgaag aaaatgtcca aaacttagtc aatgaagtga
    12001 aagaagcagg gaatattatc ctcttctttg atgaaattca ccaaattctt ggtgctggta
    12061 gcactggtgg agacagtggt tctaaaggac ttgcggatat tctcaagcca gctctctctc
    12121 gtggagaatt gacagtgatt ggggcaacaa ctcaagacga ataccgtaac accatcttga
    12181 agaatgctgc tcttgctcgt cgtttcaacg aagtgaaggt caatgctcct tcagcagaga
    12241 atacttttaa aattcttcaa ggcattcgtg acctctatca acaacaccac aatgtcatct
    12301 tgccagacga agtcttgaaa gcagcggtgg attattctgt tcaatacatt cctcaacgta
    12361 gcttgccaga taaggctatt gaccttgtcg atgtaacggc tgctcacttg gcggctcaac
    12421 atccagtaac agatgtgcat gctgttgaac gagaaatcga aacggaaaaa gacaagcaag
    12481 aaaaagcagt tgaagcagaa gattttgaag cagctctaaa ctataaaaca cgcattgcag
    12541 aattggaaaa gaaaatcgaa aaccacacag aagatatgaa agtgactgca agtgtcaacg
    12601 atgtggctga atccgtggaa cgaatgacag gtatcccagt atcgcaaatg ggagcttcag
    12661 atatcgaacg tttgaaagat atggctcatc gcttgcaaga caaggtgatt ggtcaagata
    12721 aggccgtaga agctgtagct cgtgctatcc gtcgtaaccg tgctggtttt gatgaaggaa
    12781 atcgcccaat cggcagcttc ctctttgtag gatctactgg ggttggtaag acggagcttg
    12841 ctaagcaatt ggcactcgat atgtttggaa cccaggatgc gattatccgt ttggatatgt
    12901 ctgaatacag tgaccgcaca gctgtttcta agctaattgg tacaacagca ggctatgtgg
    12961 gttatgatga caatagcaat accttaacag aacgtgttcg tcgcaatcca tactctatca
    13021 ttctcttgga tgaaattgaa aaggctgatc ctcaagttat tacccttctc ctccaagttc
    13081 tagatgatgg tcgtttgaca gatggtcaag gaaatacagt aaacttcaag aacactgtca
    13141 ttattgcgac ctcaaatgct ggatttggct atgaagccaa cttgacagaa gatgcggata
    13201 aaccagaatt gatggaccgt ttgaaacctt tcttccgtcc agaactcctc aaccgcttta
    13261 atgcagtcat cgagttctca cacttgacta aggaagacct ttctaagatt gtagatttga
    13321 tgttggctga agttaaccaa accttggcta agaaagacat tgacttggta gtcagtcaag
    13381 cggctaaaga ttatatcaca gaagaaggtt acgacgaagt catgggggtt cgtcctctcc
    13441 gtcgcgtggt tgaacaagaa attcgtgata aggtgacaga cttccacttg gatcatttag
    13501 atgctaaaca tctggaagca gatatggaag atggcgtttt ggttattcgt gagaaagtct
    13561 aagacagaat tttgaggata aaaaagaagg agccagctga aaaaaactgg ttccttttga
    13621 ggtacgacgg gcatgtcgta tagtagaagt gtattattct agtttcaatc tactatagta
    13681 gctcagaagt cggtacttaa acgtgctata tcaaaaccag tccttgagaa acgtggactg
    13741 gtttcgtgtt tggattatta ccttgaacga catgcgttaa aagttagttg aaccgccgta
    13801 tgccgaacgg cacgtacggt ggtgtgagaa gggctagaga ttatccccta ctcgatttta
    13861 aatcacatga cgttcaaagg catcatctga aatcccttgt tccaagatga gttttgccca
    13921 ttctttagca gagaagaggc tgtggtcctt gtagtttccg caagattcga tggttgtccc
    13981 tgggacatct tcccaagtag tagtttcagc gatttccttg agcgaatcct tgataacagc
    14041 tgcgatttta gcactggtgt gacgtcccca cataatcatg tggaagcctg tgcggcaacc
    14101 aaatggtgaa cagtcaatca tgccgtcaat gcgggtacgg atgagtttgg ctaagaggtg
    14161 ctcgatagtg tgaaggccgg cagtagggat agagtcttcg tttggttgca ccaagcgaat
    14221 atcataattg gagatgatgt ctccttttgg tcctgtttct tccccaatca agcgaacata
    14281 gggtgctttg acaatggtgt ggtcaagttc aaaactttcg acaataactt cttttgacat
    14341 ggtaaatcct ttcagttttc ttctctcatt atatcataaa ggttgttcct gagacagaga
    14401 gaaaacctct ccgaggctag agaggttgaa atctttactt acgatataag cggtcgtatt
    14461 ggtagtatgg gtcaaaggtt acgttgatac ccagtttacg aaggacattc ttgtcttcat
    14521 cagtcaagat gatggttgag tgggcttcgc ttcctttgag gttgccgagt tcttccatag
    14581 cgcgggcagc atcaggattt tctgtagctg tgatagcaag tgcaatcagg atttcatttg
    14641 aatgaaggcg tggattgcgg ctaccgagat gatcgatttt aagaccttgg attggcttaa
    14701 caacttcagg ctcgattagt tttacttctt tagcgatgtc agctgatttt ttgatggcgt
    14761 tgatcaaggc agcggctgta ggcccaaaga gttctgagtt cttaccagtg acgattttcc
    14821 catttggcaa ttcaaaggct agggctggtc caccagtttc ttctgctttt tggcgcgcaa
    14881 cgacagcaac cttacggtct gcaggtgtga taccgaggtc gttcatgagc aactcaattt
    14941 tcttgacggc agcttcgcca actttttcag ctttgaagtc aagaactgtt tgatagtaac
    15001 ggcggatgat ttcttgttta gaagcttcga cagcagactc gtcatctgta atagcgaaac
    15061 caaccatgtt gacacccata tctgtcggtg aagcgtatgg tgattttccg agaatacgtt
    15121 ccaacatgcg cttgagcact gggaagattt cgatatcacg gttgtagttg acagtggttt
    15181 ctccataggt ttgaagatgg aaggggtcaa tcatgttgac atcatcaagg tcagctgtgg
    15241 cagcttcata agccaagtta actggatgat gaaggggaag attccaaaca gggaaggttt
    15301 caaatttagc gtagccagac ttgatgccat tgatttggtc gtggtacata ttggacatac
    15361 acgttgccaa ttttccagaa ccgggtccag gagcggttac gacaatcaag ttgcgactgg
    15421 ttttgatgta gtcgtttttg cccatgcctt ctggggaaat gatgtgatcc atatccgtcg
    15481 gatatccttt gattggataa tgaagataag aatcaattcc gtttttctca agttggttgc
    15541 ggaaggcatc tgcagcgagt tggccagcgt attgtgtaat gacaacggaa ccaacaaaaa
    15601 tccctaattc attgaatttg tcaatcaaac gaagaacttc ttggtcataa gaaatgccta
    15661 agtcgccacg tgctttggaa tgttcaatgt tgctagcatt aatggcaatc acaacctcaa
    15721 cctgctcttt caattcttgc aagagcttga ttttgttgtc aggttcataa ccaggaagga
    15781 cacgagcagc gtggaaatct tctaacattt taccgccaaa ctctaagtag agcttgccgt
    15841 caaattggtt aatgcgctcc aaaatatggt cgcgttgtaa attcaaatat tgttcagaac
    15901 taaaagcttg ttttttcatt tttttacctc tggactctat tataataaaa aattggaagt
    15961 taggaaacta cggagctaaa aaagaaatta aaaagattaa gcaaacgctt gcacaaaatt
    16021 ttaaaaagtg ctatcatata ctatagatta ttaaaataat gaggtaaaca gatgcaagaa
    16081 aaatggtggc ataatgccgt agtctatcaa gtctatccaa agagttttat ggatagtaat
    16141 ggagatggag ttggtgattt gccaggtatt accagtaagt tgaactatct agctaagcta
    16201 ggaatcacag cgatttggct ttctcccgtt tatgacagcc ctatggatga taatggctac
    16261 gatattgctg attatcaagc gattgcaacg atttttggaa ccatggagga tatggatcaa
    16321 ctgattgcgg aagctaagaa gcgtgacatt cgtatcatca tggacttggt ggttaatcat
    16381 acctcagatg aacatgcttg gtttgtcgaa gcctgtgaaa atactgatag ccctgagcga
    16441 gactactata tctggcgcga tgaacccaat gacctagatt ctatctttag tgggtctgct
    16501 tgggaatacg atgaaaagtc aggtcaatac tatctccact ttttcagcaa gaaacagccg
    16561 gatctcaact gggaaaatga aaaacttcgc cagaaaattt atgagatgat gaacttctgg
    16621 attgataaag gtattggtgg tttccgtatg gatgttattg acatgattgg caaaattcct
    16681 gacgagaagg tagtcaataa tggtcctatg ctccatccct atctcaagga aatgaatcag
    16741 gcgacctttg gagataagga tctcttgaca gtaggggaga cttggggagc aacgccagag
    16801 attgccaagc tctactctga tccaaagggg caagaattgt ctatggtctt ccagtttgaa
    16861 catatcggtc ttcagtatca ggaaggtcag cctaaatggc actatcaaaa agaactgaat
    16921 atcgctaagt taaaagaaat cttcaacaaa tggcagacag agttaggagt tgaggacggc
    16981 tggaattccc tcttctggaa caaccatgac ctccctcgta ttgtctcaat ctggggaaat
    17041 gaccaagaat accgcgaaaa atctgccaaa gcctttgcaa tcttacttca tctcatgaga
    17101 ggaactcctt atatctacca aggtgaggag attgggatga ccaactatcc gtttgaaaca
    17161 ctagatcaag tagaagatat tgaatctctc aactatgcgc gtgaggctct tgaaaaaggt
    17221 gttccgatgc aagaaatcat ggacagtatc cgtgttattg gacgtgacaa tgcccgtacc
    17281 cctatgcaat gggacgagag caaaaacgct ggtttctcaa caggtcaacc ttggttggca
    17341 gttaatccaa attacgagat gatcaacgtc caagaagcgc tggcaaatcc agattctatt
    17401 ttctatacct atcagaaact ggtccaaatt cgcaaggaga atagctggct aattcgagct
    17461 gactttgaat tgcttgatac ggctgataag gtctttgctt atatacgtaa ggatggtgac
    17521 cgtcgcttcc tagttgtggc taacttgtcc aatgaagagc aagacttgac agtagaagga
    17581 aaagtcaaat ctgtcttgat tgaaaacact gcggctaaag aagtacttga aaaacaggtc
    17641 ttggctccat gggatgcttt ctgtgtggaa atgactgact agaatgagca aacctcaagt
    17701 ttttgaagct tgaggctttt tactatagtg gattgaaact agaatagtgc acctctgctt
    17761 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttgtcctat tcttatttca
    17821 ttttgctata cttgtagttg aggagaatta agctcctcac tagtaaactc ttcataatcc
    17881 tttttatttt tatgaagata ttgtttgaaa gatatgagtt tccacggatg ggtttgtgga
    17941 gggatatact tgcgtctttc tttttttgtt ctggttcttg ttcaaagttt ttcgaataga
    18001 gttcatgatt tagtagctcc tttgtgtgat agattttgtc agcgatattg aggtagatgt
    18061 ctccgtcaaa tgcttttata actaatgctt tcgtctttct gatgaaatag acttcttttc
    18121 cttgttcggt agggatatag taacgatttt ggaatcggat atggtgtcca ctatcgacga
    18181 ctctctccgc cagtctagcc agaatgagat tcctttcaga ggggttagga acctcctcga
    18241 agacagagag ttttgtcttg tttccaaact gttcattaaa ggtttgaatg taggaaagca
    18301 ggaaggtatt ggcttcttcc aaggtatgaa tattgttttg ttccagttcg ataggcaggc
    18361 gagattgtag tgtctgattg agtctttcga ctctcccttt agcttgaggg atagaggttg
    18421 tctcaaggag aatccctagt tggtgacagg cgtatccaaa ctgtgtatgg gtatcgtcct
    18481 ccattttctt agagttggag gcttgatagg taaagaccgt tctcttatct gttttaattt
    18541 gaaggggaat gccgtgattg gctaagattt gttcgaggac atgatagtaa gcattcaagt
    18601 tctcttgttt atcaaaataa gcgcctagga tattgccaga agcatcatca atggttaagt
    18661 gtaagttaga tgtttgggct ccaaactagg catgagggct ggcatccatt tgaatgagtt
    18721 caccagcaaa tttctttctg ggtctactag gatgtacttt tttagggtct tcaaggaagt
    18781 tttcagccgt cggtaagatt ggattgtcta gggggtgatt caggttcagt ttagcttgtt
    18841 ttcttactct cttctttgtc tttctatggg acttaggcga caggatattt ttcttataga
    18901 gtatttttct aacagttgta tcagagagct gaattccttc ttcttcagct agcaattcac
    18961 agaaatgaag gacatttggt ttatatgttt cataggagag gtattttttt aggagacgtt
    19021 ctttgatttc atcagggatt gcatgttttg gttttcgatt tctgtttccg tgtctgaagg
    19081 cttcttttcc tttcagttga taggctagta gcagacgatt gatttgtctt tcagaaagat
    19141 tgagctcgac acaggctcgt ttctttgttt tctttccttg ggctatagct tttatcacaa
    19201 gatatttttt cgtttcattc atattcagtt ggatcctttt catatgacta ttctaccaaa
    19261 tgggacattt tcacgttcga tttactaaag acattatcac attcgaatta cacaagatgc
    19321 agatagtgaa aaaaaggtgt agacattacc gtaaaaaagt gatataatcg tatgatgttc
    19381 aatgtatagg tgttaatcat gagtagacgt tttaaaaaat caggttcaca gaaagtgaag
    19441 cgaagtgtta atatagtttt gttgactatt tatttattgt tagtttgttt tttattgttc
    19501 ttaatcttta agtacaatat ccttgctttt agatatctta atctagtggt aactgcgtta
    19561 gtcctactag ttgccttggt agggctactc ttgattatct ataaaaaagc tgaaaaattt
    19621 actatttttc tgttggtgtt ctctatcctt gtcagctcag tgtcgctctt tgcagtacag
    19681 cagtttgttg gactgaccaa tcgtttaaat gcgacttcta attactcaga atattcgctc
    19741 agtgtcgctg ttttagcaga tagtgagatc gaaaatgtta cgcaactgac gagtgtgaca
    19801 gcaccgactg ggactgataa tgaaaatatt caaaaactac tagctgatat caagtcaagt
    19861 cagaatactg atttgacggt cgaccagagt tcgtcttact tggctgctta caagagtttg
    19921 attgcagggg agactaaggc cattgtccta aatagtgtct ttgaaaatat catcgagtca
    19981 gagtatccag actacgcatc gaagataaaa aagatttata ccaagggatt cattaaaaaa
    20041 gtagaagctc ctaagacgtc taagaatcag tctttcaata tctatgttag tggaattgac
    20101 acctatggtc ctattagttc ggtgtcgcga tcagatgtca atatcctgat gactgtcaat
    20161 cgagatacca agagaatcct tcttacaaca actcctcgag attcatatgt tcctattgct
    20221 gatggtggaa ataatcaaaa ggataaattg actcatgctg gtatatatgg ggttgattca
    20281 tccattcata ccctagagaa cctttatggt gtagatatta attattatgt tcgtttgaat
    20341 tttacctcat ttttgaaatt gattgactta ttgggagggg tagatgttca taatgatcaa
    20401 gagttttcag ctctacatgg gaagttccat ttcccagtag ggaatgtcca tctagactct
    20461 gagcaagctc taggttttgt acgtgaacgc tactcactag ccgatggaga ccgtgaccgt
    20521 ggtcgcaacc aacaaaaggt gattgtggct atccttcaaa aattaacgtc aaccgaagcg
    20581 ctgaaaaatt atagtacgat cattgatagc ttgcaagatt ctatccaaac aaatatgcca
    20641 cttgagacta tgataaattt ggtcaatgct cagttagaaa gtggagggaa ttataaagta
    20701 aattctcaag atttaaaagg tacaggtcgg acggatcttc cttcttatgc aatgccagac
    20761 agtaacctct atgtgatgga aatagatgat agtagtttag ctgtagttaa agcagctata
    20821 caggatgtga tggagggtag atgaaatgat agacatccat tcgcatatcg tttttgatgt
    20881 agatgacggt cccaagtcaa gagaggaaag caaggctctc ttgacagaat cctacaggca
    20941 gggggtgcga accattgtct ctacctctca ccgtcgcaag ggcatgtttg aaactccgga
    21001 agagaagata gcagaaaact ttcttcaggt tcgggaaatt gcaaaagaag tagcagatga
    21061 tttagtcatt gcttatggcg cagagatata ctatactctg gatgctctag aaaagctaga
    21121 aaaaaaagaa attcctaccc tcaatgatag tcgttatgcc ttgatagagt ttagtatgaa
    21181 cactccttat cgcgatattc atagcgcctt gagcaagatc ttgatgttgg gaattactcc
    21241 agtcattgcc cacattgagc gctatgatgc tcttgaaaat aacgaaaaac gtgttcgtga
    21301 actgattgat atgggctgtt acacgcaagt aaatagttca catgtcctca aacccaaact
    21361 ttttggcgaa cgttataaat tcatgaaaaa aagagctcag tattttttgg aacgtgattt
    21421 agttcatgta gttgcaagtg acatgcacaa tttagacagt agacctccat atatgcaaca
    21481 ggcatatgat atcattgcta agaaatatgg agcgaaaaaa gcgaaagaat tttttgtaga
    21541 taatcccaga aaaattataa tggatcaatt aatttaggag aaaatatgaa ggaacacaac
    21601 actttggaaa tcgatatatt gcaactattc agagctttat ggaaaagaaa gttggtcatt
    21661 ttattagtgg caattataac ttcttcagtt gcttttgcct acagtacttt tgttatcaaa
    21721 cctgagttta ctagtacgac tcggatttat gtagttaacc gtaatcagga agagaagtct
    21781 ggtttaacca atcaagactt gcaggcagga acttatctgg taaaagacta ccgtgagatt
    21841 atcctttcgc aggatgtttt ggaggaagtt atttctgatt tgaaactaga tttgacgcca
    21901 aaaggtttgg ctaataaaat taaagtaaca gtaccagttg atacccgtat tgtctctgtt
    21961 tcagttaatg atcgagttcc tgaagaggca agccgtatcg ctaactcttt gagagaagta
    22021 gctgctcaaa aaattatcag tattactcgt gtttctgatg tgacaacact ggaggaggca
    22081 agaccggcga tatcaccgtc ttcgccaaat attaaacgca atatactaat tggttttttg
    22141 gcaggggggg ttggaactgg tgttatagtt cttcttcttg aacttttgga cactcatgtg
    22201 aaacgtccgg aagatatcga agatacactg cagatgacac ttttgggagt tgtaccaaac
    22261 ttgagtaagt tgaaatagga gagaggaatg ccgacattag aaatagcaca aaaaaaactg
    22321 gagttcatta agaaggcaga agaatattac aatgccttgt gtacaaatat acagttgagc
    22381 ggagataaac taaaagtaat ttccgttact tctgttaacc ctggggaagg aaaaacaact
    22441 acttccgtaa atatagcaag gtcgtttgcg cgtgcaggct ataaaactct tttgatcgat
    22501 ggcgatactc gaaattcagt tatgtcagga ttttttaaat ctcgtgaaaa aattacaggg
    22561 ctaacagaat ttttatctgg gacagctgat ttatctcacg gtttatgtga tacaaatatt
    22621 gaaaatttat ttgtagttca atcggggtct gtatcaccaa accctacagc cttgttacaa
    22681 agtaaaaatt ttaatgatat gattgaaaca ttgcgtaaat attttgatta tatcattgtt
    22741 gatacagcac ctattggaat tgttattgat gcggcaatta tcactcaaaa gtgtgatgcg
    22801 tccatcttgg taacagcaac aggtgaggtg aataaacgtg atgtccaaaa agcgaaacaa
    22861 caattagaac aaacagggaa actgttttta ggtgtcattc tcaataaatt tgatgttcaa
    22921 cataaaaaat atggttctta cggtgactat ggtaattatg gtaaaaaata acttaggaaa
    22981 gattttatgg atgaaaaagg attgaaaatt tttctggcag tattacagag tattattgtc
    23041 attttattgg tttattttct tagctttgtt agagagacag aacttgaacg ttcttcgatg
    23101 gttatactat accttctcca cttttttgta ttctatttta gttcctatgg taataatttt
    23161 tttaaaagag ggcacttagt tgagtttaat agtactataa gatatatttt tttctttgca
    23221 atagctataa gtgtattaaa cttttttata gcggaacggt ttagtatctc tagaagagga
    23281 atggtatact tcttaacttt agaaggaata tccttatact tgttaaattt cttagtaaag
    23341 aaatattgga agcatgtgtt ttttaatcta aaaaatagca agaaaatttt actgttaaca
    23401 gtaacgaaaa atatggaaaa agttcttgat aaattgctag aatctgatga actttcatgg
    23461 aaattggtag cagtaagtgt tttggataaa tctgattttc aacatgataa aatacctgta
    23521 attgaaaagg aaaaaattat tgaatttgca acgcatgaag ttgtggatga ggtgtttgtc
    23581 aatcttccag gagagagcta cgatattgga gaaattatct ctaggtttga gacaatgggg
    23641 atagatgtaa ctgtaaatct taaagcattt gataagaatt tgggtcgcaa taaacaaatt
    23701 catgagatgg taggattgaa tgtagtcact ttctctacaa atttttataa aactagtcat
    23761 gtgatttcaa agagaattct cgatatttgt ggtgccacta ttggccttgt tctttttgct
    23821 atagctagtc tagttttagt tccattgatt cgtaaagatg gcggaccagc tatttttgct
    23881 caaactcgta tagggaaaaa tggtcgacat tttacctttt ataaattccg ttcgatgcgg
    23941 atcgatgctg aagctatcaa agaacaattg atggatcaaa atacgatgca aggtggtatg
    24001 tttaagatgg acaatgatcc tcgtgttaca aaaattggtc gctttattcg taaaaccagt
    24061 ttggatgaat tgccgcagtt ttggaatgtc tttataggag atatgagttt ggtgggaaca
    24121 cgtccaccta cagtagacga gtatgatcag tatactccag aacagaaacg tcgactcagc
    24181 tttaaacctg gtattacagg tttatggcag gttagcggcc gtagtaaaat aaccgatttt
    24241 gacgatgttg taaaattaga tgtggcttat attgataatt ggacaatctg gaaagatatt
    24301 gaaattttgc ttaaaactgt taaagttgta tttataagag atggagcgaa gtaaggaatg
    24361 aaagtatgtc tagttggatc tagtggaggc catttaactc atttgtattt attaaaacct
    24421 ttctggaatg ataaagaaag attttgggtt acttttgata aggcggacgc tcggagtgta
    24481 ctctctgagg aagttgtata tccctgttat tatccaacca atcgtaatat aaaaaattta
    24541 ataaaaaata cttttctcgc ctataaaatt ttaaaaaaag agagaccaga tttgattatt
    24601 tcttctggtg ccgctatcgc tgttcctttc ttttatattg ggaagttatt tggatcaaag
    24661 acagtgtata tagaagtgtt tgatagaatt gatgcttcaa cactgacagg aaaacttgtt
    24721 tatccagtaa cggataggtt tattgtacaa tgggaagaaa tgaaaaaagt atacccaaaa
    24781 gcaattaacc taggagggat attctaatga tttttgtgac tgtaggtaca cacgaacaac
    24841 aatttgatcg attgattaaa gaagttgatt atctaaaaaa agaaaatctt attcaagatg
    24901 aagtatttat tcaaatagga tattccagtt atattccgaa atattgtgag tgggaaaaga
    24961 taatttctta tgaaaaaatg aatcaattga ttaaggaatc agatattatc attactcatg
    25021 gtggaccagc gacgtttatg ggggttattg ctaaaggaaa agttccgata gttgttccga
    25081 ggcaaaaaaa atttggagag catgtgaatg accatcagct tcaattcgta aaactgacga
    25141 aagaaatata caattttata gtcatagatg a
//
LOCUS       DAVLHB010000029        24944 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLHB010000029 DAVLHB010000000
VERSION     DAVLHB010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24944
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.029"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            152..277
                     /gene="comC"
                     /locus_tag="VXE36_001309"
     CDS             152..277
                     /gene="comC"
                     /locus_tag="VXE36_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0779612.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            298..1623
                     /locus_tag="VXE36_001310"
     CDS             298..1623
                     /locus_tag="VXE36_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0779613.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            1620..2372
                     /locus_tag="VXE36_001311"
     CDS             1620..2372
                     /locus_tag="VXE36_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0779614.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            2424..2495
                     /locus_tag="VXE36_001312"
     tRNA            2424..2495
                     /locus_tag="VXE36_001312"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2457..2459,aa:Glu,seq:ttc)
     gene            2501..2574
                     /locus_tag="VXE36_001313"
     tRNA            2501..2574
                     /locus_tag="VXE36_001313"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2535..2537,aa:Asn,seq:gtt)
     gene            complement(2614..3156)
                     /locus_tag="VXE36_001314"
     CDS             complement(2614..3156)
                     /locus_tag="VXE36_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0779615.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDKN"
     gene            3314..4081
                     /locus_tag="VXE36_001315"
     CDS             3314..4081
                     /locus_tag="VXE36_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEV0779616.1"
                     /translation="MIGISLIPDLYNIIFLSLMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            4166..4441
                     /locus_tag="VXE36_001316"
     CDS             4166..4441
                     /locus_tag="VXE36_001316"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779617.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFLQQYQQI"
     gene            4531..4845
                     /locus_tag="VXE36_001317"
     CDS             4531..4845
                     /locus_tag="VXE36_001317"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0779618.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(4946..7498)
                     /locus_tag="VXE36_001318"
     CDS             complement(4946..7498)
                     /locus_tag="VXE36_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0779619.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSNLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQILKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(7560..9182)
                     /locus_tag="VXE36_001319"
     CDS             complement(7560..9182)
                     /locus_tag="VXE36_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0779620.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            9388..10413
                     /gene="trpS"
                     /locus_tag="VXE36_001320"
     CDS             9388..10413
                     /gene="trpS"
                     /locus_tag="VXE36_001320"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0779621.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            10565..12043
                     /gene="guaB"
                     /locus_tag="VXE36_001321"
     CDS             10565..12043
                     /gene="guaB"
                     /locus_tag="VXE36_001321"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0779622.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(12094..13191)
                     /gene="recF"
                     /locus_tag="VXE36_001322"
     CDS             complement(12094..13191)
                     /gene="recF"
                     /locus_tag="VXE36_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0779623.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(13194..13562)
                     /gene="yaaA"
                     /locus_tag="VXE36_001323"
     CDS             complement(13194..13562)
                     /gene="yaaA"
                     /locus_tag="VXE36_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0779624.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQASRFPGR"
     gene            13721..14971
                     /locus_tag="VXE36_001324"
     CDS             13721..14971
                     /locus_tag="VXE36_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0779625.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLATDMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYPSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            14968..16251
                     /locus_tag="VXE36_001325"
     CDS             14968..16251
                     /locus_tag="VXE36_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0779626.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            16293..17114
                     /locus_tag="VXE36_001326"
     CDS             16293..17114
                     /locus_tag="VXE36_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0779627.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            17125..17670
                     /gene="pgsA"
                     /locus_tag="VXE36_001327"
     CDS             17125..17670
                     /gene="pgsA"
                     /locus_tag="VXE36_001327"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0779628.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIVLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            17667..18494
                     /locus_tag="VXE36_001328"
     CDS             17667..18494
                     /locus_tag="VXE36_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0779629.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRKIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            18479..19318
                     /locus_tag="VXE36_001329"
     CDS             18479..19318
                     /locus_tag="VXE36_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0779630.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            19311..20105
                     /locus_tag="VXE36_001330"
     CDS             19311..20105
                     /locus_tag="VXE36_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0779631.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            20164..20982
                     /gene="mreC"
                     /locus_tag="VXE36_001331"
     CDS             20164..20982
                     /gene="mreC"
                     /locus_tag="VXE36_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0779632.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            20982..21476
                     /gene="mreD"
                     /locus_tag="VXE36_001332"
     CDS             20982..21476
                     /gene="mreD"
                     /locus_tag="VXE36_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0779633.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            21570..22748
                     /locus_tag="VXE36_001333"
     CDS             21570..22748
                     /locus_tag="VXE36_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0779634.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            22972..23751
                     /gene="rpsB"
                     /locus_tag="VXE36_001334"
     CDS             22972..23751
                     /gene="rpsB"
                     /locus_tag="VXE36_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0779635.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            23830..24870
                     /locus_tag="VXE36_001335"
     CDS             23830..24870
                     /locus_tag="VXE36_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0779636.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT         8015 a         3908 c         5066 g         7955 t
ORIGIN      
        1 gctgggaatt ttcccggctt ttttcttaaa aaagtacact ttgggagaaa aaaatgacag
       61 ttgagagaat tttatctaaa acgaaattcc attttgtata atggtttttg taagttagct
      121 tacaagaaaa aacattttag gagattttat tatgaaaaac acagttaaat tggaacagtt
      181 tgtagctttg aaggaaaaag acttacaaaa gattaaaggt ggggagatga ggttgtcaaa
      241 attcttccgt gattttattt tacaaagaaa aaagtaatga aataagggga aagagtaatg
      301 gatttatttg gatttgggac ggttattgtt cattttttaa ttattagtca cagttaccat
      361 tttatttgta aaggtcaaat aaatagaaaa gaattattcg tttttggtgc ttatacatta
      421 ctaacagaaa tagtatttga ttttccctta tatattctat atttagatgg gttagggatt
      481 gaaagatttt tatttccttt gggattatat tcctattttc gatggatgaa acagtatgag
      541 agggatagag gactattcct aagtttacta ctatctcttt tatatgagag cactcataac
      601 tttctgtccg taactttctc ctctataaca ggagataatt ttgttttaca atatcatttc
      661 ccattctttt tcgttgtgac ggtgttaacc tattttgtta cattaaaaat catttactat
      721 ttccatttgg aactagccta ttttgacgag gactaccttt atcctttctt gaaaaaagta
      781 ttttttgctt tactattgct acatattgta tctttcgttt cagatatggt aagtacgatt
      841 aaacatttga atagttttgg aagtattttg tcatctattg tctttatctc tctccttttg
      901 accttctttg caatgaattc tcataaagtt caaatggaga aagagattgc tttgaagcag
      961 aagaaatttg aacagaaaca tttacagaat tacacagatg aaattgttgg tctgtataat
     1021 gaaatccgtg gttttcgaca tgattatgct ggaatgcttg tcagcatgca gatggcaatt
     1081 gacagtggta atttacagga aattgacaga atttacaatg aagttttagt caaagcaaat
     1141 cataaattgc gttcagataa gtacacttac tttgatttga acaacataga agactcagct
     1201 ttacgaagtt tggttgctca gtcaattgtc tatgctcgaa ataatggtgt agagtttaca
     1261 ctggaagtaa aagatacgat taccaagctt ccaattgaac tattggattt ggttcgtatc
     1321 atgagcgttt tattgaataa tgctgtcgaa ggatcggctg atagctataa aaagcagatg
     1381 gaagtagcag ttattaagat ggaaactgaa acagttattg tgattcagaa ttcatgtaaa
     1441 atgacgatga ctccttcagg agatctattt gccttaggat tctccactaa gggaagaaat
     1501 cgcggagtcg gattaaataa tgtgaaagaa ctactagata agtacaacaa tattatttta
     1561 gaaacagaga tggaaggcag tacatttaga caaatcatta gatttaagag ggaatttgaa
     1621 tgaaagtttt aattttagaa gatgttattg aacatcaagt gagactagag agaatattgg
     1681 atgaaatttc gaaagaatcg aatattccaa tatcatacaa gacaacggga aaagtccgtg
     1741 aatttgaaga atacattgaa aatgatgaag taaatcagct ttatttccta gatatcgata
     1801 ttcatggaat tgagaaaaag ggatttgaag tggctcagct cattcgtcat tacaatcctt
     1861 acgctattat cgtctttatc actagtcgat cagagtttgc gactctaacc tataaatatc
     1921 aggtatcagc cctagatttt gttgataagg atatcaatga tgagatgttt aagaagagaa
     1981 ttgagcaaaa tatcttctac acgaagagta tgttacttga aaatgaagat gttgtagatt
     2041 atttcgacta caattacaag ggaaatgatt taaaaattcc ttaccatgat attttgtata
     2101 ttgaaacaac aggggtatct cataaattgc gcattattgg taagaatttt gcaaaagagt
     2161 tttatggtac catgacagat attcaggaaa aggacaaaca tactcagcga ttttattctc
     2221 ctcacaagtc atttttggta aatataggca atatcagaga aattgatcga aaaaacttag
     2281 aaattgtttt ctatgaagac catcgttgtc ctatttcaag attaaaaatt agaaaattaa
     2341 aagatatttt agagaaaaaa tctcaaaagt gattgacaat tagcaagaaa ttgatataat
     2401 ggttatatct gctacagata gaaggtccgt tggtcaaggg gttaagacac cgccttttca
     2461 cggcggtaac acgggttcga atcccgtacg gactatttta tccgccatag ctcagttggt
     2521 agtagcgcat gactgttaat catgatgtcg taggttcgag tcctactggc ggagtataga
     2581 taaaagggaa cacagctgtg ttcccttttt gtatcaattt ttatcaccaa gcattttcat
     2641 aaggaagtct gttatttctt gagaactttc tttttttcca tgtgcaatcc aagtttggca
     2701 gacaccaaaa agtgcatgag ttagatagat gctactatat tctaattcgg tggtatttag
     2761 attcagttgc ataaatcgct tttgtaaatc tgtactaagc atgatatgaa gtttatttcg
     2821 taagaaattt tggatttctt tagtcccatt ttcagaaaga agggcagcca gaagtggttc
     2881 tgactctaga tattcaaaaa cttctaaaat agcgtctctt ttgtgatgag catgtttttg
     2941 aaaaatatat tcaaatgtat ggaatagctt gctttgatag tgctcaatca tatcatactt
     3001 atccttatag tgagtataga agctggaacg actaattccg gctttttcta ctaatttgac
     3061 agtagaaatt ttatcaaatg gctgttccat cagtaattgt accatagcat tttcaatagt
     3121 tcgctttgtt tttaagcgtt tgttactttc ttgcatattt cctccttgta aacaaattag
     3181 actatatgtc taaaaataga ttttttaatg tataatctat tatatcaaaa ttttagacaa
     3241 tatgtttaaa aaaggagaaa ctaagtttaa agaatggaaa gcaatttaaa aaaaaccaac
     3301 ctttattatt gtcatgatcg ggatttctct tattccagat ctgtacaata tcatattttt
     3361 gtcattaatg tgggatccat atgggcaatt gtctgactta cctgtggcag ttgtaaataa
     3421 tgataaagag gcttcctata atggtaatac tatggcaata ggaaaagaca tggtgtccaa
     3481 tttaaaagaa aataaaacct tggattttca ttttgtagat gaagaggaag gaaagaaggg
     3541 attggaagat ggcgattact atatggtagt gactttacca agtgatttat ctgaaaaaac
     3601 aactacatta tccaatattc aatcgacagc agcttatcaa tcattgacaa gtgagcaaca
     3661 aactgagata agtgattctg tatctcaaaa ttcaactgat agtattcaat cggctcagtc
     3721 aattgtagct ttagtacaag atttacaggg aagtttagaa aacttacaaa atcaatcttc
     3781 taatctttcg actttaaaaa atcaatctaa tcaagtatca cctattactt ctacttcttt
     3841 gataggattg tcaagtggat taacagagat acaaggagat gttactagca aattagttcc
     3901 tgccagtcag tcgattgcat caggtgtaaa cgcatatact acaggtgttg ataaagtttc
     3961 tcagggcgca agtcaactaa gtgaaaaaaa tgccaccttg acaggtagtt tggataaact
     4021 agtttcaggc tcaaacacct tgacacaaaa atcttctaga ttgacagcag gagttggtta
     4081 attacaatca ggatctgggc aattagcaga caaatccagt cagttacttt caggtgcttc
     4141 tccattagag aatagagcta ataaattggc agatggatct gggaaactag cagaaggtgg
     4201 aacaaagtta acttctggat tggaagattt acagacagga cttgcttctt taggacaagg
     4261 actaggtaat gctagtgatc aactcaaatc agtatcaaca gaatctaaaa atgcagagat
     4321 tttgtcaaat ccactcaatc tttcaaaaac agacaatgat caagttcctg taaatggaat
     4381 cgcaatagct ccttatatga tatcagttgc tctttttttg cagcaatatc aacaaatatg
     4441 atatttgcga aattgccttc aggacgtcat ccagagagcc gttgggcttg gttgaaatct
     4501 tgagctgaaa taaatggtat tatagctgtt ttggcaggaa ttttggtata tggaggagtt
     4561 cagcttattg gtttaactgc taatcatgag atgagaatat ttattctcat catcctaaca
     4621 agtttagtat tcatgtctat ggtgaccact ttagcaacgt ggaatagccg tataggagct
     4681 tttttctcac ttattttgct tttactacag ttagcatcaa gtgcaggtac ttatccactt
     4741 gctttgacaa atgatttctt tagatctatt aatccctggt taccaatgag ctattcagtt
     4801 tcgggattac gacaaacaat ctctatcaac aagtcatttt cctagctgtc atactagttc
     4861 tatttactag tttaggtatg ctagcctatc aacataagaa aatggaagaa gattaaaaaa
     4921 atcgaccgat taactggtcg attttttatg ccttagatga ctttcgtctg tgattataga
     4981 ttccaaatag taagagagaa gtaaaggaac agattgctcc agtaataaaa ccattgggaa
     5041 tgaaggaaag tgtaatagtt cctttcccct tgggaatgtc aactttcata aatccagttt
     5101 gagcttgttt aatttctatt ttcttaccat cttggtaggc agaccaacct ttgtcataag
     5161 gaatggtgaa gaaaatagat gtatcttgtt ggacatcata tgtagcaaaa accttgtttt
     5221 tagaagttga tactgtgaca ggttgttctt taattttttg aattgcctcg gtgaaagttt
     5281 tggtatctaa acgatagaag gtaggagatt caaatgatac ttgtgaattt ccagggaaac
     5341 taacattgat attgaaagtt tttttctctt tagtatatcc tagattaaag aaggagaaga
     5401 cattatcagt tgtaaaagtc tttttttcac catttacaag gatgtcaacc ttcttttgtt
     5461 tatcgttaga aaagtgaagg tttatgaaag agagataaac ttggctgttt tctggaactt
     5521 caatttgata ctggattgct gcatcttcat ttgaagaact tgtgacacta atcaaatcat
     5581 tagtattttc tattttttct gttttttcat aaggtattgg agaaaaataa tcaaaattga
     5641 cgttagcaag ttgatttaaa aatgaggcct gattatccaa ggtatgttca ttgaacttga
     5701 catcattgta aacagattga ctcgcaactg caatcggaag agagtattga ttttcatata
     5761 gggtaagatt atctttttga tagatatctt taaagccata cttatcaata ggactgtctg
     5821 agatattgta ctggatacca aataaactat cagccaaaat actattattt gcatatcgga
     5881 gattgagatt agtcccagag gatttaaaac caagtttatc taaagtagag cttgatgaac
     5941 gatttcgaac agatgaaaat tgagagattc cattgtagtt gaatttcata ctgtcatttc
     6001 ctgtctgagt ttgtagtttt tcagtacgag taaattgatt tccaatatat gttgagaaag
     6061 attccatagc tgggatatct cgactataag cacttcgaga agcaaatccc cattccttag
     6121 caattccgtc catttgagat gaagcattta aactcatttc aaccagtata aataaagaga
     6181 ttagaatggc aaatagattc acagatataa actttttgat aactgcaagg agtaaaagag
     6241 aatagacaac caaaaattca agagtaagca gaatattcaa atctgttaaa aaagaataat
     6301 gcgattttag atagatggta gctaaaaatc ctgctactac aagaaaaagc gaaactaaaa
     6361 aattccagac tttaagttct ttcagacgct ttaagacttc tgctgctgtg taaattaaca
     6421 aggtagagaa aatccaagca tagcgatgta aaaacatgtt tggagtatgc atgccttgcc
     6481 aaaataagtc aagagcttct atgtaaaagc ttgcaattag aaatgcaaag aatattacat
     6541 atatgagttt cacgtgaaac ttaatagatt tcagcgtaaa aaataaaatg gtcaaaataa
     6601 agggaaatag tccaacaaaa atcattggga tggccccata ctttgttgtg tcaaaggaac
     6661 caatgaattg cttagcaaag agatcaagat accagctact ttcagtttga aactttgtaa
     6721 cttcagtcaa tttttcccca tgtgtctgta aatcaaatag agtgggaaga gtcataatca
     6781 aactagccat accagctaaa aaggagataa ctatgaaatc aagaacagat gattttcgag
     6841 tcttaaagtc ccacgaaatt tgacagagat accagaaaat aagaaacaat actgtcatat
     6901 atccaaaata ataattttga ataaataaga ttgacagact tgtaaagtac aataggagtt
     6961 tcttttcagt tatcagtaga tgtaaaccag ttataattaa aggaatcaag ataaaaacat
     7021 ctagccaggt ttttatctct aattgactga cagtgaaact catcagagca taggaagtag
     7081 ataaggctag ttttaaaatc tgagggatag attgaaacaa tttattcaaa ctaaaaaagg
     7141 ttgacagacc aatcaatcca aattttaaga gagttgtcag atagatagca tctggcatat
     7201 tcgttagatc aaaaaagtaa accagaggcg cgagaaaact acccaagtaa taactagata
     7261 gggcatagaa gtttagccct agaccacttg taaaggtgta aaacagatta ctatttccat
     7321 gtaggatatt tcgtaaggct acatcaaaaa taacgtattg atgaaagcca tctcctaata
     7381 gaggagagtt gtcgctattc cagtagatac cttgagatag atatactcca gacataatca
     7441 ctacaggaat gatgaaagaa ataaaatagg ttcgatatgt ttttaaaaat gatttcatgt
     7501 tacctcgtag aatgatagaa aactcagttg gttaacccaa ctgagttttg aagttttatt
     7561 tagtctttcc aaagttcttt aacttttgct tgtacttctg cattttctag gaattcatcg
     7621 taggtttcat cgatacggtc aatgacgcca tttttagata agacaatgat atggttagcc
     7681 aaagtttgaa taaattcgtg gtcatggctg gcaaagatga ttgattcttt aaagtttttc
     7741 aatccatcat tcaagcttga gatagattcc aagtccaagt gatttgttgg atcatcaagt
     7801 acaaggacat ttgattttaa gagcatgagt tttgaaagca tgacacgaac tttttctccc
     7861 cctgacaaga catttacagg tttgttaact tcatctccag agaagagcat acggccgagg
     7921 aagccacgta ggaaagtatt gtcatcttct tctttacttg cgaattgacg caaccagtca
     7981 agaattgatt ctcctcctgc aaaatcagct gagttatctt ttggtaggta agattgacta
     8041 gttgtaactc cccacttgac agttccttca tagtcaatat ctcccatgat tgcacgaatt
     8101 aatgcagtcg tttgaatatc attttgtcca ataagtgctg tcttatcatc tggacgcaag
     8161 atgaaactaa tattatccaa gatagtttca ccatcaatct ttacagttaa attttctact
     8221 gtcaagagat cattaccaat ctcacgttcc gctttaaagt tgataaatgg atatttacga
     8281 ctagatggca caatctcttc tagctcaatc ttatcaagca ttttcttacg tgatgttgcc
     8341 tgccttgact tagaagcatt ggcagagaaa cgagcaacaa attcttgcaa ttgtttaatt
     8401 ttttcttctg ctttagcatt acggtctgct agcaatttag cagcaagctc agaagattcc
     8461 ttccagaagt cgtagtttcc gacatagagt ttgatttttc caaagtcaag gtcggccatg
     8521 tgagtacaaa ctttgtttaa gaagtgacgg tcgtgggata ctacgataac tgtgttatca
     8581 aagtcaatca agaagtcttc taaccaagta atcgattgga tatccaaacc gttagtaggc
     8641 tcgtccaaga gaagaacatc tggtttacca aaaagtgctt tggcgaggag aacctttact
     8701 ttttcaccgt tggccaattc gctcatgttt tggtagtgta attcttctgg aatgtttagg
     8761 ttttgaagta gttgagaggc ttcactctct gcttcccaac ctccaagttc ggcaaactct
     8821 ccttcgagtt cggcagcacg aaccccgtcc tcgtctgaga aatcttcctt catgtagata
     8881 gcatctttct ctttcatgat gctataaagt ttttcatttc ccatgataac gacatcaatg
     8941 gcacgttcat cttcgtagtc aaagtgattt tgacgaagaa cagagagacg ttcatctgga
     9001 ccaagagaga tgtgaccagt agtaggttcg atatctccag ctaaaatttt taaaaaggtt
     9061 gattttccgg caccattagc accgattaat ccgtaagtat ttccttctgt aaatttgata
     9121 ttgacatcat caaaaagttt gcgatcacta aaacgtagtg aaacatcaga tactgtaagc
     9181 aatgtttttc tcctatatgt gtaatatatt tattctacta gaaaatacag aaatattcaa
     9241 atttttattt gtcaattttg tgtaaattat atttacagta tcctttacac aaatctgtaa
     9301 aaagcaaggc tgatttattt tgataaatta cggttatttc attaaaaaaa tgctataatt
     9361 gaaaggacta tatcgaagga gaacaaaatg actaaaccca ttattttaac aggagaccgt
     9421 ccaacaggaa aattgcatat tggacattat gttggaagtc tcaaaaatcg agtattatta
     9481 caggaagagg ataagtatga tatgtttgtg ttcttggctg accaacaagc cttgacagat
     9541 catgccaaag atcctcaaac cattgtagag tctatcggaa atgtggcttt ggattatctt
     9601 gcagttggat tggatccaaa taagtcaact atttttattc aaagccagat tccagagttg
     9661 gctgagttgt ctatgtatta tatgaatcta gtttcgttag cacgtttgga gcgaaatcca
     9721 acagtcaaga cagagatttc tcagaaagga tttggagaaa gcattccgac aggattcttg
     9781 gtctatccaa tcgctcaagc agctgatatc acagctttca aggctaatta tgttcctgtt
     9841 gggacagatc agaaaccaat gattgagcaa actcgtgaaa ttgttcgttc ttttaacaat
     9901 gcatataact gtgatgtctt ggtagagccg gaaggtattt atccagaaaa tgagagagca
     9961 gggcgtttgc ctggtttaga tggaaatgct aaaatgtcta aatcactaaa taatggtatt
    10021 tatttagctg atgatgcgga tactttgcgt aaaaaagtaa tgagtatgta tacagatcca
    10081 gatcatatcc gcgttgagga tccaggtaag attgagggaa atatggtttt ccattatcta
    10141 gatgtttttg gtcgtccaga agatgctcaa gaaattgctg atatgaaaga acgttatcaa
    10201 cgaggtggtc ttggtgatgt gaagaccaag cgttatctac ttgaaatatt agaacgtgaa
    10261 ctgggtccta ttcgtgagcg ccgtattgaa tttgctaagg atatgggaga agtttataat
    10321 atgattcaaa aaggtagtga aagagcgcgt gaagttgcgg gtcaaaccct atctgaggta
    10381 aaaggggcaa tgggacttca ttactttaac taagtttatt ttacaagaaa ctatcttttc
    10441 tatctcgaag aaaagatagt tttttattta cccctgtaac atttgacaaa tttttataga
    10501 atggtatgat agatacaata taaaaagagt caagctcaaa aagaaagaaa agaggaaact
    10561 tcgaatgtct aattgggaca ctaaattttt gaaaaaaggt tttacctttg atgatgtatt
    10621 gcttattcca gctgaaagtc atgtgttgcc taacgatgca gatttaacaa ctaaattggc
    10681 agataatttg actttaaata tcccaattat taccgctgcc atggacacag ttacagagag
    10741 tcaaatggcc attgctattg ctcgtgcagg cggtctcgga gttatccata aaaacatgtc
    10801 aattgctcaa caagcagacg aggttcgtaa ggtaaaacgt tctgaaaatg gagttattat
    10861 tgatccgttc ttcttgacgc ctgaacatac aattgctgaa gcagatgagc ttatgggtcg
    10921 ttaccgcatc agtggtgttc cagttgttga aacacttgaa aatcgtaaat tggttggtat
    10981 tttgacaaac cgagatcttc gttttatttc agattataat caaccaattt caaaccatat
    11041 gactagtgaa aatcttgtta ctgctcctgt gggtacggat cttgcaacgg ctgagagtat
    11101 tcttcaagag catcgtattg aaaaacttcc gttggtcgat gaagaaggca gtctttctgg
    11161 tttgatcact atcaaagata ttgaaaaagt tattgagttt ccaaatgcag ctaaagatga
    11221 gtttggtcgt cttctagttg caggtgcagt aggtgttact tcagatacat ttgaacgtgc
    11281 agaggctctt tttgaggcag gagcggatgc gattgttatt gatactgcac atggtcattc
    11341 tgcaggtgtc ttgcgtaaaa ttgccgagat tcgtgctcat ttcccagatc ggactttgat
    11401 tgctggaaat attgctactg ctgaaggtgc acgtgccctt tatgaagcgg gtgtagacgt
    11461 tgttaaggtt ggtattggac caggttctat ctgtactact cgtgtgattg ctggtgttgg
    11521 tgttccgcaa gtaacagcta tctacgatgc tgcagctgtt gcgcgcgaat atggtaaaac
    11581 gattattgct gacggtggga tcaagtattc tggagatatt gtaaaagcac ttgctgcagg
    11641 tggaaatgct gttatgcttg gatctatgtt tgctggaact gatgaagctc caggcgaaac
    11701 tgaaatcttc caaggacgta aattcaagac ttaccgtggt atgggatcaa ttgctgctat
    11761 gaagaaaggt tcaagcgacc gttatttcca aggttctgtc aatgaagcaa acaagcttgt
    11821 tccagaagga attgaaggtc gtgttgctta taaaggagcg gcagctgata ttgttttcca
    11881 aatgattggt ggtattcgct ctggtatggg ttactgtggt gcagctaacc ttaaagaact
    11941 acacgataat gctcaattta ttgaaatgtc tggtgctggt ttgaaagaaa gccatcctca
    12001 tgatgtgcaa attactaatg aggcaccaaa ttattctatg taaaaaacaa tgaaaagaac
    12061 tccagtgaaa acaggagttc ttttacaatg ttgtcaattt ccatttacag cagctttacc
    12121 atcctgaata gtgaagatac ttagattttc tggcagattt tgaagatggt ctaagcttgt
    12181 tgttgtgata aaggtttgga ttgattgaga aatcgtttct aataatttta actgtctagt
    12241 gttgtcaagt tcactcatca catcgtcaag cagtaatata ggagattctg tggtaatgct
    12301 ttccattaat tcgatttctg ctaattttat cgagaggacg agactacgat gttgaccttg
    12361 gcttccgaaa ctagcatcca tcccatttat ataaaaagaa atgtcatctc gatgaggacc
    12421 gacaccagta ttctttttaa ataaatctct ggatctactt ttttctaaag caattttgaa
    12481 agattcggat aagttttgtt tgtcagttat attgacagaa gattgatagg atattgacaa
    12541 ctcttcgatc tgattagaga gttcaaaatg tttcttacgc ccaaatgatt ctagtttttt
    12601 tatgaaatct aagcggtgat tcattacacg acatccataa tcaactagct gatcatctaa
    12661 cacagaaagg aatgtttcat ctattttttg agctgatttt aggtaagtgt ttctttgctt
    12721 taggatgtgg ttataattgg ttaagtcaga taaatagatt ggcttaattt gcccaagttc
    12781 catatcaatg aattttcgtc gaatcgaagg tgctccttta attagttgta aatcttcagg
    12841 agcaaataag acaacattca tgtgtcctac ataatctgaa aggcgtgcct gttttaagtg
    12901 attaactttt gttacacgac ctttttgtgt tagttcgatt tctaggggaa tggatccagt
    12961 ttttttctga acgagacctg aaagatgaag ttgttcctca tcaaaatgaa tgagattttt
    13021 atctgttcga gttcgatgac tacgcgttaa ggctaaaaaa tagatagcct ctaacatgtt
    13081 tgtttttcct tgtgcattac gtcccaaaaa gacattcaat ttaggattaa agtctatttt
    13141 cgtttctttg taattacgaa aagtcttgag agatagatgt tgtagccaca tgattatcta
    13201 ccagggaatc gtgaagcttg ttggctttta ggtgatgaag caggtttcga tttgtctttt
    13261 ttaactccct tattcatctt tttgacaagt ttagcgatcc gttctttttc aactttatca
    13321 gcttggtatt catcttgttc ttcagaagta ggttgtgtca acaagatgtc aatgttcatg
    13381 tcagggatgt caactttatc gccaatacga agtttttttc cacgacgact ctctaattcc
    13441 ctattaaagt aaacagaatg ttcagagaga aatgatttaa tagctcctcc gctatgtgta
    13501 attccaagtt ctttgagtag tgcttggagg gtaataaatt cttcaaataa tttgtattcc
    13561 ataattcacc tcaatctttg gtattatacc atattttcct aaaaatagtg agagagatag
    13621 ctagaaatgt aagcgatttt tatttcaaaa gtgttacagg gaacaagaaa atttcaggtt
    13681 ttcgtgatat aatagaagtc tgtatataag gaggtaaatc atggagttag tgcatggaat
    13741 ttcaacacat tttatccaat caaaaaagtt taaaacaaac aaaattaccg tgcgttttac
    13801 cgctccatta tcccttgata cgattgcagg tcacatgttg agtgcaagta tgctagagac
    13861 tgctaatcag atgtacccca cttctcaaga tttgaggaga cacttggcca gtctatacgg
    13921 tacagatatg tcaaccaatt gtttcagaag agggcaaagc cacattatag aattgacatt
    13981 tacctatgtt cgtgatgagt ttttaagtag gaaaaacgtg ctaacctctc agattttgga
    14041 acttgtaaaa gaaactcttt tttcacccgt agtagttgat aatgggtttg atccggcctt
    14101 atttgaaatt gagaaaaaac aattgctagc aagtttagca actgatatgg atgattcttt
    14161 ttattttgca cataaagaat tggataaatt gttttttcat gatgaacgtc ttcaattgga
    14221 atatagtgat ttacgaaatc gtattttagc tgaaactcca caaagttctt attcttgttt
    14281 ccaagaattt ttagccaatg atcgaataga tttctttttc ctaggtgatt ttaatgaggt
    14341 tgaaattcaa aatgtattag aatcatttgg ctttaaaggt cgaaaaggag atgtgaaggt
    14401 tcagtattgt caaccttatt ctaatatcct tcaggaaggt atggttcgga aaaatgtggg
    14461 acaatccatt ttggaattag gttatcatta cccttctaaa tatggtgatg aacaacattt
    14521 acccatgatt gtaatgaatg gtttacttgg tggatttgct cactctaagc tctttacaaa
    14581 tgtccgtgaa aatgctggat tagcttatac catttcaagt gagcttgatt tatttagtgg
    14641 attcttgagg atgtatgctg gtatcaatcg agaaaatcgt aaccaggctc gtaaaatgat
    14701 gaataatcaa ctgcttgatt taaaaaaagg ttattttaca gagtttgagt taaatcagac
    14761 caaggaaatg attcgttggt cgttgttact ttctcaagat aatcaatctt cattgattga
    14821 acgtgcttat caaaatgcct tatttggaaa atcttcagca gactttaaaa gttggattgc
    14881 aaagcttgaa caaattgaca aagatgctat ttgtagagta gctaataatg tgaaactaca
    14941 agcgatttac tttatggaag gaatagaatg acaaaggttg tttttgaaga aaaatactat
    15001 ccagctgtaa aagaaatggt ttatcgaact cgtttggcca acggattgac agttgctctt
    15061 ttgcctaaaa aggaatttaa agaggtttac gggagtgtca ctgtacagtt tggttcggta
    15121 gatacgtttg tcacagaagt tgacggagat gtaaaacaat atcctggagg aattgctcat
    15181 tttcttgaac ataaattatt tgagagagaa gattctagtg atttgatgtc ggcttttacg
    15241 agtctaggtg cagatagtaa tgcctttaca agctttacaa aaacaaacta tcttttttca
    15301 gcaacggatt attttttaga aaatttagat ttacttgatg aattggtaac atcagcacac
    15361 tttactgaag cttccattct gacagagcag gatattattc agcaagaacg agaaatgtac
    15421 caagatgatc cagattcgtg tttattcttt tcaactttag cgaatttgta tcctggtaca
    15481 cctttagcaa ctgatatagt tggaagtgag gagtccattt cccaaatcaa tctaactaat
    15541 ttgcaagaaa attttacaaa gttttacaaa cctgtaaaca tgtctctgtt tttagttggt
    15601 aattttgatg tggagcgagt acaggactat tttgaaagca aagaactgaa agattcagat
    15661 tttcaggaag tagcaagaga aaagttgttt ttacagcctg taaagccaac agatagtatg
    15721 agaatggaag tatcttctcc caaactagcg attggagtta gaggtaagcg agaagtttct
    15781 gaagcggatt gctatcgaca tcatatttta ttaaaattat tgtttgcaat gatgtttggt
    15841 tggacttcgg atcgttttca aaaatgttat gaatcaggta aaattgatgc atccttatct
    15901 ctggaagttg aagtaacaag tcgctttcat tttgtcatgt tgacaatgga tacgaaagag
    15961 ccagttgctt tgtctcatca atttaggaag gctattcgta attttacaaa ggatttagat
    16021 attacagagg aacatttaga tattatcaaa agagagatgt ttggcgaatt tttcagtagc
    16081 atgaactctc ttgaatttat tgcaacgcaa tatgatgctt ttgaaaatgg tgagacaatt
    16141 tttgatttgc cgaaaatttt acaggaaatt actttagagg atgtccttga tgctggacat
    16201 catttaatag atgatggtga catagttgat tttacaatat tcccatcgta gtaacctatt
    16261 ataatagaca ctagaaagaa gggatgacaa gtatgagaaa aaaaacaatt ggagaggttt
    16321 tacgattagc tagaatcaat cagggattga gtttagatga attgcagaaa aagacagaaa
    16381 tccagttaga tatgttggaa gcaatggaag cagacgattt cgatcaactt ccaagtcctt
    16441 tttacacgcg ttctttcttg aaaaaatatg catgggctgt tgagttagat gaccaaattg
    16501 ttttggatgc ttatgattct gggagtatga ttacttatga ggaagtagat gttgatgaag
    16561 atgagttgac aggtcgtaga cgttcaagta agaaaaagaa gaaaaaaaca tcatttttac
    16621 ctttatttta ttttatcctt tttgctttat cgattttaat ttttgtgact tattatgttt
    16681 ggaactatat tcaaactcaa ccagaggagc cttctctttc taattacagt gtggttcaat
    16741 caacaagttc aactagctct gttccccact cctcaagtag tagttcttct agtatagaat
    16801 cagctataag tgtatcaggc gaaggaaatc atgtagaaat cgcttataag acaagtaagg
    16861 aaacagttaa attgcaattg gcagtttcag atgttacaag ttgggtcagt gtttcagaaa
    16921 gcgaacttga gggcggtgta accttatcgc caaagaagaa aagtgcagaa gcaacagttg
    16981 caactaaaag tcctgtaaca attacgttag gtgttgtaaa aggtgttgat ttgacagtag
    17041 ataatcagac tgttgattta tcgaaattaa cagctcagac tggacaaatc actgtaacct
    17101 ttactaaaaa ttaaggaaaa acgaatgaaa aaagaacaaa ttcccaatct cttaacaata
    17161 ggtcgaattc tctttatacc tatttttatc tttattttaa cgataggaaa ttcgatagag
    17221 agtcatatag ttgcagctat tatctttgct gttgccagta ttaccgacta tttagatgga
    17281 tatttagctc gtaaatggaa tgtggtcagt aattttggta aatttgcaga tcctatggcg
    17341 gataagttac tagttatgtc ggcttttatt gtgttgattg agttaggtat ggctccggct
    17401 tggattgttg cagtgattat ctgtcgtgag ttagctgtga caggtttaag gcttttattg
    17461 gttgaaactg gtggaacaat tttagcagca gcaatgcctg gaaaaattaa aacttttagt
    17521 cagatgtttg ccattatttt cttgctatta cattggactt tgcttggtca agttctactt
    17581 tatgtagcct tatttttcac tatctactct ggctatgact atttcaaggg tagtgcctat
    17641 gtatttaaag ggacatttgg ttcgaaatga aatcaataat tgatgtaaaa aatctttctt
    17701 ttcgctataa agaaaatcag aactactacg atgtgaagga tattacgttt cacgtgaaac
    17761 gtggagaatg gctttcgatt gtagggcata atggtagtgg taaatcaacg acggttcgat
    17821 taattgatgg cttactggaa gcagaatccg gagagattgt aattgatggc caacgtttga
    17881 ctgaggaaaa tgtttggaat atacgtcgta aaatcggtat ggtttttcaa aatccagaca
    17941 atcaatttgt tggagcgact gttgaagatg atgttgcttt tggtttggaa aatcagggac
    18001 tttctcgtca agaaatgaaa aagagagtgg aagaagctct ggctttagtt ggcatgttgg
    18061 actttaaaaa gagagagcca gcgcgtctat caggtggtca aaagcaacgt gtggccattg
    18121 caggtgttgt agccctaaga ccagctattt taatcttaga tgaagcaacg agtatgttgg
    18181 atcctgaggg gcgtagagaa cttattggga cagtaaaagg aattcgaaaa gactatgata
    18241 tgacggtcat ttctattacc catgatttgg aagaagtcgc catgagtgat cgcgtattgg
    18301 tcatgaaaaa aggggaaatt gaatcaacta gtagtccaag ggagcttttc tctcgaaatg
    18361 atttagatca aattggatta gacgatcctt ttgctaatca attaaaaaaa tctttgagcc
    18421 agaatggcta tgatttacct gaaaattatt tgacagaaag tgagctagag gataagctat
    18481 gggaattgct ctagaaaatg tgaattttac atatcaagaa ggtactccct tagcttcagc
    18541 agctttgtcg gatgtttctt tgacgattga agatggctct tatacagctt taattgggca
    18601 cacaggtagt ggtaaatcaa ctattttaca actcttaaat ggtttattgg tgccaagtca
    18661 agggagtgtg agggtttttg ataccttaat cacctcgact tctaaaaata aagatattcg
    18721 tcaaattaga aaacaggttg gcttggtatt tcagtttgct gaaaatcaga tttttgaaga
    18781 aacggttttg aaggacgttg cttttggacc gcaaaatttt ggagtttctg aagaagatgc
    18841 tgtgaagact gcgcgtgaga aactggctct ggttggaatt gatgaatcac tttttgatcg
    18901 tagtccgttt gagctgtcag ggggacaaat gagacgtgtt gccattgcag gcatacttgc
    18961 catggagcca gctatattag tcttagatga gccaacagct ggtctagatc ctctagggag
    19021 aaaagagttg atgaccctgt tcaaaaaact ccaccagtca gggatgacca tcgtcttggt
    19081 aacgcatttg atggatgatg ttgctgaata tgcaaatcaa gtctatgtaa tggaaaaggg
    19141 acgtttagta aaggggggca aaccaagtga tgtctttcaa gacgttgttt ttatggaaga
    19201 agttcagttg ggagtaccta aaattacggc cttttgtaaa cgattggctg atagaggcgt
    19261 gtcatttaaa cgattaccga ttaagataga ggagttcaag gagtcgctaa atggatagta
    19321 tgattttggg gcgttatatc ccaggggatt cgattgttca ccgattggat ccacgtagca
    19381 aattgcttgc tatgatgcta ctgattttga ttgtgttttg ggctaataac cccttgacga
    19441 atctgattct ttttatagcg acagggatat ttattgcctt gtcaggagta tctctttcat
    19501 tttttattca gggcttgaag tctatgtttt tcttgattgc cttcacaact atttttcaac
    19561 tatttttcat ttctaatggg aatgttttat ttgagttttc gtttgtgaga atcacggatt
    19621 atgctttgca acaagctggg attatttttt gtcgctttgt attgattatt ttcttttcaa
    19681 ctttgttaac cttaacaacc atgcctttaa gtttggcatc agctgtcgaa gctttattag
    19741 cacctttaaa gcgtgtgaaa gttccagttc atgaaattgg attgatgctg tctatgagtt
    19801 tgcgttttgt cccaaccttg atggatgata cgactcggat tatgaatgca cagaaagctc
    19861 gtggagtgga ttttggagaa ggaagcatcg ttcaaaaagt aaaggcgatg attcccattt
    19921 tgattcctct ttttgcgaca agtttaaaac gtgcagattc cttggctatc gctatggaag
    19981 cgcgtggcta tcagggtgga aaaggcagaa gtcaataccg acaattgaaa tggactctaa
    20041 aggatacgct gaccattctt gttattctcg tacttggttg ttgtttattt ttcttaaaat
    20101 cttagtagct ttcaggaatt gataaaaagt tactgtaaca gtttttgata taaaggtagg
    20161 gatatgaacc gttttaaaaa atcaaaatat gtcattattg tttttgtcac tgttctgctt
    20221 gtgtcagctc tcttagcgac gacttattca agtacaattg tgacaaaatt aggagatgga
    20281 atctcattgg ttgatagagt tgtacaaaaa ccttttcagt ggtttgattc tgtcaaatca
    20341 gatttggctc atttgacacg aacatataat gaaaatgaaa gtttgaagaa acagctttac
    20401 caattagaag ttaaatcaaa tgaggtggaa agtttaaaga cagaaaatga acaactgcgc
    20461 caattgcttg atatgaagtc taaattgcaa gccacaaaga ctttagcagc agatgttatt
    20521 atgcgttctc cggtatcttg gaagcaggag ttgaccttag atgcaggtag atcaaaaggt
    20581 gcttctgaga acatgttagc tattgcaaat ggtggcttga ttgggagtgt ttcaaaagta
    20641 gaggagaact ctactatagt caaccttctg acaaatacgg aaaatgctga taagatttct
    20701 gttaaaattc aacatggctc tactacaatt tatggaatta ttattggcta tgacaaggaa
    20761 aatgacgttc ttaaaattag ccaattaaat agtaatagcg atattagtgc gggagataag
    20821 gtgactactg gtggattagg aaactttaac gttgctgata ttcctgttgg tgaagtggtt
    20881 gccacaacgc atagtacaga ctatttgaca cgagaagtaa ctgttaaatt gagtgcagat
    20941 actcataatg tagatgtgat agaattagtg gggaattcat aatgagacag ttgaagcgag
    21001 ttggagtatt tttattgctt cctttctttg ttctaattga cgcccatatt agccagcttc
    21061 tgggctcatt tttcccccat gtacatttgg ctagtcattt tctttttcta tttctcttat
    21121 ttgagacgat agaagtatca gagtatctct acctagtcta ttgttttgtt ataggcttgg
    21181 tttatgatgt ttactttttc catctaatag gaattacaac tctcttattt atcttattgg
    21241 gagccttcct tcataaattg aatagtgtta ttttgttgaa tcgttggaca agaatgctag
    21301 ctatgattgt gctgacattc ctgtttgaaa tgggtagtta tcttttggct tttatggtag
    21361 ggttgacagt agatagcatg tcgattttta tagtctatag cttggtaccg acgatgattt
    21421 taaatttttt atggattact gtttttcaat ttatttttga aaaatattat ctataagaac
    21481 gacatataaa tgtaacaaag gcgtaatatt tattaggcct ttttttggta tactagtatt
    21541 gtctttaaaa gaaggagtat ctacgtaata tgaagaaaaa aatcttagcg tcacttttat
    21601 taagtacagt aatggtttct caagtagctg ttttaacaac tgcgcatgca gaaacgactg
    21661 atgacaaaat tgctgctcaa gataataaaa ttagtaactt aacagcacaa caacaagaag
    21721 cccaaaaaca agttgaccaa attcaggagc aagtatcagc tattcaagct gagcagtcta
    21781 acttgcaagc tgaaaatgat agattacaag cagaatctaa gaaactcgag ggtgagatta
    21841 cagaactttc taaaaacatt gtttctcgta accaatcgtt ggaaaaacaa gctcgtagtg
    21901 ctcaaacaaa tggagccgta actagctata tcaataccat tgtaaactca aaatcaatta
    21961 cagaagctat ttcacgtgtt gctgcaatga gtgaaatcgt atctgcaaac aacaaaatgt
    22021 tagaacaaca aaaggcagat aaaaaagcta tttctgaaaa acaagtagca aataatgatg
    22081 ctatcaatac tgtaattgct aatcaacaaa aattggctga tgatgctcaa gcattgacta
    22141 cgaaacaggc agaactaaaa gctgctgaat taagtcttgc tgctgagaaa gcgacagctg
    22201 aaggggaaaa agcaagtcta ttagagcaaa aagcagcagc tgaggcagag gctcgtgcag
    22261 ctgcggtagc agaagcagct tataaagaaa aacgagctag ccaacaacaa tcagtacttg
    22321 cttcagcaaa cactaactta acagctcaag tgcaagcagt atctgaatct gcagcagcac
    22381 ctgtccgtgc aaaagttcgt ccaacataca gtacaaacgc ttcaagttat ccaattggag
    22441 aatgtacatg gggagtaaaa acattggcac cttgggctgg agactactgg ggtaatggag
    22501 cacagtgggc tacaagtgca gcagcagcag gtttccgtac aggttcaaca cctcaagttg
    22561 gagcaattgc atgttggaat gatggtggat atggtcacgt agcggttgtt acagctgttg
    22621 aatcaacaac acgtatccaa gtatcagaat caaattatgc aggtaatcgt acaattggaa
    22681 atcaccgtgg atggttcaat ccaacaacaa cttctgaagg ttttgttaca tatatttatg
    22741 cagattaatt tacagaggga ctcgaataga gccctctttt caggttttac cgtgacaatc
    22801 cctattaaaa attatatcaa aatagcttga aaatattgga aaagtatggt agaatgaaaa
    22861 ttgtcgtgtg aacgataata ctcattcttg atgaattgtg aagcagttgc ccttgggtcg
    22921 ttttgcgagt tgaagtcaag aagaggaaaa aaacaaaaag gagaaatact catggcagta
    22981 atttcaatga aacaacttct tgaggctggt gtacactttg gtcaccaaac tcgtcgctgg
    23041 aatcctaaga tggctaagta catctttact gaacgtaacg gaatccacgt tatcgacttg
    23101 caacaaactg taaaatacgc tgaccaagca tacgacttca tgcgtgatgc agcagctaac
    23161 gatgcagttg tattgttcgt tggtactaag aaacaagcag ctgatgcagt tgctgaagaa
    23221 gcagtacgtt caggtcaata cttcatcaac caccgttggt tgggtggaac tcttacaaac
    23281 tggggaacaa tccaaaaacg tatcgctcgt ttgaaagaaa ttaaacgtat ggaagaagat
    23341 ggaactttcg aagttcttcc taagaaagaa gttgcacttc ttaacaaaca acgtgcgcgt
    23401 cttgaaaaat tcttgggcgg tatcgaagat atgcctcgta tcccagatgt gatgtacgta
    23461 gttgacccac ataaagagca aatcgctgtt aaagaagcta aaaaattggg aatcccagtt
    23521 gtagcgatgg ttgacaccaa tactgatcca gatgatatcg atgtaatcat cccagctaac
    23581 gatgacgcta tccgtgctgt taaattgatc acagctaaat tggctgacgc tattatcgaa
    23641 ggacgtcaag gtgaggatgc agtagcagtt gaagcagaat ttgcagcttc agaaactcaa
    23701 gcagattcaa ttgaagaaat cgttgaagtt gtagaaggtg acaacgctta atttatacaa
    23761 atagtaatta cctaggaggg cggggcttag cccggctctc ctattttcaa aaaatatagg
    23821 agaattaaaa tggcagaaat tacagctaaa cttgtaaaag agttgcgtga aaaatctggt
    23881 gccggtgtta tggacgctaa aaaagcgctt gtagaaacag acggtgacat cgaaaaagcg
    23941 attgaattgc ttcgtgaaaa aggtatggct aaggcagcta agaaagctga ccgtgttgct
    24001 gcagaaggtt tgactggtgt ttatgttaac ggtaatgttg cagcagttat tgaagtaaac
    24061 gctgaaactg acttcgttgc aaaaaacgct caattcgttg aattggtaaa tactacagct
    24121 aaagtcattg ctgaaggaaa acctgctaac aatgaagaag ctcttgcttt gataatgcct
    24181 tcaggtgaaa ctcttgaagc tgcatacgta tctgcaacag caactatcgg agagaaaatc
    24241 tcattccgtc gctttgcatt gattgaaaaa acagacgcac aacactttgg agcataccaa
    24301 cataacggtg gacgtatcgg tgttatttca gttgttgaag gtggagacga agcacttgct
    24361 aaacaattgt caatgcacat cgcagcgatg aaaccaacag ttctttctta caaagaattg
    24421 gatgagcaat tcgttaaaga tgagttggca caattgaatc acgttatcga ccaagacaac
    24481 gaaagccgtg caatggttaa taaaccagct cttccacact tgaagtatgg atcaaaagct
    24541 caattaactg atgatgttat tgctcaagct gaagctgaca tcaaagctga attggctgca
    24601 gaaggcaaac cagaaaaaat ctgggacaaa attattccag gtaaaatgga tcgcttcatg
    24661 cttgataaca ctaaagttga ccaagcttac acacttcttg cacaagttta catcatggat
    24721 gacagcaaga cagttgaagc ataccttgaa tcagttaacg cttcggtagt tgagtttgct
    24781 cgctttgaag ttggtgaagg tatcgagaaa gctgcaaacg acttcgaagc tgaagttgca
    24841 gctacaatgg cagcagcctt gaataactaa taatagaaag gaagcaattt gcttcctttt
    24901 ttggactctt tgtcaactgt agtgggttga aaaaaagcta agct
//
LOCUS       DAVLHB010000030        23786 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLHB010000030 DAVLHB010000000
VERSION     DAVLHB010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.030"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(20..616)
                     /locus_tag="VXE36_001336"
     CDS             complement(20..616)
                     /locus_tag="VXE36_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0779637.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(613..1095)
                     /locus_tag="VXE36_001337"
     CDS             complement(613..1095)
                     /locus_tag="VXE36_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEV0779638.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(1092..2228)
                     /locus_tag="VXE36_001338"
     CDS             complement(1092..2228)
                     /locus_tag="VXE36_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779639.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            complement(2235..2531)
                     /locus_tag="VXE36_001339"
     CDS             complement(2235..2531)
                     /locus_tag="VXE36_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV0779640.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(3061..3954)
                     /locus_tag="VXE36_001340"
     CDS             complement(3061..3954)
                     /locus_tag="VXE36_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0779641.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(4708..4938)
                     /gene="blpU"
                     /locus_tag="VXE36_001341"
     CDS             complement(4708..4938)
                     /gene="blpU"
                     /locus_tag="VXE36_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0779642.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(5141..5431)
                     /locus_tag="VXE36_001342"
                     /pseudo
     CDS             complement(5141..5431)
                     /locus_tag="VXE36_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(5477..5710)
                     /locus_tag="VXE36_001343"
     CDS             complement(5477..5710)
                     /locus_tag="VXE36_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0779643.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(5716..6708)
                     /gene="plsX"
                     /locus_tag="VXE36_001344"
     CDS             complement(5716..6708)
                     /gene="plsX"
                     /locus_tag="VXE36_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0779644.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFVVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(6705..7475)
                     /gene="recO"
                     /locus_tag="VXE36_001345"
     CDS             complement(6705..7475)
                     /gene="recO"
                     /locus_tag="VXE36_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0779645.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(7472..8641)
                     /locus_tag="VXE36_001346"
     CDS             complement(7472..8641)
                     /locus_tag="VXE36_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0779646.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            8790..9800
                     /locus_tag="VXE36_001347"
     CDS             8790..9800
                     /locus_tag="VXE36_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0779647.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(9991..10428)
                     /locus_tag="VXE36_001348"
     CDS             complement(9991..10428)
                     /locus_tag="VXE36_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0779648.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(10513..13146)
                     /gene="polA"
                     /locus_tag="VXE36_001349"
     CDS             complement(10513..13146)
                     /gene="polA"
                     /locus_tag="VXE36_001349"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0779649.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            13402..13752
                     /locus_tag="VXE36_001350"
     CDS             13402..13752
                     /locus_tag="VXE36_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0779650.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIHQREGDTH"
     gene            13967..14083
                     /locus_tag="VXE36_001351"
     CDS             13967..14083
                     /locus_tag="VXE36_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0779651.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            14076..14309
                     /locus_tag="VXE36_001352"
     CDS             14076..14309
                     /locus_tag="VXE36_001352"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779652.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEDLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            14436..14717
                     /locus_tag="VXE36_001353"
                     /pseudo
     CDS             14436..14717
                     /locus_tag="VXE36_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(14850..15818)
                     /locus_tag="VXE36_001354"
     CDS             complement(14850..15818)
                     /locus_tag="VXE36_001354"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0779653.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(15963..16778)
                     /locus_tag="VXE36_001355"
     CDS             complement(15963..16778)
                     /locus_tag="VXE36_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV0779654.1"
                     /translation="MYEEKQYFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     STFLNAFESAIVAPLVEESLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(16799..17296)
                     /locus_tag="VXE36_001356"
     CDS             complement(16799..17296)
                     /locus_tag="VXE36_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0779655.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(17369..18730)
                     /gene="radA"
                     /locus_tag="VXE36_001357"
     CDS             complement(17369..18730)
                     /gene="radA"
                     /locus_tag="VXE36_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0779656.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLVKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(18744..19259)
                     /locus_tag="VXE36_001358"
     CDS             complement(18744..19259)
                     /locus_tag="VXE36_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0779657.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(19261..19704)
                     /locus_tag="VXE36_001359"
     CDS             complement(19261..19704)
                     /locus_tag="VXE36_001359"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0779658.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(19764..19857)
                     /gene="ffs"
                     /locus_tag="VXE36_001360"
     ncRNA           complement(19764..19857)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXE36_001360"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(19890..20357)
                     /locus_tag="VXE36_001361"
     CDS             complement(19890..20357)
                     /locus_tag="VXE36_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0779659.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(20558..21844)
                     /locus_tag="VXE36_001362"
     CDS             complement(20558..21844)
                     /locus_tag="VXE36_001362"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0779660.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(22075..22311)
                     /locus_tag="VXE36_001363"
     CDS             complement(22075..22311)
                     /locus_tag="VXE36_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0779661.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            22577..23373
                     /locus_tag="VXE36_001364"
                     /pseudo
     CDS             22577..23373
                     /locus_tag="VXE36_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23408..>23786)
                     /locus_tag="VXE36_001365"
     CDS             complement(23408..>23786)
                     /locus_tag="VXE36_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0779662.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEEMVTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAYIKK
                     NLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         7507 a         5463 c         3812 g         7004 t
ORIGIN      
        1 cattaatttg tataaactat tatttgtttg aaatttcata aacccgtcct tcctctatta
       61 aaatcctttg agatttgcta atcaattctt gattcaataa attatgagat acatatataa
      121 tagtagagct ttctttcatg gaaattaagc gtttagcaat catatcaata cttcttgcat
      181 ccactgttga taaagtctca tcaataaaaa tataatccca atttttagca aaaattaagg
      241 ataagcctaa tttgaatttt gttccagtag atgctgtcat atagttatct ccgattttat
      301 tatcaaaaaa agtattaatt tgttctttat cctcaaatga tagatggatt tgaaaagaat
      361 cacacaacaa ctgcaaattt tcttctatag taaatggaac aaccccaagc tgattggtat
      421 caaggtatag tacatctttg gagacacaat tctttaaacc actatcaaaa gtctctagcc
      481 cagctaaaag ttgtagaagg gtgctctttc ctgaaccatt ctctccttca actctgtaaa
      541 ttcccttatc aatctctagt gatatatttt tcaatataca tttatcataa cttttagatt
      601 cattttcaat tttcataatt taattccctc tatcaacgct gctaaaatta ataaaagata
      661 agaaatgata taccatttta aattactttt tatataaata agtatatttt taattcccct
      721 atccttcaat aatcggtata aaagatactg actcatacct tgataccaaa taaaattcgg
      781 tatttcaata agagcatgag gtaatattcc ttttattgta gctactattc caatcatctg
      841 accagatata cccaattgta ttcctaaaga tagcaaatca aaaagttgca ataagggcga
      901 aatcggaaaa cagaatagat atagcaaaaa atttgtagaa tttgcctgta aaactgtcaa
      961 tgtaaattgt aattccagtt tcggaggtat agtagcaaaa gtctcatttt ttaatataaa
     1021 gcttaaaagt aaacctagta aaaaacagac tatacaaaat aacacatagt aaatcagaaa
     1081 accacttttt ctcatctaat gccccctact aaaattacaa atattatcag aaaacaatat
     1141 aaaaccagaa aactccatct caataaacta actgtacctt taattaaaaa tagagctttc
     1201 ttataataga cataggctat aaaataattg aatggaatca ataacaaatt caacaaaata
     1261 ctttttatat cattactata acttgtcacc ggaatcaaac ataacaacaa tgaaaattgt
     1321 aagaaagaga ttaaatgcgt caacatcatt agttgtgcat tcttaaaaaa gaaattcatt
     1381 ttagaatgat taagagcaga taattgaagt aaagctagat ctaccccaat tgaggattta
     1441 tgattcccta ttattgcctc cattaatgta atatatattg aggtataaag aaataatatt
     1501 ggtatttttg tgtcatcaat tgataacatc gtcatcatat accaaaatag ataggaaaga
     1561 agaatactaa tcaaaataaa agaaaaagtt aaccctttat ttaaccaaca aaaacgaagc
     1621 aatataaata gactgctacg aaatcttttt tgactcattc gactgctttt aaaatagaaa
     1681 ttactcgcat gattatctaa tatccccatg actaaaataa aataattgag tagtatgaca
     1741 taaattacaa cttgtccttg ttctatagac aatagtccta tagataaaaa taagaacaat
     1801 ttacttataa ttgaaaacaa actaggtaga attaaagaaa taatttgaat agctatcaaa
     1861 caaagagtaa tggataaata aaaatatcca ataatatcta gaaaatacaa aataaataaa
     1921 taaatgaatg attgtaaaat ttggaaagaa taatatttct tgacaatggc aagaagatag
     1981 agaaaaatat agtttttcct tatatagaaa gtatttattt ttttactttg gataggcagt
     2041 ttcatattat aacgattcaa agtagcgtaa tctactacca aaaaaagtaa aaataatttc
     2101 ccttgaaaag gaagatagct tttaaaatag attgacaaac ttatgataac aaaaaacaaa
     2161 agggttatcc caataaaatt aagataacct aaaatacttt cacattcttt tttagaaagt
     2221 attttcatct agttctacca tagagctgct ttagcagcac ctttcttttt caatatataa
     2281 agaactgttg ctgcaatacc cgaaccaata gaacctactc ctgtgattgc acctacaatt
     2341 gaaattactg ctgtaactgt actataagca ctaatcaaat tgactacagt agcagcagct
     2401 tttgtcgaaa ttcctaatgt cccagccaac ataggaaaag aaacaacacc taagcttaac
     2461 caactaatga ctgctaacat tgctgaaaca ataagaaatt tattatgaaa ttccattctt
     2521 ttagatttca ttttagtgta ctccttttgt atattatgta tgttttattg agagttaatt
     2581 cgcacatgtt gtattcctaa ctctcttcaa atgttcgtct atattttata ctacttttat
     2641 taacatatct ataataaata aattactact acattttcct agattatcaa attactttta
     2701 tatcactaag actcaataaa agataatgtc tatttaactt ttatacgatt actacctctt
     2761 tttagtttac acttcctaca tcataaataa acatactcaa ccctcacaat ctccaaataa
     2821 ctcttctata tcattgaaaa ttgagtttca tcctctatac taatgtagga cattccttta
     2881 atccaatata agaatacctt gttccattaa tctctacccg atattataga tagaaccaaa
     2941 ttcctatact taaaaggaca aataacgttc caaccataat aaacctcctt tctttttgag
     3001 aacgttttct ttataggttt agtatagcaa aaacatgaaa aaaacaacat gacttagaag
     3061 tcaggttgtt gggaaatcta tctgtttttc tgctaaaatt ctctgaacta atacctgatc
     3121 gtctagcaat tctgctagag aaatcgcctt ttcatagaaa ctttctgcct ctaaaatatt
     3181 cttgtctaca aataaagcat attttgcctt tagcaaaaat agatgaggtc ggtaaaaaac
     3241 atgtcttgtt ttagcaataa ttttctcaaa tgtttgaata tatatcagac tatcttctgt
     3301 ctgaatttgg ataaataggc tcagaagaac tttttccatt tgaactaggc tagccttatc
     3361 ttcatattct gaacatagca atactttttg agctaactcc tcaaaatgtt ctttatcttc
     3421 taatcccata gcacaacaaa agaaatacaa ttcaataatc aacaaatcat ttacagaaaa
     3481 atatttcttt tttaataact gctggaaata ttcttccact aaccctaaac cgtaggtcac
     3541 atctgaacta ccataaatat caaaacgagc ttgtgtcaca tccacaatta actgctcttc
     3601 ctcaggcaaa ttctcataat agttttcata tatttcctca agtatagctt cttttcgttc
     3661 gattcttccc ttatcagcgt aggtttgaga atgaatcagc tcatctttga gttttaggaa
     3721 tccttttgga atctctataa ccttaacatc cacaatattc tgtaatgata ctccaagttt
     3781 atccgcaatc aataataatt taggaagtgt tgctaaagct tgcccatttt caatacgtgc
     3841 tagctgacga atcgtcaact ctgattcatc accacaaata tctatctgag tttttccaca
     3901 agatcgccta atagttttga ttttataacc aatttcacgt ttcaactcat ccatagtaat
     3961 actccttaag ttgattacaa agatttcttt ttcttcctaa ttcttttgtc aatcatatat
     4021 aaaacgataa gcgaaaacag cggtagaaca atataactct tttcactcat tatcagctga
     4081 aatcccaggg ttgctagtat cttaaagatg aaaatattca tcaaaaatag aaaaacaaat
     4141 actaaaaaat attttaaaac cttcttcatt tcttttcttc aactttccta atttctacac
     4201 ctattttatc gaaaatatat ataaaactcc aaataaacac ttcgactgca ctttttttgg
     4261 caaaaaatag acagaacaaa catcctacct actaaaaata tgatatgaaa ggaaaatgat
     4321 tttttactga caccctaggc aagcttggga caaataaatc attgatagca acatttacga
     4381 catcctattt aaagttcctt caatttctaa tgtccccgct atttctaagc cacctctggt
     4441 atgatctatt cctagtcaga atagataaca ccgttctaaa ttacgattca tagttactcc
     4501 ttttttgact cgttactata agactcctat ttacatgcgc aaaataattt tgattcagat
     4561 tcatcattta tagttttgat tattttttaa cagatttttc tgttttcttc tccgaagact
     4621 ttaaaaattt ttttctaatt aaatcatcca tataaggacc aaatatacca actactaaac
     4681 caataataaa acttttaaaa tccataatta ccaccaacat gtcgctgcat aggccacacc
     4741 tccaagtata gctcctccca cagcaccagt tgctgcacct tgccatgttc ttgttttaat
     4801 tcctagctga agacctcgta ctgctcctcc tccaacacct gctttggcaa aatctcccca
     4861 attgcatccg ccaccttcaa cgcaagcaag catctcagta tccataattt caaattgtga
     4921 catctttttt gtattcataa cgaatacctc ttttttattt ttaatatttg tcttgttaca
     4981 aacttgacaa gtttagtata acagtatcta ttaatttttt tcatccaaat cttgaattgg
     5041 catcgaaacg tcttgaatta gcttttttgt ttcaaaatca tctctatttt taaaaaagat
     5101 gttttctaat cactttttta ctattagact tcctgcaaaa ctagaatcct agttcatgat
     5161 tgataatacc agcaatcaaa ttcattcgta atccgaagcg tttacgatga tttcgatagg
     5221 ttgttgaaaa cattttaaac gtttttactt tggcaaagat attctcaacc ttgcttctct
     5281 ccttagatag cgcatgatta caggctttat cttcaactgt tagcggcttg agtttgcttg
     5341 atttacgtgg agtttgtgct tgaggatata tcttcatgag cccttgataa ccactgtcag
     5401 ccaagatttt tccagcttgt ccgatatttc tcatttctaa aaaccatcta cttccgttga
     5461 cttggaactc cgattgctat tttccttgaa tgattttaac cacatctcct acgttttgga
     5521 gttggtcaat ttcttcatcg ctgatttcga tactaaattc atcttccaga gtcaagataa
     5581 actccatcaa gtcaacagaa tccgcatcca aatcgtcttt cagactcaag gattctgtca
     5641 cgacaaagtc ctctccctgt cgctcttgga taatggtcac aatacggtca aaaatttctt
     5701 tttctgtcat ctcttttatt ctcctgaaaa ttcacgcgca gtctgggcaa ccacgtctgt
     5761 ttctagcatg gtacggatct gacgaatcgt actataaaca gccttggcat cgcttgagcc
     5821 atgagtcttg acaacaggtg ccttaacacc aaacaagacc gctccaccaa catctgaata
     5881 attgagctgt tttttcaaac ctctgaggct gtccttgaga aggagggcac ctagtttcgc
     5941 tcgaagacca ccacctgtaa tagctgtctt gagcaagccc atgattccca tagctgtccc
     6001 ttcgatggat ttgagcacag cgtttcccgt gaaaccatct gccacaacaa catctgcaac
     6061 gccattcatc aaatcacgcg cttccacgtt tccgataaag ttcaaacttt catcagccgc
     6121 cagtaattca taagtttcct tacgaagcgg gtcgcccttg ctactctctg ttccgttgtt
     6181 gagcaaacca acgcgtggtt gcgcaatgcc acggacattt ttagcataga aggaacctag
     6241 aaccgcatat tgatggaggt gctgggctgt attttctgca ttggcaccaa ggtctagcat
     6301 gtcaaaacct tttccatcaa cggtaggcaa ggtagacatg agtccaggac ggtcgatatt
     6361 cttgatacga cccacgacga agaatcctgc tgccaacaag gcacctgtat tcccagccga
     6421 aaggacagcg tctgcttcac catctttgac agccttggct gccaatacca tactggcatt
     6481 tttcttattc ctaatagctc tcgtaggttc atcatccgaa tcaatcttct catccgtatg
     6541 gataatgctg acgcgctctg tcgctgtcag atattgcttg attttagctt catctccgta
     6601 aagttgaacc tcgatatctg aaaagtcaga tagggcttga ttgacaccct caacaatggc
     6661 ctgaggtgcg taatcgcccc ccatggcatc tactgcgatt tttttcattt cttttcctct
     6721 tttagtaatt gtccccagtc tgctagggaa tcaataaatt tctttgattt taggtgaatc
     6781 ccaacgtact cttcatataa ttgatccata aattggcgta gctcttgctt gattccaggc
     6841 ttgagcgaaa tggtctccaa agtctcaaaa tcaatagctt gaaattgatt gagcagatag
     6901 gggatattgg gattgagatg acaacgtctc ttatcctcat gataatgctc tggacagagg
     6961 caggctccat atttgaaaga aaagtcaaaa gcctgaccaa cccgatggca gaagacacac
     7021 tcattaaaat tgaggctgat tccaaatcga gtcaaaattt gaatttcaaa aatattggtc
     7081 aaaacctgat aatccaagcc tgcttccatc aactccaaag tcttttgcaa aaaagcaaac
     7141 aagggagcat cctgctgatt gtcctgcaaa ctagcatctg caagagctgc cacataggtc
     7201 gcataggcca tgacaaagag gtcactatta atcttgggaa aagtcatgac ctcatgatag
     7261 tcttcgatgt aactgagtcc gtcatcattg attcgcaaga gaaatcgtgc cagcaccaag
     7321 ggctgaataa caggcgccag cttagactga ccagcgtgtt tgacaaaaaa catgcgtttg
     7381 ccaacctgct ctgtaaaaat tttgacgagc ttgtcatcct cacgaaaatt gcgattgtaa
     7441 agcaccaagc cttgactcgt gatagactga atcatgcttc tctcatgtac tcctcaagtc
     7501 gtttcatggc ttctttgata gtctccatgc tggctgcata agataggcgg acgtagcctt
     7561 ccccgtaacg tccaaaggct gcaccaggga taaaggcaac ggccttcttc tgagcaaaat
     7621 ccttcagaaa agcaaaggag tcttgattgt agcccgctgg aattttagca aaaatataga
     7681 aggcaccgtc tggtttgata atctcaaaac caagagcagt cattttttcg atgatatagt
     7741 cccgacgctg gatatattcc ttcttcatgg gctccgcatc atttttacca gccgtcaagg
     7801 cttctaccgc agcatgttgc gccatggtat ttgcggcagt gaccaagtac tggtgactct
     7861 tgattaactg ggctgtgaag gtcgcaggag cgaaaatcag ccccaaacgc caacctgtca
     7921 tggcatgcga tttagacaaa ccattgataa taatagcctg gtctctcaac atcgttccta
     7981 gagacacatg ggcttcgcct gtgtaggtca attctgagta aacctcatca cagacaacaa
     8041 aaacttcgta cttgcgtaaa acagctgcca aggcctctaa ctgctctcga ctgtaggtaa
     8101 ttcctgtcgg attggctgga tagttgagaa taaccgcctt gagcttatca ccctgctcca
     8161 aaatggcctt ctccaacatc tcaggagtca agacaaaacc attttcagtc gtatcaatct
     8221 caacaatttc tgccccaact aagttaacaa tcggttcata acccggataa gcaggagctg
     8281 gcaaaagtac cttgtctccc tcttccaaaa tagccgtcaa agtcgcagat aaagcctctg
     8341 tcgccccaat tgtaaccaag atttcatttt caggagcata gtccagttgg tacttttcct
     8401 taacaaagtc actggctgcc tgacgtagag tcagcagacc actcatccct gtatagtagg
     8461 attggttctg atcaatcgct cgcttggccg cctccttgac atggtctggc gttgtaaaat
     8521 caggttcccc caaggtcaaa cgcaagaccc caggaatctc cgaaataacc tggtcaaact
     8581 gacgaatcaa cgaaacttga attttatcta actgtttatt aaagcgctta gttaagtcca
     8641 tagatacctc ctactttcaa aacgtatctc tattatacta caaaagcccc ccgaccgcaa
     8701 aaatacatta gagaatagct ttccactttc tattttactt ttcctgttta taggtctata
     8761 atggtaacag attctatttg gaggttttta tgtcatttct atcaaaaaat ggagcaggta
     8821 tcttggcctg ccttctcatt tccatcctat cttggtactt aggaggattc ttccctgtga
     8881 ttggcgcgcc cgtttttgcc attttcatag gcatgctcct acatcccttt ctctcgtcct
     8941 ataaacaact ggatgctggt ttgaccttta gttccaagaa gttgctccaa tatgccgttg
     9001 tcttgcttgg ttttggtctc aatatctcgc aggtcttcgc agttggccaa tcttcactcc
     9061 ctgtcatcct gtccactatc tcaatagctc tgattattgc ctacctcttc cagcgtttct
     9121 ttgcactgga tacaaaactg gctaccttgg ttggagtagg ttcttctatc tgtgggggtt
     9181 ctgccattgc agcgacagcg cctgttatcc atgctaagga aaaggaagta gcccaagcca
     9241 tttccgttat ctttttcttc aatgtcttgg ctgcgctcat ctttccaacc ctcggcacct
     9301 ggcttcatct atccaatgaa ggcttcgccc tctttgcagg gactgcggtc aacgacactt
     9361 cctctgtaac ggctgccgcc agcgcttggg acagtcttta ccaaagcaat accctcgagt
     9421 ctgcaaccat tgttaaactc acacgtactt tggccattat ccctatcacg ctctttctat
     9481 cctactggca aagtcgccaa caagaaaaca agcaaagcct acaactgaaa aaagtcttcc
     9541 cactttttat cctttacttt atccttgcct ctctcctcac tacactactc acctctctag
     9601 gtgtgtccag tagtttcttt acccctctca aacaactctc taaattcctt attgtcatgg
     9661 ccatgagtgc tatcggtctc aaaaccaatc tggtcgctat ggtcaaatcc agtggaaaat
     9721 ccattcttct tggagccatc tgctggattg ccatcatcct caccactctt ggtatgcaga
     9781 cccttatcgg cattttctaa cactcttcga aaatctcttc aaaccacgtc aacgtcgcct
     9841 tgccgtatat atgttactga cttcgtcagt tctatctgca acctcaaaac ggtgttttga
     9901 gcagcccgcg gctagtttcc tagtttgcta gtgtgctctt tgattttcat tgagtataac
     9961 acaaaaggta gcccatcagc tacctttttc ttatgcttcc tcaatcaagc gagtatgttc
    10021 tctcttgata cagcgattca tcacgatatc atcacatcca ccatcacgca aaatctcttt
    10081 cgcttctaaa ctttcaagtc ctagctgtgc ccaaaaaatc ttggcatcag ctttgagaaa
    10141 atcacgcgcc acatcgggca gaaattcact gcgacgataa acattgacaa tatctacagg
    10201 aaaaggaatt tcagcgaggc tagcataagc cttttcaccc aagatttcgc cacctgccgc
    10261 cttgggattg actgggatga ttttatagcc ccgagcctgc atttcctttg ttactcgatt
    10321 gctggttgtt tcttcacggt cagacaaacc caccacagca agggttttac tcgttgcgag
    10381 atactgacga atcacaccat cacttggatt gataaattct tgactcatag aaaacctcct
    10441 ttttcatcag tatagcacat tttgaaaagg tttgcagaat tctactacaa aaaaggagga
    10501 ctagccccct ttttatttag cctcgtacca ggttgcccct tcattctcat ctgcgataag
    10561 aggaacactg agttgaatgg cttcttccat ggtttgtttc accaattttt ttatctctac
    10621 caattcagat ttaggcactt caaggacgat ttcatcgtgc acttgtaaca gcatcttagt
    10681 ctgataacca cctgcaacca aggctttatc cagctgaatc atggcaatct tgagaatatc
    10741 tgctgccgaa ccctggatag gtgagttgat agcagttcgc tccgcaaaac cacgaatatt
    10801 gaagttgcgc gaattgatat ctggcaactc acggcgacgc ttaaagaggg tctctacata
    10861 gcccttatca cgcgcctccc gcaccacttc atccatgtag tttttaatac ctggaaaacg
    10921 ttcaaagtag gtatcaatgt aggctttggc ttccttacga ctaattccca aattattaga
    10981 caagccaaag tctgaaatcc cataaaccac tccaaagtta actgccttgg cattgcgacg
    11041 gtcatttgca gtcacattat caggacgctc aatgccaaag acccgcatgg ctgtcgaagt
    11101 atggatatct gccccctctt ggaaggcctt aatcaagtgc tcatccttag aaatatgcgc
    11161 caaaacgcgc aattcaatct gtgaatagtc agagctgagt agcacactat cctcccactc
    11221 tggcacaaaa gccttccgaa tcaagcgccc ttgttccaat cgggcaggaa tattttgcaa
    11281 gtttggatcc acactagaca aacgcccggt ctgggtcaaa tcctgcacat agcgagtatg
    11341 aatctttcca tcagccaaaa tccagtcctg caagccaatt acataagtag attgaatctt
    11401 agcaatttga cggtaatcca ggattttctt aacaatcgga gcaataggag cgagacgctc
    11461 caacacatcc actgctgtcg aataacctgt cttggttttc ttagtgtatt ctagaggaag
    11521 tcccaatttc tcaaagagaa gcacgcccaa ctgcttaggc gagttgacat taaactcctc
    11581 accagccagc tcgtaaatct cttgagtcag tttttcaatg acaagctcat tttcagcctg
    11641 catctcaagc aaggtctctt tcttgaccac aatcccagca atttccatct tggcaagaac
    11701 aaaagccaga ggttgctcca tatcataaag aagctctaat tgcccatttt cgctgagttt
    11761 ttcaagtaaa ataggctctg tttctaccaa aacagcaagt ttacaagcta agtgttccaa
    11821 gaatttctca cgttcaggaa tggccttttt aacaccctta ccgtagaaag tttcatcatc
    11881 aaccaagtaa gtctgaccat aaagactagc gatggtcgca atttcattgt cctccacagt
    11941 cgaaaggagg tatttagcca aacggatgtc aaaagcaggc gcctgcaaat ccacaccaaa
    12001 acgttgcaaa agaactttaa ccttcttaaa gtcataaact ctcagagatg ttttttctaa
    12061 gaaatccttg aaaatcgggt cttgcaacag ctcaagcttg tctgtggcat agagctgatc
    12121 cccacaagac caggcaaatc caaccaaatt atccgtatgg taattctcac caaaaagctc
    12181 aaagtggaag atagactctt cactcagcat atcttgactg atttggtcaa caatagtaaa
    12241 atccaaaccc tcagccacat cagctgacga catatttaaa gcctgcttga gctgtttgaa
    12301 gcccatctca tcgtagaatt tcccaagatt ttcaacatct ggaccactat agaccaagtc
    12361 ctctaaacca atcgcaatcg gtgccttggt atcaatggtc gctagtgttt tagacaaaaa
    12421 ggcctgttcc ttgtcattga tgagattttc cttcatctta gaagtcttca ttccatcaat
    12481 attttcataa atcccctcaa gcgaaccatg ctccagcaag agcttaatac ccgtcttttc
    12541 accgactttg gtcaccccag ggatattatc cgacttatca cccatgagcg ccttgagatc
    12601 gataaactga gctggtgtga ggcccatttc ttccatgagg taatctggcg taaaggcctc
    12661 aaactcagcc acacctttct tggaaatttc aaccaccgta tgctcatccg tcagctgaat
    12721 caaatccttg tccccactga caatggtaat atcaaaacca tcctgctctg ctagcttatc
    12781 cagcgtccca atgatgtcat ccgcctcata ctgagccagc tcatagtgac gaatccccat
    12841 atgatccagc aactcacgaa tgaaaggaaa ttgctcacga aactcatcag gagtcttggc
    12901 ccgaccaccc ttatagtccg catacatctc tgtccggaag gtcgtctttc ccgcatcaaa
    12961 agccaccaaa atatgactcg gctcaacccg ctccaacaaa tgactcaaca tcaactgaaa
    13021 accataaatc gcattggtat gcaaaccagc cgcattctta aaacggtcca actgctgata
    13081 cagcgcaaaa aacgcccgaa aagctacaga agacccatca atcaataata attttttctt
    13141 atccatacac ccattataaa ggaaagaatc aaaaaatacc attgggaaga gctagagcaa
    13201 gtatttttca aactttttcc gaataaatag atagagccag agaatttagt aaacctagat
    13261 ttaaaaatgt gctataatat agtatattga atctataata gtacaccttg actgctaaaa
    13321 tatttctata aattaatttg actttcctga tagagttatt cacatcttat ttcaactcac
    13381 tatagaagga ggaataggag gattctcaga catccgggca tcagcccaac taatgatttg
    13441 attgctaaga aaatattcag caatccagaa atcacttgtc aatttattcg cgatatgctg
    13501 gacttgccag caaaaaatgt gaccattttg gagggaagcg atattcacgt attactctcc
    13561 atgccttact cggtgcagga tttttatacc agtatagacg tcttggcgga gttggataac
    13621 ggtactcaag taattattga gattcaagtc catcatcaga attttttcat caatcacttg
    13681 tgggcttacc tgtgcagtca ggttaatcaa aatcttgaaa aaattcatca gcgagaaggt
    13741 gatactcact agatctacaa acacatcgct cctgtttacg tcattgctat cgtggatagt
    13801 aattatttct cagatgacct ggcttttcat agctttagta tgcgcgaaga cacaacaggt
    13861 gaggtattgg cgattaccaa caatggacag gaaaaccatc tggttaagat ggcattcttg
    13921 gaattaaaaa atacagagaa accagcaaag acaaggttcg caagccatgg ttggagtttt
    13981 tcggcaacaa gccctttacc cagcaaccgc aacgagccat tacccaagca aatcaactgc
    14041 tggactacaa gagctggtcc gaggaggaca ggaaaatgtt tagtcaacta catatgcgag
    14101 aagaacaagt cttgttagca caggactatg ccttggaaac tgctagggct gaagaccttg
    14161 aacaaggact agagcgtggg aaagttgaag gaagggcaga aaggaaactt tttgccttcc
    14221 tagacatagt acgccaaggt cttctgactt ctgaggttgc cagccagcaa ttaggtatgt
    14281 cagtatctga atttgaggca ctgttgtaaa atggctccat aatatccata gtgagtaaat
    14341 cccctatgga tattatggag cctattttgt gtagaaaaaa agtcccatat gacctataat
    14401 gaaaagcgac aaaacaactc attagaaaga atcatatgga acaattacat tttatcacaa
    14461 aattactaga cattaaagac cctaatgtcc agattttaaa catcatcaat aaggatacac
    14521 acaaggaaat catcgccaaa ctggactacg acgccccatc ttgccctgag tgcggaaacc
    14581 aattgaagaa atatgacttt caaaaacctt ctaaaattcc ttatcttgaa acgactggta
    14641 tacctactag aattctcctt agaaagcgtc gattcaagtg ctatcactgt tcaaaaatga
    14701 tggtcgctga aacttctgat gacgtacagt catatttctt ctctttttat tatatcacag
    14761 ttttaaatct agctttacta gattcaccgc tactatctat ttattcggaa aaaagacgaa
    14821 aaacctgaga atcatctcag gcttggtcat taaatttttt tctcaatatc gaaaagtgga
    14881 gaaagtggtc gtttttcatg aatacgtacg atagcatccc ctaggagatg agcgattgaa
    14941 atctgctcaa tcttatcaat caaacgctct tctggcagat agatggtatc caaaacaacc
    15001 aatttcttaa tagctgattt ttggatattg tccgtagcag gaccagaaag aactgggtgc
    15061 gtacagcttg catagacttc aacagcacca gcttccgcaa gagcatctgc cgcatgacaa
    15121 atcgttccag cggtatcaat catatcatca atcaagatac aagtcttgcc ttcaacctta
    15181 ccgatgatgt tcataacttc actagtattc atcttatcaa cgctacgacg tttatcaata
    15241 atagcgatag atgttttcaa aaattctgcc aacttacgag cacgagtcac ccctccatgg
    15301 tccgggctga caaccacata gtcagaacca accataccac gacgctcaaa ataatctgca
    15361 atcagaggag cacccatcaa atgatccaca ggaatatcaa agaatccttg aatttgcgca
    15421 gcatgcaagt cgatggtcaa taaacgatcc actccagcta cttcaagcat atttgcgaca
    15481 agttttgaag tgattggctc acgcgctctc gcctttctat cctgacgtgc atacccatag
    15541 taaggcatga caacattgac agattctgca ctcgcacgct tcaaagcatc taccataatc
    15601 aaaatttcaa gcagattgtc atttacaggc gaactagttg attgtaggat aaagacgtgt
    15661 ttcccacgga ttgattcttc aatgttgacc tgaatctctc catctgaaaa ttggcgaaca
    15721 cttgatttcc ccaactctat cccaatctcc tgcgccacac gttctgccaa ttctttatta
    15781 gaagaaaggg caaacagctt taaatcagaa aaagacatga tttcctccgg tatatatgta
    15841 taacttgtgc ttttcacaag attttccatc taccattgta gcgctttttg cactattttt
    15901 caatcaaaaa taaaagaagg gcaccatatt tgtacccttg catcattctt ttgaaaaata
    15961 ttctaggtca tcaactcatt gtgtttctca acaaagcaat aagcatgata aaaaccatag
    16021 agagcaatag ccgtaaccac tggaatcgct aaaggcaact ctgtttccaa ctccacaaaa
    16081 ggagagttaa acaagaagtg agttcccaag gctaaaccta gaaaaataag gccctgtttc
    16141 ttgccaacct tctgtccttt ataggctctg taaagcaagt aaacacctac tacagctaga
    16201 cctgaaaaag tccagtgaga ggcaattcct gagatgatac gctctaaaat tcgcgaaata
    16261 gtaaagtcaa agccctctgg caaatccgta cgaatataac caatatcctc aatcatttgg
    16321 aatcccaaac cggaagcaat tccaagtaaa aacaaagatt ttaattttcg cacaggaatc
    16381 aaagccaaaa caaaaacaag tggcaataat ttcaaggatt cttctaccaa aggagccaca
    16441 atagcacttt caaaggcatt taaaaatgta ctatctggga aaagaacccc cagtaaatca
    16501 tggatataag tattagcaaa actagacaac cagcctgaaa ggaacatccc tcccaataaa
    16561 gacagaatca aaaccttctt tggcaattcc cattttttcc caatacggaa gagaaaataa
    16621 agagccggaa tcatgtaaaa gagagctaga aagatagaaa ctcccattag tccatattcc
    16681 gcacctgacc tcgaaccgtc cgtatagtag atggtttcat actgtaaacc aatacatagc
    16741 aataaaataa aaataaaata ctgcttttct tcatacactt tctttctaaa tgaagtattt
    16801 ataattctac gactgtcata cttcctgtat caacattgta aatggcacca gagataatga
    16861 catcgtctgg tattagggga gactcgataa gcagttgcat atcctcgcgt acactctctt
    16921 ctatatcttg gaagggcaag aaatcctggt ctgacacatc tacacctaat tcctctttta
    16981 aatactcctg aaaaggttca ttttcaaagg tctgagcacc acagtctgta tggtgcaata
    17041 ccacaatctc tcttgtcccc atttgttgct gggaaataac tagcgaacga atcatgtctt
    17101 cagtcactcg accacctgca ttccgcaaaa tatgagcatc cccaagtgcc aaacctagag
    17161 cttgcgcaac gtgcaaacgt gagtccatac aggtcacaat ggctactctg gttttaggtt
    17221 taagtggcag atttaactgc ccatgtaggg caacataagc ctgattggct tgcataaact
    17281 gttcaaaata cgacacgatt ccctccttga aaatttgata gtcaaatatt tctcctatct
    17341 tatcattttt aagagaattt gtcacggatt atgcaaagac ctttttcaag acttcctgaa
    17401 tcgttgtcac gccaatgacc tgaatttcct taggcagagt gattcctgtc aaggaattct
    17461 gaggtacata aatcttagta aagcccagtt tagcagcttc gttgatgcgt tgctcaatac
    17521 gattcacgcg ccgaatctct cctgtcaagc ccagttctcc gacaaaacat tcctgaggat
    17581 tagttggctt gtctttgtag ctcgaagcaa tagcaactgc aacagccaag tcaatggcag
    17641 gttcatccaa tttaacacca ccagcagatt tgagataggc atcctgattt tgcaagagaa
    17701 gccctgcccg tttttccaaa acagccataa tcaagctagc acggttaaaa tcaagtcctg
    17761 tcgtagtacg cttggcattt ccaaacatgg tcggtgttac caaagcctga acctccgcca
    17821 aaatcggacg cgtcccttcc atggttacaa cgatggagga accagtcgcc ccatccaaac
    17881 gctcttctag gaaaacttga ctcggattga gtacctcaac caagccgccc gactgcatct
    17941 caaaaatccc aatctcatta gtggaaccaa aacgattttt gaccgctctc aaaatacgaa
    18001 aggtgtggtg acgctcccct tcaaagtaaa gcaccgtatc caccatatgc tccaacatac
    18061 gaggcccagc caaggttcct tctttggtca catgacctac gataaagatg gcaatgttat
    18121 tagtcttgac caactgcatg agttcagcgg tcacttcacg cacctgagaa acagacccct
    18181 gcacccctga aatctcagga gacatgatgg tctggatgga atcaataatg agaaagtctg
    18241 gctggatacg ctccacttct gcacgaacac tctgcatatt ggtctctgca tagagataaa
    18301 actcactatc aatatcacct aagcgctctg cacgtagttt aatctgctgg gcagactcct
    18361 ccccactgac atagagaact gtccccactt gggacaactg ggttgagact tgtaggagaa
    18421 gagttgattt cccaatccca ggatccccac cgatgaggac gagacttcct ggtaccactc
    18481 cgcctccaag cacacggttg aattcctcca tctccgtctt ggttcgattg acattgatgg
    18541 aagtcacctc agctagtttc atgggcttgg ttttctcacc tgtcaaggac acacgcgcat
    18601 tcttgacctc ggcaacctca acctcttcca caaaagaaga ccaagaccca cagttggggc
    18661 aacgtcccag atatttaggg gaattatacc cacaattttg acatacaaat gtcgcttttt
    18721 tctttgcgat gacaaacctc tttctatatc tctaactcac actcaatcac ttggcaaaaa
    18781 tcaatcttct catttggcac aaactggcgc atgagcattc gatgagcaac aactaccaca
    18841 gtctgatgtt ctcgatactt agacatacat tctagaaacc gagacttcat ttccgtagct
    18901 gtctcatatt gaataggact attaggaagc aactccccct tgttttctaa aaacagtctt
    18961 ctagctgttt caaagttttc tattcctgtt ttatagacct gccattcatg taataaaggc
    19021 tctactctta aaggaagacc cgtagcacag accacatacg aagccgtttc taaagctctt
    19081 gtgactgcag aagatacgat tatttcagct gacgagagta aaggattttt gctcaatttc
    19141 tggacttgct gccgtcccat ctcagacaag ggtgccaaat ctatcccaaa tcctatataa
    19201 gaacgctcct ctaactcacg gtaatctggc tccccatgac gtacaaagat aatcttcatt
    19261 ctagtgccct gtcgatccaa atccaccagt tcgaacgcca tcagctgcat ctccatctgc
    19321 aattaagaaa gtagcaaaaa cagcctggac aatacgctcc ccaacttcaa gaacaacctc
    19381 ttggtctgtg atattcttca tctgcgcaaa aatatgccct tcatttccag gatttccata
    19441 ataatcccca tcaatgaccc caactgagtt aattaaaacc aagcccttct tacgaggatt
    19501 tgaagaacga tcatagaggt agagaacctc agtcggctgc atataagcct taacccctgt
    19561 cggaaccaag acaatctctc ctggcgcaac aactgtacgc acagcaacct ttaagtcgta
    19621 accagccgca tgcgctgtct cacgcttggg caataaattt tcatctgtaa aactcgaaac
    19681 caattcaaaa ccacgaattt tcataatttt ctcttttcta ttatcattta ttctagatta
    19741 ttctatctta tttattcgga aaaagcacga aaaaagagca cacaattcaa atcgcttagg
    19801 gctgctggat tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata
    19861 tcacattcct attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc
    19921 tgcatgatag ctgcgcattc atcttccaaa attcctattt caacctccac acgatgattg
    19981 agacgctcat ctgtcaagat atcgtacaaa ctcccagcag cgccaaattt ctggttttta
    20041 gccccataga ccacatttgg aatacgggca agcccaatcg ccccactaca catgacacaa
    20101 ggttcaatgg tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc
    20161 gcatcctcta tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca
    20221 ttatgcccac gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca
    20281 tcgtgttcaa gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct
    20341 tcaagcgtat aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat
    20401 gaattccaac acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa
    20461 aagaaaagtt taggatattt gttacaacaa gttaggaggt cttcttgtaa ccgtctatag
    20521 tatacccgac ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa
    20581 tatttgtttg ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt
    20641 cactcacacg acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgaactc
    20701 cggtaatatc ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt
    20761 gttcaagact agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaga
    20821 ttttcacagt atccaaaccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac
    20881 cagaaacacg acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac
    20941 gaccagttgt tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa
    21001 acaactcagt tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta
    21061 caaccttgtc aatcttgctt ggaccgacac cagaaccaat tgtcacacca ccagctacag
    21121 ggtttgatga cgtaacaaat ggataagtac cttggtcgat atctagcata acaccttgtg
    21181 caccttcaaa aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat
    21241 ctatcacgta tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga
    21301 aaacaatcgc tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac
    21361 gttctaaacg ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac
    21421 gagcagcctt gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt
    21481 cgcccttagc ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg
    21541 cacgatcaga aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact
    21601 cttttacaag agatttagga tttacaacca taccattccc aatgacagat attttttcag
    21661 ggaagaaaat cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg
    21721 tgtgaccagc attatcacca ccttggtaac gtgcaatcac ttctgcattc gctgaaagga
    21781 agtctgtaat cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag
    21841 tcataatttt gtctgagcca tcaggctctt cctttctcac atacatggca ggactctcac
    21901 ctgcaattat atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca
    21961 atagaaagat ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt
    22021 actatcatct ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca
    22081 agaaataaaa ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata
    22141 atggtaaacg ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa
    22201 aaatttaaaa tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc
    22261 ttcaatacta tcatagaaat tagccatctg ctcataaatt ttttgtaaca taatcaaata
    22321 ctccttttct tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc
    22381 ctgaattgtt aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa
    22441 acaaatttgc tacctaaatt tcaaacaatt aaagttctaa aaagaccgcc ttaaaacttt
    22501 tgggtaaatc ctattagaac tataatattt ttatataggt attatggttc tgattttcta
    22561 gtataaaaaa attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg
    22621 ctcaaaaatg gagctcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat
    22681 catcaaccaa aagattgctc agaagctaat tgaaaagact tctatgaccg acattgatca
    22741 tcagttgtct atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca
    22801 tgatttttcg cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac
    22861 tgtttcaatc ggggatggag atgagcttta ttgctcagga ctttgataaa ctcaatatca
    22921 taactgttct tgagagcaga acacaagcca tcatccgaaa tcccatgaat acaaggctat
    22981 caagcgctac tggaagctca ttcaacaaga tagtcagaaa ctgagtgata aacgatttta
    23041 tcgccctact tttcgtatgc acttgactaa taaagaaatt ctagataaac ttttgagcta
    23101 ttccgaagac ttgaaacacc actataatct ctatcagctc ttgcttttcc acctctgttt
    23161 caaactttgt ttaaaacctt cctcaaagat aaagagaaaa tcgtcaacgc ccttcaatta
    23221 ccttattcca acgccaaact ggaagccacc aataatctca tcaaacttat caagcacaat
    23281 gcctttggtt ttaggaactt tgaaaacttc aaaaaagaaa ggacgaaatt tgtcctttct
    23341 agatcttcgc tttcttcaac ccactacagt tgacaaagaa ccgaaaaatg tctcgcctct
    23401 aatatagtca attgaaacaa gaacaagaga aaagagcctc gtaaaaggta ttgcaacttg
    23461 gtaatacctt tttgaggttc tttttgatat aagcccatgt tttctcaata ggattgtact
    23521 caggtgagta gggaggaaga ggtaaaagtt tatgcccaaa ctcctcgcat aaaagttcta
    23581 acttacccat tctatggaat cttgcattat ccataataat aaccgatggt gtggttaatg
    23641 ttggtaagag aaacttctga aaccaagctt caaaaaagtc gctcgtcacc atctcttcgt
    23701 aagtcattgg agcgattaac tcaccatttg ttagacctgc aaccaaagaa atcctctgat
    23761 atcttcttcc agatacttta cctctt
//
LOCUS       DAVLHB010000031        23014 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLHB010000031 DAVLHB010000000
VERSION     DAVLHB010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.031"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            151..804
                     /locus_tag="VXE36_001366"
     CDS             151..804
                     /locus_tag="VXE36_001366"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0779663.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            814..1278
                     /locus_tag="VXE36_001367"
     CDS             814..1278
                     /locus_tag="VXE36_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0779664.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWIPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1291..2559
                     /locus_tag="VXE36_001368"
     CDS             1291..2559
                     /locus_tag="VXE36_001368"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0779665.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2573..2833
                     /locus_tag="VXE36_001369"
     CDS             2573..2833
                     /locus_tag="VXE36_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779666.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2844..4205
                     /gene="pdrM"
                     /locus_tag="VXE36_001370"
     CDS             2844..4205
                     /gene="pdrM"
                     /locus_tag="VXE36_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0779667.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4359..5327
                     /locus_tag="VXE36_001371"
     CDS             4359..5327
                     /locus_tag="VXE36_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0779668.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5343..6335
                     /locus_tag="VXE36_001372"
     CDS             5343..6335
                     /locus_tag="VXE36_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0779669.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6553..7596
                     /locus_tag="VXE36_001373"
     CDS             6553..7596
                     /locus_tag="VXE36_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0779670.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7660..9345
                     /gene="lpdA"
                     /locus_tag="VXE36_001374"
     CDS             7660..9345
                     /gene="lpdA"
                     /locus_tag="VXE36_001374"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0779671.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9409..10398
                     /locus_tag="VXE36_001375"
     CDS             9409..10398
                     /locus_tag="VXE36_001375"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0779672.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10471..11541)
                     /gene="xerS"
                     /locus_tag="VXE36_001376"
     CDS             complement(10471..11541)
                     /gene="xerS"
                     /locus_tag="VXE36_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0779673.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGCKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12125..13675)
                     /locus_tag="VXE36_001377"
     CDS             complement(12125..13675)
                     /locus_tag="VXE36_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0779674.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13691..14470)
                     /locus_tag="VXE36_001378"
     CDS             complement(13691..14470)
                     /locus_tag="VXE36_001378"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0779675.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILSKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELLKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14457..15308)
                     /gene="ylqF"
                     /locus_tag="VXE36_001379"
     CDS             complement(14457..15308)
                     /gene="ylqF"
                     /locus_tag="VXE36_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0779676.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMTDKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15527..15703)
                     /locus_tag="VXE36_001380"
     CDS             complement(15527..15703)
                     /locus_tag="VXE36_001380"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0779677.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(15755..21540)
                     /locus_tag="VXE36_001381"
                     /pseudo
     CDS             complement(15755..21540)
                     /locus_tag="VXE36_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(21749..22927)
                     /locus_tag="VXE36_001382"
     CDS             complement(21749..22927)
                     /locus_tag="VXE36_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779678.1"
                     /translation="MTLPVRKSLHNAVLQASEADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQCLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDNQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         6539 a         4484 c         4705 g         7286 t
ORIGIN      
        1 ttataaaaaa tagccagtct ttataaactg tattcacgta ttcaaatcgt atatatagtc
       61 gatttattaa atctttagat aaactgtaaa aagtggtttc catagccact ttttgctata
      121 atagaggcag taaaaatgaa ggagtcggct atggaacact cgtcttggca tgctttgatt
      181 aaggcgcaat tacctgaggg ttatttcggg aaaatcaatc agtttatgga gcaggtctat
      241 tctcagggga ttatttatcc acccaaggaa aaggtttttc aggctctctt gacaacactg
      301 cttgaagaag ttaaggtggt aattctaggg caagacccct atcacggacc aggtcaagcg
      361 cagggcttga gtttttctgt acctgactct atcccagctc caccatcctt gcaaaatatc
      421 ttgaaagaat tgtcagatga tatcggagtt aagaaatctc atgatttgac agcttgggct
      481 gagcaaggag tcttgcttct taatgcttgt ttgactgttc ctgctggaca ggccaatggt
      541 catgctggtc aaatctggga gccttttact gatgctgtga ttcaggtggt caatcatcta
      601 gatagaccag tcgtttttgt actctgggga gcttatgcac gtaagaagaa ggcattagtt
      661 accaatcctc atcacttgat tatcgaatca gcccatccaa gtcctttgtc ggtttataga
      721 ggattttggg gttccaagcc cttttccaag gccaatgcat tcttaaaaga gacaggacaa
      781 gagccaatcg attggcttag ataaggagaa aatatgcctc agttagcgac gatttgctac
      841 attgataatg ggaaagaact gctcatgctc catcgtaata agaaacccaa tgatgtccat
      901 gaagggaaat ggattggtgt gggtggtaag ctagagagag gagagacgcc ccaggaatgc
      961 gcggcgcgtg aaatccttga agaaacaggg ctcaaagcca agccagttct aaaaggtgtc
     1021 atcacttttc ctgaatttac accagattta gactggtaca cctatgtttt taaggtgacg
     1081 gagtttgagg gcgacttgat tgactgcaat gaggggacgc tagaatggat tccctatgat
     1141 gaggttttga gcaagccgac ttgggaaggt gaccacacct ttgttgagtg gcttttagag
     1201 gataaaccct tcttttcagc caagtttgtt tatgatgggg ataaattgtt ggatacccaa
     1261 gttgatttct atgaataaag gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg
     1321 gatcccaagt ctggtttgga tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc
     1381 aaaattgcgc ctgagatcac ggaagaagga gcagaaacga ttgatgctac tggtcttgtg
     1441 gttgctcctg gtttggtcga tattcatgtg catttccgtg aacctggtca aacacataaa
     1501 gaagacattc atactggtgc cctggcagcc gctgcaggtg gttttactac tgtcgtcatg
     1561 atggctaata ccagtccaac catttcagac gtggagactt tgcaagcagt tctccagtca
     1621 gctgccaaag agaagattaa tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt
     1681 aaaaacttga ctgactttaa ggcgctctta gaagctggtg cggctggttt ctctgatgac
     1741 ggtattccgc ttgagagcag taagattgtc aaggaagcca tggaggaagc caaaaaactc
     1801 aataccttta tcagccttca tgaggaagat ccaggtttga acggtgttct tggctttaat
     1861 gaaaatattg ctagagaaca tttccatatc tgcggtgcta ctggggtggc tgagtacgct
     1921 atgatggcgc gtgatgtcat gattgcctat gcaactaaag cccatgttca catccagcat
     1981 ttgtctaagg aagaaagtgt taaagtagtg gagtttgctc aggggttagg tgcagaagtc
     2041 acagcagaag tagcgccaca gcatttctct aagacagaag cacttttttt aacacaaggt
     2101 agcaatgcta agatgaatcc accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa
     2161 ggtctcaaat caggtgtcat cacagttatt gcgactgacc acgcgcctca tcatgtagat
     2221 gaaaaaaatg ttgaggatat taccaaagcg ccatctggta tgactggctt agaaacatcc
     2281 ctgtctctcg gcttgaccta tttagtagaa gctggtgagt tgagcttgat ggaattactt
     2341 gaaaaaatga catacaaccc agccaagctt tacaactttg aagcaggtta cttggctgag
     2401 aatggtccag cagatatcac tatttttgat gccaaggctg accgccttgt ggactcccat
     2461 tttgcttcca aagcagctaa ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa
     2521 tataccatct gtaagggaca aatcgtctat caagcttgat aggagttaga atatgaatta
     2581 ttttcgaaaa cgtagggaga gacaagcgaa atctaatagt ggaatttact gtcccgcagc
     2641 taatcgttcc aaaattcaat atgaaactaa agaaaaagct gaccatgcgg ttcaatatga
     2701 taacggaggt ttagttagaa gctattattg tcgtacatgt gcgtgttggc atactacttc
     2761 aaaatctaat aaacctccgc taagtttgaa aaactatggt ctgaaactct ttggtttaga
     2821 taaatcagaa tagaaagaga agtatgtata agacaaagtg tttacgagag aagttagtat
     2881 tatttttaaa aattttcttc ccaatcctga tctaccaatt tgccaattat tctgcctctt
     2941 ttgttgatac tgcaatgaca ggtcaataca acactatgga cttggctggt gtatctatgg
     3001 caaccagtat ctggaatcct ttctttacat ttctaacagg gattgtgtca gccttggtgc
     3061 ctatcattgg tcaccatctt ggtcgaggca aaaaggaaga agttgcgtct gatttttacc
     3121 aatttattta tttggccttg ggcctatctg tggtcttgct ggggatggta cttttcttgg
     3181 caccaacaat cttgaatcat attgggttag aagcagcagt agcggcagta gcggttcgct
     3241 atctttggtt tttatctatc gggattatcc ccttgttgct ctttagcgtc attcgttcct
     3301 tgctggattc gctgggcttg accaaactgt ccatgtacct catgcttttg ttactccctc
     3361 tcaatagcgg atttaactat ctcttgattt acggtgcctt tggtgttcca gaactgggag
     3421 gggctggtgc tggtttagga acatccttgg cctactgggt cttgcttggg atttctgttc
     3481 tggttttatt taaacaggag aagctcaaag ccttacacct tgagaaacga attccactta
     3541 atatggataa aattaaggaa ggagttcgtt taggtctgcc tattggggga actgtcttcg
     3601 cggaagtggc tgtcttttca gtggttggct tgattatggc taagttttcg tccttgatta
     3661 tagctagtca ccagtcagct atgaactttt caagtcttat gtacgccttt cctatgagta
     3721 tctcatcggc tatggctatt gtcgtttcct atgaagtggg agccaagcga tttgatgatg
     3781 cgaaaaccta tattggtcta ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa
     3841 ccttccttta catttttagg ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta
     3901 tcgatttgac agtgcgtttt ttaacttata gtcttttctt ccagttagca gatacctttg
     3961 cggcgccgct tcagggaatt ttgcgggggt ataaggatac agttattcct ttttaccttg
     4021 gtttgcttgg ttattggggc gtagcaatcc ctgtggctac gctatttgat tccctaacag
     4081 attttggagc ttattcttac tggatcggct tgattattag tttgattgtg agcggggcgc
     4141 tctaccgttg gcgtttaact gtgattatga agagatttga atctttagca aaatccaaat
     4201 gctaaaaagt ttgtgaaaaa atattcttga caagaaaatc ccttgttttc acggggtttt
     4261 cttttttatt ttgtgaaatt tcttttagaa aaactttgac agtatttgcc aaaagcggta
     4321 aaatagtaag gtaagaagaa agttagaaag gcaagaagat gtcaacttta gataaaaatc
     4381 ttttgctaga aatgttccgt aagatggaag aaatccgtcg catggactta aaaattgcac
     4441 aattagtaaa gaaagggaaa gtgccaggaa tgacgcactt ttctgttggt gaagaggcag
     4501 ctaacgtggg ggctatgtta gctctcaatc cagatgatct gattacctca aaccaccgtg
     4561 gacacgggca agctattgct aaagggattg acctcaacgg aatgatggct gaaatccttg
     4621 gtaaatacac tggaacctgt aaagggaaag gtggatctat gcatatcgct gaccttgatg
     4681 ctgggaacct tggtgccaat ggtatcgtag gtggtggtat ggggatcgct gtcggtgcag
     4741 ccctcagtca gcaaatgcaa aataccggta aaatcgttgt ctgcttcttt ggagatggtg
     4801 cgaccaatga aggtgttttc cacgaagcag tgaacatggc ttctatctgg aacctgccag
     4861 tcattttcta ttgcattaac aacggttacg gtatctctgc ggatatcaag aaaatgacca
     4921 atatagaaca tatccatcaa cgtagcgccg cttatggaat tcctggaatg ttcatcgaag
     4981 acggtaacaa tgtcatcgat gtctatgaag gatttcagaa agctgtggac catgttcgca
     5041 gtggcaatgg tccagtcttg attgaaagtg taacttatcg ctggctcggt cactcatcat
     5101 ctgaccctgg taaatatcgt acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa
     5161 tcgaaaacct ccgcaattac cttattgaaa ataacattgc aagtgccgaa gaattggaag
     5221 aaatccaagc gcaagtaaag gaagcagtag aagcttctgt taaatttgca gaggaaagcc
     5281 cattcccacc gcttgaatca gcctttgaag atatttacgc agactaagga gaaagagata
     5341 aaatggaaac aaaaacaatg tccttccgtg acaccattat ccttgctatg tctgaggaaa
     5401 tgcgtcgcga tgaaaatgtg ttcttgatgg gagaagacgt cggtgtcttc ggaggagact
     5461 tcggtacttc tgttggaatg cttgaagaat ttggtccaga acgtgtccgt gactgtccga
     5521 tttctgaagc tgccatctct ggagcagcag caggagcagc catgacagga cttcgtccaa
     5581 tcgtcgatat gaccttcatg gacttctctg ttattgccat ggacaatatc gtcaaccaag
     5641 ctgctaaaac acgttacatg tttggtggta aaggtcaggt tccaatgact gttcgttgtg
     5701 cagctggtaa cggagttggc tctgccgccc agcactcaca atctctagag tcttggttta
     5761 ctcacattcc aggacttaag gttgtggcac ctggaacacc tgcggacatg aaaggcctgc
     5821 ttaagtcttc tatccgtgat aacaacccag ttattatact tgagtacaag tcagaattta
     5881 accaaaaagg ggaagtgcca gttgatccag actacacaat tccacttggg gttggtgaaa
     5941 tcaaacgcca aggaacggat gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg
     6001 ttcaagctgc tgaagaatta gcagaagaag gaatttcagt tgaaattgtt gacccacgta
     6061 cccttgttcc gcttgataag gatatcatca taaactcagt gaagaagact ggtaaggttg
     6121 ttctggtcaa cgatgcccac aaaacaagtg gctatatcgg tgaaatttca gctattattt
     6181 cagaatcaga agcatttgac tatctagatg caccaattcg ccgttgtgca ggagaagatg
     6241 tgccgatgcc ttatgcacaa aacctagaaa atgcaatgat tccaacagtt gaaagtatca
     6301 aagatgcaat ccgaaaaact tataacaaag aatagggtta cataagataa gttatgtaaa
     6361 taaaataaag ctgacgagaa actttgtatc ttttaggtgc agagctcttc gtcattaata
     6421 tcttagatta gagcacgggc taaaagatcg gaaaaaagat aaatctcctt ggcttcatcg
     6481 aagccatcgt cgatttccta tttttcagtc gcttttgacg ccctttgtat cataaataga
     6541 attggagagg tcatggctga tgacaagcta agagcgactc ctgcagctag aaagttagcg
     6601 gatgatttag ggataaacct ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac
     6661 aaagaagacg tggaaactta taaagacaca aacgtggttc gcatttcgcc acttgcaaaa
     6721 cgaattgccc tcgaacataa cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt
     6781 aaaatcatga agaaggatgt tttggccctg cttcctgaaa atatcgaaaa cgatagcatc
     6841 aaatctcctg ctcagattga aaaagtggaa gaagtccctg ataacgtaac accatatggt
     6901 aaaatcgagc gtattccaat gacaccaatg cgtaaggtta ttgcccaacg catggttgaa
     6961 tcttacttga ctgcgccaac cttcaccctc aactatgaag ttgatatgac tgaaatgttg
     7021 gctcttcgta agaaggttct tgagccaatc atggaagcaa ctgggaagaa gactactgta
     7081 acagaccttc tttcgcttgc agttgttaag actcttatga aacacccata catcaacgct
     7141 tcattgacag aagatggcaa gactattatc actcacaact atgtcaatct tgccatggca
     7201 gttgggatgg ataatggatt gatgacacct gttgtttaca atgctgagaa aatgagtctt
     7261 tcagaactgg ttgtagcctt taaggatgtt attggccgta ccttggatgg taaattggct
     7321 ccaagtgagt tacaaaattc aacattcaca atcagtaatt tgggaatgtt tggtgttcag
     7381 tcctttggtc cgattattaa ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc
     7441 gagaagccag ttgtcgtcaa tggtgaaatt gtgattcgcc caatcatgag tttaggatta
     7501 accattgacc accgtgtcgt agatggtatg gctggtgcta agtttatgaa ggacttgaaa
     7561 gagttgattg aaacgccaat ctcaatgtta atttaagagc aagagtattc atttttaaga
     7621 tatagataaa ggaaggaaga catggcctta gaagtaatta tgccaaaagc cggcgtggat
     7681 atgacagaag gacaaatcgt ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga
     7741 gaaatccttt tggaaatcat gactgataaa gtcagcatgg aattggaagc cgaagaagat
     7801 gggtacttga ttgccattct caaaggagat ggtgaaactg tccctgtaac ggaagttatc
     7861 ggttaccttg gtgaagaaag ggaaaacatc ccaacagctg gagcagcatc gccagaagct
     7921 agctctgtac ctgtagcaag tacctcaaac gatgatgata agagcgatga tgcttttgat
     7981 atcgttgtga ttggtggagg tcctgctggt tatgttgcag ccattaaagc tgcccaattc
     8041 ggcggtaagg ttgcccttgt tgagaaatct gaacttggtg gaacctgctt aaaccgtgga
     8101 tgtattccaa ccaagaccta ccttcataac gctgaaatta ttgaaaatat cggtcatgct
     8161 gcaaatcgtg gtatcgtgat tgaaaatcct aacttcactg ttgatatgga aaaactttta
     8221 gaaactaaat ctaaagttgt taatactctt gttggtggtg ttgcaggact tcttcgtagc
     8281 tacggagtta ctgttcataa aggaattggt acaatcacta aagacaagaa cgtcttggta
     8341 aatggttctg aattgcttga aaccaagaaa atcattcttg ctggtggttc aaaagtcagc
     8401 aagatcaacg tccctggtat ggaatctcca cttgtcatga ctagtgatga cattcttgaa
     8461 atgaacgaag tgccagaaag ccttgttatc atcggtggtg gagttgtcgg tatcgaactc
     8521 ggtcaggcct tcatgacatt tggttcaaaa gtgactgtta tcgaaatgat ggaccgtata
     8581 gttccagcta tggatgtgga agtttctaag aaccttcgct tgattcttga gcgtaaagga
     8641 atgaccatct tgactggtac taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt
     8701 atcaaggttg aaggaaaaga cgatatcatc gcaagcaaag ctcttctttc aattggtcgt
     8761 atgccagacc ttgaaggtat tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag
     8821 gtcaacgaat acatggaaac ttcagttcca ggcatttatg caccaggtga catcaacggt
     8881 actaagatgt tggctcacgc agctttccgc atgggtgaag tttccgctga aaatgccctt
     8941 aaaggaaatc atgcagttgc caaattgaat ttgactcctg cagccatcta cactctccct
     9001 gaagtagcag cagtaggttt gacagaagaa caagcccgtg agaaatacga tgttgccatc
     9061 ggtaagttta actttgctgc taacggtcgt gctattgcat ctgacgcagc tcaaggtttc
     9121 gtaaaagtta tcgctgataa gaaatacgga gaaatccttg gtgtacacat tattggtcct
     9181 gcagccgcag aattaataaa cgaagcatca agcatcatcg aaatggaaat cactgttgag
     9241 gaaatgctga agaccatcca cgggcaccca acttactctg aagtgatgta cgaagcgttt
     9301 gcagatgttc taggaatggc catccattca cctaagaaaa aataaaacga agatagatta
     9361 gactggaagg ttatttccag tttctatcat ataaagtaaa gggatatcat gaaatacatt
     9421 atcaatcatt caaatgacac tgcttttaat attgccttgg aagaatacgc ctttaaacac
     9481 cttttggatg aggatcaaat cttcctactt tggattaaca agccatctat cattgttggt
     9541 cgtcaccaga acactatcga agaaatcaac cgtgattatg ttcgcgaaaa tggtattgag
     9601 gtagttcgcc gtattagtgg tggtggagct gtttaccacg atttaaataa cctcaactac
     9661 acgatcatct ccaaagaaga tgaaaataag gcatttgact tcaagagctt ctcaactccg
     9721 gttatcaata ccctggctca acttggggtt aaagctgagt tcacaggtcg taatgacctt
     9781 gagattgatg gtaagaagtt ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg
     9841 caccacggtt gcttgctctt tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt
     9901 tcaaaagata aatttgaatc aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt
     9961 atcaatgaat taccaaaaaa aatcacagtc gaaaaattcc gtgatttact cttggaatac
    10021 atgaaaaaag agtacccaga gatgactgaa tacgtctttt cagaagaaga attggccgaa
    10081 atcaatcgca tcaaggatac taagtttgga acttgggact ggaactatgg taaatcacct
    10141 gaatttaacg tccgtcgtgg aatcaaattc actagtggta aggttgaagt ctttgctaac
    10201 gttactgaat caaaaatcca agacatcaag atttatggtg acttctttgg tattgaagac
    10261 gttgctgcag tagaagatgt ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag
    10321 gcgctaaaaa ccattgatat cacacgctac ttcgctggta ttagccgtga agaaatcgct
    10381 gaagcggtag ttggataaat caaaaagaag ttggccaact aaccaacttc tttttttgat
    10441 atttatttac ataatttaaa atacgtaaaa tcataaacta tccagagcat tcttttgttc
    10501 atcactaaca atatgggtat agaggtcagt gacttgtgtg ctagcatgtc ctagttggtg
    10561 actgactaaa acttgtgatt tagtcgcatc atagagccta gttgctagtg tatggcgcag
    10621 tttatggggt gttacacgca ctttaaaatc ctctgagtat ttagcaacca ttttctcaac
    10681 gctagaagca tcgatacgat taggaacacc tctgtagaga gttaaaaaaa gggctgtatc
    10741 tgttttttcc gttttatagc gttgattccg aatggccaga taattctcta aataaggttt
    10801 agcaaaagca gcgacattga ctgagtcacg tttgcaacct tttcgagtaa catcaataac
    10861 catcattttt agattgagat ctcttagatc tagattaaca gcttcagata agcgaacacc
    10921 agatgccaag agaagggcaa taatggctaa atctcgttct ttatttttgt tgaatgatga
    10981 gagagctcga tttgaaagct gttgtgggtg ctcttgatcg atataagtta gaaaaccttc
    11041 tgtttcatca cctagaaaga gtttttgctt gatattttca gctctggcag caagggtttc
    11101 tttctttttc ttggtggaaa cttttttcat tacattacga tagaaataag gttccccctg
    11161 atcgttttca acctcctcgg ttagatactt gtaaagacta gaaagtgctg ataaggttcg
    11221 attgatagtt gtctgtgaaa caccttgttt tgttgtatta gcattcagca agggacgttc
    11281 acgtagataa aggataaagg attccatgtc tttcttagac atattttcca aaactgataa
    11341 aggaatatcg gatattttat cagcgtttga aataccagac tccaaaaccc agctgaaaaa
    11401 tcggtcatat tccttaaggt attcgtacag ggttgtaaaa ctgtagggca cagccagctt
    11461 agattggtag tattccagaa cataccaggg catgagttgt tttagtttgt cgattcgttc
    11521 cagtaaaatc tcacgtttca tgtattttct ccataagtaa gtatactagt agtatagcat
    11581 agacttgtat atttttcaag aaaattatag tttttcggaa agatgttata ggagtttttc
    11641 aaagtgataa aaagacttag acctacaaac aaaacagaat aaggaaaata ataaaaatct
    11701 cacccactaa acttctgtta atactacata actgaagagc tatataagga gctatgagat
    11761 acaaaacaca ttgtataata gattgaaact agaatagtac atctggactt ctaaaacatt
    11821 gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca tttctctata
    11881 taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt gatacagtaa
    11941 actcctttct agctttatac tttatcattt ctaacttaat tatagtctta tttttaataa
    12001 agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc tcattcctga
    12061 gaatcggttt tctaaataaa tcaaactgat catttacata acataaatta tgtaaatact
    12121 catactacaa caacaaatct ttgacttttc caatttcact ttttggaata accaggtgaa
    12181 tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg ccattatgga
    12241 cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt ttcccagcaa
    12301 ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat acttcttctg
    12361 gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa tccatgataa
    12421 tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct cctaccatct
    12481 cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa tagccactca
    12541 ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga ttgacacaga
    12601 taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg aaaattcctc
    12661 ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa aagtaagcta
    12721 ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga tttccgccac
    12781 caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc aagatgggat
    12841 aataagccct atccaaatgg attttttgac caatcaagtc ataaactctt ccaacgttta
    12901 atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg acgagatata
    12961 tccaatactg atctagggtc atgggaggaa tgttatctgg catatccaat actggtgtca
    13021 aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga gttgagaccc
    13081 agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt gctgcaatag
    13141 gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag gaacgttcct
    13201 ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct ccaagttgaa
    13261 tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata cctagcacat
    13321 attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt tcggcttcga
    13381 cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg gcactgagcc
    13441 aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag tacccttgat
    13501 cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga aaggatccga
    13561 cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat agtatagtgc
    13621 tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc tccatgttat
    13681 ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt tcaaagctgg
    13741 ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta gctgtgccat
    13801 atcctgcatt agtagcgaaa tcatagccag ggaactgctg atcgtattct ttcagcaatt
    13861 catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag ttggcatctc
    13921 ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca atcaaaaggt
    13981 gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg gttgcttcat
    14041 agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc gacaaggctt
    14101 ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc ttgctgtcgt
    14161 tgagaccttt aatcttacaa tttttagata aaataacggc cgcagcgact acaggaccag
    14221 caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct tgcttataaa
    14281 gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat tcagcttgaa
    14341 tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc ttttcaagct
    14401 ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg atttctttaa
    14461 tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt gccatcacgg
    14521 acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc gagggcgcgg
    14581 gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt gaagcgttca
    14641 gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt aacctcatcc
    14701 ataggaagca actggtcttt gatagctcca gtcaatgcca acttaagtgc aacagtttca
    14761 tcctcaaact taggccagag aatccccggt gtatccaaga tttccaggtc tttattggtt
    14821 ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc aatcttttta
    14881 ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccgat aatcatggta
    14941 cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc agtcatgagc
    15001 ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt gatagctagc
    15061 gtctggattt cttgtgattc aaaatactga cgccattcct tggtcattgc tggatcagcc
    15121 aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt ggtcaacata
    15181 ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa atcaacaaat
    15241 tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa ccattgaata
    15301 gtagccattg agttttttcc tttcgtagca aggatttaga tcccctattt tattttacta
    15361 ttgtttgaac atagagagtt ttcaaacgaa tgatgtccaa acagttcttg ttttatgaca
    15421 tagaaatcta ctttatatta tatcatgcct tctttatttt gtccgatgat agccttttac
    15481 cctatctttt accctatata gaaaaaagcc atcaaatgat gacttttcag agggagcaaa
    15541 aaactgttcc cgtcatatta tgaaccaaaa gaactaaact accaacagct aataggccta
    15601 aagctgtaag ctcagaagtt gatgaacctg ttgcaggaag agtttcctgc tgataaataa
    15661 gagcataact tacttcatta tcagtaggaa ttcctgcttg aatcttggtt tgttcttcat
    15721 caccttttta aactttattt cctaatagta gacactattt tttattctca aaaattgaac
    15781 ttctaaaatc atttgtttgg tcaagatagg ctttaaagat tgctctcttg agcttgtgga
    15841 cttcactatc tatgtctgga ttgtagttat tccaatggta gtaattgtgt tctgcatcct
    15901 tacgaacagc aacgtccatt aatttctgta attcatctac actgcttgta gttttcttgg
    15961 caaatgtttg ccaaggctgt gttgtatcat taaaagtaac tttgttcaat ctatcaaact
    16021 gatcttgtcg ttcttgatac atagctttct taaactcact ccaagtatga tattggttat
    16081 taaatacctt ttccaaaacc aagtcatctg taaccaaacc tcttgtttta ccgtagagat
    16141 tgattgtctt gcccttttgt ttggcttctt cttcgtattg gtttgagata tatggtacca
    16201 taccatcttt aaagccttta gcagctagta gttcataggc tatacgacgt cccatcaggt
    16261 cacctggtgt tcctatatca ttacttaatg cagcataaat cggtgcaaat aacttaatag
    16321 tgaagtagcc atttctttcg tatttacctg aggcatattc cctagacgaa agaatattat
    16381 tatcaatcaa atcattgaat gaacgtagtc tttcaacttc ttctactgtt agatttctga
    16441 caacatttgt tgcatagacc ttatttccat caggatcagg atggtactca tttgtaactt
    16501 ttctaagaag ttgttgtttt tgattcgtat ccaatttaag aattgaattt ccttcgagat
    16561 attccaacat ataaacaacg tcaaacatgt tgtggacata ttgcttcaaa tcatctgcat
    16621 tattaaatct tgtagttgga tcaagtactt gtaatcgtcg actttctgta ctatcagatt
    16681 ttgaatgttt caagatggag ttgatggtaa tggtcgcatc atctggatgg tctggtgctt
    16741 gtaataatcc tttagcaaag aactctggtc ccaagccact tcttcgacca tatcctccaa
    16801 gataaatgtc ctgatctgag tcatgtgtca tctcatgcgt ataagtaata gctccatcct
    16861 tatccaacat tcgataaccc atataataaa ctgcatcacc tgtagcataa gcaccgtgtt
    16921 gattatgccc aactttattt ccaacaggtc caaagaaatg ttgcattgca ggatttggat
    16981 tatcaaaatc tgccacttct gtagctttcc ctacggtatt atcatcgcca aatttataag
    17041 catcgtaaag caaaatattt ctataaagtt tttcacgtgc attgtcgtct aaaatacgat
    17101 accaataatc gtagtgatct cgctgacgtt tggctgtttc acgcgcattt tcttcaacaa
    17161 aatcattgag agccttgccc gctttatggt cactactgcg gtagcgatca taagctccaa
    17221 atcctagact agacatggtc gagatgacaa atacggatct ctctggcaag gtcaggagag
    17281 gcaagaccat attgcggtat ttccatgtgg cactcgtgat acgatcataa acaccgatag
    17341 aatacttggt gctagctaac ccttgcttcg ttttcacctc ttcgatagtg gatttttctt
    17401 cgacaatgta agccttagtc tctgatttaa accagtcatt attgcttgta tttggtaaaa
    17461 agacttttcg gtaatgttcc agcgtgctaa acaaatctgt cgttccatgt tgactggcaa
    17521 gactgatacc ataagtatcg acattattct tagctagaag attgttaaag ccagatttac
    17581 ccaactcaat cagagtatct aatggtgaag cattcccctt accaaagaag tccaaatggt
    17641 acagaactag gtctttgaca ttcacctgac catagctaaa gttataccac cgttccagat
    17701 aggtcaagcc aagtagcaag gcttccttgt tgcgtttgat tttatctaca agataacctt
    17761 cagtgactgg gttagcacta gccagtccag catccgctga caagagtttt ttcaaactgt
    17821 cttccagttg ttgttttgtt ttggcgaact ggtcttctag atagagctca gtttgcttga
    17881 cgtttggaga aatacccagc gtctttctga tggcttctga atgatagtca accttttgta
    17941 agtcaagtaa gacttgcttg atgatagagg tttggtcata caggaattgg tttggcgtat
    18001 agagaagtcc agtattgccc agactatatt ctgctaattt ggcgaaatca ttctggtatt
    18061 tgagatccag cttctcagat aaatcatcct tgtagtgaag caagagtttg tttgcagtct
    18121 gtttgttaga aacaatgtct gtgatgactt ggttgtcctt catcacgact gctgacaaga
    18181 gttctttttg gtataaaaga ctgttctcat tgaccagatt tccgtatttg acgatggttg
    18241 ccttgttgta gaaaggtagc aatttttcaa tgtttttata agtcaagttg cgcttagctt
    18301 gataataggc caccttagaa aaatcactgt cttttttgcc acttgttgaa agtggctcca
    18361 ctgttggtag aatgagagga ttgatttctg cttttttgct tgcaatttga gaagcatcta
    18421 gcattgttcc tctttcttca aaggattcct tgctgacgac ctcatccttg accaaggtga
    18481 cattgtagac tctgttgtcc ttgctgctga atgtgtcctt taccttcatt tcgttatagt
    18541 ggtaaccagt gatggcattt ccgttggtta cattaacatc gctgagaaca ttggtcaaac
    18601 ttccagcatg cctaacatca ccagaagttc gatcccacaa attgcctgcc actccagcga
    18661 ctctaccaaa gtgcttgaca ttgttgatat caccttcagc atagctatct tggatctgtg
    18721 catctcggtc tactaggcct gcaagtccac ccacagtctg atctgaagta tttgtgttag
    18781 atgaaatggc cactgtcgct tttgacttag taagtaaagc cttgtcacct gtcaaatgac
    18841 cgaccatacc accgatattg taggcagcag tcgtttcata ggtattgaca attcttccct
    18901 tgaaactact ctctgtgatg cttgattgat ctgccttagc caacaaacca ccgataccac
    18961 gttcaccggc aagtacacca tccacatgaa cttgcttaat ttttgtgtta ttctgagctt
    19021 catttgccag tgaaccgata tcatctttcc ctgaaataga gacatttttc agactcaact
    19081 tttctattgt ggcccctctc aagctttcaa aaagaggctt tttcaagttg taaatagcat
    19141 aatgcttacc atctttttca ccaatcaact gaccagtaaa ggttcccttg atataggatt
    19201 tatcatcagt actaagctcc acttcgttag cattcaggct agctcctaaa tgataggttc
    19261 cagagagatt ttggtttata gctttgacca gattactaaa ggaagtaaag tttgttgttt
    19321 cttctgttcc cttcttagct agatagaagg taaaattatc tttatatctg ctttctatct
    19381 cctgctgaag cttctctact tttgctgtga ttttataaag gattttatca ttttttcttt
    19441 cctctgatat tgatgctact ggtaggtata catctttgaa tgaagaagat ttcactttaa
    19501 caaagtagct atttggattg cttggaactt gctctaacga aatgtgttgt ttataagtac
    19561 catttgacaa actgtataac tctaggtcgg aaacatttct taattcaagt gttttctctg
    19621 gttcttctac ctttttatca gggtctagtt cattttcttg tttaatttct tcgtttccat
    19681 ttgaattgga tgtgtttgat tcggttgaaa catcctcagt tgaatttccg tttgatggtt
    19741 ctggttctgt ttgtccattc tctgatgttg tattacctga attttctggt tttgttgcag
    19801 ttccgttttt ttctggttta tttgattctc caactgaggt tgtcgaatca ctaggattac
    19861 tggacacttc cccagtattt tcgctagatg tatctggtga tactttctct gaattcgttg
    19921 ttgattcttc tgcaggttga actggatttt ctgtttcttg aattgaggtt ccttctgtag
    19981 taccttcatt tggatttact ggtgtttctt ctgttggttt tactggaact tcttcagttt
    20041 tttctggacc ttgttctttg gtcttctcaa ccggagtttc aggttttact tgctcaatat
    20101 tacccttata ttttggcaat gggctacctg ctctggttca cctttatcac ttaccacagt
    20161 atctggcgac tctggttgaa cctcagtctc acctttgtcg gtcacaactg cttcgggtaa
    20221 tgtcggttga acttctggtt cgcctttatc acttactaca gcttcgggca actcaggctg
    20281 aattgcgggt tcaacaatag ctccagactg tacgtcctta tgttctacac cagtctcagg
    20341 ttgttccttt ataacttgag tttttttagt acctttttcg actattcttg gactaggcgc
    20401 agtcgttgaa gttgaaacaa tttctcgcga aacttcttcc ttgtttacag agaatattct
    20461 gacgatttca actttcttac ctaatttacc ttcttgtttt actcttacag ttccttcagc
    20521 taaatcagga ttttcttgaa tttcttcttg aaaatctatt tttgtctcta tagtttcctc
    20581 atgatataag agttcaggtt tgttcaattg acctgataaa acttcatcct gtggatttaa
    20641 tgtatttacc ccagtctttt cttttggaga aatcttctcc tctttcttcg tttctagatt
    20701 cttatgttcg gctaattgtt cttgagaatc tgaagattgt ttctcttctt ttcttggatt
    20761 gattaattca gtagagaaag gtttttcaac tacttgaact tctgtcggct tagttgaaga
    20821 aacaggtgtt tgttcctgaa tagcttgtac tgttgatgga tggtctacaa aatttggtgt
    20881 aacattataa tccacctttt gttgttttgt aggagtggct gctgattttt cttgattact
    20941 tacttcaaaa tcagaagtcg tttttccctc tttgatatat ccaatataag tgtaacctga
    21001 aatctcttta ggaagaggta atttttctcc agaggtcaat tcatagtccg tattgtaatt
    21061 tagcaaaaga tgattttcta aagcatggac tgaaactaag acaccatttc ccattcccgc
    21121 aaccaatact aaatgtaata ccgttttatt cttaaccttt ttcttggaaa cagcaaaaat
    21181 taaaattccc agagcagcta agctagcacc agcaactagg gcttgcctct cattcttgct
    21241 tccagtattt ggtaattccg ccagttgatt ttgagaattt aacttataaa caagataata
    21301 agtttcatca tcattctcca cgtatgtcgg aatatcatag acaagctgct tcttttcttc
    21361 tgatgatagc tctgaatctg ccacatattt atagtgaact cccgcagttt cttgagcatc
    21421 cacagatgaa ctagctaata cagacataaa aaataaactt gaaatcgttg cagatacaag
    21481 tcctactgat aattttctaa atgaaaaacg ctcttgtttt tcaccaaaat acttttccat
    21541 tattcctcct tgaaataaaa tttatatatg ttacaaagac ctttattata ttagtgtatt
    21601 atctattatc tatagaaaag gcagtatacc ttaattatac tcttaattta caaaaaagtc
    21661 ttaaaattga gatgcgcttt catactttgt tttatattat ttgggggtac aataacacct
    21721 accatgaaat ttacacggta ggtgttactc atatcactaa tcgttctaaa aatggtttga
    21781 ggcagttgag gagaattcct tctatccagc ttccttgtgc tgatgagcga tggtcttcct
    21841 gcaggctttt ttttagaaaa tctcggactt gttctggtgc gatttcaaat tcaaaggctt
    21901 tcattttata gaaaaagtcg atgagatgat ctgacaggta ttcagttgaa aagggtactt
    21961 caccactttt tcgatattct aataagagtc tagaaaatcg agctttttct tcaggaagct
    22021 cacgaaaata ggaattgagg atccaagtct gcttctgttt tctttcaatt ggatcctgac
    22081 tggcaattcg ttggtctttt tccagctctt tttggtattg tttggccttg atagctcgtt
    22141 ctgctctatt tttaccaaaa agaatttttt cccacttgcg ttcttcttga gtcagggtct
    22201 ctgtaaagcc aaagtaatct tgataagcac gctctgcggg tcccatggct agaaccagat
    22261 tgtctgcata ttgcttggcg attttatccc tcttcttgcg ttctttctct gcctggatac
    22321 ggagttcttg ttcgtagtca attttctcct tgcctagctt gacaaggtag agttggttat
    22381 ccgatttccc aagtaaaaag ggtttgatac acttttcaag gacttcttcc atccgagcct
    22441 ttttctttgg ttccgccttg gtccaacttc ctccctgaaa gacttctagg aaaagctggt
    22501 agtctctctc aggcgcaaat tgattgccac gattgggttt gaaaacacct ttttcccaga
    22561 gccattttag aagtcgctcg tcaaagtcac ttttattgac cttgattttt tcctttttct
    22621 gagcttttct ggttagattt tcaacctttc tgagcagttt ttcttcctct tccaattgct
    22681 ggtcaaggga caatcgatga aaatgacgaa cacagtcgct accaattgga aagaggcatt
    22741 ggcctgtgac accgttaaag agttcataag cgtatttgat ggcatttcca cagacacaat
    22801 tgctacggcc gataccgtta aaaatcaagg aaacttcatt ccattccttg gtagcttgtt
    22861 cccaagtatc cgcttctgaa gcctgtaaaa ccgcattgtg tagggatttt ctaactggaa
    22921 gtgtcatgag gtctcctttc taatactcaa taaaaatcaa agagcaaact agaaagctag
    22981 ccgcagtcag ctcaaaacac tgttttgagg ttgt
//
LOCUS       DAVLHB010000032        22032 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLHB010000032 DAVLHB010000000
VERSION     DAVLHB010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.032"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            106..270
                     /locus_tag="VXE36_001383"
     CDS             106..270
                     /locus_tag="VXE36_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0779679.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            354..920
                     /gene="amaP"
                     /locus_tag="VXE36_001384"
     CDS             354..920
                     /gene="amaP"
                     /locus_tag="VXE36_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0779680.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            932..1102
                     /locus_tag="VXE36_001385"
     CDS             932..1102
                     /locus_tag="VXE36_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0779681.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1141..1749
                     /locus_tag="VXE36_001386"
     CDS             1141..1749
                     /locus_tag="VXE36_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0779682.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1780..1983
                     /locus_tag="VXE36_001387"
     CDS             1780..1983
                     /locus_tag="VXE36_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0779683.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2093..2365)
                     /locus_tag="VXE36_001388"
                     /pseudo
     CDS             complement(2093..2365)
                     /locus_tag="VXE36_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2568..2855
                     /locus_tag="VXE36_001389"
     CDS             2568..2855
                     /locus_tag="VXE36_001389"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0779684.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3116..3886)
                     /locus_tag="VXE36_001390"
     CDS             complement(3116..3886)
                     /locus_tag="VXE36_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0779685.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMEMTLYNLFHIL"
     gene            complement(3901..4749)
                     /locus_tag="VXE36_001391"
     CDS             complement(3901..4749)
                     /locus_tag="VXE36_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0779686.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4746..6221)
                     /locus_tag="VXE36_001392"
     CDS             complement(4746..6221)
                     /locus_tag="VXE36_001392"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0779687.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLERQIPSIYALRGKLKEDDQRRMVAAYLGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6544..7899)
                     /locus_tag="VXE36_001393"
     CDS             complement(6544..7899)
                     /locus_tag="VXE36_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0779688.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7909..8226)
                     /locus_tag="VXE36_001394"
     CDS             complement(7909..8226)
                     /locus_tag="VXE36_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0779689.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8243..8560)
                     /locus_tag="VXE36_001395"
     CDS             complement(8243..8560)
                     /locus_tag="VXE36_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0779690.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8575..9471)
                     /locus_tag="VXE36_001396"
     CDS             complement(8575..9471)
                     /locus_tag="VXE36_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0779691.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9474..10736)
                     /locus_tag="VXE36_001397"
     CDS             complement(9474..10736)
                     /locus_tag="VXE36_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0779692.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGIILTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11016..12194
                     /locus_tag="VXE36_001398"
     CDS             11016..12194
                     /locus_tag="VXE36_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0779693.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12422..12868)
                     /locus_tag="VXE36_001399"
     CDS             complement(12422..12868)
                     /locus_tag="VXE36_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779694.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIYSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSILKLE"
     gene            12938..13597
                     /locus_tag="VXE36_001400"
     CDS             12938..13597
                     /locus_tag="VXE36_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0779695.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(13569..14345)
                     /locus_tag="VXE36_001401"
     CDS             complement(13569..14345)
                     /locus_tag="VXE36_001401"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0779696.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(14338..15561)
                     /gene="trpB"
                     /locus_tag="VXE36_001402"
     CDS             complement(14338..15561)
                     /gene="trpB"
                     /locus_tag="VXE36_001402"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0779697.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(15539..16138)
                     /locus_tag="VXE36_001403"
     CDS             complement(15539..16138)
                     /locus_tag="VXE36_001403"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0779698.1"
                     /translation="MTKVKICGLSTKEAAETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPVDVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(16125..16892)
                     /gene="trpC"
                     /locus_tag="VXE36_001404"
     CDS             complement(16125..16892)
                     /gene="trpC"
                     /locus_tag="VXE36_001404"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0779699.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(16889..17893)
                     /gene="trpD"
                     /locus_tag="VXE36_001405"
     CDS             complement(16889..17893)
                     /gene="trpD"
                     /locus_tag="VXE36_001405"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0779700.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(17904..18470)
                     /locus_tag="VXE36_001406"
     CDS             complement(17904..18470)
                     /locus_tag="VXE36_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0779701.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(18467..19828)
                     /gene="trpE"
                     /locus_tag="VXE36_001407"
     CDS             complement(18467..19828)
                     /gene="trpE"
                     /locus_tag="VXE36_001407"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0779702.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETACFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFLGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSSLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATSDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(20330..20407)
                     /locus_tag="VXE36_001408"
                     /pseudo
     CDS             complement(20330..20407)
                     /locus_tag="VXE36_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21014..22015)
                     /locus_tag="VXE36_001409"
     CDS             complement(21014..22015)
                     /locus_tag="VXE36_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0779703.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         6894 a         4768 c         3704 g         6666 t
ORIGIN      
        1 tttttgatat taaaataaaa aaggagggta ggcagtgttg tgatcaatta ttgctggagg
       61 tcttattggt ctcttggcag gtaaaatcac taaaaaagta gttctatggg aatcatcgca
      121 aatgtattcg ctggtttagt cggggcatat gcaggacaat ctcttttagg tagttggggt
      181 ccatcaatcg ctggaatggc tttgctccca tctattgtag gtgcagcgat tgtgattact
      241 gtagtgtcat tctttacagg tagaaagtaa acttttcgcc agtaaagtta gcaaactatt
      301 tttaaatcaa tgacgggaaa aatagtttaa atgttaaatc gaaaggattg tatatgtcaa
      361 aagcaaagaa aatatgtttc attattttct gtattttaat cttgacaatt ttccttcctg
      421 ttttgataga ttatcatcaa gttagtgatc taggtattca tctacttagc tggagacaga
      481 actccgtagt tgaattctat cttgctagat atgtcttttg ggggacagtg gttctatcaa
      541 ctttagtttt attatccatt ttagttgtga tgttttatcc taaacgttac ttggaaatcc
      601 aacttgaaac taaaaacgat acattaaaat taaagaattc ggcaatcgaa ggttttgtta
      661 gaagtttggt gagtgatcat agattgatca agaacccaac tgttcatgta aatttacgaa
      721 aaaataaatg tttcgttcat gtagaaggta aaattcttcc ttcagacaac atcgctgaca
      781 gatgccaaat aattcaaaat gaaataacta atggattgaa gcagtttttt ggtattgagc
      841 gtcaagtaaa acttgaagtt gcagtaaaaa attaccaacc aaaacctcaa aacaaaaaga
      901 ctgttagtcg tgtgaagtaa ggaagtaaaa aatggaatgg cttaaacaat atcgatatcc
      961 aattatcgct ggtctcatag gcgtatttct ggcttgtttg attgtctcct ttggcttctt
     1021 caaaacaata tttgtattga ttttaggagc actgggagtt gcagctggat tatatatcga
     1081 aaaaaactat atagataaat aaaaaaataa aaattactaa tttaattaaa ggagtttcat
     1141 atgtcaaacg aaaaaaacac aaacactaac gtagaaaaga aagatgctac tgttgtagct
     1201 cacgaaatca aaggggaact tacttacgaa gataaagtta tccaaaaaat cattggtctt
     1261 tcactagaaa acgtttcagg tcttttggga atcgatggtg gtttcttctc aaatcttaaa
     1321 gaaaaaatcg ttaacagcga tgacgtaaca agtggtgtta acgtagaagt tggtaaaaca
     1381 caagttgcag ttgacttaaa cgttattgtt gagtaccaaa aaaatgttcc agctttatat
     1441 tcagaaatca gagaaatcgt atcttcagaa gttgctaaaa tgactgactt ggaaattgtt
     1501 gaaatcaacg taaacgttgt cgacatcaaa actaaagaac agcatgaagc agactcagta
     1561 agccttcaag atcgcgtatc tgacgttgct gaatcaacag gagaattcac ttcagaacaa
     1621 ttcgaaaaag ctaaatctgg tcttggatct ggtttctcaa ctgttcaaga aaaagttagc
     1681 gaaggtgtag aagctgttaa aggtgcagca aatggtgtag tatctcacga aaacactcgt
     1741 gtaaactaag ataaaataaa tataacagga gaaattatca tgtcagtaga agaaaaatta
     1801 aatcaagcta aaggttctat taaagaaggt gttgggaaag ccatcggtga tgaaaaaatg
     1861 gaaaaagaag gagcagctga aaaagttgtt tctaaagtaa aagaagttgc cgaagacgct
     1921 aaagacgctg tagaaggtgc tgtagaaggt gttaaaaaca tgttgagtgg cgacgataaa
     1981 taaggttaaa agttacttta tctttttagt aacattagtc aaaagagtct gagtcaagat
     2041 gattctcaga aaacaaaaag ctagagattc ccaattgcgg aactctagct ttttaatttt
     2101 gcctctttct cttattatat ttcagcaggt tgttggccat gagtacgaat cccatgtcaa
     2161 ttctcacttg acgcttacct ctcagatgac atctcttata acccaaacaa acctttatct
     2221 gcccaaagac agatttcata tcaatcttac gtttagcgaa aatttgtcta cccttggaag
     2281 ataaaagtgc ctgatattct ttagttttta aacactggta acgttcattc atatacagtc
     2341 ccttttgagg ggctgattca ggttcataat cgcagtcaac attgatttca aggctgtttg
     2401 ctttctatct cccctttttc atgatatatt ttcgtacggt gcttcaatag tttctataat
     2461 aaaatgaacc aaaaatagta cacgttgcgg tataatgttc ttgtggcata ttcattagat
     2521 tttcgtaaaa agttctctcc tatttgtgag cgaacaggta tagtcaattg attgtcagtt
     2581 tgaagaccaa gagtcgtaag gcaaaggata tggcagaatc catccaaggg tggctggcac
     2641 aatttctagt gaacctcttt aaatctatta cgtttgactg tggaaaagag ttttcaaaat
     2701 ggaaagatat ttccaatcat cacgatagtg agagcttttt tgcgaatcta ggatgttcaa
     2761 gacagcggtg tctcaacgaa cattcaaata gacttttaag gtgtcatgac ttgccaaagc
     2821 agacagattt caacgaagtc agtcaagaat tttaggctgg acaaaaactc aatttcagga
     2881 gaaaatgaaa taaatattcc cacaataaaa cgcatagtat caaagttttt ccaacacctg
     2941 atattatgca ttttttaatt ttaaagactt tttcccagcc tcaagaaatc acatcccacc
     3001 taaatcctta tcaggtattt tctgagttgg taagactgtc tagcttaatt tgacaaatgg
     3061 agggcgttaa atccagtttt tacaggaagt ctatttaaat attttcacac tgaccttaca
     3121 aaatatgaaa taaattatat aaagtcattt ccatgacaaa gaataacatc cctttaaaac
     3181 agtatcttac ccaattttca ggtaagactt ttgatacaac cgtccccaat acccctccgc
     3241 atatagaagc aagaaaaata actggaacag gtgctaaatg atactgattt aaacctgtaa
     3301 ccacaacaat tgtagccaaa tgagacaact gggaaaagaa aataattgca agagaataca
     3361 tcgttgcttc ttttatcgaa atagaaaaaa acaccatcaa taaagataca ttgagcggac
     3421 caccaccaat ccctaaaaaa ctagaaatca agcccaatag aagaccacaa atcatataga
     3481 atcctatctt atcaaattga taagtttttt taaaatctgt taaaacaaat gatacaagta
     3541 gcatcacaaa tagtaaaatc atttgaacaa tggatactag ccgtactgat aattgagata
     3601 acaaaacttg aaaaataaga tgacctagaa accctcctaa aacagaagaa aaggataccg
     3661 taaaaatcaa tctccatttt atctctttac tttgtgaaaa tcttttgatt gttgaaataa
     3721 tcgccattat aaaaacagag aaactagaat aaaaagcaat atcactgacc gaatggtatc
     3781 caaaactatc cataagtggc ttaattataa ttccaccacc catgcctgat atagaaccca
     3841 atccactagc tattataatg attagaaaat aaataatctc aaccactttt taagtccatc
     3901 ctattctttc aaacatctaa aacctagatg gctactagtg gaagtagaaa tacatccatt
     3961 tctagcagct actcggtatc gattacaata agaacaatga cataaaaagg aacctcctct
     4021 gatagcatac tcttcatctt gtatcccata ttttggtaac tcatagtcat cttcattaaa
     4081 actagctaat aaggtatatc tcggattgcg acaccattcc caaacattcc caatcatttg
     4141 atatagacca aaatcattag gtaaaaattc atagacagga gccgttccta taaatccatc
     4201 taaggcagta ttttcataag gaaatcttcc ttgccaagta ttggcatgat aatatccacc
     4261 ttctaaaaga gtatctcccc aaggatattc agattgtctt cctcctctag cagcatattc
     4321 ccactgtgct tcagtcggta aagacattcc gctccaatta cagaaagcca atgcatcttc
     4381 taaagcaaca tgaactactg gatggtcttc taaacccact agattactat tctcaccgta
     4441 gggatgtttc cagcaagcgt tcggaacttg taaccaccac ggagccccag caggatgagg
     4501 atatccctcc ctttctgcct ctggaacgaa caatataaaa acaaaagacc actcttgtcg
     4561 ctcagctagt gttttatagc ctgtttcttt cacaaattga gcaaattctt gattcgtaac
     4621 tggagtatcc gcaatggaaa aatcctttac actaacagcg acttgaggac cttcaaaatc
     4681 atctaaaaag ccctcttcag aatttgttcc catcataaat gtcccaccct tgattttttt
     4741 cattttcatg attgactatc ccccgttttc gttagagttg gcgttatttt agaaagttca
     4801 acaggaacta actcttcatc cacaacaaaa ccttcttctc tatatctaag aaagtctact
     4861 aattttttct tcatctgacg aacaataggt tgatattttt cacttggata caaatcattc
     4921 atttcatgcg gatctttttt catatcaaat aactgataat gatttaaaac aggaaaccag
     4981 ataaatttcc actggtctgt caagatatat tgactagaat cttttcctaa agcatgttca
     5041 ccatgaaatt ctgttcgcca cccctcgtac tgtccaaata ataaattctt aacactccgt
     5101 ccatctagtt catctgtagt agttcctcct gccaaatcca cgagtgaagg aaaaatatct
     5161 tgaattttca ctaattgctt gattgttccc ctattaccag ctatcaatcc agccggatcg
     5221 taaatgaacg aaggaatgtg gatacttccc tgataaggat atccctttct aaacagataa
     5281 tgttcaccaa gctgatctcc atgatccgaa acaaaccaga taatcgtatc tttatcatga
     5341 cgaaattctt ttagggcagt caaaaagcga ctaatttgat ggtctatatg agtaatcaat
     5401 cccaaataag cagcaaccat tcttctttga tcatcttcct ttaatttccc tcttaaagca
     5461 taaatagacg gaatttgcct ttctaatact tcccaattcc cgatatgcaa atcgagaaat
     5521 tgaggcaagc gttccatata catatcaaaa tagtattttg ggggatttaa tggagcatgt
     5581 ggtttttcaa aagacatttt gagaaaaaaa ggaaccgttg gatctcttct ttgtaaaaat
     5641 gaaatggact cactcacaac ccagtttgtt ggatgtaact tctcatcttt atcccaaggt
     5701 ctagcttccc aagaattaca atccattccg tcatcaatca aatcaacatc ataaccaact
     5761 ttacccttta aaaaggctag atagtcacta gcataatcaa attgacttcc ataagcctta
     5821 tcatactttc tatcaacatg tagataccca tcgtgaagta agacatgatc aaacccaagt
     5881 ctctgtctgg aaggaaaaac atgcatctta ccaatacact ctgtttgata acccatatct
     5941 ttaaagactt ttggaagagt attagtaaaa ttccaaggca cctcatcttg ataaccaaca
     6001 cgtccacttt tatcttggtc taaaccagtc aataaagctg ccctagcagg aacacaagaa
     6061 ggaactggag aataggcatt ttcaaaatta taacctacac tagccatcat atctaatgtt
     6121 ggagtgctaa ctagcttatc cttactattc aaggataagg cgtctgctct catttgatct
     6181 acaacaatca aaataatatt tggctgtttt gtctgaacca taaaatctcc tttctaatat
     6241 ggcaaaagag gcacaagaag atatctacct ttactgcacc cctttctata tcaatctctc
     6301 tatataaaac aataacattc ttgttatgtt ttatataaaa atgaactaaa atatgactaa
     6361 atcgattagg aaattcaaat cattttctag tactgtttta gaagttacag tgtactattc
     6421 caacttcaat aaactataaa cctttgtcta ttaacaattt tagtggagat aagaaatcct
     6481 acacctaact catcttacac gtaatctatt tctattttat cacaaaaaac gcaagtaaga
     6541 ccattaactc aattcagttt tatctgccat tttcacaaat gggaaataag tcaagacact
     6601 aataatcaaa caaacaactg ataagatgat ggcacgccaa tcaaatgctg tagagaagaa
     6661 accatataaa attggaggca ttacccaagt aacattttgt gtaacaggtg aaacaagacc
     6721 ccagcttgtt gcccagtaag ctaccgttgc catgaaaacc gggctaagta caaatggtat
     6781 aaatagcaaa ggattcaaga caactggtaa accataattg accggctcac caatattaaa
     6841 cagaactggt gctagaccaa gtttagcaac ttttcgataa tgactgtttc ttgaaaaaat
     6901 taaaatagca agtactaatc ctaatcctcc aaaccagaca aacgccccaa aagacccact
     6961 tgtccatata taaggaatcg gttcaccttt ttggaaagca tccagattcg ctaacatagc
     7021 aactccaaat agcccttcca tgatgggagc caatacattt cctccatgga gaccaaaaaa
     7081 ccagaataac ttattcaaaa agatcatcag aataactgca aagaaacttt gagacaaacc
     7141 tagtaatggc gtttgtaaca ccttgtaaac ccaatcaatc aataagtcat tgctaagtaa
     7201 atggaaaaca taagtcaaga tagctactat atacatcgcc ataaatcctg gaatgataga
     7261 agtgaacggc ttagcaatcg cagggggaac tgaatctggt aacttgatta cccagttctt
     7321 tttcattact ttacagaaaa taatagaggc taaaaatcca atcatcatgg ctgtaaagta
     7381 gcctctggca ttaatatggt ttcctggaat cacattccca atagttacca tcagattttt
     7441 accatcaaat gctagattat caattccttg taagatttga tctaatttca catctcctac
     7501 atttgccaaa gggaaactct ttgtaactgt acttccaatc gaaatgacaa acgaagcaag
     7561 cgataccaaa ccagcagaaa ctgtatcaac cttataaatc ttagcgatat tcactcccaa
     7621 gcaatagatg aacaataagg aaacaattgg tatacttccc ttgaatacca aattattgat
     7681 gtcaacaagc cactgaaagg ttttcgtaat actttctagg tgaaattgtt gtggtaaatc
     7741 cactagaaaa gcatttaata acaaagcaat ggaacctgtc ataataacag gcatagtccc
     7801 cacaaatgaa tcacgtaaag caactaaaaa cttctgattc ccaactttca ttgcaattgg
     7861 agaaagtttt tcttgcattt tatccaacat tgtattcata gcaaattcct aatttttttc
     7921 aaatcgttcg tatacttcta ccacttcttt cgccaagtca acaaaggtca gactcgtcat
     7981 taaatgatct tgcgcgtgta ccatcaagag gctaattgat gtttcttccc cctgtgcctc
     8041 ttttgtcaac atttctgttt gagccttatg cgcctgtaat aaggcagcat tcgcatcagc
     8101 taatcttcga ttggctttag agaaatcccc tttttttgct gcctgaatag cctccatagc
     8161 attacttttg gcttccccac catacataat tagccccatt gcagattcta aattactttc
     8221 attcatagca ttctcctcaa tcttagtcta ataaactttc agctaaatct aagactttag
     8281 aaccattcat cattccataa tctgtcatcg gaataaccgc cacaggaatc tgtctatctt
     8341 ttagtttttc ttgaaagtcc cctagtaaat agcgaacttg agggcctaaa agcaacacat
     8401 ttacttcttt tgttgctaca atttcttctg cttcaggagc tggaactgca aaaatttctg
     8461 catccaaccc cttatcttct gctgcctttt gcatctttgt cactagcaga cttgtactca
     8521 tacctgctgc acatgctaac ataattgtta ctttagccat agcttactcc tttatcacct
     8581 atttactgac ctagccaagc gagatactgt atgtctcact cctctaattg ccttgctcaa
     8641 tgcataaata ttatcgactg ttgccagtcc cccatatcct gcgtcaccta tatgttgaat
     8701 atcaactcca caaattttat ttctaagtgc aatttcctta atagtatctg tatcagatgt
     8761 ttcttggcta gtaccaatag cactcaatac aagaccaccc ttactatgaa cgagatcaac
     8821 gacttcacgc aactcttggt catgaaaggc tggaacggtt ccaactgctg gaacaagtat
     8881 cacatccgca cctgcttcca acaattgctc tgcgacagaa agctctgcca caggctcatt
     8941 cactcctgcc ccgtgcatct tacctgcaat aatcaaacca gaaaagtttt ccttagcagt
     9001 ttgaacagcc ttaatgattt ctcgattgct aactcctgtt ccaggatttc cagtcaaaca
     9061 gacaaagtca aaacctaact cctctattcg cttcaatgtt tcaacactag caacacgacc
     9121 cgcaacaatt tcctgtgttt cctctagcat ctttgcagat gggtcaatcg gttccaaatt
     9181 tacaccaatt ggacaagcaa caagctggtg taagcgatga ataacatcat cacctgaact
     9241 atccaaagca taaattttag gctcaaaaac atcaacacaa ttcaataaaa tcatatcagc
     9301 tccaaaagct ctagcaattt cagaattagt tatatcccca acaaatgtct cacgagtaac
     9361 tacattttca gatagaacaa ctctaccttc acttgctaaa atactttgtt ttaattcttc
     9421 agcattcatc tgtaatatct cagatggatt tgcactaatt aaacgtttca ttctcaatcc
     9481 tccaataact taaaccgttt ttcaatagct attacaaatg gtaaataaag taagacatcc
     9541 aaaacaatca atacaatttg taataatgaa ccagaaatac ttcctgtagc aagtaaacca
     9601 cttataacag gtggcatagt ccaacctgga tctgtataag ttagcggaac caaacctgat
     9661 gccattgctc cccacgctac tagtaagtta aacattggag ctaagataaa tggaactagt
     9721 aacaaaatgt tcaaaacaat aggaacgcca aacattgctg gttcatttat attaaataat
     9781 ccaggtataa cagttatagg tgccaaagtt tttagttgtt tactagcttt cttcttatgt
     9841 gctaaatatc ctaacgcaag aactaaacct atggttgcac caccgccacc tatgaataca
     9901 aaattatcca taaatacgct agtaaaaata tttggaagag tttctccagt ttgataagct
     9961 actttatttg catctagatt agctaaccat aacggtttca taactgcatt aacaacattt
    10021 cctccgtgta atcctacaaa ccaaaaacta ctattaagga aaattaagat aagaagacca
    10081 ataacattat ttcctaaaag tccaagtgga cctcccaaag ctacttgagc aatttcatga
    10141 agattaggta aacttaattt atctaaagtt gcataaacaa tcaaccaacc aacaatagtc
    10201 actgcaccag gaataatggc actaaagctt ttagatactg ctggtggaac accatccggc
    10261 atttttatct gtatattatg atttataaac cattggtaga tatagccatt aatcaatcct
    10321 aaaatcatag caacaaataa accttttgat gccatgaaag cggtaggcat tcctgctcca
    10381 gcctctcctc taatgaaagg cgtaactgta ataaaagatg ataatgacac aataccagca
    10441 ggaataccat caactttgta ttgtctagcc ataaagtaag cgataccaaa actagctaca
    10501 agaccaagta atccaaaact actatcaaca cccttccata aatagtcagc aacaccaata
    10561 tcacccagat atttttccca tcctggaata ggaaaacttg caataaccat tagtaatgaa
    10621 cctatcaaca ataaaggtat agttagaata ataccgtctc gaatagaaac caacgcttta
    10681 ttattaccca atctagccgc tactggaagt aacttttctt gtaataattt ttccataacc
    10741 ttttcctctt aaatatattt tattatcaaa agttatcaat tatctttatt ttttgacgtc
    10801 aagttgttat ttgattatct tttgttattt atattttaca actataagaa agccttgtca
    10861 aggatttgtg taaatatttg attatttttt attatcaata tataataaaa agagaccagt
    10921 aagcaatgaa aagcttaaaa agattaacat ctacatttat ccatagcaaa aaatcatagg
    10981 attttaagaa tctgacaact aggaagaaaa ctaatatgac cttatctaag aaacaattac
    11041 aactacgagc taaaatactg gaaacagttt acacattagg tcccatttca cgaattgaaa
    11101 tcgctactaa aacaggaata acacctgcaa caactagcag tatcacaaat gatctgatta
    11161 aagaaaacat tctcttagaa cttggtgaag acgaacacga tacaagcgta gggagaaaaa
    11221 aaatcctgct agacattcaa gctaaacgat tttactacat tggttgtgaa ctatctgaaa
    11281 aacatttcac ttttgcttta ggagataatc taggaaatat cttaaaggaa gagaaagaaa
    11341 ttgttactaa acagttaatc caagaaaagg gaaatcaact cattagccag acactaaagc
    11401 aattcttaaa taactgctct gattatgaaa tagaagcaat tggaatcgcg ctacctggtc
    11461 gctatttaga tgattataaa ataacaacaa acaatccttt atggcaacat atcgacttag
    11521 aaatgattca atcccacttt gataagcctt tgtttttctc taacaatgtt aactgtatgg
    11581 ctataggtaa acgcctattt agtcgccaac agaatgaccc taattttgct tattttcatt
    11641 ttgctagagg tatgcactgt tcttatatct acgacggaaa catttatgga aaaggaaatc
    11701 taatgattgg agaaataggg catacagttg tttcatctga gggagaagaa tgtagttgcg
    11761 ggcgcaaggg atgcttacaa acttttgctg gagaatcttg gttaatcaaa aaatcaaaaa
    11821 ttctatatca tcaatctccc tattctctac ttcctagttt agtcaaaaat gccgatgata
    11881 ttgatatcca agttatttta accgcttatc aattaggtga cactggaata atcacactta
    11941 tccatcaagc cttactctat cttagtcaaa ccattttaaa tatcagtatg atgattgact
    12001 ctcaaaaaat ctacctacat agtcctttac taacaaatca acacatcatc caaaaactat
    12061 atagtgaaat gaactacaaa cccaaactgc tctataatcg cctacctgaa gtcattattg
    12121 aaccttacaa tgattttaca gccgcacact cagctattgc actttgtttg tatcatacaa
    12181 ttctacattc ctaattttct attacattta ataaataggc taaaaagagg gagtatatca
    12241 taaaaagcga acaaacctgt tttctgaaaa tcagaattct gttttgttcg ctttctttat
    12301 atttggaatt atactcctat ctcccctttt tcataatgta tagtaaaatg aaataataac
    12361 aggacgaatc gatcgggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt
    12421 actattctag tttcaatata ctatattttc gtacaggtgc ttcaaccatt tgaacgattt
    12481 caaatccttc tttttggtaa agattctgag ctctttgatt tgcctcgaag acatttagag
    12541 aaatactata tatatcttca ttttcaaagg ccaaactaac aaatttcctt aaagcctggc
    12601 tacctaagcc ttgctcctgt ttctgggggt tgataaaaaa tctcccgata tgaagattgc
    12661 tgtcttctag cctgattttc tggataaatc ccacaaactc ttgttcatca aagattgaaa
    12721 agactccttc caaggcttga agggtcagta gaaaaggaat ccttggtccc atccattgtt
    12781 cttgaaagga tttgcctagg gagttggacc actggcatac aaattgagcg ttttctatac
    12841 tcaccttttc ttcaaaacga attgtcatct tttcctcacc atcttatcta tgtttctcca
    12901 ttatactatt tctcccattt tttacgaata gataagtatg attgattttt atttttttct
    12961 cgtcgggagc attctcgctt cctttcttgg tttggtcatt gaccgttttc cagagcaatc
    13021 cattatcagt tcagtcagtc actgcgattc ctgtcagact cgcttgcgtc ccttagattt
    13081 gattccgatt ctctcacagg tcttcaatcg cttttgctgt cgctactgca aggtccgcta
    13141 tcctgtctgg tatgccctct ttgaactagg cttaggactc ctctttctgc tttactcttg
    13201 ggagttgctt tccttggggc aagtcgtcct aatcaccgct ggtttgacct tgggtatcta
    13261 cgactttcac catcaggaat atcccttact ggtctggatg actttccacc taatcctaat
    13321 agcttcctct ggctggaatc tggtcatggt ctccttcctc atacttggaa ttttggctca
    13381 ttttatcgat atccgcatgg gtgcagggga tttccttttt ttagcttctt gtgctctcgt
    13441 ctttagcgta acggagttac tgatcttgat tcagttcgct tctgcgacgg gtatcctggc
    13501 ctttctcctg caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac
    13561 ttgtttgatt atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct
    13621 tggtggagag cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag
    13681 cgttccagat cggcttgact agatacacca aaacctgtca agactgggat gtcggccact
    13741 tgatgaagtt gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtc
    13801 actccattga tggcaacggc atagatgaat ccctccgccc cttcaatcaa ctctttctgg
    13861 cgctcaattc ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa
    13921 aatggttcta caaagttggc atgttcatga ggcaagtctg ggataatcaa gcccttcaca
    13981 gctgtatcag ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag
    14041 taggtcatga tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc
    14101 tgggtagagg tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct
    14161 gcaacagggt ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa
    14221 aagtgaattg tttcagcaag accgtccaaa cctttctcgt ggtcaccagc catgatatag
    14281 ggaacaaaaa ttccttttcc agctgcttta atagcattca atttttctgt tagtgtctta
    14341 ggcatgagct tctcccttct ttgctgcatc tgcttccaag cggtctttga cttgaaccac
    14401 atccttgtcc ccacgacctg ataggcagac aatcatagac ttttctggtc caagttcttt
    14461 ggccaatttc accgcaaaag cgatagcatg gctagattcc aaggctggga taatcccttc
    14521 cacacgagac aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct
    14581 ggcacgtttg atatcgtggt agtgagaatg ttctggacca ataccaggat agtccaaacc
    14641 tgctgagata gagaaggctt caagaatttg accatgggca tcttggagca catccatgag
    14701 agaaccgtga agaacacccg gacgaccctt ggtcaaggta gcagcgtggt gctctgtatc
    14761 cacaccaagc cctgctgctt cagttccata catagctact gactcatctt ctacaaaggg
    14821 atggaagagc ccaatagcat tagatccacc accaacacag gctactagag catcgggcag
    14881 attttgacct gtcatatcgc gatactgttg tttagcttcg cgaccgatga cactttggaa
    14941 gtcacgaacg atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt
    15001 atcgtcgata ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg
    15061 cgaaccatct gttacagcct cgaccttggc tcccaaaagc tccatgcgga agacattgag
    15121 ggcttggcgt ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc
    15181 cgcagcagtt gcagttgcca caccgtgctg accagcaccg gtttctgcga taattttctt
    15241 tttacccatg cgtttggcaa gccaaacttg tcctaaggca ttgttaatct tgtgggctcc
    15301 tgtatggtta aggtcttccc gtttgagata aatcttggct ccgccaatat gctgggtcaa
    15361 gttttttgcg tagtaaagag gagtttcccg ccccacatac tggcgcaaga gttggtttaa
    15421 ttcctcttgg aaacttgggt ctgcctgact ttcacgatag gccttctcca actccaaaac
    15481 tgctgtcatc aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt
    15541 atttggttcc tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat
    15601 ctttttgtcc atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt
    15661 gaattgcttt tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta
    15721 gtccagtcgt atccagttga ccccaatcaa agggctggcc acttcctgcc acaggggcat
    15781 caaagagtag ataatctgcc tgagaattag ggacatgccc atttccatct acctgcacag
    15841 cctgaatact ggcacaaggc aaattttcaa ataaatcatc tgccacctga ccgtgaactt
    15901 gaaccaagtc caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa
    15961 caaatactcc aacctttttc acatctacag gaataagctt tgccaactca gctgcctctt
    16021 ctaaagtcac ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg
    16081 aaacggctgt ttccgccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc
    16141 tgcaactcct tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa
    16201 attccgttaa agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca
    16261 gaaatgtaat agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg
    16321 acctcaaagg tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg
    16381 gctacctcta gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc
    16441 gcgtagtcat acagttcctt gaggcgttct tcggacaagg ctgccacaat gagcaagata
    16501 actgtcgcac ctgcattgcg agcgcggatg atttgctttt catctatgat aaagtctttg
    16561 ttgagcgtcg gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta
    16621 aagaaaacct catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg
    16681 gcctgttgca caatatccac atcgagattg atatctccca aactagggct agctttcttg
    16741 acctcagcga ttacctgcaa gcggtcctga tgattcttca aaaattctgc caagcgatag
    16801 gtctggcgca gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc
    16861 tctaagattc gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt
    16921 tttcaagggc cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc
    16981 tatcaatctt accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga
    17041 atggacttgc ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc
    17101 caccacgaat atcttccata gcatagcctt ccattcccaa atcctctgga gtaaagcttg
    17161 acaagctgat ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt
    17221 catccaaccc ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa
    17281 cctgagctgt actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag
    17341 ccattggatg aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac
    17401 gagctggcat gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc
    17461 cagttttatc aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg
    17521 cttcgaggac atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca
    17581 tgtgaatacc gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag
    17641 acttgtcccc acctgtacca cagttgtcca tggcatcatg aatctcagtt ggaatatgct
    17701 gggcatgtcc tctcatgact tgggcaatgg ctgtgcgttc ttcaggtgtt tcccccttca
    17761 tcttaagagc taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac
    17821 gctcaatgac atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa
    17881 taatctcttt catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa
    17941 gacaagccgt ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg
    18001 tttttatgtt gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag
    18061 tcttctggca tttcctcaat caaaatactg tgataacgca tgaccgcacg tccttcctca
    18121 ataccttgat acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg
    18181 acttttggag ccaaacctag cttaccacca aagacttctg caatggcttg gtggcccaaa
    18241 caaatcccaa gaatcggctt cttgcctgca aaatcacgaa tcatgtcttc catctttcca
    18301 gcatcaactg gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct
    18361 tcatacagct tggaatcatc atttctcaga acctgaactt ctgcaaaatt cccaatgtat
    18421 tgggccaagt tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt
    18481 ctccaattct agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga
    18541 tagagtcgta gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca
    18601 tggttcggat ggcaatggcc aaatccatat cactcgtcgc agacaagtag ccgattgctc
    18661 ctgcatatac gccccgtttt tccgtttcca gttcatagat gcgtctcatc gcccgaatct
    18721 ttggtgctcc agaaacggtt ccagcaggaa gtgtagcttt caaggcatcc atggccgtga
    18781 gttctggaag caaacgcccc ttgaccacgc tggtcaaatg catgacgtag cggaagagct
    18841 ccaccttcat atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt
    18901 tacgccccaa gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt
    18961 cagtcgccaa ggtcttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg
    19021 gattggttgt cacgatgcca tttttgacag aaactaaact ttctggacta gctccgatga
    19081 tttgataatc cccaaaatca tagaaataaa ggtaattaga aggattagtc acgcggagat
    19141 ttctgtagaa gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac
    19201 attggaacat atcgccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact
    19261 tatgtggagc gatatgcggt ttgaagtcta acgaagatag atccaagtct tcaaattcat
    19321 ttggagcagg aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt
    19381 gactgcgctc actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa
    19441 agaccatata gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag
    19501 ggatttgacc aatttcttca taaagcgaaa tcatatcgta acccaaaaaa ccaatggctc
    19561 caccaccaaa agggagctct gagtggtgct gactcttatg aatcacttca taaaggaaat
    19621 ccaagggatc ccgatcaatc acttgaccat tttgatagag aaccccattt tcaaacttaa
    19681 tctcaaaaac tggattatag gctaggatag aaaaacaagc tgtttccttg tctctcggaa
    19741 tactctctaa aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata
    19801 agacatctcc atgaatgatt cgttccattg taatttccct ttcagttcta cttctagtcc
    19861 gtggtgactg tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt
    19921 gccacctcaa ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac
    19981 aggctgtgcg ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga
    20041 acccaacttt acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa
    20101 gaactgtaat ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg
    20161 tccttgcctc cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata
    20221 ctcttcgaaa atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat tggttactga
    20281 cttcgtcagt tctatctgca acctcaaaac agtgttttga gctgacttcg tcagttctat
    20341 ccacaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgttctttga
    20401 ttttcattga gtatcactag cttttttcgt attagtccag ctttttgttt gcttttagta
    20461 gtaggcaagg atctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa
    20521 agataaacca aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg
    20581 cgttggtaac gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg
    20641 tttaacaaca agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt
    20701 ttcaaaatca gcccactttc actacttcca accacctatt cacaatcacc acaggctccc
    20761 tgaagatcaa aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt
    20821 ctttgtcaag acttttttac gatttttttg aaaatatcat tcgaatgtga ccatgtcttc
    20881 cttagatcga acatgaacat gtcccacttg ttagaaattg gatccaactc aatagaaact
    20941 gaatggaggc taaacagaac ttattttaga acactccatc ttttccacta ggattttcaa
    21001 gaattaaaca atactagaaa ctctgtctcc taacaaattt aggagaaact tcaacagatg
    21061 tgacactttc ccctttaata attgctaaaa caccttctat catttcttta gccaatttaa
    21121 cataattggg agcaattgta gacaaagctg gagtataata ctgagaaata ggaatattat
    21181 caaatccaat gatagaaata tcatctggaa taagaattcc tttctcatag cacgcacgaa
    21241 tcaagccctg aaccttttca tctcctgaaa caaaaataat gtccggataa ttttgggtag
    21301 tcaagtgctg cattgcataa gaataaactg aatcaattgt agataagcca taaatgactt
    21361 ttaaatccat aaagtaattt ttatcattca gaaaagaacg cacacctctt tcacgatcct
    21421 tattaacatg ggattctcct cccataagca accacatatt tttaaatttt tcttcagtta
    21481 cagctttcat catatcataa gtagcttgaa aattattatt agatacatag actactccag
    21541 acgtttgaga ttcaccgaaa acaagaaaag gcatatggtt cttctttaaa tactgaattc
    21601 tgatatcatc tacactttca taaaaaacaa taacaccatc tactaggcta cctgtgcttg
    21661 atataattga attactaatt gtatcctcct ctccaaagta ctcaactata gcattaacac
    21721 caaattcttt acacgtccgt aacactttat ctaacagcgt atgaaaccaa attaaaggaa
    21781 aagagtcgat tttttttaca gaaatcaata tatttatagc ttctttttta gttaaatttt
    21841 ttgcatacgc atttggaata tacgacaatt cctctataac tttttgaatc gcttgataag
    21901 tttcttcttt aacatttact ccaccattaa taactcgtga aactgttttt ggagaaaaac
    21961 ctgataaacg tgcaatatca taaatagtta cctttttccc atttatattt ttcatttcag
    22021 tcctccatta cg
//
LOCUS       DAVLHB010000033        21809 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLHB010000033 DAVLHB010000000
VERSION     DAVLHB010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.033"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            295..447
                     /locus_tag="VXE36_001410"
                     /pseudo
     CDS             295..447
                     /locus_tag="VXE36_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            603..941
                     /locus_tag="VXE36_001411"
     CDS             603..941
                     /locus_tag="VXE36_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV0779704.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            1131..2615
                     /locus_tag="VXE36_001412"
     CDS             1131..2615
                     /locus_tag="VXE36_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0779705.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFAAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVEYAKQTEIILSLFSILG"
     gene            2619..2858
                     /locus_tag="VXE36_001413"
     CDS             2619..2858
                     /locus_tag="VXE36_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV0779706.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMQVIDIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2988..3302
                     /locus_tag="VXE36_001414"
     CDS             2988..3302
                     /locus_tag="VXE36_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV0779707.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3420..5399
                     /locus_tag="VXE36_001415"
     CDS             3420..5399
                     /locus_tag="VXE36_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0779708.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDATERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5409..5723
                     /locus_tag="VXE36_001416"
     CDS             5409..5723
                     /locus_tag="VXE36_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV0779709.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5754..6275
                     /locus_tag="VXE36_001417"
     CDS             5754..6275
                     /locus_tag="VXE36_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779710.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKFINEQIRLINNLSN
                     WKRTHLVYNPDLV"
     gene            6339..7685
                     /gene="celB"
                     /locus_tag="VXE36_001418"
     CDS             6339..7685
                     /gene="celB"
                     /locus_tag="VXE36_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV0779711.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVF
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            8065..8241
                     /locus_tag="VXE36_001419"
     CDS             8065..8241
                     /locus_tag="VXE36_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779712.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8642..10855
                     /locus_tag="VXE36_001420"
     CDS             8642..10855
                     /locus_tag="VXE36_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0779713.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(11077..11553)
                     /locus_tag="VXE36_001421"
     CDS             complement(11077..11553)
                     /locus_tag="VXE36_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0779714.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11776..14979
                     /locus_tag="VXE36_001422"
     CDS             11776..14979
                     /locus_tag="VXE36_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0779715.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVSIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISVSKALQKGAWKDINEGQSDKEVENEFLTISQVHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIDNNETLQSVYDAKQGVWGIVKYDDSVSAISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            15360..15745
                     /gene="tnpA"
                     /locus_tag="VXE36_001423"
                     /pseudo
     CDS             15360..15745
                     /gene="tnpA"
                     /locus_tag="VXE36_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(16124..16753)
                     /locus_tag="VXE36_001424"
     CDS             complement(16124..16753)
                     /locus_tag="VXE36_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0779716.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16763..17764)
                     /locus_tag="VXE36_001425"
     CDS             complement(16763..17764)
                     /locus_tag="VXE36_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0779717.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSIDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17795..18436)
                     /locus_tag="VXE36_001426"
     CDS             complement(17795..18436)
                     /locus_tag="VXE36_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0779718.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVICGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18455..19270)
                     /locus_tag="VXE36_001427"
     CDS             complement(18455..19270)
                     /locus_tag="VXE36_001427"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0779719.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19542..19976
                     /locus_tag="VXE36_001428"
     CDS             19542..19976
                     /locus_tag="VXE36_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0779720.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFELGI"
     gene            19988..21178
                     /locus_tag="VXE36_001429"
     CDS             19988..21178
                     /locus_tag="VXE36_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0779721.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            21189..21680
                     /locus_tag="VXE36_001430"
     CDS             21189..21680
                     /locus_tag="VXE36_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0779722.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21695..>21809
                     /locus_tag="VXE36_001431"
     CDS             21695..>21809
                     /locus_tag="VXE36_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates concomitant with their translocation across the
                     cell membrane; protein IIA transfers a phosphoryl group to
                     IIB which then transfers the phosphoryl group to the
                     sugar; IIC forms the translocation channel for the sugar
                     uptake;involved in N-acetylgalactosamine transport;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0779723.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGV"
BASE COUNT         7031 a         3460 c         4556 g         6762 t
ORIGIN      
        1 tactttctta ctaaattggt gcaattgaca cagttgttgc gactttagtc gcttacaaat
       61 gtggctgcaa cctgacaagg tcagttgcct caaaacgtta atcaatacga ttatatcaac
      121 gtttcaaagc actcaaaagt ttaccttatg ggtgcttttt tcgtgttttt ttgaaaagtt
      181 taccttattt ttatagtaat gtgaaataag aataggacaa actgaggata gtcaaatcga
      241 attctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta ctatattatg
      301 gataatgcaa gattccatag aatgggtaag ttagaactct tgtgtgaaga gtttgggcat
      361 aaacttttac ctcttcctcc ctactcacct gagtacaatc ctattgagaa aacatgggct
      421 cttttgtcct gctcttgttt caattgacta taaatcgcta taagaaaaaa tcattttatt
      481 ggtataaaga agtgattgaa agtaatggcg aaacgttaga taattagttc ataaaaaaca
      541 agtttagatc ctcatctaaa cttgtttttt taaaattgaa ggatgatttt gaaggatata
      601 agatgacatt gactattcat gtatattata aaggtgatgg agatagtgca ataaagtttg
      661 caagagaaat gcttgatagt ggccttgttg aagaaattag aaatcaaaaa ggtaacttga
      721 aatacgaata ttttttacca attgaaaaag agggaactat tctccttatt gatcagtgga
      781 taaatcaaga agctttagat gaacatcatc aatcaaagac aatgcagaaa atcttagatt
      841 taagaaaaaa atatcacttg cagatgcaag ttgaacgtta tatagaagat gattctggga
      901 tgccagaaag cgataagtcg tttatagaca cagggaatta gaattattgt gagagttttt
      961 gtagtttgaa agtattgaaa atcgtaaaga tatcattacg agaatacaag aagatattgt
     1021 tctatttcca ttaaaaatta cttctttcct taacaataag gaaaaagaat gcgttttcat
     1081 cttttggttt gaggtttata ataagagtat caaagtcagg aggaaaaaag atgactactt
     1141 ttaaagatgg atttttatgg ggtggtgctg ttgctgctca tcaacttgaa ggtggatggc
     1201 aagaaggtgg caagggaatt agtgttgctg atgttatgac tgctggtcgt catggagtag
     1261 ctcgtgaaat tacttcggga gttttagagg gtaaatatta tccaaatcat gaggcgatag
     1321 atttttatca tcgttataaa gaagacatag cactttttgc tgaaatggga ttcaagtgct
     1381 tccgtacctc tattgcatgg acgcgtatct ttccaaaagg tgatgagtta gagccgaatg
     1441 aagaaggatt acagttttat gataatcttt ttgatgaatg cttaaagaat ggtattgaac
     1501 ctgtcatcac tctatctcat tttgaaatgc cttatcactt agtgaccgaa tatggtggtt
     1561 ggaaaaatag gaaattgatt gatttctttg ctcgttttgc agaagtcgta tttaaacgtt
     1621 acaaagataa ggttaaatat tggatgactt tcaatgaaat caataatcaa gcgaattatc
     1681 aggaagattt tgcaccattt actaactcag gtattgtata tgaggaaggt gataatagag
     1741 aagcaattat gtatcaagca gcacattacg aattagttgc ttctgcacga gctgtaaaaa
     1801 ttggtcatga gattaatcca gattttcaaa taggttgtat gattgcgatg tgtccaattt
     1861 atccagctac ttgcaatcct aaggatatct taatggcaat gaaagctatg cagaagcgtt
     1921 attattttgc tgatgtgcat gttttaggta aatatcctga gcatattttc aagtattggg
     1981 aacgaaaagg tatttcagtt gattttgctg cccaggataa agaagattta cttggtggga
     2041 ctgtagatta cattggtttc agttactata tgtcctttgc tatcgactct catcgtgaaa
     2101 ataatcctta ttttgattat cttgaaacag aagatttagt gaaaaataat tatgttaagg
     2161 cttctgaatg ggagtggcaa attgatccag aaggtttacg ttatgcgtta aattggttta
     2221 cagaccacta tcacttacca ctctttattg ttgaaaatgg ttttggagct atagatcaag
     2281 ttgcagcaga tggtatggta catgatgatt atagaattga atatctaggt gcccatattc
     2341 gtgaaatgaa aaaggctgta gttgaagatg gtgttgattt aatgggttat actccatggg
     2401 gatgtattga tttggtttca gctggtaccg gtgaaatgcg gaaacgttat ggttttattt
     2461 atgtagataa agatgacaat gggaagggaa gttataatcg ttccccgaaa aaatcttttg
     2521 gctggtataa ggaagttatt tcatctaacg gtgaatcagt agaatatgct aaacaaactg
     2581 agattattct cagtttgttt agcatattgg gatgacatat gattggaagt attgcagcaa
     2641 ttttaacaac atttgcattt ttaccacaag tttttcgtat agttaagaca aaggacacag
     2701 gatctattgc tctaggtatg tatgttatgc aagttattga tattgcattg tggcttgctc
     2761 atggtattcg tataggagac ttgcctttga ttttagcaaa tagtgtttca tttctactct
     2821 caggaataat tttattttat aaattgaagt ataaataatt tttttccata tcatttagga
     2881 aaatgaggga attgtcattg gaaacgcttt attttataat aaaaatagat aacagataag
     2941 tcaacttagc acagctttga ttggatttaa gaaaaggaga aaatattatg gcaaaagctt
     3001 taattatttg tgcagcagga atgtcttcat cacttatggc acagaaaaca acagagtttc
     3061 taaaaggaaa agggaaagat attgtagttg atgctattag tgctactgaa ggagggaaag
     3121 ctatcgcagc agcagctttt gatttgtatc ttgtcagccc tcaaacaaaa atgtacttta
     3181 agcaatttga agaggctggt tctaaagcag gaaaaccagt tgtacaaata cctcctcaag
     3241 cctatattcc tattccaatg ggaattgaaa aaatggctaa tttgattctt gagaatattt
     3301 gatgaacaca tgaaatgtca ataaatattt aagttaagat aaattgtttt gagtttgata
     3361 taaattgatt taagtgtata atatgcttca atatatgaaa acatacgttt taggagggaa
     3421 tgaatgtgtt aaacattaaa gagaaagata tccttcaatt tttaataaaa aataaggaac
     3481 gttttgttac aagcaaagaa ctggcagaat atttatcctg ttcagataga actgtccgta
     3541 atgtactgaa attaattgag aagacaatga ttattcaagg agtccggttg atttcaaaac
     3601 aaggtcaagg gtatcaaata ttttttgaga atcaaggcgc ttaccaggag tttagacaaa
     3661 cttatgaact ggaagaagac tatacgaaaa ctgcggtttc aaaaggtgat gatcgtttag
     3721 tatttatctt aaataaatta ttatttgagc aagttccagt tctttttgat gatttagctg
     3781 atgaacttta cgttagccgt tcaacattat ctcatgattt cagaaagata cgagtgatgt
     3841 tatcagagta taatttgtcc attgagagta gggcgaataa aggagtttat gtctcaggcg
     3901 aggaacgtga taaacgacgt tttatcataa attatttcct agagaatcaa ttttttaaaa
     3961 caatacattg ctatgtaaaa tttaactttt ttgatcaaac tgttccatta gaagaatttg
     4021 ctagaattgt tttggatgaa tgccaagagg ccaacctaaa actatctgat tttgtactac
     4081 agaacttagt agttcacata gcattgtctg tgattcgttt aaaatccgga tttgaaataa
     4141 aaaatataga ctgtcagatg actgatgatg caacagagag aaaggttgcc caaagaattc
     4201 tttctaaagt aagagaagta acaaatcagg aatttccagt tcaggaaata gactacatta
     4261 ctttgcattt gttagctaag agtcaacaat gtcaaaaaaa tcagaagaat atttctgaag
     4321 aagttttaaa aaaatcttta tttaaaacat ttcagaattt aggattagat gatatgtata
     4381 acttttcttc agatttccaa ctaattgaag gattgataac tcatctaatg acactacaag
     4441 tacgtttaga aagccggatt accttaaata accctttagt agatgaaatt aaacagaatt
     4501 atagtgatat attctttatg actagagaaa ttcttgcaaa tatggacaag ttcttggagt
     4561 ggacaatatc agatgatgaa gtagcatatg taagtcttca ctttttagct gctatggaac
     4621 gtagcaaaga gagtactaag tttaatattc ttgctatttg tgcaacagga tttggtgcag
     4681 cccaaatgtt aagaaatcgt ttggaaacgg agtttgggaa gcgagtagaa gttgttgatg
     4741 taataggcta ttatgaattg aatcaagaaa aacttaaagg aatagatttt atagtgtcag
     4801 ctgttgattt atcaaatcta tattttcaaa tcccagtttt taaagttagt gtgtttctta
     4861 agagtgatga gatggaaatg attagaaaag ctatggatca gatgcaagtt tctagttatg
     4921 tacaatcatc aaagattaat aaatttgaaa acaacagctt tagacagtat tttagtaaag
     4981 aaaatttttt aatatgtact gaatcagaca aggtaaattt acttgaaaag atggttgaga
     5041 gtttatctgt tggtgaatca aatgagtttg aacaatcttt actttatgga attaaacagc
     5101 gcgaagaatt aagttcagtt gttttttctg aaaaaattgc agttccgcat cctattcagc
     5161 cctttggtac agagggaaag gtttcggttg caatttgtaa agattcgtta ctctgggata
     5221 atcaaagttc acatgtccag ctagtatttc ttctatctcc atcaatatat gggaacgaag
     5281 gtttggcaac tgtgactaaa aagatagtct ctctgacaga gaatgatgaa ttgcaaaatc
     5341 agctaatatc ttgcaataac tttgaagatt ttattaacat atttgagaag ataaaatagg
     5401 aggttcatat gaatcaagag gaactgcagg ttgcagcatt tgaaattatc ctgcattcgg
     5461 gaaatgcaag gtcagaaata catgaagcat ttgcaaaaat gagagaaggt agttttgatg
     5521 atgcagaaag taaattaaat caatcaaatg agataattct tgaagcgcat catgcacaaa
     5581 ccaaactctt gcaagaatac gcaagtggag tggaaattaa aattgaaatt atcatggtac
     5641 atgctcaaga tcatttaatg accactatga cattattaga agtagcaaag gaaatgttag
     5701 ctctttataa gaaagttaac taaatatgtg ttgttatata aggaggaaat gatatggata
     5761 aaaaagaacg acaaaagatt gaacaacaac gtcgagagat ggctctaact aatacttttt
     5821 ttaatcgata tcttcttcta cgttattcaa tagcactctt cttttttggg aatatttatt
     5881 ggcttttgaa tcagtttatt agtccctcgc ctattattat tttccccatt atgctcatag
     5941 tattttctat tttagcaact attgaacaat ttaaacttta tggaaatagg aaagaaaagt
     6001 tgggaataac actaatgttt gttagaatac aaatacttat ttcaatagga ttacttgttt
     6061 taacttggac aagttggttt aagaatcttt ttccgatttt tgaaaataac caagtagcac
     6121 gtttatttgt ttttgtagtt cttctattag gtttagttct gagtttgtta gacattagaa
     6181 gaattaaaaa atttataaac gaacagataa ggcttatcaa caatttgtcc aattggaaaa
     6241 gaactcactt agtttataat cctgatctag tataatttgt atttgaaact agtctttaga
     6301 aagtaaaaat tattatgttt tattaaggag gtctatttat ggatcaacaa aacgggttgt
     6361 ttggttttct tgaaaaccat gttatgggac caatgggcaa acttgctcag tttaaagtag
     6421 tgcgtgctat cacggctgca ggtatggctg ctgtaccatt tactattgta ggatcaatgt
     6481 ttttggtatt cagtattttg ccacaagctt tctcattttg gccaattgtg gcagatattt
     6541 tctctgcttc atttgataaa ttcacatcac tttacatggt tgcaaactat gcgactatgg
     6601 gttctctatc tctttatttc gttctatcac ttgcatatga attgacaaaa atttatgcag
     6661 aggaagaaga actcaatatg aatcctctta atggtgcctt gcttgccttg atggcttttg
     6721 tcatgacagt accgcaaatc atttttgatg gtggaatgat gaagactgtg acaagtctaa
     6781 aagaaggtgc agtaattgca gatggatggg caatgggaaa tggagtcgca cgttttggga
     6841 caacagggat ttttaccgca atcattatgg caattgtgac tgttcttatt tatcgtatgt
     6901 gtgttaaaca taattgggtt attaaaatgc ctgaagctgt tccagaagga gtttctcgtg
     6961 gatttaccgc tttggttccg ggatttgttt ttgcatttgt tgttatcttt atcaacggtc
     7021 ttcttgtagc aatgggaaca gatattttta aagtcattgc aattccattt ggttttgtat
     7081 ccaatctgac taattcgtgg attggtttaa tgattattta tctattgact caactacttt
     7141 ggattgtagg tatccacggt gcgaacattg tttttgcatt tgttagtcca attgctcttg
     7201 ctaacatggc tgaaaatgct gctggcgggc acttcgctgt tgcaggtgaa ttttctaata
     7261 tgtttgtaat tgcaggtggt tctggtgcaa ctttaggact atgtttatat attgcttttg
     7321 cctctaaatc tgaacagctt aaagcaatag gacgagcatc tgtagttccg gccttattta
     7381 atattaatga accattaatt tttggattac ctattatcta taatccagcc ttggctatac
     7441 catttatttt agcaccaatg gttactgcta ctatttatta cgtagcgaat tctctaaact
     7501 ttattaagcc aattatcgca caggttccat ggccaactcc agtagggatt ggagctttct
     7561 tagggacagc agatcttcga gctgtattag ttgctctagt atgtgcattt gcagcattcc
     7621 tagtctatct tccattcatc cgtgtatatg atcaaaaatt ggtgaaagaa gagcaaggta
     7681 tctaataagt aaaaaagtat actcgatgat agaatccata tagtttaaat aatgagtgtt
     7741 aatattagca gtgaagaggt ctttttaaga tattcttctc ttctttttca tattttttcg
     7801 ctatgtaggg tatgaagcaa aatagaaagt agttcgaata gttgataaac aggaaactgc
     7861 tgttatttaa aaaaaacaat aaagtaaagt atgttatcgt agaatacgat acaatagtaa
     7921 aaaagcaaaa agaatgcgtt ttatatttgg gtttgaggtt tataaaatag gataagcgtg
     7981 ctgaaaactt agatatgaca aacaaaataa aatttttaaa agctacatag aaacatggta
     8041 taatgtatct aaaggaggta gcatatgtcc ttagatatag ataaagaaaa gatgacaatc
     8101 atgggaatag cttttgaaaa cagatccgtt tttaagagtg tttggtatgc tttaagtaca
     8161 aatatgattg aaggatggcg acctacggtt agtgatgttg aaaaattacg agatgaagct
     8221 cttgctctgg ggatgactta atgaagcgca actgttatga gtcttatgac tatgttgatc
     8281 cggataattt atataccgat ccgggttctt cagttctaag aaataagcag gaaggaaaaa
     8341 agcacgcgag cttgaatatc gtatgattgc tagtaagagt ttgaaattat ttatcaatcc
     8401 tatcttagtt aatagtttaa aagtagtttg tttcacaact gcataagctt agaaaagttg
     8461 aaaagtgata actctttaat aaactcttgg tttgttaaaa gatattttgt ccactacatt
     8521 ttttcaattg actattattt gtcatagata taacagatag aacattgcat tcagaataat
     8581 gaaaaacgca tcaaaaatgg tgcgttctgt ttttatgcta ccataaaagg aggaaaacaa
     8641 attgaaaatt tttaagggag agttttatcg aatctctgta ttaacagaca agctagtaag
     8701 gttagaatac tctcaaactg gaagttttga ggatagaacg acacaactta tctataatag
     8761 agattttggc caagtttcgt tagattatat cgagacatca aacgtactag atattatgac
     8821 ggactatttt catctgcact ttaataaagg agaatttaac gccgaaaatt tatttataga
     8881 attaaaagga aattttgccg tatatggtag tcgctggtat tttggtgaat ctattgaaac
     8941 gttaaaagga acagctcgga ctctggataa ggcagatgga gcaatctcgt tagaagatgg
     9001 aattattagc cgaaatggta tagccttatt ggatgattct caaggattta tttgggatga
     9061 acaatctggt tatattgaga gagaaaatca aattgacctg tatttctttg cctatgggca
     9121 tgattataga ggagcaatca gagactttta ccatttgact ggttcaacac ccttgttgcc
     9181 aagatatgct ttaggcaatt ggtggagtag atattggcct tatacgtcgg atgaatattt
     9241 ggatttaata gacagatttg aaacagagaa aattccatta tctatcggtg tgttagatat
     9301 ggattggcat ataactgaca ttccagctcg ttttggaagt ggctggacag gatatagttg
     9361 gaatagaaac ttaataccaa atccagaaca gttattgcaa caacttcatg atagaaagtt
     9421 aaaactctcc ttaaatgtcc atcctgctga tgggatacgg gcttatgaag aagcttatcc
     9481 tcaaatcgca aaacggttgg ggttaaatgt agaactagaa gaacctgcta tttttgattt
     9541 ttttaatccc tcttttaggg aagcctactt taaagatgtt cattatgagc tagaaaagca
     9601 gggagtagat ttttggtgga ttgactggca acaagggaca caaggtatgc tagatccact
     9661 ttggctttta aaccattatc actatcagga tagttgtaaa aatgcagaag gtggtttgat
     9721 tttatcaaga tatgcaggtc ctggtagtca ccgctaccct gttggttttt caggggatac
     9781 tattattagt tggaattcct taagatttca accctatttt acagcgacag catctaatat
     9841 cggttatagt tggtggagtc atgatatcgg tggacatatg ttgggggatt atgacgaaga
     9901 gctacaaact agatggctac agtttggtgt ttttagtccg attactcgat tacatagttc
     9961 tagaagtcct tttaatagta aagaaccttg gtttttttca gaaacaacat ctaagattat
    10021 gaagaaatac cttcgtttga gacatcagat gattccttat ctatatacca tgaatgtaaa
    10081 gacacatgag gaaggtgccc cattaatcag tccaatctat tatttctatc cagagaatga
    10141 tgagagctat aatgttccaa accaatactt ttttggaaca gaactgatgg tggctcccat
    10201 tgtagaaaag atggatttga cattccaatc tgcaaaagta gatgtatggt tccctgaagg
    10261 tgaatggtat gacttctttt cagagaaaaa atacacaggt ggtgtgaagt taagtgttta
    10321 tagggacatc tcgactacgc ctgtgtttgc aaaaagtggt gcaatcattc ccttggttgg
    10381 ttctgagata ggtatgggtg ttgatttacc tgaggttgta gattggtatg tattcccagg
    10441 gaaacaacat tcttttgaaa tgcttgaaga tcaaaatggt caaagatata aaacaagatt
    10501 atcaatcgat tgggaaatgg gaatggtaga gttagcatta caaggagatt ctagtatcgt
    10561 tccaagcaat agaaaacata gaattcattt taaaggaacg aatgtgtcta taattgaatt
    10621 gccaaataag aatgatacag ctaaatttga atggaaagat aataaaagga catctttaaa
    10681 tgacgaagtt tttagactac taaagacagc ttctcttcca tatgaattaa aagatagatt
    10741 gttaaatcaa ttcatcaatg ccaaaaactc tcatgactta atgaatatct tgcatcatca
    10801 ggataaggaa ttgagagggc gtttgttgga aatgatattt actagccaaa actaattgaa
    10861 acaattagaa agtcatttgt ttagtgtata tgaagattct gtatggtatt cgttatcact
    10921 ggtcacattg aaaatgtgaa ataagcacct acaacataga ctttacaaca cttcatgttt
    10981 catatcatgg ggtgtttttc tatttaagtc aaagccaatc aaaaaatctc actattcatc
    11041 aggttaaagg aaacctaatc atagtgagat tgtgaattat agtagagttt gtatcgcctc
    11101 ttcaatttgt tttgggtctg tttttgaaga aaagcgttca aagacttgcc catctcgacc
    11161 gatgagaaac ttagcgaaat tccattcgat tcgttttcct agtgggccag atttctggtc
    11221 ttgtaaccag acatagagag ggtctgcttc cttaccgttg accttaatct tggcaaaacg
    11281 tgggaaggtg gtttgaaaat gtaggctaca gaaggcgttg atttcctctg cgctgccggg
    11341 tgcttgtccc ataaactgat tgcaagggaa atccaatatt tcaaagccct gatcttgata
    11401 gcgttcatag agttcttgaa gtccctggta ctggggcgtt aaaccacatc cagtagcagt
    11461 gttgacaatc aagagaactt tgccacgata gctatccaag ggagttgctt ggttgttttg
    11521 gttcaaaacg gaaaaatcat aaagtgaagt catgagggcc tcttttcttt ttctacattg
    11581 taacagtttt tacttttttc gtcgagtcgg atggaagata ttgttgaaga ataagccctc
    11641 aatatgatag aaaccgttta caaataactt taaaaatggt ataatttaat taaaccggtt
    11701 tacttagttg ctataaatct ctaatttgag atttagttcc tattgatttt acaatatgtt
    11761 tattggagtg tatacatgca aacaaaaaca aagaagctca ttgtgagttt gtcttcactt
    11821 gttttatcag gatttttatt aaaccattat atgacagttg gagcggaaga aacgactacg
    11881 aataccattc agcaaagcca gaaggaagtt cagtatcagc aaagggatac aaaaaattta
    11941 gttgaaaatg gtgattttgg tcagacggag gacggaagca gtccgtggac aggaagcaaa
    12001 gctcaggggt ggtcagcttg ggtagaccag aagaatagtt ctgcagatgc ctcaactcga
    12061 gtcattgagg ctaaggatgg ggctatcact atctcaagcc ctgagaaatt aagggcagcg
    12121 gttcaccgta tggtttctat tgaagctaag aaaaagtata aactgcgttt caagattaaa
    12181 acagatcata aagtcgggat tgccaaagtt cgtatcattg aggaaagtga taaggacaag
    12241 cgattgtgga attctgcaac gacgtcagga acaaaggact ggcagaccat tgaagcagac
    12301 tatagcccga ctttagatgt tgataaaatc aagctggagt tattctatga aacaggaact
    12361 gggactgttt cctttaagga tattgagctg gtagaggtag cagaccagcc ttctgaggat
    12421 tctcaaacag ataaacagct tgaggaaaag attgatttac caattggaaa aaaacatgtt
    12481 ttttctcttg cggactatac ttataaggta gaaaatcctg acgttgcttc agtcaaaaat
    12541 ggaattttag aacctcttaa ggaagggaca accaatgtca ttgtcagtaa agatggcaag
    12601 gaagtgaaaa agattccttt gaagattcta gcctctgtta aggatacata cacagaccgt
    12661 ttggatgact ggaatggcat catcgctgga aatcaatact atgattctaa aaatgaacag
    12721 atggccaaat taaaccagga attggaagga aaggtagctg atagcctatc cagtatttca
    12781 agtcaggcgg accgcaccta tttgtgggaa aaattttcaa attataaaac gtctgcaaat
    12841 ctgactgcca cttatcggaa attggaggag atggccaagc aagtgaccaa tccttcttct
    12901 cgttattatc aagatgaaac tgtcgttcga acagtcaggg attccatgga atggatgcat
    12961 aaacatgtct acaatagtga aaagagcatt gttgggaact ggtgggatta tgaaatcggt
    13021 acacctcgtg ccatcaacaa taccttgtct ctgatgaaag aatacttctc tgatgaggaa
    13081 attaaaaaat atacagatgt gattgaaaaa tttgtaccag atcccgaaca tttccgaaag
    13141 acgactgata acccattcaa ggctctaggt ggaaacttag ttgatatggg aagggtaaaa
    13201 gtaatagctg gtttactgcg taaggatgat caagaaattt cttctaccat tcgctcgatt
    13261 gagcaagtgt tcaagttggt agaccaaggt gaaggttttt atcaagatgg atcctatatc
    13321 gaccacacca atgttgccta tacgggtgct tatgggaatg ttttgattga tggcctgtct
    13381 caactgttgc cagtcattca aaagaccaag aatccaatcg ataaagataa aatgcaaacc
    13441 atgtaccact ggattgataa atcgtttgct cctttgctgg tgaatggaga gctgatggat
    13501 atgagtcgtg gacgctcgat cagtcgtgca aatagcgagg ggcacgtggc cgcagtagaa
    13561 gtactaagag ggattcaccg aatagcggat atgtctgaag gagaaaccaa acaacgtttg
    13621 cagagtcttg tgaagaccat tgttcaatcg gatagttatt atgatgtctt taagaatttg
    13681 aagacttata aggatatcag tttgatgcaa tccttgttaa gtgatgcagg agtcgcaagt
    13741 gttccaagac caagttacct atctgccttt aacaagatgg ataaaacagc catgtacaat
    13801 gcagagaaag ggtttggatt tggcttgtca ctcttttcca gtcgtacctt gaattacgaa
    13861 cacatgaaca aggaaaataa acgtggttgg tatacgagtg atgggatgtt ctatctttac
    13921 aatggcgatt tgagtcacta tagcgatggc tactggccaa cagttaatcc atataagatg
    13981 cctggtacaa cagagacgga tgctaagaga gcggatagcg atacaggtaa agttctaccg
    14041 tctgctttcg ttggaacgag caaactagat gatgccaatg cgacagcaac catggatttc
    14101 accaactgga atcaaacatt gactgctcat aagagctggt ttatgctgaa ggataagatc
    14161 gcctttttag gaagcaatat ccaaaacact tcaacagata ctgctgcaac tacaattgac
    14221 cagagaaaac tggaatcaag taatccatat aaagtctatg tcaatgataa agaagcctcc
    14281 cttacagaac aagaaaagga ttatcctgaa acccaaagtg tctttttaga atcgtccgat
    14341 tcgaaaaaga atattggtta ctttttcttt aagaagagtt caatcagtgt gagtaaggct
    14401 ttgcaaaagg gagcctggaa ggatatcaat gaaggacagt cagacaagga agttgaaaat
    14461 gaatttctta cgattagtca ggttcataag caaaatggag attcttatgg ctatatgctc
    14521 atccctaacg tgggtcgtgc caccttcaat caaatgataa aagagttaga aagtagcctc
    14581 atcgacaata acgaaaccct tcagtctgtt tatgatgcca aacaaggagt ttggggcatt
    14641 gtgaaatatg atgattctgt ctctgctatt tccaaccaat tccaagtttt gaaacgtgga
    14701 gtctatacca ttcgaaaaga aggggatgaa tataagattg cctactataa tcctgaaacc
    14761 caggaatcag ctccagatca ggaagtcttt aaaaagctag agcaagcagc tcagccacaa
    14821 gtacagaatt caaaagaaaa ggaaaaatct gaagaggaaa agaaccattc ggatcaaaag
    14881 aatctccctc agacaggaga aggtcagtca atcttggcaa gtctagggtt cttgctactt
    14941 ggggcgtttt atttattccg tagaggaaag aacaactaat ttgttcatca tctagatgaa
    15001 ttacatgaaa ctgtggaaaa tagaaaaaat ccgaagaagg ccaaatatct tcggattttt
    15061 cttttaaaaa aggataagtt gatacttatc cttttttact tcattatgtg actatagcgt
    15121 tttgaaacta gaataggacg tcataactgc taaaagattt ctataaattc atttgatttt
    15181 cctaatcaat ttgttcgtat cctatttcac tccactatat tagtccgtct cgctccgtga
    15241 ggtgcgagac aaaacaacca cccgctatgc gggtgcgcgt cgaaggttat accaaaaaaa
    15301 ctccaaacac gatacaataa aggtgttcac tccacttgta aagcgaaggg agaaaaaata
    15361 tggcacaaaa gactcatagt ttatcataca caaagtggat gtgttctatc atattgtgtt
    15421 cacccctaag tatagacgaa aagtcatcta taatcaatat agaagtagtt tgggcgaaat
    15481 atttcatcgc ttgtgtagtt ataaaggtgt tgaaatgatc gagggtcact taatgccaga
    15541 ccatgtacac atgttagtca gtattccact aaggctaagt gtttcaagtt ttatggggta
    15601 tttaaaaggc aaaagtgcac tcatgatgtt tgacaaacac gccaatctca agtacaagtt
    15661 tgggaatcgg catttctggg cggaaggtta ttttgtaagt acagtagggc ttaatgaagc
    15721 cacaattaag aaatatagtc aagattaaag aaattatcca gtggatgatt tcttcacgag
    15781 tatgaaaatt tgagaactag taaagtatga tatatagtaa aatgaaataa gaacaggaca
    15841 aaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagcaga ggtgtactat
    15901 tccagtttca atctactata gcactagata aattgagtgt aaaagaatat gaggatccct
    15961 ttagggatag tggtaagtaa taccaaagtc tcttaaagag gcaagtgacg agtcaagagc
    16021 aataaggctt gaacaacgtg aaagccagcg tctttaggcg ctggctgatg atttgggctt
    16081 atagctctga gataaaccac ccgttagacg ggtagttatg attttatctg agtgtaatat
    16141 actgttgggc aatctcgctg atgcggtcaa agttgccttg ggaagcgagt ttattgagtt
    16201 cgccaccaat tccaacggca tctgcaccag cagcgaacca ttgagggatg ttgtttaggc
    16261 cgactcctcc ggttaccatt acggaaactt gtgggatcgg tgccttgact gcagagatat
    16321 atgctggact gagagtacta cctgggaaga gtttgatgat ttcactaccg gcttcaagtg
    16381 cagtcgtgat ctctgtgagg gtaatacagc ctggaatgta cggtgtgctg tagagattgc
    16441 acattttcgc agtttcagca tggaaagatg gagaaacaac gtaatttgct ccagctagaa
    16501 tggcatctct agcagttacg gcatcaagca cagtacctgc accgatacaa acactctgat
    16561 cgtcctgata caagtctaca agttccttga tgatttgtcc tgcatactga ttggtatagg
    16621 cgatttcaat agctttgata ccgcccttga tacaagcaat cgaggcttgt agtccttctt
    16681 cctttgtatt tcctcgaatg acagcgacaa ttttctgttt ttttagttca ataatcgtat
    16741 ctgatttggt catgtaattc tcctaacgaa tgatatcttg tgcatttgcc agtaaatttt
    16801 caatactagt tgcggaagtg gagagatggt ctcctggaag agtgcatttg agagttgcgc
    16861 tcgcaactgc aaagtcaatg gtagttttta gggaggaatg atggagtagt tggtaaaggg
    16921 caccagatat aaaggcatcc ccgctaccaa ttcgttgata gactgcagtt tttagttgga
    16981 cagactcttc aaatcgttct tccagagcat aggcttgata gacatttttg tcttgctcat
    17041 cactagatcg gagggtatgg aaaatggcct tgaaaccata ggcttctttt aaaagtcgca
    17101 tgcgattttc cacctcttct aggctagcac tgtctcttgg aaacatctct agattttggt
    17161 catcaatcat gagaggatca ataccgaagc aatagtcagt aaaacgtgca aacttagaaa
    17221 attcatactt ggcttctagg actgaaatca tctttgttct cagattgaga tctattgaaa
    17281 cgacaattcc tcggcgcttg gcttcttcca agagtaggag aaggatcgca cggacctctt
    17341 gaccgatagc tatggtgatt ccactaaaat gaaaatggct aatcccctga aagagagaat
    17401 ccatatctag catgtttggc cgaatctggc tgatactcgt atgcttacga tcgtagaaaa
    17461 cttcactttg acgacaacca aagccgttct ccaaatagta gaggccgatt cgatcgccaa
    17521 gccgacagat tgaactggta tcgatttggt gctgtttcaa gaatgtgaga aaacgatctc
    17581 caatctcgtt ggcagggagt gcggtaaaga ctttcgttga gatacccagg gcttgcaaat
    17641 tacaagcgat gttaatttct gatccgccaa aataagtcga actggcaaca tgatcgccga
    17701 tactggtggc atctaatggt gagattcgaa ttaatggttc gccaaacagt aatattttcg
    17761 tcatccatta gttcctttct ggtttagaat agctttactt ggctaatact tctttcaaat
    17821 aagcagcgac ttcatcatct tgacagtttt caaagaagta ttcttggaag tatttgccag
    17881 agatggtgtc tttgaggaag tcttggtcga ttgttttaag gatggtcatc aaatcattgt
    17941 gggtgatttg tttcacctcg tttaagatac gagcgttgcg ttgttcaggg attacacgtt
    18001 ctcttgggta gccaccgccc atttcttcag caaataagcg ttcaaacatc aatttgaggg
    18061 tcagttctgc cccccagcca aatcctttgg cataagggat agacaaggcg ttaccaccat
    18121 tgatttgaga ataaaggtaa gcgtcagttg ggtccactgc tagaccacag ataacaccag
    18181 ggaagctgtt taaggcaagc atagccccta cacccgtacc acagccggta acaacaaagt
    18241 caactgcctt tgtatttaaa aggatggcag ccattagtcc gttctgcaca taagttaatt
    18301 gactttctcc ttcttctcca cgcataccat agttaaataa ttggtagtct tttttatctg
    18361 tcgcttcttt tagactatcg taaataatgt gattcttgct agcttgacta ttttcattga
    18421 ttaatgcgat tttcataaga tcttctttct atttttactc aggttgtttt ccgatgtagg
    18481 ctaagatacc gccatctaca tataggatgt ggccattgac aaaattgctg gcatcactag
    18541 cgagaaagac agcagggccc atcaaatctt caggatttcc ccaacgtgca gcaggtgttt
    18601 ttgcaatgat gaactggtca aatgggtggc gagaaccatc ttcttgcaac tcacgaagag
    18661 gtgctgtttg aggagtggca atataacccg gtccaattcc gttacattgg atattggctc
    18721 caccgtattc agacgcaatg ttgcgggtca acattttcaa gcccccttta gcagcagcat
    18781 aagcgctaac tgtttcacgt cccagttcgc tcatcatcga acaaatattg ataatctttc
    18841 catgcccttt ctttatcata gaaggaataa ctgcctttga aacgataaat ggtgcgttta
    18901 agtcaatatc gatgacctta cggaaatcag cggcgctcat ttcgcacatt ggaactcggc
    18961 ggataatacc agcgttatta acgaggatgt caatgacacc aacctcttgt tcgatttgct
    19021 tgaccatggc ttggataccg tcctcgtctg tcacgtcaca gacatatcca tgggcttgga
    19081 tgccaacttc acgataagct tcaatccctt tattgaccag atcttgattg atatcgttaa
    19141 agacaatagt agcgccggct tcagcgtagg atttggcaat agcaaatcca attccataag
    19201 aagcgccggt gatgagagca atttttcctt ttaaagaaaa ctgctcaatt gagaatgatg
    19261 tatttgtcat ttgatacttc ctttcaaatt tgttaagact tctctataac caaattatat
    19321 tctagtaaac cggttttgtc aataaataaa tatttttatt tataaaaaga tttgttttcc
    19381 taaaaaaacg gaagattttg aaatttctgt ctattaaaat ggttaaaaag ataatgaaag
    19441 cgctaatatt ttttaaaaaa aactattgac aagataaaaa taaaggatta caatggggga
    19501 tataaagtaa accggtaaac ctaaacaaga aaggagaaaa gatgaaaatt gtacttgtag
    19561 ggcatggaca ttttgctaca gggatttata gttctttaca attgattgca ggcaatcaag
    19621 aaaatgtgga ggcgattgac tttgtggaag gaatgtcagc agatgaactc aagcaaaaaa
    19681 tcttacttgc aatttcaaat gaagaagaag ttttaatcct aagtgatctc ttgggaggat
    19741 cgccattcaa ggtttcttct accataatgg gagaaaatcc agccaagaca atgaatgttc
    19801 tctcgggttt gaacttagcc atgttaatgg aagcagtctt tgctagaatg gctcatagct
    19861 ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg cggagttgta aatggtaaag
    19921 aattgttttc aacggatgca gaggaagagg aagaagattt cgaattgggt atttaaaggg
    19981 taaaagaatg ataaaaaagg ttacgattga aaaaataaaa tcgcctgagc gcttcttaga
    20041 agtaccactt ctgacgaaag aagaagtcgg ccaggcaatc gataaggtta ttcggcagtt
    20101 agaactcaac cttgactatt tcaaggaaga tttcccgacg ccagctacct ttgataatgt
    20161 ctatccaatc atggataaca cggaatggac caatggtttc tggacaggag aactgtggtt
    20221 ggcttatgaa tacagtcaac aggatgcatt taaaaacatc gctcataaaa atgttctttc
    20281 tttcctggat cgtgtcaata agagagtaga attggatcac catgatctcg gcttcttgta
    20341 cacaccgtct tgtatggctg aatataagat aaatggagat ggagaggcta gagaagcaac
    20401 cttgaaagct gcagataagt tgattgaacg ctatcaagaa aaaggtggtt ttattcaagc
    20461 ttggggagac ttgggcaaga aagagcatta ccgtttgatt atcgactgct tgctcaatat
    20521 ccaactctta ttctttgctt atcaagaaac aggcgatcaa aaatactatg atattgcaga
    20581 aagtcatttc tatgcttcag ctaataatgt aatccgtgat gacgcttcgt ccttccacac
    20641 cttctatttt gatcctgaga caggtcaacc ctttaaaggt gtaacgagac aagggtatag
    20701 tgatgattca tgctgggcac gtggtcagtc atggggagtt tatggtattc ctttgactta
    20761 tcgtcactta aaagacgagt cctgctttga cttgtttaag ggtgtgacca attatttctt
    20821 gaatcgtctg ccaaaagatc atgtgtccta ttgggatttg atttttaatg atggtagtga
    20881 tcaatcacga gattcttcag caacagctat cgccgtctgt gggattcatg aaatgctaaa
    20941 acatcttcca gaggtggatg ctgacaaaga tatttataaa catgctatgc atgccatgct
    21001 tcgttccttg atcgaacatt atgcaaatga tcaatttacc cctggtggga caagtctcct
    21061 ccacggtgtg tactcatggc attcaggtaa aggagtggat gaaggcaata tctggggtga
    21121 ctactattac ctagaagccc ttatccgttt ctacaaagac tggaacctat attggtagga
    21181 ggagaaatat gacaatgcca aatattatta tgacccgtat cgatgaacgg ttgattcatg
    21241 gacaaggaca actttgggta aaatacctag gttgtaatac ggtcattgtt gccaatgacg
    21301 aagtaagcac ggacaagatg caacaaactc tgatgaaaac agttgtgcca gactcagttg
    21361 ccatgcgttt cttccctttg caaaaggtga ttgatatcat tcacaaggct aatcctgctc
    21421 aaacgatctt tatcgttgta aaggatgtaa aggacgcttt aaccttggta gaaggtggtg
    21481 tccctatcaa agaaatcaat attgggaaca ttcacaatgc ccctggtaaa gagcaagtga
    21541 cacgctccat cttcctgggt gaagaggaca aggcagccct caaggaatta agccaaactc
    21601 atcaagtaac atttaatacg aaaacaactc caacaggaaa tgatggagct gttcaagtca
    21661 acattatgga ctatatttaa aagaggagat cgttatgtcg attaatgtat ttcaagcgat
    21721 tttaattgga ttatggacag ctttctgttt tagtggaatg ctgttaggaa tttacaccaa
    21781 tagatgtatt gttctgtcat ttggtgtcg
//
LOCUS       DAVLHB010000034        21710 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLHB010000034 DAVLHB010000000
VERSION     DAVLHB010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21710
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.034"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(46..633)
                     /locus_tag="VXE36_001432"
     CDS             complement(46..633)
                     /locus_tag="VXE36_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0779724.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            875..1546
                     /gene="sdaAB"
                     /locus_tag="VXE36_001433"
     CDS             875..1546
                     /gene="sdaAB"
                     /locus_tag="VXE36_001433"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0779725.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            1555..2427
                     /gene="sdaAA"
                     /locus_tag="VXE36_001434"
     CDS             1555..2427
                     /gene="sdaAA"
                     /locus_tag="VXE36_001434"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0779726.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            2449..3081
                     /locus_tag="VXE36_001435"
     CDS             2449..3081
                     /locus_tag="VXE36_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0779727.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            3107..3205
                     /locus_tag="VXE36_001436"
                     /pseudo
     CDS             3107..3205
                     /locus_tag="VXE36_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3567..5417)
                     /locus_tag="VXE36_001437"
     CDS             complement(3567..5417)
                     /locus_tag="VXE36_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0779728.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFHTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5459..6616)
                     /locus_tag="VXE36_001438"
     CDS             complement(5459..6616)
                     /locus_tag="VXE36_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0779729.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLYQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            6674..7840
                     /locus_tag="VXE36_001439"
     CDS             6674..7840
                     /locus_tag="VXE36_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0779730.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            7979..8305
                     /locus_tag="VXE36_001440"
     CDS             7979..8305
                     /locus_tag="VXE36_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0779731.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            8292..8885
                     /locus_tag="VXE36_001441"
     CDS             8292..8885
                     /locus_tag="VXE36_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0779732.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            8878..9789
                     /locus_tag="VXE36_001442"
     CDS             8878..9789
                     /locus_tag="VXE36_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0779733.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9852..10916
                     /locus_tag="VXE36_001443"
     CDS             9852..10916
                     /locus_tag="VXE36_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779734.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11094..11954)
                     /locus_tag="VXE36_001444"
     CDS             complement(11094..11954)
                     /locus_tag="VXE36_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0779735.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEMQPILD
                     KDFKTLAQEK"
     gene            complement(12229..13215)
                     /locus_tag="VXE36_001445"
     CDS             complement(12229..13215)
                     /locus_tag="VXE36_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0779736.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13487..14962)
                     /locus_tag="VXE36_001446"
     CDS             complement(13487..14962)
                     /locus_tag="VXE36_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0779737.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(15220..16143)
                     /locus_tag="VXE36_001447"
     CDS             complement(15220..16143)
                     /locus_tag="VXE36_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0779738.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(16157..17086)
                     /locus_tag="VXE36_001448"
     CDS             complement(16157..17086)
                     /locus_tag="VXE36_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0779739.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(17405..17626)
                     /locus_tag="VXE36_001449"
     CDS             complement(17405..17626)
                     /locus_tag="VXE36_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779740.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSRKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(17580..17840)
                     /locus_tag="VXE36_001450"
     CDS             complement(17580..17840)
                     /locus_tag="VXE36_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779741.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(18267..18422)
                     /locus_tag="VXE36_001451"
                     /pseudo
     CDS             complement(18267..18422)
                     /locus_tag="VXE36_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(18607..19218)
                     /gene="rpsD"
                     /locus_tag="VXE36_001452"
     CDS             complement(18607..19218)
                     /gene="rpsD"
                     /locus_tag="VXE36_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0779742.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(19413..20465)
                     /locus_tag="VXE36_001453"
     CDS             complement(19413..20465)
                     /locus_tag="VXE36_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0779743.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(20462..21160)
                     /locus_tag="VXE36_001454"
     CDS             complement(20462..21160)
                     /locus_tag="VXE36_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0779744.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(21327..>21710)
                     /locus_tag="VXE36_001455"
     CDS             complement(21327..>21710)
                     /locus_tag="VXE36_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0779745.1"
                     /translation="GKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMN
                     HNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMA
                     SIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT         6378 a         4688 c         4102 g         6542 t
ORIGIN      
        1 cgagggattt cctcgactct ttacatatta tttgttcgtt agttcttaat accagccatt
       61 gttaagccag aagtttttag cagctgtcca tgaaccgtaa cgtcctgcaa cgtaggcatc
      121 tgctacacgt tcttggtttt cagctgagta gtcaccgttc aggtatgaat ctgttaattg
      181 gtaacgtccg atataacgtc catttgtagc tgtatagcta ccacctgatt ctttttgagc
      241 gatccattct ttggcttctg cttcagatcc gcttacagtt gaaacaactg tttcacttac
      301 tactggagtt tctgccactg gagctgaaac agtttcatct tgagcggctg gtgccgcata
      361 agtagctggc gctggtgttg caacaggcgc tacagggcca tcgataacca actcttgacc
      421 aacataaatc aaatgaatgt tatcaatgtg gttgttttct gccaattttt caactgttgt
      481 gttgtgagtt tcagcgattt ctgaaagtgt atcaccttct ttaacagtgt aagttgatga
      541 ttcttgagca gatacaaatg atggagcaaa tactgcaaac aaggcagcta ctcctgcaag
      601 agttgcttta atctttttag ttattgattt catattcgaa aattctcctt ctttctatag
      661 ttctatcata ccctttaaat attaccgttt cttgacactt ttatgtagaa atattacaaa
      721 attatttttt atttccctaa ataaggtgtt ttttgtcata aaagatacta tttttatgct
      781 atttgaggta ttagaaaggt tttcatccac aattaaagcc aagcccctca ttctttgata
      841 taatagagat aagaattttt ataaggggaa actgatgaaa tcacttcgtt ttcaatctgt
      901 ctttgatatc atcggaccag ttatgattgg cccatctagt agccataccg ctggtgctgt
      961 tcgtattggg aagattgtct cttccatttt tgatgatact ccgacagaag ttgaattcca
     1021 actttttaac tcatttgcca agacctatcg tggtcacgga acagacctag cccttgttgc
     1081 aggtatttta ggaatggata cagatgatcc tgaaattcca aatagtctgg aaattgccca
     1141 caagcgtggt atcaagattg tctggaccat tcagaaagac agcaatgccc ctcaccctaa
     1201 caccactaaa attactgtta aaaatgccca caagaccatc agcgtgactg gtatttctat
     1261 cggtggagga aatattcagg taaccgaact caatggtttt gccgtctctc tcaatatgaa
     1321 tacaccgact atcatcatcg ttcatcaaga tattccaggt atgattgccc ttgttacaga
     1381 ggcgctttcc cgctatggta tcaatatcgc ccagatgaat gtcactcgtg aaaaagctgg
     1441 tgaaaaagcc attatgatta tcgaagttga cagtcgcaac tgtgatgagg ctatcgaaga
     1501 aattcgaaaa atccctcatc tccacaatgt caatttcttt aaataggagg aagcatgttt
     1561 tattctatca aagaattggt cgagcaagca gatctggact ttcaaggaaa tgtcgcagaa
     1621 ctcatgatta caacagagtt tgaattgacc ggtcgcgaac gtgaagaagt cttccttctc
     1681 atggaacgca atctggaagt tatgaaagcc tctgtccaac ttggcctcaa tgaaaataaa
     1741 tctcgtagtg gcctgacagg tggagatgct gccaaattgg atcactacat cgaaaacgga
     1801 aaaactctgt cagattatac gattctctcg gctgcccgaa atgccatcgc agtcaatgaa
     1861 cacaatgcca aaatgggctt ggtctgtgcc actccaaccg ctggaagtgc tggctgtctg
     1921 ccatccgttc tcactgctgc tattgaaaaa ttagacctca gccacgagca acaattggat
     1981 ttcctctttg ctgctggtgc ctttggacta gtcatcgcaa acaatgcctc catctcaggt
     2041 gctgagggtg ggtgtcaagc tgaagttggt tcagcctctg ctatgagtgc tgccgccttg
     2101 actctggctg caggtggaac accttatcag gccagtcaag ctattgcctt tgtcattaaa
     2161 aatatgctag gcctcatctg tgaccctgtt gcaggtttgg tcgaagttcc ctgtgtcaaa
     2221 cgtaatgcca tgggagctag ctttgctttc atcgcagcag acatggcctt ggcaggtatc
     2281 gaatctaaaa tccctgtgga tgaagtgatc gatgccatgt accaagtagg agcaagcatg
     2341 ccaactgcct ttcgtgaaac agctgaaggt ggactcgcta ccacccctac tggtcgtcgc
     2401 ctccaaaaag aaattttcgg agaataagct tatcaaatag gagaaaccat gacctctatc
     2461 acagcgattt ttttcgattt ggatggaacc ctcgttgata gttctatcgg gattcacaat
     2521 gcctttacct atacctttaa agagctgggg gtgcctagcc ctgatgccaa aactattcgt
     2581 ggttttatgg gaccacctct cgaaagtagt tttgcgacct gcctgtccaa agaccaaatt
     2641 tctgaagccg tgcagatata tcgttcttac tataaggcaa aaggcatcta tgaagctcaa
     2701 ctctttcctc agattataga cttgcttgag gagttatcga gcagttatcc actctacatc
     2761 accacgacaa aggatacatc tactgctcaa gacatggcaa aaaacttgga aatccatcat
     2821 ttctttgatg gcatttatgg ttctagccct gaagcacccc ataaggcaga tgtcattcac
     2881 caagccttgc agacacatca actagcacca gaacaagcca tcatcatcgg agataccaag
     2941 tttgatatgc tgggagctcg agaaacaggt attcagaaat tggccatcac ttggggattt
     3001 ggagagcaag cagatctact aaactatcaa cctgattata tcgctcacaa acccttagaa
     3061 gttttggcgt attttcaata gcatagactg ggtaacaatt ccatttcaga agaaaatgaa
     3121 gtaatactca atgaaaatca aagagcaaac taggaaacta gctgcgggct gctcaaaaca
     3181 ctgttttaag gttgtagatg gaactgacga agtcagctca aaacactgtt ttaaggttgt
     3241 ggatggaact gacgaagtca gctcaaaaca ctgttttaag gttgtggatg gaactgacga
     3301 agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaaca
     3361 ctgttttaag gttgcagata gaactgacga agtcagctca aaacactgtt ttaaggttgc
     3421 agatagaact gacgaagtca gtaacatata catacggcaa ggcgacgttg acgtggtttg
     3481 aagagatttt cgaagagtat aagtctctac ataataaaac gcatattacc aaggttgtgt
     3541 aacttgatac tatgcgtttt tcttttttat tcaatgtggg ttgtttgatt agcaaaggcg
     3601 ataatagctt gcttcaactc atctccactg agagtgtgga actctccaat cttttgattg
     3661 atggattcta aaggcatgac attaacctta ccaacgaaaa tcttatccat aacttgatta
     3721 tcaacgagtt cggttgatac caagagttct tcgtagagtt tttcacctgg gcggattcca
     3781 acttcaacga ttggaatttc actttcagtg tggccactta gaagcaccat cttcttggcc
     3841 aagtcataaa tcttgactgg tttgcccata tcaaggataa agacttcccc atctttggca
     3901 taagcaccag catggataac cagacggcta gcttctggaa tggtcataaa gtaacgggtc
     3961 atgcggaagt ctgtcaccgt tacaggccca ccttcagcaa tctgacgttc aaagactgga
     4021 atgacactac cacggctacc aagaacattc ccaaaacgaa ctgcacagta ggttgattgg
     4081 ctacgttggt taaagccagt gacaatcaac tccgccacgc gcttggttgc tcccataaca
     4141 tttggtggat taactgcctt atctgtcgaa atcataacca tcttagacac tttagcttca
     4201 tcaacagcct tagcaacatt gtaagttcca cggatattgt ttttgaaggc ttcttttgga
     4261 ttgcgctcca tcataggaac atgcttgtgg gctgccgcat gataaacaat agcaggtttg
     4321 tactgctcaa agacttgcaa caaacgatca tagtcttgaa tgtccgcaat cacaggtaca
     4381 taatcaatcc cttggaactt acgaatcaat tcatgataaa caaggtagat tgagttttcc
     4441 ccatgaccga gcaagacaat gcgttcagga ttgaagcgac taacttgacg acagatttca
     4501 gaaccgattg aacctccagc tcctgtgact aagatggtct tacctgtcag ttctgcaccc
     4561 agacgcgatt cgtcaagacg gatttcctga cgacccaaaa ggtccgtaat atcaattttt
     4621 tggaagccag tacctgcttg gtgaaggccc tgaacaacag tttcaacctt aggcatcttg
     4681 taacatttga cacccagctt attacacatc tgcaagatac gctcatattc tgacggatcc
     4741 agcgacggaa tcgcaacgat gacacgctcg atttgatggc gtttggctaa ttcaggcaga
     4801 ttgtcataag agcccaaaac aggaatacca ccaagttttt gacccttttt cttagaatcc
     4861 ttatccaaaa taccgaccag ttctaattca ctggttggat gttggtaact atccataaaa
     4921 agagccccac catcaccggc accaatcaag aaggtccgac ggtgttctcc atcaccacta
     4981 ccttttttgc gtctggagta gattaactgc caagtaatcc gtggcaataa aatcaagaag
     5041 gtactcaaca agataaagag aatgataaaa cggatggaga agagtggcaa gaaggcataa
     5101 cagatactat atgacaagac actgctagca gtcacaccaa aaaagatttt catgaaatcc
     5161 gtaatcttgc tgtaacgact aatgctcgcg ttcaaccccc aaaaaccaat catcaattga
     5221 tagaacagga aggccaaact cgtatagata atgtagtcaa caggtgctgg attaatcagc
     5281 ccataaaata aaatataaga tacaattatg gaaaccacca tactgaaaat atcaaatatt
     5341 ccccagaaaa cctgcttttg ttgtttattt aaaatttcca ccagatcaat cacataatct
     5401 gttagttttt tattcataga aatctactcc tccttaaaag agttttacta tattgttatt
     5461 atagcatatt tttatttatt tggcttattt tatccaaata aattattgtt ctcttgtact
     5521 ccttcttcca tttaaatcct ctaattaaac ctacaatcgt cccaaagcca taagcaaagt
     5581 gaatggaaaa taaaagaaag ggcatcacaa ttagaaatcc atttttatgt tttaataaag
     5641 tcagcaaagt gagtagtgac aaaagtagaa aataggcacc taatagtaaa gttatgaata
     5701 cgaatgtgat cggtaacaat gctagactaa acacaagact caaaacaaat aaacaaggaa
     5761 catagtgaaa taatgataaa cacttaaact gaacatgact tgtcaagcca atccacaaac
     5821 catttgaata cttttgatac agcattttct tgaatgttgg tcgaatatac tgataagata
     5881 gaatacttgg gctatagcga attttataac catgttctcg aattctataa tgaatatcat
     5941 tatcttcagt tcggccaagt tgctcattta ctaaaccaac cttctggaaa acctctcgtt
     6001 tatacatccc atgaaaaata gaagaaacat atctatcttc ggaactattt cgataattgg
     6061 caatgctact gccaaacata ttttcctcaa caagatgcaa ggtctctgcc cattttcctt
     6121 ttccttcgac aatcgtcggt ctaggccccc cacagacaaa ttcaccttgt tgaataatag
     6181 ccacattgtt cattacaaaa gtctcagtaa cttttgaatg agcatcaatt tttaaaataa
     6241 ggtcccctac agaatgttta actcccaggt taaaaccact agcttgattt ttcttaggat
     6301 tgttatacaa tctaattgag ttaaactctg tatcttcctt tataaattgc tgaatgatag
     6361 ctgtggtccc atctgtggac atagcattta taaatagaat ttcaatattc tctttaggat
     6421 aagtttgatt ttttaagtct tcaattagac caggcagata tttttcttca ttgtatgcac
     6481 tgattacaat ggatacgaga agactttcaa cattttgagt cactactact ctcctgaatt
     6541 tttccttcca ccattctatc ataattttca agactttccc atttttatct tgaaagccag
     6601 aaaccttact tgacattata gtgaaaaagc cttaaaataa gctgttatta aaatcagcta
     6661 gaagaggtat tatatgaaaa agcaatcact cttttttgtt ccaggtatta tcctgattgg
     6721 tgtttccttg cgaactcctt tcactgtttt acccattatt ttgggaaata tttcgcaagg
     6781 tctggaggta gaagttagtt cgcttggtgt cttgaccagc ctgcctctcc ttatgtttac
     6841 cctcttttca ccattttcta cccaactggc tcagaaaatc ggcttggagc atctcttcac
     6901 ctacagcctc ttcttcttga ccatcggctc actcattcga ctaatcaatc tgcccctgct
     6961 ctatctagga accttgatgg ttggggcaag tgtcgcagtc atcaatgtcc tgcttcctag
     7021 tcttatccaa gccaatcaac caaagaaaat tggttttctg accaccttat atgtaacgtc
     7081 tatggggatt gcaacggctc tggcttccta tctagctgtg cccattacac aagccagttc
     7141 ttggaaagga cttatcctcc tcctcacgtt actctgtcta gcaacttttt tggtctggct
     7201 cccaaatcac cgctataatc atagactagc tccacaaacc aaacaaaaaa gtcaaataaa
     7261 ggtcatgcgt aataaacagg tttgggcaat tattatcttt tcaggttttc aatccttgat
     7321 cttttacacc gccatgacct ggttacctac catgtctatc catgcaggtc tatccagtca
     7381 cgaagctggc ttgctgactt ctatcttatc tctgattagc attccttttt caatgaccat
     7441 cccaagcctg acaaccagtt tatctactcg caaccgtcag ctcatgctca ctctggtttc
     7501 actagctggt gtggtcggca tttccatgct ctttttccca atcaataatt tcatttactg
     7561 gcttgccatc catctcctca tcggaaccgc aaccagcgcc ctcttccctt atctcatggt
     7621 caacttttca ctcaagacaa gcgcccctga aaagacagcc caattgtccg gcctatctca
     7681 aacaggaggc tatatcctag cagcctttgg gccaaccctc tttggttaca gttttgacct
     7741 attccactct tgggtaccag ctgtagctgc cctcttgctc atcgatatcc tgatgactgt
     7801 ggccctcttt acagtggaca gagcggataa gatcctttaa acttctagtt ttagctagaa
     7861 gttttttata tataaaaatt ttacacattt ctcttgacag ggctttcttt tagatgtaca
     7921 atgtatgtgt agaaaaatta tatataaaaa tcttacacat tagaaaagga ggtttcccat
     7981 gtactttcca acatcctctg ccttgattga atttctcatc ttggctgtac tggagcaggg
     8041 tgattcttat ggttatgaga ttagccaaac cattaagctg atcgctaata tcaaagaatc
     8101 cacactctat cccattctca aaaaattgga aggcaatagc tttctgacaa cctattctag
     8161 agagttccaa ggtcgcatgc gcaaatacta ctccttgaca aacggtggta tagagcagct
     8221 cttgacccta aaagatgaat ggacactcta tacagacacc atcaatggca tcatagaagg
     8281 gagtatccgc catgacaaga actgaatacc tgactcagct agaactctat ctcaagaaac
     8341 tacctgaagc tgaccgtatc gaagccatgg actatttcag agagctcttt gacgatgctg
     8401 gagtcgaagg agaagaagaa ctcatcgcta gtttgggaac tcccaaagaa gtggcccacg
     8461 aagttctatc caatcttctc gataaaaaaa tcaatgaagc acccgctcaa aaaaataacc
     8521 gacaaatttt acatatcgcc ttgttagccc tccttgcagc acctatcggc attcctctgg
     8581 gaatcgccat cctcgtgacc ctgttcgcaa tccttgtagc cgctttgact gtcattctgg
     8641 ctttctttgc agtttccata ctgggtatca tcggcggatt cctattttta gttgaaagtt
     8701 tcactgtcct cgcccaagcc aaatcagcct ttatcttgat ttttggttct ggtttactgg
     8761 ctatcggtgc ttcttcgcta gttttacttg gcatttccta tgtagctcgc ttcttcggtc
     8821 tactcattgt tcgtctggta caatttgttc ttaaaaaagg aaagagaggt aatcagcatg
     8881 cgtaaatgga caaaaggatt tctcatcttt ggtgtggtga ctaccgttat cggctttatt
     8941 ctgctttttg taggtatcca atctgacggg attaagagcc tactttccat gtccaaagaa
     9001 cctgtctatg atagccgtac ggaaaagcta acctttggca aggaagtcga aaacctagaa
     9061 attactctcc accaacacac gctcaccatc acagactctt tcgatgatca aatccacatt
     9121 tcttaccatc catctctttc tgctcaccat gatcttatca ccaatcagaa cgatagaact
     9181 ctgagtctca ctgataagaa actgtctgaa actccgtttc tctcttctgg aattggtggg
     9241 attcttcata tcgcaagtag ctactctagt cgttttgaag aagttattct ccgactacca
     9301 aaagggagaa ctctaaaagg gatcaacatc tcagccaatc gcggacaaac caccatcata
     9361 aatgctagcc ttgaaaatgc gaccctcaat acaaacagct atatcctccg aattgaagga
     9421 agtcgtatca aaaacagtaa actcacaacg cccaatatcg ttaatatctt tgatacagtt
     9481 cttacagata gtcagctaga gtcaacagag aatcacttcc acgctgaaaa tatccaagtc
     9541 catggtaagg ttgaactgac tgccaaagat tatctcagaa tcatcctaga ccagaaagaa
     9601 agccaacgaa ttaactggga catctcaagc aactatggtt ctatcttcca attcacaaga
     9661 gaaaagcctg aatcaagagg tacggaatta agcaaccctt acaaaactga aaaaaccgat
     9721 gtcaaggatc aactcattgc gagatctgat gataatattg atctaatatc cacaccaagc
     9781 agacgttgac aaaaacgctt acatctgcta ctatggaagc atatttatct aactaaaaag
     9841 gaggttctac catgaaacaa gaatggtttg aaagtaatga ttttgtaaaa acaacaagca
     9901 agaacaagcc tgaagagcaa gctcaagagg ttgcagacaa ggctgaagaa acgatagccg
     9961 atctcgatac accaattgga aaaaatactc aagtagagga ggaagtctct caagctgaag
    10021 tcgaactgga aagccagcaa gaagagaaaa ttgaaactcc tgaaggcggt gaagcgagaa
    10081 cagaaataga agaaaagaag gcatctaatt ctactgaaga agagccagac ctttctaaag
    10141 aaacagaaaa agtcactata gctgaagaga gccaagaagc tcttcctcag caaaaagcaa
    10201 ccacgaaaga gccacttctt atcagtaaat ctttagaaag tccttatatc cccgaccaag
    10261 ctccaaaatc tagggataaa tggaaagagc aagtgcttga tttttggtct tggctagtgg
    10321 aagcgatcaa atctcctaca agtaagttgg aaacaagtat cacacacagt tacacagcct
    10381 ttctcttgct cattctgttt tctgcatctt cctttttctt tagtatctat cacatcaaac
    10441 atgcttacta tggacatata gcaagcatta acagtcgctt ccctgagcag ctagctcctt
    10501 taactctttt ttctatcatc tctatcctag tagcgacaac actcttcttc ttttcattcc
    10561 tcttgggtag tttcgttgtg agacgattta tccaccagga aaaggactgg acgctagaca
    10621 aggttctcca acaatatagt caactcttgg caattccaat cttcctcact gctattgcta
    10681 gtttctttgc tttctttgat agcctacgat ttacagccct cttgtgtgtg attagcattg
    10741 gaatcattct gcttgccagt ctccatatca ttacaagacc aagtcaagca agtgaaaccg
    10801 actccttcta tcaattattc ttgtctgtcc ttgtgaacgg agttattatc ctcctcttct
    10861 ttgtagctga agtggcactg attggagatt atcttcgtat cttggccttt ctttaaactt
    10921 catactcttc gaaaatcaaa ttcaaaccac gtcagcttcg ccttaccgta ctcaagtaca
    10981 gcctgcggct agcttcctag tttgctcttt gattttcatt gagtagcaat cctgtcatcc
    11041 ttggcaggat tttttctatg tcaaaaaagc aagtcgattg acctgcttct gctttacttt
    11101 tcttgtgcta atgttttaaa atctttgtct aatatgggtt gcatttctat ttgattggcg
    11161 tctagttggt ggtaaaaaga tgggggtaat acctctaaga attttgcata gtccaagcgg
    11221 gcaatggctt catagtcttc tggtttagag ccgtctcctg tgatttgaac caagtcaatc
    11281 tcccactgga cttccttatc caccaattgc tcaatatagg ctgcaggaac aaacggttct
    11341 ctcggtaaaa ctgtcttgac tccttgagct agatggtaaa cgccatgcac ttttccttct
    11401 ccatcctgat agaaggaaac tctcgcaaag taggcatctg tctcttgaac cgcacgcaca
    11461 cgcgcttcaa actgagccaa gccatctgcc tctaaaaagc ttttcaagtt ctcacgacta
    11521 aagaaaatag gattaaaaat tccttggcaa atcgtaaaac gagctacagg gtctgctaga
    11581 taggcttgaa tacttgcttg gaaataagct tcaaaatcaa aaccatctag cccttcaata
    11641 tcagtccctg tataagcaag caaagcatct aaaaatgact tgataatctg ccagtctgtc
    11701 tttgttagta ggtcaggaag atcgacacgg taagcctttt gaccatcagc ataactgacc
    11761 ttaaaaagaa attgtgattg ccccactatc gcacactcaa tatactcgag acgattaaga
    11821 ggctgacgga gatagactac atcatagcta tgtgactcca aaccgtctag caaggccaag
    11881 atcgacttgg cattcaaaat ctcttgttct cctaaaatgc tctgtttatt tggaataaaa
    11941 aatgttttcg ccataactgg actcctttga aatcgtttac atacagtata ccttattttt
    12001 ctgaaagata caaaaacaaa ctttatattc ttcgaaaatc tcttcaaacc gcgtcagctt
    12061 cgccttgccg tagatatatg taactgactt cgtcagtctt atctacaacc tcaaagcagt
    12121 gctttgagca tcctgcagct agcttcctag tttgctcttt gattttcatt gagtattaga
    12181 tttttgagta caaagcatag aaaaacagcc cctgaggact gtttgatctt atacagtagc
    12241 tgcctgatcc aagctttcac cgatagcggc taggcgctca atcacttcag cttgtgtcaa
    12301 ttcatttttt gaaacatagc ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg
    12361 aaggtacttg tcttcatttt cttctgatgt caagatacga cggttacaga agggatttcc
    12421 acagttgaca taacgttcac atggtgttcc atcaaaccag tctttcccta cgatggttgg
    12481 gttgacatgg ttgacatcaa cggcaatacg ctcgtcaaag acgtacattt tcccatccca
    12541 aagctcacct tgaacttctg ggtctttacc gtaagttgcg attcctccgt gcaattggcc
    12601 gacatctttg tagccttcac ggaccatcca gcctgagaat ttctcacagc gaacgccacc
    12661 tgtacagtaa accacgacac gcttgtccat gaatttttcc ttgttatcac ggacccattg
    12721 tggtaactca cggaagttgc gaatatctgg gcgaatagcc ccacggaaat gtcctaggtc
    12781 gtactcataa tcgttacgtg tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt
    12841 gaactctttt ggagacaagt aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa
    12901 gtcgttgtct tccaaaccaa ggtggacaat ttctttcttg tagcgaacaa acatcttctt
    12961 gaaggcttgt tcattttctt cgtcaatctt gaaccagagt tcttccattc ctggaaggct
    13021 gtgaacgtag tccatgtatt tttgagttgt ttcatagtca cctgaaactg ttccgttaat
    13081 tccctcgtca gcgactagga tacggccttt aaggccgatt gatttacaga aagccaagtg
    13141 gtctgcagca aattgctctg cattttcaat tggagtataa aggtagtaaa gtaagacacg
    13201 aatatctttt gccataagat ttgttctctt ttctattctt aaattttcta aattttttat
    13261 ttatctacac tagtatacct gcttgagaaa acgaatgcaa tttatttgac tggaaattgt
    13321 agagggttct cgaaatttcc tgaatggtta aaataaggac aagagaaaac atggatatct
    13381 atatccttgt gccaaaaaaa ccactgccct ccccagacca acctgaggaa agcagtgatt
    13441 cttattttag gagttaggaa tgaatacacg aaatcaattt agctgattat tttttgtttt
    13501 tcaagaattc atcgtattgt ttttgcattt cgttcaatac tttttcgtag gcaccttcag
    13561 atttcaattt ttccatcaat tctggaatcg ctttatctgg gtctacagta ccagtgttga
    13621 tagctgtatc aaattgttgc attgtgttag caatagctga gatttcagat ttcacattgt
    13681 cagtattgaa gataaatcca agcgctggag attctttagc ttctgccaat tctttcttag
    13741 aattttcgat ttgttggtct gtaacgtttt cgttgatgta aaggatccag ttgttaccag
    13801 tgttccatcc acccatgtga gtgtttcctt tgtagccatc aagaacgcga acacggtttt
    13861 ctttaccttc aattttttcc cagttcttgc cttctggacc gtaaacaaga ccgttcaaga
    13921 gttctggatt cgtattcaag aggttcaaga tttccattga tttttctttg ttcttagagt
    13981 tgtttgagat gacaaagtta gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa
    14041 ttggtttgat ttggatatct ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag
    14101 ctggtcctac tgtttcttca cgaacgaacc aagtatcttg ttgaaggtca aaggaagtat
    14161 cgcttgttgc gacgtctttt ggaatgtagc cagcttcata gaatttgtga agagtcttca
    14221 agtgttcttt gaaacgaggc acttcgtaac ggtttacaac tttagtagta tcgccttcaa
    14281 ggtcgataac gaatggaaga ccgtttgcta ctgggtagtc aaagttatca gatgggatga
    14341 aaactttacc aatagcaaat ggtactacgt ctggagcttt ttctttgatt tgtttcaaga
    14401 ctggctcaag agtttcgtaa gaagtaacac ctgaaatatc gataccatat ttagcaagga
    14461 gagttccgtt gaaggcaaag ttttgagatg atgcaacgtt ggctgcaact ggaacagcgt
    14521 aaatcttacc atttacagta ttacccttga tgtaagctgg gtcaagtgct ttgtaaaggt
    14581 ctttaccttc ttttttgtac aattctgtca agtcagcgta agcacctttt tgagcattta
    14641 caatatagtt atctgcaaag gcaatatcat agttttcacc agatgatgtg ataactgaca
    14701 ttttcttacc atagtcaccc cagccaaggt attggatatc caatttggca ccaacttttt
    14761 cttcgatgat tttgttggca tttgctaaca attcatccaa gttgtctggt ttgtcaccga
    14821 tttggtacat tttgataaca ggtttgtcac ctgaatcagc agcttttttg ctgttacctg
    14881 tcaaatttcc acaagcagca agacctgcag ccagagcgac tacactagca gatgcaaaag
    14941 catatttttt ccagtttttc atgacaaaaa ctcctttttt tatttttaaa cttataaaca
    15001 atgtaatgat cttatactca atgaaaatca aagagcaaac tagaaaacta gccgcaggct
    15061 gctcaaagca ctgctttgag gttgtagata agactgacga agtcagttac atatatctac
    15121 ggcaaggcga cgttgacgcg gtttgaattt gattttcgaa gagtattaac ttcacacaag
    15181 ggaagttggg aactgagaaa tgttatttct caataagcac tattctttca caccaccgat
    15241 agtcaaacct tttacaaagt agcgttggaa gaatggatac aaaatcgcga ttggaagggt
    15301 tgcaaccaca accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc
    15361 agtcaagccg accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata
    15421 ttgcaatgga tacaagttgt cactcttgat gtaaagaagg gcgttgaacc agtcattcca
    15481 gaaaccaaga gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca
    15541 gatttggaag aaaatccggg cctcactggc accatcgata cgagccgatt cgagaatggc
    15601 ttctggaatg gtcttcttga agaaggaacg catcaagatg atattgaatg gtgagagaag
    15661 cattggaaca atcaaggccc aaacagtgtc accaagctga agtacacggg tcaccatgat
    15721 ataacctggt accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa
    15781 tctgcgatac ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac
    15841 atttgtcaat gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt
    15901 atccttaaac tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct
    15961 atagccgtat tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa
    16021 aggtaggata caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt
    16081 cttactgaag gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc
    16141 catattctcc tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt
    16201 ttgataggat aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca
    16261 taccgatatc tgctgtctga gtcaaaccat taaaaacata tacgtccaaa acgttggtta
    16321 cattgtaaag ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga
    16381 agatatttcc gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg
    16441 ttacgttgcg aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg
    16501 ttggatcaat tcccatgatc gtcgcatagt acatgacact gctatatcca aagcctttcc
    16561 aaatacctag gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt
    16621 ctttgagacc aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg
    16681 catctgtaaa gaaactaatg ataacccaag acaagaagta agggaacaac atagaagttt
    16741 gaaaaatctt caccattctc ttagaacgga gctcgctgag gataatggca atccctacag
    16801 atacaactaa acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa
    16861 taaaggcgtc tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat
    16921 ttatgatact atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt
    16981 tcccaaatac tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca
    17041 agagaaagat ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt
    17101 ttattttgat atccatctaa aaattctttt ttagactttt gataacgatt acattattag
    17161 tatactccta tttgcaggtt aggttaaact cctaattata gaaaaaactc cacaaattat
    17221 gtagcagatt taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt
    17281 ttatctctat tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata
    17341 ctgaaaaatc tccagactag ggaactcaga gatagttcct aatctggaga tttttaatat
    17401 gttattaggc gtttgctttc aacttagcaa taacctcttt aagattatca atcacctctg
    17461 cttcagtatg ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt
    17521 ttcgagagtt ttcaaggaca tccttatcta ctgtttcaag gtttgagtct ttaagaagtt
    17581 tacttaattc cttggctaat ttcttgagtt tgatttgcag actcatcttc tcctgctgtt
    17641 tctttgcccg ctgtttgtcc tccatcctta gttgctgact ggctttcctt aatggactct
    17701 agggaagcaa tggcatcttt gactgtttgc aagatatcac gtaaaccttg ctctgtcaaa
    17761 ctatcatctg caagagcttt cttagcctct gccaaaacca gacgtgctga atctgtggta
    17821 ggattcgata cacctgtcaa tgatctcaaa agattttcta aggtttgagt ctgcttacta
    17881 atactagact aaaatcaaaa agcattacat aacagtgata tgaaatcaac taaagaagaa
    17941 atccaaatca tcaaaacact tttaaaagac tctcgtacag ctaaatatca taaacgcctt
    18001 caaatcgttc tatagtaaaa tgaaacaaga acaggacaaa tcgatcagga cagtcaaatc
    18061 gatttctaac aatgttttag aagtagatgt gtactattct agtttcaatc cattatattt
    18121 cgtctgatgg gcaaatctta ataaagagat tatagagctt ttatagtgat ttgaaataag
    18181 atgtgaacaa ctctatcagg aaagtcaaat taatttatag aaatatttta gcagccaagg
    18241 tgtactgtta taaattcaat acactatact tggtggttta gctctcctgt tttctctttt
    18301 agctttaacc agccataaat ggtattacgt gagatttgga aaacgtgtga tgcttctgtt
    18361 atactacctg ttcgctcaca ataagagaga acttttttac gaaaatctat tgaatatgcc
    18421 ataaaagatt ataccacatt gtgtactatt tttggttcat tttactatat cactttggac
    18481 tatatcggtc tagttatgtc tcaacgatta tagctggata ctaagagaaa tcaaaaaagc
    18541 actaagggag aacgtcccaa agtgcttaat atcaaggcct caaagcctgt cttattcaat
    18601 aaaatattac aacatcttgt tgtagaattc aacgacaagt gcttcgttga tttctgggtt
    18661 gatttcgtcg cgttctggca agcgagtcaa tgaaccttcc aacttttcag cgtcgaatga
    18721 tacgaatgct ggacgtccaa gagtagcttc tactgcttca aggattgctg gaactttcaa
    18781 tgatttttca cgaactgaga tcacttgacc tggagttacg cggtatgatg ggatatcaac
    18841 gcgtttcccg tcaacaagga tgtgaccgtg gtttacgaat tgacgagctt gacgacgagt
    18901 agtcgcgaga ccaagacggt aaacaacgtt atccaaacga cgctccaaaa gaagcataaa
    18961 gttgaaacct aggattccgc ctttgatttt tgtagcttgt acgaacaagt tacggaattg
    19021 tttttcacct acaccgtaag tgaaacgaag tttttgtttt tcagccaatt gcaaaccgta
    19081 ttctgacaat ttagaacggt tgtttgggcc gtgttgtcct ggtacgtagt tacgacgtgc
    19141 caattcttta cctgtacctg taagtgaaag gccaaggcga cgagcttgtt tccaagatgg
    19201 tcctgtataa cgtgacatat gaatgtcctc ctgatataaa taatatttcg gtggaaatag
    19261 tcacttagaa agccctgatt cgtgcagatg cccttcgcct aaacagccaa ggttacttgt
    19321 cataagacac ctgttgacga gcttcatgct ttcctgctga tatttcacac aaaatccatt
    19381 ttaccatgaa tagctggatt tgtaaagggg ttttaggctt tattttcact accagagagg
    19441 ttgagaacga gagtaaaggt acttcctaga ccgtactggc tgctgactgt gatttcccca
    19501 cccaattgat gggccaattc acgcgcaatc gcaagtccta atccatgacc acctgtcttc
    19561 atgttacgcg aagtttcgac acgataaagg cgtttgaaaa tattttccaa atcctctggg
    19621 gcaataccct gcccttcatc ggtcacactg attgaaagct ggtccttctc cagcttagcc
    19681 accacttcca gcttggttcc tggagcagaa tatttaaaag cgttatcgac cagattcacc
    19741 aagatacgag aaagcttagc ataatctccc tcaatccggg cagactctgg gattacctgc
    19801 aagtggacat ctcttctctc ctgctcaatc aaaaactgaa attcactcat gcactcaatt
    19861 aagagcttgt ccagaaaaat actgtcttta ctggtagttt ccacctgatt tctagctgtg
    19921 tttagggtca aaaaattcaa ctcctcaacc agtttattga gcctctccgt ctggcgtcca
    19981 atggttgcta gataatgagc ttgctccgac tccttgataa tcccatccaa aatcccttct
    20041 accgtcgctt ggatcgaagt gataggagtc ttaatatcat gcgacaactg agcaatcatc
    20101 aagccctttt ctcgttcgct ttcttccaag gaatcaaagc ttacctgcaa atcatgggac
    20161 atctcattaa aagtttgccc taattgctga aattctacag gaccttgaac ctccaaattt
    20221 gaaggaaaat ccttggccgc tacccgcttg gcatgctcct tgagtttgcc caacgacgta
    20281 aagactggca ataggagaaa gagactaatc ccagcaccga caaggctggc aacgatggtc
    20341 atcccaagca aaaagtaaat ctcgcctttc gcaatcagca ttttttgaac agcccaaaaa
    20401 acaaccaaaa tggttaagag ggttgaaata atatatccaa ccaaaatata actttttagt
    20461 ttcatgtttg tcctctcggt ttctctatct tatatcccaa cccccaaact gtcttaatag
    20521 tgggcgtttg gtcactacta tattttgcca gctcctgtcg aagagcatgg atatgcacat
    20581 tcaaggtatt ggtgtcatcc acgtagtctt ctttccagat cttttcatag aggtctgtct
    20641 tggagaaaac tcgctctgga ttgctagcta aaatccacag caattcaaat gatttaacag
    20701 ttaaatccag catttcttct cctatttgaa cttcatgact actatgattc atttttagat
    20761 tgccaaggga aatcagctct gtttcgcccc cacgatgaag gcggcgcaaa atattgtgga
    20821 cacgcaaaac tagctcacgt gggctaaaag gcttagcaat aaaatcatct gctcccaagc
    20881 tcaggccgta aatcttgtcc tgttcactgg tcttagcagt aataaatagg aaaggctgct
    20941 ctggtgataa gtattgaacc tcactgatta aatcataacc atccatccga ggcatcatga
    21001 catctgtgat aatcaaatca atcggttttt tcttgaacag ctctagcgct tccagtccat
    21061 catgggctac caagacctga taacctgcct gaattaagta tctctgatga atatctgtga
    21121 tttctacctc gtcgtcaacg agtaaaattg tctttcccat ctgtctctcc tttgataaaa
    21181 acagtgctat actgctttaa gtataacact atttttattg ttttacgatg attttaatct
    21241 gctattgaaa gaaagtcctg attgctgatt gagttgttaa actaatctta gtcagcccac
    21301 tatccatcat ttatttcctt agctgattag ttttcttctt ttttgttttt caaacctaga
    21361 ccaccgagta aacctgcaag cgcaagccca aggaaaccaa tacttgccat tgatgtttga
    21421 gtctcaccag tatttggtag catagcttta tcctctgaca tcatcgtatc agacatcttg
    21481 ttagcagaag cagccatgtt ttcacctgcc atcgtgttgg tagaacttgt catggtgtca
    21541 gcaggcatgc tatctgtagt acctgtagca tgattgtgat tcatcggagt cacgccagaa
    21601 ccagagttag aaggtgataa tgaaccattt gctgtgtctg atgtttcttt aacatttatc
    21661 ttaatagtga cttttttagt tgctacgatg ttgtccaagt ctggtttacc
//
LOCUS       DAVLHB010000035        21320 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLHB010000035 DAVLHB010000000
VERSION     DAVLHB010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.035"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VXE36_001456"
     CDS             complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VXE36_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0779746.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1250..1939)
                     /locus_tag="VXE36_001457"
     CDS             complement(1250..1939)
                     /locus_tag="VXE36_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0779747.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1951..2829)
                     /locus_tag="VXE36_001458"
     CDS             complement(1951..2829)
                     /locus_tag="VXE36_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0779748.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VXE36_001459"
     CDS             complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VXE36_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0779749.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3705..4727)
                     /locus_tag="VXE36_001460"
     CDS             complement(3705..4727)
                     /locus_tag="VXE36_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0779750.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4732..5439)
                     /locus_tag="VXE36_001461"
     CDS             complement(4732..5439)
                     /locus_tag="VXE36_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0779751.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5775..7262
                     /gene="tacF"
                     /locus_tag="VXE36_001462"
     CDS             5775..7262
                     /gene="tacF"
                     /locus_tag="VXE36_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0779752.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFFPFATYGVYSYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7272..8075
                     /locus_tag="VXE36_001463"
     CDS             7272..8075
                     /locus_tag="VXE36_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0779753.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     INLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8077..8886
                     /locus_tag="VXE36_001464"
     CDS             8077..8886
                     /locus_tag="VXE36_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0779754.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKS"
     gene            complement(9160..12336)
                     /gene="carB"
                     /locus_tag="VXE36_001465"
     CDS             complement(9160..12336)
                     /gene="carB"
                     /locus_tag="VXE36_001465"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0779755.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTRLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12648..13727)
                     /gene="carA"
                     /locus_tag="VXE36_001466"
     CDS             complement(12648..13727)
                     /gene="carA"
                     /locus_tag="VXE36_001466"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0779756.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13777..14700)
                     /locus_tag="VXE36_001467"
     CDS             complement(13777..14700)
                     /locus_tag="VXE36_001467"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0779757.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14719..15240)
                     /gene="pyrR"
                     /locus_tag="VXE36_001468"
     CDS             complement(14719..15240)
                     /gene="pyrR"
                     /locus_tag="VXE36_001468"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0779758.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15451..16080)
                     /gene="nth"
                     /locus_tag="VXE36_001469"
     CDS             complement(15451..16080)
                     /gene="nth"
                     /locus_tag="VXE36_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0779759.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16080..16622)
                     /locus_tag="VXE36_001470"
     CDS             complement(16080..16622)
                     /locus_tag="VXE36_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0779760.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVGDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16792..17109
                     /locus_tag="VXE36_001471"
     CDS             16792..17109
                     /locus_tag="VXE36_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0779761.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            17348..18907
                     /locus_tag="VXE36_001472"
     CDS             17348..18907
                     /locus_tag="VXE36_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0779762.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEISNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18951..19850)
                     /gene="htpX"
                     /locus_tag="VXE36_001473"
     CDS             complement(18951..19850)
                     /gene="htpX"
                     /locus_tag="VXE36_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0779763.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19852..20412)
                     /locus_tag="VXE36_001474"
     CDS             complement(19852..20412)
                     /locus_tag="VXE36_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0779764.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20506..21219
                     /gene="rsmG"
                     /locus_tag="VXE36_001475"
     CDS             20506..21219
                     /gene="rsmG"
                     /locus_tag="VXE36_001475"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0779765.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
BASE COUNT         6477 a         4535 c         3935 g         6373 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa atcaaagcac tgctttgagg ttgtagataa
       61 gactgacgaa gtcagctcaa aatactgttt tgaggttgca gatggaagct gacgtagttt
      121 gaagagattt tcgaagagta ttatatgaga aaaatcctct actctactaa tccacttaga
      181 aaaaacgcat attatcaagt gttaaaaact tgctaatatg cgttttatta tggaaatgtt
      241 gggttcattt tctcttaaaa ttgatttttt cttagaattc tagcttaggt catttttaaa
      301 attcaaattc cgcaagaaca tcttgcccac tggtgaccaa ttttgctcct tcttgaatca
      361 aatgatggca accgtctgat agtccatcta aaatgctacc aggaatagca aagacatcgc
      421 gtccttcttc cattgctcgc tcacacgtaa tgagactacc tgaacgcatc ttagcctctg
      481 ctacaatcac accacgacaa agtccagcaa tgatgcgatt acgggcagga aaatgaaatt
      541 tcagaggttg ttcgccaggt ccatattcac ttagaaccag atggtcattg ccgatgtagt
      601 cttgcaagcg tttattggct ttaggataaa acacatccag tcctgttcca atcactgcaa
      661 tggtttttcc gccattctga agagctgcca tatgagctgc tgtgtcaatg cccttggcca
      721 gaccactgac aataaccagt tcattttcca agccttgaat gactttttca actgacttag
      781 ctccctgttt gctacaagca cgactgccca cgaccgctac cttcgggaat ttcaggaggt
      841 caagatttcc cttgtaaaat aaaagtacag gcgcatcata tatttcactc aaatcccaag
      901 gataacagtc atctaaaata gagaaagatg gaaatttttg aaactctttc gacaaatgcg
      961 catcgtctat ctgaaaataa cgttccataa aaacggctgg attacggcaa cctgatatat
     1021 ctgcaatatc acccaacaaa agctcctgat caacattttc accgtattct agcactttca
     1081 aaatctgttg attggtcaaa cctgattttt ttaacttata gatttcatag tttgtgattt
     1141 tcataaataa ctccatttct ttttctactc atctatctat tcgtaaaagt tcgtaaaagt
     1201 tcgtaaaaaa tcaaaaaaca tccgactatt ttgccagatg ttggaatctt taattttcgt
     1261 ttttaagaat ttcttctaat ttacgatagt cttggacact atcgatctca taaatgctat
     1321 tgccttctaa ttcttcaaca tagacatcta gctctttgat attatcctta accatattgt
     1381 cccaatagag atcaacaaat tcaccacttg cataagcctt gtcgataaag ctgacaatct
     1441 tttctgcagt tggagcatcc cagaaggata caccactaag gatgcgacct gccttgctat
     1501 caacaataat gtcttgaacc ttgtagtcat ctccatagac caagaaccat tcgttggtac
     1561 aatcttcacg ataaacacta aaataagtcg aacgtgtcaa atcattgcgg aacatatttt
     1621 taaagagata attgtcagca tcaataacat agctgttggc caattcttct tttacaagat
     1681 agagagagta aaagttattg tagtcagcgt atttatcatt gaaaacgagg cgaacaccgt
     1741 atttttcttt taagtaatcg aattgttctt taagataacc aacaatgatg atgatgtcat
     1801 tgattccttt ttctttgaga aactcaattt ggtattcaat caaaggtttt tgattaacct
     1861 gaaccaaggc tttaggggta ttttcagtca taggacgcaa gcgagttccc aatcccgctg
     1921 ctaagataat ggctttcaca cgaatctcct ttattcttta ataataatat aaactccagc
     1981 aatgacgaca agtgacgtca taatggtcag catatctagc ggtgcaccca aaaaaacaac
     2041 tgcaaacaag accgtccata ctacatagct cacgttcaag cctgtagcct tggctggttg
     2101 caagcgattg atagcgatat aataagccaa gtaggaaatc atatcaaagg ctgcaaaaac
     2161 aatcatgaga cctagcaatt gtccattggc tactgcagta aatgactgat gagagaagag
     2221 cacaatcaca agataggaca agaacgaagt cacttgacgg attaagaggg cttcgatttc
     2281 actcagttca ctttccatag caaaggagct aagaacactc tcacttcccc atgcaatagc
     2341 acaaaccaaa gcacagagaa tcccaatgta gaaggaatta acctgttcaa ccttataggt
     2401 ctgggcaata atccctccaa taatcaagac aatcccaaat acagtatttt tcgaaatctt
     2461 gtgcttcaaa aagaagaaag ccaatagaac tgaaatcgca gggtaaatag ccgatacaga
     2521 tgaagctaaa gaacttccga tatacttaac tgcataaaga ttggcctgca taccgatagg
     2581 gcctgctagc aaggctccga tgataacact gacattgcga atatttaaga aaattgagag
     2641 gcgaactttc ccttctttta ccaagagaaa agctagtaag ataaagatgc tcaaaaaatc
     2701 atgagctgca gccaccacaa agggtgacaa atctgtaaaa atcgaaaaga tataagcact
     2761 aaccgttaga cccaagcccc agaaaatacc tgagagaagg ccaaaaggaa ctccgttttt
     2821 acttttcatc tgaacctcca taagaagcca aacctttaac agctctttgg taacgattca
     2881 caccatagtc accaaaatct tcaccttgct cttccttata gacagtccat agactccaaa
     2941 tagtatcttg taaaatttta taaatagcaa tcttttcatg agaaaccggt gtttggtcac
     3001 tctcatagtg agataagaaa gtttcttcct cttgggaagt gaattcagac tctaaaaaga
     3061 gggcagccaa atcccacatt ggatcattca ttgatgaata ttcccagtca atcaaataaa
     3121 gtcgtccttg aggtgattcg ataaagtttt caggcaccaa atcgatatga caagattttc
     3181 tgtcaacacc taagtcagcc agtcttttct ctaaggagaa gactgcattt ctaacagatt
     3241 catagttggc ataaggaatt tgttcttcaa tcaaggattc gtattttttg atttcttcaa
     3301 aaggagcaaa ttctcctctt aattccttag cagacgtatg aatagtttgt aatattggag
     3361 caattttgtc gaacttggtc ttgattgacg ttgaatcaag cgtaatcgca gattcgatat
     3421 actcatttac tttgatacca gcttcaatat caaaaagata attttttaca tctaagccta
     3481 aatcctttag tagttcaaga ttgtactttt catcttgtcg attgataagc ttttctgtcc
     3541 ctttaccaaa gaatttaaca atgtattgct tatttgttgt tttggccaaa tagttttgat
     3601 tggtcattcc acccagttgt tcaacactga ggacttcctc ttcttgacta agtaaggaag
     3661 aaattttttc tttaatgatt ttctccacaa ttaacctcca gtacttatac ttcccactta
     3721 aacactgttt taaaggctgt gtttaaatcg gttgcaaaga cacgatgaat atctttaatt
     3781 tctcttacag gttcttctag ataaaggata tttttaagac gattggcaaa tttcttgact
     3841 tccatcattt ggatagcatt tttaaaatca atgcgaccag aacgagatga cccaaccaaa
     3901 atcaagccct tttctaaggc atcgcgagta ttgagattga ctttatattc gctaactccc
     3961 atcatgagaa tcgttccctg aggacgaatg tagcgaatca agtcattaat agctggtcca
     4021 gtaccatcac caccacaaca ttcaaaagca tggtcaaagg ccaactcttc aggaatatta
     4081 tccgtaatat agcattcttt ggcaaatgag aagagttcca acttttccca atgacgacca
     4141 ataaccacaa tctctgattc tggcaaagta tagttgataa tattggcaac cacaaaagct
     4201 aaacttccat ctccaataac ggcgatccgc tcccgcttgc tatgagcaag agtcaataga
     4261 cgattcatag cgtgcatgcc cacactgaca aactctgtaa tggctgcaac cgtatcttca
     4321 atagcatcat aagccaccac acgatcttta gggagagaaa caaactctct cataaagcca
     4381 tcaaatccac tagacaagaa atgggtccct gtcatgtagt tttcatagaa ttcttcatca
     4441 ctctgcatag gagactgatt gggaatcatg acaacttttt gaccaacctc gtaggttccg
     4501 gtcgggtcag aaatgacggt tccacatgac tcgtgaatca ttgccattgg aagcttttta
     4561 ttcaaaatct tgggatcacg ttttccctga tagtaacgct gatccgcatg acagacagcc
     4621 atgtagttgg gacggataag gatatgattc tcttggtcaa tagcctcttc ctgatatttg
     4681 acattgataa acttaggctt agttagttga taaatttgat taatcatttt actagtcttt
     4741 ctcaatcata ctttttgcaa tcttcaaatc tgttacggtt gtaatcttca gatttgagta
     4801 ttcacctttg gccaaggcca catcttttcc tttgatcaca aagattttac atgcatctgt
     4861 caagatttcc ttctcttcat cagaaagaga tccataaagg tccatgaagt ccttgcaacg
     4921 gaatgtttga ggtgtttgtc cctgatagag gtgagcacga tttggaatac ctgtaatgaa
     4981 ttgcccattg gtactttcaa cgatagtatc cactgcttct accactgtgt ccactgcgtc
     5041 atgattttgg gcaagttgga tattgtcctg aatcatgcga agtgtaataa atggacgaac
     5101 agaatcgtgg gtaacaacga tatcctctga agtaagcgga cgataagcat caatggcttc
     5161 aatgatgttc tcaatacttg tattgcggtc agcaccaccc tttgtaatga tgatacgttc
     5221 cttataaaga ggaagatatt tatctacaag atcttctgca tgagaaaccc agtctccatg
     5281 aacaccaact acaatttttt caatacttgg ctccaagaca aatttttcaa ttgtatgaat
     5341 caaaataggt cgatcaccta gctctaaaaa ttgttttggc aagttactga tccccatgcg
     5401 tgtgccagtt ccaccggcaa gaattcctgc ataaatcatc tattttctcc tttgtcttac
     5461 taaaaaaact tattctctct attataccac aatctagtcc tatcataaaa gaaatactgg
     5521 tcctcccctt ctagaatagg agaattatgc agttctatta ttcaaagaaa ctagtccatt
     5581 tctagtaatg actaggaatt ctgtagcaat tactaataaa tgactgcgaa attttagagt
     5641 ccttcagaat aatatacttt ccttaaagaa aacttaaaat ttaagatttg aaacttcaaa
     5701 gtgattgctt ggcttactgc ccttcatttc ttattagcta actttatgat ataatgaaaa
     5761 acgaggtaaa ttgaatgaaa agtataaaat taaatgctct atcttacatg ggaattcgtg
     5821 tcttgaatat tatttttccc atcctaactg gaacctatgt cgcgcgtgtc ttggaccgaa
     5881 ctgactatgg ttacttcaac tcagtcgaca ctattttgtc atttttcttt ccctttgcaa
     5941 cttatggtgt ctatagctac ggtttaaggg ctatcagtaa tgtcaaggat aacaaaaaag
     6001 atcttaacag aaccttttct agtctttttt atttgtgcat cgcttgtacg attttgacca
     6061 ctgctgtcta tatcctagcc tatcctctct tctttactga taatccaatc gtcaaaaagg
     6121 tctaccttgt tatggggatt caactcattg cccagatttt ttcaatcgaa tgggtcaatg
     6181 aagctctgga aaattacagt tttctctttt acaaaactgc cttcatccgt atcctgatgc
     6241 tggtctctat tttcttattt gttaaaaatg aacacgatat tgttgtctat acacttgtga
     6301 tgagtttatc gacgctgatt aactacctga ttagttattt ttggattaaa agagacatca
     6361 aacttgttaa gattcaccta agtgatttta aaccactctt tctccctctg acagccatgt
     6421 tagtctttgc caatgccaat atgctcttca cttttttaga tcgcctcttc ctcgttaaaa
     6481 cagggattga tgtcaacgtt agttactata ccatagctca gcgaattgtg accgttatag
     6541 ctggggttgt aacaggtgca attggagtga gtgtgcctcg tctcagttac tatctgggga
     6601 aaggagacaa agaagcctat gtttctctgg ttaatagagg tagtcgaatc tttaacttct
     6661 ttatcattcc actgagtttt ggactcatgg ttttaggacc aaatgccatc ctactttacg
     6721 gtagtgaaaa atatatcgga ggcggcatct tgacctctct cttcgctttt cgtacgatta
     6781 ttctggcctt agataccatt cttggttccc aaattctctt taccaatggc tatgaaaaac
     6841 gtatcacagt ctatacagtc tttgctgggc tactaaattt gggcttgaat agtctcctct
     6901 ttttcaacca tatcgtggct cctgaatact acttactgac aactatgtta tcagagactt
     6961 ctctacttgt tttctatatc attttcatcc atagaaaaca actcatccac ttgggacata
     7021 tctttagcta tactgttcga tactctctct tttcactttc ctttgtagca atttatttcc
     7081 tgattaattt catgtatcct gtggatatgg tcattaattt gccatttttg attaatactg
     7141 gtttgattgt cttgctatca gctatctctt atattagtct acttgtcttc acaaaagata
     7201 gcattttcta tgaattttta aaccatgtcc tagccttaaa aaataaattt aaaaaatcat
     7261 aggagtttaa aatgaaacaa ctaaccgttg aagatgccaa acaaattgaa ttagaaattt
     7321 tggattatat tgatactctc tgtaaaaagc acaatatcaa ctatattatt aactacggta
     7381 ctctgattgg ggcggttcga catgagggct ttatcccttg ggacgacgat attgatctgt
     7441 ccatgcctag agaagactac caacgattta ttaacatttt tcaaaaggaa aaaagcaagt
     7501 ataagctcct atccttagaa actgataaga actactttaa caactttatc aagataaccg
     7561 acagtacgac taaaattatt gatactcgaa atacaaaaac ctatgagtct ggtatcttta
     7621 tcgatatttt ccctatagat cgctttgatg atcctaaggt cattgatact tgttataaac
     7681 tggaaagctt caaactgctg tctttcagta aacataaaaa tattgtctat aaggatagcc
     7741 ttttaaaaga ttggatacga acagcctttt ggttgctcct tcgaccggtt tctcctcgtt
     7801 attttgcaaa taaaatcgag aaagaaattc aaaaatatag tcgtgaaaat gggcagtata
     7861 tggcttttat cccttcaaaa tttaaggaaa aggaagtctt cccaagtggt acctttgata
     7921 aaacaatcaa tttacccttt gagaatttaa gccttcctgc acctgaaaaa tttgatacta
     7981 ttttgacaca attttatgga gattatatga ccctaccacc agaagaaaaa cgcttctaca
     8041 gtcatgaatt tcacgcttat aaattggagg attaggatgc aatatttaga aaaaaaagaa
     8101 attaaagaaa ttcaactagc cctgctggac tatattgatg agacttgtaa gaaacatgat
     8161 attccttatt ttctcagtta tggaaccatg cttggagcca tccgccacaa aggtatgatt
     8221 ccttgggatg atgatattga tatttccctt tatcgtgagg attatgagcg tttactgaag
     8281 attattgaag aagaaaatca ccctcgctac aaggttcttt cctacgatac atcttcttgg
     8341 tacttccata atttcgcatc gattttggac acttctactg ttatagaaga ccatgttaag
     8401 tacaagcgtc atgataccag ccttttcatc gatgtcttcc caattgatcg atttacagac
     8461 ttgagcattg tcgacaagag ctataagtat gtggctcttc gtcaactagc ttatatcaaa
     8521 aaatcacgag cagttcacgg tgatagcaaa ctaaaagatt ttcttagatt atgtagctgg
     8581 tacgctctcc gatttgtcaa tcctcgctac ttttacaaga aaattgatca actagtcaaa
     8641 aatgctgtaa ccaacactcc tcaatatgaa ggaggagttg ggatcggtaa ggaagggatg
     8701 aaagaaatct tcccagttga tacctttaaa gaactgattt taactgagtt tgagggccgt
     8761 atgttgcctg ttcccaaaaa atatgaccaa tttttaaccc agatgtatgg cgattatatg
     8821 acaccaccat caaaagaaat gcaagaatgg tatagtcata gtattaaagc ttatcgtaaa
     8881 agctgattga gggggattat acaaactact aagatagagg ttattcaaaa acataattta
     8941 gtagaaaatg aaatacatat tcccacaata aaacgcatca tatcaaggtt tttgaaaaac
     9001 cttgatatga tgcgttttat aattttaaag acttttttct atagtagatt gaaataagat
     9061 gcgaacgaat caattagaaa attcaaatta atttctagaa atattttagt atccctgtgt
     9121 actgttctaa attcagtttg ctatatctta tttttctatt taaatcgctt ctgtaacaaa
     9181 gctacgactt tcaagtacct taagcatagc attagctgta tctagcgctg tgaagagggg
     9241 caccccgtgt tcaatggctg aacgacgaat ttgctcacca tcttcgtcag cagttcgttt
     9301 tgttcctact gtgttaatga tagcttgaat tcttcctttg cgtacaaaac ttgggatatc
     9361 cttatcgtca tcaccaatct taccaacagg ttgggcttgc aagccatgac tagcaaagaa
     9421 ggctgctgtc ccttctgtcg caaggattcc ataaccaatg ttttggaaac gacgagccaa
     9481 gttcaaggct tcttctttgg catcatcagc gatggtaaag acgacattac caaaagttgg
     9541 caagtgtaga taagaagctt caaaggcttt atagagagct ttttccaaag tagcatcaga
     9601 acccataact tcacctgttg acttcatttc aggaccgagc aagctgtcta ccttagctag
     9661 tttggtaaag gagaagacag gtgccttgat atgaacacgg gtgctttcag ggtaaagtcc
     9721 attttggtag ccaagttctg ataaactttg accaagaatg agcttggtcg ctacttgagc
     9781 cataggaata ttggttacct tagataggaa tggaacggta cggctggcac gtggattgac
     9841 ctcaataacg tagacttttt catccttgat aacaaactgg atgttcatca ttccaaggca
     9901 gtgaagaccg attgctaagc gtttggtgta gtctgcgatg gtctcctgaa ccttttgcga
     9961 caaggtttgt ggtgggtaaa cagccattga gtcacctgag tggacaccag cacgttcgat
    10021 atgctccatg ataccaggaa tgagtacatt tttgccatct gaaatggcat caacttcgca
    10081 ctcttgccca acgatataag agtcgacaag aactgggtgg tctggactag ccttaacagc
    10141 agttcgcatg taagaacgaa ggtcttcttc gttttcaacg atttccatgg cacgtccacc
    10201 aagtacataa gatgggcgga caagaactgg gaagccaatc ttacgagctg caagagctgc
    10261 ttcttcttca ttggtagccg tttgtcctgg tggctgtgga atatccaatt ctttgagagc
    10321 ttgctcgaag aggtcacggt cttcggcacg gtctaggtca gcaacctgtg taccaaggat
    10381 ggtcacacct gcttttgcca atggctccgc aaggttgatg gctgtttgac caccgaactg
    10441 aacgataact ccctttggtt gttccaagtc aatgacgttc ataacatctt cgaatgtcaa
    10501 tggctcaaag taaagcttat ctgatacaga gaagtctgtt gaaacggtct ctgggtttga
    10561 gttcatgatg atagcttcat aaccagctgc ctggatagcc ttaacagagt gaacggttgc
    10621 gtagtcaaac tcaacccctt gaccgatacg gattggacct gaacctagga caagtacaga
    10681 ttctttatca gatctgatag attcattttc ccaaccatag gttgaataga aatatggcgt
    10741 ttcggagtcg aactctgccg cacaagtgtc taccatctta taaactggaa caatcttgtt
    10801 ttccaagcga agttggcgaa ctttatcatc agtcgttccc cagagttcag caatcttacg
    10861 gtctgaaaaa ccattaagtt tggctgtttt caaaacttct agatcttgtg gatgagcacc
    10921 caattcttgc tcaatttcaa agatatgcaa gagtttatca agatagaaga tatcaatttt
    10981 tgtaagctct gcaatttctt caggtgtgta accacggcga atggcttctg acacatagaa
    11041 gagacggtca tcttgggctt tgacaacctt ttcaatcaag gcatcatcag aaactgctgc
    11101 aagttcaggt atttcattgt ggtgcacccc aatttcaagg gagcggcagg ccttgagaag
    11161 agattcctcg atgttacgac cgattgccat gacttctcca gtcgccttca tttgtgtacc
    11221 gagacggcgt tcaccctttt caaacttgtc aaatgggaaa cgtggaatct tagcaactac
    11281 gtagtcaagg gctggttcaa acatggcata ggttgaacct gtaactgggt ttataacctc
    11341 atccaaggtc aaacctactg caatcttggc agccaactta gcaatcggat atcctgtcgc
    11401 tttagaagca agggctgacg aacgtgatac acgagggttt acttcgataa cataatactt
    11461 gaagctgtta ggatcaagag ctagctgaac attacatcca ccttcaatct tgagggcacg
    11521 aataatgctc aagctcgcat cacgaagcat ttggttttca tagtctgaca tggtttgcgc
    11581 aggggcaaat acaatggaat cccctgtgtg aatcccaact gggtcaaagt tttccatgtt
    11641 acaaacaacc aaggcattgt cagctgagtc acgcatcact tcgtattcaa tttccttgaa
    11701 accggcaatc gaacgctcaa tcaaacattg ggtaacaggt gacaatttca aaccattttc
    11761 agtgatttca cgcaattctt tctcgttggc acacatacca ccaccagtac caccaagggt
    11821 aaaggctgga cgaacgatga ctgggtagcc aattgtcgct gcaaaggcaa ttgcttcttc
    11881 tactgtgtta acaatttcag attctggaat gggttgctca agctcttcca tcaattgttt
    11941 aaagaggtca cggtcctccg cttggtcaat ggcagacaat ctagtaccga gaagctctac
    12001 accaagctca tctaagatac catttttaga caattccatg gccatgttga gacctgtctg
    12061 accaccgagt gttggtagca aggcatctgg acgttcctta cgaagaatac gtgtcacaaa
    12121 ctcaagtgta atcggttcaa tgtaaacctt atcagcaatt tccttgtccg tcatgatggt
    12181 tgcaggattt gagttaacca aaacaacctc ataaccttcc tctttcaacg acaagcaagc
    12241 ctgggtccca gcgtagtcaa actcagcagc ctgaccaata ataatcggac cagaaccaat
    12301 caccataatt ttttgaatat cagtacgttt aggcatagtt tatgatacaa agcccgtaaa
    12361 gaacacagtg aaaataggaa actcggcgca gacgccttca gcgtcaagac gatgtttatc
    12421 tttttcacac agttcttagg gcgtgttcac ttccgcgaac aatgtatctt ctcctttcta
    12481 ttcgtcgcct ctcagggcga cattaaataa gatacaaagg acgaatagaa agcgattgaa
    12541 ttttagaaaa tcaaggaagg attgacaatc caagttggtt tctctacatt ctgagctttc
    12601 cgtccgtgtt cagttacata aattctccga cgagctttta ctcgttctta gtttgattgt
    12661 ttaaaaactt ccatcatctc gataaactcg tcaaataggt agctagcgtc gtgtggccca
    12721 ggagctgcat ctgggtggta ttgaacagag aaagcaggtt ggtatctgtg gcgcacacct
    12781 tccactgact tgtcattgat ttcttcgtgg gtaataatca agtgctctgg caaatcctcg
    12841 cggctgactg cataaccatg gttctggctg gtgaagtcta ctcgtcctgt tgcgatttca
    12901 cgtaccgcat ggttgaatcc acggtggcca aacttcatct tataggtctt agccccgttt
    12961 gccattgcaa agagttggtg tcccatacaa ataccaaaga ttggaatttt tccttgtaca
    13021 ccgcgaatca tgtcgagtgc ttgtggaacg tcttctgggt tacctggacc atttgacaac
    13081 ataactccat caggattgag atggagaatt tcttcagccg ttgtcgaata aggaacaact
    13141 gtcacgttac agttgcgttt agaaagttca cgtaggattg agtgcttgag accaaagtcc
    13201 actagcacca cgctcaaacc aactcctgga gctggataag acgttttagt agaaacctgt
    13261 ttgatattgt ctgtcggtaa aactgttgct tggagctggt ctgtcacatg gtccatactg
    13321 tccccaacat gggtcaaggt tgcacgcata gtaccatgct tacggataat cttggtaaga
    13381 gcacgcgtat caattcctga aatccctgga attttcttgg ctttcaaaaa ttcatccaag
    13441 gtcatttggt tgcgccagtt gctagctcta cgcgcttctt caaaaacaac gactccctta
    13501 caagttggaa taatggattc ataatcatca cgattaatac cataatttcc taccaaagga
    13561 taagtaaagg tcaagatttg tccattataa gactggtctg taatggattc ttggtagccg
    13621 gtcatccctg tattaaagac gatttcgcct gttacatcaa tatctgctcc gaaggccttg
    13681 ccttcaaaaa ctgtgccatc ttctaatact agaattcttt ttgtcatatt ttcacctctc
    13741 gtggacgctc actggcgtct tttaacgtct tgtgttttag ttggcgtttc tactcgctag
    13801 tacggattct aagattgcca ttcgaacaaa gacaccattg gtcatttgtt ggacaatccg
    13861 tgattttggt gcttcaacca agtggtctgc tatttctaca tcacgattga ttggagctgg
    13921 gtgcatgagg attgctgttt ctttcaaacg atcgtaacgt tcttgagtca agccatgttg
    13981 ggcatggtag tcttcttttg aaaatacagc tccactatca tggcgttcgt gttgcacacg
    14041 gagaaacatc atgacatcaa cctgatcaat gatttcatca atggttacaa actttccata
    14101 gtctgcaaac tcttgacttc tccattcctc aggtccagcg aaaaagagtt cagctcccaa
    14161 gcgtttcaaa atctgcatat tggatttggc aacgcgtgag tggtccaagt cacctgcaat
    14221 agcaacttta agaccctcaa agtggccaaa ttcctcataa atggtcatca aatcaagcaa
    14281 gctctggcta gggtgttggc ccgaaccatc tccaccattg atgatggaag tcgtaatcgt
    14341 tggactagca atcaattctc tatagtagtc gacctctgga tggcgaatca cacagacatc
    14401 cactcctaaa gcagacagag tcaaaatggt gtcataaagt gtctcaccct tattaaccga
    14461 actagtcttc acatcaaagt caagtcgttc caatccaagt ttaatctctg cgacttcaaa
    14521 ggacttatgt gtccgtgtag aatcctcaaa gaagagattg gaaacaatcg gatggtcttc
    14581 atagggaagc tgggctccat ttttaaactc aattcctcgc ttgatcaatt tcattacttg
    14641 atcgacagtg aggtcttcca tggacaccac atggttcaat gcttgttgat tttctgacat
    14701 ggctactcct ttaactttct aagcttcttc agtaatcaga actctgtctt ggtcatcaag
    14761 ttctgtcatc tctacgatga tttcttcaga acgactggtt gggatatttt ttccaacgta
    14821 atctggacgg attggcaatt ctctatgtcc acgatcgact agaactgcta aactcacacg
    14881 cgcaggacga ccatgaccga caatattatc aatagcagca cggatggtac gacctgtata
    14941 gagcacatca tccaccaaga taacttcgcg gtctgtcaca tcgacagaaa ccaaagaagt
    15001 atcttctcca cttttaacat catcacggaa aggtttagta tccaattcca caacaggaac
    15061 tgaaagattt tctaactgct tcaaacgttc ttggattcgg tgggcaataa agacaccacg
    15121 agttttaata ccagccaaga cgatcttatt caaatctttg ttgcgttcga taatctcata
    15181 agtaatacgc gtaatcgctc gtttgacggt caattcgtct acaacttctt ttgttttcat
    15241 gacaaacctc caaaaagaaa agtctcctta aacaaggaga cttgaaattt atagccaagc
    15301 gagccctact gcacacagta tagacttcac ccttctactt tatcgcgctc cttgcctgcc
    15361 tcacgggaca ggtttaaagg aatatttagt tatcatttac tatagcacaa agcatgctta
    15421 aaatcaagca aaaagtttca atgtagcatc ttacaaattg ctaaaatcat ataattgtgg
    15481 gtactggtca cactctggat tttttggatg gcaaatggct cttccaaaat aaatcatggc
    15541 ctgatgggca gctaaccact gctcaggcgg caagatatcc atgacccgct tttccacctc
    15601 aagtggcgtc gctgattttt tgacaatatc gtggtgtttg caaatacgct ccacatgagt
    15661 atccactgca aaggctggaa tcccaaatcc tacactcatg acaacattgg ctgtcttgcg
    15721 accaacacct gccaaactct ccaattcttc acgtgtctga gggacttgac catcaaaatc
    15781 gtctagtaac tgttgggcac attttttaag gaatttagct ttattccgat acaatcccaa
    15841 gcgagaaata tgtgaagcaa tctcactctc tgtcgctaca gacatagctt ggggtgttgg
    15901 aaaggcaaca aagagacctg gtgtggcctt atttaccgct gcatctgtcg tctgggctga
    15961 taacatgacc gcaaccagga gttcaaaatg attggtaaaa tcaagactag gcttggcatc
    16021 tgggaagagg gcaatgattt cttctagcac ctttcgtgct cgtttttttg acaagaccat
    16081 tattcatctc cgtcaaatag tccttgtaag ccagcaaaag gactgttttc ttctttcttt
    16141 actgcttttt gagcttggta ttcttcctct gtcatgattt gccagtcatt tcctgagata
    16201 aatccttgac cagcttcttc ttcagccgtc aagaccttga taggaatgtt tagcaggata
    16261 ttgtctgata cactctcagc aaggtcaagc tccccatttt cgatgggcaa gaccaagtca
    16321 tcatctaaaa cttcttgatc tagctggtta gttgcgcctt ccatgaaaac ttccgtgact
    16381 ggataagatt caactaactc aactggctcc atactgcgac tcgaagcaag aacaatggta
    16441 taagatagtt gataatctaa gaaatacata cggtcttcat attgtacttt cccaactgca
    16501 aggatatctt ttacatctaa aatttcttga ttacgtgcac gcaggtcacc aactaaatct
    16561 aacgtttgtt caaagttcaa accttcagac tgcttacgaa tttcttgaat atttaatttc
    16621 atacttcctc cataaagatt tactctcttg attataccat gaaaaggcta caaatcagca
    16681 caccaaactt tgtaattaaa attcaaaatt ttaacatatt tactatgaca gttttgtttt
    16741 ttagtgctat actataggga aagagtacat cagatcaagg aggatgctca catggaagac
    16801 aagaaactca ttcaactcct atccaagtta aataaaagct accaaaactg taaacagggt
    16861 acggcagatg atattcgact acaagagctg ctaaacacta ctatgcaaga gctcaaaaaa
    16921 acggaaaagt tgaacaacag tatcttaatt gatcttgaga aattttacca acccaccagt
    16981 cctctgattg gactgggtag cctaaaacta aacaatcaag cacgcactgc ttggcgaaac
    17041 tatgataaat tccattacga gcatgtcaaa cacgtactaa gtctctatgg acctgttttt
    17101 gaattttaga gcatagaatt tccagttttc tgttgacaaa atttccttaa aggtataata
    17161 taaagatact aatactcgga ggtaagggag acatgaacaa ctaagtctat caaataaaga
    17221 acctttattt agtagatctt gtttttgtct ctttttgtgt gctcttttat gctctttttc
    17281 tggcatgtta atagagtttt tttgacatag actttgggct ctactaggta aagtagagct
    17341 ttttgttatg cactatgaac attctagaaa gggaaatcat atgataaaaa tcaatcatct
    17401 aaccatcaca caaaacaaag atttacgaga tcttgtatct gacctaacca tgaccatcca
    17461 agacggggaa aaggttgcta ttattggtga agaaggaaat ggcaaatcaa ccttacttaa
    17521 aattttaatg ggggaagctt tgtctgattt cactatcaag ggaaacatcc aatctgacta
    17581 tcagtcactg gcctacattc ctcaaaaact tcccgaggag ctgaaaaaga aaactttaca
    17641 cgactacttc tttttagatt ctattgattt agactacagt atcctctatc gtttggcgga
    17701 ggaattgcat tttgatagca atcgtttcgc aagtgaccaa gagattagca atctatcagg
    17761 gggagaagct ttgaaaattc agcttatcca tgagttagcc aaaccctttg agattctatt
    17821 tttagatgaa ccttcaaatg acctagacct tgagacagtt gattggctaa aaggccagat
    17881 tcaaaagacc agacaaaccg ttattttcat ttcccatgat gaagactttc tttctgaaac
    17941 ggcagacact attgttcact tgcgactggt caaacaccgt aaagaagcgg aaacgctagt
    18001 agagcattta gactatgata gctatagtga gcagagaaag gctaattttg ccaaacaaag
    18061 tcagcaagct gctaacaacc aaagagccta cgataaaacc atggaaaaac atcggagagt
    18121 taagcaaaat gtagaaactg cgcttcgagc taccaaagat agtactgccg gtcgcctatt
    18181 ggctaaaaag atgaaaactg tcctctcaca agaaaaacgc tacgaaaagg cagctcagtc
    18241 catgactcaa aagccacttg aagaggaaca aatccaactt ttcttttcag acatccaacc
    18301 attaccagct tctaaagtct tagtccaact ggaaaaagaa aatttgtcca ttgacgaccg
    18361 agttttggtt caaaaactac aactaactgt ccgtgggcaa gaaaaaatcg gtattatcgg
    18421 gccaaatggt gttgggaaat caactctgtt agccaaatta aagcaacttc tgaatgataa
    18481 aagagagatt tcccttggtt ttatgccaca agattaccac aaaaaactgc aattggattt
    18541 atcaccaata gcttatatca gcaaaactgg ggaaaaagag gaacttcaga aaatccaatc
    18601 tcacctagcc agtctcaatt tcagttatcc agaaatgcag catcaaattc gctccttatc
    18661 tggcggacaa cagggaaaac tcctgctttt ggatctagtc ctgcgcaaac caaactttct
    18721 cctgctggat gaacccacac gaaacttttc tcccacttct caaccccaaa tcagaaaact
    18781 ctttgcaacc tatccaggcg gtctcatcac tgtttcgcat gaccgtcgtt tcttaaaaga
    18841 agtctgctcg atcatctatc gcatgacaga acacggtttg aagctagtta atttagaaga
    18901 tttataaatt tgcaacatag caaaaatcca gagacgacct ctggattctt ttacatctgt
    18961 tttaaacgtt caatccgttc tgagataggt gggtgggtat aaaagagttt ttggaacccc
    19021 ccacctttct taggatcatt gatataaagg gcactgctag catcatcgac gtggcgactc
    19081 ataggtttgc tattgtccaa cttatctagg gcattaatca ttccctgggg attgcgagtc
    19141 agctcgacac tagatgcatc tgccagaaat tccctctgac gagaaatagc gagctgaacc
    19201 aaggttgcag cgagaggtgc cagtacaata gctagtaggg aaaccactag cataatgatt
    19261 tcaagaccat ttccatctcg gtcatcatca cttcgtctgc gacctgctcc accccaccac
    19321 atcatacgac ctgccatact agaaagcatg gtgatagcac tagcaagggc aactgcaata
    19381 gtcgaaatac ggatatcata attacgaata tgactgactt catgtcccat aacagcttct
    19441 agttcttcac gattcatgat agctagtaga cctgaagtcg cagcaacagc cgcattttga
    19501 ggattagaac ctgtcgcaaa ggcatttaag gctggatcat caatgatgaa aacacggggc
    19561 ataggaatct gagcgaccag agccatatct tccactacat ggtagaggtc tggtgccgtt
    19621 tgctcatcca cctcacgcgc tccattcatg gacatgacaa tctctgtcga ttgaaaaatc
    19681 atagacaaag cgtagataaa gccgataatc agtgcaataa ccaaaccacc aagtccagat
    19741 cttataaaga gataaccaac cgcataacca acaagagcta agagtaggaa aaataccagc
    19801 aacaaaatcc aggtttttcg tttattgctt gcaatttgat caaacaacat cttagtcacc
    19861 taaaccgcta aaatcaactt taggaaccga cttttcctct tcaggtgttt gaaggaaatc
    19921 tgccgcttta aatccaaaca ttccagcgat aatattgctc gggaaagttt ctaattttac
    19981 attgtagttg ctgacaacac tgttatagag ttgacgagag taagaaattt tattttctgt
    20041 gtttgtcaac tcctcttgca atttaacaaa gttagcacta gctttcaaat ctggatagct
    20101 ttctgcaact gcaaaaatac ctgaaacctg acgagtgagg gcatcactgg ctttcatagc
    20161 ttctgctggt gaagtcgctg ccgccacttg gttacgtagt tctgccacct tttcaagggt
    20221 agaaccttca tatttggcat aaccttttac agtctcaatc aagtttggca agaggtcatt
    20281 tcgacgtttc aactgaacat caatctgact ccaagcctcc ttggtttgca tacgattttt
    20341 aaccaaaccg ttatagctaa caatcacaaa aataacaata agagcgataa ctccaagaat
    20401 aatccaagtc ataatataag tcctttctgc ttttagatta gtaccagtat atcaaatttt
    20461 ctatgattgt ggtaaaataa gatgatacta aagaaggaaa taactatgaa accaaaaaca
    20521 ttttacaact tgcttgccga gcagaatctt ccactttcgg accagcaaaa agaacaattt
    20581 gaacgttatt ttgagctctt ggtcgagtgg aatgagaaga ttaatttgac ggcgattacg
    20641 gacaaggaag aagtttatct caaacatttt tacgattcga ttgcacccat tcttcaaggt
    20701 ttgattccca atgaaactat caaacttctt gatatcgggg ctggggcagg atttcctagt
    20761 ctaccaatga aaattctcta tccggagtta gatgtgacca ttattgattc actcaataag
    20821 cgcatcaact tcctacaact cttggctcaa gaactggatt tgaacggagt tcatttctac
    20881 cacggacgtg ccgaagattt tgcccaagac aagaacttcc gtgctcaata tgattttgta
    20941 acagctcgtg cggttgcccg tatgcaggtc ctatctgaat tgaccattcc ctaccttaag
    21001 gttggtggaa aactattggc actcaaggcc agcaatgcgc ctgaggaatt attagaagct
    21061 aagaatgccc tcaatctcct ttttagtaag gtcgaagaca atctcagcta cgccctaccg
    21121 aatagagatc cgcgctatat cacagtggta gaaaagaaaa aagaaacacc aaataaatat
    21181 ccgcgtaagg ctggtatgcc aaataaacgc ccactttaaa ttttttagta aacaaatgtt
    21241 tacaaaatca gcctcgctct tttatttcta ggctcgggaa aaaatgattt acaaaatcag
    21301 cctcgctctt ttatttctag
//
LOCUS       DAVLHB010000036        20680 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLHB010000036 DAVLHB010000000
VERSION     DAVLHB010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.036"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(131..1057)
                     /gene="cysK"
                     /locus_tag="VXE36_001476"
     CDS             complement(131..1057)
                     /gene="cysK"
                     /locus_tag="VXE36_001476"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0779766.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVYAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
     gene            complement(1342..1977)
                     /locus_tag="VXE36_001477"
     CDS             complement(1342..1977)
                     /locus_tag="VXE36_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0779767.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2033..3331
                     /locus_tag="VXE36_001478"
     CDS             2033..3331
                     /locus_tag="VXE36_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0779768.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     SIILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3328..3990
                     /locus_tag="VXE36_001479"
     CDS             3328..3990
                     /locus_tag="VXE36_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0779769.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4070..4618
                     /gene="raiA"
                     /locus_tag="VXE36_001480"
     CDS             4070..4618
                     /gene="raiA"
                     /locus_tag="VXE36_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0779770.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            4754..6727
                     /locus_tag="VXE36_001481"
     CDS             4754..6727
                     /locus_tag="VXE36_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0779771.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            6724..7176
                     /gene="rplI"
                     /locus_tag="VXE36_001482"
     CDS             6724..7176
                     /gene="rplI"
                     /locus_tag="VXE36_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0779772.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7220..8572
                     /gene="dnaB"
                     /locus_tag="VXE36_001483"
     CDS             7220..8572
                     /gene="dnaB"
                     /locus_tag="VXE36_001483"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0779773.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8574..8840
                     /locus_tag="VXE36_001484"
     CDS             8574..8840
                     /locus_tag="VXE36_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779774.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            8929..10275
                     /gene="cbpD"
                     /locus_tag="VXE36_001485"
     CDS             8929..10275
                     /gene="cbpD"
                     /locus_tag="VXE36_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0779775.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10358..10460
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10531..10821
                     /locus_tag="VXE36_001486"
     CDS             10531..10821
                     /locus_tag="VXE36_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0779776.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            10784..11542
                     /locus_tag="VXE36_001487"
     CDS             10784..11542
                     /locus_tag="VXE36_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779777.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            11581..12588
                     /locus_tag="VXE36_001488"
     CDS             11581..12588
                     /locus_tag="VXE36_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0779778.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12588..13316
                     /locus_tag="VXE36_001489"
     CDS             12588..13316
                     /locus_tag="VXE36_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779779.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13435..13893
                     /locus_tag="VXE36_001490"
     CDS             13435..13893
                     /locus_tag="VXE36_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0779780.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGR"
     gene            13895..16327
                     /locus_tag="VXE36_001491"
     CDS             13895..16327
                     /locus_tag="VXE36_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0779781.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKANHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            16648..17301
                     /gene="rr06"
                     /locus_tag="VXE36_001492"
     CDS             16648..17301
                     /gene="rr06"
                     /locus_tag="VXE36_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0779782.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17298..18629
                     /gene="hk06"
                     /locus_tag="VXE36_001493"
     CDS             17298..18629
                     /gene="hk06"
                     /locus_tag="VXE36_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0779783.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            18712..19239
                     /locus_tag="VXE36_001494"
     CDS             18712..19239
                     /locus_tag="VXE36_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0779784.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19315..>20680
                     /locus_tag="VXE36_001495"
     CDS             19315..>20680
                     /locus_tag="VXE36_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV0779785.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLFMGSVVHATEKEVTT
                     QVATSSNKANKSQTEHMKAAEQGKQHREIDLDRNKAKKAIDEYIEKMLSEIQLDKRKH
                     TQNFALNIKLSRIKTEYLYGLSVLKEKSEAELPSKIKEKLTAAFEQFKKDTLKPGEKV
                     AEAKKKVEEAEKKAKDQKEEDRRNYPTITYKTLELEIAESDVEVKKAELELVKEEANK
                     PRNEQKVKQAKAKVESKQAEATRLKKIKTDREEAEEEAKRRAEAKLKEAVEKNTATSE
                     QGKPKRRGKRGALGEQATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAQKKVAE
                     AEKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKESRNEEKIKQ
                     VKAKVESKQAEATRLENIKTDRKKAEEEAKRKAAEEDKVKEKPAPAPQPAPAPQPEKP
                     TEEPE"
BASE COUNT         6528 a         3392 c         4718 g         6042 t
ORIGIN      
        1 atagtggatt tacccactac aaatattata gagccatttt ttgtatgcag tcgatcctta
       61 tagggagagc ttcctatttt caaggtaaaa ataaaaagcc ctataataag ggccaattgt
      121 atttaggaga ctaaacttca aattcataga gtgctgtaga gagataacgt tcaccgttat
      181 ctggtgctag agcaaggact tttttacctg tacctaattt tttggcaacc tcgatggctc
      241 cgtagatagc tgcagctgag gaaatcccta caaggaagcc ttcttttcca ccaatttcac
      301 gtccgagtgc aagagcatca tctgatgtta cacgaacgat accatcatag gctttagtat
      361 caagtgtatc aggaataaat ccagctgaga taccttgaat tttgtgagga ccaggttttt
      421 caccagatag aatagcagat tcatcagctt ccactgcata aacttgaatg ttagaatttt
      481 ctgatttgag tgcatgagaa acaccagaaa tcgttccacc ggtacctact ccagcaacaa
      541 aggcatctaa tccatcttta ccgaaagcag ctagtatctc agctcctgtt gttctttcgt
      601 gtacttctgg attagctgga ttgtcaaatt gaagaggaag gaaaccatca cgttcagcag
      661 cgatttcttg agccttagca atagcacctt tcattccctc gctaccagga gttaggacga
      721 gttcagcacc ataagcttgg ataattttac gtcgttctac actcatagtt tcaggcataa
      781 cgatgacgac tttataccct ttagcagcac ctacccatga aagtccaata ccagtgtttc
      841 cacttgttgc ttcaacaata gtagaaccag gtttcagaat accatcttgt tcagcttttt
      901 caatcatgct aagggcaata cggtctttta cagatgaacc aggattaaat gcttcaagct
      961 ttatatagac gtctgcagca ccttctggca cgatgttgtt aagtttaaca atcggtgttt
     1021 gaccgattaa ttcagtaatg ttgttataaa tagacatatg aatacctctt tgtataagat
     1081 atctttagta taacgctatc tataccattt gtaaaatata gaaatcctat cgaagcgata
     1141 ggatttctat atatcataga tcaaagtcat taattttcaa gtgattgcgt tcagctaatt
     1201 ctagtaaata ggtgtgaagg aaaacgatat caggtttcgt ttgaattgct tcattttcta
     1261 gtatattttg gtacgcatct ttttattttg ctcgctaaag tagttgtgag aatgtcaacg
     1321 aaacgctgta ttattcattg tttacactaa gtttacagga acttcaacct ctcgtaaacc
     1381 ttggtcagtt aaagtgactt ttccattaaa aaactccaca agtgcagctt taatagtttc
     1441 tttttcttct ttatcaacat aaatcatcgt atcgacttga tctgtaaagt ttgtatccag
     1501 ctccatgaga tcatgttctt taaggaagtt actgtactct tggtactgag cataagacat
     1561 ttgaatagca atgccagcct gttcttttat ttcaataata ccaatttctt tgacagctaa
     1621 ggcgacactg ccggcgtaag cacgaattag tcctccagcg cctagtttaa taccaccaaa
     1681 gtagcgtgtc acgaccacac agacattggt gagattgtga ttttctagta ccccaagcat
     1741 gggaacacca gcagtaccac taggttcacc atcatcactt gtacgtttaa tttcactacg
     1801 ttctccaata ataaaggcag agcagttatg tgtcgctttg tagtgttctt ttttgatggc
     1861 agtaatgaag tcacgagcct cttcttcgct ataaacacgc ttggcatggc agataaagcg
     1921 agattttttg atttcttctt ggacttgacc gtcctcttta attgttctaa attccatgat
     1981 ttaattgtac taaaaaatca tctaaagtgc tagtttttac gaataaagaa gtatgaaagt
     2041 aaatttagat tatctcggtc gtttatttac tgagaatgaa ttaacagaag aagaacgtca
     2101 gttggcggag aaacttccag caatgagaaa ggagaagggg aaacttttct gtcaacgctg
     2161 taatagtatt attctagaag aatggtattt gcccatcggt gcttactatt gtcgagagtg
     2221 cttgctgatg aagcgagtca gaagtgatca aactttatac tattttccgc aggaggattt
     2281 tccgaagcaa gatgttctca aatggcgcgg ccaattaact ccttttcaag agaaggtgtc
     2341 agagggactg cttcaagcag tagacaagca aaagccaacc ttagttcatg cggtaacagg
     2401 agctggaaag acagaaatga tttatcaagt agtggctaaa gtgatcaatg cgggtggtgc
     2461 agtgtgtttg gctagtcctc gcatagatgt ttgtttggag ctgtacaagc gcctgcaaca
     2521 ggatttttct tgcggaatag ctttgctaca tggagaatcg gaaccttatt ttcgaacacc
     2581 actagttgtt gcaacaaccc atcagttatt gaagttttat caagcttttg atttgctgat
     2641 agtggatgaa gtagatgctt ttccttatgt tgataatccc atgctttacc acgctgtcaa
     2701 gaatagtgta aaggagaatg gattgagaat ctttttaaca gcgacttcga ccaatgagtt
     2761 agataaaaag gtccgtttag gagaactaaa aagactgaat ttaccgagac ggtttcatgg
     2821 aaatccgttg attattccaa aaccaatttg gttatcggat tttaatcgct acttagacaa
     2881 gaatcgtttg tcaccaaagt taaagtccta tattgagaag cagagaaaga cagcttatcc
     2941 gttactcatt tttgcttcag aaattaagaa aggggagcag ttagcagaaa tcttacagga
     3001 gcaatttcca aatgagaaaa ttggctttgt atcttctgta acagaggatc gattagagca
     3061 agtacaagct tttcgagatg gagaactgac aatacttatc agtacgacaa tcttggagcg
     3121 tggagttacc ttcccttgtg tggatgtttt cgtagtagag gccaatcatc gtttgtttac
     3181 caagtctagt ttgattcaga ttggtggacg agttggacga agcatggata gaccgacagg
     3241 agatttgctt ttcttccatg atgggttaaa tgcttcaatc aagaaggcga ttaaggaaat
     3301 tcagatgatg aataaggagg ctggtctatg aagtgcttgt tatgtgggca gactatgaag
     3361 actgttttaa cttttagtag tctcttactt ctgaggaatg atgactcttg tctttgttca
     3421 gactgtgatt ctacttttga aagaattggg gaagagaact gtccaaattg tatgaaaaca
     3481 gagttgtcaa caaagtgtca agattgtcaa ctttggtgta aagagggagt tgaagtcagt
     3541 catagagcga tttttactta caatcaagct atgaaggatt ttttcagtcg gtataagttt
     3601 gatggagact tcctgttaag aaaagttttc gcttcatttt taagtgagga gttgaaaaag
     3661 tacaaagagt atcaatttgt tgtaattccc ctaagtcctg atagatatgc taatagagga
     3721 tttaatcagg ttgagggctt ggtagaggca gcaggctttg agtatctgga tttattagag
     3781 aaaagagaag agagagccag ttcttctaaa aatcgttcag agcgcttggg gacagaactt
     3841 cctttcttta ttaaaagtgg agtcactatt cctaaaaaaa tcctacttat agatgatatc
     3901 tatactacag gagcaactat aaatcgtgtt aagaaactgt tggaagaagc tggtgctaag
     3961 gatgtaaaaa cattttccct tgtaagatga ggaaaaaatt tgcaaaaata gaatgaaagc
     4021 gttataataa aatcataaaa acaaaaatgt ttagaaagaa ggtactcata tgattaaata
     4081 tagtatccgt ggtgaaaacc tagaagtaac agaagcaatt cgtgattatg tagtttctaa
     4141 actcgaaaag atcgaaaagt acttccaacc agaacaagag ttggatgccc gaattaactt
     4201 aaaagtttat cgtgaaaaaa cggctaaagt ggaagtaacg attccgcttg gatctattac
     4261 tctccgcgca gaagatgtat ctcaagatat gtatggttca attgaccttg taactgataa
     4321 aattgaacgt cagattcgta aaaataaaac aaaaatcgag cgtaaaaata aaaataaggt
     4381 agcaactggt caattattta cagatgcttt ggtggaagat tcaaatgttg tccagtctaa
     4441 agttgttcgt tcaaaacaaa ttgatttaaa accaatggat ttggaagaag caattctaca
     4501 aatggattta ttggggcatg atttctttat ctatgtggat gttgaagatc agacaaccaa
     4561 tgtgatttat cgtcgtgagg atggcgaaat tggtttgtta gaggttaaag aatcttaatt
     4621 tcaatatgtg taaaggtagg tttactgaat tgtaaactac ctttttctta taattgatag
     4681 aattactgat tacactttta aaaagtcgct ttttgagggg tattatggta taatgggtgc
     4741 caagaggttt tgaatgaaaa aattttatgt aagtccaatt tttcctattc tagtaggatt
     4801 gattgcgttt ggagtcttat ccactttcat tatttttgtt aataataatc tgttgacggt
     4861 tttaattttg tttctttttg taggaggcta tgttttttta tttaagaaac tgagagtgca
     4921 ttatacaagg agtgatgtag aacagataca gtatgtaaac caccaagcgg aagaaagttt
     4981 gacatctcta ttggaacaaa tgcctgtagg tgttatgaaa ttgaatttat cttctggaga
     5041 ggttgagtgg tttaatccct atgctgaatt gattttgacc aaggaagatg gtgattttga
     5101 tttagaagct gttcaaacga ttatcaaggc ttcagtagga aatccgtcta cttatgccaa
     5161 gcttggtgag aagcgttatg ctgttcatat ggatgcttct tccggtgttt tgtattttgt
     5221 agatgtatcc agggaacaag ccataacaga tgaattggta acaagtcgac cagtgattgg
     5281 gattgtctct gtggataatt atgatgattt ggaggatgca acttctgagt cagatattag
     5341 tcaaatcaat agttttgtag ctaattttat atcagagttt tcagaaaaat acatgatgtt
     5401 ttctcgtcgg gtaagtatgg atcgatttta tctatttact gactacacgg tgcttgaggg
     5461 cttgatgaat gataaatttt ctgttattga tgctttcaga gaagagtcga aacagagaca
     5521 gttgcccttg accttaagta tgggattttc ttatggcgat ggaaatcatg atgagatagg
     5581 gaaagttgct ttgctcaatt tgaacttggc tgaagtacgt ggtggcgacc aggtggttgt
     5641 taaggaaaac gacgaaacga aaaatccagt ttattttggt ggtgggtctg ctgcttcaat
     5701 caagcgtaca cggactcgta cgcgcgctat gatgacagct atttcagata agattcggag
     5761 tgtagatcat gtttttgtag tcggtcacaa aaatttagac atggatgctt tgggctctgc
     5821 tgtaggtatg cagttgttcg ccagcaatgt gattgaaaat agctatgctc tttatgatga
     5881 agaacaaatg tctccagata ttgaacgagc tgtttcattc atagaaaaag aaggagttac
     5941 gaagttgttg tctgttaagg atgcaatggg gatggtgacc aatcgttctt tgttgattct
     6001 tgtagaccat tcaaagacag ccttaacatt atcaaaagaa ttttatgatt tatttaccca
     6061 aaccattgtt attgaccacc atagaaggga tcaggatttt ccagataatg cggttattac
     6121 ttatatcgaa agtggtgcaa gtagtgccag tgagttggta acggaattga ttcagttcca
     6181 gaattctaag aaaaatcgtt tgagtcgtat gcaagcaagt gtcttgatgg ctggtatgat
     6241 gttggatact aaaaatttca cctcgcgagt aactagtcgg acatttgatg ttgctagcta
     6301 tctcagaacg cgcggaagtg atagtattgc tatccaggaa atcgctgcga cagattttga
     6361 agaatatcgt gaggtcaatg aacttatttt acaggggcgt aaattaggtt cagatgtact
     6421 aatagcagag gctaaggaca cgaaatgcta tgatacagtt gttattagta aggcagcaga
     6481 tgccatgtta gccatgtcag gtattgaagc gagttttgtt cttgcgaaga atacacaagg
     6541 atttatctct atctcagctc gaagtcgtag taaactgaat gtacaacgga ttatggaaga
     6601 gttaggcggt ggaggccact ttaatttggc agcagctcaa attaaagatg taaccttgtc
     6661 agaagcaggt gaaaaactga cagaaattgt attaaatgaa ataaaggaaa aggagaaaga
     6721 agaatgaaag taatcttttt agcagatgtt aaaggaaaag gtaaaaaagg cgaaattaag
     6781 gaagtaccaa cagggtatgc gcaaaacttt cttatcaaaa agaatctagc caaagaagcg
     6841 actgctcaag ctgtaggtga acttcgtggt aaacaaaaat cggaagaaaa agctcacgct
     6901 gagatgattg cagaaggaaa agcaattaaa gcacaacttg aagcagaaga aactgttgta
     6961 gaatttgttg aaaaagttgg tccagatggt cgtacctttg gttctattac caataagaag
     7021 attgcagaag aattgcaaaa gcaatttgga attaagattg ataaacgtca tattcaagta
     7081 caagctccga ttcgagcggt tggtttgatt gatgtgccag tgaaaatcta tcaagatatc
     7141 acaagtgtaa tcaatcttcg tgtgaaagaa ggataagttt acaccttctt gacaagattg
     7201 taaaaggaag ggaagtctga tggcagaagt agaagagtta cgagtacaac ctcaagatat
     7261 cttagctgag caatccgttt taggggctat ctttattgat gagagtaaac ttgtttttgt
     7321 gcgagaatac attgagtctc gggacttttt taagtatgcc catcgtttga ttttccaagc
     7381 catggtcgat ttatccgatc gtggtgatgc catagatgca acaacggttc gtactatcct
     7441 tgataatcaa ggtgatttac agaatattgg tggcttgtct tacttggttg agattgtcaa
     7501 ttctgtgcca acttctgcta atgcggagta ttatgctaag attgttgcag aaaaagcaat
     7561 gctacgtcgt ttaattgcca agttgacaga gtctgtcaac caagcttacg aagcgtcaca
     7621 accagctgat gaaattattg ctcaggcaga aaaagggctg attgatgtca gtgaaaatgc
     7681 aaatcgaagc gggtttaaga acattcgaga tgtgttgaat ctcaactttg gaaatctgga
     7741 agctcgctcg caacaaacga ccgatattac aggtattgcg acaggttatc gtgatttgga
     7801 tcatatgaca acaggacttc atgaggagga gttgattatc ttagcagctc gtccagcagt
     7861 tggtaagaca gcatttgcct tgaatatcgc tcagaatatt gggactaagt tggacaaaac
     7921 ggttgctatt ttttcactcg aaatgggtgc ggaaagcttg gtagaccgta tgttagctgc
     7981 agaaggcttg gtggagtcac attctatccg tacagggcaa ttgacagatg aggagtggca
     8041 aaaatatact attgctcagg gtaatctagc taacgccagt atctatatcg atgatacgcc
     8101 aggtattcgg attacagaga ttcgttctcg ttctcgtaaa ttggctcaag aaactggaaa
     8161 tcttggtttg attttgatag actatttgca acttatcacg ggaactggtc gagaaaatcg
     8221 tcaacaagaa gtttctgaaa tttctcgtca gttgaaaata ctagccaagg aattgaaggt
     8281 tccagtaatc gctctgagtc agctttctcg tggtgtagaa caacgtcagg acaagagacc
     8341 ggtcttgtct gatattcgtg aatctgggtc tattgagcag gacgctgata tcgtagcttt
     8401 tctctatcgc gatgactact atgaacgtgg tggtgaagaa gaggagggta tcccaaataa
     8461 taaggtggaa gttattatcg agaaaaaccg tagtggagct cgtggaacag tggaattgat
     8521 tttccaaaaa gaatacaata aattttcaag tatctcaaag agggaggcat aagatgtcag
     8581 atgcatttac agatgtagcc aagatgaaaa aaatcaaaga agaaattaag gcacatgagg
     8641 gacaagtcgt agaaatgact ttggagaatg gtcgtaagcg ccaaaaaaat agattgggta
     8701 agctaattga agtttatcca tccctattta ttgtggagtt tggggatgtg gaaggagata
     8761 aacaagttaa tgtttacgtt gaatccttta cttactcaga tattcttaca gaaaagaatt
     8821 tgattcatta tcttgactaa agtgagaaat tttctcactt tttctttttt ctccgaataa
     8881 tttaggtgaa ggcaatcatc gctttatatt attttttaag gaggaagaat gaaaatttta
     8941 ccgtttatag caagaggaac aagttattac ttgaagatgt cagttaaaaa gcttgttcct
     9001 tttttagtag taggattgat gctagcagct ggtgatagtg tctatgccta ttccagagga
     9061 aatggatcga ttgcgcgtgg ggatgattat cctgcttatt ataaaaatgg gagccaggag
     9121 attgatcagt ggcgcatgta ttctcgtcaa tgtacttctt ttgtagcctt tcgtttgagt
     9181 aatgtcaatg gttttgaaat tccggcagct tatggaaatg cgaatgaatg gggacatcgt
     9241 gctcgtcggg aaggttatcg tgtagataat acaccgacga ttggttccat tacttggtct
     9301 actgcaggaa cttatggtca tgttgcctgg gtgtcaaatg taatgggaga tcagattgag
     9361 attgaggaat ataactatgg ttatacagaa tcctataata aacgaattat aaaagcaaac
     9421 acgatgacag gatttattca ttttaaagat ttggatggtg gcagtgttgg gaatagtcaa
     9481 tcctcaactt caacaggcgg aactcattat tttaagacca agtctgctat taaaactgaa
     9541 cccctagtta gtgcaactgt gattgattac tattatcctg gagagaaggt tcattatgat
     9601 caaattctcg aaaaagacgg ctacaagtgg ttgagttata ctgcctataa tggaagctat
     9661 cgttatgttc aattggaggc tgtgaataaa aatcctctag gtaattctgt tctttcttca
     9721 acaggtggaa ctcattattt taagaccaag tctgctatca aaactgaacc cctagttagt
     9781 gcaactgtga ttgattacta ttatcctggg gagaaggttc attatgatca gatacttgaa
     9841 aaagacggct acaagtggtt gagttatacg gcttataacg gaagtcgtcg ctatatacag
     9901 ctagagggag tgacttcttc acaaaattat cagaatcaat caggaaatat ctctagctat
     9961 ggatccaata atagttcaac tgtcggttgg aagaaaataa atggtagttg gtatcatttc
    10021 aaatcaaatg gttctaaatc aacaggatgg ctgaaagatg gttctagctg gtattatttg
    10081 aaattatctg gtgaaatgca gacaggatgg ttaaaggaga atggctcgtg gtattatctg
    10141 ggtagttcag gggcaatgaa aacaggctgg taccaggtct ctggtaagtg gtattattct
    10201 tactcttcag gcgccttagc tgttaatacg acggtggatg gctacagagt aaacagtgat
    10261 ggagaacgag tatagaaaat tggagtagga gaaatttcct gctcttttct gtaagcagtt
    10321 tccttgacat tttttttatt ttgcgctatc atatatacat ataatatatg ggagtctgtg
    10381 tacagtctga gaggaagtgt taaacttcga ccgcacctga tctgggtaat gccagcggag
    10441 ggaacgatac ttagtctaat tttgtacctt ttccatgtat ggtaaaggtt tttctttttt
    10501 ttaaaaggaa aacgagaaga ggaggttctt atgaaagcaa gcattgcctt gcaagtttta
    10561 cccctagtac aggggattga tcggatagct gttattgatc aggtcattgc ttatctgcaa
    10621 actcaagaag tgccgatggt agtgacacca tttgaaacgg tcttggaagg ggagtttgat
    10681 gagcttatgc gcattctaaa agaagcgctg gaagtggcag ggcaggaggc agacaatgtc
    10741 tttgccaatg tcaaaataaa tgtaggagag attttaagta ttgatgagaa acttgagaag
    10801 tatactgaga cgacacatta gtctattggg ctttctcgga gtcttgtcaa tctggcagtt
    10861 agcaggtttt cttaaactgc tccccaagtt tatcctgccg acacctcttg aaattctcca
    10921 gccctttgtt cgtgacagag aatttctctg gcaccatagc tgggcgacct tgagagtggc
    10981 tttactgggg ctgattttgg gagttttgat tgcctgtctt atggctgtac tcatggatag
    11041 tttgacttgg ctcaatgacc tgatttaccc tatgatggtg gtcattcaga ccattccgac
    11101 cattgccata gctcctatcc tggtcttgtg gctaggttat gggattttgc ccaagattgt
    11161 cttgattatc ttaacgacaa cctttcccat catcgttagt attttggacg gttttaggca
    11221 ttgtgacaag gatatgctga ccttgtttag tctgatgcga gccaagcctt ggcaaatcct
    11281 gtggcatttt aaaatcccgg ttagcctgcc ttacttttat gcaggtctga gggtcagtgt
    11341 ctcctacgcc tttatcacaa ctgtggtatc tgagtggttg ggaggttttg aaggtcttgg
    11401 tgtttatatg attcagtcta aaaaactgtt tcagtatgat accatgtttg ccattattat
    11461 tctggtgtcg attatcagtc ttttgggtat gaagctggtc gatatcagtg aaaaatatgt
    11521 gattaaatgg aaacgttcgt agaattagaa tgtttctgaa aaagaaaaga ggaaatcaaa
    11581 atgaagaaaa catggaaagt gtttttaacg cttgtaacag ctcttgtagc tgttgtgctt
    11641 gtggcctgtg gtcaaggaac tgcttctaaa gacaacaaag aggcagaact taagaaggtt
    11701 gactttatcc tagactggac accaaatacc aaccacacag ggctttatgt tgccaaggaa
    11761 aaaggttatt tcaaagaagc tggagtggat gttgatttga aattgccacc agaagaaagt
    11821 tcttctgact tggttatcaa cggaaaggca ccatttgcag tgtatttcca agactacatg
    11881 gctaagaaat tggaaaaagg agcaggaatc actgccgttg cagctattgt tgaacacaat
    11941 acatcaggaa tcatctctcg taaatctgat aatgtaagca gtccaaaaga cttggttggt
    12001 aagaaatatg ggacatggaa tgacccaact gaacttgcta tgttgaaaac cttggtagaa
    12061 tctcaaggtg gagactttga gaaggttgaa aaagtaccaa ataacgactc aaactcaatc
    12121 acaccgattg ccaatggcgt ctttgatact gcttggattt actacggttg ggatggtatc
    12181 cttgctaaat ctcaaggtgt agatgctaac ttcatgtact tgaaagacta tgtcaaggag
    12241 tttgactact attcaccagt tatcatcgca aacaacgact atctgaaaga taacaaagaa
    12301 gaagctcgca aagtcatcca agccatcaaa aaaggctacc aatatgccat ggaacatcca
    12361 gaagaagctg cagatattct catcaagaat gcacctgaac tcaaggaaaa acgtgacttt
    12421 gtcatcgaat ctcaaaaata cttgtcaaaa gaatacgcaa gcgacaagga aaaatggggt
    12481 caatttgacg cagctcgctg gaatgctttc tacaaatggg ataaagaaaa tggtatcctt
    12541 aaagaagact tgacagacaa aggcttcacc aacgaatttg tgaaataatg acagaaatta
    12601 gactagagca cgtcagttat gcctatggtc aggagaggat tttagaggat atcaacctac
    12661 aggtgacttc aggcgaagtg gtttccatcc taggcccaag tggtgttgga aagaccaccc
    12721 tctttaatct aatcgctggg attttagaag ttcagtcagg gagaattgtc cttgatggtg
    12781 aagaaaatcc caaggggcgc gtgagttata tgttgcaaaa ggatctgctc ttggagcaca
    12841 agacggtgct tggaaatatc attctgcccc tcttgattca aaaggtggat aaggcagaag
    12901 ctatttcccg cgcggataaa attcttgcga ccttccagct gacagctgta agagacaagt
    12961 atcctcatga acttagcggt gggatgcgcc agcgtgtagc cttactccgg acctaccttt
    13021 ttgggcacaa gctctttctc ttagatgagg cctttagcgc cttggatgag atgacaaaga
    13081 tggaactcca cgcttggtat cttgagattc acaagcagtt gcagctaaca accctgatca
    13141 tcacgcatag tattgaggag gccctcaatc tcagcgaccg catctatatc ttgaaaaatc
    13201 gccctgggca gattgtttca gaaattaaac tagattggtc tgaagatgag gacaaggaag
    13261 tccaaaagat tgcctacaaa cgtcaaatct tggcagaatt aggcttagat aagtagaaaa
    13321 atagggagtt ggtgaagatt atcctttacc agcgcccttt ttcttttaaa aatgagaaaa
    13381 tttcggtata atagtcaaac aaggtcaagg tttaaagaga gaggtgggtt tgttatgaga
    13441 tttaaaaata catcggatca tattgaggcc tacatcaagg cgattttaga tcaatctggt
    13501 atcgtggagt tgcaacggag tcagttggca gatacctttc aggttgttcc tagtcagatt
    13561 aactacgtga tcaagacacg ctttacggaa agtagaggct acttggttga aagtaagcgt
    13621 ggtggcggag gctacattcg tataggacgg attgagtttt ctagtcatca tgaaatgctc
    13681 cgggagctgc tttactcgat tggtgagcga gtcagtcaag aaatttatga ggatattctc
    13741 cagcttttgg ttgagcagga attgatgacc aagcaggaga tgaatttgct agaatcagta
    13801 gctttggatc gcgttttagg agaagaagct ccagttgttc gagcaaacat gctacgtcag
    13861 gtcatacaag aggtagatag aaaagggagg taagatgaac tattcaaaag cattgaatga
    13921 atgtatcgaa agtgcctaca tggttgctgg acattttgga gctcgttatc tagagtcttg
    13981 gcacttgttg attgccatgt ctaatcacag ttatagtgta gcaggggcaa ctttaaatga
    14041 ttatccgtat gagatggacc gtttagaaga ggtggctttg gaactgactg aaacggacta
    14101 tagccaggat gaaaccttta cggaattgcc gttctcccgt cgtttgcagg ttctttttga
    14161 tgaagcagag tatgtagcgt cagtggtcca tgctaaggta ctagggacag agcacgtcct
    14221 ctatgcgatt ttgcatgatg gcaatgcctt ggcgactcgt atcttggaga gggctggttt
    14281 ttcttatgaa gacaagaaag atcaggtcaa gattgctgct cttcgtcgaa atttagaaga
    14341 acgggcaggc tggactcgtg aagatctcaa ggctttacgc caacgccatc gtacagtagc
    14401 tgacaagcaa aattctatgg ccaatatgat gggcatgccg cagactccga gtggtggtct
    14461 cgaggattat acgcatgatt tgacagagca agcgcgttct ggcaagttag aaccagtcat
    14521 cggtcgggac aaggaaatct cacgtatgat tcaaatcttg agccgtaaga ctaagaacaa
    14581 ccctgtcttg gttggggatg ctggtgtcgg gaaaacagct ctggcccttg gtcttgccca
    14641 gcgtattgct agtggtgacg tgcctgcgga aatggctaag atgcgcgtgt tagaacttga
    14701 tttgatgaat gtcgttgcag ggacacgctt ccgtggtgac tttgaagaac gcatgaataa
    14761 tatcatcaag gatattgaag aagatggcca agtcatcctc tttatcgatg aactccacac
    14821 catcatgggt tctggtagcg ggattgattc gactctggat gcggccaata tcttgaaacc
    14881 agccttggcg cgtggaactt tgagaacggt tggtgccact actcaggaag aatatcaaaa
    14941 acatatcgaa aaagatgcgg cactttctcg tcgtttcgct aaagtgacga ttgaagaacc
    15001 aagtgtggca gatagtatga ctattttaca aggtttgaag gcgacttatg agaaacatca
    15061 ccgtgtacaa atcacagatg aagcggttga aacagcggtt aagatggctc atcgttattt
    15121 aaccagtcgt cacttgccag actctgctat cgacctcttg gacgaagcag cagcaacagt
    15181 gcaaaataag gcaaatcatg taaaagcaga cgattcagat ttgagtccag ctgacaaggc
    15241 cctgatggat ggcaagtgga aacaggcagc ccagctaatc gcaaaagaag aggaagtacc
    15301 tgtctacaaa gacttggtga cagagtctga tattttgacc accttgagtc gcttgtcagg
    15361 aatcccagtt caaaaactga ctcagactga cgctaagaaa tatctaaatc ttgaagcaga
    15421 actccataaa cgggttatcg gtcaagatca agctgtttca agtattagtc gtgcgattcg
    15481 ccgtaatcag tcaggaattc gcagtcacaa gcgtccgatc ggttccttta tgttcctagg
    15541 acccacaggt gtcggtaaga ccgagttggc caaggctttg gcagaagttc tctttgatga
    15601 cgaatcagcc cttatccgct ttgatatgag tgagtatatg gagaaattcg cagccagccg
    15661 tctaaatgga gctcctccag gctatgtggg ttacgaagaa ggtggggagt tgacagagaa
    15721 ggttcgcaat aaaccctatt ccgttctcct ctttgatgag gtagagaagg ctcacccaga
    15781 tatctttaat gttctcttgc aggttctgga tgacggtgtc ttgacagata gcaagggacg
    15841 caaggtcgat ttttcaaata ccattatcat tatgacatcg aacctaggtg cgactgccct
    15901 tcgtgatgat aagactgttg gttttggggc taaggatatt cgttttgacc aggaaaatat
    15961 ggaaaaacgc atgtttgaag aactgaaaaa agcttataga ccggaattca tcaaccgtat
    16021 tgatgagaag gtggtcttcc atagcctatc tagtgaccat atgcaggaag tggtgaagat
    16081 tatggtcaag cctttagtgg caagtttggc tgaaaaaggc attgacttga aattacaagc
    16141 ttcagctctg aaattgttag caaatcaagg atatgaccca gagatgggag ctcgcccact
    16201 tcgcagaacc ctgcaaacag aagtggagga caagttggca gaacttcttc tcaagggaga
    16261 tttagtggca ggcagcacac ttaagattgg tgtcaaagca ggccagttaa aatttgatat
    16321 tgcataaaag aataaaagta ccagcatctg accataagtc acagtggagt gaaactcaat
    16381 gaaaatcaaa gagcaaacta ggcagctagc cgcaggttgc tcaaaacact ggtttgaggt
    16441 tgcagataga gctgacgtgg tttaaagaga tttttgaaga gtataagctg caagatgaat
    16501 gattttcttg tattgacgtt gttgttgaca aaaagtagcg gataaatgaa atccattcca
    16561 ttatcataga tgataggctg gtaggaaatt ttcaaatagc atacagaaaa tagatgtatg
    16621 gagttctggt agtagaaagg gagagagatg aacattttag ttgcagatga cgaggaaatg
    16681 attagagaag gaattgcagc atttctgaca gaagagggtt atcatgtcat tatggctaag
    16741 gatggacaag aggtcttgga aaaatttcaa gatctcccta tccatctcat ggtactggat
    16801 ttaatgatgc ctaggaagag tggttttgaa gtgttaaaag aaatcaatca aaagcacgat
    16861 attcctgtca tcgtcttgag tgctctggga gatgaaacta ctcagtcaca ggtatttgat
    16921 ctctatgctg atgatcatgt gacaaaacct ttttctttgg tactgcttgt caagcgtatt
    16981 aaggcgctta tcagacgtta ctacgtcata gaggatattt ggcgatatca ggatgtaaca
    17041 gtggatttta cctcttacaa agcacattat aaaaatgaag aaattgatct caaaccaaag
    17101 gaattactgg tactaaagtg tttgattcag cataaaaatc aagttttaag tagagagcag
    17161 atattggaag aaatttcaaa agatgtagct gatttacctt gtgatagggt cgttgatgtc
    17221 tatattcgta ctcttcgcaa aaaattagct ttagattgta tcgtgactgt gaaaaatgtt
    17281 gggtataaga ttagcttatg ataaaaaatc ctaaattatt aaccaagtct tttttaagaa
    17341 gttttgcaat tctaggtggt gttggtctag tcattcatat agctatttat ttgacctttc
    17401 ctttttatta tattcaactg gagggggaaa agtttaatga gagcgcaaga gtgtttacgg
    17461 agtatttaaa gactaagaca tctgatgaaa ttccaagctt actccagtct tattcaaagt
    17521 ccttgaccat atctgctcac cttaaaagag atattgtaga taagcggctc cctcttgtgc
    17581 atgacttgga tattaaagat ggaaagctat caaattatat cgtgatgtta gatatgtctg
    17641 ttagtacagc agatggtaaa caggtaaccg tgcaatttgt tcacggggta gatgtctaca
    17701 aagaagcaaa gaatattttg cttttgtatc tcccatatac atttttggtt acaattgctt
    17761 tttcctttgt tttttcttat ttttatacta aacgcttgct caatcctctt ttttacattt
    17821 cagaagtgac tagtaaaatg caagatttgg atgacaatat tcgttttgat gaaagtagga
    17881 aagatgaagt tggtgaagtt ggaaaacaga ttaatggtat gtatgagcac ttgttgaagg
    17941 ttattcatga gttggaaagt cgtaatgagc aaattgtaaa attgcaaaat caaaaggttt
    18001 cctttgtccg cggagcatca catgagttga aaaccccttt agccagtctt agaattatcc
    18061 tagagaatat gcagcataat attggagatt acaaagatca tccaaaatat attgcaaaga
    18121 gtataaataa gattgaccag atgagccact tattggaaga agtactggag tcttctaaat
    18181 tccaagagtg gacagagtgt cgtgagacct tgactgttaa gccagtttta gtagatattt
    18241 tatcacgtta tcaagaatta gctcattcaa taggtgttac aattgaaaat caattgacag
    18301 atgctaccag ggtcgtcatg agtcttaggg cattggataa ggttttgaca aacctgatta
    18361 gtaatgcaat taaatattca gataaaaatg ggcgcgtaat catatccgag caagatggct
    18421 atctctctat caaaaataca tgtgcgcctc taagtgacca agaactagaa catttatttg
    18481 atatattcta tcattctcaa atcgtgacag ataaggatga aagttccggt ttgggtcttt
    18541 acattgtgaa taatatttta gaaagctatc aaatggacta tagttttctc ccttatgaac
    18601 acggtatgga atttaagatt agcttgtaga cagattagtt ttttattaaa gttcatatag
    18661 ggttaacata agtgtgttat tctttgtgta gataaaagaa aggatactaa tatggtatta
    18721 gcgattattt tagtaacatt ccttattcga ttgatttttt taaagcgttc gatagagaat
    18781 gagaaacgaa tccttagcaa tggcgggaaa gaatttggag ttgagaatac aaaacgatta
    18841 actatggctc atattgtttt ttatctctct tgcttggttg aggcaatggt gcacaagaca
    18901 atttttgatg gcatgggcat ggttggttta gtcttgctta ttttttctat gctgatgttg
    18961 atgttggtga ttcacttgtt gggagatatt tggacagtga agcttatgct tgtcaataat
    19021 cacaaatatg tagatcatat cttgtttagg acagtaaaac atcctaatta ctttttaaat
    19081 attcttcctg agttgattgg cttgaccttg ttgagtcatg cttatgtgac ttttgtttta
    19141 gtttttccag tttatgcagt tattttgtat cgacgaatag ctgaagagga aaagctatta
    19201 catgaagtta taatcccaaa tggaagcata aagagataaa tacaaaattc gatttatata
    19261 cagttcatat tgaagtgata tagtaaggtt aaagaaaaaa tataggagat aattatgttt
    19321 gcatcaaaaa gcgaaagaaa agtacattat tcaattcgta aatttagtat tggagtagct
    19381 agtgtagctg ttgccagtct ttttatggga agtgtggttc atgcgacaga gaaggaggta
    19441 actacccaag tagccacttc ttctaataag gcaaataaaa gtcagacaga acatatgaaa
    19501 gctgctgaac aaggaaaaca acatagagaa atcgatttag accgaaataa ggcaaagaaa
    19561 gcgatcgatg aatatataga aaaaatgttg agtgagatcc aattagataa aagaaaacat
    19621 acccaaaatt tcgccttaaa cataaagttg agcagaatta aaacggagta tttgtatgga
    19681 ttaagtgttt taaaagagaa gtcggaagct gagttgccgt caaaaataaa agaaaagtta
    19741 accgcagctt ttgagcagtt taaaaaagat acattgaaac caggagaaaa ggtagcagaa
    19801 gctaagaaga aggttgaaga agctgagaaa aaagccaagg atcaaaaaga agaagatcgt
    19861 cgtaactacc caaccattac ttacaaaacg cttgaacttg aaattgctga gtccgatgtg
    19921 gaagttaaaa aagcggagct tgaactagta aaagaggaag ctaacaaacc tcgaaacgag
    19981 caaaaagtta agcaagcaaa agcgaaagtt gagagtaaac aagctgaggc tacaaggtta
    20041 aaaaaaatca agacagatcg tgaagaagca gaagaagaag ctaaacgaag agcagaagct
    20101 aagttgaagg aagctgttga aaagaataca gcgacttcag agcaaggtaa accaaagagg
    20161 cggggaaaac gaggagctct tggagagcaa gcaacacctg ataaaaaaga aaatgatgcg
    20221 aagtcttcag attctagcgt aggtgaagaa actcttccaa gcccatccct gaaaccagaa
    20281 aaaaaggtag cagaagctca gaagaaggtt gcagaagctg agaaaaaagc caaggatcaa
    20341 aaagaagaag atcgccgtaa ctacccaacc aatacttaca aaacgcttga acttgaaatt
    20401 gctgagtccg atgtgaaagt taaagaagcg gagcttgaac tagtaaaaga ggaagctaag
    20461 gaatctcgaa acgaggaaaa aattaagcaa gtaaaagcga aagttgagag taaacaagct
    20521 gaggctacaa ggctagaaaa catcaagaca gatcgtaaaa aagcagaaga agaagctaaa
    20581 cgaaaagcag cagaagaaga taaagttaaa gaaaaaccag ctccagcacc acaaccagcg
    20641 ccggctcctc aaccagaaaa accaactgaa gagcctgaga
//
LOCUS       DAVLHB010000037        20672 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLHB010000037 DAVLHB010000000
VERSION     DAVLHB010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.037"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            149..2131
                     /locus_tag="VXE36_001496"
     CDS             149..2131
                     /locus_tag="VXE36_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779786.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2432..7744
                     /locus_tag="VXE36_001497"
     CDS             2432..7744
                     /locus_tag="VXE36_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0779787.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVAAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLPTDKEKMYYFNTQTGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTRYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKVKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPIVEKPEFKLRSLASVQGKTPDYKQEID
                     RPDRPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7911..10070)
                     /locus_tag="VXE36_001498"
     CDS             complement(7911..10070)
                     /locus_tag="VXE36_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0779788.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10067..10663)
                     /gene="recU"
                     /locus_tag="VXE36_001499"
     CDS             complement(10067..10663)
                     /gene="recU"
                     /locus_tag="VXE36_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0779789.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10729..11256
                     /locus_tag="VXE36_001500"
     CDS             10729..11256
                     /locus_tag="VXE36_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0779790.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11326..11655
                     /gene="gpsB"
                     /locus_tag="VXE36_001501"
     CDS             11326..11655
                     /gene="gpsB"
                     /locus_tag="VXE36_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0779791.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11676..12056
                     /gene="rnpB"
                     /locus_tag="VXE36_001502"
     ncRNA           11676..12056
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXE36_001502"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12141..13298
                     /locus_tag="VXE36_001503"
     CDS             12141..13298
                     /locus_tag="VXE36_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0779792.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQNLRSDKINGVIISNPPYGERLSDDAGVTKLYTEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13311..14705
                     /gene="mapZ"
                     /locus_tag="VXE36_001504"
     CDS             13311..14705
                     /gene="mapZ"
                     /locus_tag="VXE36_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0779793.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTVNQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14781..16205
                     /gene="gndA"
                     /locus_tag="VXE36_001505"
     CDS             14781..16205
                     /gene="gndA"
                     /locus_tag="VXE36_001505"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0779794.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16217..16906
                     /locus_tag="VXE36_001506"
     CDS             16217..16906
                     /locus_tag="VXE36_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0779795.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17004..18023
                     /gene="cbpC"
                     /locus_tag="VXE36_001507"
     CDS             17004..18023
                     /gene="cbpC"
                     /locus_tag="VXE36_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0779796.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNLLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18141..19373)
                     /locus_tag="VXE36_001508"
     CDS             complement(18141..19373)
                     /locus_tag="VXE36_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0779797.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19903..20378)
                     /locus_tag="VXE36_001509"
                     /pseudo
     CDS             complement(19903..20378)
                     /locus_tag="VXE36_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
BASE COUNT         6444 a         3721 c         4628 g         5879 t
ORIGIN      
        1 atatacttcg ttattgggcg cttacaatga tattcatatt ttttgcaaag atgttgtttg
       61 aaaaataatt ttcaaaaatt ctgaaaattc tgttgacaac tttctgaaaa gagtctataa
      121 tggagagaaa gttttaaagg agaaaatgat gaaaagttca aaactatttg cccttgcggg
      181 cgtgacatta ttggcggcga ctactttagc tgcatgctct ggatcaggtt caagtactaa
      241 aggtgagaag acattctcat acatttatga gacagaccct gataacctca actatttgac
      301 aactgctaag gctgcgacag caaatattac cagtaacgtg gttgatggtt tgctagaaaa
      361 tgatcgctac gggaactttg tgccgtctat ggctgaggat tggtctgtat ccaaggatgg
      421 attgacttac acttatacta tccgtaagga tgcaaaatgg tatacttctg aaggtgaaga
      481 atacgcggca gtcaaagctc aagactttgt aacaggacta aaatatgctg ctgataaaaa
      541 atcagatgct ctttaccttg ttcaagaatc aatcaaaggg ttggatgcct atgtaaaagg
      601 ggaaatcaaa gatttctcac aagtaggaat taaggctctg gatgaacaga cagttcagta
      661 cactttgaac aaaccagaaa gcttctggaa ttctaagaca accatgggtg tgcttgcgcc
      721 agttaatgaa gagtttttga attcaaaagg ggatgatttt gccaaagcta cggatccaag
      781 tagtctcttg tataacggtc cttatttgtt gaaatccatt gtgaccaaat cttctgttga
      841 atttgcgaaa aatccgaact actgggataa ggacaatgtg catattgaca aagttaaatt
      901 gtcattctgg gatggtcaag ataccagcaa acctgcagaa aactttaaag atggtagcct
      961 tacagcagct cgtctctatc caacaagtgc aagtttcgca gagcttgaga agagtatgaa
     1021 ggacaatatt gtctatactc aacaagactc tattacgtat ctagttggta caaatattga
     1081 ccgtcagtcc tataaataca catctaagac cagcgatgaa caaaaggcat cgactaaaaa
     1141 ggctctctta aacaaggatt tccgtcaggc tattgccttt ggttttgatc gtacagccta
     1201 tgcctctcag ttgaatggac aaactggagc aagcaaaatc ttacgtaata tctttgttcc
     1261 accaacattt gttcaagcag atggtaaaaa ctttggcgat atggtcaaag agaaattggt
     1321 cacttatggg gatgaatgga aggatgttaa tcttgcagat tctcaggatg gtctttacaa
     1381 tccagaaaaa gccaaggctg aatttgctaa agctaaatca gccttacaag cagaaggtgt
     1441 gacattccca attcatttgg atatgccagt tgaccaaaca gcaactacaa aagttcagcg
     1501 cgtccaatct atgaaacaat ccttggaagc aactttagga gctgataatg tcattattga
     1561 tatccaacaa ctacaaaaag acgaagtaaa caatattaca tattttgctg aaaatgctgc
     1621 tggcgaagac tgggatttat cagataatgt cggttggggt ccagactttg ccgatccatc
     1681 aacctacctt gatatcatca aaccatctgt aggagaaagt actaaaacat atttagggtt
     1741 tgactcaggg gaagataatg tagctgctaa aaaagtaggt ctatatgact acgaaaaatt
     1801 ggttactgag gctggtgatg aggctacaga tgttgctaaa cgctatgata aatacgctgc
     1861 agcccaagct tggttgacag atagtgcttt gattattcca actacatctc gtacagggcg
     1921 tccaattttg tctaagatgg taccatttac aataccattt gcattgtcag gaaataaagg
     1981 tacaagtgaa ccagtcttgt ataaatactt ggaacttcaa gacaaggcag tcactgtaga
     2041 tgaataccaa aaagctcagg aaaaatggat gaaagaaaaa gaagagtcta ataaaaaggc
     2101 tcaagaagat ctcgcaaaac atgtgaaata actgttgcaa aatataagaa aggatttagt
     2161 atttctcttg aatgctgaat ccttttttac atttgtaaag aaagattcta aatgtactga
     2221 cccccaaaag ttggagcctc tttttgtcag aatagagaaa atttttgtta attttacttg
     2281 tttcctattg ctttctcagc tattatttgt tatattaaaa gtataattat tttttattta
     2341 tcagggttaa gcattgcact ttcagaggaa ggagtatttt ttaaaaagaa aatgtaaacg
     2401 cttgctcaaa aatgaaagga tttagaagtt tatgaataaa ggattatttg aaaaacgttg
     2461 taaatatagt attcggaaat tttcattagg tgttgcttct gttatgattg gagctgcatt
     2521 ctttgggaca agtccggttc ttgcagatag cgtgcagtct ggttccacgg cgaacttacc
     2581 agctgattta gctactgctc ttgcaacagc aaaagagaat gatgggcgtg attttgaagc
     2641 gcctaaggtg ggagaagacc aaggttctcc agaagttaca gatggaccta agacagaaga
     2701 agaactatta gcacttgaaa aagaaaaacc ggctgaagaa aaaccaaaag aggataaacc
     2761 tgcagctgct aaacctgaaa cacctaagac ggtaacccct gaatggcaga cggtagagaa
     2821 aaaagaacaa aagggaacag tcactatccg agaagaaaaa ggtgtccgct acaaccaact
     2881 atcctcaact gctcaaaatg ataacgcagg taaaccagcc ctgtttgaaa agaagggctt
     2941 gaccgttgat gccaatggaa atgcaactgt tgatttaacc ttcaaagaag attctgaaaa
     3001 gggcaaatca cgctttggtg tcttcctgaa atttaaagat accaagaaca atgtttttgt
     3061 cggttatgac aaggatggct ggttctggga atacaaaact ccaggtaata gcacatggta
     3121 taaaggcaac cgtgtagctg caccagaacc gggttctgta aaccgtcttt ctatcactct
     3181 caagtcagat ggacaactca atgccagcaa caacgatgtc aatctctttg acacagtgac
     3241 tctaccagct gcggtcaatg accatcttaa aaatgagaag aagatccttc tcaaggcagg
     3301 aacttatggc aatgaccgta cggttgtcag cgttaaaaca gacaatcaag aaggcgtaaa
     3361 agcggatgat actcctgccc agaaagaaac aggtccggtt gttgacgata gcaaggtgac
     3421 ttatgatacg atccagtcta aggtcctcaa agcagtgatt gaccaagcct tccctcgtgt
     3481 caaggaatac accttgaacg ggcatacttt gccaggacaa gtgcaacagt tcaaccaagt
     3541 ctttatcaat aaccaccgaa tcacccctga agtcacttat aagaaaatca atgagacaac
     3601 agcagagtac ttgatgaagc ttcgcgatga tgctcactta atcaatgcgg aaatgacagt
     3661 acgcttgcaa gttgtggaca atcaattgca ctttgatgtg accaagattg tcaaccacaa
     3721 tcaagtcact ccaggtcaaa agatcgatga cgaaagaaaa ctactttctt ctattagttt
     3781 cctcggcaat gctttagtct ctgtttctag tgatcaaact ggtgctaagt ttgatggggc
     3841 aaccatgtca aacaatacgc atgtcagcgg agatgatcat atcgatgtaa ctaatccaat
     3901 gaaggatttg gctaagggtt acatgtatgg atttgtttct acagataagc ttgctgctgg
     3961 tgtttggagt aactctcaaa atagctatgg tggtggttcg aatgactgga ctcgtttgac
     4021 agcttataaa gaaacagtcg gaaatgccaa ctatgtagga atccacagct ctgaatggca
     4081 atgggaaaaa gcttataagg gcattgtttt cccagaatac acgaaggaac ttccaagtgc
     4141 taaggttgtt atcactgaag atgccaatgc agacaagaaa gtcgattggc aagatggtgc
     4201 cattgcttat cgtagcatta tgaacaaccc tcaaggttgg gaaaaagtta aggatatcac
     4261 agcttaccgt atcgcgatga actttggttc tcaagcacaa aacccattcc ttatgacctt
     4321 ggatggtatc aagaaaatca atctccacac agatggtctt gggcaaggtg ttctccttaa
     4381 aggatatggt agcgaaggtc atgactctgg tcacttgaac tatgctgata ttggtaagcg
     4441 tatcggtggt gtcgaagact tcaagaccct aattgagaag gctaagaaat atggagctca
     4501 tctaggtatc cacgttaacg cttcagaaac ttatcctgag tctaaatact tcaatgaaaa
     4561 aattctccgt aagaatccag atggaagcta tagctatggt tggaactggc tagatcaagg
     4621 tatcaacatt gatgctgcct atgacctagc tcatggtcgt ttggcacgtt gggaagattt
     4681 gaagaaaaaa cttggtgacg gtctcgactt tatctatgtg gacgtttggg gtaatggtca
     4741 atcaggtgat aacggtgcct gggctaccca cgttcttgct aaagaaatta acaaacaagg
     4801 ctggcgcttt gcgatcgagt ggggccatgg tggtgagtac gactctacct tccatcactg
     4861 ggcagctgac ttgacctacg gtggctacac caataaaggt atcaacagtg ccatcacccg
     4921 ctttatccgt aaccaccaaa aagatgcttg ggttggggac tacagaagtt atggtggtgc
     4981 agccaactat ccactgctag gtggctacag catgaaagac tttgaaggct ggcaaggaag
     5041 aagtgattac aatggctatg taaccaactt atttgcccat gacgtcatga ctaagtactt
     5101 ccaacacttc actgtaagta aatgggaaaa tggtacaccg gtgactatga ccgataacgg
     5161 tagcacctat aaatggactc cagaaatgcg agtggaattg gtagatgctg acaataataa
     5221 agtagttgta actcgtaagt caaatgatgt caatagccca caatatcgcg aacgtacagt
     5281 aactctcaac ggacgtgtca tccaagatgg ttcagcttac ttgactcctt ggaactggga
     5341 tgcgaatggt aagaaacttc ctactgataa ggaaaagatg tactacttca atacgcagac
     5401 tggtgcaaca acttggaccc ttccaagcga ttgggcaaag agcaaggttt acctttacaa
     5461 gctaactgac caaggtaaga cagaagagca agaactaact gtaaaagatg gtaaaattac
     5521 cctagatctt ctagcaaatc aaccatacgt tctctatcgt tcgaaacaaa ccaatcctga
     5581 aatgtcatgg agtgaaggca tgcacatcta tgatcaagga tttaatagcg gtactttgaa
     5641 acattggacc atttcaggcg atgcttctaa ggcagaaatt gtcaagtctc aaggggcaaa
     5701 cgatatgctt cgtattcaag gaaacaaaga aaaagttagt ctcactcaga aattaactgg
     5761 cttgaaacca aataccaggt atgccgttta tgttggtgta gataaccgta gtaatgccaa
     5821 ggcaagtatc actgtgaata ctggtgaaaa agaagtgact acttatacca ataagtctct
     5881 cgcgctcaac tatgttaagg cttacgccca caatacacgt cgtgacaatg ctacagttaa
     5941 cgatacaagt tacttccaaa acatgtacgc cttctttaca acaggatcgg acgtctcaaa
     6001 tgttactctg acattgagtc gtgaagctgg tgatcaagca acttactttg atgaaattcg
     6061 tacctttgaa aacaattcaa gcatgtatgg agacaagcat gatacaggta aaggcacctt
     6121 caagcaagac tttgaaaatg ttgctcaggg tatcttccca tttgtagtgg gtggtgtcga
     6181 aggtgtcgaa gacaaccgca ctcacttgtc tgaaaaacac gatccatata cacaacgtgg
     6241 ttggaatggt aagaaagtcg atgatgttat cgaaggaaat tggtcactca agacaaatgg
     6301 actagtgagc cgtcgtaact tggtttacca aaccatccca caaaacttcc gttttgaagc
     6361 aggtaagacc taccgtgtaa cctttgaata cgaagcaggt tcagacaata cctatgcttt
     6421 tgtagtcggt aagggagaat tccagtcagg tcgtcgtggt actcaagcaa gcaacttgga
     6481 aatgcatgaa ttgccaaata cttggacaga ttctaagaaa gccaagaagg taaccttcct
     6541 cgtgacaggt gcagaaacag gagatacttg ggtaggtatc tactcaactg gaaatgcaag
     6601 taatactcgt ggtgattctg gtggaaatgc caacttccgt ggttataacg acttcatgat
     6661 ggataatctt caaatcgaag aaattaccct aacaggtaag atgttgacag aaaatgctct
     6721 gaagaactac ttgccaacgg ttgccatgac taactacacc aaagagtcta tggatgcttt
     6781 gaaagaggcg gtctttaatc tcagtcaggc cgatgatgat atcagtgtgg aagaagcgcg
     6841 tgcagagatt gccaagattg aagccttgaa gaatgctttg gttcagaaga aaacggcttt
     6901 ggtagcagat gactttgaaa gtttggatgc gccagctcaa ccaggtgaag gtcttgagaa
     6961 tgcctttgat ggcaatgtgt ctagtctatg gcatacatct tggaatggtg gagatgtagg
     7021 caagcctgca accatggtct tgaaagaacc aactgaaatc actggacttc gttatgttcc
     7081 acgtggatca ggttcaaatg gtaacttgcg tgatgtgaaa cttgttgtga cagatgagtc
     7141 tggcaaggag cataccttta ctgcaactga ttggccagat aacaataagc caaaagacat
     7201 tgactttggt aagacaatta aggttaagaa aattgtcctt acaggtacta agacttacgg
     7261 agatggtggc gataaatacc aatctgcagc ggaacttatc tttactcgtc cacaggtagc
     7321 agaaacacct cttgacttgt caggctatga agcagctttg gctaaggctc agaaattaac
     7381 agacaaagac aatcaagagg aagtagctag cgttcaggca agcatgaaat atgcgacgga
     7441 taaccatctc ttgacggaaa gaatggtgga atactttgca gattatctca accaattaaa
     7501 agattctgct acgaaaccag atgctccaat tgtagagaaa cctgagttta aacttagatc
     7561 tttagcttcc gttcaaggta agacgccaga ttataagcaa gaaatagata gaccagatag
     7621 accagaaaca cctgaacaaa tcttgccagc aacaggtgag agtcaatctg acacagccct
     7681 cttcctagca ggtgttagcc tagccctatc tgctctcttt gtagtaaaaa cgaagaaaga
     7741 ctagtattta gtaaaacctc ttaacaagat tacggaagca gtctctatct tttccaatga
     7801 ggtttatagt acagaaaaag cctgagaaga tgtcttctca ggcttttgtt aagcacataa
     7861 atacaatagt gctatgacaa aatcacccag aaaaatctgg gtgataaatg ttatggttgt
     7921 gctggttgag gattctgatt ttgttgatca ggggttgtat ttgattgttg cgtattattg
     7981 ttaggattgg tagtcgtact attatttgtg cttggagtgg ttgagctaga ctgtgaagtt
     8041 gaactatctg atgatgagct tgaactttca gttgatgggg gttgttgtgg agcaggtgag
     8101 ttccacgtag aacgagcacc atttttaaat acgaattctc catttctgta gagcccctct
     8161 ggtatattcc aatcctctgg attgcttcct tcagacaggt aggtcatcat agagcggtaa
     8221 actttggcag cgaccgtaag gccattgcct acaagtggtg tcagacggtt agaatagcct
     8281 gtccatacag ccattgaata tttacgcgta tagccagcaa atagttcgtc aggtgctaca
     8341 aattgagagg tcttgatgtg gttttcaatt tcctcgtctg tatagttaga ggttcctgtt
     8401 ttaccagcct gagggagcca agcaagatag gcatttcgtc cagttccata actcaagact
     8461 gttttcatca tgtcggtcat catataggct gtcgtttcct tcatggcacg agttccgaca
     8521 ttagagaact ctttttcact cccatcacta aagacgactt tatggatata cattggttta
     8581 tagtaagttc caccatttgc aaaggcagcg taagcagcag ccatcttttc actacttgct
     8641 ccatattttt tgtctgattc ggttgtgtta cttgaaatgg catttgagta gtgaatactt
     8701 gggtagtcga ttcctagacc atttaggaaa gtcttggcgc ggttgagtcc gaccttgttt
     8761 agagtttcca cggctgggac gtttcgcgat tgttgcaggg cgtattgcaa ggtgatgttg
     8821 ccaaagtagc ccctatccca gttataaaca ggagtatttg tcccagggta gttatagggc
     8881 tcatcgtgaa cgatagtagc agttgaatcg tagacaccgt actccaaggc aggagcatag
     8941 tctgtgatcg gtttcatagt tgatccccag tcgcggtttg tttctactgc ttggttaatt
     9001 ccgaaggaaa cattacttga ctgatggcgt gctcctagct gggcaatgac tttaccgtta
     9061 gaaacatcaa caatggtaga agcgacttgc aattcatcgt ctggataggc aacgtattcg
     9121 tctgtattgt aaatatccca cagatgtttt tgagcttctt ggtctacatt tgtgtagaca
     9181 tccatcccag ttgtgagtag gttatagcct gtttcttctt caacttgatt gatgacttcc
     9241 ttgaggtaat tatccatgta agcagggtaa ttacttgctg atttgagact ttgtagccca
     9301 tcagtaattg gtgtattgac tgctttctca tactgttcag cagagatgta gccttgattt
     9361 ttcatttcag ataagaccaa gtttcggcgg tcttgggctg cttctggatg tgaatagggg
     9421 tcatattggt ttggtgcctg aggcattcca gccagcaagg ctaactgagg taaacttaaa
     9481 ttattgaggt ctttaccata gtagttttga gctgctgtct gcattccata gttcccatta
     9541 gacatgtaga ccttatttat atagtaggtc aagatttctt gcttggttgc tttttgttct
     9601 aactgaatcg ctaaccaagc ttcctgagcc ttacgagaaa tagtctggtc ggaagtcgaa
     9661 gttgaaaagt aagtcaactt aatcaactgt tgggtgagag ttgatccacc ttggagggaa
     9721 ttgctttgca gattgcgcaa gaaagctccc aggatacgga tggtatcaat ccccctgtgg
     9781 tcgaagaagc gatggtcttc gatagaaacg attgccttaa ccaaatctgt gggaatatca
     9841 ttagcttggg cattgacgcg gcgttcagaa cccaagtcag caatgagttg atttttattg
     9901 tcgtagattt tactagaagt tgttgcaact agtttactct cggataggct aggagccttg
     9961 ctaacgtagt agaaaaaaac tcctccgcct aagacaatgg ctgcgataac caagcttaag
    10021 aagctaatgc tcagatactt gattaggcgc agaatcgttg gtttgttcat cttgttttac
    10081 cacctaataa atgttctttg ataacattga gataaggaat ttgagggaag gcaccagcct
    10141 tgatttcata tccatattct cgaatatatt caagtggcat tgatttttgt cccttatctt
    10201 gatgatagaa gcgaatcaaa tcgaatgccg gcaataagta ggtttcttgc tgagaagaaa
    10261 agtgaagaag gacaaagcag attccttgtt gggcaaggac ttgttccata tgctgaatct
    10321 gatgtggatg aaaatttttc atcggaatcg cacgtttttg ttttgtttcc ttgacttcaa
    10381 agtcgatgta atatccatta taaacgccag aatagtccgt cgttgaagct tgtcgaaaat
    10441 aggcttcaac aatcttggca cgacttcgtt gtggatagtc cacttgtacg atttgaatag
    10501 gagttggttt cttatgtata acagccaagc cctgagacaa atagtagtcg ttggtagcat
    10561 tgatcatctt ttcaaaagac attcctcgat ttgcgaaatt tttgggttga gaaagagatg
    10621 tttgtctttt ttgtgatgaa actttatgtg gatagttgac cataattctc cttattggta
    10681 caataacatc actttattat accataattt gcacagaaag ggttaaaaat ggctacagct
    10741 ttggttttag gctattctgc ttttgatttg ggtttatttt ctgataagga tcctcgtctt
    10801 aaattgatta aaaaagcgat acgtaaagat ttagaggcta tggcagcaga tggggtgtct
    10861 tggcttgtgt ttacagggag tttgggtttt gaatattggg ttttagaggt tgctcaggag
    10921 atgaaaaccg aatacggttt ccagttggcc accatttttg cttttgaaac ccatggggaa
    10981 aattggaatg aaggcaatca gatgaaactg agtcgcttta agcaggtaga ctttgtcaaa
    11041 tatgcctatc ctcgctatga acacaagggg cagttaagag attatcagca gtttttgctg
    11101 gaaaacacga ctagttccta tcttttttat gatgaagaaa atgaaacaaa actagcttat
    11161 ttttaccaaa agatgaaaaa tcaagaggac tattttataa agagattaac atttgatcaa
    11221 ttaaatgaac ttgctgaaaa tttttccgaa aattgaagct ttgaccttga tttttgtttg
    11281 ccttttttta tataataata ctagcaagcg agaatggaga gagacatggc aagtattatt
    11341 ttttcagcga aagatatttt tgaacaagag tttggacgtg aagtccgtgg ctataataaa
    11401 gtagaagttg acgagttttt agacgatgtc atcaaggact atgaaaccta tgctgccttg
    11461 gtcaagtcac ttcgtcagga aattgcggat ttgaaggaag aattaactcg taaaccgaaa
    11521 ccttcaccag ttcaagcaga accccttgaa gcggcaatta caagttctat gacgaatttt
    11581 gatattttga aacgcctgaa tagattggaa aaagaagttt ttggtaaaca aattttagat
    11641 aactcagatt tttaagtagt tatttgagat gtgcaatttt tggataatcg cgtgaggaga
    11701 attgcttctc atgaggaaag tccatgctag cacaggctgt gatgcctgta gtgtttgtgc
    11761 taggcgaaac cataagccta gggacgagaa atcgttacgg cagttgaaat ggctaagtcc
    11821 ttggataagc cagagtaggc ttgaaagtgc cacagtgacg gagtctttct ggaaacagag
    11881 agagtggaac gcggtaaacc cctcaagcta gcaacccaaa ttttggtcgg ggcatggagt
    11941 acgcggaaac gaacgtagta ttctgactgc tatcagctag agctgttagt ggtagacaga
    12001 tgattatcga aggaagtggt cctagtcact tctggaacaa aacatggctt atagaaaatt
    12061 gcatataggt tggggctgag aaattttctc aacctcattt tttaaagtgg acatatagaa
    12121 aggtcttgca agactgtaac atgaaaaaag aatttaattt aattgcaact gtggcagcag
    12181 ggcttgaggc tgtcgttggt cgtgaagtgc gagagttggg ctacgattgt caggttgaaa
    12241 atggacgtgt tcgttttcaa ggagacgtga gagctattat cgaaaccaac ctttggcttc
    12301 gggcagcaga tcgtatcaaa attatcgtag gaacgttccc agctaagact tttgaagagc
    12361 tatttcaggg agttttcgct ttagattggg aaaattattt accacttgga gctcggttcc
    12421 cgatttcaaa agctaaatgt gttaagtcca aacttcacaa tgagcccagt gttcaggcta
    12481 tttctaagaa agctgttgtc aagaaattgc agaaacacta tgctcgccca gaaggggttc
    12541 ctttgatgga gaatggtcca gagtttaaga ttgaggtctc tattctcaaa gatgtggcaa
    12601 ctgtcatgat tgatacgacc gggtctagcc tctttaaacg tggttatcgt accgaaaaag
    12661 gtggcgctcc tatcaaggaa aatatggcag cagccatttt acaactttct aactggtatc
    12721 cagacaagcc tttgattgat ccgacctgtg gttcggggac tttctgtatt gaggcagtta
    12781 tgattgctag aaagatggcg ccaggtcttc gtcgctcttt tgcatttgag gaatggaact
    12841 ggatcagcga tcgcttgatt caagaagtgc gcacagaagc ggctaaaaaa gtagaacgta
    12901 agcttgagtt ggatatcatg ggctgtgata ttgatgctcg catggtggaa attgctaagg
    12961 ccaatgctca ggcagctggt gttgcaggag acattacttt taagcagatg cgcgtgcaga
    13021 atttacgttc cgataaaatc aatggagtaa tcatttccaa tccgccttat ggtgaacgtt
    13081 tgtcagatga tgcaggggtg accaagctct atactgagat ggggcaagta tttgcaccgc
    13141 tgaaaacttg gagcaaattt atcctgacta gtgatgaagc ttttgaaagc aagtatggta
    13201 gccaagcaga taagaagcgt aagttataca acggaacctt gaaagtggat ctatatcaat
    13261 attttggtca gcgtgtcaaa cggcaagagg taaaatagaa agggatactc atgagtaaaa
    13321 aaagacgaaa tcgtcataaa aaagaaggtc aagaaccgca atttgatttt gatgaagcaa
    13381 aagagctaac agttggtcaa gctattcgta aaaatgaaga agtggaagca ggagtcttgc
    13441 ctgaggattc cattttggac aagtatgtta agcaacacag agatgaaatt gaggcggata
    13501 agtttgcgac tcgtcaatac aaaaaagagg agttcgttga aactcagagt ctggatgatt
    13561 taattcaaga gatgcgtgag gctgtagaga agtcagaagc ttcttcggag gaagttccat
    13621 cttctgaaga catcttacta cccttgcctc tggacgatga ggagcaaggc ttggatcctc
    13681 tattgctaga tgatgaaaat ccaacagaaa tgactgaaga agtggaagag gagcaaaacc
    13741 tttctcgtct ggatcaagag gactcagaaa agaaaagcaa aaaaggcttt attttgaccg
    13801 ttttggcgct tgtatcagta attatttgtg tcagtgctta ttatgtctac cgtcaagtgg
    13861 ctcgttcgac taaggaaatt gaaacttctc aatcaactac agtcaatcaa tcggatgtgg
    13921 atgattttaa tacactttat gacgcctttt acacagatag caataaaacg gctttgaaaa
    13981 atagccagtt tgataaactg agtcaactca agactttact tgataagctg gaaggtagtc
    14041 gtgaacatac gcttgccaaa tctaaatatg atagtctagt aacgcaaatc aaggccattc
    14101 aagatgtcaa tgcacaattt gaaaaaccag ctattgtgga tggtgtgttg gataccaatg
    14161 ccaaagccaa atcggatgct aaatttacag atattaaaac tgggaatacg gagcttgata
    14221 aagtgctaga taaggctatc agtcttggta agagccagca aacaagtact tctagctcaa
    14281 gttcaagtca aactagcagc tcaagctcta gtcaagcaag ctcaaatacg actagtgagc
    14341 caaaaccaag tagttcaaat gagactagaa gtagtcgcag tgaagtcaat atgggtctct
    14401 cgagtgcagg ggttgctgtt caaagaagtg ccagtcgtgt tgcctataat cagtctgcta
    14461 ttgatgatag taataactct gcctgggatt ttgcggatgg tgttttggaa caaattctag
    14521 caacttcacg ttcacgtggc tatatcactg gagaccaata tatccttgaa cgtgtcaata
    14581 tcgttaacgg caatggttat tacaacctct ataagccaga tggaacctat ctctttaccc
    14641 ttaactgtaa gacaggctac tttgtcggaa atggcgctgg tcatgcggat gacttggact
    14701 actaagcagt cgttacaaaa ttctttcttt tcaaaagtaa aaatgataaa ataaaacaaa
    14761 tgaaacaaga ggagtgtcaa atgacaaaag ctaactttgg tgtcgtaggt atggccgtaa
    14821 tgggtcgtaa ccttgccctt aatattgaat cacgtggtta cacagttgct atctacaacc
    14881 gtagtaaaga aaaaacggaa gatgtgattg cttgccatcc tgaaaagaat tttgtaccaa
    14941 gctatgacgt tgaaagtttt gtaaactcaa tcgaaaaacc tcgtcgtatc atgctgatgg
    15001 ttcaagctgg acctggtaca gatgctacta tccaagccct tcttccacac cttgacaaag
    15061 gtgatatctt gattgacggt ggaaatactt tctacaaaga taccatccgt cgtaatgaag
    15121 aattggcaaa ctcaggtatc aactttatcg gtactggagt ttctggtggt gaaaaaggtg
    15181 ctcttgaagg tccttctatc atgcctggtg gacaaaaaga ggcctacgaa ttggttgcgg
    15241 atgttcttga agaaatctca gctaaagcac cagaagatgg caaaccatgt gtgacttata
    15301 tcggtcctga tggagctggt cactatgtga aaatggttca caacggtatc gagtacggtg
    15361 atatgcaatt gatcgcagaa agttatgact tgatgcaaca cttgctaggt ctttctgcag
    15421 aggatatggc tgaaatcttt actgagtgga acaagggtga attggatagc tacttgatcg
    15481 aaatcacagc tgatatcttg agccgtaaag acgatgaagg ccaagatgga ccaatcgtag
    15541 actacatcct tgatgctgca ggtaacaagg gaactggtaa atggactagc caatcatctc
    15601 ttgaccttgg tgtaccattg tcactgatta ctgagtcagt gtttgcacgc tacatttcaa
    15661 cttacaaaga agaacgtgta tatgctagca aggtgcttcc aaaaccagct gccttcaact
    15721 ttgaaggaga caaggctgaa ttgattgaaa agatccgtca agccctttac ttctcaaaaa
    15781 tcatttcata cgcacaagga tttgctcaat tgcgtgtagc ctctaaagaa aacaactgga
    15841 acttgccatt tgcagatatc gcatctatct ggcgtgatgg ctgtatcatc cgttctcgtt
    15901 ttttgcaaaa gattacagat gcttacaacc gcgatgcaga tcttgccaac cttcttttgg
    15961 acgagtactt cttggatgtt actgctaagt atcaacaagc agtgcgtgat atcgtagctc
    16021 ttgcggttca agctggtgtg ccagtgccaa ctttctcagc agctattact tactttgata
    16081 gctaccgttc agctgacctt ccggctaact tgatccaagc acaacgtgac tactttggtg
    16141 ctcacactta ccaacgtaaa gacaaagaag gaaccttcca ctactcttgg tatgacgaaa
    16201 aataagtagg tcagccatgg ggaaacggat tttattactt gagaaagaac gaaatctagc
    16261 tcatttttta agtttggaac tccagaaaga gcagtatcgg gttgatctgg tagaggaggg
    16321 gcaaaaagcc ctttccatgg ctcttcagac agactatgat ttgattttat tgaacgttaa
    16381 tctgggagat atgatggctc aggattttgc agaaaaattg agtcgaacta aacctgcctc
    16441 agtcatcatg attttagatc attgggaaga cttgcaagaa gagctggaag ttgttcagcg
    16501 ttttgcagtt tcatacatct ataagccagt ctttatcgaa aatctggtag cgcgtatttc
    16561 ggcgatcttc cgaggtcggg acttcattga tcaacactgc agtctgatga aagttccaag
    16621 gacctaccgc aatcttagga tagatgttga acatcacacg gtttatcgtg gtgaagagat
    16681 gattgctctg acccgccgtg agtatgacct tttggcgaca cttatgggaa gcaagaaagt
    16741 attgactcgt gagcaattgt tggaaagtgt ttggaagtat gaaagtgcga ccgagacaaa
    16801 tatcgtagat gtctatatcc gctatctacg gagcaagctt gatgttaaag gtcaaaaaag
    16861 ctacattaaa accgtgcgtg gtgttggtta caccatgcaa gaatagaaaa gcagttgcag
    16921 ttgtgtaact gcttttttga ggagttttta tatattgaca tgcagtcggg tctttgctac
    16981 aatcagttat ggaggatata taaatgaaac ttttgaaaaa aatgatgcaa gttctactag
    17041 cagtcttttt ctttggtttg ctagctacaa atacggtatt tgcaaatacc acaggtggcc
    17101 gatttgttga taaggataat agaaaatatt atgtaaaaga tgatcataaa gcaatctatt
    17161 ggcataaaat agacggtaaa acttactatt ttggtgatat tggagagatg gttgtcggtt
    17221 ggcaatactt agaaattcat ggaacaggtt atcgtgataa tttattcgat aaccaaccag
    17281 ttaatgaaat tggccttcag gagaagtggt actattttgg acaagatggt gctttgctag
    17341 aacaaacaga taaacaagta ctagaggcaa aaacgtctga aaatacagga aaagtatacg
    17401 gtgaacaata tcctctatct gctgaaaaga gaacttatta ttttgataat aattatgctg
    17461 taaagacagg ctggatttat gaagacggca attggtatta tttaaataag ctaggaaatt
    17521 ttggcgatga ttcttacaat ctactaccaa ttggtgaagt tgctaagggt tggactcaag
    17581 attttcatgt tactattgac attgatagaa gcaaacctgc tccatggtac tacctagacc
    17641 cagaaactgg cattatgcga acaggatggc aatatctagg taataactgg tactacctcc
    17701 gttcatcagg agcaatggcc actggctggt atcaggaagg taccacttgg tattatttag
    17761 accagccaaa tggcgatatg aaaacaggtt ggcaaaacct tgggaacaaa tggtactatc
    17821 tccgttcatc aggagctatg gcaactggtt ggtatcaaga tggttcaact tggtactacc
    17881 taaatgcagg taatggagac atgaagacag gttggttcca ggtcaatggc aactggtact
    17941 atgcttatag ctcaggtgct ttggcagtga atacgaccgt agatggctat tctgtcaact
    18001 ataatggcga atgggttcgg taatgacagg gcgcttataa ttatattaga acactcgctt
    18061 aatcaaagaa gtgactttgt tgtacttgac ctgacgattg gggagattaa aagcatgtga
    18121 aatctacaca tgctttttcg ttagttatga gtgttgaact tgactaacca ttgacaaaag
    18181 ataagagcaa ttaaaataag atacaaaaat atcaatgcta actgcaccga aacgcccgat
    18241 gctatggata gggctaatag ggagagcagg gacggggcga gaatgtccac tgtgctcaga
    18301 gcagagccca ccgtccccat cttgtcactg gggatatagg caaagacagc tgcttgtagg
    18361 cgagggctga gaatgccgat aatcgtagaa ctgatgaaac tggtcatgaa aattacgata
    18421 taggcttgac aaaggatact agttattaga gccaataggg aaatctcaca gaaaaccaag
    18481 aggtgcgtga aacggatatt tttaaataga ttactgctgg tcatattgcc aaggatagct
    18541 ccacaagaca tgatgatgga gagcagggcg aggagttgcc caatgctcag ttgtgctagt
    18601 gtctgttgga tgaagcggag ggcaatcagc cgaggggaca catccaagat ggcaatcata
    18661 ctggtcgtca gaaacagtag tatgacggta tcttttaact tcagtagcac agccagcgac
    18721 tgtttaagat gttgaaaata tttcttaaaa ctcagtgctg tatgtgacat ttcaatcctt
    18781 ttttcaacct catacaaggt atgtcgaata acatacaggc ccaaaaaggc aatgacaaaa
    18841 gtcagagtgt tgataaggga aatagtttga atacttataa cattgataag gaatgcgcca
    18901 gccagattgg cgacaatgcg gacaaccctc atcagagact gcctgaaccc catggcatca
    18961 tgcaggtcgt ccttaattac actgatgtag agggcgttca tcatgtaggc agacaggtag
    19021 ctcaaggtgt cagagatgag gttgatgatg acaatcataa tgactgaaac taatgaaaag
    19081 ggcgacaaga cgagaaatac tgtcaaaata gcgtagagca ggattttgat tttggcaata
    19141 cagagtgcgt gtttgactct attttcttga aaatctccta gaatcccgag aaagagttgc
    19201 gatagtaggg gaaccatctc tgaaatggaa atcagtaaaa tcgctagcgg agcgaaattg
    19261 tactgagcca cataattgat aatggcgagg tagaaaatac tgtcgccgaa tgatgaaaaa
    19321 cagctgttta gcagcaactg tctatatatg ttgtttgtcc aaaataattt catacatttc
    19381 tccttatgtc tgcacatcga atgggaattt attatttaat agacaccaat atacccccat
    19441 gcttcctatt ccgaagtcaa acaaatctgc tttaccacta tctccttgaa acatcagtaa
    19501 accgtgatca tctcgttcag aacatgctaa aattacctgt tggatttttt catcagtaat
    19561 ttgttttgat tgtagacagt ggtttgtagt aagctagtta ttccgtggca atatcctgtc
    19621 atcattttta gatgatggtt aaaaacaaat tcttgatatt tactaataat atctttgttt
    19681 ccgtcacaat cgtacataca aagatataag attattccgg aaattccttt gcaccaagaa
    19741 agttgtgaat ttcctaaatt ttcagtatta gaagtaactt tttctaataa tttttttaat
    19801 tcagtatgga atgtatggag atcattatag aacatagaag gttctaagac tttagaatag
    19861 gcaaataaag cctatgcaat tccacaatat ccatgagcaa agctatagtc taaaatgctt
    19921 tctttggcta tatctctttg taggaaataa tgctaaattt cccctatact attgtggatg
    19981 aaaattttaa gagtattgtc attggtaaat tgatagtatt ttattaatga taataggaca
    20041 ccagattttc ccaatgcaaa gtctatttcc tctagagtat cataattctc tattaatttc
    20101 ttagcggaga cgtttgctaa ttgtagatag tattgatttt tactgataga aaataaatgt
    20161 aggagtaacc atagatagcc tgcatcacca aatagcagtg agtattgata tttatatgtg
    20221 tgtgtcgttc taattgtcac tgccttcttg atgatagaga gtattttaga atccagttct
    20281 ggggggtaca atttatttag aggaaacagt agtccagcta ttccgtgttg gaatgataaa
    20341 ttacttacga aatttccaaa ttctgttgaa gaagtgatcc ttccttcaga atttacagtt
    20401 ttatctagta aaaatcgtag aacactatta cattctgttt tgtaatcata tttatgttcc
    20461 tctatttttt taattttgac taaattattt gtttgactta aatttagtag acattgtaac
    20521 caaaatagtt gctcatctgt gagctgacct tgagtatgtg atagttctag taattgaata
    20581 ggatccttta gttagattca atcaatctat aacacaacaa cataataata cttttaggat
    20641 aacttgtcaa atattatagt aaaatgaaat aa
//
LOCUS       DAVLHB010000038        20261 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLHB010000038 DAVLHB010000000
VERSION     DAVLHB010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.038"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            2..74
                     /locus_tag="VXE36_001510"
     tRNA            2..74
                     /locus_tag="VXE36_001510"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VXE36_001511"
     tRNA            99..171
                     /locus_tag="VXE36_001511"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VXE36_001512"
     tRNA            177..258
                     /locus_tag="VXE36_001512"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VXE36_001513"
     tRNA            277..349
                     /locus_tag="VXE36_001513"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VXE36_001514"
     tRNA            372..443
                     /locus_tag="VXE36_001514"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VXE36_001515"
     tRNA            451..536
                     /locus_tag="VXE36_001515"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VXE36_001516"
     tRNA            546..619
                     /locus_tag="VXE36_001516"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VXE36_001517"
     tRNA            635..708
                     /locus_tag="VXE36_001517"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VXE36_001518"
     tRNA            714..787
                     /locus_tag="VXE36_001518"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VXE36_001519"
     tRNA            801..874
                     /locus_tag="VXE36_001519"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VXE36_001520"
     tRNA            885..974
                     /locus_tag="VXE36_001520"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            985..1058
                     /locus_tag="VXE36_001521"
     tRNA            985..1058
                     /locus_tag="VXE36_001521"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1019..1021,aa:Met,seq:cat)
     gene            1062..1134
                     /locus_tag="VXE36_001522"
     tRNA            1062..1134
                     /locus_tag="VXE36_001522"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1095..1097,aa:Phe,seq:gaa)
     gene            1154..1224
                     /locus_tag="VXE36_001523"
     tRNA            1154..1224
                     /locus_tag="VXE36_001523"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Gly,seq:tcc)
     gene            1260..1333
                     /locus_tag="VXE36_001524"
     tRNA            1260..1333
                     /locus_tag="VXE36_001524"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1294..1296,aa:Ile,seq:gat)
     gene            1340..1427
                     /locus_tag="VXE36_001525"
     tRNA            1340..1427
                     /locus_tag="VXE36_001525"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1374..1376,aa:Ser,seq:gct)
     gene            complement(1553..2488)
                     /locus_tag="VXE36_001526"
     CDS             complement(1553..2488)
                     /locus_tag="VXE36_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0779798.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2485..3345)
                     /locus_tag="VXE36_001527"
     CDS             complement(2485..3345)
                     /locus_tag="VXE36_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0779799.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISNQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3453..5615
                     /locus_tag="VXE36_001528"
     CDS             3453..5615
                     /locus_tag="VXE36_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0779800.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRTTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYKNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     ELQENGEVYSGAELMYAGLTVILSQGDFLSKQYIFRRL"
     gene            5650..6909
                     /locus_tag="VXE36_001529"
     CDS             5650..6909
                     /locus_tag="VXE36_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0779801.1"
                     /translation="MKWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6923..7789
                     /locus_tag="VXE36_001530"
     CDS             6923..7789
                     /locus_tag="VXE36_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0779802.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7803..8636
                     /locus_tag="VXE36_001531"
     CDS             7803..8636
                     /locus_tag="VXE36_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0779803.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            8637..8717
                     /locus_tag="VXE36_001532"
                     /pseudo
     CDS             8637..8717
                     /locus_tag="VXE36_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8994..10436
                     /gene="gtfA"
                     /locus_tag="VXE36_001533"
     CDS             8994..10436
                     /gene="gtfA"
                     /locus_tag="VXE36_001533"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0779804.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            10574..11767
                     /locus_tag="VXE36_001534"
     CDS             10574..11767
                     /locus_tag="VXE36_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0779805.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12454..14433
                     /locus_tag="VXE36_001535"
     CDS             12454..14433
                     /locus_tag="VXE36_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779806.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            14500..15996
                     /locus_tag="VXE36_001536"
     CDS             14500..15996
                     /locus_tag="VXE36_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779807.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15996..16922
                     /locus_tag="VXE36_001537"
     CDS             15996..16922
                     /locus_tag="VXE36_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779808.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16931..17998
                     /locus_tag="VXE36_001538"
     CDS             16931..17998
                     /locus_tag="VXE36_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779809.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18009..18935
                     /locus_tag="VXE36_001539"
     CDS             18009..18935
                     /locus_tag="VXE36_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779810.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(19010..20261)
                     /locus_tag="VXE36_001540"
                     /pseudo
     CDS             complement(19010..20261)
                     /locus_tag="VXE36_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5855 a         3660 c         4369 g         6377 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttaacgcggg atggagcagc tcggtagctc gtcgggctca
     1021 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
     1081 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccattttat
     1141 tgatagtatt tatgcgggtg tagtttagtg gtaaaactac agccttccaa gctgttgtcg
     1201 cgagttcgat tctcgtcacc cgctttgaac tttgttcaaa ttaccaagtt ttttaacttg
     1261 ggcgcgtagc tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt
     1321 ccactcgtgc ccattaattg gagaattact caagaggctg aagaggacgg tttgctaaat
     1381 cgttaggtcg ggtaactggc gcaagggttc gaatccctta ttctccgttt taatgagagt
     1441 ttgtaactct cttttttgtt tttagagaca ataaaacttc agatccgtaa aacttaattg
     1501 aattactaat ctgaagttat ttttatatcg tttatattat aattgtgtta ttttacttcc
     1561 aactattgag agaaatttcg ccactattta gccagatttc ttttccgtta tcacattgaa
     1621 ttaaaagttt tccattttct gagatgtctt tagcaagtcc cttgtagtct ttttgctcta
     1681 gtgtgaaagt gacttctttt cctagaatga atgactgttt tttgtatagg tataatagct
     1741 cttctgctgg tgtttcgaag aaagcacgcc agatttctat gattaattca ttccttgtta
     1801 taggagctgt agctttaaat aagctggcag ctttttcttt taattcctga gggaagtctt
     1861 taatagtgaa attgatacct actccaataa tgatatctgt gactaagcca gtttctacag
     1921 aggtcattgc ttcagtaagg attcctccaa ttttatgatt gtttagatag atatcattga
     1981 cccattttat gtcgacatct attaaagtta ggttcttaat ggctttgtag acagctccag
     2041 ctacaagtag tgtgtaggat ggtaatttgt cataggggag atttggttta agatggagtg
     2101 tcatataaat tccaccttgt ggtgagtaga aggaacgttg aaaacggcct cggcctgctg
     2161 tttgatagga agctagatag agggtatttg cttcatggcc taaatcaatt gcttcttttg
     2221 catctagttg tgttgatttt gtttcgggtt taaagctgac tttaattgga agattttctt
     2281 ctagaatctc tggaagaata aggtcaccat tcatcagttt gtatcctcta tttttgatac
     2341 tatcaatttc aatgccttct tgttctagtc gcttgatggc tttccaaatt gatgttcggc
     2401 ttagggatag tttttctgcg attttttctc cgctgatata gtcggtttct ttagatagga
     2461 tttggtagac agcttggtag gatttcataa tgttgccttt ctcactagtt ggtattgaga
     2521 gtattctttt cttgtatgac ttggagtctg attaaagtat tgtttataag ctttcgaaaa
     2581 atggagtgga tctgaaaaac ctaccgagta tgcaattacc ttgatggact cttgggtatt
     2641 ttcgagaagt tgtctagctc ggtgcattcg aacgtagagt aggtattctt tgggtgataa
     2701 ggtattaaat tctttgaata cgcttgataa gtagcttctg tgaacggata gttcttttgc
     2761 taaatcttga attgtaagtg attgaggata gtggctatca attaatcgtt tgcattcaag
     2821 atagagttgg tgggttgatg aaatattctt ttttttctga ttgggagcaa tagttcccag
     2881 atgaaacatc agttcatgaa gttgtcccat gatatggagt tgagctaatt cacttgattt
     2941 tgtaatctga gcgaagcgga caatgtctga gatgagtttt gcagtagtct gggtatgaca
     3001 agtttcagat tggatgagat aggattgatt agaaatttga gaaagagcaa aataatcagg
     3061 ggatttccct ccagtgattc ctaaccagta gtaggcccaa ggttctttac tatctgcttg
     3121 ataaaaggtt agttcctctg gttttaatag aaagaaatct ccttctttta aatcaacaat
     3181 tttacccttg taataaaatt ttccttgtcc tttagtaatg taatgtagaa cgtatgtatc
     3241 acgaatggct ggaccaaaag agtaattagg tgtgcattcc tcatatccat aaaagcttag
     3301 ggcaaggtcg attgttccag tctggtattc tgaaaaaact aacatgtgct acctcctacc
     3361 taacatttta ccatattctt gagacatttt tctattttgg aaagcgattt caggtgataa
     3421 aatataatca ataaagtgat gaggtgaagt aaatgggagt taggatagag aataatctat
     3481 tttatgttga gagtaaaaat ctaagtttga ttattgaaaa tcgaaatggc tacttacttt
     3541 tgaaacattt aggaaagact attaagaact ataaaggttc caatagtgtt tatgaacgag
     3601 accatgcctt ttcaggaaat ccaacggcta ctaatcgaac ctttagttta gatactcagc
     3661 gacagatttt tggacaacat ggcttaggag attttaggaa accaaccata caggttcagc
     3721 atagtgtaac tgaagtaaca gactttcgat ttgtagaagc aaagatttta aaaggtcaga
     3781 atggtccaca gggcttacct tctccacata gcatggacga tacagagact cttgtcttaa
     3841 tgttagaaga ttctaaggct caacttagtc tgactttgta ttatactact tttaataatg
     3901 atgcgactat tgctagctac agtaaattag ataataatag taatcaggaa gttgtcatcc
     3961 ataaagattt ttcttttatg gctgattttc cagctgcaga ttacgaaata gtaactctgc
     4021 agggtgctta tgctcgtgaa aagactgtta gacgtcaaca ggtagaacaa ggaatctttt
     4081 cgattagctc aaaccgaggt gcttctggtc atgctcaaac accagctctt ctactatgcg
     4141 aacaaggagt cacagaggat gctgggaatg tgtttgctat tcaactaatg tatagtggca
     4201 actttgaagc ttttgttcaa aaaaatcaat tgaatgaagt tcgggtggct attggcatta
     4261 atccagaaaa cttttcttgg aagttagctc ctgaggaata ctttgaaaca ccggtagctt
     4321 tagtgaccca ttcagatcag ggattaactg gtattagtca tgaaagtcag aattttgtac
     4381 tgaagcacat tatgctaagt gaattttcta aaaaagaacg tccaattcta atcaataact
     4441 gggaagctac ttactttgac tttcagagag aaaaactgtt agagttagca gatgaagcta
     4501 agaaagttgg cattgaactt tttgtattag atgatggttg gtttggcaat cgttttgatg
     4561 ataatcgtgc tttaggtgat tgggttgtta atgaggaaaa actgggtgga agtctagaaa
     4621 gtctgatttc agctatccat gaaagaggtt tgcagtttgg actttggtta gaacccgaaa
     4681 tgatttctgt agatagtgat ttgtatcgtc aacatcctga ctgggctatt caggttcctg
     4741 gctatgagca tacttattct cggaatcaat tagtacttaa tcttgccaat cctcaggtag
     4801 tagaatactt gaaaagtgtc ttagatcaac tcctatctta tcatgatatt gattacatta
     4861 aatgggatat gaaccgcaat atcactaagc tagggaatgg attaacttat ctagagacac
     4921 agatgcaatc tcatcagtac atgctggggc tttacgaact cgtttcttat ctgacagaga
     4981 agcacagcca tattctcttt gagtcctgct ctggtggtgg tggacgaaat gatcttggta
     5041 tgatgcgcta tttcccacaa gtctgggcta gtgataatac agatgctatt gcacgtttac
     5101 caattcaata cggttcatcc tatctctatc caaccatttc tatgggggct catgtgtcag
     5161 cagtaccgaa tcatcagatg gggcgaacga caccattaga aacacgtggc cttgtagcaa
     5221 tgatgggaaa tttgggctat gaacttgatt tgacaaattt atcagatgaa gagaaagcta
     5281 cgattgctaa tcaggtgaac ttgtataaag aattacgacc agtagttcag ttaggacaac
     5341 agtatagact aattaatcct gatactgcat ccaatgaagc tgctgtacaa tttaattaca
     5401 aaaatcaaac gattgtaacc tacgttcgcg ttttatctgt tgtagagacc atggaaacaa
     5461 ctttaaagtt aaaagatttg gatgaagagg gactatatga attacaggaa aatggcgaag
     5521 tttactcagg tgcagaactc atgtatgcgg gtttaactgt tattttatcc caaggagatt
     5581 ttttgagtaa acagtatatt tttagaagac tataattaag gtgtataaat ttataaagga
     5641 ggctttccaa tgaaatggta taaaaaaatc ggacttcttg caactacagg tttagctttg
     5701 gttgggctcg gcgcttgctc caactatggt aaatctgcgg atggcacagt gaccatcgag
     5761 tatttcaacc agaaaaaaga aatgaccaaa accttggaag aaatcactcg tgattttgag
     5821 aaggaaaacc ctaagatcaa ggtcaaagtc gtcaatgtac caaatgctgg tgaagtattg
     5881 aagacacgcg ttctcgcagg agatgtgcct gatgtggtca atatttaccc acagtccatc
     5941 gaactgcaag aatgggcaaa agcaggtgtc tttgaagatt tgagcaacaa agactacctg
     6001 aaacgcgtga aaaatggcta cgctgaaaaa tatgctgtaa acgaaaaagt ttacaacgtt
     6061 ccttttacag ctaatgctta tggaatttac tacaacaaag ataaattcga agaactgggc
     6121 ttgaaggttc ctgaaacctg ggatgaattt gaacagttag tcaaagatat cgttgctaaa
     6181 ggacaaacac catttggaat tgcaggtgca gatgcttgga cactcaatgg ttacaatcaa
     6241 ttagcctttg cgacagcaac aggtggagga aaagaagcaa atcaatacct tcgttattct
     6301 caaccaaatg ccattaaatt gtcggatccg attatgaaag atgatatcaa ggtcatggac
     6361 atccttcgca tcaatggctc taagcaaaag aactgggaag gtgctggcta taccgatgtt
     6421 atcggagcct tcgcacgtgg ggatgtcctc atgacaccaa atgggtcttg ggcgatcaca
     6481 gcgattaatg aacaaaaacc gaactttaag attgggacct tcatgattcc aggaaaagaa
     6541 aaaggacaaa gcttaaccgt tggtgcggga gacttggcat ggtctatctc agccaccacc
     6601 aaacatccaa aagaagccaa tgcctttgtg gaatatatga cccgtccaga agtcatgcaa
     6661 aaatactacg atgtggacgg atctccaaca gcgatcgaag gggtcaaaca agcaggagaa
     6721 gattcaccgc ttgctggtat gaccgaatat gcctttacgg atcgtcactt ggtctggttg
     6781 caacaatact ggaccagtga agcagacttc cataccttga ccatgaacta tgtcttgacc
     6841 ggtgataaac aaggcatggt caatgatttg aatgccttct ttaacccgat gaaagcggat
     6901 gtggattagg agtagagaga ctatgaaaaa agtattacaa aaatattggg catgggcttt
     6961 tgtggtcatc cccctcttgt tacaagcaat tttcttctat gtgccgatgt ttcaaggagc
     7021 cttttacagt tttaccaact ggacaggatt gacttataac tacaaatttg tcggcttaaa
     7081 caactttaag ctcctcttca tggatccaaa attcatgaat gcgattggct ttaccgcaat
     7141 cattacgatt gccatggtgg ttggtgagat tgcactcggg atcttcattg cgcgtgtctt
     7201 gaattctaaa atcaaaggcc aaaccttctt ccgtgcttgg ttcttcttcc cagctgtttt
     7261 atctggtttg acagtggctt tgatcttcaa gcaagtcttc aactacggtc ttccagcgat
     7321 tggaaatgcc cttcatattg aatttttcca aaccagtctt ttagggacta agtggggagc
     7381 aatctttgcg gctgtctttg tccttctttg gcaaggggtg gctatgccca tcatcatctt
     7441 cctagctggt ttgcaatcta ttccaactga gattacagag gcagcaagga ttgatggtgc
     7501 gactagcaag caagttttct ggaacattga attgccttac ttgctaccaa gtgtctctat
     7561 ggtctttatc ctagccctaa aaggtgggct gactgccttt gaccaagtct ttgccatgac
     7621 cggtggtggt ccaaacaatg ccacaacctc acttgggctc ttggtttata actatgcctt
     7681 taaaaacaac caattcggtt atgccaatgc cattgccgta atcttgttct tcttaattgt
     7741 agtgatttcg atcatccaat tgagagtatc taagaaattt gaaatttaag aggagaagca
     7801 tgatgaaaca agatgaaaga aaagccctga ttggcaaata cattctattg attctaggat
     7861 cggttctgat tttagtgccg ctccttgcta ccctctttag ttccttcaaa cccactaagg
     7921 atattgtaga taatttcttt ggctttccaa ccaacttcac atgggacaac tttagccgtc
     7981 tcttagctga tgggattgga ggctattatt ggaactctgt cgtcatcact gtcttgtctt
     8041 tacttgcagt aatgatcttt atccctatgg cagcctactc catcgctcgc aatatgagta
     8101 aaagaaaagc ctttaccatc atgtataccc tcttaatcct cggaatcttc gtacctttcc
     8161 aagtcatcat gattccgatt acggttatga tgagtaaact cggtttggct aatacctttg
     8221 gtttgatctt gctctacttg acctatgcga ttccacagac cctctttctc tatgttggct
     8281 atatcaaaat ctcgattcca gaaagtctgg atgaagcagc agagatcgat ggggctaatc
     8341 aatttacaac ctatttccgc atcatcttcc caatgatgaa accgatgcat gcgacaacca
     8401 tgatcatcaa tgccctttgg ttctggaatg acttcatgtt gccactcctt gtcttgaacc
     8461 gggattccaa aatgtggact ctgcctttgt tccaatacaa ctacgcaggc caatatttca
     8521 acgactacgg accaagcttt gcctcttacg tggtcggcat tatcagtatc accattgtct
     8581 atctcttctt ccaacgccat atcatttcag gaatgagcaa cggggcagtg aagtaatact
     8641 caatgaaaat caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg
     8701 aggttgtgga tgaaactgac gaagtcagta accataccta cggtaaggca acgctgacgt
     8761 ggtttgaaga gattttcgaa tagtataaga agagctcatg gaatctatag tctttgacac
     8821 agaggaagag ttcagcttgt tgataattct atgtagaaaa caagaaagta gtactttgtt
     8881 tatcacagtc tatattagta cgagtttgat gataaataga gatttaaaat gaattttatt
     8941 tatgaagcca gatcatatga gacttggctt caattagaaa aaggagagta atgatgccaa
     9001 ttcaaaataa aaccatgttg attacctatt ctgatagcct tggaaataat cttaaagact
     9061 tatatgataa tttggaagag cattttggag atgctattgg aggagttcac cttttaccat
     9121 ttttcccatc aacaggtgat cgtggatttg cgccagttga ctacgacgaa gtggactcag
     9181 cttttggtga ttgggaggat gttaagcgtt taggtgagag atattatctt atgtttgatt
     9241 ttatgattaa tcatatttct cgtcaatcca agtattataa ggactatcaa gaaaaacatg
     9301 aagccagtga atttaaagat ctctttttaa actgggataa gttttggcca gaaaaccgtc
     9361 cgacacagtc tgatgtagat ttaatttaca agcgtaagga tcgtgcacca aagcaagaga
     9421 ttgtgtttga agatggttca gtggaacatt tgtggaatac ctttggtgag gagcagattg
     9481 atcttgatgt gaccaaagaa gtaactatgg aatttatccg taagaccatt cagcacttgg
     9541 caagtaatgg gtgtgatttg attcgtctag atgcctttgc ttatgcagtg aagaaattgg
     9601 atactaatga tttctttgtg gaaccagata tttgggattt attggacaaa gttcgagata
     9661 tcgctgctga gtatgggaca gagcttttac ctgagattca tgaacactat tcgattcagt
     9721 ttaaaatagc agaccatgat tactatgttt atgattttgc tcttccaatg gtgacacttt
     9781 atactcttta cagttccaga acagagcgtt tggctaagtg gttaaagatg agcccgatga
     9841 agcaatttac gacgctagat acccatgatg ggattggagt agtagatgtc aaggatatcc
     9901 tgaccgatga ggagattgac tatgcttcaa atgaactcta taaggttgga gccaatgtca
     9961 aacgtaagta ctctagtgcc gagtataaca acttagatat ctaccaaatc aattcaacct
    10021 actattcagc gcttggagat gatgatgtca agtattttct cgctcgtcta attcaagctt
    10081 ttgccccagg tattcctcag gtttactatg tgggtctatt agcaggcaag aatgacttga
    10141 aattattaga agaaactaaa gaaggtcgaa atattaatcg tcattactat agcaacgagg
    10201 aaatagcaaa agaagtgcaa cgatctgttg tgaaggccct tctcaatcta ttttctttcc
    10261 gtaaccgttc agaagccttt gatctagaag ggactactga gatagagaca ccaacagctc
    10321 acagcattgt aatcaaacgt caaaataaag ataagtccgt aacagcagta gtagaaattg
    10381 atttgcaaaa tcagacttat cgggtaattg agaatggagt tgaagtatca ttttgaagcc
    10441 ttgatatggt ggataaaata gggtttttat tttggaaaac gtttcctttg ttttcaaatt
    10501 gctaaaaaag tggtacaata taggatagct tactattatc tgaatcagct gatttggaga
    10561 gaaaggattc attttgaaat caataggctt tattgaaaag ctgaaggggt tgtctagtaa
    10621 agagctgatt ttattgggaa ttatcctaag tatcttttta cccttttatc tttttgtagt
    10681 tgtactctgt ttatatatta tcagtttgat ttttacagga gacatgaaaa gtattcttca
    10741 gaaaatgggg gagcatccga tgctgcttct ttttcttagc tatagtactg ttatatccat
    10801 tcttgcacaa aattggatgg gtcttgtggc ttcagtagga atgtttctat ttactatttt
    10861 ctttttgcac tatcagtcga ttttatccca taaattcttt cgattgattt tgcagttcgt
    10921 cttgtttggt agtgtcttgt cagctgcttt tgccagttta gaacatttcc aaattgtgaa
    10981 gaaatttaac tatgcttttc tttcacccaa tatgcaggtg tggcatcaga accgggcaga
    11041 agtgaccttc tttaatccta attattatgg aattatttgt tgtttctgta ttatgattgc
    11101 tttctatctg tttacaacga ccaagttgaa ttggttgaaa gtattctgtg tgattgcagg
    11161 ctttgttaat ctctttggtt tgaactttac tcaaaatcga actgcctttc ctgctattat
    11221 cgctggagca attatctatc tctttacgac tattaaaaac tggaaggcct tttggcttag
    11281 tattggggtc ttcgcgattg gtttgagttt cctcttttct agtgatttgg gagttcgaat
    11341 gggtacttta gactcttcta tggaagaacg catttctatc tgggatgctg ggatggcctt
    11401 gtttaagcaa aatccttttt ggggtgaagg gccattgacc tatatgcact cttatcctcg
    11461 gatacatgct ccttatcatg aacatgccca cagtctttat attgatacga ttctgagtta
    11521 cggaattgtg ggtaccattt tattagtttt gtcttctgtt gctcctgttc gcttgatgat
    11581 ggatatgagt caggagtcgg ggaaacgtcc gattatcggc ctttatctat ctttccttac
    11641 agtggttgct gtgcacggaa tttttgactt ggctctcttc tggattcagt caggctttat
    11701 tttcttgcta gttatgtgca gtattccatt ggagcatcga atgttggtat cggacatgac
    11761 ggattaagtt ttataagttt gaaatcttct accttgggta ggagattttt ttatactatg
    11821 ggtatgtcgt gcatctgagg tgtaagtcct ctgtaggggt ccactaccgg tgaatacaat
    11881 agcgctcccc aagcctgact gtcgtgaggt agcggattaa aatggtctgg ggatagatcg
    11941 ttttaagtct gacgcaggaa ataagaattg tcagagaaag caatagtgaa atcgtaggct
    12001 atgaatagaa acgtgatagc gaggagcata tagtggataa ggtagcgaga aattttaaag
    12061 tataaaagat agtcttaatc tatatatgta aatcacaaaa gtaattgaat tcggaataag
    12121 gttggtgtga aaagacatag taaactgaat cttgaatact agaatgatac ttctacaata
    12181 ttgttataat ttaatttgaa ttccaaaatc acattgttcc gtccgtattt cattttactg
    12241 tatgtcttcc taaactccaa agtttctgcg tcaaatttcc tattttcact gtagtctttg
    12301 acacttcgaa cgacaatttg aatcatatat tcaaaaaaaa atgaaaaatt tgtgccaaca
    12361 agcctaaata ttctgaaaat ttgtttgatt tttaatggat aatgtgatat aatggttgtc
    12421 aatctataat tcacataaac agaggagtag aaaatgaaaa aaaatcgtgt atttgctaca
    12481 gcaggtcttg ttttattagc agcaggtgta cttgcagcat gcagttcttc aaaatcatct
    12541 gattcatcag cccctaaagc ttatggctat gtttatacag cagacccaga aaccttggac
    12601 tacctgattt caagtaaaaa tagtacaaca gtagtgactt caaatgggat tgatggttta
    12661 ttcactaacg ataattacgg taatcttgct cctgcagttg cagaggattg ggaagtctct
    12721 aaggatggtt tgacctacac ttataagatt cgtaaagggg ttaaatggtt tacctctgat
    12781 ggagaagaat atgcagaggt gacggctaaa gatttcgtga acggtttaaa acacgcagca
    12841 gataaaaaat cagaagctat gtatttagct gaaaattcgg ttaaaggctt ggcagattat
    12901 ctatcaggaa cttcaacaga tttttcaaca gttggtgtca aggcggttga tgattatacg
    12961 ttacaataca ctttgaacca gcctgaaccg ttctggaact ctaagttgac ctattctatt
    13021 ttctggcctc tgaatgaaga attcgaaaca tcaaaaggaa gcgattttgc taaaccaaca
    13081 gatccgacat ccttgcttta taatggtcca ttcttgttga aagggttgac tgcaaaatct
    13141 tctgtagagt ttgtaaaaaa tgagcaatat tgggataaag aaaatgtcca cctagatact
    13201 atcaatctag cttactatga tggatcagat caggagtcgc tagagcgtaa cttcactagt
    13261 ggagcttata gttatgcccg tctttaccct accagctcca actattctaa ggttgcagaa
    13321 gaatacaagg acaatatcta ttacacacaa tcaggctctg ggattgctgg tctgggtgtg
    13381 aatattgatc gccaaagtta caactatact tctaaaacta cagattcaga gaaagtagct
    13441 actaagaagg cattgcttaa caaagatttc cgtcaagcct tgaattttgc tcttgatcgc
    13501 tcagcttact cagctcaaat caatggtaaa gatggagcag ctttagcagt tcgtaattta
    13561 tttgtaaaac cagactttgt ttcagctggt gagaagacct ttggtgattt agtcgctgct
    13621 caacttcctg cttatggtga tgagtggaaa ggtgtgaatt tagctgatgg gcaggatggt
    13681 ttattcaatg ctgacaaggc caaggcagag tttgcgaaag ctaagaaagc tttagaagca
    13741 gacggcgttc agtttcctat tcatctggac gttccagtag accaagcatc aaaaaactac
    13801 atatctcgta ttcagtcttt taaacaatct gtagaaacag ttcttggtgt tgaaaatgtc
    13861 gttgttgata ttcaacaaat gacaagtgat gaattcctta atattactta ctatgctgcc
    13921 aatgcttcat ctgaggattg ggatgtatca ggaggagttt catggggtcc agactatcaa
    13981 gacccatcta cttacctgga tattttaaaa acaactagca gtgaaactac aaaaacatat
    14041 ttaggatttg ataatccaaa tagcccttca gtagttcaag ttggtttgaa agaatacgat
    14101 aaattagttg atgaagctgc cagagagaca agcgacttga atgtccgtta tgaaaaatat
    14161 gcagcggctc aagcatggtt gacagatagt tcactcttta ttcctgctat ggcttcttct
    14221 ggtgcagcac cagtgctttc acgaattgtt ccatttactg gagcttctgc gcaaacaggc
    14281 tctaaggggt cagatgttta cttcaaatat ttgaaattac aagataaagt ggtgactaag
    14341 gaagagtatg aaaaagctcg tgaaaaatgg ttgaaagaaa aagctgaatc aaatgagaaa
    14401 gctcaaaaag aattggcaag tcatgtgaag taaataattt ctaatagaac tttctctcca
    14461 tgaggagaag gttcttttgg gatttttaaa ggaaataata tgaaaaaata tatttttatg
    14521 cgtgttttgc ggtcattggt ttcgattttc ttagtaacga ctttgaccta cacgattatc
    14581 tataccttgg ttcctcgaaa attgattttc aagcaggatc ctaactataa taaaattgcg
    14641 acaacggctg ataaacgtga taactatgaa aatactgtgt ttgagcgtat gggctacatt
    14701 gagtattacg atactaaaga gttgcaagaa aaggcaagta gcatggattc ttctgtaaca
    14761 gtagaagcaa atgcgaccaa taaagctatt tatgaaaagt acatcaatca attaggtcat
    14821 ggttggactt tgggagaatt tactgaaagt ggtcaattct atgctactcg tgaaattcca
    14881 atttttgaac gtgtttttca cttctatgct aacttgattg acattgacca tacaaataaa
    14941 atccaagacc ctgaaaatcc agacttgaaa cgctaccttc gttttgaaaa tgatccagct
    15001 atcggatggt cattggtcgg ttcaggaact aaacataaat atctcttgta ctttaacagt
    15061 cagttcccat ttgttcatca aaactttgtg aacttgaatt taggtgactc ttacccaacc
    15121 tatgctaata caccagttct tcaggttatt actcaaggtc aaggacaaac caaaactgcc
    15181 caagttcagt tcccaacagg taagaaaacg tcttctgtaa atatttactc aagaacctac
    15241 aagtcaccta gtcaggctga ctctcgtgaa gtagctagct atgggaaaga tgatccttat
    15301 acagcgactg aaagtaatta ccaatatcca tctatgattg tcagctctgc tattactggt
    15361 ttgattggtt tggttcttgc ctatgctctt gccgtgccac ttggttcagc catggctcgt
    15421 ttcaagaaca cttggattga tagcctctca acagggactt tgaccttctt gcttgctctt
    15481 ccaacgattg ccttggttta catcgttcga ttgattggat catctattgc ccttccagat
    15541 tcattcccta tcttgggagc tggagattgg cgttcttacg ttttaccagc agtcatcctt
    15601 ggtttgttgg gtgctcctgt tacagccatt tggattcgtc gttacatgat tgacttgcaa
    15661 tctcaagact ttgttcgttt cgctcgtgca aaaggtttgt ctgaaaaaga aatttcaaac
    15721 aaacacatct ttaaaaatgc catggttccg ctggtttcag gaattcctgg tgccattatt
    15781 ggggttatcg gtggtgcaac ccttactgaa acagtcttcg ccttcccagg tatgggtaaa
    15841 atgttgattg actctgtaaa agcatctaat aactctatgg tcgttggtct tgtcttcatc
    15901 tttacatgta tttctatctt ctcacgtctt ttgggagata tttggatgac tattattgac
    15961 ccacgtatta aattgactga gaaaggaggc aaataatgtc tacaatcgat aaagaaaaat
    16021 ttcagtttgt aaaacgtgac gattttgcct ctgaaactat tgatgcgcca gcatattctt
    16081 actggaaatc agtgtttaaa caatttatga agaaaaaatc aactgtagtc atgttgggaa
    16141 tcttggtagc catcattttg ataagtttca tctacccaat gttttctaag tttgatttca
    16201 atgatgtcag caaggtaaac gactttagtg ttcgttatat caagccaaat gcggagcatt
    16261 ggttcggtac tgacagtaac ggtaaatcgc tctttgacgg tgtctggttc ggagctcgta
    16321 actccatcct catttctgtg attgcgacag tgattaactt ggttatcggt gtttttgtcg
    16381 gtggtatttg gggtatttca aaatcagttg accgtgtcat gatggaagtt tacaacgtca
    16441 tctcaaacat cccacctctt ttgattgtta ttgtcttgac ttactcaatc ggagctggat
    16501 tctggaatct gatttttgcc atgagcgtaa caacatggat tggtattgcc ttcatgatcc
    16561 gtgtgcaaat cttgcgctat cgtgacttgg aatacaactt ggcgtcacgt actttgggaa
    16621 caccaacctt gaagattgtt gccaaaaata tcatgcctca attggtatct gttattgtga
    16681 caaccatgac tcaaatgctt ccaagcttta tctcatacga agccttcttg tctttcttcg
    16741 gtcttggatt accgattaca gtgccaagtt tgggtcgttt gatttcggat tattcacaaa
    16801 acgtaacaac caatgcttac ttgttctgga ttccattgac aacccttgtc ttggtatcct
    16861 tgtccctttt cgtagttggt caaaacttag cggatgctag tgatccacgt acacatagat
    16921 aggagtagaa atgacaaaag aaaaaaatgt aattttgact gctcgcgata ttgtcgtgga
    16981 atttgacgtt cgtgacaaag tattgacagc cattcgcggc gtttcccttg aactagttga
    17041 aggagaagta ttagccttgg taggtgagtc aggatcaggt aaatctgttt tgacaaagac
    17101 cttcacaggt atgctcgaag aaaatggtcg tattgcccaa ggtagtattg actaccgtgg
    17161 tcaggacttg acagctttat cttctcacaa ggagtgggaa caaattcgtg gtgctaagat
    17221 tgcgactatc ttccaggacc caatgactag tttggacccc attaaaacaa ttggtagtca
    17281 gattacagaa gttattgtaa aacaccaagg aaaaacagct aaagaagcga aagaattggc
    17341 cattgactac atgaataagg ttggcattcc agacgcagat agacgtttta atgaataccc
    17401 attccaatat tctggaggaa tgcgtcaacg tatcgttatt gcgattgccc ttgcctgccg
    17461 acctgatgtc ttgatctgtg atgagccaac aactgccttg gatgtaacta ttcaagctca
    17521 gattattgat ttgctaaaat ctttacaaaa cgagtatcat ttcacaacaa tctttattac
    17581 ccacgacctt ggtgtggtgg caagtattgc ggataaggta gcggttatgt atgcaggaga
    17641 aatcgttgag tatggaacgg ttgaggaagt cttctatgac cctcgccatc catatacatg
    17701 gagtctcttg tctagcttgc ctcagcttgc tgatgataaa ggggatcttt actcaatccc
    17761 aggaacacct ccgtcacttt atactgacct gaaaggggat gcttttgcct tgcgttctga
    17821 ctacgcaatg cagattgact tcgaacaaaa agctcctcaa ttctcagtat cagagacaca
    17881 ttgggctaaa acttggcttc ttcatgagga tgctccaaaa gtagaaaaac cagctgtgat
    17941 tgcaaatctc catgataaga tccgtgaaaa aatgggattt gcccatctgg ctgactagga
    18001 ggaaggaaat gtctgaaaaa ttagtagaaa tcaaagattt agaaatttcc ttcggtgaag
    18061 gaagtaagaa gtttgtcgcg gttaaaaatg ctaacttctt tatcaacaag ggagaaactt
    18121 tctcgcttgt aggtgagtcc ggtagtggga aaacaactat tggtcgtgct atcatcggtc
    18181 taaatgatac aagtaatgga gatatcattt ttgatggtca aaagattaat ggtaagaaat
    18241 cgcgtgaaca agctgcggaa ttgattcgtc gaatccagat gattttccaa gaccctgccg
    18301 caagtttgaa tgaacgtgcg actgttgatt atattatttc tgaaggtctt tacaatcacc
    18361 gtttatttaa ggatgaagaa gaacgtaaag agaaagttca aaatattatc cgtgaagtag
    18421 gtcttcttgc tgagcacttg actcgttacc ctcatgaatt ctcaggcggt caacgtcaac
    18481 gtatcggtat tgcccgtgcc ttggtcatgc aaccagactt tgttattgca gatgagccaa
    18541 tttcagcctt ggacgtttct gtacgtgccc aagtcttgaa cttgctcaaa aaattccaaa
    18601 aagagctcgg cctgacctat ctcttcatcg cccatgactt gtcggttgtt cgctttattt
    18661 cagatcgtat cgcagttatt tacaagggtg ttattgtaga ggttgcagaa acagaagaat
    18721 tgtttaacaa tccaattcac ccatatactc aagccttgct ttcagcggta ccaatcccag
    18781 atccaatctt ggaacgtaag aaggtcttga aggtttacga cccaagtcaa cacgactatg
    18841 agactgataa gccgtctatg gtagaaatcc gtccaggtca ctatgtttgg gcgaaccaaa
    18901 ccgaattggc acgttatcaa aaaggactaa actagtaatg gttttataat ttccatgtca
    18961 atttttatgg aaattaggct ctttgtcaac tgtagtgggt tgaagtcagc taagctcgag
    19021 aaaggacaaa tttcgtcctt tcttttttga tgttcaaagc gataaaaatc cgttttttga
    19081 agttttcaaa gtttcgaaaa ccaaaagcat tgcgcttgat aagtttgatg agattattgg
    19141 tcgcttccag tttggcatta gaatagtgta gttgaagggc gttgataatc ttttctttat
    19201 ctttgaggaa ggttttaaag acagtctgaa aaataggatg aacctgctta agattgtcct
    19261 cgataagttc gaaaaatttc tctggttcct tattctggaa gtgaaaaagc aagagctgat
    19321 agagctgata gtggtgtttc aagtcttccg aataactcaa aagcttgttt aaaatctctt
    19381 tattggttaa gtgcatacga aaagtaggac gataaaattg cttatcactc agtttacggc
    19441 tatcctgttg tatgagcttc cagtagtgct tgatagcctt gtgttcatgg gattttcgat
    19501 gaaactgatt catgatttgg acacgcacac gactcatagc acggctaaga tgttgtacaa
    19561 tgtgaaagcg atcaagaacg attttagcat tcgggagtga aacagtctag gagactgttt
    19621 cagcctgagc ctagaaattt gaaagcgaag ctgtttagcc aagtcatagt aagggctaaa
    19681 catatccata gtaatgattt tgacgcgaca tcggacggct ctatcatatt taagaaagtg
    19741 atctcggatg acagcttgtg ttctaccttc aagaacagtg atgatatcga gcttttcaaa
    19801 atcttgcgca ataaagctca tctccatctc ccgattgaaa cagtcactcc ccggactgtt
    19861 tcaacgtccc aagacataat cttaggcaga tttctaaaat tacactcaaa gtggaagtca
    19921 ttgagctttc gaatgacagt tgaagttgag atggaaagct gatgggcaat atcagtcata
    19981 gaaatctttt caattaattt ttgagcaatc ttttggttga tgatacgagg gatttggtga
    20041 ttcttcttga cgatagaagt ttcagcaacc ataattttag aacaatgata gcacttgaaa
    20101 cgacgctttc taaggagaat tctagtaggc ataccagttg tttcaagata aggaatttta
    20161 gaaggttttt gaaagtaata tttcttcatt tgacttccgc actcaggaca agatggagct
    20221 tcatagtcca gtttggcgat gatttccttg tgtgtatcct t
//
LOCUS       DAVLHB010000039        20063 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLHB010000039 DAVLHB010000000
VERSION     DAVLHB010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20063
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.039"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            1..822
                     /locus_tag="VXE36_001541"
                     /pseudo
     CDS             1..822
                     /locus_tag="VXE36_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(939..1286)
                     /locus_tag="VXE36_001542"
     CDS             complement(939..1286)
                     /locus_tag="VXE36_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0779811.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1397..3172)
                     /gene="spxB"
                     /locus_tag="VXE36_001543"
     CDS             complement(1397..3172)
                     /gene="spxB"
                     /locus_tag="VXE36_001543"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0779812.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3379..5622)
                     /locus_tag="VXE36_001544"
     CDS             complement(3379..5622)
                     /locus_tag="VXE36_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0779813.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5632..6003)
                     /locus_tag="VXE36_001545"
     CDS             complement(5632..6003)
                     /locus_tag="VXE36_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0779814.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(6014..6409)
                     /locus_tag="VXE36_001546"
     CDS             complement(6014..6409)
                     /locus_tag="VXE36_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0779815.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6593..6691
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6775..7596
                     /gene="thiD"
                     /locus_tag="VXE36_001547"
     CDS             6775..7596
                     /gene="thiD"
                     /locus_tag="VXE36_001547"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0779816.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIHPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPESVVIKGGHLKGGHLKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTH
                     GTGCTFAAVITAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7806..8438)
                     /locus_tag="VXE36_001548"
     CDS             complement(7806..8438)
                     /locus_tag="VXE36_001548"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0779817.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMDTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8431..9234)
                     /locus_tag="VXE36_001549"
     CDS             complement(8431..9234)
                     /locus_tag="VXE36_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0779818.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9234..9758)
                     /gene="thiW"
                     /locus_tag="VXE36_001550"
     CDS             complement(9234..9758)
                     /gene="thiW"
                     /locus_tag="VXE36_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0779819.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9763..10455)
                     /gene="tenA"
                     /locus_tag="VXE36_001551"
     CDS             complement(9763..10455)
                     /gene="tenA"
                     /locus_tag="VXE36_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0779820.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKVFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10466..11116)
                     /locus_tag="VXE36_001552"
     CDS             complement(10466..11116)
                     /locus_tag="VXE36_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0779821.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(11118..12503)
                     /locus_tag="VXE36_001553"
     CDS             complement(11118..12503)
                     /locus_tag="VXE36_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779822.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRVEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12504..13064)
                     /locus_tag="VXE36_001554"
     CDS             complement(12504..13064)
                     /locus_tag="VXE36_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0779823.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13326..13414)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13623..14252)
                     /locus_tag="VXE36_001555"
     CDS             complement(13623..14252)
                     /locus_tag="VXE36_001555"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0779824.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALRGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIMKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14254..15036)
                     /gene="thiM"
                     /locus_tag="VXE36_001556"
     CDS             complement(14254..15036)
                     /gene="thiM"
                     /locus_tag="VXE36_001556"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0779825.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            15120..15212
                     /locus_tag="VXE36_001557"
                     /pseudo
     CDS             15120..15212
                     /locus_tag="VXE36_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(15362..16030)
                     /locus_tag="VXE36_001558"
     CDS             complement(15362..16030)
                     /locus_tag="VXE36_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0779826.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(16245..16333)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16587..17723)
                     /gene="lctO"
                     /locus_tag="VXE36_001559"
     CDS             complement(16587..17723)
                     /gene="lctO"
                     /locus_tag="VXE36_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0779827.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18348..19838)
                     /gene="lysS"
                     /locus_tag="VXE36_001560"
     CDS             complement(18348..19838)
                     /gene="lysS"
                     /locus_tag="VXE36_001560"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0779828.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19966..>20063)
                     /locus_tag="VXE36_001561"
     CDS             complement(19966..>20063)
                     /locus_tag="VXE36_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0779829.1"
                     /translation="YDLEPMAQQVIPKAAFGYIASGAEDTFTSFQ"
BASE COUNT         6025 a         4384 c         3716 g         5938 t
ORIGIN      
        1 cgtaaccatg catatatgac gattgaggaa aagaaagtct ttcttgcccg ccatttgaag
       61 gctacagagg caggagaatt tgttacaatt gatgccttat ttcaggctta taaaaaggag
      121 ttaggtcgtt cctacacacg tgatgccttc tatcaactgt tgaagcgcca tggttggcga
      181 aatattatgc cacgtccaga acatcctagg aaagcagacg ctcaaaccat tgtcgcgtct
      241 aaaaataaaa tctcaattca agaagaaaag aaagcgcttt aaaagcagta gacgttttcg
      301 taaggttcgc ttgatgtacc aagatgaggc tggtttcggt agaatcagta aactgggatc
      361 ttgttgggct ccaataggag taggtccaca tgtccatagt cactatatac gagaatttca
      421 ctattgttat ggagctgttg atgcccatac aggcgaatca tttttcttaa tagctggtgg
      481 atgtaatact gagtggatga acgccttttt agaagagctt tcacaagctt atccagatga
      541 ttatctttta ctcgttatgg acaatgctat atggcataaa tcaagtacct taaagattcc
      601 gactaatatt ggttttacct ttattcctcc atacacacca gagatgaacc cattgaacaa
      661 gtgtggaaag agattcgtaa acgtggattt aagaataagg cctttcgaac tttggaagat
      721 gtcatgaatc aacttcaaga tgtcatacaa ggactggaga aggaggtgat aaagtccatc
      781 gttaatcgga gatggactag aatgcttttt gaaagcatat gagtattata tgcaatttct
      841 ttatataaaa agaccggatt gctccgatct ttcaatagtt catattctca atttctattt
      901 taaaaatagc taaggttaac gtcaaatgac tacgcgacct atttcatacg ataaaaatca
      961 agcactagac cagcaggtcc ttgaactaat aaggactctg ttccccaatc ggttacagtt
     1021 ggtccgtgta aaacctttat accaagctcg ttcaaccgtt tgtagttctg gtctacatcc
     1081 tcaacctcga tatgaataat gattcctgac tgaaagtttt ccaaaggaac caaatgattt
     1141 tgtgacaaca taaggcagtg actaccaatc gtaaactgag caaaaccatc atcagcataa
     1201 tctgcctttt tatccaaaat atgctccaag tcagcacaga cttggggaac atttgaaacg
     1261 ataatatcta attgatttaa attcatttac tctcctccat aaaaagaccg gattgctccg
     1321 atcttttaaa gttctgctct atgaaaatca aagaataaag tctacaagtt tcatatttga
     1381 ttttcggcga gaggaattat ttaattgcgc gtgattgcaa tccttcttct tccaagaaga
     1441 gacggaatgg tacgagttct tctgcttcgt atttttcctt gaaggctttg atagcttctt
     1501 ctgagtgaag ttttggatcc aattcaagta cttctactgg aagtggacgg tgttgagtga
     1561 tgcgagcatc gatgacaaca gttttacctt ctttgttcaa tttaacagct tctgcaacaa
     1621 ctgcatcgat gtcttcgata cggtcaactg tgaatccaac agctccttga gcttccgcaa
     1681 ttttagcgta gtcagcgttt gtgaagtcta caccaaacaa gtgtttgttt gtatcttcgt
     1741 atttgttctt gatgaagccg tactcagcat ttgagaagac aaggttgata actggaaggt
     1801 cgtattgaac gtttgtgata acgtctgggt agcacatgtt gaatgctccg tcacccatga
     1861 tgttccatac ttggcgatct ggattgtctt tcttagcagc gataccacca ggaagggcaa
     1921 tacccattgt cgcaaagagt ggagatgtac gccacatgtt cttaggtgtc atgtgaaggt
     1981 gacgagtaga tgtttgagta gtgttaccta cgtcgattga gtagatagcg tcttgatcag
     2041 catgtttgtt gattgcattg taaacttgat acaattgcaa ttcaccctca gttttacctt
     2101 cgagtttgtt catgtaatca cgccagtttt ggttgttctt aacgtttgca cgccaccatg
     2161 gagttgattc aactgggttt actttgtcaa ggatagcttt agctgcttga ccagcatcac
     2221 caaggattga agcgtcaagg gcatgacgtt taccaagttt gtaagggtcg atatcaactt
     2281 ggatgaattt ttcagtgttc ttgaatgctt cgtaaacttc agcaaatggg aagtttgaac
     2341 caaggaaaag aactgtgtct gcttcaaaga ccacttcgtt ggctggtttc caaccaacac
     2401 gataagcaga acctgtcaaa ccttcatagt tccattcgaa agcttcaaag tttttaccag
     2461 ttgtgatgat tggtgctttg attttacgtg acaattcagt aatcacttca ccagctttaa
     2521 caccaccaaa tccagcatag ataactgggc gttcagcatt gttcaagatt tcaacagctt
     2581 tgtcgatttc aacttcgttc aaagcaggag cgatgaatga gcgttcgtat gaacctgaac
     2641 cgtagtatga gttttcgtcg atttcttgga aaccgaagtt tactggaatt tcaacaacag
     2701 ctggaccttt tttagaaatt gcagcacggc aggcttcgtc aattactttt ggcaattgct
     2761 cagcgtaagc tacacgtttg ttgtaaacag cgataccgtt gtacattggg ttttggttaa
     2821 gctcttggaa agcatccatg ttcaattcgt taactggacg tgatccaagg atcgctagga
     2881 atggagtgtt atccatagct gcatcgtaaa caccgttaat caagtgagtc gcacctggac
     2941 cacctgaacc aactgcaacc ccgattgagc cgccgaattt agcttgcata accgctgcaa
     3001 gagcacctgt ctcttcgtgg cgaacttgta agaagcggat atctttgtct tcagccaaag
     3061 cgtccatcaa tgagctgagt gttcctgatg ggataccgta gattgtatct acgccccatg
     3121 ttttcaatac gttaagcatt gctgcagatg cagtaatttt cccttgagtc ataatgataa
     3181 ctctccttca atttttttag atttggagaa tacgattaca tagaattgga aacgttctcc
     3241 aaatttttac tattccactg tatcatattt atgctgactt ttctaaaaat ctgctcaaaa
     3301 ctctctattc tctattctaa tacagttttt aaagttctgt catttctgtt ttataacaaa
     3361 gaaatctagt cattactttt agtctatttt actaaaattt aacagaaggg aactggtcag
     3421 aacagataca gaactaaagg ccatggctag acctgccaat tctgggttga gagccagtcc
     3481 aacacctgaa aagactcctg ctgcaatcgg aattccgaca acattgtaga taaaagccca
     3541 gaaaagattg agtagaattc gatgaaaggt tttcttactc atatcaaagg cacgaaccac
     3601 tcctaaaaga ttattggttg tcaacaccaa atctgctgac tcgatggcga tatctgttcc
     3661 agctcccata gcaatcccca catctgctac actaagggca ggagcgtcat tgataccgtc
     3721 cccaacaaag gctactttcc ctgactgttg cagtttatgg atttcatggg ctttttcttc
     3781 tggcaagacg cctgcaatga cctcttcaat tccgatttga tctgcaatag cacgcgccac
     3841 accagcattg tctcctgtca gcatgactgt tcggagacca cgttttttta gctgactgat
     3901 ggctagctta gcattttcct taggaatatc ttgcaaagca agcaagcctt tgatttcatt
     3961 gtcaacagct aaaaacacaa ctgtcttagc ttctttttct agttcttcta gtttatcttg
     4021 ataagtatta gaaatatcca tgccatccag cattttagca tttccaagta aaacttgttt
     4081 tccattgatt cgccctgaaa cacctttccc gtgcaaggcc tgaaaatttt caacagtttg
     4141 aaactcaagt ccagcttcac tcgctcgctt aacgatagcc tcagccagtg ggtgttgaga
     4201 agcatcttcc aaggaggctg ccaatccaaa cacttctact tcgtcaccga tgatatctgt
     4261 taccacaggt ttcccttccg tcaaagtccc ggtcttatca aagacaagag tttgaacttt
     4321 ctggatttcc tgtaagacag ttccattttt gaggagaacc cccatcttgg cactacgtcc
     4381 tgtccccacc ataagggctg tcggtgttgc aagtcccaag gcacaaggac aggcgataat
     4441 caaaaccgcc actccgtaga gaagagagga cacaaagcta gctccaagca cgaccacact
     4501 atccctgagc aagacgaacc aaacccaaaa ggtcatgatt cctaaaatga caactactgg
     4561 gacaaaaatc cctgaaatct tatccgtcaa gtcctgaatc ggcgcacgac ttgtctgagc
     4621 tttcttcaca aaatccacaa tctgagccaa aacagtctct gagccaactt tttctgctct
     4681 aaagacaagc gttccactat gattgatggt tgagccaatg acagtatctc caactgtctt
     4741 gtccacaggc agactctcac ctgtcaccat ggattcgtca atactagaga caccttctac
     4801 tacgacacca tcaacagcaa tcttttcacc gggacgcact cgaatcaggt cgcctacctt
     4861 gacttgttcc aaaggaactt ggacataact atcatcactc aagacttctg cggttttagc
     4921 ttgcaagtcc agtaatttct ccacagcttg ggacgtattt tttctcattt tttcctcaaa
     4981 aactgctccc aaaagaacga aaaagaggat aaatccagca ctttcgaagt aaacagggag
     5041 accagcaaag agagcaacta ggctatagaa ataagccact agagttccca gcgcaaccaa
     5101 ggtatccatg ttggcattgt gctttttaaa actggcccaa gcactctgga tatatggctt
     5161 acctgcaact aacataatag gcgttgttgc taaaaaggtt ccccaatgca tgacttgatg
     5221 actaatgcta cctgccaaca tcccaatcat gagaatcaca agaggcacag taaagatact
     5281 agtaatccaa aaacgttgca ggagagatag agattttcga gtcttctcaa cgactgtata
     5341 gcttcccttt tgcatcttca tgccacaaga aaattcatgt cgccctaatt cttgaggcgt
     5401 aaaacgaatg actttctcct catctacgcc gattggttcc aagatacctt cttcttcaaa
     5461 cagaatttcc ttataacagt ttgaaggagt agcacgatga aaggtaatct cagctggaat
     5521 tcccttttga agctggatat gggctggatg atagcctttt tcagctcgga tacggatttt
     5581 ttgaatgcca ttttctaagc ttgctttcac aatttctgtc atagtctcca cctactctac
     5641 aatcatcttg ccgtgcatca tgttcatacc acaagcaaag ccaaactctc cagcctgttc
     5701 aggcgtgatt tccactacat actcttcccc cattggcagg ttcgcatgta caccaaaatc
     5761 tggaaaaaca atttgatcca gacatggtga aggatccttg cggtcaaaga caatgcgtgc
     5821 tggcactgat ttctttagga caatcaactc aggagtatag cctcccatga cttccactcg
     5881 aatctcttgg tatccgtttt tttgctgggc tttttgtcca gatttttcag gctttttgaa
     5941 aaaccaaaac aagataaatg cgataagggc aatacaaata atggttacaa tactatttaa
     6001 catgacgtct cctttacata caattacatc ttacttctgt tacagcactt gatttcttct
     6061 ctgaaatcac agcttccaag tcttccaagt cagtctgagt aaattcacat tctacaatca
     6121 agtcagccaa caaattccta atcctacggg aacaaacctt gtctttgata tcttggacaa
     6181 gtaaatcccg actttggtct agagttaaaa gggctgaata aacaaaggac ttgccttctt
     6241 ttttccgagt caaacactct ttctcaacca gacgagccaa aagtgtctga accgtggact
     6301 tggaccagtc aaaccgctct gccaaaaccc taatcaaatc tgtactggtc tgctccccct
     6361 gcatccaaat aatcttcatg acctgccatt ctgcatctga aatctgcatt accatacctc
     6421 caaaatctac atttgtcaat tacactcatc agtatactct taaaatctac atttgtcaat
     6481 tatagaaata atattttctt cgaaaaatag aattttaatc atttgaaaaa cgatttgcag
     6541 tcaaatatta ctatataaac aataaaaata tgctatacta aagaaaaaag aaaacaacca
     6601 ctaggggtgc gtaaagctga gattaacgac tgttagatcc ctctgactca atctagataa
     6661 tgctagctga tggaagtgga aatgataatg gggactagca gtcttctatt gcctttctaa
     6721 aacagactag cttgttctta agaatacaaa cttcagttgg ttgggaggtt ttagatgact
     6781 tatttacccg ttgctttgac cattgcaggg actgacccta gtggtggtgc tggcattatg
     6841 gcagatttaa agtcattcca agcgagagat gtctatggaa tggctgttgt aaccagtctt
     6901 gtcgctcaaa ataccagagg tgttcagcta atcgagcacg tttctcctca aatgttgaaa
     6961 gcccaattgg agagtgtctt ttctgatatt ccacctcagg ctgtaaaaac tggaatgttg
     7021 gctactactg aaatcatgga aatcatccac ccctatctta aaaaactgga ttgtccctat
     7081 gtccttgatc ctgttatggt tgctacaagt ggagatgcct tgattgactc aagtgctaga
     7141 gactatctca aaacaaactt actacctcta gcaactatta ttacgccaaa tcttcctgaa
     7201 gcagaagaga ttgttggttt ttcaatccat gaccccgaag acatgcagcg tgctggtcgc
     7261 ctgattttaa aagaatttgg tcctgagtct gtggttatca aaggcggaca tctcaaaggc
     7321 ggacatctca aaggcggaca tctcaaaggt ggtgctaaag atttcctctt taccaagaat
     7381 gaacaatttg tctgggaaag cccacgaatt caaacctgtc acacccatgg tactggatgt
     7441 acctttgctg cagtgattac tgctgaacta gccaagggca agagtcttta ccaggcagtt
     7501 gataaggcca aggcctttat cacaaaagct attcaagatg cccctcaact cggtcatggt
     7561 tctggtccag tcaaccatac aacttttaaa gattaagaaa aaaaactctc tagttcccac
     7621 tttaagggaa ttagagagtt tttatactct tcgaaaatct cttcaaacta cgtcagcttc
     7681 catctgcaac ttcaaaacac tgttttgagc tgacttcgtc agtcttatct aaaacctcaa
     7741 ggcagtactt tgagcaacct gcgactagct ttctagttta ctctttgatt ttcattgagt
     7801 attaattagg aaagaatgtc atgcaacttt gttaaaaagg cttgcgtttt tgcctcaata
     7861 tcttctgctt gcatcaaatc acgtacaaca gctacaccag ctatgccagt gtccataagc
     7921 tgatcaatat tctctgatgt caagccgcca atagcaacta ctggaatggc aaccgtttgg
     7981 caaattgttt tcaaggtcga tatcagagta atgggcgcat tttccttggt ggtggttggg
     8041 aaaatggctc ctgtacccaa gtaatctgca cctgatttct ccgcttccag agctctttta
     8101 accgttttag cggtgacacc gaggattttt tcaggaccca agactttgcg agctaccgaa
     8161 actggtaatt catcatctcc gatatgcaga cctgctgcat caaccgcaag acaaacatcc
     8221 aaccgatcat cgattatcaa gggtacctga taagcatctg ttatttcctt gacttgtttt
     8281 gccagttgat aatattgatt ggttgtgaga tttttttctc gcaattggac tatggtaacc
     8341 cctgaacggc aggccgtctc aacttttgca agaaagcttt ccacggaatc ttgatagcga
     8401 ttggttacca gatatagtct aagtgcttct ctattcataa acctctcctt tgatggtatc
     8461 tagccaattt tcatctcttc ttaggagcga aagctgattg agtacttggt aacgaaattc
     8521 ttccaatccc attccttgaa caactatttt ctcagcagcg atattgagat aagagactgc
     8581 taagcaagaa gcttcaaaac cagtctttcc ttggctgaga aaaacggctg ttaaggctcc
     8641 aaccaaatct cctgtccctg ttatccagtc taattctgca cagccattct caagtacagc
     8701 aacttgattc tccgaaacaa taaggtcctt gggacctgtg actaagaatg acataccagg
     8761 ataggtctga caccagtctt tcaagacttg aagcaaatcc tccgtttctt gatctttagc
     8821 actcgcatcg accccaacgc cgtgatgctt taatccaaca agacttcgaa tttctgacat
     8881 gtttccttta aggaccgtag gtctatagtc taaaaggtct ttaactaagc tcttacgaat
     8941 ggatgaagtc gttacgccaa ccgcatctac taccatcggg agagaagatt ggtttgcata
     9001 caaagctgcc atgcggattg ctttttcctt ctcagctgac aaatgcccca aattgatgaa
     9061 gagagcctgg ctttgcttag taaaatcaag aacttcacgg ggatcatctg ccatgacagg
     9121 tttgcatccc agagccaaaa tcccatttgc cagcatctca caagaaatct cattggtcat
     9181 acagtgaatg agggaactag agcctatagg aaaaggattt gtcaatgcct gcatcattct
     9241 atcctttcag caaagaaata tccttgcact tttttaaaga attcctgctt gattaaaaat
     9301 ctaaatgcaa taaaggaaat cgctgtacca atcaaggttg ctccgaaaaa tcgaggagtg
     9361 tagataaacc aactaagctt agcagccgat cctgtaaaga gcaccataac aggataggaa
     9421 acaatagaac caataatacc tgttcccaca atttctccca aggcagaaaa gtaaaatttt
     9481 cgaccgtact tataaaagag acctgctaga agggctccaa aagtcgctcc tgtgagagct
     9541 aaaggcggaa tcccttgagt cgtcatacgg ataaaggctg tcactgtagc catagccaag
     9601 gcataaacag gtcccatcat gattcccgct agaatattga ctacactgga catcggtgcc
     9661 attccctcaa tccgaaagat aggtgtaagg actacatcaa gggcaatcat catagataaa
     9721 atggtcaatt tgtgaacttg tagttggtgc tttctcatgt ttctattctt ctcctttttc
     9781 taaagactgt aaatcgctct tccatgtctg gtgttggtaa gccatctccc aaaacttggc
     9841 ttccatatga acactgatgt ggaaggcatc tagcattttt tgcttatctg tctcatcact
     9901 ttctcgatag agctgattga ccaatgctcc ctcctctctg atctgttgct ctaactcatc
     9961 cgtaatataa gtttcaatcc attgttgata gagaggattt ggtgatggtt taagattaag
    10021 tgatttgcct atatcatggt ataaccaagg acaaggaagc aagcttgcaa aagctatggc
    10081 taagttcggt tctgcaaatt gcctataaat atgagaaatg taatgataac aggttggagc
    10141 gattggatgt tgctccattt cctggtcgtt gatttccaat tccttgaaaa attgttggcg
    10201 aataaataac tcaccctcca ctaaaccctg agcattttgt ttcaagagtc ttttcatctc
    10261 ttggtttgaa gtcttatcag ccaaaagatg atagatttct gagaaaacct tcagatagta
    10321 ggcatcctga atcaggtaat agcggaaaat ggcaggttct aaattcccct cttgtaattg
    10381 taaaataaag ggatgatgaa aggaagcctg ccaagctttc ttggataatt ccatcgcaat
    10441 atctgtaaat tccataataa ctcctttata aaaatagact ggtttgaagc aataaaaaga
    10501 aaagcaggta gattaatttt gtttttttag gaatataaaa agtccgatag ctattcttca
    10561 actgtgcatg ttcgtcatat ccgtgagcag atagagctct caggtaaaga tggcgccacc
    10621 taaagactgt catcagaacc ttactgtaaa tcaagggcga ccaaaaatgt agttcttgac
    10681 cacgtaatag gcaagcttct ttgagggact tgatttcttg ctgaatgaga ggaaaagaat
    10741 tgaataccac aatcaaggca taggaccaag agcgtgatag ccccttttga gccaagtaca
    10801 agagaagctc ttttagtgaa atagaggaaa caaagacaag gccgatacaa actgtcacaa
    10861 aggccctcgt tccaagcatg actgcctgtg aagcatctcc gtgtaactga actgcccagt
    10921 agttggcaaa agatggtaaa atggcaagta tgatcatcca agctaacatt ttaaatcgac
    10981 ggtaatagag cataaagaga atacaaaatg cgactaccga aagattcaga gcaatcgaag
    11041 gaatgaaaga tgtttccaag gataaaatca gcaagaagag actgataatc ggtgtctggg
    11101 ttgctacttt gaccatacta tctcacctcc ccttgggtat tgctactctg agatgtaagt
    11161 ggtttggtaa tggtcacttc tttcacatgc cgaagaccct gactagtcat ctcaatccaa
    11221 taatcaacca cagaaatcaa agggtctaaa cgatgactaa tgagcagaaa acttcttcct
    11281 tgattcctct cctccacaat ccacttgcaa aaataatggc aggctctatc atccaaacct
    11341 gcaaaaggtt catctagcaa gatcacggaa gccttactgg tcaagatggt caggagctga
    11401 agaatttttt gctgaccacc acttaattga tagggactct tatcgactgc ctgctccaaa
    11461 tcaaaatatc gtaaagcttg aaaaatccgc tgatttcttt cagaatcagg tccatctaat
    11521 tgaagctcct ctcgcagact gactcggata aactgcttct cagcttcctg aacaacacca
    11581 gtcagatcac gatacaaact ctttttcttt ttcaggaccg aacccttcca tgcaatgcgc
    11641 cccttatact tttgaaattg aagaatagac cgaaagaggg ttgatttccc gacaccattg
    11701 tcacccagga tacaggaaat cccttgatag aatgtgaaat cagcaattga aaagaggggg
    11761 cgatttccaa actcacaagt cgttctatcc atatggaata gttccgggct agaagcaact
    11821 tcctttgaag caacctgtgt catctcatag gaagggattt ggaacacttc ccttagtttt
    11881 ccgtctctta gctcaaccat atggtcgata taggctttat agtcagataa atcatggtcg
    11941 cacaaaataa ctgtctttcc atcaagagcc aactctttta gaatctccaa tatctcgact
    12001 ctgctcttgc ggtcaatgga agcaaaaggt tcatccaaga gatagaccct aggattcatg
    12061 gcaaagagga cagccagcgc tgctttttgc ttttccccac ctgataggtg atgaatggga
    12121 cggtgtaaga ttgcctcgca acgacattgc tggacaacct ctgctatttt agaatcaatt
    12181 tcctgaaggt gatagccgat attctccaag gtgaaaatca gctcctcaaa caagctctcc
    12241 atggtaaatt gatgattggg attttgaaag agaatgccaa ccttctggac acgtgcgatg
    12301 atagaaagtt gactgacctc gctcccatct atcaggactt gaccactata gggaagagaa
    12361 ctgacttgag caatgacttg aaaaaggctg gattttcctg aaccactgct cccaactaac
    12421 aaggtaaagg cttgcgcatg aaaagtaaaa tcaaacggct cagagaagat tggggactga
    12481 atcgctcgta gttccagacc catctatgct tttcctccag ttgcaaactg atgatagagt
    12541 ttgacaatgg cacgaaccaa gatggtacag aagaaataaa cagaaataaa acgtaccaca
    12601 agtaaggaaa ggacaaacgg aagggaaaag gcgtagtaac ctaacttaat gtattcatag
    12661 acaaagctaa caagcgtaat cccaatacta ttagcagtta gagagagcca actttcatag
    12721 cgattcttag ttacgataaa accaaattca cttcccaaac cttgaaccaa gccagacaaa
    12781 agagctccta gaccaaattg gctaccataa aggacttcag caagcgcagc tagcacttct
    12841 ccaatcgttg cacttccgac tctcggaaca aagatggcag caatgggcgc agccatacac
    12901 cagagaccga agaggatttc attggcaaag gcctgcaaac caagaggtgt taagagtaga
    12961 ctgagaatat tatacacata tcctgaacca acgaaaaccc caccaaaaaa gatagacaag
    13021 aaagcaagca agataacatc ttttaactgc cattttttca acataaaaaa ctcctttttt
    13081 taaagaaaag tggggcactc aagaagaccg acctaaatac tttgtatagc agactgaatt
    13141 tagaacagta cacaagaatg ctaaaatatt tctagaaatt aatttgaatt ttctaattga
    13201 tttgttcgca tcttatttca atctactata tcatcttcat ccagtttcgt aaaagaaaaa
    13261 actctaatta cagatacgaa ttagagttca gcttacaaga ttagacagtt cttttcgaca
    13321 tacgaaaaaa acatttcaca tttcccttcg ccagtcttaa ctgtatcagg ttcaatgggt
    13381 atcatctcag cctaaagcac cccaaatgcc tttattattt aattatgtga ttattataac
    13441 acacatttta tactagttca agaaattgaa ctggaaatac agccttgcac tcacaaagac
    13501 agcagatctt tcttttgcaa aaaacaaatg acctgtttga tgaattagct attcaagctg
    13561 aatctagaca tagcttttta aaaaaggaaa atcctactta cttagaatcc aaggatagat
    13621 atctattgtt cactcatttc ccgaacagtt ttttctatat tttttgcata cgatattgcc
    13681 gaaatgattg aaacgccgtc aacattggtc ttcataatgt ctttaatatg tttcgtctgt
    13741 atcccaccaa ttgcaactaa gggcatttgt ggcaatagtt ttctcatcaa tttaacacct
    13801 tcataaccta tagcaccacc agcatcatcc tttgactggg tatcaaatac aggaccaaca
    13861 ccaacataat ctacatattc aacttttgat tgttgaaatt cttcctcgtt ttttatagaa
    13921 agaccaatta ttttatctgg catcaatttt ctaatttcat caacaccaat atcatcttga
    13981 cctacatgta cgccatcagc gtcaatttcc attgccaaat cgatatcgtc attaacgata
    14041 aacggcacat tgtatttttt acaaagttct ttaatttgga tagctagctc aagtttttct
    14101 aagccttcta aagcaccctc acctttttct cgaaattgaa ataaggttat accacctctt
    14161 aaggcttcct caacgactgt atatagattt tttccttggc aagtagtcgt tccacaaata
    14221 aaatatagtt ttagtaattc tttatgaaac atcttacttc actcttttga attcctttac
    14281 atcttcatct gtaatctcgt ataaggcatt tataaattca actttaaatg tcccaggaag
    14341 atgtccattt ggacgttttt ctgccatttc tccagcgata ttgtaaacca acattgctgt
    14401 ttctaatgat ttcaattctt gacctttttc tagtccgata aagcttgcta ccactgcccc
    14461 taataaacat ccagttccaa taacttttgg catcatggca ctaccattat gaatcgttac
    14521 cacttctcca tttaccgcaa tagcatccac ttcacctgtt actactattg gaatattgaa
    14581 cttctcattt gctgctagag caatctcgtc aatattatct actcccgcac tatctactcc
    14641 tttagatgcc acatctattc ctactaaaga ggcaatctct ccagcattcc ccctaatcgc
    14701 agctagtttg taattgttga ttaaatcatc tgctactttt tttctatatt ctcctgctcc
    14761 acaggctaca ggatctaaaa ctactgggac attatatttc tctgcaattt tcagagcagc
    14821 ttggtataat ttccaatttt catctgtcaa tgttcctatg tttattaata aaccaccagc
    14881 atactttaac aaatcctcta aatctgctgg aaactcactc atggctggtg aggcgcccag
    14941 tgctactaat ccatttgctg tgaaattttt tactacatca ttggttatac aaatgaccaa
    15001 tggtgctttt tcttttaata attttaaact tgtcatattg aaatccttcc ttttcacttt
    15061 atacgatcta ctgatttcga tttatttcta tctttcgtta agaatttttt tcatttacat
    15121 tgaatgattt atactcaatg aaaatcaaag agcaaactag gaagctaacc gcagattgct
    15181 caaaacactg ctttgaacct gtagataaga ctgacgaagt cagctcaaaa cactgttttg
    15241 aggttgtgga tagaactgac gaagtcagta accataccta cggcaaggtg aaactgacgt
    15301 ggtttgaaga gattttcgaa gagtcttacc tcatcaaatt tgtaaatatc atgagccttc
    15361 tctagacatc gtaaccaata tcaaaaaaag ctaattctaa agcgactgct tgattccatc
    15421 gttgctgaag ttctgtcaaa tcttctcgat ttttaccgac acgattgagt tcgtcaacca
    15481 gaaattgaac ccactctgca aagaaaggac ctctgtggag attgatccat tccgaatgaa
    15541 tatagacttc aggtagagcc aaatctttag aaccccagtc taaatagaga ccttctgcaa
    15601 tgaccagcat aaccaaaaga tgggcatagt ctgatgaagc cactgcccaa tacattagat
    15661 cctgaaaggc ttttgttaca gggtgcaaag tcacttctag atagtcattc tctgctactt
    15721 ttaactcttt aaaagccttt tggaaataac catcttcatc tgcttcaaga aagcctagtt
    15781 gcttggcaaa acgaagcttg gattcaagtt tatctgcgtg agctacgcag gcacccagca
    15841 tggataagaa ggcatcaaag aagtgataat cttgaatcag atagtccttt aagaccttat
    15901 tctcaattgt ccccgcaaaa agttccttaa caaaacgatg attgattgca gcctgccaat
    15961 ccttctgact gctttttaat aattctccaa cagtcaaacc tggctgaaat gcatagtctt
    16021 gtgtttccat atttacttct cctctcttta cttgttagta attaataaaa caccaagaaa
    16081 tatcaagcaa aatcgtaatt ccacttgatc cttttaaaac acatcgagag tatttgcaga
    16141 gagctaacta aacaagccta tccagtttat ataaacaaaa aactccaatt acaatcaaga
    16201 attagagttg acttacaaga ttagaccgtt catttcacca tacgaaaaaa ctgttcacat
    16261 ttcccttcgc cagtcttaac tgtatcaggt tcaatgggta ttatctcagc ctaaagcacc
    16321 ccaaatgtct ctattattta attactgaac cagtatagca aaaaatgaaa gccttagcaa
    16381 gatatttaac cgaaaaatat ctttatatat agtagattga aactagaata gtacccctct
    16441 acttctaaaa cattgttaga aatcgattta aatatcctga ttgatttgtc ctgtttttat
    16501 tccattttac tatggttttc gatagcgatt tattcttcca atacacgaag aaaaacctcc
    16561 acattcagtg gaggcaatct gttttatcaa tacaatttta agtcacgagg gtcaactggg
    16621 aaggttgggt tgtatggatt gtgacggagc ttaaagtgtt tgacatcttc aatggtctga
    16681 gctccagaca attgcataac tgtcttcaat tccgcattca agtgttcaaa gacttgacgc
    16741 acaccgacac taccaccgag agccaagcca taaataaccg ggcgaccaat agctaccaag
    16801 tctgctcctg aagccaaggc tttaaagacg tgttgaccac gacgaacacc agagtcaaag
    16861 acaatcggca cacgtctatc aactgcttct gccacttctt gaagcgagtc aaaggcagct
    16921 ggtccaccgt cgatttgacg accaccgtgg ttggttaccc agataccaga agctcctgca
    16981 gcaagcgaac gttcaacgtc ctcacggcat tgtggtccct tgacatacac aggaagtcct
    17041 gagtattcag cgataaattc tacatcacgt ggagacaagc gttgtttagc tgatttgtaa
    17101 acaaagtcca ttgatttacc agcaccttct ggcaggtatt cttcaacaat cggcatgcca
    17161 actgggaaga caaaaccatt acgcttatcc acttcacgat tcccccctac agtagcatct
    17221 gccgtcaaga caatcgcttt ataaccttca gccttcacac gatccatgat gtggcggttg
    17281 ataccgtcat ccttactaaa gtaaaattgg aaccaatggg gtgtcccttg aagggcttca
    17341 gaaatctctg gaaggtcaac agtagagtaa gaactggttg tataaagaga accaaactca
    17401 tgcacaccac gcgcagtcgc cacttccccc tgttcattcg ctaatttatg ggccgcaaca
    17461 ggcgccataa tgattggtga agatagtttt tcacctgcaa attcaatctc tgtacttgga
    17521 ttttcaacat cgcaaagtgt atgaggaacg atgagtttgt ggttaaaggc gcggatattc
    17581 tctcttaaag tgaaagtatc ttccgcccca ctagcgatat agccaaatgc tgctttagga
    17641 ataacttgtt gcgccattgg ctccaaatca taggtattga tgaagtctac atgaccttct
    17701 gcattgcttg ttttgtatga cataaaatgc cctccttgat taagtaagcg tttgcttttt
    17761 actacacaac tataataact cttttttcaa tcattttcaa gagttttgct taaaaaccat
    17821 cttatttttt catacaatat actagcccta ctttccttaa actctaaact ttagtctata
    17881 ttaagtgaat cgttgagatt ttttgctgcc aggcatttga actacttttt tatttgcgga
    17941 ttctatctac taatactata aaaaaacaag tgaataagac accagaacat cctctaatag
    18001 gacctatgga cttatatcag tcccatatat actgtttaag caagatacta tcctagttga
    18061 cgctaacttc ctatcccact tattaatttt ttatttatag tgaatctgaa caaatcaatt
    18121 ggggaatcca agtcaatttc tagtactttt tgaacagttt cagcgtacta tcgtaaaatg
    18181 aaataaaaca tgcacaaatt gcttagggaa tttaaaccaa tttctaacaa tgtcttagaa
    18241 atcaaagtgt actatttcaa cttcaatata ctacacttca ttttctcctt aaattcagtc
    18301 tctttttgaa tcaaaaaatc ccctggtaag agccagagga taagaattta tttcattgtt
    18361 gggaagagca atacatcacg gatagttgtt gtatcagtga ggagcatgca gagacggtcg
    18421 ataccgattc ccaaaccacc tgttggtggc ataccgtatt caagagcttc aatgtagtca
    18481 tagtcgattc ctgtcgcttc atcatcacca agttctttgg ctttagcttg ggcttcaaaa
    18541 cggctaagtt ggtcgattgg gtcgttcaac tcagtaaagg cattaccgta ctccttagtc
    18601 atgataaaga gctcgaaacg gtcagtaaag cgttggtctt caggattttt cttagcgagt
    18661 ggagatacag ctactggatg tccatagaca aaggttggtt ggattaaagt ttcttcaaca
    18721 aactcttcaa agaaggcatt gatgatgtga ccaacctcag tgtagtgttt ctcaactgga
    18781 actttcttct cagcagcgat agctttagct tcttccaaag tcatgtcttg ccagaaatcg
    18841 acaccagtaa tttctctgat agcatccacc atatgaacac gcttaaatgg ttcgttaatc
    18901 ttgatttcag taccttggta gttgactggg ccatcacctt tgactgattt agcagcgtgt
    18961 tggataatgc cttcagtcaa gtccatgatg tcttggaagt ctgcataagc ttggtaaact
    19021 tcgatagaag tgaactcagg gttatgagta gcgtccattc cttcgttacg gaagatacgg
    19081 ccaatttcat agacacgttc cataccaccc acgataaggc gttttaagtg aagctcagtc
    19141 gcgatacgaa gcaccatgtc aatgttttgg gcattgtggt gggtgataaa tggacgggca
    19201 gcagcaccac cggcttcatt atgaagaaca ggtgtttcca cttcaaggaa tcctttttgg
    19261 tcaaggtaac gacggatttc agagatgatt tttgaacgag tgacaaagcg ttcaaagctt
    19321 tcacgattag aaatcaagtc aaggtaacgt ttacggtaaa ttgtttcaac gtctgtcaaa
    19381 ccatggaatt tctcaggaag aggacgaaga gccttagaca agtgtgtgat gtgggttgcc
    19441 ttgatagaga gttctcccat atccgtacgc atcacttcac cttcgacacc aaggaagtca
    19501 ccaaggtctg cttttttgaa gatttcgtag ttttcttcac cgacagcatc cttacgaacg
    19561 tagatctgaa tctggccttc gcggtcttga aggtgggcaa aaccaacttt tcctttacca
    19621 cgtttggtta ccaagcgtcc tgcgatagta gctgtttcgt ttttatcgtg taattgttct
    19681 ttatcgaggt tggcatattt atcttttaat tcttgtgaat ttgcagtacg ttcaaaacgt
    19741 tttccgaaag gatcgattcc ttgttcgcgg agcgcagcca ttttttcacg gcgaacgatc
    19801 tgctggtcat ttagttcttc catatgttct gtagacatgg gatcctccta gttttactca
    19861 aaattgaata cgatgagtca ttttttgcga tactcccatt ttatcataaa taagcaagaa
    19921 attcacggat aatctttaaa aactaaaaag aacctgacgc taaaatcact ggaaagaagt
    19981 gaaagtatct tccgccccac tagcgatata gccaaatgct gctttaggaa taacttgttg
    20041 cgccattggc tccaaatcat agg
//
LOCUS       DAVLHB010000040        19731 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLHB010000040 DAVLHB010000000
VERSION     DAVLHB010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19731
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.040"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..388
                     /locus_tag="VXE36_001562"
     CDS             <1..388
                     /locus_tag="VXE36_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEV0779830.1"
                     /translation="NILIDNRNNIYIIDFEHALRKETQIEEKKLPLFGTPGFYETNLN
                     LLNNQPEDIMGLVLLLYWSQNLDDFNVFSKMSFLEAMEYAMNFNSRRLDTLDKSDWLY
                     DIYKKAFNYKYDTFSELKKDFIEVLK"
     gene            402..1319
                     /locus_tag="VXE36_001563"
     CDS             402..1319
                     /locus_tag="VXE36_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779831.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            1316..2116
                     /locus_tag="VXE36_001564"
     CDS             1316..2116
                     /locus_tag="VXE36_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779832.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            2274..2747
                     /gene="tnpA"
                     /locus_tag="VXE36_001565"
     CDS             2274..2747
                     /gene="tnpA"
                     /locus_tag="VXE36_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEV0779833.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            3004..3225
                     /locus_tag="VXE36_001566"
     CDS             3004..3225
                     /locus_tag="VXE36_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0779834.1"
                     /translation="MYRRLRDLREDHDLPQKQIATILSFTNSAYAKIERGEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            3672..3974
                     /locus_tag="VXE36_001567"
                     /pseudo
     CDS             3672..3974
                     /locus_tag="VXE36_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            4130..5359
                     /locus_tag="VXE36_001568"
     CDS             4130..5359
                     /locus_tag="VXE36_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0779835.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5379..8075
                     /gene="ppc"
                     /locus_tag="VXE36_001569"
     CDS             5379..8075
                     /gene="ppc"
                     /locus_tag="VXE36_001569"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0779836.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYETIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    8158..8375
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8488..9492
                     /locus_tag="VXE36_001570"
     CDS             8488..9492
                     /locus_tag="VXE36_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0779837.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            9561..10427
                     /locus_tag="VXE36_001571"
     CDS             9561..10427
                     /locus_tag="VXE36_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0779838.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10424..11182
                     /locus_tag="VXE36_001572"
     CDS             10424..11182
                     /locus_tag="VXE36_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779839.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            11272..13032
                     /gene="dnaG"
                     /locus_tag="VXE36_001573"
     CDS             11272..13032
                     /gene="dnaG"
                     /locus_tag="VXE36_001573"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0779840.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDDNQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            13035..14144
                     /gene="rpoD"
                     /locus_tag="VXE36_001574"
     CDS             13035..14144
                     /gene="rpoD"
                     /locus_tag="VXE36_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0779841.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            14158..14487
                     /locus_tag="VXE36_001575"
     CDS             14158..14487
                     /locus_tag="VXE36_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0779842.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14602..15645
                     /gene="cpoA"
                     /locus_tag="VXE36_001576"
     CDS             14602..15645
                     /gene="cpoA"
                     /locus_tag="VXE36_001576"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0779843.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            15661..16986
                     /locus_tag="VXE36_001577"
     CDS             15661..16986
                     /locus_tag="VXE36_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0779844.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            17017..17193
                     /locus_tag="VXE36_001578"
     CDS             17017..17193
                     /locus_tag="VXE36_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0779845.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            17252..17386
                     /locus_tag="VXE36_001579"
     CDS             17252..17386
                     /locus_tag="VXE36_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0779846.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17450..18760
                     /gene="obgE"
                     /locus_tag="VXE36_001580"
     CDS             17450..18760
                     /gene="obgE"
                     /locus_tag="VXE36_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0779847.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18770..18928
                     /locus_tag="VXE36_001581"
     CDS             18770..18928
                     /locus_tag="VXE36_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779848.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(18979..>19731)
                     /locus_tag="VXE36_001582"
     CDS             complement(18979..>19731)
                     /locus_tag="VXE36_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0779849.1"
                     /translation="IAQDFEKLDIITVLEGRTQAVIRDHFLKYDRAVRCRVKIITMDM
                     FSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVHVQIMNQFHRKSHEYKAIKRYWK
                     LIQQDSCKLSDKRFYRPIFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEP
                     EKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLIKLIKRN
                     AFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         6140 a         3316 c         4292 g         5983 t
ORIGIN      
        1 taatatactt attgataata gaaataatat ttatattata gactttgagc atgccctaag
       61 gaaagaaact caaattgaag aaaaaaagtt gcctctattt ggaactccag ggttttatga
      121 aaccaactta aatttattga ataatcaacc agaggatatt atgggattgg ttttgttatt
      181 atattggagt cagaatttag atgattttaa cgtcttttca aaaatgagtt ttttagaagc
      241 gatggagtat gcaatgaatt ttaattcgcg tcgcttagac acacttgata aatcagattg
      301 gctttatgat atttataaaa aagcgttcaa ttataaatat gatacttttt ctgaattaaa
      361 aaaagatttt atagaggtat taaaataaag gtaggggtgt tatgaattgt ttcttgaaaa
      421 tgaataatgt aagtgttcgt tatgatgacg taatagcttt aaaagatata actttacaaa
      481 taaataaggg agatttcatt ggcttattag gttcaaatgg tgcaggtaaa tctacgttaa
      541 ttaattctat tgtaggtttt caagagattt atttaggaga aatagagtat tgtgataaag
      601 atttgatagt tagttctcaa ccttttgctc atttaggctt tactcctcaa accacagtaa
      661 ttgattttta tactactgtg aaggacaatg taatattggg gctgaacctt gctggaaagt
      721 ttgggaaaaa tgctgagaag ttgtgtcaaa tagccttaga aattgttggg ttagctgata
      781 aaaaaaataa tttggtagaa acattgtcag gtggacaact gcaacgcgtc cagattgcta
      841 gagcaatagc tcataatcca gatttttata ttttagatga acctaccgtt ggtttagata
      901 ctgaatctgc cgaaaaattt ttaatgtatt taaaagataa gagtttggaa ggaaaaacta
      961 ttatcatatc ttcacatgac ataaatctac tcgaaaagtt ttgtaaaaaa atactttttt
     1021 tacaaaatgg ctccatatca ttttttggtg atatgcgtga ctttgtagat aattcaacta
     1081 tcaaattaaa tttttcaatg cagaatagaa tttctagata tcaaattgaa tttttagaaa
     1141 attttagatt taaagttcac atcgaagata atgatagttt tacaatagaa gtccctatag
     1201 aagaaaatat cttagatgtt atcaatgagg taggaaaagc atgtgaaatt aaaaactttt
     1261 caacaagtaa attaacctta caagaaagtt atttgcaaag aataggagga gaaaaatgaa
     1321 ggctgatcaa ttaaggcaca aatcggactt aggtttaaga ggtctagcga ttattgctaa
     1381 aaatgagatt attgcttttt ttagaagtaa aggtttaatt atttctcagt ttctacaacc
     1441 aatcttatat gttgttttta taataatagg attaaattct tcgataaaga acattcagtt
     1501 taatgatata aaaacctctt atgcagaata tacaatcatt ggtgttatag ctttattgat
     1561 aatcgggcag atgactcaag ttatttatag ggtgacaata gataaaaaat atgggctact
     1621 tgctcttaag ttatgcagtg gagttcgtcc tttatattat attttaggga tgagtatcta
     1681 ttctatatta gggttgatag ttcaagaaat tattatatat ataattacgt tagcgtttga
     1741 gataaatatc gcaatggata gattttttta tacagttttg ttatctattg ttgttttatt
     1801 attttgggac tcccttgcaa ttttacttac aatgtttatc aatgattaca gaagacgtga
     1861 tattgtaata cgttttgtac taacaccgct tggttttaca gctcctgttt tctacttaat
     1921 agattctgct cctagtattg tgagatggat tggtcagtta aatcccttaa cttatcaatt
     1981 aactattttg agaaactttt attttaaaaa ttcaacaact ttggaattag ttttcttatt
     2041 gttaacatca ttacttgtcc ttatatctgt atcttttatt ataccaaaga taaaattgat
     2101 actgatagaa agataaaagt tgggtcatcc aacttttttg ttgtctcccg aaaaccacta
     2161 gctatgctag tggttccata gagcttttag cgtggtaaca aaaagaacct cctaaaatga
     2221 taagatagaa gtggtttctc cgccactaca acatatcata caggaggtac ctcatgagag
     2281 aggataatca aagtttatca cataccacat ggaattgtaa atatcatatt gtttttgcac
     2341 ccaaatatcg tcgtcaaatc atttatggca gatacaaagc tagtatcgga agaatcatac
     2401 gtgacttatg tgagcgtaag ggtgtaataa tccatgaagc gaatgcttgt tcagaccata
     2461 ttcacatgct tatcagtatt cctccgaaac ttagtgtttc gtcctttatg ggctatttaa
     2521 agggcaagag cagtttgatg atttttgata agcatgcgaa tttaaaatac aaatatggca
     2581 atcgcaagtt ttggtgtaga ggctattatg tagatacggt aggccgtaat cagaaagtga
     2641 tagctgaata tattcagaat caattacaag aagacagagt agcagaccag ctcacgttat
     2701 tcgagtcagt agatccgttt actggcgaaa taaataagag gaagtaacta aggtgcttta
     2761 gcacctgctc gggaaagtgg tgcgcgagga agctatttcg gtgggccttt ggccctggcc
     2821 ggtagaagcg gcttatagcc gcagaacaaa ccaccagttc acactggtgg ttttgattta
     2881 aaaaacttga tacataaaaa taaaagtcta tataaaggat ggtaaaattc ctgttgtccg
     2941 atttggacaa tatcctaaat agttacaata tatggtctat actttttctt aggagaaagc
     3001 tagatgtaca gacgtttgag agatttgagg gaggatcatg atctgcccca aaagcaaata
     3061 gctacaatac tttcgtttac aaattcagct tatgccaaaa ttgaacgggg tgagcatgcg
     3121 ttgacggctg atgtattggt taaactctca gatttctatg acgtcagtac agactattta
     3181 ttgggattaa ctgattttcc tgataaaatt cgctttagaa aataatctcc tcaatttcat
     3241 agagtttgaa aatgagtgag attttttatt tgccctttga caactgaata gcctaaaatg
     3301 gtactttcct catttgtgga gcaaatttga atggctcgcc atgataagag cgattttaaa
     3361 accatcaata aaatagagcg atactttata tgccatgata caaatgatat acaatgatac
     3421 ttctgaccgt tcagcctgcc aacgtaaaag agcagcaagt gaaattctta tgatgacttc
     3481 atcagtcatg ccacgttgaa tgtgtgagtt tgttagataa acgcaattaa tcctcaaaag
     3541 gttccccgaa ccttttgagt tctacagacg catcacgtgg agtgtgtaag cttgttgcta
     3601 aaagcgtaaa aaccttggaa cgaaaggaat aatagacttt ctgcgaaaca aaaatataat
     3661 acaataaaac tatgaatgat gaagcaagta aacaattgag cgatagccgt ttcaagatcc
     3721 ttgtaggtgt tcagcgcacg acttttgaag agatgttagc tgtgttaaaa acagcttatc
     3781 aacgtaaacg cgcaaaaggt ggacgaaaaa gcaaattaag cctagacgat ctccttatgg
     3841 taactattca atacatgcga gaatagagca cttatgaaca aattgcggct gattttggca
     3901 ttcacgaaag caacttaatc cgtcggagtc aatgggttga agcaactctt attcaaaatg
     3961 gttttacgat ttcaaattct gccttaattc tgtaaaaaca gtaaaattcg aaggattgta
     4021 aggtaagagt ttttttcttt ctgaaaaaat ggtataatag caatcaaaac tagaaaataa
     4081 aacggaattt ggaacagatt tgtctgtatc ctagtagagt ggtgatacta tgaagattag
     4141 taagaggcac ttattaaatt attccatctt gattccctac ttgcttttat ctattttggg
     4201 cttgattgtg gtctattcga ccaccagtgc tattttaatt gaagaaggca agagcgcctt
     4261 gcagttggtt cgaaaccaag gaatcttttg gattgttagt ttgatactga ttgccttaat
     4321 ttataaattg agactagatt ttttgagaaa tgagcgacta atcattttag ttatattaat
     4381 agaaatgctt ttattgttct tggctcgttt tattggtatt tccgtaaacg gggcatacgg
     4441 ttggatttcg gttgcaggaa taactattca gccagctgag tacttaaaaa tcattattat
     4501 ttggtattta gctcaccgat tctccaaaca gcaagaagaa atagctactt atgattttca
     4561 agttttgact caaaatcaat ggcttccccg tgcttttaat gattggcgat tcgttctcct
     4621 agttctgatt ggaagtttgg gaattttccc tgatttagga aatgcgacta ttttagtctt
     4681 ggtttccttg attatgtata cagttagtgg aatcgcttat cgctggtttt caaccattct
     4741 ggcgctcgta tctgccgctt ctgtctttgt cttgaccact atcagcctaa tcggtgttga
     4801 gaccttttca aaaattccag tattcggcta tgtagccaag cgctttagtg ccttttttaa
     4861 tccttttgcc gatcgtgctg atgcaggtca ccagttagct aattcttatt ttgccatggt
     4921 caatggcggt tggtttggtc taggtcttgg aaactcgatt gaaaaacgag gttatttgcc
     4981 agaagctcat acagactttg tcttttctat cgtgattgaa gaatttggct ttgttggtgc
     5041 cagtcttatt ttagctctct tgtttttcat gattttgcgg attatcttgg tcggtatccg
     5101 agcggagaat cctttcaatg ccatggttgc actcggtgtc ggagggatga tgttggttca
     5161 ggtatttgtc aatatcggag ggatttcggg cttgattcca tctacaggag tgactttccc
     5221 cttcttatcc cagggtggaa atagtcttct agtcttatca gtggcagtag cctttgtctt
     5281 aaatattgat gccagtgaaa aacgcgctaa attgtaccga gaattggaaa atcaaccaat
     5341 gaaccttctg ttgaagtagg ataaagaaag gatagtttat gtctcttcaa aaattagaaa
     5401 attatagtaa taaaagtgtt gtgcaagaag aagtcttgat tctaacagaa ttactggaag
     5461 atattactaa aaatatgctt gccccagaga cctttgaaaa aataatacag ttgaaagaat
     5521 tatcaacgca ggaagattat caaggtctaa accgtctagt gactagctta tcaaatgatg
     5581 aaatggtcta tatttcacgc tatttctcta tcttgcctct tttgattaat atttcagagg
     5641 atgtggattt agcttatgaa atcaatcatc aaaataatat tgatcaggac tatttaggta
     5701 aattatctac aacgattaaa ttggtagcag aaaaggaaaa tgccgttgag atcctagaac
     5761 acttgaatgt tgtccctgtt ttgacagccc atccaacaca agtgcaacgc aaaagtatgt
     5821 tggatttaac aaatcatatt catagtcttt tgcgtaaata ccgtgatgtt aagttggggt
     5881 tgatcaataa agataaatgg tacaatgatt tgcgtcgtta catcgaaatt atcatgcaga
     5941 cagacatgat tcgtgagaaa aaattaaaag tgactaacga aatcacgaat gctatggaat
     6001 attataacag ctcctttttg aaagctgtac ctcatttgac gacggagtat aagcgcttag
     6061 cgcaagcgca tggtctgaat ttaaaacagg ctaaaccaat caccatgggt atgtggatag
     6121 gtggtgaccg tgatggaaat ccatttgtta cagcaaagac cttgaagcag tctgcactca
     6181 ctcagtgtga agtcatcatg aactactatg ataaaaagat ttaccaactt tatcgtgaat
     6241 tttctctttc aactagcatt gtcaacgtca gcaagcaagt cagagaaatg gctcgtcaat
     6301 ccaaggataa ctcgatttac cgcgaaaaag agctttaccg tcgtgccttg tttgatattc
     6361 aatcaaaaat tcaggcaact aaaacctatc tgattgagga tgaagaagtt gggactcgtt
     6421 atgaaaccgc caatgatttc tacaaggatt tgattgccat tcgagattct ctactagaaa
     6481 ataagggcga gtccttgatt tcaggtgatt ttgtggaatt attgcaggca gtagagatat
     6541 ttggttttta cttagcatca attgatatgc gacaagactc tagcgtctat gaagcctgtg
     6601 tggcagaact cttgaaatca gcaggaattc attctcgtta tagcgagttg agcgaagaag
     6661 aaaagtgtga ccttctcttg aaagaattag aagaagatcc ccgaattctt tctgcgactc
     6721 acgcagaaaa atcagaatta ttagcaaaag aattagctat ttttaagacg gctcgtgttt
     6781 tgaaagataa gttgggagat gatgtcatcc gtcagaccat catttcacat gcaaccagcc
     6841 tttctgatat gctagaatta gctattctgt taaaagaagt aggactggtg gatacggaaa
     6901 gggcgcgtgt tcagattgtt cccctttttg aaacaattga agacttggat cattcagagg
     6961 aaacaatgag aaaatatctt tctcttagcc ttgccaaaaa atggattgac tcacgaaata
     7021 actaccaaga aatcatgctt ggctactctg acagtaataa agatggcggt tacttgtcat
     7081 catgttggac cctctacaag gctcaacaac aattgactgc tattggagat gaatttggcg
     7141 ttaaggttac cttcttccat ggtcgtggtg gtactgtcgg tcgtggtggt gggccaacct
     7201 atgaagccat tacatctcaa ccgctcaagt ctatcaagga tcgtatccgc ttgacggagc
     7261 agggtgaagt aattgggaat aaatacggta acaaagacgc cgcttactat aaccttgaaa
     7321 tgctagtatc ggcagctatt aaccgtatga ttactcagaa gaagagcgat accaataccc
     7381 caaatcgtta tgaaaccatt atggatcaag tagtggaccg tagttacgat atctaccgtg
     7441 atttggtctt tggtaatgag catttctatg attatttctt cgagtcaagt ccaatcaagg
     7501 ctatttcaag ttttaatatt ggttctcgtc cagccgctcg taagactatt actgaaatcg
     7561 gtggtttgcg tgccatccct tgggtattct catggtcaca gagtcgtgtt atgttccctg
     7621 gatggtacgg ggttggttca agcttcaagg aatttatcaa taaaaatcca gagaatattg
     7681 ctatcttacg agatatgtac caaaattggc ctttcttcca atcgcttctt tcaaatgttg
     7741 atatggtttt gtcaaaatca aatatgaata ttgcttttga atatgctaaa ctttgtgaag
     7801 acgagcaagt taaggccatc tatgagacta ttttaaatga atggcaagtt actaagaacg
     7861 ttatcttggc tattgaagga catgacgaac tcttagctga caatccatat ctaaaagcta
     7921 gtctggatta ccgtatgcct tactttaata ttctcaacta tattcagttg gagttgatta
     7981 aacgccaacg tcgtggagaa ttgtccagtg atcaagaacg attgattcat atcaccatca
     8041 acggaattgc gacaggattg cgtaattcag gttgataatt ttcaagagtg aatgctaaaa
     8101 gtgaatatca aaaaaattct aatagactat tgacaagtag tttaaaaatg atataattta
     8161 accattcaga aaagtaatca tacaaacttt ttagagagtc tgtggtagct gaaaacagat
     8221 aagtggcaat gatgaaaatt gggctgaatg ctatttagaa tttgaaatta taaaaattcg
     8281 gtaagcacac cttacagtgc atctcgttat tgcgagactg agcgataggg aaattcccta
     8341 taattgaggt ggtaccgcgc atcgacgtcc tcacacaagt tttttgtgtg aggatttttt
     8401 tgatggaggt tagtatggaa agaaaacgat ggcgtcgctt gtttagataa gtgaaatatg
     8461 ttaaaggaaa taaaaaggag aaacagaatg aaaaataaac gtttaattgg aattattgct
     8521 gcattagcag tcttagtagc aggaagcttg atttattctt caatgaataa atcagaagct
     8581 cagaataata aggatgagaa gaaaataacc aagattggtg tgcttcaatt tgtgagccat
     8641 ccatcccttg atttgattta taaagggatc caagatggac ttgcagaaga aggatataaa
     8701 gatgatcaag ttaaaattga ttttatgaac tcagaaggtg accaaagtaa ggttgcgaca
     8761 atgagtaaac aattggttgc aaatgggaat gaccttgtgg ttggtatcgc aacaccagca
     8821 gcccaagggt tggctagtgc aacaaaagac ctaccggtta tcatggccgc tattacagac
     8881 ccaattggtg ctaacttggt taaagatttg aaaaaaccag gtggcaacgt tacaggggta
     8941 tctgaccaca atccagctca acaacaagtt gaactcatca aggctctgac accgaatgtg
     9001 aaaacaatcg gagctcttta ctcaagtagc gaagacaatt caaaaacaca ggtcgaagaa
     9061 tttaaggctt atgctgaaaa agcaggtctg acagtggaaa catttgcagt tccttcaaca
     9121 aatgaaattg cctcaactgt cactgttatg actagcaagg tagatgctat ttgggttcca
     9181 attgataaca ccattgcatc aggatttcca acggttgtct ctagcaatca aagttctaag
     9241 aaaccaattt atcccagtgc gacagctatg gtagaagtag gtggtttggc atcagttgta
     9301 attgaccaac atgaccttgg tgtggcaaca ggtaaaatga ttgtgcaagt cttgaaaggt
     9361 gcaaaaccag ccgatacccc agtcaatgtc ttttcaactg gtaagtcagt catcaataaa
     9421 aaaatagcac aagaactagg tattactatt cctgagtctg ttctcaaaga agcaggacaa
     9481 gtcatcgaat aaataaggta gggaggagga gactcttccc attttttaaa aagatgaata
     9541 tagaaaggat taaataaaat atgattgttt ccattatttc tcaaggattt gtctgggcta
     9601 ttctaggtct gggaatcttt atgacattta ggattttaaa ctttccagat atgacgacag
     9661 aaggttcctt ccctcttggg ggagctgttg ctgtcacttt gataaccaaa ggcgtgaacc
     9721 catttttagc gacacttgtt gctgtaggag caggttgttt ggctggaatg gcagcaggcc
     9781 ttctttatac aaaagggaag atcccaacct tgctctcagg gattttggtg atgacttctt
     9841 gtcactcaat catgctcttg attatgggac gtgcgaattt aggcctgctt ggaaccaagc
     9901 aaattcagga tgttttgcct tttgattcgg atttgaatca actcttgaca ggtctcatct
     9961 ttgtgagtat tgttattgct ctcatgctct ttttcttgga cactaaactc ggacaagcct
    10021 atattgctac aggggataat cctgatatgg ctagaagttt cgggattcat actggacgca
    10081 tggagctcat gggcttggtc ttatcaaatg gtgtgattgc ccttgcaggt gccctcattg
    10141 ctcagcaaga aggttatgcc gatgtgtctc gagggatcgg ggttatcgtt gtggggcttg
    10201 caagtttgat tattggagaa gttattttca agagtttgag cttggcagag cgtttggtta
    10261 ctatcgttgt aggttctatc gcttatcaat ttttagtgtg ggcagttatc gcacttggct
    10321 ttaatacaag ttaccttcgt ttatacagtg ccttgatttt agcagtctgc ctcatgattc
    10381 caacatttaa gcaaacaatc ttgaaaggag ccaagttaag caaatgacag caattgtaga
    10441 attaaaaaat gcaaccaaaa tcgttaaaaa tggctttgat gaagaaaaga ttattttaaa
    10501 tgatgtttcc ttagaaattt ttgaacggga ctttatcacg attttgggcg gaaatggtgc
    10561 tggaaaatca actctcttta acactatagc agggacctta tcactaacta gtggaactat
    10621 ccgtatttta ggtgaagatc tcactaagtt ttcacccgag aagcgtgcca agtacctgtc
    10681 tcgtgtcttc caagatccaa agatggggac agctccccgt atgacggtcg ctgaaaatct
    10741 tttaatcgcc aagtttcgtg gtgaaaagcg tggattgtta ccacgacgct tgactagcta
    10801 taaggatgaa tttcaggcaa ccattgaaaa agtaggaaat ggtcttgaga aacacttgaa
    10861 tacaccgatt gagttcttat caggtggaca aagacaggct ttgagtctct tgatggcaac
    10921 cttgaagcga cctgaattac tcctgttaga tgagcatact gctgccctgg atccaaagac
    10981 tagtgttgct ttgatggaat tgacagatga atttgttaag aaagatcagc taacagccct
    11041 tatgattact catcatatgg aagatgctct caaatacggc aatcgcttga ttgtcatgaa
    11101 agaaggacgg attatccaag atttaaacca agaagaaaaa gcaaaaatga aaatctctga
    11161 ttattatcaa ctctttgaat aaagtaggga aaatgagtga aatggtttac tttttttctg
    11221 aaataaagta tactatataa agtaaactat gataacatgg aggtattgtg tatggttgac
    11281 aaacaagtca ttgaagaaat caaaaacaat gccaacattg tggaagtcat aggagatgtg
    11341 atttctttac aaaaggcagg acggaactat ctagggctct gtccttttca tggtgaaaaa
    11401 acaccttctt tcaacgttgt agaggataag cagttttatc actgtttcgg ttgtggtcgc
    11461 tcaggtgatg tctttaagtt catcgaggag taccaagggg ttccctttat agaggcagtc
    11521 caaatcttag gtcagcgtgt tggaattgag gttgaaaaac cgctttatag tgagcagaag
    11581 ccagcctcac ctcaccaagc tctttatgat atgcacgaag atgcagccaa attttaccat
    11641 gcgattctca tgacaacgac tatgggcgaa gaggccagaa attaccttta tcagcggggt
    11701 ttgacagatg aagtgcttaa acatttttgg attggtttag cacctccaga acgaaactat
    11761 ctctatcaac gtttgtctga tcagtatcgt gaagaggatt tactggattc aggcctgttt
    11821 tatctctcgg atgacaatca atttgtagac acctttcaca atcgcattat gtttcccctg
    11881 acaaatgacc aaggaaaggt cattgccttc tcaggtcgta tctggcaaaa aacggattca
    11941 caaacttcta agtataaaaa cagccgatcg actgcaattt ttaacaaaag ttacgaatta
    12001 tatcatatgg atagggcaaa aaaatcttct ggaaaagcta gtgagattta cttgatggaa
    12061 ggattcatgg atgttattgc agcctatcgg gctggaatcg aaagtgctgt ggcgtcgatg
    12121 ggaacggcct tgagtcgaga gcatgttgag catctgaaaa ggttaaccaa gaaattggtt
    12181 cttgtttacg atggagataa ggctgggcaa gccgcgacat tgaaagcatt ggatgaaatt
    12241 ggtgatatgc ctgtgcaaat cgtcagcatg cctgataact tggatcctga tgagtatcta
    12301 caaaaaaatg gtccagaaga cttggcctat ctattaacga aaactcgtat tagtccgatt
    12361 gagttctaca ttcatcagta caaacctgaa aacagtgaaa atctgcaggc tcagattgag
    12421 tttattgaaa aaatagctcc cttgattgtt caagaaaagt ccatcgctgc tcaaaacagc
    12481 tatattcata ttttagctga cagtctggcg tcctttgatt atacccagat tgagcagatt
    12541 gttaatgaga gtcgtcaggt gcaaaggcag aatcgcatgg aaggaatttc cagaccgacg
    12601 ccaatcacca tgccaatcac caagcagtta tcggctatta tgagggcaga agcccatcta
    12661 ctctatcgga tgatggaatc ccctcttgtt ttgaacgatt accgtttgcg agaagacttt
    12721 gcatttgcta cacctgaatt tcaggtctta tatgacttgc ttggccagta tggaaatctt
    12781 cctccagaag ttttagcaga gcagacagag gaagttgaaa gagcttggta ccaagtttta
    12841 gctcaggatt tgcctgctga gatatcgccg caggaactta gtgaagtaga gatgactcga
    12901 aacaaggctc tcttgaatca ggacaatatg agaatcaaaa agaaggtgca ggaagctagc
    12961 catgtaggag atacagatac agccctagaa gaattggaac gtttaatttc ccaaaagaga
    13021 agaatggagt aataatggca acaaaacaaa aagaagtaac aacatttgac gtacaggtag
    13081 cagaatttat ccgtaatcat aagcaaaaag ggacagcaac agatgatgaa atcaatgcaa
    13141 gtctggttat tccttttacc ttggacgctg atgggattga agatctcttg caacggattc
    13201 aggatgcagg aatttctatc acagataacg aaggaaatcc aagtgcgcgt gttcttagca
    13261 atgaagaaga accagaactc agcgatgagg acttgattgg gtcaacttct gctaaggtca
    13321 atgaccctgt ccgtatgtac ttgaaagaaa taggggtcgt tcctctcttg accaatgaag
    13381 aggagaaaga gttggcactg gctgttgaag ctggtgatat cgaagccaaa caacgtcttg
    13441 cggaagccaa tcttcgtttg gttgtttcca ttgccaaacg ctatgtcggt cgtggcatgc
    13501 agttccttga cttgattcaa gaaggaaata tgggcttgat gaaggcggtt gacaagtttg
    13561 actattctaa agggttcaag ttttcaactt atgcaacttg gtggattcgt caggctatca
    13621 ctcgtgctat tgcggaccaa gctcgtacca tccgtatccc agttcacatg gttgaaacta
    13681 tcaataaatt ggttcgtgaa cagcggaatc tccttcaaga attggggcaa gatccgacac
    13741 cagaacagat tgctgaacga atggatatga cacctgataa ggttcgtgaa atcttgaaga
    13801 ttgcccaaga accagtatct cttgaaactc ctatcggtga agaggacgat agccaccttg
    13861 gagactttat cgaagatgaa gtgattgaaa atccagtgga ttatacgact cgtatcgtct
    13921 tgcgtgagca attggatgaa atcttagata ctcttacaga ccgtgaagaa aatgttctgc
    13981 gtctacgttt tggactagat gatggaaaaa tgcgcacact tgaagatgtg gggaaagtct
    14041 ttaacgtaac tcgtgagcgt atccgtcaga ttgaagcaaa ggctttgaga aaactacgcc
    14101 aaccaagtcg tagcaaaccg cttcgtgatt ttattgaaga ctaagagtga ggaaaatatg
    14161 gcttatacag aagagcaaat tgaaaacatc aaaacacgga ttttaacagc cttggaagaa
    14221 gtcatcgacc ctgagttggg aatcgatatt gtcaatcttg gtttgatcta tgagattcgt
    14281 tttgacggtg acacagggca aacagagatt gacatgactt tgacaactat gggttgtccc
    14341 ttagcagacc ttttgacaga ccagatttat gatgctatga tagaggttcc agaagtaacg
    14401 gatactgagg ttaaattagt ctggtatcca gcctggacag ttgaaaaaat gagtcgctat
    14461 gcccgcattg ccctaggcat taagtaaaca tataaaagca tgtgagagac tgttggaaaa
    14521 gcgaggaaat ttcccctctt ttcctctagt ctctcctttc ttttgctgat tttattcaaa
    14581 gaaaatgata taatagtagt tatggagaaa aagaaattac gcatcaatat gttgagttca
    14641 agtgagaaag tagcaggaca gggagtttca ggtgcttacc gtgaattagt tcgtcttctt
    14701 caccgtgctg ccaaggacca attgattgtt acagaaaatc ttccaatcga ggcagatgtg
    14761 actcactttc atacgattga ttttccctat tatttatcaa ccttccaaaa gaaacgctca
    14821 gggagaaaga ttggctatgt gcatttcttg ccagctacac ttgagggaag tttgaaaatt
    14881 ccatttttct taaagggaat tgtgaaacgc tatgtatttt ctttttacaa ccggatggag
    14941 cacttggttg tggtcaatcc tatgtttatt gaggatttgg tagcagctgg tattccacgt
    15001 gaaaaagtga cctatattcc taactttgtc aacaaggaaa aatggcatcc tctaccacaa
    15061 gaagaggtag tcagactgcg cacagatctt ggtcttagtg acaatcagtt tatcgtagta
    15121 ggtgctgggc aagttcagaa acgtaaaggg attgatgact ttatccgtct ggctgaggaa
    15181 ttgcctcaga ttacctttat ctgggctggt ggcttctctt ttggtggtat gacagatggt
    15241 tatgaacact ataagaaaat tatggaaaat ccccctaaaa atttgatttt tccaggcatt
    15301 gtatcgccag agcggatgcg cgaattgtat gctctagcgg atcttttctt gttgcctagt
    15361 tacaatgagc tctttcctat gactatttta gaagctgcga gttgtgaggc tcctattatg
    15421 ttgcgtgatt tagatctcta taaggtgatt ttggagggaa attatcgggc gacagcgggt
    15481 agagaagaga tgaaagaggc tattttggaa tatcaagcaa atcctgctgc cttaaaagat
    15541 ctcaaagaaa aggctaagaa tatttccaga gagtattctg aagagcatct gttacaaatc
    15601 tggttggact tttatgagaa acaagccgct ttagggagaa agtaaaaagt gaggtaatct
    15661 atgcgaattg gtttatttac agatacctat tttcctcaag tttctggtgt tgcgaccagt
    15721 attcgaacct tgaaaacaga acttgaaaag cagggacatg ctgtttttat ctttacgacg
    15781 acagataagg atgtcaatcg ctacgaagat tggcaaatta tccgcattcc aagtgttcct
    15841 ttctttgctt ttaaggatcg tcgctttgcc taccgaggtt ttagcaaggc acttgaaatt
    15901 gctaaacagt atcagctaga tattatccat actcagacag aattttctct tggcctgttg
    15961 gggatttgga ttgcgcgtga attgaaaatt ccagtcatcc atacctatca cacccagtat
    16021 gaagactatg tccattatat tgctaagggg atgttgatcc ggccgagtat ggtcaagtat
    16081 ctggttagag gtttcctgca tgatgtggat ggggttattt gtcctagtga gattgtccgt
    16141 gacttgctat ctgattataa ggtcaaggtt gaaaaacggg tcattcctac tgggattgaa
    16201 ttagccaagt ttgagcgtcc ggaaatcaag caggaaaatt tgaaagaact gcgtagtaaa
    16261 ctagggattc aagatggtga aaagacgttg cttagtcttt cgagaatctc ctatgaaaaa
    16321 aatattcaag cagttttagc agcctttgct gatgttctga aagaggaaga caaggttaaa
    16381 ctggtagtag ctggggatgg cccttatctg aatgacctca aagagcaagc ccagaaccta
    16441 gagattcaag actcagtcat ctttacaggg atgattgctc ctagtgagac ggctctttac
    16501 tataaagcgg cggatttctt catttcggca tcgacaagcg aaacgcaagg tttgacctac
    16561 ttggaaagct tagccagtgg aacacctgtc attgctcacg gaaatcctta tttgaacaac
    16621 ctcatcagtg ataaaatgtt tggaaccttg tactatggag aacatgattt ggctggtgct
    16681 attttggaag ccctgattgc aacaccagac atgaacgagc ataccttatc agagaaattg
    16741 tatgagattt cagctgagaa ctttgggaaa cgagtgcatg agttttatct ggatgccatt
    16801 atttcaaata acttccagaa agatttggct aaagatgata cggtcagtca gcgtatcttt
    16861 aagacagttt tgtatcttcc gcaacaggtg gttgctgtac ctgtaaaagg atctagacgc
    16921 atgttgaagg cttcaaaaac acagttgatc agtatgagag actattggaa agaccatgaa
    16981 gaatagaaag aggaacagct atgaaaaaaa caattaatga gaagcggtcg tgataaaaag
    17041 attgcgggtg tttgtgctgg ggtggcccat tatctggata tggatccgac tatcgttcaa
    17101 gtcatttggg gtgttcttac ttgctgttac ggagctggaa ttgtagctta cattatttta
    17161 tggattatcg caccagtagc aactgactat tgaaaactag ctcaattcat gctaagataa
    17221 tagaaaatag aatgtaacga aggagagaaa aatggcattt ggagataatg gaaatcgtaa
    17281 aaaaactatg tttgagaaaa taaccttgtt tatcgtgatt atcatgctag tagcaagttt
    17341 attgggaatt tttgcaactg caattggtgc cctcagtaat ctataaaata gattcaagaa
    17401 aatttagtga ctgggatttc ccagcccttt tttaaagtga gaagaaataa tgagtatgtt
    17461 tttagataca gctaagatta aggtcaaggc tggtaatggt ggcgatggta tggttgcctt
    17521 tcgtcgtgaa aaatatgtcc ctaatggagg cccttggggt ggtgatggtg gtcgtggagg
    17581 caatgtggtc ttcgttgtag acgaaggact acgtaccttg atggatttcc gctacaatcg
    17641 tcatttcaag gctgattctg gtgaaaaagg gatgaccaaa gggatgcatg gtcgtggtgc
    17701 tgaggacctt agagttcgag taccacaagg tacgactgtt cgtgatgcgg agactggcaa
    17761 ggttttaaca gatttgattg aacatgggca agaatttatc gttgcccacg gtggtcgtgg
    17821 tggacgtgga aatattcgtt tcgcgacacc aaaaaatcct gcaccggaaa tctctgaaaa
    17881 tggagaacca ggtcaggaac gtgagttaca attggaacta aaaatcttgg cagatgtcgg
    17941 tttagtagga ttcccatctg tagggaagtc aacactttta agtgttatta cctcagctaa
    18001 gcctaaaatt ggtgcctacc actttaccac tattgtacca aatttaggta tggttcgcac
    18061 ccaatcaggt gaatcctttg cagtagccga cttgccaggt ttgattgaag gggctagtca
    18121 aggtgttggt ttgggaactc agtttctccg tcacatcgag cgtacacgtg ttatccttca
    18181 catcattgat atgtcagcta gcgaaggccg tgatccatat gaggattacc tagctatcaa
    18241 taaagagctg gagtcttaca atcttcgcct catggagcgt ccacagatta ttgtagctaa
    18301 taagatggac atgcctgaga gtcaggaaaa tcttgaagaa tttaagaaaa aattggctga
    18361 aaattatgat gaatttgaag agttaccagc tatcttccca atttctggat tgaccaagca
    18421 aggtctggca acacttttag atgctacagc tgaattgtta gacaagacac cagaattttt
    18481 gctctacgac gagtccgata tggaagaaga agcttactat ggatttgacg aagaagaaaa
    18541 agcctttgaa attagtcgtg atgacgatgc gacatgggta ctttctggtg aaaaactcat
    18601 gaaactcttt aatatgacca actttgatcg tgatgaatct gtcatgaaat ttgcccgtca
    18661 gcttcgtggt atgggggttg atgaagccct tcgtgcgcgt ggagctaaag atggggattt
    18721 ggtccgcatt ggtaaatttg agtttgaatt tgtagactag gagactggta tgggagataa
    18781 accgatatct ttccgagatg cggatggtaa ttttgtttcc gccgcagacg tttggaatga
    18841 aaagaaattg gaagaactat ttaatcgtct caatccaaat cgtgccttga gattggcacg
    18901 aactaaaaag gaaaatccat ctcagtaaag aagctaaaaa atcccggctc tttgtcaact
    18961 gtagtgggtt gaagtcagct aagctcgaga aaggacaaat tttgtccttt cttttttgat
    19021 attcagagcg ataaaaatcc gttttttgaa gttttcaaag tttcgaaaac caaaggcatt
    19081 gcgcttgata agtttgatga gattattggt cgcttccagt ttggcattag aatagtgtag
    19141 ttgaagggcg ttgataatct tttctttatc tttgaggaag gttttaaaga cagtctgaaa
    19201 aataggatga acctgcttaa gattgtcctc aataagtccg aaaaatttct ctggttcctt
    19261 attctggaag tgaaaaagca agagctgata gagttgatag tggtgtttca agtcttccga
    19321 atagctcaaa agcttgttta aaatctcttt attggttaag tgcatacgaa aaataggacg
    19381 ataaaatcgc ttatcactca gtttacagct atcctgttga atgagtttcc agtagcgctt
    19441 gatagccttg tattcatggg attttcgatg aaactgattc atgatttgga catgcacacg
    19501 actcatagca cggctaagat gttgtacaat gtgaaagcga tcaagaacga ttttagcaca
    19561 cgggaaaagt tgtctagcta agtcatagta aggactaaac atatccatag taatgatttt
    19621 gacgcgacat cggacggctc tatcatattt aagaaagtga tctcggatga cagcttgtgt
    19681 tctaccttca agaacagtga tgatatcgag cttttcaaaa tcttgcgcaa t
//
LOCUS       DAVLHB010000041        18626 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLHB010000041 DAVLHB010000000
VERSION     DAVLHB010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18626
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.041"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..445
                     /locus_tag="VXE36_001583"
     CDS             <1..445
                     /locus_tag="VXE36_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0779850.1"
                     /translation="VFCLEADNQEHLFDQVATLLEEREIVTPTYREALITREKSFPTG
                     LDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFII
                     NNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            483..788
                     /locus_tag="VXE36_001584"
     CDS             483..788
                     /locus_tag="VXE36_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0779851.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            836..2311
                     /locus_tag="VXE36_001585"
     CDS             836..2311
                     /locus_tag="VXE36_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0779852.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2616..9317
                     /locus_tag="VXE36_001586"
     CDS             2616..9317
                     /locus_tag="VXE36_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0779853.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVKVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVVAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTNAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEKKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9565..10421)
                     /locus_tag="VXE36_001587"
                     /pseudo
     CDS             complement(9565..10421)
                     /locus_tag="VXE36_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10633..10992)
                     /locus_tag="VXE36_001588"
     CDS             complement(10633..10992)
                     /locus_tag="VXE36_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0779854.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            11084..12040
                     /locus_tag="VXE36_001589"
                     /pseudo
     CDS             11084..12040
                     /locus_tag="VXE36_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            12024..12581
                     /locus_tag="VXE36_001590"
     CDS             12024..12581
                     /locus_tag="VXE36_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0779855.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPAADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12574..12828
                     /locus_tag="VXE36_001591"
     CDS             12574..12828
                     /locus_tag="VXE36_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779856.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAMGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12840..14894
                     /locus_tag="VXE36_001592"
     CDS             12840..14894
                     /locus_tag="VXE36_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0779857.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSFIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            15073..15933
                     /locus_tag="VXE36_001593"
     CDS             15073..15933
                     /locus_tag="VXE36_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0779858.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            16144..16854
                     /gene="ccdA2"
                     /locus_tag="VXE36_001594"
     CDS             16144..16854
                     /gene="ccdA2"
                     /locus_tag="VXE36_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0779859.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIIFLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16874..17440
                     /locus_tag="VXE36_001595"
     CDS             16874..17440
                     /locus_tag="VXE36_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0779860.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17451..18563
                     /gene="msrB"
                     /locus_tag="VXE36_001596"
     CDS             17451..18563
                     /gene="msrB"
                     /locus_tag="VXE36_001596"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0779861.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5624 a         3535 c         4080 g         5387 t
ORIGIN      
        1 tgtgttttgc ttagaagcgg ataatcaaga acatctcttt gatcaggttg caactttatt
       61 ggaagaacga gaaattgtaa ctccaactta tcgtgaagcc ttgatcacgc gtgaaaagtc
      121 atttccaact ggtttagata tggaatttct aggaaaggac ttgccaaatg tagcgattcc
      181 tcacacagat attgttcata atctagctga gaaagtggtg gttgttcgat tagaaaaacc
      241 agtaactttt cacaatatga tagctcctga taaggaagta gaagtatctc tactcttctt
      301 tatcattaac aattcaagtt caagtcaaac gaacattctg gctcagttga tggacttttt
      361 cacaggaaat ggtcatcttg aagacctatc aaaaatttct gaaccagaaa aactttatgc
      421 ttacattgct gaagcaaccg cttaatcttg tctattaaaa aataaaatcg gaggaaatcc
      481 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
      541 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      601 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      661 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      721 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacatggat
      781 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      841 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      901 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      961 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
     1021 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
     1081 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
     1141 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
     1201 cgatacactt gatgtcgata tctttgatat ctggcacttg tctatcacag gtctcttgat
     1261 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
     1321 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
     1381 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
     1441 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1501 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1561 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1621 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1681 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1741 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcgag gacgtaaatt
     1801 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1861 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1921 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1981 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     2041 aggtacactt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     2101 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     2161 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     2221 agtcttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     2281 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     2341 aaatcaaaga gcaaactagg aaactagccg caggttgcta aaaacacagt tttgaggttg
     2401 tagataagac tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg
     2461 aagtcagtaa tcatatctac ggcaaggcga cactgacgaa gtttgaattg gattttcgca
     2521 gagtgtaaat tgttgaaact aggttgtcat accatgtata ccacttgggc tttggtagta
     2581 gctaactgca ctaaatataa tataaggagg gttttatggg gaaaggccat tggaatcgga
     2641 aaagagttta tagcattcgt aagtttgctg tgggagcttg ctcagtaatg attgggactt
     2701 gtgcagttct attaggagga aatatagctg gagaatctgt agtttatgcg gatgaaacac
     2761 ttattactca tactgctgag aaacctaaag aggaaaaaat gatagtagaa gaaaaggctg
     2821 ataaagcttt ggaaactaaa aatgtagttg aaaggacaga acaaagtgaa cctagttcaa
     2881 ctgaggctat tgcatctgag aagaaagaag atgaagccgt aactccaaaa gaggaaaaag
     2941 tgtctgctaa accggaagaa aaagctccaa ggatagaatc acaagcttca agtcaagaaa
     3001 aaccgctcaa ggaagatgct aaagctgtaa caaatgaaga agtgaatcaa atgattgaag
     3061 acaggaaagt ggattttaat caaaattggt actttaaact caatgcaaat tctaaggaag
     3121 ccattaaacc tgatgcagac gtatctacgt ggaaaaaatt agatttaccg tatgactgga
     3181 gtatctttaa cgatttcgat catgaatctc ctgcacaaaa tgaaggtgga cagctcaacg
     3241 gtggggaagc ttggtatcgc aagactttca aactagatga aaaagacctc aagaaaaatg
     3301 ttcgccttac ttttgatggc gtctacatgg attctcaagt ttatgtcaat ggtcagttag
     3361 tggggcatta tccaaatggt tataaccagt tctcatatga tatcaccaaa taccttcaca
     3421 aagatggtcg tgagaatgtg attgctgtcc atgcagtcaa caaacagcca agtagccgtt
     3481 ggtattcagg aagtggtatc tatcgtgatg tgactttaca agtgacagat aaggtgcatg
     3541 ttgagaaaaa tgggacaact attttaacac caaaacttga agaacaacaa catggcaagg
     3601 ttgaaactca tgtgaccagc aaaatcgtca atacggacga caaagaccat gaacttgtag
     3661 ccgaatatca aatcgttgaa cgaggtggtc atgctgtaac aggcttagtt cgtacagcga
     3721 gtcgtacctt aaaagcacat gaatcaacaa gcctagatgc gattttagaa gttgaaagac
     3781 caaaactctg gaccgtttta aatgacaaac ctgccttgta cgaattgatt acgcgtgttt
     3841 accgtgacgg tcaattggtt gatgctaaga aggatttgtt tggttaccgt tactatcact
     3901 ggactccaaa tgaaggtttc tctttgaatg gtgaacgtat taaattccat ggagtatcct
     3961 tgcaccacga ccatggggcg cttggagcag aagaaaacta taaagcagaa tatcgccgtc
     4021 tcaaacaaat gaaggagatg ggagttaact ctatccgtac aacccacaac cctgctagtg
     4081 agcaaacctt gcaaatcgca gcagaactag gtttactcgt tcaggaagag gcctttgata
     4141 cgtggtatgg tggcaagaaa ccttatgact atggacgttt ctttgaaaaa gatgccactc
     4201 acccagaagc tcgaaaaggt gaaaaatggt ctgattttga cctacgtacc atggtcgaaa
     4261 gaggcaaaaa caaccctgct atcttcatgt ggtcaattgg taatgaaata ggtgaagcta
     4321 atggtgatgc ccactcttta gcaactgtta aacgtttggt caaggttatc aaggatgttg
     4381 ataagactcg ctatgttacc atgggagcag ataaattccg tttcggcaat ggtagcggag
     4441 ggcatgagaa aattgctgat gaactcgatg ctgttggatt taactattct gaagataatt
     4501 acaaagccct tagagctaag catccaaaat ggttgattta cggttcagaa acatcatcag
     4561 caacccgtac acgaggaagt tactatcgcc ctgaacgtga attgaaacat agcaatggac
     4621 ctgagcgtaa ttatgaacag tcagattatg gaaatgatcg tgtgggttgg gggaaaacag
     4681 caaccgcttc atggactttt gaccgtgaca acgctggcta tgctggacag tttatctgga
     4741 caggtacgga ctatattggt gaacctacac catggcacaa ccaaaatcaa actcctgtta
     4801 agagctctta ctttggtatc gtagatacag ccggcattcc aaaacatgac ttctatctct
     4861 accaaagcca atgggtttct gttaagaaga aaccgatggt acaccttctt cctcactgga
     4921 actgggaaaa caaagaatta gcatccaaag tagctgactc agaaggtaag attccagttc
     4981 gtgcttattc gaatgcttct agtgtagaat tgttcttgaa tggaaaatct cttggtctta
     5041 agactttcaa taaaaaacaa accagcgatg ggcggactta ccaagaaggt gcaaatgcta
     5101 atgaacttta tcttgaatgg aaagttgcct atcaaccagg taccttggaa gcaattgctc
     5161 gtgatgaatc tggcaaggaa attgctcgag ataagattac gactgctggt aagccagcgg
     5221 cagttcgtct tattaaggaa gaccatgcga ttgcagcaga tggaaaagac ttgacttaca
     5281 tctactatga aattgttgac agccagggga atgtggttcc aactgctaat aatctggttc
     5341 gcttccaatt gcatggccaa ggtcaactgg tcggtgtaga taacggagaa caagccagcc
     5401 gtgaacgcta taaggcgcaa gcagatggtt cttggattcg taaagcattt aatggtaaag
     5461 gtgttgccat tgtcaaatca actgaacaag cagggaaatt cacccttact gctcactctg
     5521 atctcttgaa atctagtcaa gtcactgtct ttactggtaa gaaagaagga caagaaaaga
     5581 ctgttttggg gacagaggtg ccaaaagtac agaccattat tggagaggca cctgaaatgc
     5641 ctaccactgt tccgtttcta tacagtgatg gtagtcgtgc agaacgtcct gtaacctggt
     5701 cttcagtaga tgtgagcaag cctggtattg taacggtgaa aggtatggct gacggacgag
     5761 aagtagaagc tcgtgtagaa gtgattgctc ttaaatcaga gctaccagtt gtgaaacgta
     5821 ttgctccaaa tactgacttg aattctgtag acaaatctgt ttcctatgtt ttgactgatg
     5881 gaagtgtaca agagtacgaa gtagatagct gggagattac ggaagtagat aaagccaaac
     5941 tttcagtagc tggatcacgt attcaaatga ctggtcagtt agctggagaa actattcatg
     6001 caacccttgt ggtagaagaa ggaaatgctg cagcacctgt agtgccaact gttactgttg
     6061 gaggtgaagc agtaacaggt cttactagtc gacaaccaat gcaatatcgt actctatctt
     6121 atggtgccca attgccagaa gtcacagcaa gtgctgaaaa tgctgatgtg acagttcttc
     6181 aagcaagcgc agcaaacggc atgcgtgcga gcatctttat tcagcctaaa gatggtggcc
     6241 ctcttcaaac ctatgcaatt caattccttg aagaagcgcc aaaaattgct cacttgagtt
     6301 tgcaagtgga aaaagctgac agtctcaaag aagaccaaac tgtcaaattg tcggttcgag
     6361 ctcactatca agatggaacg caagctgtat taccagctga taaagtaacc ttctctacaa
     6421 gtggtgaagg ggaagtcgca attcgtaaag gaatgcttga gttgcataag ccaggagcag
     6481 tcactctgaa cgctgaatat gagggagcta aaggccaagt tgaactcact atccaagcca
     6541 atactgagaa gaagattgcg caatccatcc gtcctgtaaa tgtagtgaca gatttgcatc
     6601 aggaaccaag tcttccagca acagtaaaag ttgagtatga caaaggtttc cctaaaactc
     6661 ataaagtcac ttggcaagct attccgaaag aaaaactaga ctcctatcaa acatttgaag
     6721 tactaggtaa agttgaagga attgaccttg aagcgcgtgc aaaagtctct gtagaaggta
     6781 tcgtttcagt tgaagaagtc agtgtgacaa ctccaatcgc agaagcacca caattaccag
     6841 aaagtgttcg gacatatgat tcaaatggtc acgtttcatc agctaaggtt gcatgggatg
     6901 cgattcgtcc agagcaatac gctaaggaag gtgtctttac agttaatggt cgcttagaag
     6961 gtacgcaatt aacaactaaa cttcatgttc gcgtatctgc tcaaactgag caaggtgcaa
     7021 acatttctga ccaatggacc ggttcagaat tgccacttgc ctttgcttca gactcaaatc
     7081 caagcgaccc agtttcaaat gttaatgaca agctcatttc ctacaataac caaccagcca
     7141 atcgttggac aaactggaat cgtactaatc cagaagcttc agtcggtgtc ctattcggag
     7201 attcaggtat tttgagcaaa cgttcagttg ataacttaag cgttggcttc catgaagacc
     7261 atggagttgg tgcaccgaag tcttatgtga ttgagtatta tgttggtaag actgtcccaa
     7321 cagctcctaa aaaccctagt tttgttggta atgaggacca tgtctttaat gattctgcca
     7381 actggaaacc agttactaat ctaaaagccc ctgctcaact caaggctgga gaaatgaacc
     7441 actttagctt tgataaagtt gaaacctatg ctgttcgtat tcgcatggtg agagcagaca
     7501 acaaactagg aacgtctatc acagaggtac aaatctttgc gaaacaagtt gcggcagcca
     7561 agcaaggaca aacaagaatc caagttgacg gtaaagactt agcaaacttc aaccctgatt
     7621 tgacagacta ctaccttgag tctgtagatg gaaaagttac ggcagtcaca gcaagtgtta
     7681 gcaacaatgg cctcgctacc gtcgttccaa gcgttcgtga aggtgagccg gttcgtgtca
     7741 tcgcgaaagc tgaaaatggc gacatcttag gagaataccg tctgcacttc actaaggata
     7801 agaacttact ttctcataaa ccagttgttg cggttaaaca agctcgcttg ctacaagtag
     7861 gtcaagcact tgaattgccg actaaggttc cagtttactt cacaggtaaa gacggctacg
     7921 aaacaaaaga tttgtcagtt gaatgggaag aagttccagc agaaaatctg acaaaagcag
     7981 gtcaatttac cgttcgaggc catgtccttg gtagtgatct tgttgctgag gtcactgtac
     8041 gagtgacaga caaactaggc gaagctcttt cagataaccc taactatgat gaaaacagta
     8101 accaggcctt tgcttcagca accaatgata ttgacaaaaa ctctcatgac cgcgttgact
     8161 atctcaatga cggagatcat tcagaaaatc gtcgttggac aaactggtct ccaacaccat
     8221 cttctaatcc agaagtatca gcgggtgtga tcttccgtga aaatggtaag attgtagaac
     8281 ggactgttgc tcaagccaaa cttcacttct ttgcagatag tggtacgaat gcaccaacta
     8341 aactcgtttt agaacgctat gtcggtccag agtttgaagt gccaacctac tattcaaact
     8401 accaagccta cgacgcagac catccattca acaatccaga aaattgggaa gctgtgcctt
     8461 atcgtgcgga taaagacatc gcagctggtg atgaaatcaa cgtaacattt aaagctgtca
     8521 aagccaaagc tatgagatgg cgtatggagc gtaaagcaga taagagcggt gttgcgatga
     8581 ttgagatgac cttccttgca ccaagtgaat tgcctcaaga aagcacgcaa tcgaagattc
     8641 ttgtagatgg aaaagaactt gctgatttcg ctgaaaatcg tcaagactat caaattacct
     8701 ataaaggtca acggccaaaa gtctcagttg aagaaaacaa tcaagtagct tcaactgtgg
     8761 tagatagtgg agaagatagc cttccagtac ttgttcgcct cgtttcagaa agtggaaaac
     8821 aagtcaagga ataccgtatc cacttgacta aggaaaaacc agtttctgag aagacagttg
     8881 ctgctgtaca agaagatctt ccaaaactcg aatttgttga aaaagatttg gcctacaaga
     8941 cagttgagaa aaaagattca acactgtatc taggtgaaac tcgtgtagaa caagaaggaa
     9001 aaactggtaa agaacgtatc tttacagcga ttaatcctga tggaagtaag gaaaaaaaac
     9061 tccgtgaagt ggtagaagct ccgacagacc gcatcgtctt ggttggaacc aaaccagtag
     9121 ctcaagaagc taaaaaacca caagtgtcag aaaaagcaga tacaaaacca attgattcaa
     9181 gtgaagctag tcaaactaat aaagcccagt taccaaatac aggtagtgcg gcaagccaag
     9241 cagcagtagc agcaggttta gctcttctag gtttgagtgc aggattagta gttactaaag
     9301 gtaaaaaaga agactagaaa ttttgatacc ttctttatca ttaaagacca aagaaaaact
     9361 cttgtcctaa atagaagata aagagtctgg aacaaaatag ttctcaacca caaaaaagct
     9421 agatatttcc aattgcggaa ctctagcttt ttaattttga gtcgttctct tattgtatag
     9481 tagattgaaa ctagaatagt acacttctac ttctaaaaca ttgttagaaa tcaatttgac
     9541 tgtccttatc gatttgtcct gttcttattt catttcacta tgttttagga ggttattggc
     9601 cataagtacc aatcccatgt caattctcac ttgacgcttc cctctcagat tacatctctt
     9661 gtaacccaaa caagccttta tctgcccaaa gacaggttcc acatcaatct tgcgttgagc
     9721 gaaaatctgt ctaccttggg gagataaaag cgcctgacat tctttagctt tcaagttttg
     9781 atagcgttcg ttcatataca gtcccttttg agggactgat tcaggttcat cagcgtagta
     9841 aaccttgatt tcctgttgaa agtctgtctg tgttttctgg tacttgatat ggtgaaaacg
     9901 atagcaccag ccatcaggat gtgtgtagct atcctccttg tcattatagt gccaattcgc
     9961 taagttttta gctgactgtt tataccctct cttttgtttc ttatcaaaca tggcatattt
    10021 aatcagaagg ggagtgattt cttcttgaaa atagacctgt atctgttctt gaagtttggc
    10081 ggagaatttc tctgtcgttt tcttccacac aaaactatac ttgttggcat tggcttcaat
    10141 cttagttccg tcaataaaca aacaatctaa ggtcactaac tcttccattt ttcaattttt
    10201 cgaccagaga aaatcccttg tgaataggca aatagaagag tagatacaag cattttaggg
    10261 tgataagacg ggcgatcaaa ggcatgatag gaggtgtaga agtgacgttc ctccaaggta
    10321 ttcaccactt tttcaatagt aaagacgaga tggtcttgtg gtaagaagga actgatttct
    10381 agtggtaaag ttgtttgatt tgtgttatag tgaatatgca tgggatagcc tttttaaatg
    10441 gtttattaag caattctatt ttaccaagac tatcgtaacc atgcaaaaaa agcaacggca
    10501 aatccgttgc tttttttgga gataagagac tattgtccca gactcttttc tttgtataaa
    10561 attgtatagt gttattgtct atactatttt ttagagaaag caaaaatccc tagaaaatgc
    10621 ttagggattc gactatttca ttaagaacaa ttcaacaatc atttctatat acatgataag
    10681 ggttaataag aatcctgcac gccagaagaa tttgataaat ttaggatagt aaaagctgcg
    10741 ttttttcaaa aggaagaaaa agacgagaat aatggctagg atcgagaggg ctagccccag
    10801 tctagggagg aaattatggg taaaggtttt agctgtaatc aagtaatact caaataccaa
    10861 gactggaaaa gccaaatccg caaagtttcg tcctagtttt tttaatctaa aaagtttggt
    10921 taggataatg cagacgacta aggtcagtat caataataaa atagatgcta atttcattaa
    10981 aatcataccc atattgtatc ataaaaaaag gctaatggaa acgagaaaca gaggaattta
    11041 taggaaagtc aggcttttga gattgtgggt gatttttgtt ataatgaaag tcatgaaatc
    11101 ttataatacc ttgaatgatt attatcgaaa actctttgga gaaaagactt ttaaagtccc
    11161 tattgatgcg ggatttgact gtcccaatcg tgatggaact gtggctcatg gaggctgtac
    11221 tttttgtacg gtttcaggtt ctggagatgc tattgtagcc ccagatgcgc ctatccgtga
    11281 gcaattttat aaggaaattg actttatgca ccgtaagtgg ccggatgttc agaagtatct
    11341 ggtttatttt caaaatttta ccaacaccca tgaaaaggtg gaagttattc gagagcgtta
    11401 tgaacaggct atcaatgagc caggtgtggt aggtaccaat attggaacgc gcccagactg
    11461 tttaccagac gaaaccatcg aatatttggc tgagttatcg gagtgcatgc atgtgacggt
    11521 tgaattgggc ttgcagacca cttatgaagc aacctctgac ctgattaacc gtgtgcattc
    11581 ttatgaattg taggtggaaa cggtcaagcg tttgagaaag tatcccaaga ttgagattgt
    11641 ttcccatttg atcaatggct tgcctggtga aacccatgag atgatggttg aaaatgtccg
    11701 ccgttgtgtc acggataacg atattcaagg gattaaactg catttgctcc atcttatgac
    11761 aaatactcgt atgcaacgag attaccatga gggacgttta caattgatga gtcaggacga
    11821 atatgtcagg gtcatctgtg accaactgga aattattccc aaacatatcg tcatccatcg
    11881 aattacagga gatgcgccta gggatatgct gattggtcct atgtggagcc tcaaaaaatg
    11941 ggaagtcctc aacagcattg agatggagat gcgacgtcgt ggaagtgttc aaggatgcaa
    12001 ggctgtaaaa caggagtttg aaaatgaaaa gaccacttga gatggcacat gattttttgg
    12061 ctgaggtcgt gacaaaagag gatgtcgtag tggatgcgac tatgggaaat ggtcatgaca
    12121 cgcttttttt agccaagcta gccaagcaag tctatgcctt tgatattcag aagcaagcct
    12181 tggaaaagac ccaagagcgt ttgcatcagg ctggcttgac aaatgcccag ttaatcttgc
    12241 aaggccatga gacactggac cagtttgtga taaaagctaa ggcagggatt tttaatctgg
    12301 gctatttgcc ggcagctgat aagtctgtca tcacccgacc gcagacaacg attgaggcat
    12361 tagaaaagct atgtggctta cttgtcaaag gtggacgaat tgctattatg atttactatg
    12421 gtcatgaagg aggcgatctc gagagagatg ctgtcttgga ttttgtgatc cagttgaacc
    12481 aacaagagta cacagctgcc atttaccgaa ctttaaacca agtcaacaac ccgccgtttt
    12541 tagtgatgat tgaaaaatta gagagataca gacatggata aacaatactt acacgaaaag
    12601 ctggatgcca tgcgccagaa ttttgttgaa tcaacccacc acgaacgagc gatgggcgtg
    12661 ctagaccaag cgcatatgag caaaaaaatg cttaaaatca agaaaaaatt agttgctctt
    12721 gaaatggaac ggtgccagag aaaaattgag cacaaagact gttccaagat tgaccaaaaa
    12781 atcaaagagc agaaggagat atttgaatcc tgttgtaaaa aagattaagg aggacgtgcg
    12841 tggaattact gatttacctc atcctatttt tactggtttt gattgtctca agtacaacca
    12901 ataagctcct gccctttttg cctctccctt tggtgcaaat tcttttggga attgtgattg
    12961 gtctcttttt acccaatact gactttcacc ttaatacgga gttgtttttg gcactggtta
    13021 tcggaccctt gcttttccga gaggctgaag aagcagatgt tacggctatt ttaaaacact
    13081 ggcgaatcat tgtttatctc atatttccag tgatttttat ctcgaccctg agtttgggtg
    13141 gcttggccca tcttctttgg ttcagccttc ccttggcagc ttgcttggct gttggggcag
    13201 cccttggtcc tacggacttg gtggcctttg cctctctttc ggagcgtttt agctttccta
    13261 agcgcgtgtc caatattctt aagggcgaag gactcttgaa tgatgcttct ggtttggtgg
    13321 cttttcaggt agctttgaca gcttggacaa ctggagcttt ttctctgggg caagctagca
    13381 gttcgctcat cttttcaatc ctaggcggtt ttttaattgg atttttaaca gccatgacca
    13441 accgcttcct ccataccttc ttgctaagtg tgcgcgcaac ggatattgcc agtgaacttt
    13501 tattagaatt gagtttgcct ctagtgacct tctttctggc agaagaagtt catgtttcag
    13561 gtattattgc cgtcgtagtt gctggaattt taaaggcaag tcgcttcaag aaaatcacgc
    13621 tcctcgaagc ccaagtggat acggtgaccg agacggtctg gcatacagtg acctttatgc
    13681 tcaacggttc tgtctttgtg attttaggga tggagttgga aatgatagca gaacctatct
    13741 tgaccaatcc aatctataat cctctacttt tattgctatc ttttatcgcc cttacctttg
    13801 tcctttttgt cattcgtttt attatgatct atggctatta tgcctataga acccgacgcc
    13861 tcaagaaaaa gctaaataag tatatgaagg acatgtttct cttgaccttt tcaggtgtta
    13921 agggaacggt gtcgattgct acgattctct tgataccaag taatctagaa caggagtatc
    13981 ctcttttgct tttccttgtt gcaggtgtga cgcttgttag ctttttaaca ggtctcttgg
    14041 tcttgcctca tctttctgat gaagaggaag aaagcaagga ttatcttatg catatcgcca
    14101 ttttgaatga agtaacgcta gagttggaaa aagagttgga agacaccaga aataaacttc
    14161 ccctctatgc ggctattgac aattatcatg gacgtattga aaatctcatt ttaagccaag
    14221 aaaaccagga tgatcaagaa gactgggctg ctttgaaact cttgattctt agtattgaaa
    14281 gtgatggttt ggaacaggcc tatgaagagg ggaacattag caatcgtgct taccgagttt
    14341 accaacgtta tctgaaaaat atagaacaag gaatcaatcg taaacttgcc tcaagactga
    14401 cctattattt tcttgtttcc ttgaggattt tacgttttct ccttcatgaa gtttttactc
    14461 ttggaaagac cttccgtagc tggaaggaca aggagcaaag ccgtctccgt gctcttgatt
    14521 atgaccaaat tgcagagctc tatcttgcca atacagagat gattattgaa agtttggaaa
    14581 acctgaaggg agtctacaga cgctctttga ttagttttat gcaggagtct cgtcttcgag
    14641 aaacaactat tatcagcagt ggtgcctttg tcgaacgggt tatcaatcgt gtcaaaccca
    14701 acaatatcaa tgaaatgctg agaggctatt atctggagcg caagttgatt ttcgaatacg
    14761 aagaaaaacg attaattaca actaagtatg ccaagaaatt acgacaaaat gtaaataact
    14821 tagagaacta ttccttgaag gaagctgcca ataccctgcc gtatgatatg gtggaattgg
    14881 taagaagaaa ttagttaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta
    14941 ccgtatgtat gtgactgact tcgtcagtct tatctacaac ctcaaaacag tgttttgagc
    15001 agcttgcggc tagctttcta gtttgctctt tgattttcat tgagtataag attataaatg
    15061 aaggagtatg acatgaaaaa gtggtggaaa gagctgatag acaagccttt attaaaagct
    15121 tttttgcatt attatcaagc atcagatagt gagttgacca gtgtcgcagt agcctactat
    15181 tggttgattt cgattttccc cctgcttttg gtggtggtca atatcctccc ctattttcag
    15241 attcctgtgg gagaatttct gggctttatg aaagacgtcc tgcccccaag cctctatgaa
    15301 ggtgtggaaa aaatagccag agaagtcttg acgcaacctt caacaggttt attgagtttt
    15361 tctgttttat cggcgttatg gagtttttca aaatctatga atttcttgca aaaagctttt
    15421 aacaaggctt atggcgtcga aaagagtcgt ggacttattt cccatcagat gctaagtctc
    15481 ctagtcagtt ttggcttgca gctcctcttt gcgtttgcct tgtttttgat cttatttggt
    15541 cagatgattt tggctttact tgctcattat tggacaaaag atggcattat ctatcaggct
    15601 ttacaagggt tggcaggtcc tctgatttat gccctcctct ttgctatctt ggtcatgctt
    15661 tattattttc ttcccaatct atctaacagg aaaattagct ataccctacc aggcagtgcc
    15721 tttgttctct tggtgatttt aggtgtacta actctgttct ctagttatct caattactat
    15781 gtccatcatt tggtggatgt ccgaatttta ggttccgttc ttcttgttgt tatgatgttt
    15841 tggtttatct tgattgctaa aattgttatc ctaggcgcgg ttatcaatgc cagtatgcag
    15901 agtttgaaag atccggtctt taaaaaagac taactattta tccattataa aagcgcatag
    15961 tatcaagact ttatagaacc ttgatactat gcgcttttgt gctttgacag ttttttgtat
    16021 agtttttgtc caagatttct aaatcatctg attaaattcc tattttcccc tatcattgtc
    16081 cctgtttttt cgaaaatgga aggagtataa taaatctatc aataaaatga taggaggaac
    16141 tttatgggtc atattttctt ttttctaagt gtctttttgg cagggattct atccttcttt
    16201 tctccttgta tcttaccttt gttaccggtc tatacaggag tgttactaga tgataaggat
    16261 ggtgctcagg cttctagcgg caaattttca atctcagtta ctagtttatt acgaactctg
    16321 gcctttatag caggaatttc ctttatattt attttgttgg gctatggagc tggtttttta
    16381 ggcgatttgc tttatgcttc ttggttccaa tatcttactg gggcaattat tatctttctt
    16441 ggtttgcacc aaatggagat tctacacttt aaggggcttt ataaagaaaa gaggctacaa
    16501 ctgcaaggac aggggcaaaa tggtaagggc tatagtcagg catttttatt gggcttgacc
    16561 tttagttttg cttggacgcc ttgcgtgggg ccggttctgg ggtctgtttt ggccttggcg
    16621 gcttcaggtg gttcaggagc ttggcaggga gctggtctca tgttggtgta tacgctgggc
    16681 ttggcgctac cattcttgct tctagctctg acctctagtt atgttttgaa acatttccga
    16741 aaacttcatc cctatctcgg aatcctcaaa aaagtgggtg gttttctcat tattgtgatg
    16801 ggactcttgg ttctgtttgg aaatgcttca attttaagtc aattatttga ataaaatgga
    16861 aaggaatatc aatatgaaaa aatggcaaac atgtgttctt ggagcaggtt cgctcctttg
    16921 tttgacggct tgttcaggca agtccgtgac tagtgaacac caaacgaaag atgaaatgaa
    16981 gacggagcag acagctagta aaacaagcgc agctaaaggg aaagaggtgg ctgattttga
    17041 attgatggga gtagatggca agacctaccg tttatctgat tacaagggca agaaagtcta
    17101 tctcaaattc tgggcttctt ggtgttccat ctgtctggct agtcttccag atacggatga
    17161 gattgctaaa gaagctggtg atgactatgt ggtcttgaca gtagtgtcac caggacataa
    17221 gggagagcaa tctgaagcgg actttaagaa ttggtataag ggattggatt ataaaaatct
    17281 cccagtccta gttgacccat caggcaaact tttggaaact tatggtgtcc gttcttaccc
    17341 aacccaagcc tttatagaca aagaaggcaa gctggtcaaa acacatccag gattcatgga
    17401 aaaagatgca attttgcaaa ctttgaagga attagcctag gaggtgtctt atgaatgata
    17461 agttaaaaat cttcttgttg ctaggagtat tttttctagc cataaccggt ttctatgttc
    17521 tattgatacg aaatgcaggg cagacagatg cctcgcaaat tgaaaaggcg gcagttagcc
    17581 aaggaggaaa agcagtgaaa aaaacagaaa ttagtaaaga cgcagacttg cacgaaattt
    17641 atctagctgg aggttgtttc tggggagtgg aggaatattt ctcacgcgtt cccggggtga
    17701 cggatgccgt ttcaggctat gcaaatggta gaggagaaac aaccaagtac gaattgatta
    17761 accaaacagg tcatgcagaa accgtccatg tcacctatga tgccaagcaa atttctctca
    17821 aggaaatcct gcttcactat ttccgcatta tcaatccaac cagcaaaaat aaacaaggaa
    17881 atgatgtggg gacccagtac cgtactggtg tttattacac agatgacaag gatttggaag
    17941 tgattaacca agtctttgat gaggtggcta agaaatacga tcaacctcta gcagttgaaa
    18001 aggaaaactt gaagaatttt gtggtggctg aggattacca tcaagactat ctcaagaaaa
    18061 atccaaatgg ctactgccat atcaatgtta atcaggcggc ctatcctgtc attgatgcca
    18121 gcaaatatcc aaaaccaagt gatgaggaat tgaaaaagac cctgtcacct gaggagtatg
    18181 cagttaccca ggaaaatcaa acagaacgag ctttctcaaa ccgttactgg gataaatttg
    18241 aatccggtat ctatgtggat atagcaactg gggaacctct cttttcatca aaagacaaat
    18301 ttgagtctgg ttgtggctgg cctagtttta cccaacccat cagtccagat gttgtcacct
    18361 acaaggaaga taagtcctac aatatgacgc gtatggaagt gcggagccga gtaggagatt
    18421 ctcaccttgg gcatgtcttt acggatggtc cacaggacaa gggcggctta cgttactgta
    18481 tcaatagcct ctctatccgc tttattccca aagaccaaat ggaagaaaaa ggctacgctt
    18541 atttactaga ttatgttgat taatactctt cgaaagtctc ttcaaaccac gtcagcgtcg
    18601 ccttaccgta tgtagggtta ctgact
//
LOCUS       DAVLHB010000042        18209 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLHB010000042 DAVLHB010000000
VERSION     DAVLHB010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.042"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            391..1437
                     /gene="pheS"
                     /locus_tag="VXE36_001597"
     CDS             391..1437
                     /gene="pheS"
                     /locus_tag="VXE36_001597"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0779862.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1437..1946
                     /locus_tag="VXE36_001598"
     CDS             1437..1946
                     /locus_tag="VXE36_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779863.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            2023..4428
                     /locus_tag="VXE36_001599"
     CDS             2023..4428
                     /locus_tag="VXE36_001599"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0779864.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKTIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYIATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4496..5497)
                     /locus_tag="VXE36_001600"
     CDS             complement(4496..5497)
                     /locus_tag="VXE36_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0779865.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPINSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5653..6056
                     /locus_tag="VXE36_001601"
                     /pseudo
     CDS             5653..6056
                     /locus_tag="VXE36_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6182..6448
                     /locus_tag="VXE36_001602"
     CDS             6182..6448
                     /locus_tag="VXE36_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0779866.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6709..8958
                     /gene="metE"
                     /locus_tag="VXE36_001603"
     CDS             6709..8958
                     /gene="metE"
                     /locus_tag="VXE36_001603"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0779867.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLTVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEVAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9022..9888
                     /gene="metF"
                     /locus_tag="VXE36_001604"
     CDS             9022..9888
                     /gene="metF"
                     /locus_tag="VXE36_001604"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0779868.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10573..12786
                     /gene="pnp"
                     /locus_tag="VXE36_001605"
     CDS             10573..12786
                     /gene="pnp"
                     /locus_tag="VXE36_001605"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0779869.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            12802..13419
                     /gene="cysE"
                     /locus_tag="VXE36_001606"
     CDS             12802..13419
                     /gene="cysE"
                     /locus_tag="VXE36_001606"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0779870.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13431..14315
                     /locus_tag="VXE36_001607"
     CDS             13431..14315
                     /locus_tag="VXE36_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0779871.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14397..15740
                     /locus_tag="VXE36_001608"
     CDS             14397..15740
                     /locus_tag="VXE36_001608"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0779872.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15733..16119
                     /locus_tag="VXE36_001609"
     CDS             15733..16119
                     /locus_tag="VXE36_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0779873.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16123..17007
                     /locus_tag="VXE36_001610"
     CDS             16123..17007
                     /locus_tag="VXE36_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0779874.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17144..17599
                     /locus_tag="VXE36_001611"
     CDS             17144..17599
                     /locus_tag="VXE36_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779875.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            17596..17742
                     /locus_tag="VXE36_001612"
     CDS             17596..17742
                     /locus_tag="VXE36_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779876.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            17885..18055
                     /locus_tag="VXE36_001613"
                     /pseudo
     CDS             17885..18055
                     /locus_tag="VXE36_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5491 a         3507 c         4101 g         5110 t
ORIGIN      
        1 tacgaaacaa ttgctaaaac atttatagaa attaatttta ctttcccaat cgatttgttt
       61 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
      121 taggtcttgc aagaatggta aaaatctgat aaactaagtg gtaattgaat agaaatctga
      181 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      241 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      301 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      361 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      421 cttcgcgaag aaacgctgac tagcttgaag cagattactg ctggaaatga aaaagagatg
      481 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      541 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      601 gatgtcttga ctgctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      661 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      721 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      781 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      841 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      901 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      961 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
     1021 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1081 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1141 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1201 tgcttcaagt gtggtggaga aggctgtaat gtatgtaaga aaacaggttg gatcgaaatt
     1261 atgggggccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1321 tactctggct ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1381 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1441 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caaacctttc
     1501 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaagctt
     1561 atagtctaaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1621 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1681 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaaggat
     1741 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1801 cttgggcttg gttaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1861 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1921 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1981 aaaagaacta gagtgacaac tgtcattctg gagaactaaa ttatgcttgt atcttataaa
     2041 tggttaaaag aattggtgga cattgatgtg ccatcacagg agttggctga aaaaatgtca
     2101 accacaggga tcgaggtaga gagtgtcgaa tcaccagctg ctgatctctc aaaaattgtt
     2161 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2221 aacgttggcg aagaagaaga gcgtcagatc gtttgtggtg ccccaaatgt gcgtgctggg
     2281 atcaaggtca tggtggctct tccaggagct cgtatcgctg acaattacaa aatcaaaaaa
     2341 ggaaaaatcc gtggcttaga gtcacttgga atgatctgtt cacttggtga attgggtatt
     2401 tctgactcag ttgtacctaa ggaattcgca gatggtattc aaattttgcc agaaaatgcc
     2461 gttccaggtg aggaagtctt ctcatatcta gacttggatg atgaaatcat cgaactttcc
     2521 atcacaccaa accgtgcaga tgccctttct atgtgtggag tggctcacga agtggcagcc
     2581 atctatgaca aggcagtcaa ctttaaagaa tttactctaa cagaaactaa tgaagctgcg
     2641 gcagatgccc tttctgtcag cattgagaca gacaaggcgc cttactatgc agctcgtatc
     2701 ttggacaatg tgaccatcgc accaagtcca caatggttgc aaaaccttct catgaacgaa
     2761 ggcatccgtc ccatcaataa cgtagtggac gtgacaaact acatcctgct ctattttggt
     2821 caaccaatgc atgcctttga cttggacaca tttgaaggga ctgacatccg tgtgcgtgaa
     2881 gcgcgtgctg gtgaaaaatt ggtgaccttg gacggtgaag aacgtgactt ggacgtgaat
     2941 gacctagtca tcactgttgc agacaagcca gtagcccttg caggtgtcat gggtggtcaa
     3001 gcaacagaaa tctctgaaaa atctagtcgt gttgtccttg aagctgctgt tttcaatggc
     3061 aaaactatcc gtaagacaag tggtcgcctg aaccttcgtt ctgagtcatc ttctcgcttt
     3121 gaaaaaggaa ttaatgtggc aacagttaat gaagcccttg atgcggcagc tagcctgatt
     3181 gcggaacttg caggtgcgac ggtgcgtaag ggtatcgttt cagcgggtga gcttgatact
     3241 tcagatgtag aagtttcttc aacccttgct gatgttaacc gtgtcctcgg aactgagctg
     3301 tcttatgctg atgtcgaaga cgtcttccgt cgtcttggct ttggtctttc tggaaatgca
     3361 gacagcttta cagtcagagt cccacgtcgt cgttgggata tcacaatcga agctgacctc
     3421 tttgaagaaa ttgctcgtat ctatggttat gaccgcttgc caactagtct accaaaagac
     3481 gatggtacag caggtgaatt gacagccaca caaaaactcc gccgtcaagt tcgtactatt
     3541 gctgaaggag caggtttgac agaaatcatc acctatgctc taacaactcc tgaaaaagca
     3601 gttgagttca cagctcaacc gagtaacctt actgaactca tgtggccaat gactgtggat
     3661 cgttcagtcc tccgtcaaaa tatgatttca gggatccttg ataccgttgc ctacaacgtg
     3721 gctcgtaaga ataaaaactt ggccctttat gagattggaa aagtctttga acaaacaggt
     3781 aatccaaaag aagaacttcc aaatgagatc aacagctttg cctttgcctt gacaggcttg
     3841 gttgctgaaa aagatttcca aacagcagca gttccagttg atttcttcta tgctaaggga
     3901 atccttgaag ccctatttac tcgtttgggc ctccaagtaa cctatatagc aacatctgaa
     3961 atcgctagcc ttcatccagg tcgtacagcc gtgatttcac tcggtgacca agttcttggt
     4021 ttccttggcc aagtgcatcc agtcactgcc aaggcttacg atattccaga aacgtatgta
     4081 gctgagctta acctttcagc catcgaaggg gcgctccaac ctgctgttcc atttgtggaa
     4141 atcaccaaat tcccagcagt cagccgtgac gttgcccttc tcctcaaggc agaagtgact
     4201 caccaagaag ttgtagatgc tatccaagct gccggcgtga aacgtttgac agatatcaaa
     4261 ctctttgacg tcttctcagg tgaaaaactg ggacttggta tgaagtcaat ggcttatagc
     4321 ttgaccttcc aaaatccaga agacagctta acggacgaag aagtcgcacg ctacatggaa
     4381 aaaatccaag cgtctctcga agaaaaagtc aatgcagaag tgcgttaaac gatagtagga
     4441 tacaaattcc ccctctagtt tatgaacact agaggggtga ttttatataa aataattaaa
     4501 atgtgatttc tgtaaaaata catctatgat cagagttttg aaaacttaca atgtctaaat
     4561 ctttaacata gtagtggttt ttaggcaata aaatatgatc tattgttgca ttaaaaagtt
     4621 ttggactttg gctattccaa gttcctcttt caaaaggtgg cagtacattt aatgcgtccc
     4681 tatgagagct tatttttgca agtgctccat gacgcatagt tgcattaaaa tcacctgcaa
     4741 taatagcctt tggatatttt gaagccaatt gattatgaat gatgtttaag tcttgcttcc
     4801 agatttccat taaacctggc agaggaggag cagtatgcaa ggcaatgata tctggtatat
     4861 tttgttttct cgaatgtaat acaattgtcc cgaaccgtgt tgtatgaaaa gttttagctt
     4921 ctgtatagaa accataactt ttcttgacaa tcacagtcac aggagctatt ccactattga
     4981 taggtggaga agtgaaaata tcatagttgg ccatagaaag tccaacttga tgaaacaata
     5041 gtttgattct ctggttttct tgctcacctc tgatattggt agctagttca gggaatatag
     5101 ccatatcggc gtcaaaatgg ctaaaaattc gctcaatatg ttgtgcttct atttgattag
     5161 cgacgttcca agttactaat tttaaggttt tagtcttatt tgatgcagaa gaaagggttt
     5221 tatctgttcc gaataatagt aatatgagcg atagtaagag caaaatgcca gagtaaaacc
     5281 gtatttgttt atttttcttg taaaaagata ggaaaaaaaa tacgaaactt aaaatagcag
     5341 ccatagttgc agtagctaag gggaaggcat aaatctgtgc caagataggt tgggtagata
     5401 gccaaatgtt aagattagaa gatgggaaaa aagaataagt tatgataggg atagaaaaga
     5461 gaatgaccga aagggcagag agaaatgttt taatcattgt gtgagtacct caatttgcaa
     5521 tggttgctcg gagctaatgt gactttgtga ctttacttga ttgatattct ttttcttgtc
     5581 ttcctcatag attaagtaca acccaagtaa aaaaagtcca atttaagatt gaaatgatta
     5641 aaaggcacag aaatgcaaga caattatact acaaaaggca aacatttgac aatcgatagc
     5701 cgtcgcttaa tcgaacgatg gaaaaaagaa ggaaaatcaa atagagaaat tgcctctcta
     5761 cttggaaaag ctcctcaaac tatccacact gaaatcaagc gtgggacagt ccgacaatgt
     5821 cttggaaaag ggcgcttcaa agagatttat tctgccgact acgctcaaca gtcttaagaa
     5881 actaaaggaa aagattctcc actatacata accaaaaatt ttcgcctgaa atgatggtga
     5941 tagctaaagg ggttaacgtg ggaatttcaa ccatttacta ttggattcat cgtggaaaat
     6001 tggggttaag caagcaggat ctgctttatc ctagaaaagg aaaatcgctt aagaaatagg
     6061 ctagcaccaa ctttaaaccc actggtcaat ctatcgaatc ataattcgct cattttttta
     6121 aaaatacata gacgtaaaaa aaagagggtt aagtgatgaa gaatagtgct attgggagta
     6181 attggaagga tgtccatctg agctctttag caaggaggaa atccttgaaa gtgatatgcg
     6241 agtggctatc atgagcgagt tgattgaggc taggtatgaa caaggaatca gtcagaaaaa
     6301 gctggaagaa gtcagtggaa taagccagcc tgtcatagct aggatggaga caggaaagac
     6361 tagtcctcag ttggatacag tcttaaaagt cctagccagt ttaggaaaga cactagcaat
     6421 cgtcccactt gaacagggaa aaagttgact agaatcagtt atagtctttt ctaataacag
     6481 gtcatagtca cttataagaa ttactaataa catgttttag tattctaatt ggaatatagc
     6541 tgtaaagtaa gaattacaaa ggatttgaga cgtttgcttc aagtcttttt cttttgtccg
     6601 aaacagatat atagtttcaa actatatcaa accctaattt tttacaatta tacagacgct
     6661 ttcttttctg ttaagatagt ttcaacaaca aattttggag gacacatcat gtcaactaca
     6721 atcatcggtt tccctcgttt gggcgaattc cgtgaattaa aatttacaac tgaaaaatac
     6781 tttagaaaag aaatctcaga agaagaactt ttagcagcag caaaagactt gcgtgctaaa
     6841 cactggaaca ttgtcaaaga aaaaggcatc actgaaattc catcaaatga cttttctcac
     6901 tatgataact tcctagatgc ggctttcctt ttcaacgtgg tgcctgcatc cgttcaaaac
     6961 ttggacttgt ctgaccttga gcgctacttc gctttgggac gtggttacca gggagaaaaa
     7021 ggggacgttc gcgcccttcc aatgaagaaa tggttcaaca ctaactacca ctacatcgtt
     7081 cctaaatttg aaaaagacac tcaagtaaaa ttggctggtc acaagatttt cgatgagttc
     7141 caagaagcca aagaacttgg attgaacact cgtcctgttc ttgtaggtcc cttcactttc
     7201 cttcaattgt cagactttga agaaggcgtg aaagcagacg acttcgtaga tagcttagtg
     7261 gctgcttacc aagaagtttt tgctaaattg gctgaacttg gtgcgactcg catccaattg
     7321 gatgaagcgg ctcttgtaaa agacttgaca gctgaagaaa aagctctctt cttgaacctt
     7381 tacaacaaac tcttggctga caaaaaaggt cttgaagtct tgcttcaaac ttatttcggt
     7441 gatgttcgtg acgtatacgc tgaccttgta aacttaccag tagatgctat cggtcttgac
     7501 tttgttgaag gtaagaaaac tcttgaactc gttaaaggtg gcttcccagc tgacaagact
     7561 ctctatgtag gtattgtcaa tggtaaaaac atctggcgca acaactacga aaagagcttg
     7621 actgttcttg agcaaatccc agctgaaaac atcgttttga caagctcttg ctcacttctt
     7681 catgtgccat ttacaactgc taatgaagaa tttgaaccag cactcttgaa ccactttgcc
     7741 tttgcagttg aaaaattgga tgaaatccgt gacttggatg ctatccgcaa tggtcaaggt
     7801 tcagaagctc ttgcagccaa caaagaactc tttgcgactg agcgtgttgg tgaaaatgct
     7861 gaacttcgtg cgcgtatcgc tggcttgaca gacgcagact acactcgttt gccagccttt
     7921 gcagaacgtg aagctatcca agaagaagct ttcaaacttc cagctcttcc aacaacaacg
     7981 attggttcat tccctcaaac aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt
     8041 gaattgtctc aaaaagagta cgatgctttc cttgctgaaa cgattgacga atggatcaag
     8101 tggcaagaag atattgactt tgatgtcctt gttcacggtg aatttgagcg taatgacatg
     8161 gttgagtact tcggtcaaaa cttgtcagga tacctcttct ctaaaaatgg atgggtacaa
     8221 tcatacggta tgcgtggggt aaaaccacca atcatctggg gtgatgtcac tcgtcttaac
     8281 cctatcactg ttaaatggtc tagctatgca caaagtcgta caaacaaacc tgttaaaggt
     8341 atgttgactg gacctgttac catccttaac tggtcattcc cacgtgaaga catctctatc
     8401 aaggattcaa ctcttcaaat cgcccttgct atcaaggatg aagtacttga ccttgaagtt
     8461 gctggtgtga agattatcca aatcgatgag gctgctcttc gtgaaaaatt gccactccgt
     8521 cgtagcgact ggtacgaaga ctaccttgac tgggcaattc ctgccttccg cttggtacac
     8581 tcaacagtag cgccagacac acaaatccac actcacatgt gttactcaga atttacagat
     8641 atcatcccag ctatcgataa catggatgca gacgttattt cctttgaagc tagccgttca
     8701 aaccttgaaa tcttggacga actcaaagcg aaaaacttcc aaacagaagt gggacctggg
     8761 gtttacgata tccactcacc tcgtgtacca aatgaaggcg aaatcgacaa cacaatcgaa
     8821 gccatccttg ctaaagtgcc aagcaagaaa gtttggatca accctgactg tggtttgaaa
     8881 acacgtggta tcccagaaac aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct
     8941 gcgcgtgaga aattgtaaga ttggatttct ctccatacag tggttgttca aaaagaaatc
     9001 aactagaaaa ggttattaca tatgtcacgc caaacaccgt cactctcatt tgaagtgttc
     9061 cctccaaacc cagccgtggg taatggtaac attatttcag ccttgcagga tatgcaggag
     9121 ttggctcccc attttatcag tgtaactgcc agcaataata aatttaatat caaggaaacg
     9181 acggttcgtt tggctgactt tatccaaaat gacttggcga ttccgaccat tgcccacttg
     9241 ccagctattt atctaactaa ggacaaggtt gctgaaacta ttgctgactt ggacaaagtt
     9301 ggggtgcaga aaatcttggc tcttcgtggg gatattattc cagacgtaga accacaaaag
     9361 gatttccgct atgcaaccga cttgattgag tttatcaagg aacaagcccc tcactttgat
     9421 attattggag cttgctatcc agaagggcat ccagattcgc caaatcagat ttcagatatt
     9481 caaaatctta agaagaaagt ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt
     9541 gacaatgagc gcttctatga ttttcaggac aagtgtatct tggctgggat tgatgttccc
     9601 attcatgcag gaattatgcc aattctgaat cgaaatcagg ctctccgact cttgaagact
     9661 tgtgagaata tccatcttcc acgcaaattt aaagccatct tagacaagta tgagcatgac
     9721 cctgagtcgc tcagagcagc aggacttgcc tatgcagtgg accaaatcgt ggacttggta
     9781 actcaggatg ttgccggtgt gcatctctat acgatgaata atgctgatac agcaaaatac
     9841 atccatcaag caacccatgc cttgtttaat caccagtctc taggataata aaagcaaacc
     9901 attcttctca ggtgagggga atggttcctt tttaatggta aagacctcac tttttaagaa
     9961 aaatatgata aaataaattc tgtacgtact tgatacaaag atgaaggtat taaataatac
    10021 aatgcattta aactgtaaga tttaacgaca cgagtgagtc aaatcgatgt tatttgacga
    10081 gagagttagt aaagcattta gctaatcgcc cgatagcgat tagcgtgaaa gctttagata
    10141 ctttagtatt aaacctttct aatgatgtat cttgaaaact gaacttgcct acaactctgt
    10201 ggaaaaagat aaatctccct aggagtagtc gctccgtcgt tcgatttcct atcttccttt
    10261 gagttgcttg acggcttggt atcttgatga cttgaatttt ggtctcattt cttaggaaaa
    10321 aagataagct tcctagcact cgtcgagtgt gacgtcacct tcctattttt ctacagaaat
    10381 gttcggcaag ccgaaccgtc caaaatatct tgtgtaattg aacacggccg aaaagctgtg
    10441 taaaaaagat aaactgtctt gtcttcatcg aagacttcgt cagtttccta tttttacttt
    10501 gcttttgacg tccttggtat cttgatcttt gtaggcaagg cgtataattt catcaatcca
    10561 aaggggatta aaatggcaaa acaagtgttt caaacgactt ttgcgggtcg tgagttaatt
    10621 gtagaaactg gtcaggttgc taagcaagca aatggctctg ttgtcgtacg ttacggtgag
    10681 tcaactgtct tgactgctgc cgttatgtct aagaaaatgg caactgggga tttcttccca
    10741 ctccaagtca actacgaaga aaaaatgtat gcggctggga agtttcctgg tggctttatg
    10801 aaacgtgaag gacgtccttc aacagatgcg accttgacag cgcgtttgat tgaccgtccg
    10861 attcgtccta tgtttgcgga aggtttccgt aatgaagtcc aagtcatcaa tacagtgctt
    10921 tcttatgatg aaaatgcatc tgcaccaatg gctgctatgt ttggttcatc tttggcactg
    10981 tctatttcag atattccatt tgacggacca attgctgggg tacaagtggg atatgtagat
    11041 ggccaaatca tcatcaaccc aagtcaagaa caagcagagc aatctcttct tgaattgaca
    11101 gtagctggaa ccaagcacgc tatcaacatg gtagagtctg gtgccaaaga attgtcagaa
    11161 gaaatcatgt tggaagcgct tcttaaaggg cacgaagctg tcaaagaatt gattgccttc
    11221 caagaagaaa tcgttgctgc tgtcggtaaa gaaaaagcag aagtggaatt gcttcacgtg
    11281 gatgctgaat tgcaagctga aatcattgca gcctacaaca gtgacctcca aaaggcagtt
    11341 caagtagaag agaaattggc ccgtgaagct gcaactcaag cagtgaaaga ccaagtgact
    11401 gccgtttacg aagaaaaata tgcgaaccac gaagaatttg accgtattat gcgtgatgtg
    11461 gctgaaatct tggaacaaat ggaacacgca gaagtgcgac gtttaattac agaagacaag
    11521 gtgcgtcctg atggtcgtaa ggtcgatgaa atccgtcctt tggatgcggt tgttgacttc
    11581 cttcctcgtg tacatggttc aggtctcttt actcgtgggc aaactcaagc tctttcagtc
    11641 ttgaccttgg ctccgatggg agaaactcaa atcattgatg gtttggatcc agagtacaag
    11701 aaacgcttta tgcaccacta taacttccct caatattctg taggggaaac aggtcgttac
    11761 ggtgcgccag gtcgtcgtga aatcggtcac ggtgcccttg gtgagcgtgc tcttgctcaa
    11821 gtcttgccaa gcttggaaga attcccatac gctatccgtc tagtagcaga agttttggaa
    11881 tcaaacggtt cttcatctca agcttctatc tgtgcgggaa ctcttgccct tatggctggt
    11941 ggtgtgccaa tcaaggcgcc agtagctggt attgctatgg gacttatctc agatggaaat
    12001 aactacacag tattgacaga tatccaaggt ttggaagatc actttggaga tatggacttc
    12061 aaggttgcag gtactcgtga tgggattaca gcccttcaaa tggatatcaa gattcaaggg
    12121 attactgcag aaatcttgac ggaggctctt gctcaagcca agaaagcgcg ttttgaaatc
    12181 cttgatgtca ttgaagcaac cattccagaa gttcgtccag aattggctcc aactgctccg
    12241 aaaattgata cgatcaagat tgatgtggac aagattaaga ttgtcatcgg taagggtgga
    12301 gaaaccatcg acaagattat cgctgaaaca ggtgttaaga ttgatataga cgaagaagga
    12361 aatgtgtcta tctactctag tgaccaagat gctattaacc gtgccaaaga aattattgct
    12421 ggtttggttc gtgaagccaa agtggatgaa gtttaccgtg ctaaagtcgt tcgtatcgag
    12481 aaatttggtg cctttgttaa cctctttgat aagacagatg cccttgttca tatctctgag
    12541 atggcttgga ctcgtaccaa tcgtgtagag gatttggtag aaatcgggga tgaagttgat
    12601 gttaaggtta tcaaaattga tgaaaaaggc cgtatcgatg cctctatgaa ggctcttcta
    12661 cctcgtccgc caaaacctga gcatgatgaa aaaggtgaaa agtctgagcg ccctcaccgc
    12721 ccacgtcatc aaaaggatta caaacctaag aaagaattta cagaaacatc aaaagattca
    12781 gaataagaaa aggagaaatg tatggggtgg tggcgcgaaa ccattgatat tgtaaaagaa
    12841 aatgatccag cggcccgcac cactttggag gttttgctga cttatccagg tgtcaaggcc
    12901 ttggcggccc accgtctctc gcattttctc tggaagcacg gcttcaaact attagctcgt
    12961 atgtacagtc agttttggcg cttttggact cagattgaga ttcatccagg agcccagatt
    13021 gattcaggtg tttttattga ccatggttct ggtctggtga ttggagagac agcgattgtt
    13081 gaaaaaggcg ttcttctcta tcacggagtg actctcgggg gaacagggaa agactgtggc
    13141 aaacgccatc cgactgtacg aaagggagcc ctcatatcag cccatgccca agttatcggg
    13201 cctgtggaaa ttggtgaaaa tgccaaggtc ggtgctgcag cagttgtcgt agcagatgta
    13261 cctagtgacg tgacggttgt cggtattccg gccaagattg tccgtcttca tggtaagaaa
    13321 gatgagcctg tcattcacga agtcgaagaa aaacgagagt attatgtcaa taaactcgag
    13381 caggctaaag atgccagtca cagatcgtct ggtttgtaga ggatacctat atgattcaag
    13441 caagaaacaa gttaagccaa gaggagctat ctgaggcgaa aaaagtaatt aactgttgcc
    13501 aaaactatga cggtacctat cgcgatccct atctctctaa catgcttaat tttgacccaa
    13561 acatgcccgc ctttttcctt tattatgaaa aaggcgaact tgttggttta ttaactgtct
    13621 atgcagatga ccaagatgta gaagtgacga tactggttca tccaggtcat cgccgtcagg
    13681 ggattgcgcg tgcattgttt actagttttg agagagaaac agcttctttc cccattcggt
    13741 cagtcacttt tcagacagaa cgtatttttt tagagaatca tcctgacttt gccagtaact
    13801 ggggactaat cgaggatgaa gagacagaaa cttggttagg taaggataga agaccttatc
    13861 cgttagcaaa tgtttcccat cttgaagttt tgttagcaga tagttcgtat caggatcaaa
    13921 ttagtcaatt aaaatttcag gcattttcag aggaacatga atcgagagaa gttgtggata
    13981 gatatgtcgc tgaagctctg aaagatccag aaagccgact atatatttta ttaaaagctg
    14041 gtcaggttat tggaacttgt acggttgatt tatcgactaa tacgaattac ctctacggtt
    14101 tagcaatatt ggaacctgaa cgtggaaaag gctatggaag ctacttagca aaatccctcg
    14161 tcaaccaact aattgagcaa aatgacaagg aatttcagat tgcagtggaa gatagcaatg
    14221 taggtgccaa acgtttgtat gaaaaaattg gctttgtcaa acagactcag gtggtttatc
    14281 tgaatgagaa aggagcaagg gattccgaag tgtagagata ttcggactga aatttacttg
    14341 aacttttagt gatgaaacta attgttcttg gatttcagct ttcctgatta tgatttatga
    14401 ttaaaatcta tgacaccatg tctcgtgatt tgcgagaatt tgtcccgatt gaggacggca
    14461 agatcaagat gtatgtttgt gggccaacgg tgtacaacta tatccacgta ggaaacgccc
    14521 gttcgacggt agcttttgat acgattcgtc gctattttga gtaccgtggg tataaggttg
    14581 cctatatttc caattttaca gatgtggatg ataagattat caaccgtgcc agggaagaag
    14641 gtatcacgcc tcaggaggtt gcggataagt acatcgctgc ctttcgtgag gatgtgacgg
    14701 ccttaggcgt gaaacctgcg actcgccatc cgcgtgtagt ggagtttatg gcagacatca
    14761 tccgttttgt ggaagacttg atcgagaaag gctttgccta tgagagtcaa ggggatgtct
    14821 atttccgtgt agaaaaatcc cacaactatg ctaaattggc taataaaacc ttggaagatt
    14881 tggagctagg tgcttcaggt cgtaccgatg aagaaacggc tcgtaaggaa aatcctgtag
    14941 actttgctct atggaaatct tccaaaccag gtgagatttc ttgggatagt ccttggggac
    15001 ctggacgtcc gggttggcat attgagtgtt cagtcatgtc gacagagatt ttaggtgata
    15061 ccattgatat ccacggtggt ggagctgacc tagagtttcc acaccacacc aatgaaattg
    15121 cccagtctga agctaaaaca ggcaaggctt ttgctaacta ctggatgcac aatggctttg
    15181 tcaatatcga caatgtcaaa atgtctaagt ccttgggtaa cttcattacg gtacacgatg
    15241 cccttaaaac tcttgatggg caagtacttc gtttcttctt tgcgacccag cactaccgta
    15301 agcctatcaa cttcacggaa aaggcagttc gcgatgccga gaccaatctc aagtatctca
    15361 agaatactta cgaacaacca tttacaggaa atgtggatgc ccaagagtta caaaacttta
    15421 aagataagtt tgtagcagct atggatgaag attttaatgc tgccaacggt atcacagttg
    15481 tctttgaaat ggccaaatgg atcaactcag ggaactatga tgcaagtgtc aagcaagctc
    15541 ttgcagatat gttagaaatt tttggaattg tctttgttga ggaagttttg gatgcagaga
    15601 ttgaagactt gattcaaaaa cgccaagagg cgcgtgccaa tcgtgacttt gcgacagcag
    15661 accaaatccg tgaccaattg gttactcaag gaattaagct ccttgatacc aaggatggag
    15721 tgaggtggac acgtgattga tgtcaatctc attaacggga ttgcgctagc ctttgagggg
    15781 gatgcggtgt attctatgta tattcgccgt cacctcatcc tcaaaggtat gaccaaaccc
    15841 aataaactcc atcaagaagc aactaagtac gtgtcagcca aggctcaggc tcgcctgatt
    15901 gctctcatgt tggaggagca ggtcctaacg gaaaaagaag aagaaatcta caaacgtggc
    15961 cgcaatacca atagccacac aaaggctaaa aatgcagatg tcgtgactta tcgtatgtcc
    16021 acgggatttg aagcggttat gggctatctc catatgactg agaatctgga acgtcttgag
    16081 agtttggttt catggtgcat ccaaaaagtg gagggctaga acatgagggc aaaagaacta
    16141 caagactggt ttcctgaggc tcggatttca gaccaaccag tagagaaaga gggctatctc
    16201 acgctccctt tagcttctca gcagtggatt ttgctggagg aagctgggct cagcgagcgt
    16261 gaaaagcagt tggttgccct tttgacccag caggagcagg ctcgttcgct aaacccttgg
    16321 tattcctatc tggttgaggg caagggacag gcaccgcaag tttttaaaaa gattcagttg
    16381 gtttattgcc atctttctta ttttcagcag gaaaatctgg cttcttggct agatatgatg
    16441 cggactcttt ttccgaattg tcagacagtg ctacaggtcg gagctcagga ttatgttttc
    16501 gtgcttcaac aagacaaata cacttctgta agagatattt taagtgatac gattgaagcg
    16561 gttgagtatg actttggact tcgtctttct atcatgttgg gtcaggtttg gtctcagacg
    16621 ggacatcaag ccctatcaga cttaatcaaa gctgagcggg atttgttcaa gacatggtgg
    16681 cgtcagggtc accaaggtgt tcatactttt tctcagctct atctttggag tatgggagaa
    16741 agactcgtgg acttgaagcc aatcaaggaa tgtctacacc agatgatttt ggatcaagat
    16801 cagattcagg aaatcattct ctctctttgg gaaaatagtg ctgttctcac taaaacagcc
    16861 cagcaactct atctgcaccg caattctctc caatacaaga ttgataaatg ggaagagttg
    16921 acagggcttc agttgaaaga gttgaccgac ctgaccttgt gttatcaatt gattttaggt
    16981 tctttgtcaa ctatagttgg tttgtaaaga agttaatatt tggagaagag gattgccatc
    17041 ttctccattt ttatgtgcag agttatagtg gcttgatgct gggaaagtac actgtgactg
    17101 ctaaaacatt cctagaagct gctttgattt ccctaatcta tttatgcaaa ttttatgtta
    17161 ttttactata acagttgttg ctaagccaaa taatagtggg gaagttcatt tagacgtaag
    17221 cattgaagat aatcagggag gtagtgggta taatttcagt tctgtttcaa gtagctcaca
    17281 aacagctaaa tatgaaggaa ctgtttataa taacaattca tcattatata taacgattga
    17341 taaaacgtct gatgcaacag ctcttttgaa attaaagttg aataatgttg ataatcaacc
    17401 tgctactgaa gttcctagtt caggaattac tgtaaaatta aatgctaaag ataatgctgg
    17461 aaactggaca agtgcttcga ataaaaaaga aataacagta aaaattgttt ctgctaaacc
    17521 gacatatcca gacaaaatct tagtgaaaaa tcctgataat ataaaagata cagaaaaaat
    17581 gccattattg aaaaattgaa agaggcaaat aaaaatcatc cagcaggagc tccaaccttt
    17641 gctaaaggtg aaggagagca tgcaaatgat attgtagcaa cttattcaga tggtacaact
    17701 tattatgtac cgttaaatga tgtgacaaaa tatgcgaggt agtggctgta ccactcactt
    17761 attcacctcc ccgtgatttg tagtagtgat aggctttctc actattatta taaaacaaaa
    17821 taaagatcac aacacttttt cattctgtgt tgtgccttga gtgaaacgaa aggaatgaat
    17881 tataaatatg aaaagtatag tcactagcat agatgagcgc ttgcgtactc gcctacgagt
    17941 gattatctgg aagcaatgga agaagaaatc gagacgatta tggggattgc ttaagttagg
    18001 ggttcctaaa tggatagcag ataaggtatc tggctggggc gaccactatc aattatatta
    18061 aaatgaaata agaataggac gaatcgatca gggaagtcaa atcgatttct aacaatattt
    18121 tagaagtaga ggtatattat tctagtttca atctactata gtatctcaga agtcggtact
    18181 taaacgtgct atatcaaaac cagtccttg
//
LOCUS       DAVLHB010000043        17933 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLHB010000043 DAVLHB010000000
VERSION     DAVLHB010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.043"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(9..82)
                     /locus_tag="VXE36_001614"
     tRNA            complement(9..82)
                     /locus_tag="VXE36_001614"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46..48),aa:Arg,seq:tct)
     gene            complement(126..605)
                     /gene="rlmH"
                     /locus_tag="VXE36_001615"
     CDS             complement(126..605)
                     /gene="rlmH"
                     /locus_tag="VXE36_001615"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0779877.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            788..1969
                     /locus_tag="VXE36_001616"
     CDS             788..1969
                     /locus_tag="VXE36_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0779878.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            2027..2785
                     /locus_tag="VXE36_001617"
     CDS             2027..2785
                     /locus_tag="VXE36_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0779879.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            2998..4359
                     /gene="dnaA"
                     /locus_tag="VXE36_001618"
     CDS             2998..4359
                     /gene="dnaA"
                     /locus_tag="VXE36_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0779880.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            4518..5654
                     /gene="dnaN"
                     /locus_tag="VXE36_001619"
     CDS             4518..5654
                     /gene="dnaN"
                     /locus_tag="VXE36_001619"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0779881.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            5719..5913
                     /locus_tag="VXE36_001620"
     CDS             5719..5913
                     /locus_tag="VXE36_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0779882.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            5997..7112
                     /gene="ychF"
                     /locus_tag="VXE36_001621"
     CDS             5997..7112
                     /gene="ychF"
                     /locus_tag="VXE36_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0779883.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            7183..7752
                     /locus_tag="VXE36_001622"
     CDS             7183..7752
                     /locus_tag="VXE36_001622"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0779884.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            7753..11262
                     /gene="mfd"
                     /locus_tag="VXE36_001623"
     CDS             7753..11262
                     /gene="mfd"
                     /locus_tag="VXE36_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0779885.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEKNSI"
     gene            11320..11586
                     /locus_tag="VXE36_001624"
     CDS             11320..11586
                     /locus_tag="VXE36_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0779886.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            11579..11947
                     /locus_tag="VXE36_001625"
     CDS             11579..11947
                     /locus_tag="VXE36_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0779887.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            12067..13335
                     /locus_tag="VXE36_001626"
     CDS             12067..13335
                     /locus_tag="VXE36_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0779888.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            13332..14609
                     /gene="tilS"
                     /locus_tag="VXE36_001627"
     CDS             13332..14609
                     /gene="tilS"
                     /locus_tag="VXE36_001627"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0779889.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKFKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            14613..15155
                     /gene="hpt"
                     /locus_tag="VXE36_001628"
     CDS             14613..15155
                     /gene="hpt"
                     /locus_tag="VXE36_001628"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0779890.1"
                     /translation="MLENDIKKVLVSHDEITETAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            15171..17129
                     /gene="ftsH"
                     /locus_tag="VXE36_001629"
     CDS             15171..17129
                     /gene="ftsH"
                     /locus_tag="VXE36_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0779891.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            17251..17730
                     /locus_tag="VXE36_001630"
     CDS             17251..17730
                     /locus_tag="VXE36_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0779892.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRWRQRVLRDLRIVFKEFTIRTH"
     gene            17824..17895
                     /locus_tag="VXE36_001631"
     tRNA            17824..17895
                     /locus_tag="VXE36_001631"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17857..17859,aa:Glu,seq:ttc)
BASE COUNT         6222 a         2792 c         3531 g         5388 t
ORIGIN      
        1 tattatattg atcccagcag gattcgaacc tgcgaccgtt cgcttagaag gcgaatgctc
       61 tatccagctg agctatgaga cctaatacaa ttattctacc aaaaattcaa ttaaaagtca
      121 attttctatt tatggtaggg gaatccctgc tgaatcgtaa aagcgcgata gatttgttca
      181 acaagaacta gtctcattaa ctgatggggt aaggttaggc gaccaaaact gacagaaaga
      241 ttggctctat tttttacaga tgatgacaat cctaaacttc ccccaataat aaaagtaaga
      301 gtagaaaatc cttttataga agtttcttct aactgcttac taaattcttc tgagaagaaa
      361 gttttccctt caatggctaa cacaataacg aaatcacggt cagcaatttt tgataaaatt
      421 ctctgacctt ctatttctaa aatcttttga ttttctgatt cactggcctt atctggtgtt
      481 ttttcatctg ataactcaat catttcaaac ttagcaaatc tagaaattcg ttttgaatac
      541 tctgcgatac catcttttaa atacttttct ttcagtttcc caactgttac aactttaatt
      601 ttcatgactc tattctaaca tattctctat tttttcacat cttattcaca aaataaaaaa
      661 tagatttcaa ttaagaaaat cacagtttca aaagagttat ccacagtttg tgtaaaactt
      721 ttgtgtttaa gttataatta agctagtcag tttatacttt cagtaattca aacatatgga
      781 ggcaaatatg aaacatctaa aaacatttta caaaaaatgg tttcaattat tagtcgttat
      841 cgtcattagc ttttttagtg gagccttggg tagtttttca ataactcaac taactcaaaa
      901 aagtagtgta aacaactcta acaacaatag tactattaca caaactgcct ataagaacga
      961 aaattcaaca acacaggctg ttaacaaagt aaaagatgct gttgtttctg ttattactta
     1021 ttcggcaaac agacaaaata gcgtatttgg caatgatgat actgacacag attctcagcg
     1081 aatctctagt gaaggatctg gagttattta taaaaagaat gataaagaag cttacatcgt
     1141 caccaacaat cacgttataa atggcgccag caaagtagat attagattgt cagatgggac
     1201 taaagtacct ggagaaattg tcggagctga cactttctct gatattgctg tcgtcaaaat
     1261 ctcttcagaa aaagtgacaa cagtagctga gtttggtgat tctagtaagt taactgtagg
     1321 agaaactgct attgccatcg gtagcccgtt aggttctgaa tatgcaaata ctgtcactca
     1381 aggtatcgta tccagtctca atagaaatgt atccttaaga tcggaagatg gacaagctat
     1441 ttctacaaaa gccatccaaa ctgatactgc tattaaccca ggtaactctg gcggcccact
     1501 gatcaatatt caagggcagg ttatcggaat tacctcaagt aaaattgcta caaatggagg
     1561 aacatctgta gaaggtcttg gtttcgcaat tcctgcaaat gatgctatca atattattga
     1621 acagttagaa aaaaacggaa aagtgacgcg tccagctttg ggaatccaga tggttaattt
     1681 atctaatgtg agtacaagcg acatcagaag actcaatatt ccaagtaatg ttacatctgg
     1741 tgtagttgtt cgttcggtac aaagtaatat gcctgccaat ggtcaccttg aaaaatacga
     1801 tgtaattaca aaagtagatg acaaagagat tgcttcatca acagacttac aaagtgctct
     1861 ttacaaccat tctatcggag acaccattaa gataacctac tatcgtaacg ggaaagaaga
     1921 aactacctct atcaaactta acaagagttc aggtgattta gaatcttgat tgacatctat
     1981 gtaaagaaag ctttacataa gagaaaagat gtgttagtgt agaatcatgg aaaaatttga
     2041 aatgatttct atcacagata tacaaaaaaa tccctatcaa ccccgaaaag aatttgatag
     2101 agaaaaacta gatgaactag cacagtctat caaagaaaat ggggtcattc aaccgattat
     2161 tgttcgtcaa tctcctgtta ttggttatga aatccttgca ggagagagac gctatcgggc
     2221 ttcactttta gctggtctac ggtctatccc agctgttgtt aaacagattt cagaccaaga
     2281 gatgatggtc cagtccatta ttgaaaattt acagagagaa aatttaaacc caatagaaga
     2341 agcacgcgcc tatgaatctc tcgtagagaa aggattcacc catgctgaaa ttgcagataa
     2401 gatgggcaag tctcgtccat atatcagcaa ctccattcgt ttactttcct tgccagaaca
     2461 gattctttca gaagtagaaa atggcaaact atcacaagcc catgcgcgtt ccctagttgg
     2521 gttaaataag gaacaacaag actatttctt tcaacggatt atagaagaag atatttctgt
     2581 aaggaaatta gaagctcttc tgacagagaa aaaacaaaag aaacagcaaa aaactaatca
     2641 tttcatacaa aatgaagaaa aacagttaag aaaactactc ggattagatg tagaaattaa
     2701 actatctaaa aaagacagtg gaaaaatcat tatttctttt tcaaatcaag aagaatatag
     2761 tagaattatc aacagcctga aataaggctg ttcttttatt tttttatctc acaaggttat
     2821 ccactatgtt tttcgataaa aagcttaata aatcaataat ttcttctttt atccccaacc
     2881 tgtggataaa gtttggtaac attgtggatt atttttcaca gcttgtggaa aattcttgct
     2941 atctatggta aaatatctct agtattaaac ttttaaatag taaaggagga gaaaggattg
     3001 aaagaaaaac aattttggaa tcgtatatta gaatttgcac aagaaagact gactcgatcc
     3061 atgtatgatt tctatgctat tcaagctgaa ctcatcaagg tagaggaaaa tgttgccact
     3121 atatttctac ctcgctctga aatggaaatg gtctgggaaa aacaactaaa agatattatt
     3181 gtagtagctg gttttgaaat ttatgacgct gaaataactc cccactatat tttcaccaaa
     3241 cctcaagata cgactagctc acaagttgaa gaagctacaa atttaactct ttatgactat
     3301 agtccaaagt tagtatctat tccttattca gatacgggat taaaagaaaa gtataccttt
     3361 gataacttta ttcaagggga tggaaatgtt tgggctgtat cagccgcttt agctgtctct
     3421 gaagatttgg ctctgaccta taaccctctt tttatctatg gaggaccagg ccttggtaag
     3481 actcacttat taaacgctat tggaaatgaa attctaaaaa atattcctaa tgcgcgtgtt
     3541 aaatatatcc ctgccgaaag ctttattaat gactttcttg atcacctaag acttggggaa
     3601 atggaaaagt ttaaaaagac ctatcgtagt cttgatcttt tgttaatcga tgatatacag
     3661 tcactcagcg gaaaaaaagt cgcaactcag gaagaatttt tcaatacctt taacgccctt
     3721 catgacaagc aaaaacagat tgtcctaacg agtgatcgta gtccaaaaca tctagaaggg
     3781 ctcgaggaga ggcttgtcac gcgttttagt tggggattga cacaaactat cacaccccct
     3841 gactttgaaa cacgtattgc cattttacaa agtaagacgg aacatttagg ctacaatttc
     3901 caaagtgata ctctagaata cctagctggg caatttgatt caaatgttcg agatcttgag
     3961 ggagccatca acgacatcac tttaattgcc agagtaaaaa aaatcaagga tatcactatt
     4021 gatattgctg cagaagccat tagagcccgc aaacaagatg ttagccaaat gctcgtcatc
     4081 ccaattgata aaatccaaac tgaagttggt aacttttatg gtgttagtat caaagaaatg
     4141 aagggaagta gacgccttca aaatattgtt ttggcccgtc aagtagccat gtatttatct
     4201 agagaactaa cagataatag tcttccaaaa attgggaagg aatttggggg aaaagatcat
     4261 accacagtca ttcatgccca tgccaaaata aaatctttga ttgatcaaga cgataattta
     4321 cgtttagaaa ttgaatcaat caaaaagaaa atcaaataat ttgtggataa cttttagttt
     4381 tttatctttt ttatccacat tttttaaaca agctaaaaaa cttgatatga cttgtttaaa
     4441 ggctgttttc cacagatttc acagactcta ttattactat tatctttcta atactaaaaa
     4501 taaataaagg agaatccatg attcattttt caattaataa aaatttattt ctacaagcat
     4561 taaatactac taagagagct attagttcta aaaatgccat tcctatttta tcaacagtaa
     4621 aaattgacgt gaccaatgaa ggtattactt taattggttc aaatggtcaa atttcaattg
     4681 aaaattttat ttctcaaaaa aatgaagatg ctggtttgtt aattacttct ttaggttcga
     4741 tccttcttga agcttctttc tttatcaatg tagtatctag tttacctgat gtaactcttg
     4801 attttaaaga aattgaacaa aatcaaattg ttttaaccag tggcaaatca gaaattaccc
     4861 taaaaggaaa agatagcgaa caatatccac gaatccaaga aatttcagca agcactcctt
     4921 taatacttga aacaaaatta ctcaagaaaa ttattaatga aacagccttt gctgcaagta
     4981 cacaagagag tcgtccgatt ttaacaggtg tccacttcgt attgagtcaa cacaaagagt
     5041 taaaaacagt tgcaacagac tctcatcgcc taagccagaa aaaattgact cttgaaaaaa
     5101 atagtgatga ttttgatgtc gtaattccta gccgttctct acgcgaattt tcagcggtat
     5161 ttacagatga tatcgaaact gtagagattt tctttgccaa taaccaaatc ctctttagaa
     5221 gcgaaaatat tagcttctat actcgtctcc tagaaggaaa ctatcctgat acagatcgct
     5281 tgattccaac agactttaac actactatta cttttaatgt ggtaaactta cgccagtcaa
     5341 tggagcgtgc ccgtctttta tcaagtgcga ctcaaaatgg tactgtgaaa cttgaaatta
     5401 aggatggggt tgttagcgcc catgttcact ctccagaagt tggtaaagta aacgaagaaa
     5461 tcgatactga tcaggttact ggtgaagatt tgaccattag tttcaaccca acttacttga
     5521 ttgattctct taaagcttta aatagcgaaa aggtgactat tagctttatc tcagctgttc
     5581 gtccatttac tcttgtgcca gcagatactg acgaagactt catgcagctc attacaccag
     5641 ttcgtacaaa ttaagtgaaa gaggttgagc ctggctcgcc tcttttatga tataatcgaa
     5701 aaagaaaagg agagtagtat gtatcaagtt ggaaattttg ttgagatgaa aaaatcacac
     5761 gcttgtacaa tcaagtcgac tggtaaaaag gctaatcgtt gggaaattac acgtgtagga
     5821 gcagatatca aaataaaatg tagtaattgt gagcatgttg tcatgatggg gcgatatgat
     5881 tttgagcgaa aaatgaataa aattattgac tgagaaccct tagttagagg gttagcactt
     5941 tatccctttt tgtgttataa tattagggat tgaaatgaaa acggagaatg agaaatatgg
     6001 ctttgacagc aggtatcgtt ggtttgccaa acgttggtaa atcaacacta tttaatgcaa
     6061 ttacaaaagc aggagcagag gcagcaaact acccatttgc gactattgat ccaaatgttg
     6121 gaatggtgga agttccagat gaacgcctac aaaaactaac tgaaatgata actcctaaaa
     6181 agacagttcc cacaacattt gaatttacgg atattgcagg gattgtaaaa ggagcttcaa
     6241 aaggagaagg gctagggaat aaattcttgg ccaatattcg tgaagtagat gcgattgttc
     6301 acgtagttcg tgcttttgat gatgaaaatg tgatgcgcga gcaaggacgt gaagacgcct
     6361 ttgtagatcc acttgcagat attgatacaa ttaatctgga attaattctt gctgacttag
     6421 aatcagtgaa caaacgatat gcgcgtgtag aaaagatggc acgtacgcaa aaagataaag
     6481 aatcagtagc agaatttaat gttcttcaaa agattaaacc agtcctagaa gacgggaaat
     6541 cagctcgtac cattgaattt acagatgagg aacaaaaggt tgtcaaaggt cttttccttt
     6601 tgacgactaa accagttctt tatgtagcta atgtggacga ggatgtggtt tcagaacctg
     6661 actctatcga ctatgtcaaa caaattcgtg aatttgcagc gacagaaaat gctgaagtag
     6721 tcgttatttc tgcgcgtgct gaggaagaaa tttctgaatt ggatgatgaa gataaaaaag
     6781 agtttcttga agccattggt ttgacagaat caggtgtaga taagttgacg cgtgcagctt
     6841 accacttgct tggattggga acttacttta cagctggtga aaaagaagtt cgcgcttgga
     6901 ctttcaaacg tggtatgaag gctcctcaag cagctggtat tatccactca gactttgaaa
     6961 aaggctttat tcgtgcagta accatgtcat atgaagatct agtgaaatac ggatctgaaa
     7021 aggccgtaaa agaagctgga cgcttgcgtg aagaaggaaa agaatatatc gttcaagatg
     7081 gcgatatcat ggaattccgc tttaatgtct aaaaattaat aaatggtgtc aattaggttg
     7141 gaaaaaaatt ccaacccttt tggcttttga aaggaaaaat aaatgaccaa attacttgta
     7201 ggcttgggaa atccagggga taaatatttt gaaacaaaac acaatgttgg ttttatgttg
     7261 attgatcaac tagcgaagaa acagaatgtc acttttacac acgataagat atttcaagct
     7321 gacctagcat cctttttcct aaatggagaa aaaatttatc tggttaaacc aacgaccttt
     7381 atgaatgaaa gtggaaaagc agttcatgct ttattaactt actatggttt ggatattgac
     7441 gatttactta tcatttacga tgatcttgac atggaagttg ggaaaattcg tttaagagca
     7501 aaaggctcag caggtggtca taatggtatc aagtctatta ttcaacatat aggaactcag
     7561 gtctttaacc gtgttaagat tggaattgga agacctaaaa atggtatgtc agttgttcat
     7621 catgttttga gtaagtttga cagggatgag tatatcggta ttttacagtc tgttgacaaa
     7681 gttgacgatt ctgtaaacta ctatttacaa gagaaaaatt ttgagaaaac aatgcagagg
     7741 tataacggat aaatggtgac cttattagat ttattctcag aaaatgatca gattaaaaaa
     7801 tggcatcaaa atttaacaga taagaaaaga caactaatac ttggtttatc aacatctact
     7861 aaggctcttg caattgcaag cagtttagaa aaagaagata ggattgtgtt attgatgtca
     7921 acttatggag aagcagaagg acttgttagt gatcttatat ctatcttggg tgaggaactc
     7981 gtctatccat ttttggtaga tgatgctcct atggtggagt ttttgatgtc ttcacaggaa
     8041 aaaattattt cacgggttga agccttgcgt tttttgactg attcatctaa gaaagggatt
     8101 ttagtttgta atatcgcagc aagtcgattg attttaccgt ctcccaatgc attcaaagat
     8161 agtattgtaa aaatctcagt tggtgaagaa tatgatcaac acgcgtttat ccatcagtta
     8221 aaggaaaatg gctatcgaaa agttactcaa gtacaaactc agggcgaatt tagtcttcga
     8281 ggagatattt tagatatttt tgaaatatcc cagttagaac cttgtcgaat tgagtttttt
     8341 ggtgatgaaa ttgatggtat caggtcattt gaagtagaaa cacaattatc gaaagaaaat
     8401 aagacagaac tcactatctt tccagctagt gatatgcttt tgagagaaaa ggattatcaa
     8461 cgaggacagt cagctttaga aaaacaaatt tcaaaaactt tatcacctat tttgaaatca
     8521 tacctagaag aaattctttc aagttttcac caaaaacaaa gtcatgcaga ctctcggaag
     8581 tttttatctt tgtgctatga taagacatgg actgtctttg attatattga aaaagatact
     8641 ccaatattct ttgatgatta tcaaaaattg atgaatcagt atgaagtctt tgaaagagaa
     8701 ttagcgcagt actttacaga agaattacag aatagtaaag cattttctga tatgcagtat
     8761 ttttctgata ttgaacaaat ctataaaaaa caaagtccag tgaccttttt ttctaatctt
     8821 caaaagggtt taggaaatct caaatttgac aaaatttatc aattcaatca atatcctatg
     8881 caggaatttt tcaatcagtt ttcttttcta aaagaagaaa ttgaacgata taaaaaaatg
     8941 gattacacca ttattctgca gtctagcaat tcaatgggaa gtaaaacatt ggaggatatg
     9001 ttagaggaat atcagattaa attggattct agagataaga caaatatctg taaagaatct
     9061 gtaaacttaa tagagggtaa tctcagacat ggttttcatt ttgtagatga aaagatttta
     9121 ttgataactg aacatgagat ttttcaaaag aaattaaagc gtcgttttcg aagacaacat
     9181 gtttcaaatg cagagagatt aaaagattac aatgaacttg aaaaagggga ctatgttgtc
     9241 catcatatcc atgggattgg tcaatatcta ggaattgaaa ccattgaaat caagggaatt
     9301 catcgtgatt atgtcagtgt ccaataccaa aatggtgatc aaatttctat tcccgtggaa
     9361 cagattcatc tactgtccaa atatatttca agtgatggta aagctccaaa actcaataaa
     9421 ttaaatgacg gtcattttaa aaaggccaag caaaaggtta agaaccaggt agaggatata
     9481 gctgatgatt taatcaaact ctactctgaa cgtagtcagt tgaagggttt tgctttctca
     9541 gctgatgatg atgatcaaga tgcctttgat gatgctttcc cttatgttga aacggatgat
     9601 caacttcgta gtattgagga aatcaagagg gatatgcagg cttctcagcc aatggatcga
     9661 cttttagttg gggatgttgg ttttggaaag actgaagttg ctatgcgtgc agcctttaaa
     9721 gcagtcaatg atcacaaaca ggttgtcatt ctagttccga cgacggtttt agcgcaacag
     9781 cactatacga attttaagga acgattccaa aattttgcag ttaatattga tgtgttgagt
     9841 cgctttagaa gtaaaaaaga gcagactgca acacttgaaa aattgaaaaa cggtcaagtc
     9901 gatattttga ttggaacaca tcgtgttttg tcaaaagatg ttgtgtttgc tgatttgggc
     9961 ttgatgatta ttgatgagga acagcgattt ggtgtcaagc ataaggaaac tttgaaagaa
    10021 ctgaagaaac aagtggatgt cctaaccttg accgctacgc caatccctcg taccctccat
    10081 atgtctatgc tgggaatcag agatttatct gttattgaaa ctccgccgac taatcgctat
    10141 cctgttcaga cctatgtttt ggaaaagaat gatagtgtca ttcgtgatgc tgtcttgcgt
    10201 gaaatggagc gtggaggtca agtttattat ctttacaaca aagttgacac aattgttcag
    10261 aaggtttcag aattacagga gttgattccg gaggcttcga ttggatatgt tcatggtcga
    10321 atgagtgaag tccagttgga aaatactcta ttagacttta ttgagggaca atacgatatc
    10381 ttggtgacga ctactattat tgagacaggg gtggacattc caaatgctaa tactttattt
    10441 attgaaaatg cggaccatat gggcttgtca accttatatc agttaagagg aagagtcggt
    10501 cgtagtaatc gtattgctta tgcttatctc atgtatcgtc cagaaaaatc aatcagtgaa
    10561 gtctctgaaa agagattaga agcgattaaa ggatttacag aattgggctc tggctttaag
    10621 attgcaatgc gagatctttc gattcgtgga gcaggaaatc ttttaggaaa atcccagtct
    10681 ggtttcattg attctgttgg ttttgaattg tattcgcagt tattagagga agctattgct
    10741 aaacgaaacg gtaatgctaa cgctaacaca agaaccaaag ggaatgctga gttgattttg
    10801 caaattgatg cctatcttcc tgatacttat atttctgatc aacgacataa gattgaaatt
    10861 tacaagaaaa ttcgtcaaat tgacaaccgt gtcaattatg aagagttaca agaggagttg
    10921 atagaccgtt ttggagaata cccagatgta gtagcctatc ttttagagat tggtttggtc
    10981 aaatcatact tggacaaggt ctttgttcaa cgtgtggaaa gaaaagataa taaaattaca
    11041 attcaatttg aaaaagtcac tcaacgactg tttttagctc aagattattt taaagcttta
    11101 tccgtaacga acttaaaagc aggcatcgct gagaataagg gattaatgga gcttgtattt
    11161 gatgtccaaa ataagaaaga ttatgaaatt ttagaaggtc tgctgatttt tggagaaagt
    11221 ttattagaga taaaagagtc taaggaaaaa aattccattt gatatttttc ttctataaaa
    11281 tagataaaaa tggtacaata ataaattgag gtaataagga tgagattaga taaatattta
    11341 aaagtatcgc gaattatcaa gcgtcgtaca gtcgcaaagg aagtagcaga taaaggtaga
    11401 atcaaggtta atggaatctt ggccaaaagt tcaacggact tgaaagttaa tgaccaagtt
    11461 gaaattcgct ttggcaataa gttgctgctt gtaaaagtac tagagatgaa agatagtaca
    11521 aaaaaagaag atgcagcagg aatgtatgaa attatcagtg aaacacgggt agaagaaaat
    11581 gtctaaaaat attgtacaat tgaataattc ttttattcaa aatgaatacc aacgtcgtcg
    11641 ctacctgatg aaagaacgac aaaaacggaa tcgttttatg ggaggggtat tgattttgat
    11701 tatgctatta tttatcttgc caacttttaa tttagcgcag agttatcagc aattactcca
    11761 aagacgtcag caattagcag acttgcaaac tcagtatcaa actttgagtg atgaaaagga
    11821 taaggagaca gcatttgcta ccaagttgaa agatgaagat tatgctgcta aatatacacg
    11881 agcgaagtac tattattcta agtcgaggga aaaagtttat acgattcctg acttgcttca
    11941 aaggtgataa aatggaaaat ttattagacg taatagagca atttttgagt ttgtcagatg
    12001 aaaagctgga agaattggct gataaaaatc aattattgcg tttacaagaa gaaaaggaaa
    12061 ggaagaatgc gtaaattctt aattattttg ttgctaccaa gttttttgac catttcaaaa
    12121 gtcgttagca cagaaaaaga agtcgtctat acttcgaaag aaatttatta cctttcacaa
    12181 tctgactttg gtatttattt tagagaaaaa ttaagttctc ccatggttta tggagaggtt
    12241 cctgtttatg cgaatgaaga tttagtagtg gaatctggga aattgactcc caaaacaagt
    12301 tttcaaataa ccgagtggcg cttaaataaa caaggaattc cagtatttaa gctatcaaat
    12361 catcaattta tagctgcgga caaacgattt ttatatgatc aatcagaggt aactccaaca
    12421 ataaaaaaag tatggttaga atctgacttt aaactgtaca atagtcctta tgatttaaaa
    12481 gaagtgaaat catccttatc agcttattcg caagtatcaa tcgacaagac catgtttgta
    12541 gaaggaagag aatttctaca tattgatcag gctggatggg tagctaaaga atcaacttct
    12601 gaagaagata atcggatgag taaagttcaa gaaatgttat ctgaaaaata tcagaaagat
    12661 tctttctcta tttatgttaa gcaactgact actggaaaag aagctggtat caatcaagat
    12721 gaaaagatgt atgcagccag cgttttgaaa ctctcttatc tctattatac gcaagaaaaa
    12781 ataaatgagg gtctttatca gttagatacg actgtaaaat acgtatctgc agtcaatgat
    12841 tttccaggtt cttataaacc agagggaagt ggtagtcttc ctaaaaaaga agataataaa
    12901 gaatattctt taaaggattt aattacgaaa gtatcaaaag aatctgataa tgtagctcat
    12961 aatctattgg gatattacat ttcaaaccaa tctgatgcca cattcaaatc caagatgtct
    13021 gccattatgg gagatgattg ggatccaaaa gaaaaattga tttcttctaa gatggccggg
    13081 aagtttatgg aagctattta taatcaaaat ggatttgtgc tagagtcttt gactaaaaca
    13141 gattttgata gtcagcgaat tgccaaaggt gtttctgtta aagtagctca taaaattgga
    13201 gatgcggatg aatttaagca tgatacgggt gttgtctatg cagattctcc atttattctt
    13261 tctattttca ctaagaattc tgattatgat acgatttcta agatagccaa ggatgtttat
    13321 gaggttctaa aatgagggaa ccagattttt taaatcattt tctcaagaag ggatatttca
    13381 aaaagcatgc taaggcggtt ctagctcttt ctggtggatt agattctatg tttctattta
    13441 aggtattgtc tacttatcaa aaagagttag agattgaatt gattctagct catgtgaatc
    13501 ataagcagag aattgaatca gattgggaag aaaaggaatt aaggaagttg gctgctgaag
    13561 cagagcttcc tatttatatc agcaattttt caggagaatt ttcagaagcg cgtgcacgaa
    13621 attttcgtta tgattttttt caagaggtca tgaaaaagac aggtgcgaca gctttagtca
    13681 ctgcccacca tgctgatgat caggtggaaa cgatttttat gcgcttgatt cgaggaactc
    13741 gcttgcgcta tctatcagga attaaggaga agcaagtagt cggagagata gaaatcattc
    13801 gtcccttctt gcattttcag aaaaaagact ttccatcaat ttttcacttt gaagatacat
    13861 caaatcagga gaatcattat tttcgaaatc gtattcgaaa ttcttactta ccagaattgg
    13921 aaaaagaaaa tcctcgattt agggatgcaa tcttaggcat tggcaatgaa attttagatt
    13981 atgatttggc aatagctgaa ttatctaaca atattaatgt ggaagattta cagcagttat
    14041 tttcttactc tgagtctaca caaagagttt tacttcaaac ttatctgaat cgttttccag
    14101 atttgaatct tacaaaagct cagtttgctg aagttcagca gattttaaaa tttaaaagcc
    14161 agtatcgtca tccgattaaa aatggctatg aattgataaa agagtaccaa cagtttcaga
    14221 tttgtaaaat cagtccgcag gctgatgaaa aggaagatga acttgtgtta cactatcaaa
    14281 atcaggtagc ttatcaagga tatttatttt cttttggact tccattagaa ggtgaattaa
    14341 ttcaacaaat acctgtttca cgtgaaacat ccatacacat tcgtcatcga aaaacaggag
    14401 atgttttgat taaaaatggg catagaaaaa aactcagacg tttatttatt gatttgaaaa
    14461 tccctatgga aaagagaaac tctgctctta ttattgagca atttggtgaa attgtctcaa
    14521 ttttgggaat tgcgaccaat aatttgagta aaaaaacgaa aaatgatata atgaacactg
    14581 tactttatat agaaaaaata gataggtaaa aaatgttaga aaacgatatt aaaaaagtcc
    14641 tcgtttcaca cgatgaaatt acagaaacag ctaaaaaact aggtgctcaa ttaactaaag
    14701 actatgcagg aaaaaatcca atcttagttg ggattttaaa aggatctatt ccttttatgg
    14761 ctgaattggt caaacatatt gatacacata ttgaaatgga cttcatgatg gtttctagct
    14821 accatggtgg aacagcaagt agtggtgtta tcaatattaa acaagatgtg actcaagata
    14881 tcaaaggaag acatgttcta tttgtagaag atatcattga tacaggtcaa actttgaaga
    14941 atttgcgaga tatgtttaaa gaaagagaag cagcttctgt taaaattgca accttgttgg
    15001 ataaaccaga aggacgtgtt gtagaaattg aggcagacta tacttgcttt actatcccaa
    15061 atgagtttgt agtaggttat ggtttagact acaaagaaaa ttatcgtaat cttccttata
    15121 ttggagtatt gaaagaggaa gtgtattcaa attagaaaga ataatcttta atgaaaaaac
    15181 aaaataatgg tttaattaaa aatccttttc tatggttatt atttatcttt ttccttgtga
    15241 caggattcca gtatttctat tctgggaata actcaggagg aagtcagcaa atcaactata
    15301 ctgagttggt acaagaaatt accgatggta atgtaaaaga attaacttac caaccaaatg
    15361 gtagtgttat cgaagtttct ggtgtctata aaaatcctaa aacaagtaaa gaaggaacag
    15421 gtattcagtt tttcacgcca tctgttacta aggtagagaa atttaccagc actattcttc
    15481 ctgcagatac taccgtatca gaattgcaaa aacttgctac tgaccataaa gcagaagtaa
    15541 ctgttaagca tgaaagttca agtggtatat ggattaatct actcgtatcc attgtgccat
    15601 ttggaattct attcttcttc ctattctcta tgatgggaaa tatgggagga ggcaatggcc
    15661 gtaatccaat gagttttgga cgtagtaagg ctaaagcagc aaataaagaa gatattaaag
    15721 taagattttc agatgttgct ggagctgagg aagaaaaaca agaactagtt gaagttgttg
    15781 agttcttaaa agatccaaaa cgattcacaa aacttggagc ccgtattcca gcaggtgttc
    15841 ttttggaggg acctccgggg acaggtaaga ctttgcttgc taaggcagtc gctggagaag
    15901 caggtgttcc attctttagt atctcaggtt ctgactttgt agaaatgttt gtcggagttg
    15961 gagctagtcg tgttcgctct ctttttgagg atgccaaaaa agcagcacca gctatcatct
    16021 ttatcgatga aattgatgct gttggacgtc aacgtggagt cggtctcggc ggaggtaatg
    16081 acgaacgtga acaaaccttg aaccaacttt tgattgagat ggatggtttt gagggaaatg
    16141 aagggattat cgtcatcgct gcgacaaacc gttcagatgt acttgatcct gcccttttgc
    16201 gtccaggacg ttttgataga aaagtattgg ttggccgtcc tgatgttaaa ggtcgtgaag
    16261 caatcttgaa agttcacgct aagaacaagc ctttagcaga agatgttgat ttgaaattag
    16321 tggctcaaca aactccaggc tttgttggtg ctgatttaga gaatgtcttg aatgaagcag
    16381 ctttagttgc tgctcgtcgc aataaatcga taattgatgc ttcagatatt gatgaagcag
    16441 aagatagagt tattgctgga ccttctaaga aagataagac agtttcacaa aaagaacgag
    16501 aattggttgc ttaccatgag gcaggacata ccattgttgg tctagtcttg tcgaatgctc
    16561 gcgttgtcca taaggttaca attgtaccac gcggccgtgc aggcggatac atgattgcac
    16621 ttcctaaaga ggatcaaatg cttctatcta aagaagatat gaaagagcaa ttggctggct
    16681 taatgggtgg acgtgtagct gaagaaatta tctttaatgt ccaaactaca ggagcttcaa
    16741 acgactttga acaagcgaca caaatggcac gtgcaatggt tacagagtac ggtatgagtg
    16801 aaaaacttgg cccagtacaa tatgaaggaa accatgctat gcttggtgca cagagtcctc
    16861 aaaaatcaat ttcagaacaa acagcttatg aaattgatga agaggttcgt tcattattaa
    16921 atgaggcacg aaataaagct gctgaaatta ttcagtcaaa tcgtgaaact cacaagttaa
    16981 ttgcagaagc attattgaaa tacgaaacat tggatagtac acaaattaaa gctctttacg
    17041 aaacaggaaa gatgcctgaa gcagtagaag aggaatctca tgcactatcc tatgatgaag
    17101 taaagtcaaa aatgaatgac gaaaaataac cctgagagag gctggagcct ctcttttttg
    17161 tgcagtttag gagctaaagg gaacagaatg gagaaaatgg aacaaatgtg ttttctaatc
    17221 tgttagactg tatctagaaa ggggaaaatt atgattaaag aattgtatga agaagtccaa
    17281 gggactgtgt ataagtgtag aaatgaatat taccttcatt tatgggaatt gtcggattgg
    17341 gagcaagaag gcatgctctg cttacatgaa ttgattagta gagaagaagg actggtagac
    17401 gatattccac gtttaaggaa atatttcaag accaagtttc gaaatcgaat tttagactat
    17461 atccgtaaac aggaaagtca gaagcgtaga tacgataaag aaccctatga agaagtgggt
    17521 gagatcagtc atcgtataag tgaggggggt ctctggctag atgattatta tctctttcat
    17581 gaaacactaa gagattatag aaacaaacaa agtaaagaga aacaagaaga actagaacgc
    17641 gtcttaagca atgaacgatt tcgatggcgt caaagagtat taagagactt acgcattgtg
    17701 tttaaggagt ttactatccg tacccattag taagtcatgc aaaaaaaatg aaaaaaatta
    17761 gaaaaagtag ttgacaaagt ttgaaaaggc tgtataatag taagagttga aaataacaac
    17821 tcaggtccgt tggtcaaggg gttaagacac cgccttttca cggcggtaac acgggttcga
    17881 atcccgtacg gactatggta tgttgcgtca ggagcacttg atgaaaaaaa gtt
//
LOCUS       DAVLHB010000044        15459 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLHB010000044 DAVLHB010000000
VERSION     DAVLHB010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.044"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            737..1264
                     /locus_tag="VXE36_001632"
     CDS             737..1264
                     /locus_tag="VXE36_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779893.1"
                     /translation="MLIVSAIPSVSAVYASEQVSQIETNMELQPVTSLTEEQINTLAN
                     EIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGITVNQMGALLDTAIALA
                     LGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALEFAMNLLSPGTYLAQL
                     WDKNDAIPNNGRINF"
     gene            complement(2309..4567)
                     /gene="glgP"
                     /locus_tag="VXE36_001633"
     CDS             complement(2309..4567)
                     /gene="glgP"
                     /locus_tag="VXE36_001633"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0779894.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(4593..6110)
                     /gene="malQ"
                     /locus_tag="VXE36_001634"
     CDS             complement(4593..6110)
                     /gene="malQ"
                     /locus_tag="VXE36_001634"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0779895.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            6660..7931
                     /locus_tag="VXE36_001635"
     CDS             6660..7931
                     /locus_tag="VXE36_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0779896.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            8042..9334
                     /locus_tag="VXE36_001636"
     CDS             8042..9334
                     /locus_tag="VXE36_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0779897.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            9336..10178
                     /locus_tag="VXE36_001637"
     CDS             9336..10178
                     /locus_tag="VXE36_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0779898.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHSWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            10431..11231
                     /locus_tag="VXE36_001638"
     CDS             10431..11231
                     /locus_tag="VXE36_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0779899.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            11241..12227
                     /locus_tag="VXE36_001639"
     CDS             11241..12227
                     /locus_tag="VXE36_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0779900.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            12363..12443
                     /locus_tag="VXE36_001640"
                     /pseudo
     CDS             12363..12443
                     /locus_tag="VXE36_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12608..13549)
                     /locus_tag="VXE36_001641"
     CDS             complement(12608..13549)
                     /locus_tag="VXE36_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0779901.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(13527..15290)
                     /gene="aspS"
                     /locus_tag="VXE36_001642"
     CDS             complement(13527..15290)
                     /gene="aspS"
                     /locus_tag="VXE36_001642"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0779902.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT         4669 a         3293 c         2894 g         4603 t
ORIGIN      
        1 atctgcaacc tcaaagctgt actttgagca acctacggct agtttactct ttgattttca
       61 ttgagtataa actagacttc gcaaaagtag aaaacttacc gaaaatcttc aatatgacaa
      121 aaacgtataa gaacaggtac acaaacctta atcttatgcg ttttgttata gtttccatac
      181 gcattaaggg gaaatagttg aaatcagttc ttttaataac cattgaatac catatactac
      241 atttacccca aatatgatat aggccgtata aatcaagtat ttcgattttt cccgcctcaa
      301 agaatagatc ttatacaaaa taaataaatt taaaataata aataatagag acaaaatctt
      361 cctccaaaat caatcctaaa agtacacagt caagcatagc tctaatcttt attttcgatt
      421 cgaaattaca aacttatcaa tgaacaataa gtgatataag gtcagtacca aaccccaaaa
      481 gctaccacga aaagagaatt cttgatgatt gagagtaaac aaatcatggt taccaatata
      541 gaggcaggtc aaaataacaa ataaaatcca aaataaatcc gtccatttat attttgaaaa
      601 atattttttt aacataatag catatttttc ttgactataa taacagtata taataaaatg
      661 taagcagata caaataaaaa ggagaaaagc tcatgaacaa attaatgaaa tttatttcgg
      721 ttttttgacg tcaattgtgt taattgtatc agcgattcca agtgtttcag ctgtatacgc
      781 ttctgaacaa gtatcgcaaa ttgaaacaaa tatggaactt caacctgtca cttctctaac
      841 agaagaacaa atcaatacac ttgcaaacga aatccaatct tttcatccag acgtctcaca
      901 acaatggatc aaagaagtaa ttaaccgaca attacaaggc gattatacaa tcccacctac
      961 atactctcca tttagagcag cttggcaagg tattacagtt aatcaaatgg gtgctctatt
     1021 agatactgca atagctttag ccttaggagg aactactgca ggccttgcaa atctaattaa
     1081 agtaaaagga aaacatgcag caaaaagtgc tattcgttca gcaatttcta gatatctagg
     1141 tagttggttt gtaaatgatg ttgctttaga attcgctatg aatttattat caccggggac
     1201 ttatttagca caattatggg ataaaaatga tgccattcct aacaacggaa ggattaactt
     1261 ttaatcatga gatatacaat aaaattaatt gggtataacg tattttcgtt gtttatattc
     1321 tttatcttat caatgttgtt taaagttccc tttaggtggt ggatcagcat tgcaatgacg
     1381 acttcgtcgt acattgtata taattactta aagaaaaaga gagaaaagga atgatcttat
     1441 accagatcat tccttttctg ctttctgtaa atccctcgga gtgtgtttgg cgctttgata
     1501 cgaagtgtca aagctgtata aacgttacta tttccaaaaa agtaacagaa aattcctgct
     1561 ttgtaggact gctttgggtg agtaatagac atgtcgactc accctatctc ctgatggcga
     1621 aaagaattta gcaatgatgc aagttgttct gaactcgaga aaaaacatgc cgaaatcgaa
     1681 gaaaagcgtg cagaacttga agcgaagaag caagaaatgt tgaagcgctt ggataaatag
     1741 aatttagaaa acagaaaaaa ctaaaaagaa tgtagggttt atttccctac attcttaaaa
     1801 taacttagta cataaatgac aatgctgcca ctgccgtcaa tattgcaaaa actattttcc
     1861 aaattttttt attttttcca aaaatcttat caggtaacaa gcttattaca agaaaggtaa
     1921 taaacaacac caatttaagt gtgtatatca taaaaacacc ttctttccta caattatatt
     1981 ataatacttt atgtaagcga atacaagaga tatgaggtaa ccaactacga aaaaatataa
     2041 ggctgaagac agtaaaaacc agcatttaaa gccttcactg tatctaggat ttccctattt
     2101 ttagacaaga ttgacccaaa tccacagcat ttaaaaaagc gaatttcaat cgaaactcgc
     2161 ttttttacaa gatgtattag tataaatttg tatcttatac tcaatgaaaa tcaaagagca
     2221 aactaggaag ctagccgcag gttgctcaaa gcaccgcttt gaggttgcag ataaagctga
     2281 cgtggtttga agagattttc gaagagtatt agttcaagtg ccagatgtct tcgttatact
     2341 gagcgattgt acggtcagat gagaagaatc ctgctttaga aatgttaacg atgactttat
     2401 ccaaccatgc gtcacggtct tcgtagtcag caagcatttg ctctttgact ttgatgtagt
     2461 cttccaaatc aagaagagtc atgaaccagt ctttgttgat caattcattg taaagacgtt
     2521 ccaagcgctc tttgtttcca gctgcaagaa ctgcatcact aacgatgaag tcaaccaatg
     2581 gtttgatagc ttcacgagcg tagaattcgc ttgatttgta agctgctttt gcgtaaaggt
     2641 cgataacagt ttctgaatct tcaccgaaga tgtagatgtt ttcttctcca accaactcag
     2701 cgatttccac gttagcaccg tccatagtac caagtgtcaa agctccgttc aacatgaatt
     2761 tcatgttacc agtacctgaa gcttctttag aagcaagtga gatttgttct gagatatcac
     2821 atgctgggat aaggaaactt gctgcagtaa cgttgtagtt ttcaaccata actacttgca
     2881 agtgtggagc tactgctgga tcgttagcaa taacttctga catgcaaagg attaaatgga
     2941 taatgtcttg agcgattgtg taggctggag ctgctttacc accaaagaag attgtgattg
     3001 gacgagcagg gatgttacca gctttgatgt caaggtattt gtggatcacg tacaaagcgt
     3061 tcatttgttg gcgtttgtac tcatgaagac gtttgatttg gatatcaaag atagaatttg
     3121 aattgatttc cacaccttgg tgttctttca agtgacgagc caatttacgt ttgttgtgag
     3181 ccttgatgct ttccaatttt tctttgacag ctgctttgtc ttcataagac aaaagttttt
     3241 caagctcatc tgcttcatgg tgccaaccat ctccaagaat ctcatctaag tagtgagaca
     3301 atcttgggtt agcatgcata agccaacgac ggaaagtgat accgtttgtt ttgttgttga
     3361 acttttctgg gtaaaggtcg tagaaggctt tcaactcaga atttttcaag atttcagtat
     3421 ggagtgctgc aaccccgtta acactgtatc cgtagtggat atccatgtga gccatgtgaa
     3481 cacgtccgct ctcatcgatg atttgaacag ctggatcttt gtactctgcc ttcacacgac
     3541 ggtccaattc ttcgatgatt ggtaccaagt gaggaaccac ttcttgcaag aattcaagag
     3601 gccatttttc aagcgcttca gcaaggattg tgtggttagt gtaggcagtc atgctacgaa
     3661 caattgagat tgcttcgtca agctcgatac cacgtgcagt taaaagacga atcaattcag
     3721 gaatcaccat tgatgggtga gtatcgttga tttggacaac tgcgtagtca gcaaggtcat
     3781 gcaagttgct tcctttttcg attgcttcgt cgatgatcaa ttgcgcaccg tttgaaacca
     3841 tgaagtattg ttggaagata cggagcaatt caccttgacg gtcactatca tctgggtaaa
     3901 ggaagagagt caagttgcga gcgatatctg tcttgtcaaa gttgatacca tctttaataa
     3961 tagaagaatc aactgaatcc aagtcaaaca aacgcaagcg gtttttagtc gctgtttcat
     4021 aaccagtaac atcaatatcg taaagagttg atgtcaaagt aaagtctgca aatggtactt
     4081 ggtagctacg gcttgagcga accaaccagt tttgctctgt caaccatgca tttggaattg
     4141 tttcttgttg gttgttttta agaacttgtt ggaaaagacc aaagtggtag ttaagaccaa
     4201 caccgtcacc attcaaacca agagtagcaa ttgagtcgat aaagcaggca gccaaacgtc
     4261 ccaaaccacc attaccaaga gatggttcca attcaacttc ttcaacttcg atcaagtctt
     4321 tacctgcagc tgcaagttct tttttaacat cgtcgtaaag accaaggtta atcaagttgt
     4381 ttgacaagag tttaccaatc aagaactcag ctgagatgta gtaaactttt ttcttaccag
     4441 tgttgactgg tttttggctg cttgcaagct tgctgtagtt aagaagagca aggtaaagct
     4501 cttcattgct acattctgca atggttttat tgtaacgatt ttgtacaaat tcttgtagtg
     4561 ataacatgtt tagttgtctc ctgattattg tcttatttct ttaaatctac caaattttca
     4621 ttaattcggc gataaattgt tgtcaagtca agcaaacctt cctcgacagc tggtgtcaat
     4681 tgatcttcag tcatacgcca agaccagttt ccaccaaggg tagatgggaa gttcatacga
     4741 gctgcctcat ccaattctag taaatcttgc atagttgcaa ttgccataaa gctaactgat
     4801 gaaaatactg tacgaagcat agcgtgtacc actgtttcgt attctttacg gttcgtgtaa
     4861 cgagccatgt actcacgagt cgcatcatca atctcattac ggtaccaacc aagaaccgta
     4921 ttgttatcgt gtgttcctgt gtacataact gagttagcag gtgccaagtg tgggctatca
     4981 atgctttcgt cttctgggtt gaaggcaaat tgaagaatct tcattcctgg gaagccagta
     5041 cgttcacgca attcgatcac ttcatctgtc atgaagccaa ggtcttctgc gatgatgttt
     5101 agctcaccaa gttcttcctt aacggctgca aaaagcttgt agcctggacc tttcacccac
     5161 tcaccaggtg ctgctgtatc ggaaccagca gggatttccc agtaagattc gaagccacgg
     5221 aagtggtcga tacgaacgat atcgtagatt ttgaagcttt cacgcaagcg ttcaatccac
     5281 catttgtagc cgtctttgtc cattgcttcc cagtcataga ttgggttacc ccaaagctga
     5341 ccagttacag aaaactcatc tggtgggcat cctgcgatac aagtagcctt accattgaca
     5401 tctgttttga agagatgtgg atttgcccac atatcacttg aatcttccgc tacgtagatt
     5461 ggcatgtccc caacgatttc gatgtggttg tcgttagcgt aagctttcaa tttcaaccat
     5521 tgttggaaga agaagtattg agtcacacgg tggtaaacca acttgtctgc caattgctca
     5581 cgatagcttt caagtgctga agctttacga gcacgagcat ctgcatctgg ccattcagtc
     5641 caagcaagat tgtcaaaata ctctttgata gccatatact cagcaaagag ctcaagccat
     5701 gattggttgt cttgagcaaa tttctcaaaa tctttaacat ctccgacttc aaagaaacgt
     5761 ttcaccgctt tttctaaaag aggacgacgt gcatagtaga ttttagcata gtcaacttca
     5821 gacgcatcgc taccaaagtc aactccttca aggtcacttg cttccaacaa accttgctcc
     5881 accaagatat ctaaatcgat aaaatgagtg tttcctgcga aggctgagaa agattggtaa
     5941 ggagaatccc cgtaactagt tgctcctaat ggaaggattt gccagtaacg ttgttttgta
     6001 cggaccaaga aatcaacgaa gtcgtaagca ctttgaccaa atgatccgat tccgtaagct
     6061 cctggaagag aagagatgtg catcaacaca ccactttgac gttttttcat aatagcacct
     6121 cgtgtgttaa aataatggaa cgttgcgtat tttgcagacg caaacgtttg cgttacttat
     6181 aagtatactc cttttcaagc ataattgcaa gcgtttttaa aaaacttttt tgattatttt
     6241 taaggagact aactcatttt agcaaagata acttaaaact atctaatcct aaagtttgac
     6301 tctcacgaga cagtctacaa agtacaaaac ctccttaggg agcttgaatt tatatgcaac
     6361 aaagcacaaa cgtctataga aaatagatag ggattagaaa cagggaggta gcccctcctg
     6421 atttccctct ttagacagat tccatatatt tttattaaaa atactgtatt cttatctatt
     6481 tcatactttt cttctattaa aatgcaaaat tatgctatca aatcaagctt aaaaattttt
     6541 taaaattttt acaaaaaata cttgcaaccg ttttctattt gtgctatact aagctcataa
     6601 aggaaaacgt ttgcgtttcc ttatcaataa aacttgctat tctttgggag gaatacacta
     6661 tgtcatctaa atttatgaag agcactgcgg tgcttggaac tgctacactt gctagcttgc
     6721 ttttggtagc ttgcggaagc aaaactgctg ataagcctgc tgattctggt tcatctgaag
     6781 tcaaagaact cactgtatat gtagacgagg gatataagag ctatattgaa gaggttgcta
     6841 aagcttatga aaaagaagct ggagtaaaag tcactcttaa aactggtgat gctctaggag
     6901 gtcttgataa actttctctt gacaaccaat ctggtaatgt ccctgatgtt atgatggctc
     6961 catacgaccg tgtaggtagc cttggttctg acggacaact ttcagaagtg aaattgagcg
     7021 atggtgctaa aacagacgac acaactaaat ctcttgtaac agctgctaat ggtaaagttt
     7081 acggtgctcc tgccgttatc gagtcacttg ttatgtacta caacaaagac ttggtgaaag
     7141 atgctccaaa aacatttgct gacttggaaa accttgctaa agatagcaaa tacgcattcg
     7201 ctggtgaaga tggtaaaact actgccttcc tagctgactg gacaaacttc tactatacat
     7261 atggacttct tgccggtaac ggtgcttacg tctttggcca aaacggtaaa gacgctaaag
     7321 acatcggtct tgcaaacgac ggttctatcg caggtatcaa ctacgctaaa tcttggtacg
     7381 aaaaatggcc taaaggtatg caagatacag aaggtgctgg aaacttaatc caaactcaat
     7441 tccaagaagg taaaacagct gctatcatcg acggaccttg gaaagctcaa gcctttaaag
     7501 atgctaaagt aaactacgga gttgcaacta tcccaactct tccaaatgga aaagaatatg
     7561 ctgcattcgg tggtggtaaa gcttgggtca ttcctcaagc cgttaagaac cttgaagctt
     7621 ctcaaaaatt tgtagacttc cttgttgcaa ctgaacaaca aaaagtatta tatgataaga
     7681 ctaacgaaat cccagctaat actgaggctc gttcatacgc tgaaggtaaa aacgatgagt
     7741 tgacaacagc tgttatcaaa cagttcaaga acactcaacc actgccaaac atctctcaaa
     7801 tgtctgcagt ttgggatcca gcgaaaaata tgctctttga tgctgtaagt ggtcaaaaag
     7861 atgctaaaac agctgctaac gatgctgtaa cattgatcaa agaaacaatc aaacaaaaat
     7921 ttggtgaata aaaaatttgt tcaagggggg tggaaatcaa atcccccttt gaatttatca
     7981 atagagacac aaataattta gctttcttat aaaaaagtag tatcctatga aaggagttaa
     8041 tatggaaaag caacaaccta gtaaagcagc cctgctgtct atcattcctg ggttaggaca
     8101 gatttacaat aaacaaaaag ccaaaggttt tatcttcctt ggtgtaacca tcgtatttgt
     8161 cctttacttc ctagcacttg caacccctga attgagcaac ctcatcactc ttggtgacaa
     8221 accaggtcgt gataattccc tctttatgct gattcgtggt gccttccatc taatctttgt
     8281 aatcgtttat gtactctttt atttctcaaa tatcaaagat gcacatacga ttgcaaaacg
     8341 cattaacaat ggaattccag ttccacgcac actcaaagac atgatcaaag ggatttatga
     8401 aaatggcttc ccttacctct tgatcattcc atcttatgtt gccatgacct tcgcgattat
     8461 cttcccagtt atcgtaacct tgatgatcgc ctttaccaac tacgacttcc aacacttgcc
     8521 accaaacaag ttgttggact gggttggttt gaccaacttt acaaacattt ggagcttgag
     8581 taccttccgt tctgcctttg gttctgttct ttcttggact atcatttggg ctttggcagc
     8641 ttctacttta caaatcgtaa ttggtatctt cacagctatc attgccaacc aaccatttat
     8701 caaaggaaaa cgtatctttg gtgttatttt ccttcttcct tgggctgtcc cagccttcat
     8761 cactatcttg acattctcaa acatgtttaa cgatagtgtc ggtgctatca acactcaagt
     8821 attgccaatc ttggctaaat tccttccttt ccttgatgga gctcttattc cttggaaaac
     8881 agacccaact tggactaaga ttgccttgat tatgatgcaa ggttggctcg gattcccata
     8941 catctacgtt ttgactttgg gtatcttgca atctattcct aacgaccttt acgaagcagc
     9001 ttatattgac ggtgccaacg cttggcaaaa attccgcaac atcactttcc caatgatttt
     9061 ggctgttgcg gcacctactt tgattagcca atacaccttc aactttaaca acttctctat
     9121 catgtacctc ttcaatggtg gaggacctgg tagtgtcgga ggtggagctg gttcaaccga
     9181 tatcttgatc tcatggatct accgtttgac aacaggtaca tctcctcaat actcaatggc
     9241 ggcagctgtt accttgatta tctctatcat tgtcatctca atctctatga tcgcattcaa
     9301 gaaactacac gcatttgata tggaggacgt ctaagatgaa taactcaatt aaactcaaac
     9361 gtagactgac tcaaagcctt acttaccttt acctgattgg tctatcaatt gtaattatct
     9421 atccactgtt gattaccatt atgtcagcct ttaaagcagg taacgtctca gcctttaaac
     9481 tagatactaa tatcgacctc aattttgata actttaaagg cctcttcact gaaaccttgt
     9541 acggtacttg gtacctcaac actttgatta tcgccttaat taccatggct gttcaaacaa
     9601 gtatcatcgt acttgctggt tatgcctaca gccgttacaa cttcttggct cgtaaacaaa
     9661 gtttggtctt cttcttgatc atccaaatgg tgccaactat ggccgctttg acagccttct
     9721 tcgttatggc gcttatgttg aacgccctta accacagctg gttcctcatc ttcctctacg
     9781 ttggtggtgg tatcccgatg aatgcttggc tcatgaaagg ctacttcgat acagtgccaa
     9841 tgtctttaga cgaatctgca aaactagacg gtgcaggaca cttccgccgc ttctggcaaa
     9901 ttgttcttcc acttgttcgc ccaatggttg ccgtacaagc tctctgggcc ttcatgggac
     9961 ctttcgggga ctacatcctc tctagtttct tgcttcgtga gaaagaatac tttactgttg
    10021 ccgtaggtct ccaaaccttc gttaacaatg cgaaaaactt gaagattgcc tacttctcag
    10081 caggtgctat cctcatcgcc cttccaatct gtattctctt cttcttccta caaaagaact
    10141 ttgtttcagg acttacaagt ggtggcgaca agggataatt tatccccgcc accctttttc
    10201 attttatact cttcgaaaat ctcttcaaac cacgtcagct ttatctccaa cctcaaagtt
    10261 gtgctttgag caacctgtgg ctagtttgca ctttgatttt cattgattat tagcaattgt
    10321 tactgtaaat aatatccttg tagcaagcaa tttttctcct agacttgaaa taaagcgcat
    10381 ttctctatat aataatactc atatagaaaa caccttttag aaagatacct atgcttccat
    10441 atccattttc ctatttttca agtatttggg ggtttcgtaa gcccctgtcc aaacgtttcg
    10501 agctcaactg gtttcaactt ctctttacca gtatcttcct tatcagcttg tctatggtac
    10561 ccattgctat ccaaaacagc tcccaggaga cctatccgct agaaactttt atcgataatg
    10621 tctatgaacc tctgacaaat gaggttgtcc aggatctctc tgaacatgct acaattgtcg
    10681 atggcacatt aacttatact ggaacagcta gtcaaacccc ttctgttgtg attggtccaa
    10741 gtcaaatcaa ggaattacct aaggacttgc aactgcattt cgatacaaat gagctagtca
    10801 tcagcaagga aagcaaggag ctgacccgca tctcttaccg agccattcag actgagagtt
    10861 tcaaaagcaa agacagcttg acccaagcaa tttctaaaga ctggtaccaa caaaatcgtg
    10921 tctatatcag cctcttccta gttctcggtg cgagcttcct ctttggtttg aatttcttta
    10981 tcgtctctct aggagctagt cttctccttt atatcactaa gaaatcacgc ctcttttcat
    11041 ttagaacctt taaagagtgc tatcacttta tcttgaactg tttaggattg ccgactctga
    11101 ttacacttat tttgggatta tttggccaaa atatgacaac cctgattact gtacaaaata
    11161 ttctttttgt tctgtatctg gtcactatct tttataaaac acatttccgt gatccaaatt
    11221 accataaata ggagattttt atgcccgtta cgattaaaga cgtggccaag gctgctggtg
    11281 tttcgccttc aaccgtaacc cgtgttattc aaaataaatc aaccattagc gacgaaacaa
    11341 aaaaacgcgt tcgcaaagct atgaaggaac tcaactacca cccaaacctc aacgctcgta
    11401 gcttggtaag cagctatact caggttatcg gattagttct tcctgatgac tcagacgcct
    11461 tctaccagaa tcctttcttt ccatcggttc tacgtggcat ctctcaagtc gcatctgaaa
    11521 accactatgc cattcagata gcaacaggga aagatgagaa ggagcgtctc aacgctattt
    11581 cacaaatggt ctacggcaag cgtgtagatg ggctaatttt tctctatgcc caagaagaag
    11641 accctctcgt aaaactcgtc gcagaagaac agttcccctt ccttatctta ggtaaatctc
    11701 tatctccttt catcccactt gtcgacaacg acaatgttca agctggtttt gatgcgactg
    11761 aatatttcat caaaaaaggc tgcaaacgca ttgcctttat cggaggaagt aaaaagctct
    11821 tcgtgaccaa agaccgttta acaggctatg aacaggcgct taaacattac aaacttacca
    11881 ctgacaacaa tcgcatctac tttgccgacg agtttctgga agaaaagggc tataaattta
    11941 gcaagcgatt attcaagcac gatccacaaa ttgatgctat catcacaacc gatagcctcc
    12001 tagctgaagg tgtttgtaac tatattgcca aacaccagct ggatgtccct gttctcagct
    12061 ttgactcggt taatcccaag ctcaacttgg cagcctatgt cgatatcaat agtttagagc
    12121 ttggtcgtgt ttcccttgaa actattctcc agattattaa tgataataaa aacaataaac
    12181 aaatttgtta ccgtcaattg atcgcccaca aaattatcga aaaataagag actgggcaaa
    12241 aagtcgttaa aagcaaaaac gcatactatc aggtattgaa aaaacttgat actatgcgtt
    12301 ttattgtggg aagatttact tccttttcta ctgaaattga gtcttttccc aagatctttt
    12361 tatactcaat gaaaatcaaa gtgcaaacta ggaagctagc cgcaggttgc tcaaaacact
    12421 gttttgaggt tgtagatgaa actgacgaag tcagctcaaa acatggtttt gaggttgcag
    12481 atagaactga cgaagtcagc tcaaaacatg gttttgaggt tgcagataga actgacgaag
    12541 tcagtaacat atatacggca aggtgaagct gacgtggttt gaagagattt tcgaagagta
    12601 ttaatcacta attatctatc tcaacaaatc ttcctagaat atgaacattt tccgagacag
    12661 agacaaagga gcttggatcc acttgtgtca taatctgttt aaattcatta aactctgcac
    12721 gtgtaatgac agtgattaaa actgcctttc tctcgtgatt ataggttcct tctgcatcgt
    12781 ggatcatggt tgctccgcgg tgcaattttt tatggatttt ttcaattacc ttctctggat
    12841 gatttgtcac aatcatggcc tgcatacgct tttgcttagt aaagactgcg tctgtcacac
    12901 ggctagagac aaagatggta atcatagaat aaagagcgta tttccaacca aaggtcaaac
    12961 ctgctatcag catgatagtt ccatttacca agaaagaaat actaccgaca ttcttacccg
    13021 ttttcttgcg aatagtcagg ctgacgatat ccgtcccacc actggagata ttgtttcgaa
    13081 gagcaaaacc aatccccaaa cccataacaa cacccccaaa aagggaattg ataatgggat
    13141 cctccgtcaa ggttgccaca gggacaaact ggataaagaa ggaactcata gataccgtga
    13201 taaaggtaaa gacggtgaac ttatggccaa tctgatacca agctaagacc atcaaaggga
    13261 agttaatggc gtagaagctt agcgaaatcg gaatatgaaa accaaaccag tgattactca
    13321 aggcagagat aatctgtgcc agacctgttg caccactcga atacacatgc cctggttgga
    13381 aaaagaaatt aactgctact gctgataaaa aaccatagac cagagaggcc gaaatcttct
    13441 catcatactt ttctcgagag atactttgta agacacgtaa aatttttatc tgataagcaa
    13501 agcggcgcag ataatagcgc caccgcttaa ttcgttttgt ttgtttcatc ttcttctact
    13561 tgtaagctga gttcctctag ttgtttgaga gcgactgttg atggagcttg tgtcattggg
    13621 tcagttgcct tgttgttctt aggaaaggca atgacttcac ggatattttc ttctccagca
    13681 agcaacatga caaaacggtc aagcccgata gccaaaccac cgtgtggtgg gaaaccatag
    13741 tccatggctt caagaaggaa accaaactgg tcattggctt cttcagctga gaaaccaaga
    13801 gccttgaaca tgcgttcttg aaggtctttt tggttgatac gaaggctacc accaccaagc
    13861 tcataaccgt tcaagacgat atcgtaagca atggcacgaa ccttagccaa atcaccttct
    13921 aattcgtgag cagtctcttc ctgtggaagt gtgaatggat ggtgggcgct catgtagcgg
    13981 ccttcttctt cagaccattc aaacatcggc cagtcaacca cccaaaggaa gttgaactta
    14041 tcattatcaa tcaagccaag ctctttagca atacgtccac gaagggcacc cagtgttgca
    14101 ttagccactt caagcgtatc cgccacaaag agaaccaagt ccttatcttc aagagcaagc
    14161 gctgttgtca attcttcttg gataccagtc aagaacttgg caactggtcc gtttaattct
    14221 ccatcaacca ccttgaccca agcaagacct ttggcaccat actgtttggc tacttccgtc
    14281 atcttgtcga tgtctttacg tgaatagttg tccgcagctc ctttgaccac aatcgctttt
    14341 acagcaagtg cttctgaaaa gactttaaag tctacacctt tgaccacttc tgtcaagtcc
    14401 tgaagcaaca tgtcaaaacg agtatctggc ttgtcagaac cgtaaagagc catagcatca
    14461 tcgtatttca tacgagggaa cggtagcgtt acttcgatgc cttttgtttc cttcatcacg
    14521 cgcgcgatca agccttctgt aatatcttgg atttcttgct cagtaaggaa ggacgtttcc
    14581 aagtcgacct gagtaaattc aggctggcgg tctccacgca agtcctcgtc acggaaacat
    14641 ttaacgattt ggtagtaacg gtcaaaacca gcattcatca agagctgttt cgtgatttgt
    14701 ggactttgag gaagagcgta aaaatgcccc ttattaacac gagacggcac taaataatca
    14761 cgcgcccctt caggcgttga cttagaaagg aatggtgtct ccacgtcgat aaactccaac
    14821 tcatccaagt agttgcggat agagtgggtc accttggcac gaagtttaag attttccaac
    14881 atttctggac gacgaaggtc aaggtaacgg taacgcaaac gtgtatcgtc atttgcctca
    14941 atgccatcct taatctcaaa tggtgttgtc ttagctgtgt taagcacaat aagagctgtc
    15001 acgtttaact caaccgcacc agttggcaac ttatcattgg cttgctcacg cgcagcgacc
    15061 tgaccagtca cctcaataac aaattcgcta cgaaggcttt cagctgttgc cataacctct
    15121 gcagatactt tttcagggtt gataaccaac tgcatgattc cttcacggtc acgaagatcg
    15181 ataaagatca aaccaccaag gtcacgacga cggccaaccc atcctttcaa ggttatttct
    15241 tgtccgatgt gttcctcacg aacacgacca gcatacatac tacgtttcat tatttctctc
    15301 ctcttttatt ctgttactat tttaccataa aagcgcaggc tcttcatgaa aatcatcaga
    15361 aaagtttgcc agtctttaaa agtcaggtga aagccctaaa aattagcgct aatgctcttc
    15421 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgta
//
LOCUS       DAVLHB010000045        15152 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLHB010000045 DAVLHB010000000
VERSION     DAVLHB010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.045"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            62..343
                     /locus_tag="VXE36_001643"
     CDS             62..343
                     /locus_tag="VXE36_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0779903.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            475..1419
                     /gene="manA"
                     /locus_tag="VXE36_001644"
     CDS             475..1419
                     /gene="manA"
                     /locus_tag="VXE36_001644"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0779904.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1459..2794)
                     /locus_tag="VXE36_001645"
                     /pseudo
     CDS             complement(1459..2794)
                     /locus_tag="VXE36_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3000..3745
                     /locus_tag="VXE36_001646"
                     /pseudo
     CDS             3000..3745
                     /locus_tag="VXE36_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(3774..4229)
                     /locus_tag="VXE36_001647"
     CDS             complement(3774..4229)
                     /locus_tag="VXE36_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0779905.1"
                     /translation="MNRREAVEFVNMCMIKNGDKILVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4249..5424)
                     /locus_tag="VXE36_001648"
     CDS             complement(4249..5424)
                     /locus_tag="VXE36_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0779906.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSLVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5483..6328)
                     /locus_tag="VXE36_001649"
     CDS             complement(5483..6328)
                     /locus_tag="VXE36_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0779907.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6453..7010
                     /locus_tag="VXE36_001650"
     CDS             6453..7010
                     /locus_tag="VXE36_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0779908.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7029..7496
                     /locus_tag="VXE36_001651"
     CDS             7029..7496
                     /locus_tag="VXE36_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0779909.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7585..8214
                     /gene="upp"
                     /locus_tag="VXE36_001652"
     CDS             7585..8214
                     /gene="upp"
                     /locus_tag="VXE36_001652"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0779910.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8388..8978
                     /gene="clpP"
                     /locus_tag="VXE36_001653"
     CDS             8388..8978
                     /gene="clpP"
                     /locus_tag="VXE36_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0779911.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9057..9305
                     /locus_tag="VXE36_001654"
     CDS             9057..9305
                     /locus_tag="VXE36_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0779912.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9407..10567
                     /locus_tag="VXE36_001655"
     CDS             9407..10567
                     /locus_tag="VXE36_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0779913.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10835..11704
                     /locus_tag="VXE36_001656"
     CDS             10835..11704
                     /locus_tag="VXE36_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0779914.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11708..12664
                     /locus_tag="VXE36_001657"
     CDS             11708..12664
                     /locus_tag="VXE36_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0779915.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12664..13428
                     /locus_tag="VXE36_001658"
     CDS             12664..13428
                     /locus_tag="VXE36_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779916.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13428..14138
                     /locus_tag="VXE36_001659"
     CDS             13428..14138
                     /locus_tag="VXE36_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779917.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14445..15101
                     /locus_tag="VXE36_001660"
     CDS             14445..15101
                     /locus_tag="VXE36_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0779918.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
BASE COUNT         4638 a         2932 c         3265 g         4317 t
ORIGIN      
        1 actattatat aatgcttttt gattttagta tagtattatc gtagaaaatg gactcggtgc
       61 tatggataca ccggatgaga atggttatgt agcagatgac tatcggatta cttacttaga
      121 ggcccacatc aaggccatgc gagatgccat ttacaaagac ggggttgact tgcttggtta
      181 tacgacatgg ggctgtatcg attcggtttc agctggcaca ggggaaatga ataagcgcta
      241 tggctttatc tatgtagatc gagataatgt aggaaatggg actctcaaac gtagcaagaa
      301 gaagtccttc tattggtaca tgtcatttat agcaatggtg taagcatcga gtagagcaca
      361 tttgtttact atttttataa aatcttctcc ctgctttata agatgtaaaa aagagttcaa
      421 ttcgaactct ttttttgcta taatgagggg agaaaaatca gacaggagat cgacatgtca
      481 gaaccattat ttttacaatc agttatgcaa gaaaaaatct ggggtggagc caagctacgt
      541 gatgagtttg gctacgacat cccaagtgaa aaaatcggag aatattgggc catctcagcc
      601 catccaaatg gagtctctaa agttgccaat ggtcgttacg agggaacaga tcttgctact
      661 ttgtatgcgg aacaccgtga attatttggc aatcgtccag aacctgtatt tccacttttg
      721 accaagatcc tcgatgccaa cgactggctc agtgtccaag ttcacccaga cgatgcttat
      781 ggactcgagc atgaaggcga actcggaaaa acagaatgct ggtacattat cgcagcggat
      841 gaaggttcag agattatcta cggtcacaat gccaagtcaa aagaagaact ccgccagcaa
      901 atcgaggaca agaactggga tgacttgttg accaaagtcc ctgttaaggc tggagatttc
      961 ttctatgtac caagcgggac tatgcacgct atcggggcgg gtatcttaat ccttgaaacc
     1021 cagcagtcta gcgataccac ctatcgcgtc tatgactttg accgcaagga tgacaaaggc
     1081 aacttgcgtg aacttcatct tgaaaaatcc atcgatgtct tgaacattgg tgagccagca
     1141 aatagccgtc ctgtaactgt taaagcagat gatttgcgtt ccactctcct tgtatctaat
     1201 gatttcttcg cagtttacaa gtgggaaatt actggaaaag ttgactttga aaagacagct
     1261 gactacagct tattgagtgt cttagctggt caaggtcagc taactgttga cgggaaaaat
     1321 tatccaattc aaaaagggag acactttatc ctaccaagtg atgttgaagc ttggactctg
     1381 gaagggcaag gtttggaatt gattgttagc catccataaa aagaaagggc ctgagttcac
     1441 tactcaagtc ctttttgatt acataaattg ggcaatgaag accacaatga tgatgattgg
     1501 aatgacgaaa cgaagaaacg aagaaggaag agccagactt ggaacagtcc ttgtttccat
     1561 gctctttcat cgagatggag ttcctccatt gcaagagcct ttttaaagat atagcctgta
     1621 aaaagtgaaa ggtagagagc tccaaatggc atgaggagat tggaagccaa gaagtccata
     1681 gcgtcaaaga agatcttacc aaaaatgtga acatccgcca tgacaccgta agatagggct
     1741 gaaggaatgc caaagacaaa ggtcaaaatt cctaaaataa cactccattt ggcacgtttg
     1801 ctgttatcct ggttggtgat attgcccaca ttgatctcca gcatcacgac agaagaagtg
     1861 acagtcgcaa agaggaaaag gacgtagaaa atggttccaa aaggcatctt gtcaaagagt
     1921 tgaggcaaga cgataaagag caagctcggt cccccttcaa tatccagtct gaagggggac
     1981 cgagcttgga aaatggctag acctgccatg atggatatcg agatattcat ggctacgatg
     2041 gagattcctg actggactag attggttttc ttgtccaagt aagaagcata ggtcagcatg
     2101 actgtaaccc ctagtgagag ggcaaagaaa gattgtccca gagcatagag gggaccagcg
     2161 ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa ccccttccat ggcatttggc
     2221 aaactgggag agcgttcgat gatgacgaca aagatgataa agagcagggg catcatgact
     2281 ttcgaagctc tttcaatccc tttttgaacc ccacgtgata caataaagat atttaataag
     2341 ataaaggctg cttgagctcc tagggcaatg gctggatttg aaatgattga agtaaataac
     2401 tgagcataat cacccgttcc accaagttgg aacaatttcc caaactcaat acctagatag
     2461 actagaatcc atcctccgat aacactgtaa aaagataaga ggataaagag ggcaaaggcg
     2521 ccaatccaac cgataaagtt gtacttgtta ttcttgccca gttttccaaa ggttttgata
     2581 gcggaaacgc cagcactacg gccaagggca aactcagcca gcaggagagg gaaatcgatt
     2641 aaaatagtgg aaatgagaaa gattagtaaa aagcctccac cgccattagc agcagtcatg
     2701 tagggaaact tccaaacggc accaagcccg atggccagcc agcagatgct agaataaaac
     2761 caagtttcga cccccattgt gatttttctg acatagttaa actctgatct cctttttcaa
     2821 aataagaaaa agctacttga gttgtcaaat agccttctgt ttgattgata gacttgacta
     2881 tcctattatg ttttctaagg tctgtcaaga aaaccatttt caagttttca cacctttctc
     2941 aaaaacgctt gactctgacc taaggggagg ggttatacta tcattgtaag gaggaaatca
     3001 tgtaccatat aaaagaagct gcgcagcttt caggtgtctc tgtcaagacc ctgccctgca
     3061 tcactatgac aagataggac tcttggtccc cttaaagtcg gaaaacggct atcgaaccta
     3121 tagtcaagag gatttggaac gccttcaggt cattctttac tacaaatatc taggcttttc
     3181 tttagagaaa atagcagagc tgttaaagga agaaaggaca gatttattgc cccatttaac
     3241 taggcagttg gactatctaa ctcgcgaaag gcaacatctg gataccttga tttccacctt
     3301 gcaaaaaact attcaagaac aaaaaggaga aagaaaaatg accattgagg aaaaattcac
     3361 gggatttagc tatcaagaca atcaaaaata ccaccaagaa gcggtagaga aatatggtca
     3421 agaagtcatg ggacaagcgc tcgaacgcca aaaaggtcac gaagacgagg ctacggccgc
     3481 ctttaaccaa gtctttcaaa ctttggcaca aaatcttcaa gttggtttac ctgcaacagc
     3541 aaccgaaaac caagagcaag cagccaagct cttgcaagct attcgcactt atggatttga
     3601 ctgctctatt gagatattcg gtcatatcgg taaaggttac gtctacaacc cagagtttaa
     3661 ggaaaacatt gacaagtttg gttctggaac agcccagtac acgtcagatg ccattgcggc
     3721 ttacgttcag acaaatgcag aataaatagg ctaggaattt cctagcctat tttttacttc
     3781 aaatcataaa gccagtcgtc accgtttttg tagtaaaaga attcactgag atcttcttct
     3841 agaaacacac gaagcatatc agacatatca tcggttgcaa gttttagatg agaaagattt
     3901 tcaaagtcct cccaccaaac tttcccttcg tctgaagact ggagttcacc agtaaagtgt
     3961 tctgtcttgt aaaaaaggac gacataacga taatccttgt cgtcatacca gtttttaata
     4021 ccacagagtt ggggtttgga aatgatcaga ccagtttctt ctttcacttc acgaatgaca
     4081 gcatcgacaa aggattcgcc acgttcaaca tgaccaccag gaaaagtaat gccaggccag
     4141 tcgggactaa ctcggtcttg gaccaggatc ttatctccgt ttttaatcat acacatgtta
     4201 acaaattcga ctgcctctct tctgttcatt cttcacaacc tttaatcttt aatcataatg
     4261 cagacttccc gccacccagc cggtacagag agcagaagtg atgttaaagc cacccgtgtg
     4321 ggcattgata tccataactt cgcctgcaaa gtggaggcca ggtaccagct tactttcaag
     4381 ggttttagga ttgatttcct tgagactgac tccacccttg gtaacaaagg actttgcaag
     4441 ggacattttt ccagttacag gaattttaag ttctttaatg gactggacaa gttgttctcg
     4501 ttccttttca gtcagctgtt tgactttttc aggatatcct tgtacaaaaa attcggccaa
     4561 gcgttctggt aacaaggttt ttaaagcgtt tttcaaggat ttttcccgat tttcttctag
     4621 aaatgtaacc aagtccttct cagaaagttg aggcaaaaca tcgagtgaga gaacctcccc
     4681 acctttgacc aagctagaca tgcgtagggc agcaggacct gacaaaccaa agtgggtaaa
     4741 gagtaaatca tgagtgatga catgcttacc ataacttagg gtcacatcgt ccagagaaat
     4801 cccttgtaag gctttatgtg gaaaatctgt taataaagga ctttcagcag cctcaagatc
     4861 ggtgatggta tgcttaaaat ggcgagcaat ctcgtgacca aaaccagtcg aaccagtcga
     4921 aggataagac ttaccacctg ttgtgacaat gagtttctca caagtgaagg tttgatccgc
     4981 tgacttaagg acaaactggt catctacttt tttaacagaa acgatttcta tttgagtagc
     5041 aacttgacca cctagttcag tgattttctt ttccaaagct tcgataatag tccgagactt
     5101 gtcactggct ggaaagacgc gtccgtggtc ttcgacctta agtttaacac cattttctgt
     5161 aaaaaagttg atgatgtcat gattatcgaa ctgggagaaa acactgtaaa gaaagcgtcc
     5221 gtttccagga attccagcta gcaggttgtc taagctacca ttgttggtca cattgcaacg
     5281 tcccccacca gtcccagcta atttttttcc aagtttccga tttttttcga tgaggagggt
     5341 tttctgtcca taaaagctac tggaaatcgt agccatcata ccagcaggtc ccccaccgat
     5401 gacaatagta tcaaaatgtt tcatagctct attgtaccac aaaaaaacaa gagatgatgg
     5461 tcacctcttg tcaagaatgc aattaatcaa tttcatagcc catcagcaaa ccgccctctt
     5521 ctgcatagaa actgcagaga ccagaggttg gtagaatttt aatatccgct tgtgggaagg
     5581 tttcacggat tcgctctgag agctgttgac aacatttttc gttattgcgt tgggccatga
     5641 caatacggcc accagcatat ccagctttta ctaactcatc ataggcagct tgaactgatt
     5701 tctttgatcc ccttgctttt tgtagcaatt cgagagtccc agtttcacta gcttttccga
     5761 ccatacgaat gttgagaagg ccaacgaccg taccgataag cttgctcaaa cggccgttct
     5821 tcaccaagtt atcgactttg gctaggacaa agagcaactt agttttttct tgataggcgg
     5881 tgatagcttc aaccacttct tcaaaagaca agccctggtc aatcaagtca ttcaattttt
     5941 ctacgagtag gtcaacttca ccaccagcag ataaactatc aatcacatga atcttagtgt
     6001 caggatggtc ttccagataa atattctttg ctagttgagc actattgtga ctgccagaaa
     6061 gggtacctgt gatggttact aggaaaatgt ttttggcacc ttcaaatgct cgcaaatagt
     6121 catctgggct tggacaagcc gattttgaag cttctgcagt tgcatacatg gtttccatca
     6181 tttggtcaat atcgagactg gcgtcatcaa caaagacctg atcagctact tgaatggtta
     6241 aggggacgct tacaaaggtt gtgttaatag ctggtgttgg cagttgacga taatcacaac
     6301 cagagtcagc aataattttc caagtcatag aaattctcca tctttgtcag ttatacattg
     6361 acaaaggttc tgtctttttt tacaattata tcatgaaaac ccttgaaaca aaagcatcat
     6421 ccgtctgttg tgacaagtag aaagaaaatg ttatgtctga acgtagaatc tctgaaaagt
     6481 ctcttgaaaa tctcagaaaa tcaaaccaag aatccaattt attaaccaga gaagccattg
     6541 aaacagccct cttgcaactc ttggaaaaaa aggagctgac caagattagt atttctgaat
     6601 tggtcaaacg tgcgggtgtt tcgcgtgcgg ccttttatcg caattatgac tccaaagagg
     6661 aaattttaga gagcgtcttt aaacgaactg tccacaatat tatggaacag ctgcatcatt
     6721 acgatttaaa gacagacctt tatttggttt gggttcacct tttccgggag gccagaaagg
     6781 aagctagagt gattcaattg gccttggatt accatctgga aaaaatcttt gtccaagcca
     6841 tgcaggaatt tctagaaaaa taccatggga aatcaaaagg tgtcagctct tatcttcatt
     6901 ccttctggag ctcagccatc gtctctgtcc ttctaaaatg gatcaaggat ggcatgaagg
     6961 taccagctga aaagattgca gatttaggtt taccattttt taaaaaatag agaaaaagga
     7021 gaaaagagat gactgaaaaa agactggcct gggatgagta ttttgcagcc caagccctac
     7081 taattgcgaa tcgttccact tgtaaacgtg ctaaagtggg cgcgattctg gtaaaagata
     7141 ataaggttat ttccactggt tacaatggtt cggtgtcagg gactgagcat tgtattgatc
     7201 acgaatgttt ggtcattgaa ggccactgtg ttcgcaccct tcacgctgag gtcaatgcta
     7261 tccttcaagg tgctgagcgt ggtgttccca aaggctttac agcctatgta acccattttc
     7321 cttgtctcaa ctgtacaaaa caattgcttc aggtcggctg caagcgtgtg gtttatatca
     7381 accagtaccg aatggacgac tacgcccaat acctttatca agaaaaaggg acagaattga
     7441 cccatttacc acttgagaca gtacagacag ctcttaaaga ggctgatcta atgtaaaaat
     7501 tatcaaaaat aaatggttta gaaagatttt taaaccgttt tttggtataa taagaagaat
     7561 aaattgaaag aaggaattcc aaaaatggga aaaattgaag ttattaatca cccactgatt
     7621 caacacaaat tgtcaatctt gcgtcgtaca gatacttcta caaaagcttt tcgtgagcta
     7681 gtagatgaga ttgcaatgtt gatggggtat gaagtacttc gtgatcttcc actagaagat
     7741 gtggaaatcg aaacaccaat tacaaaaaca gttcaaaaac aattggcagg taagaaattg
     7801 gccatcgtcc caatcttgcg tgcaggtatc gggatggttg atggtctctt gagcttggtt
     7861 ccagctgcta aagttggcca catcggtatg taccgtgatg aagaaacact tcaaccagtt
     7921 gaatacttgg tgaaattgcc tgaggacatt gaccaacgtc aaatttttgt agtagaccca
     7981 atgttggcaa caggtggctc agcaatcttg gctgttgatt ctcttaaaaa acgtggcgca
     8041 tcaaatatca aatttgtctg ccttgtatct gctccagagg gtgtaaaagc ccttcaagaa
     8101 gctcatccag atgtagaaat ctttacagca gccttggatg aacgtttgaa cgaacacggt
     8161 tatatcgttc caggtcttgg agatgctgga gaccgcttgt tcggtacaaa ataagatcga
     8221 aaagaagaat gacttggaaa agtatttcca gtcacgaaag gaggttgggt ttttgtttct
     8281 gtctaatgaa agcagagcaa aaatttgacc ttttttgacc aagatattat aatagtctta
     8341 tcttcagtca tttgaccaac aaaattaaaa ctcaaaagga gaaatgaatg attcctgtag
     8401 ttattgaaca aacaagccgt ggagaacgtt cttacgatat ttactcacgt cttctcaaag
     8461 accgcatcat tatgctgaca ggtccggttg aagacaatat ggctaactct gttattgccc
     8521 aactgctttt cttggatgcc caagatagta caaaagatat ttacctttat gtcaatacac
     8581 caggtggttc tgtttcagct ggtttggcaa tcgtagatac catgaacttt atcaaggcag
     8641 atgtccaaac cattgttatg ggaatggctg catctatggg aacagtcatc gcatcaagtg
     8701 gagcaaaagg caaacgtttc atgcttccaa atgctgaata catgattcac caaccaatgg
     8761 gcggtacagg tggtggtacc caacaaactg atatggctat cgctgcagaa cacttgctca
     8821 aaactcgtaa taccttggaa aaaatcttgg ctgaaaattc aggtcagtca atggaaaaag
     8881 tccatgcaga tgcagaacgt gataactgga tgagcgccca ggaaacactt gaatatggct
     8941 ttattgatga aattatggcc aacaattcat tgaactaatg atgatagaag gcaaactcga
     9001 ctgggtttgc tttttttggt ataataggga gagatttttt agaaagagga tttatcatgt
     9061 ttgaaaaagt caatcgctct ggcttgatta tctatcttta ctataatcgt gatgccaaaa
     9121 aactgcagga ttatggagat attacctatc attccaagaa acatcgttac ttacaactct
     9181 atgttccaac tcaagaagtg gagcaattgg tcggacgctt gagcaaggaa aaatttatta
     9241 aaaaagttag ggtttgtcat atccaagagt tggaaacacc ctttgtgggc aatctttatc
     9301 gataggaaaa cgttatcatc gaaaaagttc aaggaaaaca ttgacaattt tctgataatt
     9361 cggtatattc ttaacagact atttaagaaa taaggagaca aaaaagatga agaaaaaatt
     9421 tgccctatcg tttgtggcgc ttgcaagtgt agcacttctt gcagcctgtg gagaagtgaa
     9481 gtctggagca gtcaacactg ctggtaactc agtagaggaa aagacaatta aaatcgggtt
     9541 taactttgaa gaatcaggtt ctttagctgc atacggaaca gctgaacaaa aaggtgccca
     9601 attggctgtt gatgaaatca atgccgcagg tggtatcgat ggaaaacaaa tcgaagtaat
     9661 cgataaagat aataagtctg aaacagctga ggctgcttca gttacaacta accttgtaac
     9721 ccaatctaaa gtatcagcag tcgtaggacc tgcgacatct ggtgcgactg cagctgcggt
     9781 agcgaacgct acaaaagcag gtgttccatt gatctcacca agtgcgactc aagatggatt
     9841 gactaaaggt caagattacc tctttattgg aactttccaa gatagcttcc aaggaaaaat
     9901 tatctcaaac tatgtttctg aaaaattaaa tgctaagaaa gttgttcttt acactgacaa
     9961 tgccagtgac tatgctaaag ggattgccaa atctttccgc gagtcataca agggtgaaat
    10021 cgttgcagat gaaactttcg tagcaggtga cacagacttc caagcagccc ttacaaaaat
    10081 gaaagggaaa gactttgatg ctatcgttgt tcctggttac tataatgagg ctggtaaaat
    10141 tgtaaaccaa gcgcgtggca tgggaattga caaaccaatc gttggtggtg atggattcaa
    10201 cggtgaggag tttgtacaac aagcaactgc tgaaaaagca tcaaacatct actttatctc
    10261 aggcttctca actactgtag aagtttcagc taaagctaaa gccttccttg acgcttaccg
    10321 tgctaagtac aatgaagagc cttcaacatt tgcagccttg gcttatgatt cagttcacct
    10381 tgtagcaaac gcagcaaaag gtgctaaaaa ttcaggtgaa atcaaggata accttgctaa
    10441 aacaaaagat tttgaaggtg taactggtca aacaagcttc gatgcagacc acaacacagt
    10501 caaaactgct tacatgatga ccatgaacaa tggtaaagtt gaagcagcag aagttgtaaa
    10561 accataatag aaaaatgttg aaatagggaa tgagcctttg actcactccc tgtttcgata
    10621 tttaatactc ttcgaaaatc tcttcaaact gcgtcaacgt cgccttggat tatatatgtg
    10681 actgacttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag
    10741 tttcctagtt tgctctttga ttttcattga gtataagaac ctatcaaaaa gtgagggaaa
    10801 accctcggaa ttataaatag aaagagtgaa tcttatgctc caacaactcg taaatggttt
    10861 gattctaggt agtgtttacg cgctgttagc cctaggatat accatggttt acggaattat
    10921 caagctcatc aacttcgccc atggtgatat ttatatgatg ggagccttta tcggttattt
    10981 cttgatcaat tctttccaaa tgaatttctt tgtagcgctt attgtagcta tgctagcgac
    11041 agctattctt ggtgtcgtga ttgagtttct tgcttaccga cctttgcgcc actctactcg
    11101 tattgctgtt ttgattacgg ctattggggt ttctttccta ttggagtatg gaatggtcta
    11161 tctggttggt gccaataccc gtgccttccc tcaagcgatt caaacagttc gatatgattt
    11221 gggaccaatt agcttaacaa atgtgcagtt aatgattttg gccatttcct tgattttgat
    11281 gattttgtta caagtcattg tccaaaagac taagatgggg aaagccatgc gtgcagtatc
    11341 agtagatagc gacgcggcac aattgatggg gatcaatgta aaccgtacga ttagctttac
    11401 cttcgctttg ggttctgctc ttgcgggtgc ggctggtgtt ctgattgctc tttattataa
    11461 ctctcttgag cctttgatgg gggttactcc aggtcttaaa tctttcgttg ccgcagtact
    11521 tggtggtatc ggaattattc ctggtgcggc tcttggtggc tttgtgattg gtctattgga
    11581 aacctttgcg acagcctttg ggatgtcaga tttccgtgat gccattgttt atggaatctt
    11641 gttgttgatc ttgattgtcc gcccagctgg tatccttggt aagaatgtga aagagaaggt
    11701 gtaaacgatg aaggaaaatt taaaagttaa tattctatgg ttactccttt tgttagctgg
    11761 ctatagcttg attagtgtac tggtttcagt cggagtactt aatctattct atgtacagat
    11821 tttacaacaa attggaatta atattatttt ggctgttggt ctcaacttaa tcgttggttt
    11881 ttcaggacaa ttttcacttg gtcatgctgg tttcatggcg attggtgcct atgcagcagc
    11941 tattattggt tctaaatcac caacctacgg tgccttcttt ggagctatgc ttgtaggggc
    12001 tttgctttca ggagcagttg ccttacttgt cggcattcca accttgcgct tgaaggggga
    12061 ctatcttgcg gtagcaactc tgggtgtttc tgaaattatc cgtatcttta tcatcaatgg
    12121 tggaagtctt acaaatggtg cggcaggtat cttagggatt cctaacttta caacttggca
    12181 aatggtttac ttctttgtcg tgattacaac cattgcaacc ttgaacttct tgcgtagccc
    12241 aattggccgt tcaaccctct ctgttcgtga agatgaaatc gctgctgagt cagttggggt
    12301 taatacgact aaaattaaaa tcatcgcttt tgtctttggt gccattactg caagtattgc
    12361 tgggtcactt caggcaggat ttatcgggtc tgttgtaccg aaagattaca ccttcatcaa
    12421 ctcaatcaac gttttgatta ttgttgtatt tggtggactc ggttccatta caggtgcgat
    12481 tgtttcggct attgttctgg gaattttgaa tatgcttctc caagatgttg ctagtgtgcg
    12541 tatgattatt tacgctttgg ccttggtatt ggtaatgatt ttcagaccag gtggactcct
    12601 tggaacgtgg gaactgagcc tatcacgttt ctttaaaaaa tctaagaagg aggaacaaaa
    12661 ctaatggcat tacttgaagt aaaacagtta accaaacatt ttggtggtct aacagctgtt
    12721 ggagatgtga ctcttgaatt gaacgaaggg gaactggttg gattaatcgg tccaaacgga
    12781 gctgggaaaa ccaccctttt caaccttttg accggtgttt atgaaccaag cgagggaaca
    12841 gtaaccctag atggtcacct tttgaatggg aaatcacctt ataagattgc ctctttggga
    12901 cttggacgta ctttccaaaa tatccgtctc tttaaagatt taacagtttt agataatgtt
    12961 ttgattgctt ttggaaacca tcacaaacag catgttttta ctagtttctt acgcttacca
    13021 gctttttaca agagtgaaaa agaattaaag gataaagctt tggaattgtt gaaaatcttt
    13081 gatttagatg gtgatgcaga gactcttgct aaaaatcttt cctacggaca acaacgtcgt
    13141 ttggaaattg ttcgtgccct tgctacggaa cctaaaattc tcttcttaga tgaaccagca
    13201 gcaggtatga acccacagga aacagccgaa ttgactgagt taattcgtcg tatcaaagat
    13261 gaatttaaga ttacaatcat gttgattgaa cacgatatga atctggtcat ggaagtaaca
    13321 gaacgtatct acgtacttga atatggccgt ttaattgctc aaggaactcc agacgaaatt
    13381 aagaccaata aacgcgttat cgaagcttat ctaggaggtg aagcctaatg tctatgttaa
    13441 aagttgaaaa tctttctgtg cattacggta tgatccaagc agtccgtgat gtaagctttg
    13501 aagttaatga aggagaagtt gtttccctta tcggtgccaa cggtgcaggt aagacaacta
    13561 ttcttcgcac cttgtcaggt ttggttcgac caagttcagg aaagattgaa tttttaggtc
    13621 aagaaatcca aaaaatgcca gctcagaaaa tcgtggcagg tggtctttca caagttccag
    13681 aaggacgcca cgtctttcct ggcttgactg ttatggaaaa tcttgaaatg ggagctttct
    13741 taaagaaaaa tcgtgaagaa aatcaagcaa acttgaagaa ggttttctca cgctttcctc
    13801 gtcttgaaga acgtaagaac caagatgcag ctactctttc aggaggggaa caacaaatgc
    13861 ttgccatggg acgcgctctt atgtcaacac caaaacttct tcttttagat gaaccatcaa
    13921 tgggacttgc cccaatcttt atccaagaga tttttgatat cattcaagat attcagaagc
    13981 aaggaacaac cgtcctcttg attgaacaaa atgccaataa agcactcgca atctctgacc
    14041 gaggatatgt actggaaaca gggaaaatcg tcctatcagg aacaggaaaa gaactcgcct
    14101 catcagaaga agtcagaaaa gcatatctag gtggctaaaa caatccagtg gattgtttta
    14161 gtcggcagat gaagattacg aagtaatcat caatatagtc cgggggacct ttttagtcgg
    14221 tagattgaga ttgcaaacaa atctgcatct acattgaaag ctgaatttct aataattgaa
    14281 aaaatcgaat gaaaagtttc ttaccttcat tcacagaact cgatttcaga gctcttttgc
    14341 tagcttattc atacttttct gaatttcgaa aaagaaatgt aagcgtttga tagatttgca
    14401 aaaagattgt ataataggga taagaataga aaaggagaag tctcatggca gttaaagatt
    14461 ttatgacccg caaggtagtt tatattagtc cagatacaac agtatctcat gcagcagatt
    14521 tgatgagaga gcaaggtttg caccgtctgc ctgttatcga aaatgatcaa ttagttggtt
    14581 tggtgactga gggaaccatt gcacaagcaa gtccatctaa agcaacaagt ctttctatct
    14641 atgagatgaa ttatcttctg aataagacaa aagtaaaaga tgtcatgatt cgcgatgttg
    14701 tcactgtctc aggctatgct agtctagaag atgcaactta tctgatgttg aaaaataaga
    14761 ttagtattct ccctgtcgta gataaccatc aagtatacgg agttattact gaccgtgacg
    14821 ttttccaagc ctttcttgaa attgcaggtt atggcgaaga agggattcgt gtacgctttg
    14881 ttacagaaga tgaagttggt gttcttggaa aaattgtttc tttgattgta gaagaaaatt
    14941 tgaatatctc ccatacagtc aatattccgc gtaaggatgg taaggtgatt atcgaagtgc
    15001 aaatcgatgg atcaattgat ttaccagcct tgaaagaaaa atttgaagca aatggtattc
    15061 aagtggaaga aatcgctcgc acttcagcaa aagtcttgta agaagggaag cccaaaggct
    15121 tcttttttca tgaaaagggg attagagaaa aa
//
LOCUS       DAVLHB010000046        14858 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLHB010000046 DAVLHB010000000
VERSION     DAVLHB010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.046"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            644..877
                     /locus_tag="VXE36_001661"
     CDS             644..877
                     /locus_tag="VXE36_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0779919.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            1160..3109
                     /gene="mutL"
                     /locus_tag="VXE36_001662"
     CDS             1160..3109
                     /gene="mutL"
                     /locus_tag="VXE36_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0779920.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3434..3901)
                     /locus_tag="VXE36_001663"
     CDS             complement(3434..3901)
                     /locus_tag="VXE36_001663"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0779921.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3902..5107)
                     /locus_tag="VXE36_001664"
     CDS             complement(3902..5107)
                     /locus_tag="VXE36_001664"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0779922.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRIHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5127..5762)
                     /gene="ribE"
                     /locus_tag="VXE36_001665"
     CDS             complement(5127..5762)
                     /gene="ribE"
                     /locus_tag="VXE36_001665"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0779923.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5747..6847)
                     /gene="ribD"
                     /locus_tag="VXE36_001666"
     CDS             complement(5747..6847)
                     /gene="ribD"
                     /locus_tag="VXE36_001666"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0779924.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(6981..7095)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7252..7845
                     /gene="ruvA"
                     /locus_tag="VXE36_001667"
     CDS             7252..7845
                     /gene="ruvA"
                     /locus_tag="VXE36_001667"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0779925.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7855..8418
                     /locus_tag="VXE36_001668"
     CDS             7855..8418
                     /locus_tag="VXE36_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0779926.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8415..9092
                     /locus_tag="VXE36_001669"
     CDS             8415..9092
                     /locus_tag="VXE36_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0779927.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9247..10278)
                     /locus_tag="VXE36_001670"
     CDS             complement(9247..10278)
                     /locus_tag="VXE36_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0779928.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(10533..11216)
                     /locus_tag="VXE36_001671"
     CDS             complement(10533..11216)
                     /locus_tag="VXE36_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0779929.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11228..12172)
                     /locus_tag="VXE36_001672"
     CDS             complement(11228..12172)
                     /locus_tag="VXE36_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0779930.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            complement(12334..13500)
                     /locus_tag="VXE36_001673"
     CDS             complement(12334..13500)
                     /locus_tag="VXE36_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0779931.1"
                     /translation="MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKELK
                     QKANQEKIAFQKAGSTRQKASTIKNYQELANLWLESYKNTVKPNTQGNVRKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKGAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRQKVKHFENQELKKFLGYLDNLDTHRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHVTKTLNRDIEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRESVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(13733..14698)
                     /locus_tag="VXE36_001674"
     CDS             complement(13733..14698)
                     /locus_tag="VXE36_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEV0779932.1"
                     /translation="MQKPFKTIPEQIELLHKRGLIITDYKRAKKYLLTNNYYSIINGY
                     SKYFEQSPNKYRPGTNFSEITYSYFYDKEIKYSFLKAILEAEKHIKSAIAYVFSERFA
                     STPYFYLDINNYNKSNSDNVRKIKFVIRQMVKIIDKHKSSRQANSIQHYFSKHLEIPF
                     WVIIDYLTFGDMLAILQTLPISLQDKISKKFYSFICEHIKININFTPAILVSFVENIG
                     EVRNVCAHDNRLFSFKCKKSVKYYSDLHSNYGISNSCAKSSPYHVFIVLQCFLSSIEY
                     AKLHNTLLSRFKTFEKHLLTVSIDKFLTELGFPANWHRTMPKLPQ"
BASE COUNT         4285 a         2782 c         2896 g         4895 t
ORIGIN      
        1 tcgttgtacc aacaaatacc tccacatcaa cttcttggta gggtaaatac taccattgat
       61 tctattattt cttttggaat gccaattggt agtttagttg caggaacgct tattgatttg
      121 aatattgaat tagtgttaat tgctattagc ataccttatt ttttgttttc ttatattttt
      181 tatacggata atggattgaa agaatttagt atatattaga aatgtttatg ttcattcaaa
      241 agcataatga ctataactga aaaagaaaag tgatatcttt aaggttgttc ttcttggtgg
      301 tgagattcgt gagacaaccc aagcttttgt cggaaagatt accaatgctt tgatggatag
      361 gatgtacttt agcaagatgt ttttagtggt aacggtatcg tggatggacg tgtaataacc
      421 tcttctttcg aggagtattt tactaaaaaa ctagccttgg agcgttcccc agaaacggac
      481 ttactcattg actcttcaaa gatttgggga gaagattttg cttcatctgt tccttgaaaa
      541 aagtcacagc agtcatcaca gacgatagta ctgaacaaaa ctatgaagag ttagaaattt
      601 atacgcaggt gattgtataa aggatctgga aatagataag aagttgatta gtattgacct
      661 aggtggtaca aatattaaga ttactgttct ttcaaatgac ggtgagattg aaactttgtg
      721 gagtattaca acagatacaa gtgagaaagg ttctcaaatt atatcggaca tcatcagttc
      781 tattaaaaat aaattgaccg aacggaatat tcctgatagc gaccttcttg gaatcggtat
      841 gggaagttgc tcatcatact ttccttgtaa atcatagggg ctataaactc tccgtctact
      901 tgtcctgcaa caattgaagt ctgctcaaaa cgccgtccgc taatcttttc atagactttc
      961 tcccttttag gagcctagct ttctagtttg ttctttgatt tttattgagt ataccactat
     1021 tttactccct ctggcaaggg actttgtcta tgtggaggga ttgggctcct atgtggtgga
     1081 gcttttctgt tctttctgaa atatggtata atagcactaa tcaatttcta ggaaaataga
     1141 tacagaaagg ggctgaaaga tgtctcatat tattgaattg ccagagatgc tggcaaacca
     1201 aatcgcggct ggagaggtca ttgaacgtcc tgccagtgtg gtcaaagagt tggtagaaaa
     1261 tgccattgac gcgggctcta gtcagattat cattgagatt gaggaagctg gtctcaagaa
     1321 ggttcaaatc acggataacg gtcatggaat tgcccacgat gaggtggagt tggccctgcg
     1381 tcgccatgcg accagtaaga taaaaaatca agcagatctc tttcggattc ggacgcttgg
     1441 ttttcgtggt gaagccttgc cttctattgc gtctgttagt gtcttgactc tgttaacggc
     1501 ggtggatggt gctagtcatg gaaccaagtt agtcgcgcgt gggggtgaag ttgaggaagt
     1561 catcccagcg actagtcctg tgggaaccaa ggtttgtgtg gaggatctct ttttcaacac
     1621 gcctgcccgt ctcaagtata tgaagagcca gcaagcggag ttgtctcata tcattgatat
     1681 tgtcaaccgt ctgggcttgg cccatcctga gatttctttt agcttgatta gtgatggcaa
     1741 ggaaatgacg cggacagcag ggactggtca attgcgccaa gcaatcgcag ggatttacgg
     1801 tttggtcagt gccaagaaga tgattgaaat tgagaactct gacctagatt tcgaaatttc
     1861 aggttttgtg tccttgcctg agttgactcg ggctaaccgc aattatatca gcctcttcat
     1921 caatggccgt tatattaaga acttcctgct caatcgtgct attttggatg gttttggaag
     1981 caagcttatg gttggacgtt ttccactggc tgtcattcac atccatatcg acccttatct
     2041 agcggatgtc aatgtgcatc caactaagca agaggtgcgg atttccaagg aaaaagaact
     2101 gatgactctg gtttcagaag ctattgcaaa tagtctcaag gaacaaacct tgattccaga
     2161 tgccttggaa aatcttgcca aatcgaccgt gcgcaatcgt gagaaggtgg agcaaactat
     2221 tctcccactc aaagaaaata cgctctacta tgagaaaact gagccgtcaa gacctagtca
     2281 aactgaagta gctgattatc aggtagaatt gactgatgaa gggcaggatt tgaccctgtt
     2341 tgccaaggaa accttggacc gattgaccaa gccagcaaaa ctgcattttg cagagagaaa
     2401 gcctgctaac tacgaccagc tagaccatcc agagttagat cttgctagca tcgataaggc
     2461 ttatgacaaa ctggagcgag aagaagcatc cagcttccca gagttggagt ttttcggaca
     2521 aatgcacggg acttatctct ttgcccaagg gcgagatgga ctttacatca tagatcagca
     2581 cgctgctcag gaacgggtca agtacgagga gtaccgtgaa agcattggca atgttgacca
     2641 gagccagcag caactcctag tgccctatat ctttgaattt cctgcggatg atgccctgcg
     2701 tctcaaggaa agaatgcctc tcttagagga agtgggcgtc tttctagcag agtacggaga
     2761 aaatcaattt attctacgtg aacatcctat ttggatggca gaagaagaga ttgaatcagg
     2821 catctatgag atgtgcgaca tgctcctttt gaccaaggaa gtttctatca agaaataccg
     2881 agcagagctg gctatcatga tgtcttgcaa gcgatctatc aaggccaatc atcgtattga
     2941 tgatcattca gctagacaac tcctctatca gctttctcaa tgtgacaatc cctataactg
     3001 tcctcacgga cgtcctgttt tggtgcattt taccaagtcg gatatggaaa agatgttccg
     3061 acgtattcag gaaaatcaca ccagtctccg tgagttgggg aaatattaaa agtataaaaa
     3121 agtctgggaa aaattttcaa aatcagaaaa acgcataaaa tcaggtgttc aaaaaccttg
     3181 attttatgcg ttttatcata gaaatattta cttcattttt tcctaattct tttcgaaact
     3241 ctttttaaac gacgtcagtt ttatcagtaa tctcaaaaca gtgttttgag ctaattttgc
     3301 cagttttgtc tgtaacatcg aagttgtgtt tgaccactct gcgactggtt tcctagtttg
     3361 ctctatgatt ttcacagagt attaaattgc gattttgcca agtttcttta ttcgtctaaa
     3421 agtagagtct gttctatgcg tctaatgtac gaattaggtt gaccatttca atagctcctt
     3481 gtgcacactc agaaccctta tttcctgctt tagtaccagc tcgttctatg gcttgttcaa
     3541 ttgtatctgt cgttagcaca ccaaacataa caggaatttc gctatttaaa ctgatttggg
     3601 cgattccctt agatacctcg ctacatacat aatcataatg acttgtattc cctctaatga
     3661 cagctcccaa gcagataatt gcatcatatt ttttactttt tgccattttt gatgcaatca
     3721 gtgatatttc aaaagctcct ggaacccagg ctacctctat atctttctcg tttacattct
     3781 ctcttttgag attatctagt gctccagata ataattttga agttataaat tcattaaatc
     3841 tcgctacaac aatacctatt ttaatattgt ttgctactaa attaccttca taagtgttca
     3901 tttatttttc ctccatattt aaaatgtgac ccattcgatt tttctttgtt tctaaataaa
     3961 aactatcgta aggattggct tctatttcga ttgatattct actggaaata gtaattccat
     4021 atttttctaa ctgttcaacc ttgtcaggat tatttgtcag taaatgaagt gactgaagtc
     4081 ccagatcttt aagcatttgt gctccaatat gatattctct taaatcacct tcaaagccta
     4141 atgcaagatt ggcatcaagc gtatccatgc cttgatcttg taaatgatag gcttttaatt
     4201 tattgataag tccaattcct cgtccctcct gtcgcaagta aagtaagaca cccgaaccat
     4261 tctcaacaat cattttcata gctttatcga attgctgtcc acaatcgcaa cgtaaagagc
     4321 ctaaaacatc ccctgttaaa cattcggagt ggatccgaca taatacattg gcttcatcct
     4381 ctatgtttcc cataataaga gcaagatgat gttccccatt tagtttatct atatagctaa
     4441 ttgctttgaa attaccgtat ctagtaggca tattgacagt tgaaactcgt tctaccagct
     4501 gatcatatac ttttctatat tcttgtaatt ctttgatggt aattagtgga atgttgtgtt
     4561 tcttcgagaa ctgaattaaa tcatctgttc tcatcatttt gccatcatga ttcattattt
     4621 cacaacatag gccacactct tttagtccag ctaattttaa taaatcaaca gttgcttctg
     4681 tgtgtccact tctttctaga acaccacctt tttttgcaat taaaggaaac atgtgtcctg
     4741 gcctgcgaaa atcagagggt gttatatctt cagctacaca catacgtgcg gtcagtcctc
     4801 tttcctcggc agaaatacct gtggtcgttt ctttataatc aattgaaact gtaaaagcag
     4861 tcttatgatt atctgtattg ttttcaacca taggtgaaag cattaattga ttagctaaac
     4921 tttcgctcat aggcatacaa attaatcctt tggcataagt agccataaaa ttaacatttt
     4981 ctgttgtagc tgcttgtgca gaacaaatta agtctccttc attttctcta tccttgtcgt
     5041 ctataacaag aacaagtcgt cccttctgca atgcttctaa tgcttcttgt atttttcgat
     5101 attccattga ctgattatcc tttctgctaa aatccatttt gatataatag ttccttagat
     5161 atttctgatt ttggagagtt atccatcagt ttttgcacat atttacctaa gatatcattt
     5221 tcaagattta ctgtactccc gacttgttta ctcttaagaa tggtttgttc caaggtatga
     5281 gggataacag atactgaaaa gtttactttg gagactttag cgacagtcag actaatgccg
     5341 tcaattgtaa tagatccttt ttcaactatt aaatctaaaa tttctttttg tgtgttgatt
     5401 tgataccata cagcattatc atcttttttt attgacgaga tttttcctgt accatcaatg
     5461 tgtcctgtaa cgacgtgacc cccaagtcga ccgttgacag ataaggctct ttctagattc
     5521 acctcacttc catgttttaa tagagtaaga gctgttcgac tccatgtttc attcattaca
     5581 tcaactgtaa aggattgatg attgaaatga gtaactgtaa gacagatacc atttactgct
     5641 atactatcgc ctaaatggat atccgttaat atttttgagg ctttaattga tagtttacaa
     5701 ttacgagagt ctttctgtat tctttcaact tttccgattt cttcaattat tcctgtgaac
     5761 atggataaat cacttcactt tctatgagat agtcatttcc tatttgagaa aatgcataag
     5821 gtttcaatct aatagcgtca tttggcaaag aaataccttc acctccgaca ggaaacttgg
     5881 cactacctcc aaaaattttt ggtgcaatat atattttcag ctcatcaaca atttgttgtt
     5941 ccaaagcact ccaattcatt agactgcccc cttctagaac taggctatca atctgcatgt
     6001 ttcctagatg ttgcattaaa ctcgataagt ctatatgatt gccttttttc tttatggaaa
     6061 gtatttcaca gccatgattt tgatatagct tcattttatt tttgtcttca gaggaagtgg
     6121 caatgtaagt tttaatatca tttgctgttt ttacgatttt agaggtaaga ggagttcgta
     6181 aatgtgtatc gcatatgata cggataggat ttttcccttc ctccaatcta catgtcagca
     6241 aaggatcgtc ttgaataaca gtattgactc ccaccataat tgcactaaca tggtgtcgta
     6301 actgatgcac atgctttctt gcttcttctt cagtaatcca tttggattga tttgttttag
     6361 tggctatttt tccatccatt gacattgcat atttcataaa aacatagggt acatgctggg
     6421 taatatactt tctaaaactt tttattaagt taagacactc attttctaaa attccaacag
     6481 taacttgaag attattttcc tcaagtatct ttactccttt tccagataca ataggattac
     6541 agtctaggct tccaatgact actcttgtaa taccactatc gattatagca tctatacagg
     6601 gaggtgtttt cccgaagtga caacagggtt caagtgttac ataaagcgtc gctccgacag
     6661 gggattctct acagttttta agagcatttc tctcagcatg tgggccacca aaaaactcat
     6721 gataaccttg tccgataatg tgattatctt ttacaataac tgcgccgacc ataggattgg
     6781 gattgacgta accagcccct ttttgtgcca gttttattgc taatttcata tattttgaat
     6841 cgctcatctc actacctcca aaaaaatatg ccttgaatag gggactactc aaggcataca
     6901 aaagaaaact tatgcgatta acaaaaatgc tctgaaatga caagtaatca tttcagagca
     6961 cgcaaaaagc acaaatatac ttttatcttc tttcatccag actatactgt cggctttgga
     7021 atttcaccaa atcatgcctt tcggctcgtg ggctatacca ccggtaggga atttcaccct
     7081 gccctgaaga tagttattca attacagatg attatagtac ttaattttga atatgtcaac
     7141 agataaatac cgattgtttt tgatatactg tatttgtgat aatcgattct cgctcctcgg
     7201 ataaagaaaa tatgatatac tagataaacg aaataagaga gaaggaatac tatgtacgca
     7261 tatttaaaag gaatcattac caaaattact gccaaataca ttgttcttga aaccaatggt
     7321 attggttata tcctgcatgt ggccaatcct tatgcctatt caggtcaggt taatcaggag
     7381 gctcagattt atgtgcatca ggttgtgcgt gaggacgccc atttgcttta tggatttcgc
     7441 tcagaggatg agaaaaagct ctttcttagt ctgatttcgg tctctgggat tggtcctgta
     7501 tcagctcttg ctattatcgc tgctgatgac aatgctggct tggttcaagc cattgaaacc
     7561 aagaacatca cctacttgac caagttccct aaaattggca agaaaacagc ccagcagatg
     7621 gtgctggact tggaaggcaa ggtagtagtt gcaggagatg accttcctgc caaggtcgca
     7681 gtgcaagcaa gtgctgaaaa ccaagaattg gaagaagcta tggaagccat gttggctctg
     7741 ggctacaagg caacagagct caagaaaatc aagaaattct ttgaaggaac gacagataca
     7801 gctgagaact atatcaagtc ggcccttaaa atgttggtca aataggagca gagaatgaca
     7861 aaacgttgtt cgtgggtcaa gatgaccaac ccgctctaca tcgcctatca tgatgaggag
     7921 tggggccagc ccctccatga tgaccaagta ttgtttgagt tgttgtgtat ggaaacctat
     7981 caggcaggcc tgtcttggga aacggtactc aacaaacgcc aagctttccg agaagtcttt
     8041 catagctatc aaattcactc agtcgcagag atgactgaca ctgaattgga agccatgctg
     8101 gagaatccag ctatcattcg aaatagagcc aagctttttg ctacacgcgc taacgcccaa
     8161 gtctttctac agttacaggc agagtacggc tcttttgatg cctatctttg gtcttttgtt
     8221 gaggggaaaa ctgtcgttaa cgatgttcct gattatcgcc aagcgccagc taaaacaccc
     8281 ttatctgaga aattagccaa agatctcaaa aaacgaggct tcaagttcac aggcccagtc
     8341 gccgtattgt cttttctaca ggctgcaggg ctagttgatg accacgagaa tgattgtgag
     8401 tggaaaggtc ttaaatgatg tctaacaaaa ataagggaat tctgattttt gcgattctct
     8461 atacagtcct ctttgtgttt gatggcgtta aattgctggc ttctttaatg ccatctgtca
     8521 ttgcaaatta tcttgtttat gtagttttag ctttatatgg ctccttcttg ttcaaggata
     8581 gattgatcca acaatggaag gagattagaa agactaaaag aaaattcttc tttggcgtct
     8641 taacaggatg gctctttctc attctgatga ctgttgtctt tgaatttgta tcagagatgt
     8701 tgaagcagtt tgtgagacta gatggacaag gtctaaatca gtctaatatt caaagtacct
     8761 ttcaagaaca accactactg atagctgttt ttgcttgtgt cattggacct ctggtagaag
     8821 aattattttt ccgtcaggtc ttattgcatt acttgcagga acggttgcca ggtttactaa
     8881 gcattattct ggtaggactt gtttttgctt tgactcatat gcacagtttg gctctatcag
     8941 agtggattgg tgcagttggt tacttaggtg gaggccttgc cttttctatt atttatgtga
     9001 aagaaaaaga gaatatctac tatcccctac ttgttcacat gttaagcaac agcctctcct
     9061 taatcatttt agctatcagt atagtaaaat gaaataagaa caggacaaat caatcaggac
     9121 agtcaaatcg atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatac
     9181 actgtaacat gtgatgaaaa tgccagtaat gataccgaga aaaaagctga gaaacttttc
     9241 ccagctttat ttgttatagt caaagcgaat gacttgttcc tgtgcatcta catgagcatg
     9301 gaccccaaag ggtacaattg ctcttggagt tgcgtggccg acattcagat tatagacaat
     9361 cgggatattg ctgtcaatga tatctaatag tgcctcttta tagtcgtcat ggaaagtttc
     9421 atccataggt tttccgacca agagtccatt gatgaccgcg aatatgccag tgtcctttaa
     9481 agttagcaac atctttttga agtcttctgg cttaggcttt tcttcgcttg tttcgagcaa
     9541 gaggattttc ccttcccagt ctgacaagtc agggaaaagt ttgtattttg ggcagagttc
     9601 cgtgctatct gcgtatcgag agttgtcaaa gatatcgtag agggattcta ggcaaccacc
     9661 gaggattttc ccctcgaact gagcacttcc ttgcaacaag tcaaaacctg tatttgtatg
     9721 actgacacga ggtgttccca gggccgtggg actaaaatca gttcgttcct cataccaaac
     9781 gtcactaggg cggatttctg aaattcttcc cgtctcaatc aattctttaa agtagtgaag
     9841 gctataggct agcatttctt tgtctaattc acaaatgtct gctaaaaagg attgaccata
     9901 aaaagtcttg attcctaatt tatgcaacat gaggtggttc atggttgtat ccgagaagcc
     9961 aagaaaaatt ttttgcttga taaccttttg gagttggtca ttttcaaaaa gataaggtag
    10021 caagcgatag gtatcgtctc caccgatggc acataggatc atgtcgatgc tatcatcaga
    10081 aaaggcatga atcaaatcct ctgcacgagc ttcaggatgg tccttgataa agtctaatcc
    10141 ttttaacgaa tggggcaaaa agatgggatt gagtcccaga tccttgagac gttggatacc
    10201 caagtccact tcgtgtttga caaaatcctc tccgataatg ccactagata aactaacaat
    10261 accaatagta gaaaccatat ctcatcctcc tagaaataga ttgagcctat tttatcacaa
    10321 aatataagag aaagctatgt gggatttcag aagaatactt ttaatactct tcgaaaatct
    10381 cttcaaacca cgtcagtttt atctgcaacc tcaaagctgt gctttgagca acctgcagct
    10441 agcttcctag tttgctcttt gattttcatt gaatataact caaaaaagta agtgaaaaag
    10501 caaccgcacc tgcagttgct tttatcgttt tcttattctt gatagcgtgt tggtcctgca
    10561 cttgcactac ggatattcaa gcgtttcttg agatagaagc gaagggctag gagggctgct
    10621 ccaataatag ctagtggcaa tggatccagt actgggttaa ggctagctgg taggaagctt
    10681 gttgcaaaga agacaagcaa ccaaaggaac atagaagcta ggataactag tacagatttc
    10741 cagaaaggtg gacgttgact gcgatccata tctggtccat agtattggta aacaaagtag
    10801 tacatcaagt agaaggcaaa tccaccaacc agtccaacta atagaagagt aatcaatcca
    10861 tagccgaaag cttggtctgc cgcaaagaag gttgtgaggg cgctgacaag ggcaaagagg
    10921 ctagtgatga aaagagctga gtccataatc atcagttttg ggtcatcatt ttcttttgga
    10981 tgctcttttt cgtactgctc tttgacagtg aagctatgag cccaatgagt tggtgcgccg
    11041 tatagggaac gggcagttgt acctttagat tgctcctcaa ggatttgggg aatgacttcc
    11101 tcaaaaatag tctggatttc agcgtctgtt ttcccatctt tgatgaattg ttgggtagca
    11161 atgtggacaa actcttggtt tttcttagtt aatttttgta gatcaatttg agacatagga
    11221 actcctctta gaaccatttt ttatggatga gatagagagt gagcgagaca ctcatagcaa
    11281 aggcgataaa gacgattaac cagaaggcat ttggctctcc gtttaggggg atttcattat
    11341 ccttaaagtt catcccgtag gcagaaaaga ccatggttgg gatggacatg acgatggtca
    11401 caagggccaa ggttttcatg atgttgttct ggttgttaga aatgatagag gcaaaggtct
    11461 ctgtcataga atgcaagacg tttccataaa tatctgccat ctcgatggcc tgttgggttt
    11521 caatcagggt gtcttcaagc aggtcttcgt cctcaaggta tttcttgata ttgctggttg
    11581 aactggtcaa tttcttaatc acgcgctcat ttgttttgag ggaggccttg aaatagacga
    11641 tagttttttc caattccatg agctcaatca attcttcatt acgagttgat tgatgcagtt
    11701 gactttcgat ttgttcactc ttgcggtcga ttgaacgaag ggctgttagg taaagctctg
    11761 cattgcgata aagaatttga aagataaaac gtgaacgcat gaaggtatag aaattacgca
    11821 atcgacggtt gataaagaca tcaaggacag gtagtggttc caaacacgta gtgataatgg
    11881 tttcctcagt gatgataata ccaagcggga tggttacgta gtaggtgcgg ttatttcttt
    11941 cctccgtgac cggcacgtct acgataatca gggtatactc gtcttcaatg gtaatacgag
    12001 acatttcttc cgcatcgagc ggtgctcgaa ggtcggcaat atcaatatcg aaggtgttgg
    12061 cgatttcgag tgattcattt tgagtcggat tgacgagatt gatccaagta cccggttcaa
    12121 gcgtatcgat ctctttaaat tcagttgttg tagagagaaa aacttgtttc atatccctta
    12181 tcctttctca tttttcagat tttttcacac tgtactatta tactacaaaa tcggcctttt
    12241 tcaaaataaa tctaacaaaa atcctgttgc tattggattt ttactttgtc ttgaaatgtt
    12301 gatttttaaa tttgctcccc tttttgctcc cccctatagt gcttttagtg cagtttcgta
    12361 gaatgatact gctttttttg cgttctcttt tgagaggtgg ctatatatat ccatggtcat
    12421 tgataaagtg gaatgaccta ggcggtactg gagttccttg tatggtattc cagagttaag
    12481 caataaacta gcgtgagtat gacggaatcc gtgaaagcca atgttaggaa catcagcacg
    12541 cttaaaatgt gtttgcaatc ttcttttaag tcttgaactg ctaggatact catgaatgaa
    12601 atcagaaaat actacacttt cacgttgccc tatcttccag gcctctttag tttggcgcag
    12661 tttgtactgc tttagcatgc taacagtcgc ttgatctata tctatatccc gataactagc
    12721 cttagatttt gggctattga tttctatatc ccgatttagt gttttggtaa catgtaccac
    12781 ggcattatct aaatctatat cagaccagga aagagctaaa gcttcattga tacggcaacc
    12841 agtagccaat aggaacttat agagcgttgt ctcatagtaa taacggtatc tatgagtatc
    12901 taaattatcg agataaccaa gaaacttttt tagttcttga ttttcaaagt gttttacctt
    12961 ttggcgcttt gctttctgag tgttacgagg taaaacaaca tcacgcgcag gattggacgg
    13021 tatagcttgc atggttacgc catactgtaa gatacgtttg tttaaagcgt gtatcttgtc
    13081 ataatgtaga aaagcccctt tttcccctct attagtctta tcagcaagtt cgttgataat
    13141 ggactggata agtggagtag tgagcttatc gagcttgtaa gccccaaaaa taggcaatat
    13201 atgattatcg attagctttc tgacatttcc ttgagtgttt ggcttaactg tattcttata
    13261 actttctaac cagagattgg ctaattcttg atagtttttt atggtgctag ccttttgtct
    13321 agtagatcct gctttttgaa aagctatttt ttcttgattg gctttctgtt ttaattcctt
    13381 ttgtgtccga cctgttacct tggttttgac tttctttcct gttacctggt caactcctag
    13441 atatacatta gcacgataga ctttactacc gtcttttttt ataacttcag ttattttcat
    13501 gatgataaac ctttctaaaa tacatcagca ggcaagccat tatcaaaaag gttttatatc
    13561 atgctagggc ttcatagttt gccctgtatt cgattttaag tagtcagacg gtaaataata
    13621 ccagaggagg gaacaaggcg gatatggcta gtattatcta aagttttaaa ttcctgttca
    13681 taaaattaat agttaagttc cataatttca ttaaattgta tagttttact aactattgtg
    13741 gtaacttggg cattgttcta tgccagtttg caggaaatcc taattcagtt aaaaacttat
    13801 caattgagac tgtaagtaga tgtttttcaa atgttttaaa tcttgatagt aatgtattat
    13861 gtaacttagc atactcaatt gaacttaaaa agcattgtaa gactataaaa acatggtaag
    13921 ggctactttt tgcacaagaa ttactaatac catagttaga atgtaaatct gaatagtatt
    13981 taacactttt cttacactta aagctaaaaa gtctattatc atgagcgcat acatttctaa
    14041 cttctccaat attctctaca aaactaacaa gtatagctgg tgtgaaattt atattaattt
    14101 taatatgctc acaaataaaa ctataaaact tttttgaaat tttatcttgt aaagaaattg
    14161 ggagagtttg taaaattgct aacatatctc cgaaagtcag ataatcaatt attacccaaa
    14221 atggtatttc aagatgttta ctaaaataat gttgaatact attcgcttgt ctacttgact
    14281 tatgtttatc tattatttta accatttgac ggatcacaaa tttaatcttt cgaacattat
    14341 cactattcga cttattatag ttatttatat ctaagtaaaa ataaggtgta gaagcaaatc
    14401 tttcagaaaa tacatatgca attgctgatt ttatatgttt ttctgcttcc aatattgctt
    14461 ttaaaaaaga atattttatc tctttgtcat aaaaataact gtaagtgatt tctgaaaagt
    14521 ttgttccagg tctatattta tttggtgact gttcaaaata tttactgtac ccattgataa
    14581 tactgtagta attgttagtt aatagatatt tttttgctct tttataatct gtaattatta
    14641 ggccacgttt atgaagcaat tctatttgtt ctggaatagt tttaaatggt ttttgcaaaa
    14701 aaaagcacct ccatatagaa ggtgctattt tcgcgttccc gtttcactga gaataatcgg
    14761 gcgctaattc cttaagtacc ttcattgtat gataatttta aatgttagtc aacagttttg
    14821 ttcaaaataa ttgatttttc tttacttcgt tttgtttg
//
LOCUS       DAVLHB010000047        14376 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLHB010000047 DAVLHB010000000
VERSION     DAVLHB010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14376
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.047"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(45..788)
                     /gene="srtA"
                     /locus_tag="VXE36_001675"
     CDS             complement(45..788)
                     /gene="srtA"
                     /locus_tag="VXE36_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0779933.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            complement(788..3256)
                     /gene="gyrA"
                     /locus_tag="VXE36_001676"
     CDS             complement(788..3256)
                     /gene="gyrA"
                     /locus_tag="VXE36_001676"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0779934.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            3450..4436
                     /locus_tag="VXE36_001677"
     CDS             3450..4436
                     /locus_tag="VXE36_001677"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0779935.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            complement(4684..5457)
                     /locus_tag="VXE36_001678"
     CDS             complement(4684..5457)
                     /locus_tag="VXE36_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEV0779936.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5504..5758)
                     /locus_tag="VXE36_001679"
     CDS             complement(5504..5758)
                     /locus_tag="VXE36_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0779937.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKIITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            complement(5760..6002)
                     /locus_tag="VXE36_001680"
     CDS             complement(5760..6002)
                     /locus_tag="VXE36_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0779938.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLQDE"
     gene            complement(6093..6902)
                     /locus_tag="VXE36_001681"
     CDS             complement(6093..6902)
                     /locus_tag="VXE36_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0779939.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            complement(6904..8253)
                     /gene="vicK"
                     /locus_tag="VXE36_001682"
     CDS             complement(6904..8253)
                     /gene="vicK"
                     /locus_tag="VXE36_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0779940.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            complement(8246..8950)
                     /locus_tag="VXE36_001683"
     CDS             complement(8246..8950)
                     /locus_tag="VXE36_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0779941.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            complement(9005..10180)
                     /gene="mutY"
                     /locus_tag="VXE36_001684"
     CDS             complement(9005..10180)
                     /gene="mutY"
                     /locus_tag="VXE36_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0779942.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            complement(10508..12178)
                     /locus_tag="VXE36_001685"
     CDS             complement(10508..12178)
                     /locus_tag="VXE36_001685"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0779943.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVAVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            12408..13097
                     /gene="coaB"
                     /locus_tag="VXE36_001686"
     CDS             12408..13097
                     /gene="coaB"
                     /locus_tag="VXE36_001686"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0779944.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            13109..13660
                     /gene="coaC"
                     /locus_tag="VXE36_001687"
     CDS             13109..13660
                     /gene="coaC"
                     /locus_tag="VXE36_001687"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0779945.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            13644..14207
                     /locus_tag="VXE36_001688"
     CDS             13644..14207
                     /locus_tag="VXE36_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0779946.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
BASE COUNT         4296 a         3202 c         2488 g         4390 t
ORIGIN      
        1 aaatcttaaa aaatcagtga aatccatgat ttcactgatt tgtattaata aaattgttta
       61 tatggttgat tgaaagctgt taggatttca tcagatgttt gtgaataatc ttttgtttct
      121 ttcaaatcac ctttgacaat aatacgttct gtagcagcaa ggtcttcaca ggttactaat
      181 gtgatttcat tgaccccatc tctatcatca acttcatcaa cacgatccgg tgtcacacgt
      241 ttgacttcac gtatttcata agtataaact ttatttttat cggttagata aatcttcatg
      301 ccatttttag cattatctaa aggagaaaat aacattttat tagcattatc aacaccaaag
      361 atatggtgac tagctagact ataatttcct tctcccatta cttgctcgcg tttcattgta
      421 ccagctccgt agaagagatt aacattatca agtcctttaa aaatcggcaa attcatttcc
      481 aattcaggaa ttgcaattcc cccaataact ggtaattttt gagcatccca ttgagaagtt
      541 agaacagctt ccgaagagat agctttgaca gaatcaaagt caaaattgcc ttctgtatcc
      601 tgattttctt ctaatttttc ttttgatacc tggctaactt gatacttatt ggtattccag
      661 actatgaaaa tatttcgaat ttgagtatta aaaatcaaag ccagtgacag taatatcaga
      721 aatcctgcta ggatatttgt cagcagattt tttcgcttgt ttttcttttt attatttttt
      781 tgagacatta tgcttcacct tctgtttcgt tttctgtccc aacttcttct ttttctgcca
      841 ccgcaaccgt tgtgaaagtc actatctgag catcttgatc caggcgcatt actttaactc
      901 ccatagttgc acgtcctgtt tgtgaaatat tggcaagatt ggttcgaatc atgacacctg
      961 tatcagtgat aatcatcaaa tcctcatccc cttgaacagt cataagaccg gccagcaagc
     1021 catttttttc ggtaatttta gctgtctgca ttcccttacc accacgacct tttgttgggt
     1081 attcagtagc gactgtacgc ttaccatatc ctttttctgt gataataaga acctcatctt
     1141 gatcagtaat caagctggca ccaacaactg tgtctccttc acgaaggtta acacctttca
     1201 caccagtggc gatacggctc ataccacgaa cggctgattg attaaagcga actgcataac
     1261 caaacttggt accaatgata atatccatat ctccttctgc caacaagaca ttgattaact
     1321 catcttcatc ctttaaattc agcgctttga gaccattttg acgaatattg gcaaactcct
     1381 taacactggt tctcttcaca ataccgtgac gggttgtaaa gaagagataa gcatcatcac
     1441 tgcgatcaga ctcaacattg ataaccgtct gaatactttc gtcttcatcc aatttcaaga
     1501 gattgactac tggtagccct ttggcagtcc gaccatactc aggaatttca taacctttaa
     1561 gacgatagac acgtcccttg tttgtgaaga agagcagatg atcatgggta ctagttgaca
     1621 ctaactcacg aacaaagtca tcatctttca ctcccgttcc ttggacacca cgacccccac
     1681 gtttttgagc agtgaactcg tcctgatcca aacgcttaat gtagcctctg ttagaaaggg
     1741 taatcaagac atccgattct tcaatcaagt cctcatcctc gagactcaag acctgtccaa
     1801 ccatcaactc tgtacggcgt ttatcagaaa atttacgttt aacttcatcc aattcgtctt
     1861 tgataatttg agaaacacgt tcaggcttag caagaatatc tgctaaatcc gcaatcagag
     1921 ccaagaggtc atcatactca gattgaatct tatcgcgttc caaacctgtc aaacgacgaa
     1981 gacgcatatc aaggatagct tgactttgac gttcagaaag cttaaacttg ctcatcaact
     2041 cagcttgagc ttccgcatcc gtttcactag cacggatgat acgaatcact tcgtcgatat
     2101 ggtctagcgc aatcaagaga ccttctaaga tatgagcgcg cgcttccgct ttttccttat
     2161 caaaacgtgt acgacgaaca accacttctt tttggtgctc gatataagca tccaaaatct
     2221 gacgaagaga caaaattttc ggtataccat tttggatagc gagcatattg aaaccaaaat
     2281 tggtttgcat ttgggtcatt ttgaagaggt tattgagaat aacattggct gaggcgtcgc
     2341 gcttgacttc aataacaaat cgaacacctt cacggtttga ctcatcacgt actgctgtga
     2401 taccctcaat gcgtttttcc tgaaccaagc gaacaatatg ctcatgcacc ttggttttat
     2461 tgaccatgta aggaaattct gttacaacga tgcgctcacg accagtctta gtcgtttcaa
     2521 tctctgtacg agaacgtagg acaatcgaac ctttacctgt ttcataagcc ttatggatac
     2581 ctgatttccc catgacaaga gcaccagttg gaaaatctgg tccaggcaag acttccatca
     2641 agtccttggt agtcacttca ggattatcca tgaccaactt cactgcatca atggtttcac
     2701 ccagattatg aggtggaata ttggttgcca tcccaaccgc gataccagtt gctccattaa
     2761 ccaaaaggtt tggaaaacgc gctggcaaga ccaagggttc ccgttcattg gcatcatagt
     2821 tatcaacgaa atcaactgta tttttgttga tatcacgaag catttccaga gcaatcttgc
     2881 tcatacgtgc ctcggtataa cgttgagcgg cagcactatc tccatccatg gaaccaaaat
     2941 tcccatgacc atctacaagc atgtaacggt agctccacca ttgagccata cggaccatgg
     3001 cttcataaat agaggaatcc ccgtgtgggt gatatttacc catgacatcc cctgtaatac
     3061 gagcagattt tttatggggt ttgtctgggg tcacacccaa ttcattcatt ccgtagagaa
     3121 tgcgacggtg aacaggtttt aagccatctc gaacatcagg aagagctcgc gctacgataa
     3181 cactcatggc gtagtcgata aaacttgcct tcatctcctt tgtcagattg acattcacta
     3241 aatttttatc ctgcattaat aaatgcctca tttcacaatt agtaagtaac aacattatac
     3301 cataaattcc catctatttc agcctctaaa ccactaaaac gtttacatcg agaactataa
     3361 ggcatattcg tgacaaagtt ttttaaaagt gatagaatga agttgtctag ggaaaatccc
     3421 ctaataaaat taaggagatg tttaaaacaa tgacttcaac taaacaacac aaaaaagtta
     3481 tccttgtcgg tgatggtgct gtaggttcat cttacgcttt tgcacttgtt aaccaaggaa
     3541 ttgcacaaga gcttggaatt atcgaaattc cacaattgca tgaaaaagct gttggtgatg
     3601 cgcttgacct tagtcacgcc cttgccttca cttcacctaa aaaaatctat gcagctcaat
     3661 actctgactg tgcagacgct gaccttgttg tgatcactgc aggtgcacct caaaaaccag
     3721 gtgaaactcg tcttgacctt gtaggtaaaa accttgctat caacaaatca atcgtaactc
     3781 aagttgttga atctggtttc aaaggtatct tccttgttgc tgctaatcca gttgacgttt
     3841 tgacttactc aacttggaaa ttctctggtt tccctaaaga acgcgttatc ggttcaggta
     3901 cttcacttga ctcagctcgt ttccgtcaag cacttgctga aaaattggat gtggatgctc
     3961 gttcagtgca cgcctacatc atgggtgaac acggtgactc tgagttcgct gtttggtcac
     4021 acgctaacat cgctggtgta aaccttgaag aattccttaa agacactcaa aatgttcaag
     4081 aagctgaatt gattgaattg ttcgaaggtg ttcgtgatgc agcctacaca atcatcaaca
     4141 aaaaaggtgc aacatactac ggtatcgcag tagcccttgc tcgtatcact aaagcaatcc
     4201 ttgacgatga aaacgcagta cttccacttt cagtattcca agaaggtcaa tacggagttg
     4261 agaatgtctt tatcggtcaa ccagctgttg ttggtgcaca tggtatcgtt cgtccagtaa
     4321 acattccatt gaacgatgca gaaactcaaa aaatgcaagc atctgctaaa gaattgcaag
     4381 ctattattga cgaagcatgg aaaaatccag aattccaaga agcttctaaa aactaattta
     4441 actatagaca actccttgaa tcatcaggga gttgtttttt cctgtattat gagaaatagt
     4501 acctcgttac tctaaaacgt tgttataaaa tgctttaaat tcctaattga tttgttcaga
     4561 ttttatttta tttctctata aaacgcatag tatcaagttt ttatacctga taatatgcgt
     4621 tctattgtgt caaaacttac ttgatttctc ctcagttcaa actttttctc atctttattt
     4681 ttattatgtt ttttcaatca aatcttgtat cattttatgt agttcttcta tctttttaga
     4741 ttgtttctct agtaatattc tctgactaga taattcatct tggagtttat caagttttat
     4801 ctgttcatct ggattatcct ttacaaaaaa gttcgtcaaa gcacttgtta acatccctat
     4861 tgttccaata ccgacaagca tcagtaaaac tgctagccat ttcccaaaaa tggaagcagg
     4921 aacaatatcc ccatatccaa cagtcgttac cgttacaaga gcccaccaaa gactatctga
     4981 gaaggatttt tcttcaacta cagataaaat tgaacttcct actagcacga taaagatatt
     5041 aacatacaag atataaatca agccatttgt ccgtaagaat ctactaattt ttctttctaa
     5101 tttacctgta agtccaatta ttctaagtaa acgagtcagt ttcagtaatt ttgttagttt
     5161 aactaaacga aagatacgcc ctaatcgaaa cactgtaaaa atagcattta aagggagaat
     5221 agccaataaa tcaaaaatat tttcaagaat aaagcgccat tttcttttag taataaaaaa
     5281 gcgccaacta taatcaatta caaaaacacc ccagattact aaatcaataa tactataagg
     5341 cggattgtcc aaatcagtca tctcagcaaa tccaagtaat accagaataa cagagattaa
     5401 agcaagtaaa ataattgttg tgtcataata atctgcaaaa aaccattttt tcttcaaatt
     5461 tttactctcc ttactttcta tactgttatt actcagcttt aattcaataa atatctctcc
     5521 gatgaccaac ttctagagta gcaacgacta attcatcatc tacaatttgt acgataactc
     5581 gataattacc aattctatag cgccattgac caacgcgatt accaaccaaa gcctttccgt
     5641 gtcgtcttgg gtcttccaaa acattggttt gtaaatagtt tgtaattatc ttctgcgtat
     5701 aacggtccaa ttttttcaat tgcttgataa aacgtcttgt tggaactaat ttatacaaat
     5761 tattcatcct gcaagcctaa atcatgcatc atttcttccc aagtaatggg ttcaactcct
     5821 ttttccaagt cttctaaata ctcttgatag gctaaatctg ccacacgagc atcgtattca
     5881 tcttctaggg cttcaagagt tttggtgcga ataagttccg aaagggaaac tccttcaaac
     5941 ttagccattg ctttcataaa tgttttatca gcttcagaaa cttttaatgt aatagtagtc
     6001 atcttttgtg ctcccttttt taatggtaac accattgtat tactttttat gtgttcagtc
     6061 aatataaaaa gaacaccttc tcagcgttct ttctatatct ctgtcaatgg tgttgcggta
     6121 tctggtgagg tatcataaac cttaaagtct actccgactc ccagatcagc ttgagccagc
     6181 tgattgacca tggtcatatg agccagttcc ttgatattat tttccttaga taaatgccca
     6241 aggtaaatct tcttagtacg atttcctagc gtccgaatca tagcttcagc accgtcctcg
     6301 ttagaaaggt gaccaaggtc agataggatt cgttgtttga gtcgccaagc gtaagaacct
     6361 gatcgcaaaa tctctacatc atggttggcc tcgataagat agccatccgc attttcgaca
     6421 atgcccgcca tacggtcact gacataacct gtatctgtca aaaggacaaa actcttatca
     6481 tccttcataa agcgatagaa ctgcggtgcg actgcatcat ggcttacacc aaaactctcg
     6541 atgtcgatat ctccaaaggt tttggtttta cccatttcaa aaatatgctt ttgcgaagaa
     6601 tccaccttgc caagatattt actattttcc atagcttgcc aggtcttttc attggcataa
     6661 agatccatac catacttgcg agccaaaacg cctactccat ggatatgatc tgaatgctca
     6721 tgggtaatca agatggcatc caggtcttct ggcttacggt taatttcagc tagcagactg
     6781 gtaattttct tgccagacaa gcctgcatct actaaaagct tcttttttga ggtttccaga
     6841 taaaaagaat ttccactgga acccgacgct aaaatactgt atttaaagcc tatttcactc
     6901 attctagtct tctacttcat cctcccatac ttcttctttc actgcatcct tatcataagg
     6961 gagcacaatg gtaaaggttg aacccttgcc gtattcactc ttggcccaaa taaagccctt
     7021 atgttgtttg ataatttctt tagcgataga cagtcctaga cctgtaccac cttgtgcacg
     7081 acttctagca cgatccacac gatagaaacg gtcaaagata cgtggtaaat cctgcttagg
     7141 aatccccaaa ccgtggtcag aaatggataa aatcatctgg tcttcagttg tcttcattct
     7201 gacagtgatt ttacccccat ctggcgaata cttaatagca ttatttaaaa tattgtcgac
     7261 aacctgcgtc atcttatctg tatcaatttc catccagata gaattgatgg gataatctct
     7321 caccaactca tattttttct ccttttcctg tcctttcatc ttgtcaaaac gattgaggat
     7381 aaaggtaata aaagcagtga agttaatcag ttccacatct aggtgactgg tagcattatc
     7441 aatacgtgaa agatggagga gatccgtcac catgcgcatc atacggttgg tctcatcaag
     7501 agaaaccttg ataaagtctg gtgctacagt ttcacacaaa gccccctcat ccaaggcttc
     7561 aagataggat tttacgctag tcagaggagt ccgtaactca tggctaacat tggaaacaaa
     7621 gagtcttcgt tcgcgttctt ccttctcctg ctccgtcgta tcatgcaaaa cagccaccaa
     7681 acctgaaata aagccagact ctcgacgtat caaggcaaag cgaactcgaa ggttcaaata
     7741 ttcaccattg atatcttggg aatctagcaa caattctgga ctttgggtaa tcaaatcacg
     7801 caattcatag ttttcttcta tcttgagcaa ttccaaaatg cttctattca gaacatcttc
     7861 cttaaccaac cccagttgct tcttggctgt atcgttaatc atgataatct gaccccgacg
     7921 gttagtcgca agaaccccat ctgtcatata aaacagaata ctatttagcc tcttactctc
     7981 ttgttctaga ttttcctgag tgagacgaat aacctccgac aagtcattca aattattggt
     8041 aatattggtg atttcagacc caccttgcat atcaagaacc ttggaataat ctcctgcaat
     8101 caaatcttta accttttgat tgatttgctt caactgaata ttatcacgtc tattttccag
     8161 taataagagg gtcacaacaa ggatgaaacc taacaaaatc aggataaaga taaaatctct
     8221 ggtaaaaatg gtttgtttca gtaaatcaag cattatttct catgtaatac cctacaccac
     8281 ggcgcgtcaa gatatactct ggtcggctgg gcgtatcttc aatcttctca cgcagacgtc
     8341 gtacagtcac atcaactgtg cggacatcac caaaatagtc ataaccccag acagtctcaa
     8401 gcaagtgttc gcgcgtgatg acttgacctg tatgcgatgc taaatgatac aaaagctcaa
     8461 attcacgatg ggttaagtct agttcttcgc catatttttt agccacgtag gcgtctggaa
     8521 caatttctaa atccccaatt tggataggtt gaggtttact atctgcttcc tgaccatcta
     8581 ctggcatagg ttgagaacga cgcagaagag ctttaacacg cgcctgcaac tcacgattgg
     8641 agaagggttt cgttacatag tcatctgccc caagttccaa accgataacc ttatcaaatt
     8701 cactatcttt ggctgaaagc ataagaatgg gcacactgct tgtcttacga atggtcttag
     8761 caacttctaa accatcaatt tctggaagca tcaaatccag aataataata tctggttgct
     8821 ctgcttcaaa ttgctctagc gcttcacgac cattaaaagc agttacaact tcgtaacctt
     8881 ccttggtcat attaaacttg ataatatccg agattggttt ctcatcatct acaattagta
     8941 tttttttcat atgttcacct ttttctctac tattatacca aaaaatagtc agaagacaca
     9001 atagctagtc ttggctactg tctaagttgg cttgtgcata agcctgccag attttttgtt
     9061 ggggtttggc aagtgggtaa ttcttgaatt cttctggtga aagccaacga acttccctat
     9121 ctgaaaaatc atggaagtca ctcacctgac ctgctacaat ctgtacatgc cattttcgat
     9181 gactaaaaac atgctggact gtatcaaaac aaacatcaag ccaatcaaca tctaggtcat
     9241 agtcctgctg gaaactctct tctggactgg ggccaaagtt cacactttct tccgcaacct
     9301 gatgaaagag gtcaaactgc tcttcttgcg aaaagttatc aacttctata aaggggaaat
     9361 gccaaaaacc tgccaagagc ttttcgcttt catttttttc aagtaaaaat tgtccttgag
     9421 aatttttcac aactaaggct ttaagataaa taggaaccgg ctttttctta ggagatttaa
     9481 ttggataacg gtccatggtt ccattctgat atgccgcact aaagtccttg actgggcttt
     9541 cttcaggtct gggatttaca ggagactcaa tatcagaccc taagtccatc aaggcttgat
     9601 taaaatcacc cggacgatcc ggattaatca agatctccat cattgcctga aaaatttttc
     9661 gattacttgg aatcccaata tcgtggttga cttcaaacag acgcgccaag acccgcatga
     9721 cattaccatc tacagctggc tcaggcaagt taaaagcaat actggaaatg gctcctgctg
     9781 tgtaaggtcc aatccctttc aagctggaaa ttccttcata ggtatttgga aattggccac
     9841 caaagtcagt cataatctgc tgggctgcag cctgcatatt gcgaactcga gaataatagc
     9901 ccaagccctc ccaagctttc agtaaactct cctcaggcgc agttgccaga ctttcgacag
     9961 ttggaaacca gtccaggaat ctttcgtagt aagggataac tgtatccacc ctggtctgct
    10021 gaagcataat ttcagatacc cagatgtgat aaggattttt acttctcctc caaggcaaat
    10081 ctcttttgtt ttcatcatac caagcgagaa gtttctcacg gaaagaaatg actttctcct
    10141 ccggccacat gacgataccg tattctttca aatctaacat atctctagta taacacagaa
    10201 ggtttcacct gtctttgtat ctgatttata atattttcaa tagatagtat ataacttttc
    10261 tatctactta tactcaatga aaatcaaaga gcaaactagg aagctagccg caagttgctc
    10321 aaaacactgt tttgaggttg tggatagaac tgacagagtc agtatcatat acctacggca
    10381 aggtgaagct gacgtagttt gaagagattt tcgaagagta taaatcttat tgatgaactg
    10441 cttgcagtct gagaaaaaat gagcttggat attatttcca aactcactta aagtcaattt
    10501 caatccacta gaacaagcct agtacagttc catcgctttc aacatccatg ttgagagctg
    10561 ctggacgttt tggaagacct ggcatggtca taacatcacc agttaaggca acgatgaagc
    10621 ctgcacctaa ttttggtacc aattcacgaa tggtaatttc aaagttttct ggtgctccaa
    10681 gcgcatttgg attgtctgag aaactgtatt gagttttagc catacagatt ggcaatttgt
    10741 cccaaccgtt ttgaacgatt tgagcaattt gtgtttgagc tttcttctca aagttcactt
    10801 tgctaccacg atagatttca gtgacaattt tttcaatctt ttcttggaca gaaagggcat
    10861 tatcgtacaa acgtttatag ttagctggat tttcagcaat tgtcttaaca actgtttcgg
    10921 caagtgctac tccaccttct gctccatcag cccagacact agccaattca actggtacat
    10981 cgattgaggc acagagttct tttaagactg caatttcagc ttctgtatca gatacaaatt
    11041 cgttaatagc tacaactgct ggaataccga acttacggat attttcaacg tggcgtttca
    11101 agttagcaaa acctgcacga actgcctcta cattttcttc agtcagagcg tctttagcca
    11161 caccaccatt catcttaagg gcacgaaggg ttgcgacaat aacaactgca tctggagatg
    11221 ttggcaagtt tggtgtcttg atatcaagga atttctcagc accaagatcc gcaccaaaac
    11281 cagcttcagt aacagtgtaa tcagccaagt gaagggctgt tgtcgtcgcc aaaacagagt
    11341 tacagccatg agcgatattg gcaaatggac caccgtgtac aaaggcaggt gtaccgtaaa
    11401 ttgtctgaac caagtttggc ttaatagcat ccttcaaaat caaagccaag gcaccctcaa
    11461 cctgcaaatc acctacagca acaggcgtac ggtcatagcg ataaccaata acgatattcg
    11521 ccaaacgacg tttcaagtcc tcgatgtccg ttgccaagca aagaattgcc atgatttctg
    11581 aagcaactgt aatatcaaaa ccgtcctcac gtggaatacc gtttagagga ccaccaagac
    11641 caacagtcac atggcggagc gcacggtcgt tcaagtccac aacgcgtttc cagaggatac
    11701 gacgttgatc aattcccagc tcattccctt ggtgcaagtg gttgtcaatc aaggcagaaa
    11761 gggcattgtt ggcagttgta atagcatgca tatctccagt aaagtggagg ttgatgtctt
    11821 ccattggcag aacttgtgca tacccaccac cagcagcacc acccttgatc cccatgactg
    11881 gaccaagaga cggttcgcgg atagcaatca tggttttctt gccaatcttg ttcaaggcat
    11941 ccgcaagacc aatggtaagc gtcgactttc cttcacctgc aggtgttggg ttgatggcag
    12001 taaccaagat caatttaccg actggattgc tctcaactgc acgaatttta tcaaagctga
    12061 gtttagcctt gtactttccg tacaactcca aatcgtcgta agaaatacca agtttctcta
    12121 caacatcaac aattggcttc aactcaatac tctgtgcgat ttcaatatct gttttcattc
    12181 aaaattcctc taacctctta tatgataatt cattatatca caaaacaaga tttttaacat
    12241 cctaaaactc tctaaacgtt cgtaaatatc tctgttttta aggcttttag agtcctttct
    12301 taaattttat atggctttat agtttgaaac tatagtaaat cttcgttttt accaaaaatt
    12361 tatcactttc attttactta ccgcttattt ttgtgtacaa tagtgctatg aaaattttag
    12421 ttacatcggg cggtaccagt gaagctatcg atagcgtccg ctctatcact aaccattcta
    12481 caggtcactt ggggaaaatt atcacagaga ctttgctttc tgcagggcat gaagtttgtt
    12541 taattacgac aaaacgagct ctgaagccag agcctcatcc taacctaagt attcgagaaa
    12601 ttaccaatac caaggacctt ctaatagaaa tgcaagaacg tgttcaggat tatcaggtct
    12661 tgatccactc aatggctgtt tctgactaca ctcctgttta tatgacaggg cttgaggaag
    12721 ttcaggctag ctccaatcta aaagaatttt taagcaagca gaatcatcag gccaagattt
    12781 cttcaactga tgaggttcag gttttgttcc ttaaaaagac acccaaaatc atatccctag
    12841 tcaaggaatg gaatcctact attcatctga ttggtttcaa actgctggtt gatgttaccg
    12901 aagatcatct ggttgacatt gcacgaaaaa gtcttatcaa gaatcaagca gatttaatca
    12961 tcgcgaatga cctgactcaa atttcagcag gtcagcaccg agctatattt gttgagaaaa
    13021 atcagcttca aacagtccag actaaagaag aaattgcaga actcctcctt gaaaaaattc
    13081 aagcctatca ttcttagaaa ggaaaactat ggcaaacatt ctcttggctg taacgggttc
    13141 aatcgcctct tataagtcgg cagatttagt cagttctcta aaaaaacaag gccatcaagt
    13201 cactgtctta atgactcagg ctgctacaga gtttatccaa cctttgacac tacaggtact
    13261 ctcacagaat cctgtccact tggatgtcat gaaggaaccc tatcctgatc aggtcaatca
    13321 tatcgaactt ggaaaaaaag cagatttatt tatcgtggta cctgcaactg ctaacactat
    13381 tgcaaaacta gctcacggat ttgcggacaa catggtaacc agtacagctc tagccctacc
    13441 aagtcatatt cccaaactaa tagctcctgc tatgaataca aaaatgtatg accatccagt
    13501 aactcagaat aatctgaaaa cattagaaac ctacggctat cagctgattg ctcctaagga
    13561 atctctacta gcttgtggag accacggacg aggagcttta gctgacctca caattatttt
    13621 agaaagaata aaggaaacta tcgatgaaaa aacgctctaa tattgcaccc attgctatct
    13681 tttttgctac catgctcgtg atacactttc tgagctcact tatctttaac ctttttccat
    13741 ttccaatcaa accgaccatt gttcatattc ctgtcattat tgccagcatt atttatggtc
    13801 cacgagttgg ggttacactt ggatttttga tgggattact tagcttgacg gttaacacga
    13861 ttacgattct accgacaagc tacctcttct ctcccttcgt accaaacgga aatatctact
    13921 cagctatcat tgccatcgtc ccacgtattt tgattggttt aactccttac ttagtctata
    13981 aactgatgaa aaacaagact ggtctgattt tagctggagc ccttggttcc ttgacaaata
    14041 ctatctttgt ccttggagga atcttcttcc tatttggaaa tgtttataat ggaaatatcc
    14101 aacttcttct ggcaaccgtt atctcaacaa attcaattgc tgaattggtc atttctgcaa
    14161 ttctaaccct agccattgtt ccacgactac aaaccttgaa aaaataaaaa caatctccgc
    14221 tttcaaacct gaaggtggag attttgctct atacagtttc tttttaatga aatctttact
    14281 atagtaaaac gaaataagaa caggacaaat cgatcaggac agtcaaatcg atttctaaca
    14341 atgttttaga agtagaggtg tactattcta gtttca
//
LOCUS       DAVLHB010000048        14114 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLHB010000048 DAVLHB010000000
VERSION     DAVLHB010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.048"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            81..878
                     /locus_tag="VXE36_001689"
     CDS             81..878
                     /locus_tag="VXE36_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0779947.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VXE36_001690"
     CDS             1026..1148
                     /locus_tag="VXE36_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV0779948.1"
                     /translation="MTRDFKFETLQLHAGQVEAPATKSRAVPIYQTTFFVFDDT"
     gene            1170..1715
                     /locus_tag="VXE36_001691"
     CDS             1170..1715
                     /locus_tag="VXE36_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0779949.1"
                     /translation="MRKPGNIYTRITNPTTAVLEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFP"
     gene            1746..2285
                     /locus_tag="VXE36_001692"
     CDS             1746..2285
                     /locus_tag="VXE36_001692"
                     /inference="COORDINATES: protein motif:HMM:NF013237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0779950.1"
                     /translation="MSYTHDVGAAAFIIAVRVQLLRDTGAALSPFNAFLLLQRLETLS
                     LRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYYALAEKYLPKGVGSIFTFHVKG
                     DEEEARKVIDNLEIFSDLANAADAKSLVVHPATITHGQLSEKDLEAAGVTPNQIHLSI
                     GLENVEDLIEDLRLALEKI"
     gene            2381..3655
                     /locus_tag="VXE36_001693"
     CDS             2381..3655
                     /locus_tag="VXE36_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0779951.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VXE36_001694"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VXE36_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0779952.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYVAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEDATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VXE36_001695"
     CDS             4784..5086
                     /locus_tag="VXE36_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0779953.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VXE36_001696"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VXE36_001696"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0779954.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VXE36_001697"
     CDS             5960..7300
                     /locus_tag="VXE36_001697"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0779955.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VXE36_001698"
     CDS             7278..7490
                     /locus_tag="VXE36_001698"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0779956.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VXE36_001699"
     CDS             7487..8362
                     /locus_tag="VXE36_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0779957.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VXE36_001700"
     CDS             8355..9170
                     /locus_tag="VXE36_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0779958.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VXE36_001701"
     CDS             9163..9594
                     /locus_tag="VXE36_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0779959.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VXE36_001702"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VXE36_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0779960.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VXE36_001703"
     CDS             11270..11998
                     /locus_tag="VXE36_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0779961.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VXE36_001704"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VXE36_001704"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0779962.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         4172 a         2582 c         3360 g         4000 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atgatttctt cagaatttat ctcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgac acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc
     1021 accttatgac tcgtgatttt aaatttgaaa ctctacaact acatgctggt caagttgagg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gtccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgcttgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatattgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaactc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaacacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gacggcttca gggaaattcc cttaatttgt tgacgagagt ccaagctgcc
     1741 acaatttgag ctatactcat gatgtgggtg cagcagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac cctttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttattatgc cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc
     2041 acgtcaaagg tgacgaggag gaagcacgca aggtcattga taatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca atcactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaatcaa atccacttgt
     2221 ctatcggtct tgaaaatgta gaagatttga ttgaagactt acgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggtt ttgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttacaga agtctagaaa gaggaatgta atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga aagccagtat gctgaacttt tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aggcaggaac tggccttggc
     2521 tgagcaaaag gctatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaagt
     2641 tgaacagaca agccatcagg ccttattggc taaggacaag gaagtacagg ccttggaaaa
     2701 ccagttggcg accttgcgtt tggagcatga aaatcaattg caaaagaccc tttctgacct
     2761 agaaaaagaa cgcaatcagg tcaaaaatca gctcctcttg caagaaaagg aaaatgagtt
     2821 gtctttggct tctgttaagc aaaactacga agcccagctt aaagcagcta gtgaacaagt
     2881 cgagttttat aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaatg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gccgataatg actactttaa
     3241 cacagggatt gttgacgtca gccacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccag ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagacttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac
     3541 atctgaaaac caactccgtc tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ttgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggcggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aatcactctg ggctattcca cgacgactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgtggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga tgctcttacc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagatgctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg tagatactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa cttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aaacggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaaaacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgcatt attcgtcgta tcaagcgtga tatggaggag
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccatga aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ttatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc taccccaatt
     6361 ttctaagaga attggggtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggatgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca
     6781 ggaaaaacgg atggcaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccattgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aatccttgca ggttgccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagatcaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagag attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg tctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgacaccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 ttcgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagaaaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attgccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gagacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgaaccatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gatctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagcc atgaatgaca tggaaagtgt cgaagagtat
    10381 gaccctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctcatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaatgaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaagtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagcatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acggtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc ttaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcggcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atctttgttc acgcaggtat
    11701 tgatttgacc ttggatgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacaggaga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccatgg aaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggagct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccatttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 atacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttatccagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taagaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tactgtatgt
    14041 atggttactg acttcgtcag tttcatctac aacctcaaaa ctgtgttttg agtaacctgc
    14101 ggctagcttc ctag
//
LOCUS       DAVLHB010000049        14080 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLHB010000049 DAVLHB010000000
VERSION     DAVLHB010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14080
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.049"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            1..976
                     /locus_tag="VXE36_001705"
                     /pseudo
     CDS             1..976
                     /locus_tag="VXE36_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1061..2263)
                     /gene="rpsA"
                     /locus_tag="VXE36_001706"
     CDS             complement(1061..2263)
                     /gene="rpsA"
                     /locus_tag="VXE36_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0779963.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2425..2496)
                     /locus_tag="VXE36_001707"
     tRNA            complement(2425..2496)
                     /locus_tag="VXE36_001707"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2462..2464),aa:Gln,seq:ttg)
     gene            complement(2506..2586)
                     /locus_tag="VXE36_001708"
     tRNA            complement(2506..2586)
                     /locus_tag="VXE36_001708"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2550..2552),aa:Tyr,seq:gta)
     gene            complement(2636..2866)
                     /locus_tag="VXE36_001709"
     CDS             complement(2636..2866)
                     /locus_tag="VXE36_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0779964.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3034..3678)
                     /gene="pcp"
                     /locus_tag="VXE36_001710"
     CDS             complement(3034..3678)
                     /gene="pcp"
                     /locus_tag="VXE36_001710"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0779965.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIETIVDYKDKDLQLVGGETH"
     gene            complement(3693..4616)
                     /locus_tag="VXE36_001711"
     CDS             complement(3693..4616)
                     /locus_tag="VXE36_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0779966.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4613..5302)
                     /locus_tag="VXE36_001712"
     CDS             complement(4613..5302)
                     /locus_tag="VXE36_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0779967.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5367..6071)
                     /locus_tag="VXE36_001713"
     CDS             complement(5367..6071)
                     /locus_tag="VXE36_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0779968.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTIKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(6127..7149)
                     /locus_tag="VXE36_001714"
     CDS             complement(6127..7149)
                     /locus_tag="VXE36_001714"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0779969.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7281..9752)
                     /gene="parC"
                     /locus_tag="VXE36_001715"
     CDS             complement(7281..9752)
                     /gene="parC"
                     /locus_tag="VXE36_001715"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0779970.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDVAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10172..12115)
                     /gene="parE"
                     /locus_tag="VXE36_001716"
     CDS             complement(10172..12115)
                     /gene="parE"
                     /locus_tag="VXE36_001716"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0779971.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLADKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12251..12892
                     /gene="plsY"
                     /locus_tag="VXE36_001717"
     CDS             12251..12892
                     /gene="plsY"
                     /locus_tag="VXE36_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0779972.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12935..14080)
                     /locus_tag="VXE36_001718"
                     /pseudo
     CDS             complement(12935..14080)
                     /locus_tag="VXE36_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4019 a         3160 c         2478 g         4423 t
ORIGIN      
        1 atttctatga ctgatattgc ccatcagctt tccatctcaa cttcaactgt cattcgcaag
       61 ctcaatgatt ctcactttga gcatgatttt tcgcgtcttc ctgagattat gtcctgggac
      121 gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc ttcattgcgc
      181 aagattttaa caatctcaat atcatcactg ttcttgaggg aagaacacaa gctatcattc
      241 gaaatcactt tcttcgctac gatagagctg tccgatgtcg cgtcaaaatt attactatgg
      301 atatgtttag cccttactat gacttggcta aacagcttcg ctttcaaatt tctaggctca
      361 ggctgaaaca gtctcccaga ctgtttcact cccgaatgct aaaatcgttc ttgatcgctt
      421 tcacattgtg caacatctta gccgtgctat gagtcgtgtg cgtgttcaaa tcatgaatca
      481 gtttcatcga aaatcccatg aatacaaggc tatcaagcgc tactggaagc tcatacaaca
      541 ggatagccgt aaactgagtg ataagcgatt ttatcgtcct acttttcgta tgcatttaac
      601 caataaagag attttagaca agcttttgag ctattcagaa gacttgaaac accactatca
      661 gctctatcag ctcttgctgt ttcacttcca gaataaggaa ccagagaaat ttttcggact
      721 tattgaggac aatcttaagc aggctcatcc tatttttcag actgtcttta aaaccttcct
      781 caaagataaa gaaaagatta tcaacgccct tcaactacac tattctaatg ccaaactgga
      841 agcgaccaat aatctcatca aacttatcaa gcgcaatgcc tttggttttc gaaactttga
      901 aaacttcaaa aaacggattt ttatcgcttt gaacatcaaa aaagaaagga cgaaatttgt
      961 cctttctcaa gcttagctga cttcaaccca ctacagttga caaagagcca gaaaaatccc
     1021 ttgtttagta aacaaaggat tttgtgaatt ttcaatttga ttaaagttcg atatcaccaa
     1081 acaaatcagc cattgaaaat cctgtttgtg tttctggaag ttcgaaatca cgcttttctt
     1141 gacgtcttgg acgacgtgga cgagcagcac gtttttcttc tttttgtcct tcttcttggg
     1201 ctggacgttc ttcaagagct ttaatagaaa gtgacacgcg ttctgcatct gcgttaactt
     1261 caagaacttt aacttgaact tcttgaccaa ctttaagagc ttcttttgga ttttcaatcc
     1321 gtttgtgtga aatttgtgat acgtgaacaa gtccatcgat acctggcaat acttcaacaa
     1381 atgcaccgaa gtcagtcaaa cgtttaactg ttccttctac tacatcacct ttagccaatt
     1441 tttgctcaac gccatcccat ggtcctggta ctgttgcttt aagtgaaagt gatacacgtc
     1501 cttcttcttc gttaagatca aggattttca cttcaatttc ttcaccaaca gttacaactg
     1561 attttggtga tacgttacgt tcatgtgaca attcagtcaa gtgaaccaat ccgtcaacac
     1621 caccaaggtc gatgaaagcg ccgaagcttg tgatacgagc aactttacca gttacaacat
     1681 caccaacagc caatttaccg aatacttcag cgcgagctgc tgcagtagct gcttcaacaa
     1741 cttcacgacg tgaaaggatg aagcggtttt ctttagcgtt aacttctttg attttagtat
     1801 caaattcttg acctacaaaa cgctcagcgt tacgtacgaa acgagtatcc aacattgaag
     1861 ctgggataaa tccacgaaca ccttcaaatt ctactgaaag tccaccttta acggcacgcg
     1921 ttcctttaac agtaacaact tcttcttcgc gaccaacaag tttgtcccat gctttgcgag
     1981 cttcaaggcg ttttttagat acaaggtatg taactgtatc agtatcttta ccaactactt
     2041 gacgaagtac aagaacatcc aatacttctc ctactttaac aaagtcattg atatctgcat
     2101 cacgatcgtt tgtcaattcg cgaagagtca agacaccttc aacaccagtt ccagagattg
     2161 caacgttagc ttgagtcgca tcaactgtca atacttcagc actaacaaca tcaccagtct
     2221 caacttgact aacgctattt agcaaatctt caaattcgtt catctaaaaa atcctccaac
     2281 aatcaagttt ttcttaaact tgacatactt ataatttttt tcctaagcac ccgcaaggac
     2341 atgttcatat cattcacgtc tttcaattat aaaaataaaa taccctaaga tattttgctt
     2401 tctatcttga ttattaccta agaactgggg tagctggatt cgaaccaacg catgagggag
     2461 tcaaagtccc ttgccttacc gcttggctat accccattaa tgaaatggag agagagggat
     2521 tcgaaccccc gaacccgaag gagcggattt acagtccgcc gcgtttagcc tcttcgctat
     2581 ctctcctaca atcaacatgg actattatat catgaaaatt tcaaaaaaac aagacttatt
     2641 ttgctaaatt ataattttca atcaaaattt ccacagcttt ttccaatttt ttataaaaac
     2701 tatcgacatt cccattcttt ataatggcaa attgtccgtc taattcggca atttctccga
     2761 taactttttt accgatagtc aatgtataac cttcaaaact gtctttacca acattaactt
     2821 tggcatccgc tacttgaatt tcgatttttt tatctttctt gctcatttca tacctctctt
     2881 cactttttct attttacaag aaaatcctaa aactagcaag aaaaaactct atatcaggct
     2941 tctctgatat agagttttat gtaaacaacc tcaatcgatt tagcatagtt aatagttagt
     3001 aaacaagcat aattgactat cctttttagg ttatcagtga gtctcaccgc ctactaactg
     3061 caaatcctta tctttgtagt ctacaatagt ttcaatagct acctctatgc ctcttacaat
     3121 atcacataga ctcattcctg cagtattcgg cttatttact acttgttcca tcatatatgg
     3181 aatatgcatg aaacctgctc tcatattagg gaatttttta tccactaaat aaagagcttg
     3241 gtacatcaaa tgattgcaaa caaaggttcc tgcactattg gatacaactg ccggaagtcc
     3301 ctgttttttg atagcttgta ccatcgcttt gataggtaaa ctactaaaat aggccgatgc
     3361 tccatcaata cgaatcggtg tatcaattgg ttgattgcct tcgttatcag gtatgcgagc
     3421 atcatcttga ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc ctgcttgtcc
     3481 aatacaaagt acagcatctg gttgatatcg taatatttct gcctctaaaa cttctgacga
     3541 cttataaaaa accgttggaa tttctaccca gcgaacttca gccccattaa tctcagatgg
     3601 taataatttt acagcctcca aagctggatt aatcttttca cctccaaaag gattaaaacc
     3661 tgtaaccaat attttcattt tattttcctt tactaaaatg cgagaaagta cattaagaat
     3721 atgtgaataa caatcattac tagagcaaca cctgcttgag cctttataac gccattctga
     3781 tctttcatat ccatcaatgc tgctggtaga gcgttaaaat tagcagccat tggggtcaat
     3841 aaggtcccac aataacctgc tgtcatggca agagcaccag ccacaattgg attagctccc
     3901 agagcaaata caaagggaac tccaacacct gctgtaataa cggtgaatgc tgcaaaagca
     3961 tttcccataa tcattgtgaa tagaaccatt ccaagaacat aagccaaaac tcctataaag
     4021 cgactatctg aaggaacaat accgctaatc agatgagaga taacatcacc aacacctgct
     4081 acagtaaaaa tagcccccaa agcccctaat aattgaggaa caatcccact tgttgaaact
     4141 tgctgagtca ttcgattatt ttctgataac agactcttag ggtgactatt ggtaatcaca
     4201 agaacagaaa ttgtagcaaa caaggcggca aggctaatcg aaatcttgct aaattctgga
     4261 atcatttgcg ctaagaccaa cgcaagtatt gccatcagca taactggaat aaaaatttta
     4321 tttttcaacc tgttagattc aatattggct ttcatttcat ctaaggatgg caaggttccg
     4381 atacggactt gcttaaacaa tgttaacagc gataatagga ttacaataat accaatactc
     4441 atatttggca tataggaacc acctataaac gtaatagaca atagagtcca aaatgcagat
     4501 gtcccaagtc gaactgggtt tgttttatct ttataactac aataggctgt atggagaaat
     4561 tgacaaccaa tcacaatata ggtcaactct aatagttgct ttgccaactc tgtcattttt
     4621 gttctcctcc cctagtcttt tttgatatca attttttatc aaataaataa ttgtaaatcc
     4681 ccactacaat aagtgttata acagcaacaa taatagatgt agaagcaatc cctgcataat
     4741 tgctttcata gcctaactga tctaatgttc cccctatcaa gaggactccc ccagcaccta
     4801 caaacgtatt ttgagcaaag aaatttccaa aattttcatt cgctgccgca cgcgctttta
     4861 ttgtctcatc ttcaacctct gttaactttc tacctaattg agactctgca gctgcttctc
     4921 ccataggttg aaccaaaggt ctgacaaact gagggtgtcc tcctagacga attgaaaaga
     4981 aaccagctaa ctctcgaata aagaaataaa ctgtatagaa gtttccaact gtcagacctt
     5041 taatctttcg aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct gacagcccca
     5101 caagaggcaa ggtaaccata aaaatcgtga gcactcgctg attgctaaat tcttttccca
     5161 aaatctccaa aaattcaacg agagaaacac ctgaaactaa agctgtaacc aaaccagcta
     5221 agactactgt tgcaattgta tcaaatttta aaataaaacc cacaacaatg attgctattc
     5281 ctattaatct aatccactcc atatcaaact cctttatatt caaaatgaca gtattttaaa
     5341 aattttatca agatcaatac cattccttat ttaatgtatt tttctagttc tttttggtat
     5401 ttgctattgg attccaattt ttctttttgc cattttttaa aaacctcgtt atattctttt
     5461 attgtaacaa tatctttttg caatttcatt cctttaaaga tatatggttc ccccttaata
     5521 ccaacttgtg agtatggttt tgagaatggt actacgttac ttacaactgg agaaccacca
     5581 gatgaagctg ttggcatcaa taatgaacta tctgtcgacc aagcttgagc tttggcatat
     5641 ttttcatatc tcttctctag gtcagtggtc tcagaaacag catcttctaa caatttctta
     5701 tatttatcca aaccaggttt agctacaaca tccttatctt ttcctttcgt aatgccaagg
     5761 tgtttcatgg cagaaccaga ttttggatcc ataatattca agtaagacgc tggatcttga
     5821 tagcttggag cccatcctgt actgttcaaa tcatagtctt tttgagaagg agcaacattg
     5881 ccgtatttat cattttccat caaaccatca ataacatttc caataacgtc tgtcctcgat
     5941 gttcgagtcg ctatactgta gcccaatgat gctggatcta ctgcatagac ataagaaaat
     6001 gttgtcggtg catctgcttc tttatcagtt tttccacaag ccactaaaat agctgacgtg
     6061 ctcaggacca ctcctgctgt taagagccac tttttctatt tcataaaaaa tctcctttgg
     6121 tttattttaa tctactttta caatccaacc ttctggcgct tcaatatcgc caaactgaat
     6181 acccgtcaat tcattatata atttacgcgt cacaggacct acttctgttt cactatagaa
     6241 tacatggaaa tcatcaccat gttgaatacc tccaattgga gaaataaccg ctgctgtacc
     6301 acaggcacct gcctctacaa aacggtcaag attatcaatt ggaacatcac cctcaatagg
     6361 agttaatccc aagcgatgtt ctgccaaata aagcaaggaa tacttggtaa tagatggcaa
     6421 gatagatgga ctcaatggtg ttacaaattc attatcagct gtaattccaa agaagttagc
     6481 tgatccgact tcttcaatct ttgtatgagt tgatgggtcc agatagataa catctgagaa
     6541 atgacgtgac ttggccattt ttcctggtaa gagacttgca gcatagtttc caccaacctt
     6601 agccgcacct gtaccatttg gtgctgcacg gtcgtactca tcctgaatca agaagttggt
     6661 tgggaccaaa ccacctttaa agtaatttcc aactggcata gcaaagatgg tgaaaatgta
     6721 ctcttctgcc ggttttaccc cgataatatc tccgacacca atcaaaagag ggcgaagata
     6781 taaggttcca cctgttccgt atggtggtac gtattcttca ttcgcacgga caactgcttt
     6841 acaagcttct acaaacatgt ctgtcggaac ttgtggcatc aagagacggt cacatgtacg
     6901 ttgcagacgt ttagcatttt catcaggacg gaacagttga acactgccat ccttagtacg
     6961 ataagctttc aaaccttcaa atgcttgttg tccatagtga agacttggag aagactctga
     7021 aatatgcaaa gttgcatcct ctgtaagctc tccttgatcc cattgtccat ttttgaaatg
     7081 agcaagatag cgataaggta atttcatata ggaaaaaccg aggttttccc aatcaatcgt
     7141 tactgtcata ttccactcct tattctaaaa acctatttct tatattctac actatttttc
     7201 taaaatagca agtatatttt gtaattttca gaaaatttct ccaataaaaa ccagctctta
     7261 gaactgattc ttcatttcac ttatttatct tcagtaacta cttcctgaag ataagcgtca
     7321 aaaacttctt catctgaaat cgtgtcagaa atgaagcttc cattgctagt gcgttctgac
     7381 aagttcaagt cttgcaatcg gctttcatag attgttcctt tattggattg gacaagcaga
     7441 gtttggtcgt tcacatccac ttccgtactg aagaaatcgc caacaaatcc ttgctctgca
     7501 actgctcctg ccaagaagac acgatgcggt ttgtttttca actcacgcaa gacttgtaat
     7561 cctcgtttgg cacggctggt tgctagaatt tcctcaatgg aaacacgttt caagcttcca
     7621 cgctgggtca agaggtagaa ggacgaagta ttacagataa agccagattg gaggacatca
     7681 tcttctttca aattcatagc cttgacacct gctgccttag caccgacaac cggaacctct
     7741 tcgatattga aacgcagggc ataaccattt tgactaacca agacaacatc atctagttta
     7801 atcggagcca ctgctacaat ctgatctgta tcgtctttga gcttagcata cttgacagac
     7861 ttagatctat aggtccgcca tggagtgaat tcttttcgct ctacccgttt gatttgacca
     7921 aggcgagtca ctgcaaagta ggttgtcgca tcgtcaaact gatccagtac ttccacataa
     7981 aggatttctt cattcgtttc aaagtttgtg atggtttggc tcagatgctc tccgatgtcc
     8041 ttccaacgaa tatctgccaa ctcatggatt ggtctgtaga tgacatttcc aagacttgtg
     8101 aacatcaaga ggtgctgggt tgtcttggca gattgaacaa aaatcaaacg gtcatcatca
     8161 cgcttgccaa tttcttccaa ggtggaagcc gcaaaggaac gtggactggt acgcttgatg
     8221 taacctgcct tggtcacgct gacgtaggta tcttcctcag cgataagact agctgtatca
     8281 atctcaattg ctttcgcagt gtcttctaaa gaactcaaac gaggagttgc aaatttcttc
     8341 ttgacctcac gaagttcttt cttcatgaga ttgtacatag tcctttcatc accgataata
     8401 gccgccagca tagcaatctt ctcacgaagc tctgcttctt cttcctgcaa gacaaccaca
     8461 tcggtattgg tcaaacggta cagttgcaaa gttacgatag cctcagcttg ttcttccgta
     8521 aaatcatagc taactttgag gttttccttg gcgtccgcct tattctcaga agcacggata
     8581 agagcaatga cttcatccaa aatcgaaatc acacgaatca aaccttcgac gatatggaga
     8641 cgtttctcag ccttttcttt gtcaaagcgt gaacgcgcca aaatcacttc tcgacggtga
     8701 gcgatgtagc tagacaggat tggaacaatc ccaacctgac gaggtgtgaa attgtcaatc
     8761 gccaccatat taaagttgta gttgatttgt aggtcggtgt acttaaataa gtagttgaga
     8821 acaagctcag tattagcgtc tttcttaagt tcaatagcga tacgaagacc atcacggtca
     8881 gactcatcac gaacctcagc aatcccagct accttgttat taacacgaac atcatcgatt
     8941 ttcttgacta gattggcctt attgatttca taaggaatct cagtaataac gatttgttcc
     9001 ttaccacctt ttagcttttc aatttcagtc ttggaacgaa caaccacgcg ccctttccca
     9061 gtctcataag ctttcttgat ttcatcacga ccctgaataa tagcccctgt agggaagtct
     9121 ggtccaggta agaattccat gagtttatca atctttgcag ttgggtggtc aatcatgtaa
     9181 actgcaacat ctatgacctc agctaaatta tggggaggaa tgtctgtggc ataaccagcc
     9241 gaaatcccag tcgaaccatt gaccaagagg tttggaaagg ctgctggcaa gaccgttggt
     9301 tctttctccg tatcgtcaaa gttccatgca aaaggaactg tctttttctc gatatcctga
     9361 agaaggtagc ctgcaatttc agacaaacgt gcctcagtat aacgcatagc cgcaggagga
     9421 tctccgtcca tagaaccgtt attaccgtgc atttcaacta gaatctcacg atttttccag
     9481 ttctgtgaca tacgaaccat ggcatcatag atagaagaat ccccgtgtgg gtggaaattc
     9541 cccatgatgt tcccgactga cttggccgac ttacggtagc tcttgtcaaa agtattgcta
     9601 tccttattca tagaataaag aatacggcgc tgaaccggct tcaacccatc acgaatatct
     9661 ggcaaagccc ggtcttgaat aatgtacttg gagtagcgac caaagcgctc tcccatgatg
     9721 tcctccaggg acatgttttg aatgttagac ataagataca aagcccataa aataccaagt
     9781 gaaaatagaa aattcttgaa gtaagcaaac tcacaagaga atttatcttt ttcacacagt
     9841 atctagggcg tgttcaactc ctttcaaaga atgtagagta ggtttttatg cagtaaaaga
     9901 tattttacgg gaattcgtcc cgtgttcagt tacgataagt aaccaaacta tcctgtttgt
     9961 atttttcaat atgaaaatat ggttttccaa aattagtctt agtttgtgtc ttagccgctc
    10021 ccttaaacgc ctctttgaga taagcactca tagcagattc ttcattaata atcctgcaat
    10081 tttttcaaac caagattttc aaactgcttt ttcacatagt cattcacatc cgactctaat
    10141 ttccagttta ctaacatatt attttctttc attaaaacac tgtcgcttct tctagcgtaa
    10201 acttgacatt atcttcaatc catttacggc gtggttctac cttatctccc atgagaacat
    10261 tgacgcggcg ttcggcgcgc gctaaatctt caattgtgac acggatgagg gtacgtgttt
    10321 ctgggttcat ggttgtttcc cagagctggt ccgcattcat ctcaccaagt cctttgtatc
    10381 gttggagggt agcgccttta ccgaactgtt tacggagttc ttctagttct ccgtccgtcc
    10441 aagcgtaggc cacttcttct ttcttgcctt tacctttgga catcttgtaa agaggtggga
    10501 gggcaatata gacatgacct gcctcgacta gcggacgcat gtaacggtag aaaaatgtca
    10561 agagcaaggt ctggatatgg gcaccgtcgg tatccgcatc ggtcatgata atgatcttat
    10621 catagttggc atcttcaata gagaagtctg ctccaacacc cgcaccaatg gtataaatca
    10681 tggtattgat ctcttcattt ttgaggatat ccgccatctt ggccttggct gtattgacaa
    10741 ccttaccacg aagaggtaga atagcctgga acttgcggtc acgaccttgt ttggcagaac
    10801 caccggcaga gtccccctca actagataga gttcattctt agcaggattc ttagattggg
    10861 ctggggtcaa tttcccagac aacaagccct tatctttctt gtttttcttc ccatttcggc
    10921 tctcatcacg cgccttacgt gctgcttcac gagcatcacg ggccttgata gccttgcgga
    10981 tgaggttaga agctaattcc ccattttcca taaggaaaaa ggtcaactta tcagccacta
    11041 ttccatccac aactgggcga gctagggggc ttcctagttt atccttggtc tgtccttcaa
    11101 actgcaagtg ttcttcagga actaagatag aaagaacggc cgctagtccc tcacgatagt
    11161 ctgaaccttc aaggttttta tctttttcct tgagaagacc tgttttacgt gcatagtcat
    11221 tcatgacctt ggtaatggca gacttgagtc ctgtctcgtg cgttccaccg tccttggtgc
    11281 gaacgttatt gacaaaggat agaatgttat ctgagaatcc gtcattgtac tggagggcta
    11341 cttccacttg aaaaccattg tcttcccctt caaagtaaag aactggcgtc aagatttcct
    11401 tatcttcgtt gagataagaa acaaaatctt gtactccatt ctcatagtgg aactcaatcg
    11461 cttcatctgt tcgcttgtcc gctaaagaca aggtcacatt tttcaagaga aaggctgatt
    11521 cattaaggcg ctctgaaatg gtattgtact tgaaatctgt cgtagaaaag atagtcgcgt
    11581 caggcataaa agtaactttg gtgcctgttt tagacttgag tgctgtaccg attttcttca
    11641 aagtcgtgac aggttttcca ccattttcaa aacgttgctt gtaaactgcg ccatcacggg
    11701 taatttcaac ttctaaccag ctagaaaggg cgttaacaac ggaagaaccc actccgtgaa
    11761 gtccacctga tgtcttatag ccaccttgac cgaatttccc tccggcatga agaatggtaa
    11821 agataacctc aacagttgga attcccatag cgtgcatacc tgtcggcatc ccacgtccat
    11881 ggtcttgaac cgttagacta ccgtctttat tgatagttac atcaatacga tcaccaaacc
    11941 cagacaaggc ttcatcgact gcattatcaa cgatttccca aactaggtga tgaagaccag
    12001 cgccatcggt cgatccaata tacatccctg gacgttttcg gaccgcatcc aacccttcta
    12061 gcacctgaat agcatcatca ttataattgt taatattgat ttcctttttt gacacaagga
    12121 acctcctatt cgttcatctt tactattcta caggttttcc aaggattttg caaaattttt
    12181 ctttctccga tgtgacaatt tcagcagaga ttctctgctt ttctttccca attcatgata
    12241 taataggagt atgattacaa tagttttatt aatcctagcc tatctgctgg gttcgattcc
    12301 atctggtctc tggattggac aagtattctt tcaaatcaat ctacgcgagc atggttctgg
    12361 taacactgga acgaccaaca ccttccgcat tttaggtaag aaagctggta tggcaacctt
    12421 tgtgattgac tttttcaaag gaaccctagc aacgctgctt ccgattattt ttcatctaca
    12481 aggcgtttct cctctcatct ttggactttt ggctgttatc ggccatacct tccctatctt
    12541 tgcaggattt aaaggtggta aggctgtcgc aaccagtgct ggagtgattt tcggatttgc
    12601 gcctatcttc tgtctctacc ttgcgattat cttctttgga gctctctatc ttggcagtat
    12661 gatttcactg tctagtgtca cagcatcgat cgcggctgtt atcggggttc tgctctttcc
    12721 actttttggt tttatcctga gtaactatga ctctctcttc atcgctatta tcttagcact
    12781 tgctagtttg attatcattc gtcataagga caatatagct cgtatcaaaa ataaaactga
    12841 aaatttggtc ccttggggat tgaacctaac ccatcaagat cctaaaaaat aaaacgccag
    12901 ttctgtactg cccccaaaca gttagacaaa taatttatcc aaaggattta gttctgtatt
    12961 gcacagggct aagtcctttt agttttacct taattcgttt gttgttgtag taatcaatat
    13021 agtctataat ggcttgttcc aattggttaa gtgatttaaa tgttttctca tagccataaa
    13081 acatttcgga ttttaaaatg ccaaagaaag attccatcat accgttgtct tggctgtttc
    13141 ccttgcgtga catagatgct tgaattccct tactctctag gaaccgatga taagaatcgt
    13201 gttgatattg ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc ttctctgtaa
    13261 aggcctgttc taacatactc ttcacttgtt ctaagttggg cgaagttgaa agattatagg
    13321 cgataatttc gctattaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtactta
    13381 ctggaatggc aaattcagtc acatctgtgt agcactgttc cattgtttta gagccttcaa
    13441 attggccttg aatgagattc tctgctttct tgccaacgtc tcctttatga gaagaatatt
    13501 ttcgtttctg tcgcgtttta gcttgtaaat tgagtacttc atcaagtgtt gaactctttt
    13561 atgatttacc agataaccac gatttcttag ttctaaataa atccgacgat aagcataatt
    13621 tcccttgtgt tcgataaaga tggattgaat ttcagcttta agctcttggt ccttatctgt
    13681 tttgtctagc tgtttcaagt gatagtagta ggtcgaacga gctagtttaa tggcttttag
    13741 aagaagatct aacgaaaact cagtcattaa ttcttgaaca atttctgtct ttcttctttc
    13801 tctttttcct ccttcaatcg gagttctctt aactttttta ggatggcatt ctccgctctc
    13861 aggtactcat tttctgcttg aagacgttct aattctgtcc tctcttcagg tctcgttttt
    13921 ggattacgtc ccattttagg tactctccct cttggtttct caacaatagt atacccgttt
    13981 ttcctgtatt gtgctagcca gttaagaagt atcgtacgac ttgggagacc gtattcaaga
    14041 gaaactctat ctttagtcca gccttcatgt cagactttat
//
LOCUS       DAVLHB010000050        13743 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLHB010000050 DAVLHB010000000
VERSION     DAVLHB010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.050"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(415..795)
                     /locus_tag="VXE36_001719"
     CDS             complement(415..795)
                     /locus_tag="VXE36_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV0779973.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(941..2293)
                     /locus_tag="VXE36_001720"
     CDS             complement(941..2293)
                     /locus_tag="VXE36_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEV0779974.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLVKLRAKEAIFEKFEQSLNEKYNRMSNSGEEQEYYGKVEYYLSQLNSENYNN
                     STQYSKIQDEYTKLNKITAERNQLDADLQTLQNELLQLQQQGDSPSLSDTTSADDKAK
                     LETKILEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(2290..2757)
                     /locus_tag="VXE36_001721"
     CDS             complement(2290..2757)
                     /locus_tag="VXE36_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0779975.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(2750..4969)
                     /locus_tag="VXE36_001722"
     CDS             complement(2750..4969)
                     /locus_tag="VXE36_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0779976.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYENMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            5435..6298
                     /locus_tag="VXE36_001723"
     CDS             5435..6298
                     /locus_tag="VXE36_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0779977.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(6587..7978)
                     /gene="argH"
                     /locus_tag="VXE36_001724"
     CDS             complement(6587..7978)
                     /gene="argH"
                     /locus_tag="VXE36_001724"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0779978.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TIGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(8007..9203)
                     /locus_tag="VXE36_001725"
     CDS             complement(8007..9203)
                     /locus_tag="VXE36_001725"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0779979.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQIGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPIPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPSSLYDENLATYTSADTFDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            complement(9220..10026)
                     /locus_tag="VXE36_001726"
     CDS             complement(9220..10026)
                     /locus_tag="VXE36_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0779980.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(10233..10874)
                     /locus_tag="VXE36_001727"
     CDS             complement(10233..10874)
                     /locus_tag="VXE36_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0779981.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(10871..12979)
                     /locus_tag="VXE36_001728"
     CDS             complement(10871..12979)
                     /locus_tag="VXE36_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0779982.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHALLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(13031..13318)
                     /locus_tag="VXE36_001729"
     CDS             complement(13031..13318)
                     /locus_tag="VXE36_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0779983.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
BASE COUNT         4325 a         2948 c         2104 g         4366 t
ORIGIN      
        1 ctgccaagcc acatagtgtg tttactacta tgtgtccatg tcaccatgaa tcgccgaacg
       61 atttaacgag aaagtatgac ttttacgttt atcccaactc aattatgaca tttttttcaa
      121 aagtcaatat atctcacttt ttcaacgaca agaaagaggc tgataatcta ccaacctctt
      181 gtttttaaat acatttcaag tccaaactat tctttataga aaaaagtcct ataaattcga
      241 gcaatagtta aaatacaaac aaatataatt cccaaaatag ataacactat tttcacaaaa
      301 ttcatttcag aacctattat atatacgtga aaaaaagggg ctattcctac acatatatac
      361 aataaataac ttacaaagtt tatttcacca attcctgcaa aaaaatgttt cattttaagc
      421 aaaaatataa ccatctaagc taccgtcagc ccaatcagcc ccatatgcga ttgctccacc
      481 tagtgaaaat ccagtaacag ttagtgcaac gtttagtgca gtattgacta aatggccagc
      541 tgcactacct acatgtttaa ttattaaact acgtaatgtt ctcgtaatag cccctctatt
      601 agctgagata gcttttttta tcgcataagc agaataaatt gttgcaccac cactatagat
      661 ggccaaacct acatccagaa ctgttgcaaa actacctcta ctattccacc agttacgacc
      721 aacaccaccc ccatcaagat acatcatctc ttcttgctca agagcaacat aattatttgg
      781 taatacgagt tccatttatt ttctcctttt ttattaagca tggttaggat agtttcctaa
      841 caagtgagca tcgactttgt ttatagcact tagttaccta gataagatat cttcccttta
      901 tcttacttta ttttataggt gacttaatgt ttaaaaccaa ttattgcttg aaacttaaca
      961 tttccaaaat ccaatcaaga taggtttctt tatcatagac aatccgcact tcaactggca
     1021 tatccttttg gaggacgact gtctcacttc catgttttag agttaaggtt tctaattcta
     1081 tcatgacttt ataaagacta atattgccct ctttcgtttc ttgggaaatt gttcctgaat
     1141 caatctgtct gacttgtccc tttagtgttc catatttttg actatttaca ccagtaatag
     1201 caacatcagc ttttgctcct ttcgaaacac gagaaatatc actcgcaagt acaaaagctt
     1261 ctacatagta acctttttct ttccctgaaa cttctgctat cgtttgcccc tgctgaatag
     1321 acattccttg tttcaaaggt accaaataat gcagagtacc ttcatttggc gctaatatac
     1381 tatgagcttt atcttgacct gttgccactc caagattagc ctcaagctct gtaatacttt
     1441 tattgttgtt tgaacgagca gtacctaact cactaactaa ttgagcataa atattataag
     1501 cctgagaagt tggatcatta taggtacggt tcatatcttt aatattgctt tgttgactat
     1561 caatctcgct attcttagaa gtaatatttg tttttaatgc ttcgattttt gttgttattt
     1621 ctaatatctt agtttctaac ttagctttat catcagctga tgtcgtatct gataaggaag
     1681 gggagtctcc ttgctgttga agttgaagca attcattttg tagagtttgc aagtcggcat
     1741 ctaactgatt tctttcagct gttattttat tcaacttcgt atattcatcc tgaatctttg
     1801 aatactgggt actattatta taattttccg aatttaactg agataggtag tattcaactt
     1861 tcccataata ttcctgttct tcaccagaat tagacatacg gttgtatttc tcatttaatg
     1921 attgttcaaa tttttcaaag atagcttctt ttgcacgtaa cttcaccaat tgtttattta
     1981 aagagctcgc ttgtaaacct tcttgtccac ttgataacga aataatgaca tctccagcat
     2041 ttaccatatc tccttctgac ttatgtaaag taactacctt ccctgaacca attgctgata
     2101 ggaactctgt acctgttata actgaatttc cattcgcttt tacaatatag tttttgggta
     2161 tataagctgc gccaaccaat gcaccgctta agataatagc agttgaaata atgagaataa
     2221 acgcaaaagc tggtggtctc ttatcaaaga aaatacgaga ataacgtaat tctgatttat
     2281 tatataattt cataggctta caattggtct aaaaatatct actaccattt tttcaggaga
     2341 agaattaaca taaactgtat agacaatccc atccgtttga atatcatttt catagacata
     2401 tagatccaat ttagaatacg catactgtag atactctgga ctgtcttcaa aacgaacata
     2461 taaacaatat ggaacagaga tagaatcctg tacatcataa atgttactgt actgttgagc
     2521 attatgagct tgaatataaa actcaaaatc agtcgttatt aatccatcat catgaatagt
     2581 agtaccacaa ctttttacaa ttaatggacc aaaaatttgt gcttttaaca actgcaaatg
     2641 ttgatgaaat ttattaattt cctgatctac atcttctact tttgtatcat gtaacttttt
     2701 acagataact gactttagta ccagtttttt attatctttt acctctaact tagccataag
     2761 taacctcctc tgtatctaac acagcctgtg actgaatttg ttgattcact tgaacgctct
     2821 gcaaaccaac cattctagca tactttccat ttttcgccat tagttcttca tgagtcccat
     2881 attccacaat agtcccattt tctaaaaagc atatcttatc acatcgaaga attgtagaca
     2941 gcctgtgggc tactacaatt gttgtcttat ccattatttt attaaagatt aaatcctgaa
     3001 taatctgttc actaaatgaa tctaagttag aggttgcctc atcaaatata tacaaatcag
     3061 ctttactcag tagtgctctt gcaatagcca atcgttgttt ctctccaccc gagaaatttt
     3121 gaccgccttc ttctacaaag gagccataac gattttgaag acgttgaatc gtatcatgaa
     3181 taccaacaat acgacaaact ctcaccatat tctcatatgt aacagaagga ttaccaattt
     3241 ttagattatc aataattgtc cctgtaaaga gttctatggt ctgaggaatg taggaaattt
     3301 tcttacgtag tttaccatag tcaagatctg ataagtcatt ttctcctata cgaattttcc
     3361 cctcactcgg atttataaat cttaataaca aacgaactag cgtacttttt cctgctccgc
     3421 tttctccaac aaaagctatt ttttctcctt gtttaattcg caaattaaag tccttgataa
     3481 caggagggcg tgaaccatag gcaaatgtta catctttaaa ttcaatgtca tcacataagg
     3541 tgaagtctct aatactataa tccaaggcaa tgtcttcacg atctacttcc atcaattctt
     3601 gaagccgact aaccgcaacc tgtacctctt gaaaggttaa ctgcaagcca actaaattct
     3661 gaataggttc tgtaaaatat tgacttaatg tctgaaaaac caagaggtcc ccaatagtca
     3721 tttttccatc aatgataaat aaggcgccca ctcccataaa taataaccca cccatggttg
     3781 aggtcattga agatattgta gattgaatat tctgcaaaac accctcttta taaccaattt
     3841 ctaaagtgtg aacaaatttt tcttcaattt tgtttaaacg ttgttcctca tcatgctgag
     3901 acttaatggt atcaatgtta cgaatagatt caattaactg tgaattaaga agtccatttg
     3961 cttccatttg ttcatgatta atttttttat aaggcttttt aaaacagtat ataagaatga
     4021 tgttaacaat aaccataaaa actaatatca gaaataaaga ttgattaata gtccaaagga
     4081 caaccgcact aataactgac aaggtgatat ccatgactaa tgaaatagag actgacgtaa
     4141 acacattctt tatcgtcatc gcatcttgaa atcttgttaa aacatcacca actctacgac
     4201 ttccaaaaaa actataagga agatgaataa tatggtcata atatcccatt aaaaccggta
     4261 tatcaatttt tcgagataga aacaaaagaa cgtgctgacg aaatgcagat agaagagtct
     4321 gtaagaacga cactattcca aatactatca aaaacatata cagactattt tttaaagcat
     4381 atggaatcac ctcgtccatg ataacttttg aaaagagact cgataaaata ccaatgatac
     4441 ttaaaacaaa ggaagctaat atgactgtac taatcaatcc tttttgatta aaaattaacc
     4501 ttccaaataa atcaagaagt ccttttccct ttagtttccc tctttcaaaa tccgaatttg
     4561 gaaccataaa aagagtaata ccttgataaa tttctcccag ttcgtcactt gacatcttgc
     4621 gtatgccact agcagggtct gctacgtaga acttactatt ccttttgata ctatgtaata
     4681 ccacaaaatg attttgacct aaatcattct taacttgaag aatcgcagga aatgttaatt
     4741 ttggagtcaa atcttccagt gctactcgaa cagcttttac tgtaaaattc aacttattca
     4801 gacctgaaac aataccactg acagtcgttc catacatgtc tgtaccaata atttccctaa
     4861 tcttcatgat tgatagttcc tttttgtaag ataaaagaac tgttgaaaca actgccgcag
     4921 cacaatctga ctggtcatgt tgcatcgtac aaggatattt ttttaacata gaaatactca
     4981 attctttaga attaatctaa cttttctttg atgtcaccca aacctcaatc actgcccagt
     5041 agttcttgaa ttaatttatt ttcaaccgta tcattctttg ttcttgatat ctttccaagc
     5101 attgtagtac agcagatttt tgcccaagga ctgagcctcc tttaacaact caaactccct
     5161 tacattatat cggccagccc catggaaaga ttatagccag actaatcaat aatataatac
     5221 atactagaat acaaaatatt tttttattca tactttttct cctatcttta ttttctacct
     5281 acatagtacc tcttattaag ctcattttaa aattacgtta acttttttca caaatttatt
     5341 tcgactttct tttttacttt ttacattgct atgatacaat atttttaaca aaattttatt
     5401 gtttgttaac ttttttcacg aaaaggagaa aatcatgcgt tatgatttcg gaaaggtcta
     5461 taaagaaata cgtgagtcaa aggggctgac ccaagaagag gtctgtgggg gtgttctctc
     5521 aagaaccagc ttatcaaaaa tcgaaagtgg caagacaacc ccaaaatatg aaaatatgga
     5581 atttcttctc cgtcaaatca atatgagttt tgaagagttt gaatatatct gtcaacttta
     5641 tcaaccaagt caacgcacag agattatgca aacctatctc aatatgcgtt ccattatcgg
     5701 gaccagcgat cttgtcaatt tatttcaaaa atgccaagac tacctcaaga cccaccacga
     5761 tctccctata gaagaaatca gagatatgct tgaagttgtt atttatctcc gtcaacacgg
     5821 ggcaggggaa ctatcaaaac acgcagaaca ggttgtcaaa aaactttgga aaaaaattga
     5881 aaaacaagat acatggtatg agagtgatct aaaaatcctc aataccattc ttttcagttt
     5941 tcccattgaa tacctccatc tcatcactgg aaaaatattg caacgcctag aagtctataa
     6001 aaactatcaa catttatatg acttgcgaat gacaattcta ttaaaccttt ccacactcta
     6061 tctatacaat caagataaaa acatgtgtaa gcaaatctgc tacactttac tagaggacgc
     6121 caagaataag aaaagctacg ataggctggc tatctgctat gtccgtattg ggatttgtac
     6181 agacgattct aaacttatcc aaaaagggtt ctcccttctg gagctaaccg aggaaacttc
     6241 tatgctgtct catctcaaaa aagaagtaga gatctattac caagcgaagg aaagataaaa
     6301 aagccgaggg atttcctcga ctctttacat attatttgtt cgttagttct taataccagc
     6361 cattgttaag ccagaagttt ttagctctgc caagccacat agtgtgttta ctactatgtg
     6421 tccatgtcac catgaatcgc cgaacgattt aacgagaaag tatgactttt acgtttatcc
     6481 caactcaatt atgacatttt tttcaaaagt caatatatct cactttttca acgacaagaa
     6541 agaggctgcc aatcgaccaa cctcttattc tgaacccatc actccatcac tttttagctt
     6601 cattcgcttt cttagcgact gcaatctggt attcgacttg gtcaaaccct gtgcctccca
     6661 aggaatttcg tctttgaaca gcagttttag gttgcaagta gacatagata tcctcggtaa
     6721 tgagagaatg ataggtttgt aattcctcca aagtccaatc ttgaagattt ttagcagact
     6781 tgatagagtc tagcactaat cttcccacaa cctcatgagc ttctctaaat ggcaagcctt
     6841 tccctgccaa ataatctgcc aactcagttg catttgaaaa gtccttctct gttgattctt
     6901 gcattttttc cttgtttacc tgcaaactag ataacatacc tgccaacaca tcgagggaat
     6961 ttaaaatcgt ttcgaccgta tcaaacattc cttccttatc ttcttgcaaa tccttattat
     7021 aagctaaagg caaggacttc atgactgtca acagtccaaa caaatgccca taaactctgc
     7081 cagtctttcc tcgaatcaac tcagccatat ctggattttt cttttggggc ataatagagg
     7141 aacctattgt aaacgtatct gacaaggtaa tgaattggta ctcaaaacta caccaattaa
     7201 tcatttcttc gcaaaaacga ctcatatgca tcatgagtat gctggcattt gatagaaatt
     7261 ctaagataaa atcgcggtca ctaacagcat ccaaagaatt tgtataaggt tgcttaaact
     7321 ccagcaaatc gctagacaat tggcgatcaa tggggaaagt cgttcctgcc aaagctgccg
     7381 cacctaaagg gcataggtct gtatgcttct ggttaaattc aaaacgttca ctgtctcttt
     7441 gaaacatatt gtagtaagcc atcaggtggt aggcaaaact aataggctgg gcatgttgca
     7501 gatgggtata gcccggcatg atcgtcgcca catgattttc cgccaagtct aataaaacac
     7561 ccttaagatg agccagttta tctaggacat agcctagttg ttccttgaga tacaagtgca
     7621 tatctgtcgc aacttggtca tttcgagaac gagccgtatg taacttccct gcaaggggac
     7681 caattttttc tgtcagcaac acttccatat tcatatgaat atcttcgttt gcgatatcaa
     7741 agtcaagttg acctgcctct agctcttcta aaagctcttt caagcctact tgaatctttt
     7801 ctgactcctc caaactcaaa atgcccgtct gacccaacat ctgaacgtgg gctaaagaac
     7861 caatcacatc aaatttagct aatttctggt caaaagatat actcgcacca aagcgctcta
     7921 cccagtcttc gacagtacct tcaaagcgac caccccataa ttttgtattc ttagccatat
     7981 cacatccacc tctctatcca atcgtcctat ttggcgcttt tttgaacctc agaatgaacc
     8041 ttggttggaa gtccccataa cttaataaag ccaacagccg catcttggtc aaaggtatct
     8101 gcactagtat acgtcgccaa attttcatcg taaagagaac ttggtgattt ccgagccacg
     8161 acctgagcgc tccccttata cagtttgact tttgcagtcc cattgacaac tttttgagtc
     8221 tctttaatat aagcaatcaa ggcttgtgta gccgaactaa accacaaagc attataaatg
     8281 agatttgata attcattttc tatgattggt ttaaaatgag ccacttctct cacaagcgtc
     8341 aagtcctcaa tttccttatg agctgtcagc agggtcactg cacctggaca ctcatagatt
     8401 tctcttgatt taatcccaac caagcgattt tccacgtggt caatccgtcc aaccccatgt
     8461 tttccagcta tttcattgag tttttgaatc aaatctgcca attttaacac ttctccattg
     8521 agggaaactg gaacaccttc actaaactca atctcaatgt attctggcat atctggagct
     8581 tgctctggag aagttgtgat gccaaaggct tcttctggag cctgattcca tggattttcc
     8641 aaaataccac actcattggc acgtccccaa agattttggt cgacagagta gggattgtca
     8701 aggtcagcag gaataggcac cccattttcc ttggcataat aaatttcttc ctcccgagac
     8761 catttccatt cacgaactgg agcaatcact tttaaattga gatccaaggc tgcaatcgat
     8821 acttcaaaac gtacttggtc attcccctta ccggtacaac catgagcaat tgtagtcgct
     8881 cctatctgat gcgctatttc aaccaatttt ttagaaatca gagggcggct caaggcagat
     8941 accaagggat acttttgttc ataataggca tgtgactgat gagccactag cacataatct
     9001 gtagcaaatt cgtccttaac atcaatgaca taagattcga ctgccccaac cttaagagcc
     9061 ttatcatgga tgaaatctaa gtctttccct tcacccacat ccatacaaac tgcaacaaca
     9121 tcatagtctt tcttcagcca ggtaatagca actgatgtgt ctaaaccgcc agaataggcc
     9181 aaaattactt tttctttact catgttcttt tccttctttc tatttttcaa tggacgcttt
     9241 aaaggcatcc tcaatgagtt tgtctaattc cccagactcc ttcaactttt gaatggtttt
     9301 atcgactgcc tctttcaatt ccttgctatc ttttttcatg gctaccgcat aggaatcatc
     9361 ttgctctttt tcaaaattga ggtctgcgat tgctaaatca ggattatttt ccacaaatcc
     9421 cttggcaacg ggttcttcaa aaataacggc atccacttgc cctgatttta aatctgtgat
     9481 taaattccca tttttaggca gagatacgag ggaagaattt tgtagcaaat ctttcgccat
     9541 cgtctcttga atcgaacctt tctgcgctcc gacctttttc tgcgccaaat cgttgacaga
     9601 ctgataagtg gctaaatcag attttttgac aatgagttta ttttttgcag tatagtaggg
     9661 agttgaaaaa tcaaacacct tgctccgttc atctgtctta gaaacacctg atatggcaag
     9721 gtcagctttt cctgattgaa cgctagccag tacattgtca aaactcatag gagatagttc
     9781 caattcgaca cctagttctg ttgcgatagc cttggctaat tcgatatctg aacccacaat
     9841 ctgatttttc ccatcaacca ctttttggta ttcaaatgga gcaaaatctg gattgagggc
     9901 tacaaccaat tttcctttgg acttgatggc ttcaattcca gccgattgat tgttgctaca
     9961 agcaaatagt agggggagca tcactaaacc aaacatcgtc atcaacacct tcttcatctt
    10021 attcataata aagtctcctt tatgtttatt ctttttggtt gtataaataa tactcctata
    10081 ctcatccttt gtcaagccta aattgaaaaa attttcaatt tgaaacaaaa aaaacctaga
    10141 aatactacat aaaatgtcat tcctaggcgt atttatgcta tttttctctg gaaaacatga
    10201 gtattcagcc agtcaaaagg agctgaatga actcattttc cctcgcccaa ttcaatgaca
    10261 cgatgacatt gttgggctac ataagcatcg tgggtcacga taatgactgt tttcccttct
    10321 cgattcatct ctaagagaaa cttcaagacc aaatctctat tttcaggatc cagcgaacct
    10381 gtaggttcat cggctaaaat cagctggctg ggttttaaga tggctctagc aactgcaatt
    10441 cgttgttgtt cgcccccaga caactcggag accctttgat gcaaagtagc tgacaaacct
    10501 actctctcta aaatctcttc cacctttttg agcttgtctt tcttaggcaa tttcacatat
    10561 ttcagcgcca gcatgagatt gtactcgacc gtttcatcat caatcagggc aaaattttga
    10621 aacagataag agatatgttc acggattatt gtttgcgact tagcagaatt aaccgctaga
    10681 tttgtctgac caaaaatctc ataccgtccg ctataatcac catctatcaa acccaataaa
    10741 tttaacaagg tcgacttccc actaccactc ttaccaacaa tagctaccaa atccccctga
    10801 tcaatcctga gagataagtt atccaaaatc acttttcccc caatggtttt ggtaatattt
    10861 ttcaactcaa tcataagatg ccccctttca ataactctac tagacttctt ttctccatcc
    10921 tagaagctaa gcctagcaca aatagtatat ccagacatgt aaaacctgca aacagcagga
    10981 gtggcaagag cgcatgggca aagaaaatca agactagaag agggaaacta tagcccagca
    11041 agagcagaac gaggagagga cggtagcgat cgaccagttt ccaccccata aacttcttgg
    11101 taatgatatc cctgcgcttc aataagaaag ttgttactag taagaagtag gaaatcatca
    11161 tgctaaggag accaaacaaa gcaaagagta ggttaaaatt ccgaacagca tctcgataag
    11221 aatccacttt ctcttgttga atggcttgaa tagatgaaaa ttttaaataa tttccatctg
    11281 acaatttctc aactaactct gtaatctctt tttgatgttg aaccgtattt tcaattttaa
    11341 tcggattatt taagccagtt gttgacaggg aggctttctc atcccacatc atatcagaat
    11401 cattgaccaa gctaataatt ggattggaga gattttcctt tcgcttatca ctatatggga
    11461 aaaatgacca atctccttca taataggcaa tctcgacatc catctcctct atcgttcgtt
    11521 tttgctgctc ttcatacttc atcgaatgaa aggcaattaa cttccccaag agctgatttt
    11581 tatcttcttc acctttcgta cttgctggca tcaaaataac ttttttaata ccggtatctg
    11641 gtagcttgaa tcccttgctc tttagaaaat tgcgattggc atagtaaaca tccaccgtat
    11701 ctgttaactg atattgctga atctgttctg attggacaaa attttttaca ggaagactgc
    11761 tactctgcac atagcccgcc tgcgtttttt ctaccaaatc ctgataaaat cgatagaaat
    11821 aatctgtaga tttccctgac cctgctagct cttcttgcca cagattatca ttgagtttga
    11881 aggtttctaa ggtcaggtaa ttaccttgac ttacccactg ttgctgataa gcaagttctt
    11941 tgttttcttg ttctaaactt ctgcccaccc caatcagtaa ggccgtcagt aaaatagttg
    12001 tccctatttt catcacataa ttgaagataa gaccaaattt gaaagatgaa aaacctttca
    12061 gcagagagct gattgtcatt ttttggatta agaggtaagt caaccaactg ataaagagat
    12121 aaagctgcaa cagcaaaaaa tgagacaacc acagcatagg aaacaaatct tttggcttat
    12181 aatcaagcaa gaaaaacacg cctagattga tcacaagagc cccacctagg aggaggtaaa
    12241 ggttgccttt tacaacatca gctaaaacag ccctatcttg aaaaccaagt aatttttgta
    12301 ccccaactct tttcatctcc atcatcggtt gatacactgt cactaacaca agaagcaaaa
    12361 tagccaagac aaaaacaatg gcagataaaa gcaaatctcg atttatgact tccactgcac
    12421 ttttgtaggt cggctctagc aaggtagcct ggtctatctt gaaaaaatcg ctccatttct
    12481 gtacaatcct atccttgtcc atctcttgtg tagaagttat cgtatagcga ccatttaaac
    12541 tacgagatgt atccttgata taggtttgaa aagtcataag ctgaataggt ttggctttta
    12601 gaaaggtcgg aatcgtacca agtttattgg aaatttcttt attactatag actccttcac
    12661 catctgtggt aaaatcaaga gaagaaatcc caaactcttg gtaggggaag gtatctttat
    12721 caaaaacacc agacttgacc acctcatcac cactgtctgt tttgatgatg gagactttat
    12781 actcctttga tacatcctca aaaaatcgaa gaacagacgc tgcaggttcg ttaatatctt
    12841 tcaaatacaa atccaaagaa tctacagtct ttcccatttc ttgaatccga accacttctc
    12901 gtgtatagtt tacattaaaa acaaaaaaag tggtacacag aagcaggagt aacatacaga
    12961 aattactgat ttttttcata aaagtgcctc cactacagtt ttccctctcc aaataggaga
    13021 gggaagaatt ttactcaaat ccatagaaat attccattcc tgttggcgga atcttggtga
    13081 gggaagctct agcccatgcc tcaggttttg cataatcctt agaggttcta cccccatgtc
    13141 taacagttgc tgtatgatat cgagtagaat gtaagtaatc agaatatcca aaagttcctg
    13201 tccaacctac tccatagttc cattgaccac cctcaaccca tactgctaaa gcatttgtag
    13261 tagcaagtat accacatacc attaaagatg caacaccaat tttaactaat tttctcatga
    13321 tttatttctt ctattatcga gagctgttcc gtaaaaacag ctatagtaat ttatcaacaa
    13381 gtatcgtagt ccattggact caccttcctt ctatctcatt tcatttttta acaacgaact
    13441 tactcttaac cgggagaatg gtgcgcttct gtatcaggtc cttgaacaac cagagtagta
    13501 ttaagcacac tctaactatt actcaagaat cagtccaata aacaatatgg atagcgcttt
    13561 caaattttta aactcctatc ccgtcctttt atctatataa taagtgaaaa tataataact
    13621 gtcaagtaat cgaagtgaat tttataaaaa aaaattacaa gccaaatttg caaagtttac
    13681 aataagccgc tagggcaatc gtctatcaga atgtccgttt atttgtcaat aatccgagaa
    13741 aat
//
LOCUS       DAVLHB010000051        13598 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLHB010000051 DAVLHB010000000
VERSION     DAVLHB010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.051"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..187
                     /locus_tag="VXE36_001730"
     CDS             <1..187
                     /locus_tag="VXE36_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0779984.1"
                     /translation="EKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIF
                     IALNIKKERTKFVLSRA"
     gene            complement(237..947)
                     /gene="deoD"
                     /locus_tag="VXE36_001731"
     CDS             complement(237..947)
                     /gene="deoD"
                     /locus_tag="VXE36_001731"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0779985.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1601..2113)
                     /locus_tag="VXE36_001732"
     CDS             complement(1601..2113)
                     /locus_tag="VXE36_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0779986.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFCFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGSGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(2138..2940)
                     /locus_tag="VXE36_001733"
                     /pseudo
     CDS             complement(2138..2940)
                     /locus_tag="VXE36_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963254.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(2959..3096)
                     /locus_tag="VXE36_001734"
     CDS             complement(2959..3096)
                     /locus_tag="VXE36_001734"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0779987.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLPEASEVLENKREESKVEI
                     T"
     gene            complement(3593..4402)
                     /locus_tag="VXE36_001735"
     CDS             complement(3593..4402)
                     /locus_tag="VXE36_001735"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0779988.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(4418..4960)
                     /locus_tag="VXE36_001736"
     CDS             complement(4418..4960)
                     /locus_tag="VXE36_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0779989.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            complement(4962..6173)
                     /locus_tag="VXE36_001737"
     CDS             complement(4962..6173)
                     /locus_tag="VXE36_001737"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0779990.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIYDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(6187..6870)
                     /gene="rpiA"
                     /locus_tag="VXE36_001738"
     CDS             complement(6187..6870)
                     /gene="rpiA"
                     /locus_tag="VXE36_001738"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0779991.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(7152..8024)
                     /locus_tag="VXE36_001739"
     CDS             complement(7152..8024)
                     /locus_tag="VXE36_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0779992.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     ATLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(8166..9023)
                     /locus_tag="VXE36_001740"
     CDS             complement(8166..9023)
                     /locus_tag="VXE36_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0779993.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(9177..9911)
                     /locus_tag="VXE36_001741"
     CDS             complement(9177..9911)
                     /locus_tag="VXE36_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0779994.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(9911..10594)
                     /locus_tag="VXE36_001742"
     CDS             complement(9911..10594)
                     /locus_tag="VXE36_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0779995.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            10784..11014
                     /locus_tag="VXE36_001743"
     CDS             10784..11014
                     /locus_tag="VXE36_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0779996.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            11243..13501
                     /locus_tag="VXE36_001744"
     CDS             11243..13501
                     /locus_tag="VXE36_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0779997.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQNTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
BASE COUNT         4023 a         3082 c         2478 g         4015 t
ORIGIN      
        1 agagaaaatc gtcaacgccc ttcaactaca ctattctaac gccaaattgg aagcgaccaa
       61 taatctcatc aaacttatca agcgcaatgc ctttggtttt cggaactttg aaaacttcaa
      121 aaaacggatt tttatcgctc tgaatatcaa aaaagaaagg acgaaatttg tcctttctcg
      181 agcttagctt tttttcaacc cactacagtt gacaaagagc ccctttttgg ctataattat
      241 tctgcaatca aggtttccaa accaaccttc atcatatcag tgaaggtatt ttgacgttct
      301 tctgcagttg tgtcttcgtc tggattgacc aagctatcag agatggtcat gatagctagc
      361 gcatcaacat ggtattgggc agcaagatag taaagagctg ctgcttccat ttccacagcc
      421 ttgactcccc atttaccaag ctcgatattc ttttcaaagt aatttgagta aaagacatca
      481 gatgacaaaa cgttcccaac gtgagtagtc ataccaagtt ttttggcgat atggtaggct
      541 ttatcaagca aatcaaagct agcaatttgt ggaaaatcgt actgtggcca gtcattacga
      601 acgatgtttg agttggttgc agccgcctgc gccaaaacta attcacgaac atgaacctct
      661 tcattcaaag aacctgcagt tcccacacga atcaatttct tcacaccgta gtctacgatt
      721 aactcacgcg cataaatcga aatagatggc attcccatcc cagttcccat gacagataca
      781 cagtgaccct tgtaagtacc agtgtaacca aacatgttac gcacttcgtt aaaacaaaca
      841 gcatcatcaa ggaaattctc cgcaataaac ttagcacgaa gaggatcccc aggaagaaga
      901 attttatcag caatttcacc ctgctgagca gcaatatgga tagacataat ttatgataca
      961 aagagcgaga agaaaacgac tgaaaattag gaacctgacg agaaatcctg atttttcagt
     1021 cagattatct attttccgag ttttccgctc gtgttcaaat caaaacacac gctctacctt
     1081 tctttatttt atattttata ttgagaaaga taccaaaccc atcaaaaagc gaagggaaaa
     1141 taggagttgg gcgcagtgag cgatgctcgc tagatcaact atctttttcc cactactttt
     1201 agggtggggt caattccttt cttaattttg atttagagga gagtcgcccg tattcagttc
     1261 agcgaataca gtttacccat cctttcgttt ttgtttttag aaaagttttc tactcgtgtt
     1321 caaattagaa cacgcgctct acctttctgt ttatactctt cgaaaatctc ttcaaaccac
     1381 gtcaacgtcg ccttggatta tatatgtgac tgacttcgtc agtcttatct acaacctcaa
     1441 agcagtgctt tgagcaacct gcggctagtt tcttagtttg ctctttgatt ttcattgagt
     1501 attaattttg ttctttcata gagagctacc tgagtcctat tcaagctcag gtagtacttt
     1561 cttataaact agacaaacta actgtcattc taccatcaga ttacaagaca tcatcgtcac
     1621 tcaccttgga attcaatgtc gtaccccaat gggtaatttt acggtggggt tgagctaaaa
     1681 ttggtctgtt ttcatagatt gtttgccatc tattccatag taggcccgtc tttttctcaa
     1741 tcttaactcg cagatttctc atattttctt tgattgggag gttgaggaca aaacctgcag
     1801 tctggttgcg accgcttcct tcccaagaat gactacgaac aacttggttt ccatctttat
     1861 ctactggaac ttcttcccaa gttatggagt agcgggcaat gtaagctcca ctgtgttgaa
     1921 ttgtcaatgt tttatccttc acaggagtct gactgattgg ttgaactggc ttagaaactt
     1981 gtgtcgccgt ttcagcattc gtagctataa agcagaaaac ttcaacttct gcaagactga
     2041 gggcattata gccttctagc tcaatccgaa catagcgcgc ttttttatgg ttaatcgtaa
     2101 tttgtgctga cacatcttta ggagatgtta tacgttttca ctcaatttct ttaccagaac
     2161 tgtctaaaag aatgacatca aagtttgcca atctatcctg ggcagtgtct gttcggttgt
     2221 aaatattgat ttggcgaatg gtttcttctt taccaaatct acttgccacc aaggcttaga
     2281 ttggaagttt gtatgagtga cagaattgtg accatagtta ccatcgactt tgccatccac
     2341 agctcttcta gcatctcctc cgaaagctgt cgaactttga gtaacctgtt ttcctgaggc
     2401 aatattttcc attggttcag cgcttggttg actagaagat cgaggcagag cctgtttctt
     2461 aaagaatcgc actttatcca atttcggatc acgataacca tgtttatcca aggtagcttg
     2521 tttaccaata ttaaagttag gaatatcatt cattggactt tcaaaatagc cacgagaacg
     2581 gtgtttaaag cgtgaattac ctgtaaatgt aacaatatca cgattattat gaatcaaggg
     2641 agtcacaaca ttgtcattat caaccacata atgcttaatt tttccactaa cagctaattt
     2701 acgactttcc aaaccaacat cccagaaacc attcttagca ttccaaacag ttctggaagt
     2761 aatcacttta ggagcactga aagttgtcac tttcctcaat acatggttat aaaaatcagg
     2821 atatttttgg taagcttcaa ccgctgcaat ctgagctagg taacatccaa gagaatgacc
     2881 tgtcatatac aacttagtaa tacttatatc cttggctaat tccccaacaa ccttgcggat
     2941 atcatccgct tgagctggtt atgttatctc tacttttgac tcttcccttt tgttttcaag
     3001 aacttcactt gcttccggaa gcgtttgagg agctagtctt ggctcctctc taagaggagt
     3061 ttctagtttt ggagcatcat tttctgactc tttcaattcc tccttagaat ctagcacacc
     3121 tattaccact tcagatgtta catcttgctt tacttcattg gctgaaattc cagctggagc
     3181 tagaaatcaa agccgactac aacagataca actccgatac ttaatttttt atgccaaagc
     3241 gcataattcg ttgaccaatt ttcattattt cttatctttc ttttcgttta tttacaagca
     3301 gactcaagcg aaatctcatt gtgctatata tgataagact gagaaattca gaaagtcaat
     3361 tcattctcat ctctccttat catactagtc tgcttggcta ggaagctaat gctagtatcc
     3421 tagaatcttg tctttcacaa tgctggctat cagatcagac atacctattc ttccgcttct
     3481 ttcagttata agagcaggaa gaagctcata gtattcctct gtttcttctt taatccggat
     3541 aggcagtcaa tcctgaaaaa acagaggcac tccccctttt aaatcttttt tcttacaatt
     3601 cagcaagaat cgctttaagc aagcctttga aatcaccttt aacacgttca gtcacttcta
     3661 caacttcttc gtgattgagt tcttcttgga aaccggccgc aaagttagtg atacatgaaa
     3721 ttcccagaac tttcaagcca gagtgggctg ccacgataac ttcaggaacc gtagacatac
     3781 caactgcatc tgctcccagt gtcttatagg aacgaatttc tgctggtgtt tcataagtcg
     3841 gaccagtaac tccgatatag acaccttcat caagcttgat attaagtttt ttagccactt
     3901 catgggcagt ggcacggtat tctggtgtgt aggccctaga catatctggg aaacgtgggc
     3961 caaagtcatc caagttttca cccatcaatg gattttgccc cgtcatgttg atatggtctg
     4021 agatagccat caaggtacca ggaccaaatc cgataccgcc agctgcattg gttacaataa
     4081 caccttcaca tccaagaact ttcatcacac gaactgggaa agtcaccact tccagaggat
     4141 tcccttcata gaaatggaaa cgcccttgaa gagccaagac cttgcgacct gccagttcac
     4201 catataccaa tttaccagca tgaccgacta ctgttgaacg gccccagttt ggaatctcag
     4261 catagtctac tacaactgga ttttcgattt cttctgccaa ttctccaagt cctgatccaa
     4321 ggattagacc gaactcaggg gctgcaattc ccttttcttt caggaaagta gcagtttcat
     4381 ggattttgtt taaaaatgtc attgtgtgtc tcctttatta tttttttagc atttgaccaa
     4441 ttttgtcaaa ggttttagca ttacgaatag taatgtggcg gtagaaaggc accttcagca
     4501 agtacttatg ataggcagtc ttagaatagg attcttcaga aaatttcccc cagaaaatcc
     4561 caagttttcc aaaataaagc acttcatctt tcagctctaa actttcaact gtcgcgatga
     4621 cttggtccac atccaaaccc tcagtgtaaa agagaaaatc ttttcgtgcc aagtctctgc
     4681 tccaccaagc tggtagattt tcaagttccg cctcaaagtc ctctagactc agtaaagaaa
     4741 agctctgaat aaatggataa tggactgcaa agaaagtctc tagcttttca accaattggg
     4801 ctttggaatc tatcgaagta aagaaaatat tgccactatt gatgtagctc tcaacctttt
     4861 ccagtcccaa gtttgtcaat tcttgacgaa gctccgccat gacgacctta ttcttaccac
     4921 caacattgat acctctcacc agcaaagcat agcgcgtcat cttataccaa tttatctaag
     4981 aaactttccc caatcatagc agtttccaca ccaaagttat cggcaacagt cgctgaaata
     5041 tctgcaaaat gtcctactgg aatgagacca tttcctttaa aggcagggct ataggccaac
     5101 aatggaatat attcccgagt gtgatccgtt cctgcatacg ttgggtcatt tccatggtcc
     5161 gcagtaatca agagaaggtc attctctctc atagctgcga taatttcagg taagcgttca
     5221 tcaaactcat gcaagcaatc acggtaaccg tgagcattac gacgatggcc gtaaagggca
     5281 tcaaagtcaa ctaggtttgt gaatgagaat cctttttcaa actcagcaag tcccatagtc
     5341 ttcaatagtg tatcaattcc atgactattt gacttgttgt gacccatgtc atggttgata
     5401 ccagcaccgt taaagatatc gttgatttta cccacagcat aagtatcgat accagcctca
     5461 ttcaatttat ccaaaacagt tggggaaaat ggagatacag ccaagtcacg acggtttgcc
     5521 gtacgagtga agttacctgg ttcacctaca taagggcgag caatgatgcg accaagaagg
     5581 gcaggacgct caagggtaat cgaacgagcg tattcacaga tacggtacaa ttcatccaaa
     5641 ggaataatgt cttcgtgggc agcaatctgc aaaacagggt cagctgaagt atagataatc
     5701 aactctccag tttccatctg acgtggtcca aaatcataga taacagccgt tcctgaataa
     5761 ggtttgttgg cttcacgaat aaccttgcgt cctgagaatt cttcgatttt tgtcaggatt
     5821 tcttctggga atccgttcca gaaagtatcg aaaggctcag taatgttgag tcccatgatt
     5881 tcccagtgtc cagtcatagt atccttacca agagatactt cctctaattt tgttgcatat
     5941 ccagttggat tgctttcagc tgctacagtc ttaagaggag tttcacgagg aatatttcca
     6001 agacctattt tagccatgtt tgggacattc aaaccaactg tttttgaaat gtgtcccagt
     6061 gtgtcagaag ctccatctgg aacccctgca ttgacaaagt tattagcatc tggtgctgca
     6121 ccgattccta cagaatccag taccaccaaa tgaatacgat taaatttaga catcttatgc
     6181 ccccttctat tttccttttt ttgaagttga aatctgaact ccatctcgtc cagcaacgat
     6241 taccttatcc accatttggt tgaataaacc atgctccaca acaccaacga catggtccaa
     6301 ttcttgtcca aaagcaattg gattttcaat gacatccaag gcgaggtcaa tgataaaatt
     6361 ctgcatatcc gtcacaaaac gttggccgtc tttttcacgg aaacttggtt tgtagccagc
     6421 tcgttcaaaa tgacgaaaga cctgctctgc accatactga accacttcta ctggcaattt
     6481 aaaagcacct agtttttcga ccagcttgct ttcatccacc acccaaatgt attcttttga
     6541 tggtgttgcg accacctttt ccatgagaag ggcaccacca ccgcctttga ttccattaaa
     6601 ctgactatcc acttcatccg cgccatcaac cgtcacatcg acaaaatcta cttggtcaat
     6661 agacttgagc gggatattaa ggccttctgc ctgtttagtg gtcacactag aagttgttac
     6721 agctgtaatc tgcaatcctt cttccttgat acgacgaccg atttcttcga caaaataata
     6781 ggcagtcgag cctgttccaa gtccaacgac cattccatcg ctcacgaact cagcagcctt
     6841 gatacctgcc attttcttca gattttccac cgatttacct ccatcattct cagttcttat
     6901 tttactatga aaccgctttt tattcaagta aaaacatcaa atctacattt ttcatcaatc
     6961 tttctttaaa aatatgcatt ttatttttac caaacgaata aaaatgagtt tatcttttat
     7021 gtatttgatt tgttcatctc tttccagtta caaaaacaaa ctcttaactt tgatacgtct
     7081 agtttagcct taaagcaggc gcatttcaag aatcataaat taagagaagg aagtagattt
     7141 atctgtctat tttaaacaag tttatctttg cttaccctct cttgttgaca aataattttc
     7201 attattttgg gaagatacct gctgatttcc gtcggtaaga ccacataatt ttcttgagat
     7261 agttcttggg ctatggctga atgaagatgg gtcgctactg ccacacgctc gtagagactg
     7321 gcctgtcgga attggcctac aaatcctgcg atcatcccag ccagagtagc tcccattccc
     7381 ccagtcgcct gataaggacc accaacctgt aactggtaat aatcagattg gccaacttcc
     7441 caaatacgag tagctgggcc tttctccacc aaaattgttc cttgagggaa ggaagtcaga
     7501 acactagccg ttgcatcttc cttttgcttt tcaatcgtaa ttccagataa tttttcccat
     7561 tctttttggt gaggagttag gataagctgg cttgagggaa atgacaaact tgtcctagca
     7621 agaatggtca aggcacctcc gtctacaatc aaaatctgat tttggcttaa attaacaaag
     7681 acctgtttta ctagattttc tccagaagca tcgtctcgta aaccaggccc cagcaagaca
     7741 acttctgcct tctccaattg ctcttttaac aattgctggt cttgaagaga aaaggccata
     7801 ggctcaggta aatggctgtg cagagccggg atattttccc tgtccgttcc aacggtcacc
     7861 aatcctgcac cgctttttac agctgctaaa gcagccatga tgatggcacc tccataagga
     7921 taagtaccac caagcagcag cagacgacca taatctcctt tatgacttga acgagaacgt
     7981 tcaataataa ctttttctaa taaggtttga ttaatcactt tcatcctttt ttcctctcac
     8041 ttttattata caataaaaag gagacgcaga cctccttttg taatcttata tctaaaattt
     8101 aatattcatt tctgccattt tagatatagc tatagaaaat acactctatt aatcgaatgt
     8161 ttctcttatt ttctatccaa tgtccgaagt gctgcttgat aagtttgctc catcagcatg
     8221 gtaatggtca taggaccgac acctccaggg actggcgtga tatggctagc aagtggtgca
     8281 actgcctcat aatcaacatc tccacagagc ttcccatttt catctcgatt catcccaacg
     8341 tcaatgacaa ccgcacctgg tttgacaaag tcagcagtca caaacttggc gcggccgatt
     8401 gcgactacaa gaatatctgc tttagcagcc accttggcaa gattatgagt tcgtgagtgg
     8461 gtcaaggtta ctgtcgcatt tttagccaaa agaagctgag ccataggttt tccaacgata
     8521 tttgaacgac cgatgacgac cgcattttta ccttccaagt caatcccata ttcatgaaac
     8581 atttccataa ttcctgcagg tgtcgaggga atcatgactg gatgtccaga ccaaagacgt
     8641 cccatgttta ggggatggaa accatccaca tccttttctg gatcaatggc taataaaacc
     8701 gcctcttcat cgatatgttt tggtaatggc aactggacca aaatcccatg ccaagctgga
     8761 tcctgattat atttagcaat caggtctaac aattcctctt gagtaatggt ctctggaact
     8821 cgcactactt cgctacggga accagccgca agagctgacc tctccttgtt gcgaacgtag
     8881 acttggctgg ctggattatc cccaaccaaa atcactacca aaccaggcac tagacctgtt
     8941 tcttccttta attttgcagt cttttcagcc aactgcccct gcaatttggc cgctaaagct
     9001 ttcccatcaa taatctgtgt catatcactt ctcttttctt tcaaatatct tccattatac
     9061 caaaaactgc tagtgccctc taacacttct ttcctaggtt atcctatagt ttcaaactat
     9121 aagaaaaagc tctggttgaa cttttcacta atcttgtctt gaaattttaa aatagattat
     9181 aaaaccttac tcaagaaatc tttagtccgt tgttcttggg tttgttcaaa aatctgctca
     9241 ggtgtcccat cttcaacaac cacaccgtct gccataaaga taacacgatc tgccacctca
     9301 cgggcaaatc ccatctcatg tgttacgata accatagtca tccctgactt ggcaaggtct
     9361 tgcataacag ccaatacctc acctaccatt tcaggatcca aggctgaagt tggttcgtca
     9421 aagagcaaaa catctggttc catagccaac ccacgcgcga tggcaatccg ttgttgttgc
     9481 ccacccgaca gactctgtgg ataagcgtct gccttatctg gcaaaccaac tttttccaaa
     9541 agctcttggg ctctcttctc agcaacttcc ctgctttcac ctttagtctt gataggtgac
     9601 aaggtaatat tttccatcac agtcatatta ggaaagaggt taaactgttg gaaaaccatg
     9661 cccatcttct cacgcatggc aaacaagtca ttcttcttgt ccgtaatatc gactccctca
     9721 aagataagct tccccttggt tgcttcctcc aacaaattca tagagcgaag caaggtagat
     9781 ttcccactcc ctgaaggacc gatgataacg acaacttctc ctcttttaat ctcgaggttg
     9841 attcccttca atacttcatt ctttccaaaa gatttatgta aattttcaat ttttatcaag
     9901 gtttctgtca ttatttctta tctccttgtc ccatatgttt ttcaaaagct ttcaaggcta
     9961 ctgtcagaat agaggtcata atcaagtaat aaaatgctgc aaataaaagc ggtgttaaag
    10021 gtagataggt tgttgtagaa actgttgtag ccccattcca caactccatg accccaatag
    10081 ctgataagag ggagctgtcc ttgataatgg tgataaattc gttccccaat gctggcaaga
    10141 tatttttgat tgcttgtggc aaaatcacat aacgcatcgc atttttagga cgaatcccta
    10201 gcgaataagc cgcctctagc tgaccttttg gaaccgcatt gattccggca cgaacagtct
    10261 ccgaaacata agcaccacta ttcatagaga taatcaaaat ccctggaatc agacgcgaaa
    10321 aatcaacacc taaaattcca atctgaatag tcggagcatt gatatgcata agagcaaagg
    10381 caatcataat ttgaaccatc atcggtgtcc cacggaaaat ccaaacgtac aagttggcca
    10441 accaaacaag cggtttaaac tttgaacgtt gcccaaaagc caagacaaca cccaaaatag
    10501 ttcccaaaaa gataacacag atagaaataa gaatcgtcac aacagcccca tagttaaaat
    10561 aaggtaaata cttaggtaaa aaagaaaaat tcatagtcac actgctttct aaaatagaat
    10621 actgtatgat tataacatgt tttgaattaa aatttaaatt ttttatccaa tttatttaaa
    10681 aatctttaaa ctagcagaat tagcgagaaa tcttagtttt ttctagtcaa gttggcctcc
    10741 tttatggtaa aatagtaacg ataagaaatg aaggagaatc aaaatggaat cacatttggt
    10801 tagaatcatc aaccgccttg aagcaatggc aaacgatggc ggaaatttaa aacgtaattt
    10861 tgaacgcgaa ggagttgttg ttgcagaagt tgcgtacagc cacgacgaag aaaacggccc
    10921 aatctttacc cttcgtgacg tagaagatcg cgaaacgtat acgtttgata gcattgactt
    10981 aatcgcaatg gaaatttacg aacttctcta ctaatctaaa acaagctggg attgtccctg
    11041 tatgtctaag taaaatcctt tttgtctcac aaataggatt tttttatagt ccaaattcac
    11101 aaaaattttc attgtaacaa cttctcaaag cttcaatctt tttacttgct ttacacccca
    11161 atcctgttat aatgagagta tagaatttga ctatttttga cctttaaaca agtcaggcta
    11221 aagaaagaaa tgaggtagat gtatgctttg tcaaaactgt aaaattaacg actcaacaat
    11281 tcatctttac accaatctca atggaaaaca aaaacaaatt gacctctgtc aaaactgcta
    11341 taagattatc aaaacagatc ctaacaatag cctcttcaaa ggtatgacgg atctgaacaa
    11401 tcgtgacttc gatccctttg gtgatttctt caatgatcta aacaatttca gaccttctag
    11461 caatactcct cctattcccc caacccaatc aggtggaggt tacggtggaa acggcggtta
    11521 tggttcccaa aatcgtggat ctgctcaaac tccgccacct agccaagaaa aaggcctgct
    11581 ggaagaattt ggtattaatg taactgaaat tgcccgtcgt ggagacattg accccgttat
    11641 tgggcgcgac gatgagatta tccgtgtcat cgagattctc aatcgtagaa ccaagaataa
    11701 tcctgtcctt atcggtgaac ctggtgtcgg aaaaacggcc gttgtcgaag gtctagctca
    11761 gaaaattgtc gatggcgatg tgccacataa actccaaggt aaacaagtca tccgtctgga
    11821 tgtggttagc ttagttcaag gaacggggat tcgaggacaa tttgaagaac gcatgcaaaa
    11881 actcatggaa gaaattcgca aacgtgaaga catcatcctc tttatcgatg aaatccatga
    11941 aattgttggt gctggttctg cgagtgatgg taatatggac gcaggaaata tcctcaagcc
    12001 agcccttgct cgtggagaac tgcaactagt cggtgctact accctcaatg aataccgtat
    12061 cattgaaaag gatgctgccc tcgagcgtcg tatgcagcct gttaaagtcg atgaaccaac
    12121 ggtggacgaa acaatcacta ttctcaaagg gattcaaaag aaatacgaag attaccacca
    12181 cgttcaatat acagatgctg cgattgaagc agctgcaact ctttccaatc gctacatcca
    12241 agatcgcttc ttgcctgaca aggccattga cctcctagat gaagctggtt ctaagatgaa
    12301 cttgaccttg aattttgtgg atcctaaagt aattgatcag cgcttgattg aggctgaaaa
    12361 tctcaagtct caagctacac gagaagaaga ttttgagaag gcggcctact tccgcgacca
    12421 gattgccaag tataaggaaa tgcaaaagaa aaagatcaca gaccagaata ctcctatcat
    12481 cagcgagaaa actattgagc acattatcga gcagaaaacc aatatccctg ttggtgattt
    12541 gaaagagaaa gaacaatctc aactcatcca tctagccgaa gatctcaagt ctcatgttat
    12601 tggccaagat gatgcagtcg ataagattgc caaggctatt cgccgtaatc gtgtcggact
    12661 tggtacccct aaccgcccaa tcggaagctt cctcttcgtt gggccaactg gtgtcggtaa
    12721 gacagaactt tccaaacaac tggctatcga actttttggt tctgctgata gtatgattcg
    12781 ctttgatatg agtgaataca tggaaaaaca tagtgtggct aagttggtcg gcgctcctcc
    12841 aggttatgtt ggctatgatg aggctggtca attaactgaa aaagttcgcc acaatccata
    12901 ttctctcatc cttctcgatg aagtggaaaa agctcaccca gatgttatgc acatgtttct
    12961 tcaagtcttg gacgatggtc gtttgacaga cgggcaagga cgcaccgtta gcttcaagga
    13021 tgctatcatt atcatgacct caaatgcagg tacaggaaag accgaagcta gcgttggatt
    13081 tggtgctgct agagaaggac gtaccaattc tgtcctcggt gaactcggta acttctttag
    13141 cccagagttt atgaaccgtt ttgatggcat tatcgaattt aaggctctca gcaaggataa
    13201 cctccttcag attgtcgagc tcatgctagc agatgttaac aagcgcctct ctagcaacaa
    13261 cattcgtttg gatgtaactg ataaggtcaa ggaaaagttg gttgacctag gttatgatcc
    13321 aaaaatggga gcacgcccac ttcgtcggac tattcaagac tatattgagg acacaatcac
    13381 tgactactac cttgaaaatc caagcgaaaa agatctcaaa gcagttatga ctagcaaggg
    13441 aaacattcag attaaatctg ccaaaaaaac tgaagttaaa agttctgaaa aagaaaaata
    13501 aatcctataa aaaaagagta gaaaatgaaa tttttctgct tcttttttta ctaaaataac
    13561 tgtaatttct tgacagcttg ccctttgtcc attatgat
//
LOCUS       DAVLHB010000052        13403 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLHB010000052 DAVLHB010000000
VERSION     DAVLHB010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.052"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            148..804
                     /locus_tag="VXE36_001745"
     CDS             148..804
                     /locus_tag="VXE36_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0779998.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            794..1117
                     /locus_tag="VXE36_001746"
     CDS             794..1117
                     /locus_tag="VXE36_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0779999.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFCYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1221..2051
                     /locus_tag="VXE36_001747"
     CDS             1221..2051
                     /locus_tag="VXE36_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0780000.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTGNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2205..3059
                     /locus_tag="VXE36_001748"
     CDS             2205..3059
                     /locus_tag="VXE36_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0780001.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3159..4532
                     /locus_tag="VXE36_001749"
     CDS             3159..4532
                     /locus_tag="VXE36_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0780002.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDTKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFDPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4525..5586
                     /locus_tag="VXE36_001750"
     CDS             4525..5586
                     /locus_tag="VXE36_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0780003.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5588..6280
                     /locus_tag="VXE36_001751"
     CDS             5588..6280
                     /locus_tag="VXE36_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0780004.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6310..6879)
                     /locus_tag="VXE36_001752"
     CDS             complement(6310..6879)
                     /locus_tag="VXE36_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0780005.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPTPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7014..7628
                     /locus_tag="VXE36_001753"
     CDS             7014..7628
                     /locus_tag="VXE36_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0780006.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7630..9276
                     /locus_tag="VXE36_001754"
     CDS             7630..9276
                     /locus_tag="VXE36_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0780007.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9288..10574
                     /locus_tag="VXE36_001755"
     CDS             9288..10574
                     /locus_tag="VXE36_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0780008.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGHPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFDQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10626..11159
                     /locus_tag="VXE36_001756"
     CDS             10626..11159
                     /locus_tag="VXE36_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0780009.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11237..11707
                     /gene="nrdI"
                     /locus_tag="VXE36_001757"
     CDS             11237..11707
                     /gene="nrdI"
                     /locus_tag="VXE36_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0780010.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12000..13262)
                     /locus_tag="VXE36_001758"
     CDS             complement(12000..13262)
                     /locus_tag="VXE36_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0780011.1"
                     /translation="MSQAITLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3920 a         2506 c         3081 g         3896 t
ORIGIN      
        1 tcagttctat ctgcaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt
       61 tgctctttga ttttcattga gtattattaa gacaatatga ggagaaagat gaaagaaaaa
      121 ggattttagg agggggcgca ggcagccatg ccaacggctc ttggctatgt cagtatcggc
      181 ctggcctgtg ggactatcgg tgcgccctat gtgacacctg ttgagatggg cttgatgagt
      241 ctctttgttt atgctgggag tgcccagttt gccatgttgg cactgattgt ggttcaagct
      301 cctgtggcag ctattgctat gacggttttt ctaatcaact tgcgtctctt tttgttgagt
      361 ttacacgcat cgacttattt ccgtcatacc agtctttggt acaatatcgg tatgtctagt
      421 atcttgacag atgagaccta tggcgttttg atgggtgaat tggcccatac agacaaggta
      481 aatcctatgt ggatgcacgg aaacaatctt aacagctatg tggcttggtt tgtggggaca
      541 gtagtcggaa cggctctggg tggcctgcta ccaaatccag aaatctttgg cttggatttt
      601 gccctggttg ggatgtttat tggtattttt gcttcgcaat ttcagattat gcaaagacgg
      661 attcctgtcc gcaatctgct cattatccta gcagttgttg cggtgtcctt ctttttgctc
      721 ttgacagtgg tgtctcagtc actagctgtt ctgtttgcga cgctacttgg ttgtagcatg
      781 ggggtggttt tagatggtca gtaagtatct tttattagca gttattttct ctggcttggt
      841 gacttggatt ctccgtatga ttcccttcat cttagtcaag tataagggct tgcctgcaat
      901 cgttgagcgt tttttgaagt tcttgcccgt ttccattatc tttgccttga ttctttcaag
      961 cgtagtgaca ggtaaggttg ggagccttcc tcaaattaaa tggctagact tcttagccgt
     1021 ctttccaaca gcttgggtag ccttttgcta ccgcaatcta gtcggaacag ttctctttgg
     1081 agtggtcttg attgccatct tgcgtttggt cttttaaatt acccataaaa aaaacttatc
     1141 acagagatag atatcatata atggcgtaaa tgctcttttt ctgttaagat tataaggtat
     1201 tctattttgg aggaaatgac atgaaaaaaa tcgttaaata ctcatctctt gctgccctag
     1261 gacttgttgc tgcaggtgtg cttgcggctt gctcaggtgg tgctaagaaa gaaggacaag
     1321 cagctagcaa gaaagaaatc atcgttgcaa ccaatggatc accaaggcca tttatctatg
     1381 aagaaaatgg cgaattgact ggttacgaga ttgaagtcgt tcgcgctatc tttaaagatt
     1441 ctgacaaata tgatgtcaag tttgaaaaga cagaatggtc aggtgtcttt gctggtcttg
     1501 acgctgaccg ttacaatatg gctgtcaaca atcttagcta cactaaagaa cgtgcggaga
     1561 aatacctcta tgccgcacca attgcccaaa atcctaatgt ccttgtcgtg aagaaagatg
     1621 actctagtat caagtctctc gatgatatcg gtggaaaatc gacggaagtc gttcaagcca
     1681 ctacatcagc taagcagtta gaagcataca atgctgaaca cacgggcaac ccaactatcc
     1741 ttaactatac taaggcagac ttccaacaaa tcatggtacg tttgagcgat ggacaatttg
     1801 actataagat ttttgataaa atcggtgttg aaacagtgat caagaaccaa ggtttggaca
     1861 acttgaaagt tatcgaactt ccaagcgacc aacaaccgta cgtttaccca cttcttgctc
     1921 agggtcaaga tgagttgaaa tcatttgtag acaaacgcat taaagaactc tacaaagacg
     1981 gaacgcttga aaaattgtct aaacaattct tcggagatac ttatctacca gcagaggctg
     2041 atattaaata atttcttgaa atcatccatt ctgagtaaga tgggtgattt ctcagttttt
     2101 agggatatag ttttaaacta tatatctgat tatctaataa caatttgtga aatcaaacaa
     2161 attgtgagat actagtacgg tattattttt aaggagaaag aatcatgaaa atcaaaaaat
     2221 ggcttggcct agcagccctt gctacagtcg caggtttggc tcttgcagct tgcggaaact
     2281 cagaaaagaa agcagacaat gcaacaacta tcaaaatcgc aactgttaac cgtagcggtt
     2341 ctgaagaaaa acgttgggac aaaatccaag aattggttaa aaaagacgga attaccttgg
     2401 aatttacaga gttcacagac tactcacaac caaacaaagc aactgctgat ggcgaagtag
     2461 atttgaacgc tttccaacac tataacttct tgaacaactg gaacaaagaa aacggaaaag
     2521 accttgtagc gattgcagat acttacatct ctccaatccg cctttactca ggtttgaatg
     2581 gaagtgccaa caagtacact aaagtagaag acatcccagc aaacggagaa atcgctgtac
     2641 cgaatgacgc tacaaacgaa agccgtgcgc tttatttgct tcaatcagct ggcttgatta
     2701 aattggatgt ttctggaact gctcttgcaa cagttgccaa catcaaagaa aatccaaaga
     2761 acttgaaaat cactgaattg gacgctagcc aaacagctcg ttcattgtca tcagttgacg
     2821 ctgccgttgt aaacaatacc ttcgttacag aagcaaaatt ggactacaag aaagcacttt
     2881 tcaaagaaca agctgatgaa aactcaaaac aatggtacaa catcattgtt gcaaaaaaag
     2941 attgggaaac atcacctaag gctgatgcta tcaagaaagt aatcgcagct taccacacag
     3001 atgacgtgaa aaaagttatc gaagaatcat cagatggttt ggatcaacca gtttggtaat
     3061 aagaaacagg gaggtgggag agaaaattcc acctcttgct tttgtataga gtatagattg
     3121 taaagaagac tattcgttca tagaaaggta gagagaatat ggtttttcct agcgaacaag
     3181 aacagattga aaaatttgaa aaggatcatg tagtccaaca ttattttgag gttttgcgta
     3241 ccttgatttc taagaaatca gtctttgccc agcaggttgg actcaaggaa gtcgcaaatt
     3301 atctgggtga gattttcaag cgtgttggag ctgaagtgga gattgatgag agctatacag
     3361 cgccctttgt catggcacat ttcaagagtt cgcgtccaga taccaagacc ttgattttct
     3421 ataaccacta tgacactgtg ccagcggatg gggatcaggt ctggacagag gatcctttta
     3481 cgctttcggt ccgcaatggc ttcatgtatg ggcgtggggt tgatgacgac aagggtcata
     3541 tcacagctcg cttgagtgct ttgagaaaat atatgcagca ccatgatgat ttacctgtca
     3601 atatcagctt tatcatggag ggagcggagg aatcggcttc aacagaccta gataagtatt
     3661 tggaaaagca tgcagacaaa ctccgtgggg cggatttgtt ggtctgggaa caagggacca
     3721 aaaatgcctt ggaacagctg gaaatttctg gtggcaataa ggggattgtg acctttgatg
     3781 ccaaggtaaa aagcgctgat gtggatatcc actcgagtta tggtggtgtt gtggaatcag
     3841 ctccttggta tctcctccaa gccttacagt ctcttcgtgc tgcggatggc cgtatcttgg
     3901 ttgaaggctt gtacgaagaa gtacaagagc ccaatgaacg agaaatggcc ttgctagaaa
     3961 cttatggtca acgaaaccca gaggaagtta gtcggattta tggattggag ttgcctctct
     4021 tacaggagga gcggatggcc tttctaaaac gtttcttttt cgatccagcg cttaatatcg
     4081 aaggaatcca gtctggttat caaggtcagg gtgttaagac tattttacct gcagaagcca
     4141 gtgccaagct agaggttcgt ctggttccgg gcctagaacc gcatgatgtt ctggaaaaaa
     4201 ttcggaaaca gctagacaaa aatggctttg ataaggtaga attatactat accttgggag
     4261 agatgagcta tcgaagcgat atgagcgcac cagccattct caatgtgatc gagttggcca
     4321 agaaattcta tccacagggc gtttcagtct tgccgacgac agcggggaca ggacctatgc
     4381 atacggtctt tgatgcccta gaggtaccaa tggttgcatt cggtctagga aatgccaata
     4441 gccgagacca cggtggagat gaaaatgtgc gaatcgctga ttattacacc catatcgaat
     4501 tagtagagga gctgattaga agctatgagt agagatatta tcaagttaga tcagatcgat
     4561 gtgacttttc accaaaagaa gagaaccatc acagcggtta aggatgtgac cattcacatc
     4621 caagaagggg atatctacgg aatcgttgga tattctggag caggaaaatc aacccttgta
     4681 cgggtgatta atctcttgca aaaaccatct gcagggaaaa ttaccattga cgatgatgtg
     4741 atttttgacg gcaaggtgac cttgacggca gagcagttgc gtcgtaaacg tcaagatatc
     4801 ggaatgattt tccagcattt taacctgatg agccaaaaga cagcagagga gaatgtagcc
     4861 tttgccctta aacactctga actcagcaag gaagaaaaga aggctaaagt agctaagttg
     4921 ttggacttgg ttggtttggc agatcgtgct gaaaactacc cttcacaact atctggaggg
     4981 caaaaacagc gtgtggccat tgcgcgtgcc ttggccaatg atccaaaaat cttgatttca
     5041 gacgagtcaa cttctgccct tgatccgaag acaaccaagc agattttggc cttgttgcaa
     5101 gatttgaacc aaaaattagg cttgactgtt gtcttgatta cgcatgaaat gcagattgtc
     5161 aaagacattg ccaaccgtgt ggcggttatg caggatgggc atttgattga agagggtagt
     5221 gtgcttgaaa tcttctcaga ccctaaacaa cctttgactc aagactttat ctcaacagct
     5281 acaggtattg acgaagccat ggtcaaaatc gagaagcaag aaatcgtgga acacttgtct
     5341 gaaaacagtc tcttggtgca actcaagtac gctggagctt caacagacga gccacttttg
     5401 aatgaattgt acaagcatta ccaagtaatg gctaatattc tctatgggaa tatcgaaatt
     5461 ctcgatggta ctcctgttgg agaattggtg gtggtcttgt caggtgaaaa agcagcgttg
     5521 gcaggtgccc aagaagccat tcgtcaagca ggtgtacaac taaaagtatt gaagggagta
     5581 cagtaagatg gaatcattga ttcaaaccta tttaccaaat gtctataaaa tgggttgggc
     5641 tggtcaggca ggctggggaa cggctatcta cttaactctt tatatgacag ttctttcctt
     5701 cattatcgga ggcttcttgg ggctagtggc aggtctcttt ctcgtcttga cagcgccagg
     5761 tggtgtcttg gagaataaag tcgtattctg gattttagac aaaattacct caatttttcg
     5821 tgcggttccc tttatcatcc tcttggcaat cttgtcacca ctttctcact tgattgttaa
     5881 aacaagtatc gggccaaatg cagcccttgt cccactttct tttgcagtct ttgccttctt
     5941 tgcccgtcag gtgcaggttg tcttggctga attggatggc ggtgtcattg aggcggctca
     6001 agcgagcgga gcgactttct gggacatcgt gggtgtttac ctatcagaag gtcttccaga
     6061 tttgatccgt gtgacgactg tgaccttgat ttcccttgtt ggggaaacag ctatggccgg
     6121 tgcggttgga gctggtggta tcggtaacgt agccatcgct tatggattta accgctacaa
     6181 tcacgatgtg accatcttgg caaccattat tatcattttg attatctttg caatccaatt
     6241 cttgggagat ttcttgacta agaaattgag ccataaataa aaaagagccg cgtggctctt
     6301 tttaactgat cagattttct gtgcaaattt tttactcaag gcttgtccaa tcaaggcacc
     6361 cactagggct ccgatgacaa tacttgcgat aaatagaagg acagttccag gggttggagc
     6421 gaccatgata cggtcgatat attcttggga ttttcctctt gccagaagag tagccatata
     6481 ggctttgggc gcaatccaca taagcaagat tggtcctgtt gtactaaagg cgaaaataat
     6541 gaaagaaagg aagttctttg ttttgtcctt gtattttcct aaatgagcta cttcatctgc
     6601 taggaggcca cagataattc caggaaggaa ggaaccagca ccgtgtttag ttcccaagaa
     6661 aaagaaggca atgacaaggc cgatagtggt aatggctcca aagcgcggaa cttttgcgac
     6721 taggatcata tagacgctac cgccgacaag ggcagtaaag gcaggcgcat aaaacatgtt
     6781 tccagtttgg tcaaagagat tgcccaaaag gacaccaatc cccatgcaga ggaagtaaag
     6841 aactgcaaaa agcagtgtag ttaagataga tttcttcatg aattgtctcc tgataatttt
     6901 ttcacaattc tcattttacc atggtttggt gggattgtaa atggatacta gaagtttttg
     6961 aaaacgcttg aaatatgata taatggtttc atagttattt ttaggggaat atcatgggta
     7021 gatttttaga ctttgtcttt aatcgtttct ttttagggat gattgcgaca gccttctttt
     7081 ggctattaac tttagcagga gggattatcc ttggtctagc gccggctagt gccaccttga
     7141 tgagcttata tgcagaacat ggttatagct ttcgggaata cagtttgaag gaggcttggt
     7201 ctctttacaa gcaaaatttt gtctcaagca acctgatttt ctatagcttt ttaggtgtgg
     7261 gtctagtttt gacctatggt ttgtatctct tggtgcaatt gcctcatcag accattgttc
     7321 atttgattgc gacccttttg aatgtcctag tagttgccct gatctttttg gcttatacag
     7381 tatctttaaa attacaagtt tattttgcct tgtcctatcg aaatagtctc aaattatcct
     7441 tgattggcat ctttatgagt ctagcagctg tggccaaggt tctccttggg actgtgctac
     7501 ttgtagcaat tggttactat atgcctgccc tgctattttt tgtaggaatt gggatgtggc
     7561 atttctttat cagtgatatg ttggaacctg tctatgaaat catccatgaa aaattggcga
     7621 caaaatagaa tgaagcagtt ttggctacat acgcttctaa gaacctatag ttcagtgatg
     7681 atcattatca ttgcgagttt tgcaatctta ctctcttacg ctgactggga ttcacgtgaa
     7741 aaggaagccc agagagtagc ccagcgtgta actgctagaa cagtgagtga aattgaatat
     7801 taccatagag agtcaaccca gatagctcag gctttagttg aaaatcaagc tcgtatcgag
     7861 ggaatctata aatactttag ccttagcatg ccagactatt tttactggca attagagcgg
     7921 aaagcttcgc cttatatatc agtctctctg tatgaaaatg ttgatgacct ctatgttcga
     7981 aatgattttg taactggggt ggccattgct tttcaagatt acaaggaagt ctatgtttct
     8041 actaaagaca aacgtagtgg agaaaaaatc agggctgagg atttcaaacc agcaggaaat
     8101 agttttgcca ttccagtgtc agatccagtg tcagatcaag acttaggagt gatttacatc
     8161 tccttggatc ctgctgtttt ataccatgcc attgataata ctagaggtca tactccgatg
     8221 gcagtaacag tgacctcacc ttttgatacg gagatttttc atatgggtga gacagttgat
     8281 aaggagagtg aaaattggct agttggctta acttctcatg gttatcaggt tcaggtggca
     8341 gttcccaaaa actttgtttt acaaggaacg gtgaccagct ctgctttgat tgtgggcttg
     8401 agccttctct ttattgtcat tctttatctg actttgaggc agacctttgc taattatcaa
     8461 aagcaggtag tggatttggt ggattccatc caagctattg cccaaggaca agaaggtctt
     8521 cgcattgata cgcttgaaaa ggatcaggaa ttgctcctaa tcgcggagac gaccaatgat
     8581 atgttggatc gattggaaaa gaatatccat gatatttacc agttagaact cagtcaaaaa
     8641 gatgccaata tgcgggcctt gcaggcgcaa atcaatcctc acttcatgta taatacgctg
     8701 gagttcttgc gtatgtacgc agtcatgcag agtcaagatg agttggcaga tatcatttat
     8761 gaattcagta gtctcttgcg taacaatatt tccgacgaaa gagagaccct cctcaaacag
     8821 gaattagaat tttgccgtaa atacagctat ctctgcatgg ttcgctatcc caagtccatt
     8881 gcctatggtt tcaagataga tccagagtta gagaatatga agattcccaa gtttaccttg
     8941 caaccgctgg tagaaaacta tttcgcgcat ggtgttgacc acaggcggac agataatgtg
     9001 attagcatca aggctcttaa acaggatggg tttgtggaaa ttttggtggt cgataatggt
     9061 agaggaatgt cggctgaaaa gttggcaaat atccgagaaa aattaagtca gaaatatttt
     9121 gaacaccaag ccagctacag tgatcaaagg cagtctatcg ggattgtcaa tgtacacgag
     9181 cgttttgtgc tctattttgg agaccgctat gccattacta tagagtctgc agagcaagcc
     9241 ggtgttcagt atcgtattac aattcaagat gagtagaaag ggagaaaatg tataaagtgt
     9301 tattagtaga tgatgagtac atggtgacag aaggtctgaa gcgtttgatt ccctttgata
     9361 agtgggatat ggaggtcgtc gcaacagcca gtcatgccga tgaagctcta gaatatgttc
     9421 aggaaaatcc tgtcgatgtc atcatttccg atgtcaatat gccagacaaa acagggcttg
     9481 atatgattcg ggagatgaaa gagatcttac cagatgctgc ctatatcctg ctctcaggtt
     9541 atcaggagtt tgattatgta aaaagagcaa tgaaccttag tgtggtggac tatttggtca
     9601 agcctgttga taaggtagag ctgggaaatc tgctggagaa gattgcaggt cagctcggcg
     9661 agagagggaa gaaaagtcag actcttagtc aagaattaga cgaggctgga tttgttagtt
     9721 atttagggga taaggagaat tggtggatag gtctatccaa ggaaaaacaa ggttccttca
     9781 ccattcccta ctatgtcttg ggtcaagact ggcagatttt catttctggc caccccctag
     9841 atggtttagt cgttacacct tttgaagctc cttatcaaga acattttgaa cgctggaagc
     9901 tgaatgctga gaaaaccctc ttttacggtt ctgtaaatct gcagcagtct gagagtctct
     9961 ttgcctatta cgaaccgatt tatagggtta tcattcaggg aaatctcaat caaatcgtag
    10021 aagagttaaa tctcttggag aaggtagttc ttgaaaatac acctcgtgtt tcgattacta
    10081 aacagctttt tatccagttt gtcatggatg ttttccattt atttgaacat ctcaaagctg
    10141 atgatatgac ggacattgtc aaaaccattc atgctattca atccttcgat gaattggttt
    10201 cttatatcaa ggaaactctg atcagctttt tcgatcaata ccgtatgaat gaaaatgtgg
    10261 tcagtgtgct ggaagtcatt ggtcgtgatt accaaaaaga gctttccctc aaggatatca
    10321 gtaaggccct ctttatcaat cctgtctatc tagggcagtt gattaagcgt gaaaccgatt
    10381 cgacctttgc agagttacta aataaacaac gtattaaggc tgcccagcag ctcttgcttt
    10441 caactagtga cagcatcgaa gatatttgtt atgctgttgg ttacagtaac cttggatatt
    10501 tctataaagt tttccgaaaa ttgtgcggaa aatcgccaaa agcctaccga aaacaggtag
    10561 aaactatact ataagatttg tattccttta caaaaggtgc tataatatta tcaggaggtc
    10621 ctatcatgaa aaagaaacca atttatctat gggttttgct aatcttgtct gcccttattt
    10681 cagttccgtc tctgtttgga attgtgagtc ccttgcctag taaagaagcc cttcgtgctg
    10741 ctcagaaaca agttgcaggg gtcaatgctc agcaattaga agaccagctt aattatacct
    10801 atagagtagc agaagcatct cattctattt ttaatgttgc tttgattgtg ctatctacta
    10861 ttttagtggt cgtagcgatt gtcttccttg ttcgtaaaaa tttgcaatat gcaaactata
    10921 cttacgttgg ctatgttttg ttagctatta ttggttcgat ttatggctat gttggtttac
    10981 aagacgctgt gcagttggtt caagatgaga gcatgcgttt gacagtgagt attggttcaa
    11041 aagctgttag cattttctat atcgtcatca atgttctctt cctagccctt gtcttctata
    11101 agatgtggcg acaacagaaa gccttggcag aagaagagga aacagaagag cttacctaag
    11161 tattgacaaa aaagaactat caagatacaa tcttggtagt tgttttttga ttatagataa
    11221 aatcatggag gtacatatga agacaatttc tttagtttat attagtttga gtggcaacac
    11281 tgaaagtttt gtgacgcgct tgaaagacta tctcttgtcc cagtacaaag ggattgaggt
    11341 tcaaaagatt catatcaagg atttggtcaa ggaaggcaaa aatttctatg aaatggacca
    11401 tccctatgtc gcttttttgc cgacctatct cgaaggtggg aatggcgtgg ataacggaga
    11461 tgttgagatt ttgacgacac cggtgggaga ttttattgcc tatggtaaca atgctagtaa
    11521 gtgttttggt gtggttgggt caggaaatcg taactttaat aaccaatact gcctaacagc
    11581 caagcaatac agtcaacgct ttggcttccc tgtattggct gactttgaaa tgcgaggcat
    11641 gctggaagat atcaaacatg tcgcagctat tatcgcagat ttgtatgagt tggaaaagga
    11701 gaattaatac tcaatgaaaa tcaaagagca aactaggaag ctagtcgcag gttgctcaaa
    11761 gcacagcttt gaggttgcag atagagctga cgtggtttga agagattctc gaatagtata
    11821 aagttcttat aagaggtggt tgaagttgtt caactgtttt ttgagtataa acagtcttta
    11881 agaacgtaaa aaagcataag ttcaggtctt caaaaccttg ttcttatgct ttttatcata
    11941 gaaatatttg ctgaattttc tcttgaaatg aaaccttatc ttcatctcgc gcttgtccct
    12001 taccctgctt ttccgattgc gagtgcgtag ataaagaaga tggcgaagcc aaagaggaaa
    12061 atcaatcccg caatggcaag gtgtttgagc caagaaggaa gatttttgtt ttcacgcgtt
    12121 accaaggcgt aattcaaaag agcaaagaaa ggtgttgtca ggaaagagcc aatcatggca
    12181 aagcggagca tggttgaaac ctgaccagcg aagaacttga taatgacgat accgatgata
    12241 gcagtgatgg tcatccagat gttcaaagat ttacgattgt cctctttttg actgattagc
    12301 agtcggagag attcctgatt aacgcgagaa tagccatcga taacagttat aactgttcca
    12361 aagatacaga ggaaggcaat aaaggtaatc aagtaacggg accattcgcc aagaacagag
    12421 gcatacatgc ccacgaattg agagatgtat ttggctgaag cagcttcaac cgcctgccct
    12481 gtaggatact gaatcagtgc tcccagtgcc acaaagaaga cggctaggat agctgttcca
    12541 atataaccag tgttaaagtc aaacagagcg tcttctgtgt taaagttgac ggtctttctc
    12601 ttttcagctg accaaagtga attgatggct gaaatttcaa taggagccgg catccatcct
    12661 aggagggaga cgatgaaggg cagagctgcc atttgccaag gtgtcttctc gacaaaatca
    12721 gaactgtatt ctggatgctt gaccgccgca atgataactg caagaacagt cgcaatggtt
    12781 aaggcagaca taatccattt gaccatgccg tctaaaagtt tgtagcctcc aaagagtagc
    12841 atagcccaaa tgattgcaac gagaatgagg gaccactgag taatgctaag tccaatcatt
    12901 gggaaagcac tggcgatgat agctgagcac agaatggcaa caccagccgt gttgaccata
    12961 gccgaaaaga cattgaggat aaagaaaatc cagagataga gttttccttt ttcggcataa
    13021 ccttcaacca aagtctttcc agtatcagct gtgtattcag caccaaaacg gaaaaatgga
    13081 tatttaaaga cattggctaa gatgaccaag agaagtagag accaaccgta agaaccgcca
    13141 gcttgagttg aggatacaat gtgggaacct ccaacagcgg cagttgccat taggattcca
    13201 ggtcccattg cttttagctt gcttgcccag gttgattgat ttaaggtaat agcttgcgac
    13261 atgataaata ctcctttttg aattttcaga ataatctgta tatgtaatct atattctaca
    13321 aaaaattttg gaaaaatgca agaatatttt gaaaaaagat agaaaattta caaagaaaat
    13381 ctgaaataat tgttatgata tag
//
LOCUS       DAVLHB010000053        13017 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLHB010000053 DAVLHB010000000
VERSION     DAVLHB010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.053"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(52..444)
                     /gene="rpsI"
                     /locus_tag="VXE36_001759"
     CDS             complement(52..444)
                     /gene="rpsI"
                     /locus_tag="VXE36_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0780012.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(463..909)
                     /gene="rplM"
                     /locus_tag="VXE36_001760"
     CDS             complement(463..909)
                     /gene="rplM"
                     /locus_tag="VXE36_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0780013.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1265..1582
                     /locus_tag="VXE36_001761"
     CDS             1265..1582
                     /locus_tag="VXE36_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0780014.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(1627..2439)
                     /gene="folK"
                     /locus_tag="VXE36_001762"
     CDS             complement(1627..2439)
                     /gene="folK"
                     /locus_tag="VXE36_001762"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0780015.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLET
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2482..3036)
                     /gene="folE"
                     /locus_tag="VXE36_001763"
     CDS             complement(2482..3036)
                     /gene="folE"
                     /locus_tag="VXE36_001763"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0780016.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3017..4339)
                     /locus_tag="VXE36_001764"
     CDS             complement(3017..4339)
                     /locus_tag="VXE36_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0780017.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4341..5321)
                     /gene="folP"
                     /locus_tag="VXE36_001765"
     CDS             complement(4341..5321)
                     /gene="folP"
                     /locus_tag="VXE36_001765"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0780018.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGRGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSS
                     LIFPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEEIGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5416..6123)
                     /locus_tag="VXE36_001766"
     CDS             complement(5416..6123)
                     /locus_tag="VXE36_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0780019.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLMVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6176..7594)
                     /locus_tag="VXE36_001767"
     CDS             complement(6176..7594)
                     /locus_tag="VXE36_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0780020.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            7784..8596
                     /locus_tag="VXE36_001768"
     CDS             7784..8596
                     /locus_tag="VXE36_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0780021.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            8935..9954
                     /gene="adhP"
                     /locus_tag="VXE36_001769"
     CDS             8935..9954
                     /gene="adhP"
                     /locus_tag="VXE36_001769"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0780022.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10187..11176
                     /gene="manX"
                     /locus_tag="VXE36_001770"
     CDS             10187..11176
                     /gene="manX"
                     /locus_tag="VXE36_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0780023.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVANAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11204..12007
                     /locus_tag="VXE36_001771"
     CDS             11204..12007
                     /locus_tag="VXE36_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0780024.1"
                     /translation="MSIISMVLVVGVAFLAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPATLL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12031..12942
                     /locus_tag="VXE36_001772"
     CDS             12031..12942
                     /locus_tag="VXE36_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0780025.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
BASE COUNT         3777 a         2911 c         2585 g         3744 t
ORIGIN      
        1 aaaaagaaca ccccgaaagg tgctctgtat aagtatagta attctttcga attaacgttt
       61 actaaattgt gatgctttac gagctttctt aagacctggt ttcttacgtt caactttacg
      121 tgagtcacgt gtaagaagtc ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg
      181 aagaagggca cgagcgatac cgtgacggat agctcctgat tgaccagcgt atccaccacc
      241 tataacgtta acgaaaacgt cgtatgaacc tacagttgaa gtaactgcga atggttggtt
      301 gatgacaaga cgaaggtcag cgtgtgggat gtactcttca acatcttttt tgttaacagt
      361 gattttacca gttcctggaa caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt
      421 acctgcatat tgtgcttgtg acatacttta ttgttccttt ccttagataa gtcctgaaat
      481 gtcaagaact tctggttgtt gtgcagcgtg agtgtgctca gctccaacaa atactttcaa
      541 cttcatacct tgagcgcgtc caagtgtatt gtgtggaagc atacctttaa ctgatttctc
      601 aatcaaacgt actgcatttt tagaacgaag ttcacctgca gagatttgtt tcaatccacc
      661 tgggtggttt gagtgagtgt agtagatttt atcagttgct tttttaccag tcaatttaac
      721 tttttcagca ttgataacaa tcacgaagtc acctgtatca gtgtgtggtg taaatgttgg
      781 tttgtttttt ccgcgaagta cgctagcaac tactgcagaa agacgtccaa gtggtacatc
      841 agttgcgtca actacgtacc atttacgttc aacttggcct ggtttagcca taaatgttgt
      901 tttgttcatg atttctccta tatatagttc gatttttgtt tacggtgatg ggtgttcctt
      961 cccatcgaaa agtatttgga aggttccggg gcctttcaaa tggggtaaac aataccgcct
     1021 actatcatac caaattttac ccctaaaagt caatagatat gaaaaatatt tttcggtaac
     1081 ttctcaaagt aactgaaagt tatataatca agttaatttg ggaatttacc tattaacttc
     1141 ggtagatttt taggaatttt ttccctattt ctccctgtaa ctaaaatcct tttcaaaaaa
     1201 tcaccttttc ttgattttta atcctatttg ctgtatgata agggaaaaga aaggggacag
     1261 agatatggct tttaccaata cccacatgcg atctgctagt tttggcattg ttaccagctt
     1321 gcctgatgac atcattgact ctttttggta tatcatcgac catttcttaa aaaatgtctt
     1381 tgaattggaa gaagaactcg agtttcaatt gcttaataac caaggaaaga ttaccttcca
     1441 cttttcaagt caacacctcc ctacagccat tgattttgac tttaaccatc ctttcgaccc
     1501 tcgttatccc ccaagagtac tggttttaga catggacggt agagaaacta tcctcctccc
     1561 agaagaaaat gacctatttt aaaaactcta gccttcagtt gcaagtaact gaaaactaga
     1621 gtttttctat tttttcaaag catcatacaa gttgcggatc ggttgtttta atatcggatg
     1681 gataaaatga ggcgcaattt cctgtaagga ctcaaggaca aaaaggcgtt ccgctatgta
     1741 aggatgaggc aatatgaggt cgtctgtata aaggatctgg tcctccacaa agagcaagtc
     1801 caaatcaatc aaacgaggtc cccaatgcac ttctctcacc cgtcccagct ctgactcaat
     1861 ggctaacaag gtttctaaca agtcttgtgc tggtagccag gtttccacct caaccacttg
     1921 attggcaaag ctatcctgct ccactccacc ccaaggctcc gtctctaaga cactggactc
     1981 tttgagaata tggatgccac gagctcgcag tttgtcaatg gcttgcttca agtttacttg
     2041 tttatctccc atattgcttc ctagggcgat aaaggctcgt tgcttgcggc gatgaatggt
     2101 taccgagcaa gtatctagtg acaaatgcac cggtgcccaa ggttttttca gttccaactt
     2161 catttcttgg acaagaggat aagactcaaa ggtacgttcc accagtttat aggctaccgt
     2221 ttcaatcaaa tcttcactcg tttcctgaaa ccaagtcgtc cactgctgac acaattctcc
     2281 gtaatggaca gaggctgtta aatccaagtc tgtagctgcc ttggtcatat cataggatag
     2341 gatggctgaa acgacaaatt tctgccccaa ttctttctca ctaggaaaaa gaccatgata
     2401 ggcaaacatt tccaaatcct taatctgcag ttgatccata atgattcctt tctagaaaaa
     2461 tccgcttgaa gcggattctt tttatagccc cattaaacga taagcttggt cgcggaggtc
     2521 cttatctgtt tcaaatagac cacgagctac tgtcgtcaag gttgcagtgc ctggttttct
     2581 aacaccacgc atactcatac acatatgttc cgcctcaatg acaacaaagg ctcctttagc
     2641 acctagatag tccatcaagg catcggccac ttcgatattc aaacgttctt gaatttgtgg
     2701 ttttttcgaa taaacttcaa ccgtacgggc tagcttagac aagcctgcca cacgaccatc
     2761 tggaatgtag gcaatgtgcg ctctaccata aaatggcaag aagtggtgtt cacacatggt
     2821 atggaaaaag atatcctttt ctaccaccat attatcgtca ataatttcaa aggattttga
     2881 caaatgttcc tctgctgttt gaccaagacc tgaaaaaatt tcttgataca tacgggctac
     2941 acgagcaggt gtttcctgca agccctcgcg attagcgtcc tctcctacag cctcgataat
     3001 catttttaca gctgcttcaa tcttttgtgt atccattctc gttcttcctc tccatcagat
     3061 aggccctcac ttggctcaag aaatacaagg aacctgtgac aatcctaact gtttgtttct
     3121 cttctttttt atctgtcaaa ttctgctcta gaaaatcatg ccaatcttgg tagctgagat
     3181 ttctagactt agctgcctct ttcagcacgc tttcatccgt cgcccgacta tccgcaaaat
     3241 gtgttagagt aagctcggta tctggcatgg ctcccagcaa gtccaacata tcctccaagg
     3301 ccttggtttt gatacaagtg aagaggattt ccttatgata atccgcaaaa cgttcttgca
     3361 aggttaccaa caaggccttg atagcatggg gattgtgggc tccatccaaa atcatcaagg
     3421 gatctcttga cacgatttcc aaacgccctg gccaacttgt ttcttccaag gcttgaccaa
     3481 gaaaatcatt gcttgctagc tctcgaccat cttcttgaca aaaagtatca agtaaagcta
     3541 tggccatccc agcattctct atttggtaca aaccaagcag gctagtctgg aagcgacctt
     3601 gtctgacagc acttgtatag tcaaagactt cccctgtcac cacactttct tgatgacgaa
     3661 cctgataatc tgtcccgtag gcaagtctcg gcgcatcttt cccttccgca atgcggtcaa
     3721 tcacagccaa ggcttctgga gcaatacgcc ctgttaccaa gggtatccct tgtttgataa
     3781 tacctgcctt ctgctctgct atggcctcca aggtgtcacc aagtagagcc acatgatcca
     3841 agccaatagt tgtaattcct gtcaaaatgg gctgacagac attggtacta tccaaaagtc
     3901 cacccatgcc aacttccatg atggccacat ctacttgctc tgaggcaaag tagtcatagg
     3961 ccagggctgt gataatctca aactcggttg tgccctgtaa attggcgacc gcttctccct
     4021 ccagcaaaga ctgatagtct gccatgagag cttctagcct cgcttctgag atcgattccc
     4081 cattgatgct aatctggtct gtgtaatgaa tgagataggg cgagctaaac acgccaactc
     4141 tcagccctag cttttctagc atctttttca aaaaagcaat agtcgagccc ttgccgttag
     4201 tccctccgat atggaggacc ttgagtttga gatggggatt gccacgcaaa gctaacagtt
     4261 ccaccattcg ttccaatcca aaatgcggtt gatccgtccg gtagttagca atccactgat
     4321 tgttttcaat ttctttcatc ttatttatat tgttttaaat ctaaattttc cgcttcatca
     4381 gccagacgaa tggcagaggc aatttcaact gccatcctgt gactagctac gtcatgcacg
     4441 cgcaccactt ctacaccctg tctcgcagcg atactggtta catgagccga agccgtgtcc
     4501 cgattgcgga aaccaagctc tgtctcagga ttgacttcaa acccaatttc ttcaaggata
     4561 ttgatgacaa atcgcttgcg cgacactccg agaaagattg gatagccctt ctgatgtagt
     4621 ttatccaggt cccgtaaaag aagcagattt tctttcttgg tcagaccaaa gccaattcct
     4681 ggatccaaca ggatattttc tggtgcaata ccagcttctg ccgctctcgc tagtgctcgt
     4741 tcaaagaaag cctccatcaa ttcttcgatt ggcaatgttt caaagtcagc taactcttcc
     4801 tctgtaaaag cttgaccaaa accaaaatga gggaagatga gcgagctagg gtgctgaggt
     4861 cgcgccataa ctggattaaa catgatgacc acttgcgctc tcgcttcagc taccacatga
     4921 gccattttct catcacccat aagaccagtg atatcattga ctagatcggc accagcagcc
     4981 aaagcagcct ctgctacttg actcttccaa gtatcaatag agatgaggac atcactttcc
     5041 ttgcgaatcg ctttgatcac tggaacaaca cgctggattt cctcttctat ctcaacatag
     5101 ctacttcccc ttcccggccg agtcgattct ccgccgatat cgagcatact ggctccttct
     5161 gctatcaatt tacgagcctg ctggagtgcc tgctcaagag caaaaaattg accaccgtcc
     5221 gaaaaggagt ctggggttac attgataatt ccgcaaataa ctgtctttgc atgattggct
     5281 ttacttgaca tatcggtcac tccctcaagg attttcatca tattattttt ctattttacc
     5341 ataaaaagaa aaagatggac acgattgcat tcatctttcc ctagtagaaa gaggtcggtt
     5401 cctacataaa aacttttaca cagaaattcc taatgtccga ctcataatca ccacaagagc
     5461 caacaaacag aaagcaatcc cattaacaat catgtgaagc aagatcgaca tttccaaacg
     5521 ttgggtcttg taggccgtcc aagatagaac tgtcgacata cctccataaa tcaataaaga
     5581 aggtaaatta cttggttgat gcaataaagc aaacacaatc gtaccgacta caaatcccaa
     5641 gttctccttg cctcggaaaa tctttttagg aacaagccca cggcacaaga tttcctcaca
     5701 aatcggagca agcaaggcta gcaagaagaa actggaaatc aacgaactat tttgaaccat
     5761 atcattaatc tgagactggt tagctgttgt cgtctcattt gacagttgca acaagataga
     5821 accaagtata tttgacccga caataactaa ataactcaaa cccaaacgtg ccaaatcttt
     5881 agctctaaaa aaagaaaaat taaaactagc taacttggtt ttacgagctc ccataataaa
     5941 tagagccaga accacaattg aaaggccagc aaccatcagc cctgactgta gcagggctac
     6001 ttcttttaaa gtcaaaatag aggtaaccac taggggaacc tgatataaaa ggacggcaag
     6061 taaaaagacc aaaatccagc ctgcacgatt caacaattct ttccacatat ttttctcttt
     6121 catcacctat ctcctttgta ttaaaaaagg ggggaaatcc ccctgggtca ttctattata
     6181 aggccatgct aatgtagtta aggataaaca aggcatccaa aatccaaatc atggcatgaa
     6241 catctttaac ttgaccttta acaagcttag tcaaagtgta agtcaagaaa ccaactgcaa
     6301 tcccttgagt gatagagtag ctgaatccca taaagataga tgtgaagaag gcaggaactg
     6361 cttcagacat atcatcccaa tggatatttt tcaagctacc aagcatcata atcccaacga
     6421 taatcaagat tggagctgta gccgctgttg gtacgatcgc tagaagcggg ctaaagaagc
     6481 ttgaaatcgc aaaacagata gctacaacca aggctgtcaa accagtacgt ccacctgcac
     6541 cgataccagc agcagactca acataagtcg ttacgtttga agtacctgca atggcaccga
     6601 ctgtcgttcc aatcaaatca gagtaaagag ccttatccaa tttggctgat tggtgatttt
     6661 caccatttgt cgctacaata ccaacttttt cacctgtacc gatcaaggta ccaattgtgt
     6721 caaaaatatc tgtcaatgag aaggcaagaa tggccatcag agtttcaggc aagcgagctg
     6781 tatctgaaac caaagctccc aaaccttctg aaccaagagc tgcaccaaag attgtcttca
     6841 aatcttcaaa agctgcacca acatggttat tagcaaaatc gatactagac aaatcaacca
     6901 aaccaactgc aatagcaaga acagttgttg tcaagataga gagaataatt ccccctttaa
     6961 tccctttgat gacaaagaag atagtaatgg caagtcctgc aagagccact aaaacagctg
     7021 gattattaaa gctgaccaat cctggaactg ctgaagagtt tgctgcaatc gttgcttgag
     7081 ctttgtcagc cccttctcct acaacagtat agttgcctgg atcaatcgtg aatttcaaaa
     7141 gtccagcatt cttaatccct acataggcaa ggaagacacc gataccagct gaaatagctg
     7201 agcgaagagc attgggaatc gattcaatga tcattttacg aacatttgtc aaggtaataa
     7261 tcaatgaaat aatcccacag atgaagacca tagctagggc ttcttgccaa gaataaccaa
     7321 gcccgaatac aactgtaaag gtaaagaagg cattgagtcc catacctggc gcttgggcat
     7381 aaggtaagtt agcataaaaa gccatcatca aggtacccgc tactgcacca ataatcgtcg
     7441 ctaggaagac gccctgagca ggcattcctg tttgtgaaag tatttgtggg tttacaaaga
     7501 gaatatagct cattgcaaag aaagttgtta aaccagcgag aacctctgta cgaacgtctg
     7561 taccgttctc ttttagttta aataatttgt ccatcatcaa tctcctttta atttttacga
     7621 acaataatag aattatatca tttatcattc actttttcaa tgtctttgtt tgatttgttt
     7681 aagaaattaa tccaatttca ttttttgttt ggaatctgct tttctgcctg ctttctgtta
     7741 taatagaaga catcttatct gaaaacacac tagaaaggtc catatgacga aaaaaattat
     7801 tgcagttgac ctagatggaa ccctgctcaa ctcagacagt caaatttctg actttaccaa
     7861 aaaaaccatc aaaaaagttg ctgaaaaagg ccatcaggtt attattacga caggtcgccc
     7921 ttaccgtatg tcaaaagatt tttaccgtga actgggctta gacactccta tgattaactt
     7981 caacggatcc cttactcatt taccagacca agtttgggat tttgaaaagt gtttgactgt
     8041 agacaaaaaa tatctgctag atatggttca acgttcagag gacattcaag ccgattttat
     8101 cgctggagaa tatcgtaaaa aattctacat tacaaatccc aatgaagaaa ttgccaatcc
     8161 caaactattt ggtgtagaag ctttccagcc tgaagatcaa ttccagcctg aattggtgac
     8221 caaggaccct aactgtatcc tcttgcagac cagagccagt gacaaatatg ccttggcaaa
     8281 agacatgaac gccttctacc agcatcaact ttctatcaat acctggggag gtccgctcaa
     8341 tatccttgaa tgtaccccaa aaggtgtcaa caaggccttt gctttggact acttgctcaa
     8401 gataatgaat cgtgacaaaa aagatttgat tgcctttggg gatgaacaca atgataccga
     8461 aatgctcgct tttgctggga agggttatgc catgaaaaat gccaatccag agctactccc
     8521 ttatgcagat gagcaaattt cccttaccaa cgaccaagat ggggttgcca aaaccctaca
     8581 agacttattc ttataaccta tactgatact caatgagaat caaagagcaa actaggaagc
     8641 tagccgtagg ttgctcaaag cactgctttg aggttgtaga tgaagctgac gtggtttgaa
     8701 gagattttcg aagagtatga ccagcttgca agctggtctt tgtgctcttt tcacagtctc
     8761 atcaaccagt taatcgattg ttctactttt tgtctccaaa accttggaaa aggctttctt
     8821 ttgtgatata cttcacatat aaatacaaga gagctcgtca cactcgactc tgttgacaaa
     8881 aaatcaatcc agtcccgttg tccctgttct cggtcaatat caaggaggat agctatgaaa
     8941 gctgttgttg taaatccaga aagcactggt gttgctattg aagaaaaagt actccgtcca
     9001 cttgaaactg gggaagcact tgtagaagtt gaatactgtg gcgtttgcca caccgacctc
     9061 cacgttgctc atggtgactt tggtcaagtc ccaggacgtg ttcttgggca cgaaggtatc
     9121 ggtatcgtta aagagattgc tccagatgtg aaaagcctta aagtcggtga ccgcgtcagc
     9181 gttgcttggt tctttgaagg atgtggcact tgcgaatact gtacaactgg tcgcgaaacc
     9241 ctttgccgta cagtgaaaaa tgctggctac tcagtagacg gtggtatggc tgaacaatgt
     9301 atcgtaactg ctgactatgc tgtcaaagtt cctgacggac ttgatccagc ccaagcttct
     9361 tctatcacat gtgctggagt aacaacctat aaagctatca aagaagcaaa agttgaacca
     9421 ggccaatggg ttgttcttta cggtgctggt ggacttggta acctcgctgt tcaatacgct
     9481 aaaaaagtat tcaatgctca tgttatcgca gtcgatatca acaatgacaa acttgccctt
     9541 gcaaaagaag taggcgctga cattgtgatt aacggcctcg aagttgaaga tgtagctgga
     9601 ctcattaaag aaaaaactga tggaggagct cattcagctg tcgtaactgc tgtgtctaaa
     9661 gttgccttca accaggctgt tgactccatt cgtgctggtg gtcgcgtcgt cgctgttggt
     9721 cttccttctg aaatgatgga actcagcatc gttaaaacag tcctcgatgg aatccaagtc
     9781 atcggttctc ttgtcggaac tcgtaaagac ttagaagaag ccttccaatt tggtgcagaa
     9841 ggtctggtag tcccagttgt tcaaaaacgt ccagtagaag atgctgttgc cattttcgac
     9901 gaaatggaaa aaggccaaat ccaaggacgt atggtactcg acttcaccca ctaatctaat
     9961 agaaacctat tttaaaagtt ggaagaagct tccaactttt ttatattaaa ttttaaataa
    10021 gaattcaaga ttactcctca aaaactcaac atatcaacat acaaaaataa aaatttttta
    10081 attttttatg ataaatagtt gcttttttta tgaaaacggt ttatacttaa acagtcttaa
    10141 agttttctta aatgaaaact aaaacaaaaa aggaggaatg acaataatga gtatcggaat
    10201 cattattgcg agccacggcg aatttgctgc gggtattcat cagtcaggat ctatgatctt
    10261 tggtgaacaa gaaaaggttc aagttgtgac ctttatgcca aatgaaggtc ctgatgatct
    10321 atacgctaag tttaataacg ctgttgctgc atttgacgca gaagatgagg ttctagtttt
    10381 ggctgacctt tggagtggtt ctccatttaa ccaagctagt cgcgtgatgg gagaaaatcc
    10441 tgagcgtaag tttgccatca tcacaggact taacttaccg atgttgattc aagcctacac
    10501 agagcgcctc atggacgctg ctgcaggtgt agaaaaagtc gctgctaata tcattaaaga
    10561 agccaaagat ggcatcaaag ctcttccaga agagctaaat ccagttgaag aagttgcaaa
    10621 cgctgcagct gctccagttg cccaaactgc tatcccagaa ggaactgtta tcggagacgg
    10681 taaattgaaa atcaatcttg cccgtcttga cacacgtcta cttcacggtc aggttgcaac
    10741 tgcttggact ccagattcaa aagcaaatcg tatcatcgtt gcttcagata acgtggctaa
    10801 agacgacctt cgtaaagaat tgattaaaca agcagctcca ggtaatgtca aggctaacgt
    10861 ggttccaatt caaaaactga ttgagatttc aaaagaccca cgttttggag aaacacatgc
    10921 ccttatcttg tttgaaacac ctcaagatgc ccttcgtgcc atcgaaggcg gcgtgccaat
    10981 caagactctt aacgttggtt ctatggctca ctcaacaggt aaaacattgg tcaataccgt
    11041 tttgtctatg gacaaagaag acgttgctac atttgaaaaa atgcgtgact tgggtgttga
    11101 atttgatgtc cgtaaagtac caaatgattc taaaaaagat ttgtttgact tgattaacaa
    11161 agccaatgtc aaataagcca ttatttatga aaggatttta aatatgtcta ttatttctat
    11221 ggttttagta gtcggtgtag ccttccttgc aggtcttgaa ggcatcctcg accagttcca
    11281 atttcaccaa ccacttgtag cctgtaccct tattgggctt gtaacaggtc acttggaagc
    11341 agggattatc ctcggtggat cgcttcaaat gattgccctt ggttggtcaa atatcggtgc
    11401 tgctatcgct cctgatgctg cacttgcttc tgtcgctgct gccattatca tggttcttgg
    11461 tggtgacttt accaagacag gtatcggtgt tgcccaagcg gttgctatcc ctcttgccgt
    11521 tgctggtcta ttcttaacta tgattgtacg tacaatttca gttggattgg ttcacactgc
    11581 tgatgctgcc gctaaaaaag gtgacttcgg cgctgtggag cgtgcgcatt ttattgcgct
    11641 acttttccaa ggacttcgta tcgcgcttcc tgcaactctt ctccttatgg taccaactga
    11701 aactgtacaa agtatcctta gtgccatgcc agactggctc aaagatggta tggctatcgg
    11761 tggtggtatg gtcgttgccg ttggttacgc catggttatc aacatgatgg caactcgtga
    11821 agtatggcca ttcttcgctc ttggtttcgt tctcgctgct gtgtcagata ttactctaat
    11881 cggattcggt gctatcggtg ttgctatcgc tcttatctac cttcatcttt ctaaaactgg
    11941 tggaaatggt ggcggaggag ccgcaacttc taacgaccca atcggcgata tcctagaaga
    12001 ctactaagat aagaaaggac tgaaaacatc atgactgaaa aacttcaact aactaaatca
    12061 gatcgtaaaa aagtttggtg gcgttcaacc ttcttacaag ggtcttggaa ctttgaacgg
    12121 atgcaaaact tgggctgggc ttatacactc attccagcta tcaaaaaact ctatactaaa
    12181 aaagaagatc aaatcgctgc tcttgagcgt caccttgagt tcttcaacac tcatccatac
    12241 gtagctgctc cagtcatggg ggttactctt gcgcttgaag aagaacgtgc taacggtgtg
    12301 gaaatcgatg acgctgctat ccaaggggtt aaaatcggta tgatgggacc tcttgctggt
    12361 atcggtgacc cagtattctg gtttacagta cgcccaatcc ttggatctct cggtgcttca
    12421 cttgccctta ctggcaatat cttggggcca ctcctcttct ttgttgcatg gaacttgatt
    12481 cgtatgtcat tcttgtggta tgttcaagag attggataca aggctggatc agaaatcact
    12541 aaagatatgt ctggtggtat ccttcaagat atcactaaag gagcttctat ccttgggatg
    12601 ttcattcttg ctgtccttgt tcaacgctgg gtaaatatta aatttgcttt cgatgtttct
    12661 aaagttcaac tagatgaaaa ggcttatatc cattgggata aattgccaga agggtctaaa
    12721 ggtatccaag aagcattcgc acaagtagga caaggattgt ctcaaactcc tgaaaaagtt
    12781 actactttcc aacaaaactt ggatatgttg attcctggat tatcaggact actccttact
    12841 ttactttgca tgtacttact taagaaaaaa gtatctccaa tcactattat ccttgctctc
    12901 ttcgcagtgg gtattgtggc acatgttctt cacatcatgt aatcaagcaa ctaaaaagga
    12961 accaggttct aaaatctgat tccttttttg gctctttgtc aactgtagtg ggttgaa
//
LOCUS       DAVLHB010000054        12746 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLHB010000054 DAVLHB010000000
VERSION     DAVLHB010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.054"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            473..1594
                     /gene="mnmA"
                     /locus_tag="VXE36_001773"
     CDS             473..1594
                     /gene="mnmA"
                     /locus_tag="VXE36_001773"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0780026.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1735..2190
                     /locus_tag="VXE36_001774"
     CDS             1735..2190
                     /locus_tag="VXE36_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0780027.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2200..4113
                     /gene="mnmG"
                     /locus_tag="VXE36_001775"
     CDS             2200..4113
                     /gene="mnmG"
                     /locus_tag="VXE36_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0780028.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELTETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4302..4391
                     /locus_tag="VXE36_001776"
                     /pseudo
     CDS             4302..4391
                     /locus_tag="VXE36_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4493..6172)
                     /locus_tag="VXE36_001777"
     CDS             complement(4493..6172)
                     /locus_tag="VXE36_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0780029.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6174..6407)
                     /locus_tag="VXE36_001778"
     CDS             complement(6174..6407)
                     /locus_tag="VXE36_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0780030.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6789..7010
                     /locus_tag="VXE36_001779"
     CDS             6789..7010
                     /locus_tag="VXE36_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780031.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7223..7375)
                     /gene="cibB"
                     /locus_tag="VXE36_001780"
     CDS             complement(7223..7375)
                     /gene="cibB"
                     /locus_tag="VXE36_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0780032.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7377..7562)
                     /gene="cibA"
                     /locus_tag="VXE36_001781"
     CDS             complement(7377..7562)
                     /gene="cibA"
                     /locus_tag="VXE36_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0780033.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7740..8423
                     /gene="tsaB"
                     /locus_tag="VXE36_001782"
     CDS             7740..8423
                     /gene="tsaB"
                     /locus_tag="VXE36_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0780034.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8420..8857
                     /gene="rimI"
                     /locus_tag="VXE36_001783"
     CDS             8420..8857
                     /gene="rimI"
                     /locus_tag="VXE36_001783"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0780035.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8847..9857
                     /gene="tsaD"
                     /locus_tag="VXE36_001784"
     CDS             8847..9857
                     /gene="tsaD"
                     /locus_tag="VXE36_001784"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0780036.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9897..11203)
                     /locus_tag="VXE36_001785"
                     /pseudo
     CDS             complement(9897..11203)
                     /locus_tag="VXE36_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11478..11829)
                     /locus_tag="VXE36_001786"
                     /pseudo
     CDS             complement(11478..11829)
                     /locus_tag="VXE36_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11936..12232)
                     /locus_tag="VXE36_001787"
                     /pseudo
     CDS             complement(11936..12232)
                     /locus_tag="VXE36_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12475..>12746
                     /locus_tag="VXE36_001788"
     CDS             12475..>12746
                     /locus_tag="VXE36_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV0780037.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNN"
BASE COUNT         3631 a         2511 c         2972 g         3632 t
ORIGIN      
        1 ggctcaggtt cccttgcagt caacacaact gtagacgggt atactgtcaa tgaaaacggt
       61 gaatgggttt aaaccgatta aattaaatca tgttaagaac atttgacatt ttaattttga
      121 aacaaagata aggttcgatt gaatagattt atgttcgtat tctttaggta cctgtcttat
      181 gatttcagga aatgtcatta aaaaaacgac tccttttctc taacttgaaa aatagattag
      241 agaaaatggg ttgttttatt tattatagtt atttgaatga agataagaag aaggtatact
      301 cacgtcattc acataatctg tatattgact ataagtttta aaaaacaatt tttaagctct
      361 tccttgtctt ctctaaccaa gcgtgttata atgaatactg ctcaagcgac cttcaatcgt
      421 gaagcacaca cgaccttcaa tcgtgaataa acgaatagat gggagactta ccatgagtga
      481 taactctaaa acacgtgttg tcgtggggat gagtggtggt gttgattcgt cggtgacggc
      541 tcttttgctc aaggagcagg gctacgatgt gatcggtatc ttcatgaaga actgggatga
      601 cacagatgaa aacggcgtct gtacggcgac cgaagattac aaggatgtgg ttgcggtggc
      661 agaccagatt ggcattccct actactctgt caattttgaa aaagagtact gggaccgggt
      721 ttttgagtat ttcctagcgg aataccgtgc agggcgcacg ccaaatccgg acgttatgtg
      781 caacaaggaa atcaagttca aggccttttt ggactatgct atgaccttgg gggcagacta
      841 tgtagcgact gggcattatg ctcgagtggc gcgtgatgag gacggcactg ttcacatgct
      901 tcgtggcgtg gacaatggca aggaccagac ctatttcctc agccaacttt cgcaagaaca
      961 acttcaaaaa accatgttcc cactaggaca tttggaaaag cctgaagttc gaaaactagc
     1021 agaagaagca ggcctttcga ctgctaagaa gaaagactcg acagggattt gctttatcgg
     1081 agaaaagaac tttaaaaact ttctcagcaa ctacctgcca gctcagcctg gtcgtatgat
     1141 gactgtggat ggtcgcgata tgggcgagca tgcaggtctt atgtactata caatcggtca
     1201 gcgtggcgga ctcggtatcg gtgggcaaca cggcggtgac aatgcccctt ggttcgttgt
     1261 cggaaaagat ctaagcaaga atattctcta tgtaggacaa ggattctacc atgactcgct
     1321 catgtcaact agcctagaag ccagtcaagt ccactttact cgtgaaatgc cagaagagtt
     1381 tacgctagaa tgtacggcta aattccgtta ccgtcagcct gactctaagg tgaccgtcca
     1441 tgtcaaagga gacaaggcag aagttatctt tgcggaacca caacgcgcga ttacaccagg
     1501 acaggcagtt gtcttttacg atggcgaaga gtgtctaggt ggcggtttga ttgacaatgc
     1561 ttaccgcgat ggacaagttt gtcagtacat ttagattgac aaattttctc aatttgctac
     1621 aataataaca gcaatagaaa tgatggtcaa agctcatgga tgttgcaggc ttttttgtcc
     1681 tgcacttctt tgtagttttg actgtttttg tgtcgtttaa gggaaaggac aagaatgact
     1741 caacaagact ttcggacaaa agtagacaat acggtttttg gtgttcgggc tacagccttg
     1801 attgtccaaa atcacaagct tctagttacc aaagacaagg gcaagtatta cactattgga
     1861 ggtgcgattc aagtcaatga aagcacggaa gacgcggtag tccgtgaagt gaaggaagaa
     1921 ctgggtgtca aagctcaagc tgggcagcta gcttttgtgg ttgaaaatcg ttttgaagtg
     1981 gacggcgttt cctatcacaa tatcgagttt cattatctgg tggatttgct tgaagatgcc
     2041 ccgttgacca tgcaggaaga tgagaaaagg cagccctgtg agtggattga cttggataag
     2101 cttgaggata tccagctagt tccagccttt ttaaaaacag ccctaccaga ttgggaaggc
     2161 caactaagac acattcatct tgaggaatag gagagaaaca tgacttatca ttttactgaa
     2221 gaatacgata ttattgtaat tggtgcggga cacgctgggg ttgaggcttc cttggccgct
     2281 agccgtatgg gctgtaaggt cctgcttgcg accatcaata ttgaaatgct ggctttcatg
     2341 ccttgtaatc cctctatcgg tggttctgct aaggggattg tcgtacgtga agtcgatgcc
     2401 ctcggtggcg agatggccaa gaccattgac aagacttaca tccagatgaa gatgctcaac
     2461 acagggaagg gaccagccgt tcgtgccctt cgtgcgcagg ctgataagga actttactct
     2521 aaggaaatgc gcaagacagt tgaaaatcaa gaaaatctga cccttcgtca aaccatgatt
     2581 gatgagattt tggtggaaga tggcaaggtt gtcggtgtgc gtacagccac ccatcaagaa
     2641 tatgctgcta aggctgttat tgtgacgaca gggactgctc tccgtgggga aattatcatc
     2701 ggagacctca agtactcatc aggtcctaac cacagcttgg cttctattaa cctagctgac
     2761 aatctcaagg aactgggtct cgaaatcggt cgtttcaaga caggaacccc tccacgtgtc
     2821 aaggcctctt ctatcaatta cgatgtgaca gaaattcagc caggagacga agtgcctaat
     2881 catttctcat acacttcacg tgatgaggat tatgtcaagg accaagtacc atgctggttg
     2941 acctatacca atggtaccag tcatgagatt atccaaaaca acctccaccg tgcgcctatg
     3001 tttacaggtg tggtcaaggg agtggggcct cgttactgtc cgtcgattga agacaagatt
     3061 gtgcgctttg cggacaagga acgtcaccaa ctcttccttg agccagaagg gcgcaatact
     3121 gaggaagtct atgtgcaagg actttcaacc agtctgcctg aggatgtcca gcgtgacttg
     3181 gtgcattcca tcaaaggttt ggaaaatgca gagatgatgc ggacaggtta tgctattgag
     3241 tatgatatgg tcttgcctca tcagttgcgt gcgactttgg aaaccaagaa aatctcaggt
     3301 ctcttcactg ctggtcagac aaatggaacg tcaggttacg aagaggcagc aggccaaggg
     3361 attatcgcgg gtatcaatgc ggctctgaaa atccaaggca agcctgaatt gattctaaaa
     3421 cgaagtgacg gttatatcgg ggtgatgatc gacgacttgg tgaccaaggg aaccattgaa
     3481 ccttaccgtc tcttgaccag tcgtgctgaa tatcgtctca ttcttcgtca tgacaatgct
     3541 gatatgcgtt tgacagagat tggccgcgag attggccttg tggatgatga acgctgggct
     3601 cgttttgaaa tcaagaaaaa tcaatttgat aatgagatga aacgcctaga cagtatcaaa
     3661 ctcaagccag tcaaggaaac caatgctaag gttgaggaaa tgggcttcaa gccgttgaca
     3721 gatgcggtga cagccaagga attccttcgc cgtccagaag tttcttacca agatgtggtg
     3781 gccttcatcg gaccagctgc agaagacttg gatgacaaga ttatcgaatt gactgaaaca
     3841 gaaatcaagt acgaaggcta tatttccaaa gctatggatc aggttgccaa gatgaaacgc
     3901 atggaagaaa aacgcattcc agccaatatc gactgggatg acatcgattc tattgcgaca
     3961 gaagctcgtc agaagttcaa actcatcaat ccagaaacca tcggccaagc cagccgtatt
     4021 tcgggagtaa acccagcaga tatttctatt ttgatggtgt atctggaagg taaaaatcgt
     4081 agtatttcta aaactcttca aaaatcaaaa tgatacgtcg tcggcttctt acgaatgagt
     4141 tcaaagcttg gctttgattc atctccaacc tcccatagtt ccccgaacta tgggagctaa
     4201 ctcaagttat gcattttcct agccttctgg tctgattttc attgagtttt aatctcaaaa
     4261 gaaagcatag agaaaaacag ctccgaagac ggggctgttt tgttgacttg tactcaatga
     4321 aaatcaaaga gcaaactagg aagctagccg taggttgctc aaagcactgc tttgaggttg
     4381 tagatagaac tgacgaagtc agctcaaaac accgttttga ggttgtggat agaactgacg
     4441 aagtcagtaa ccatatatac ggcaaggcga agctgacgtg gtttgaagag tattattctt
     4501 catctggtgt gaggatcatc gggatgatga tcggttcacg ttcggtattt tcatagagga
     4561 aggggcgaat agcgttgaca atggcaccat tgacagattg cacgctagca tccttatttt
     4621 tcagtgcgat acgaatggca ttgaagagga tacgctggct ttggcgaatc aagtcgccag
     4681 actctctcat gtagacaaag cctcggctga ggatatctgg accagataga atcatctgcg
     4741 atttgaagtc aacagttgcg actgccagaa cgacaccgtc ttcagataga tcgcgacgat
     4801 ctttgaggac agctgcgcca atttcaccga tacgatttcc atcgacatag atatcttggg
     4861 cgttgaaatg acctgcgata cgagctgagt cagcagtaag ggcaagcaca tcgccattgc
     4921 tcatgataaa gatattgtcc ttctcaacac cagtatccac tgctagtcca gcgtggactt
     4981 tttgcatgcg gtattcaccg tggacaggca tgaagtattt tggcttaatc aagcagagca
     5041 tgagtttttg ctcttgctga ccaccgtgtc cagatgtatg gatattgttc actttaccgt
     5101 ggataacttc gacaccagct tcagaaatga tgttaatcag cttgttgacg ctagtagtgt
     5161 ttccagggat gggactagaa gagaagataa cggtatcacc tggttgtaat tgtacttgac
     5221 ggtgggttcc gttggcgata cgagagaggg ctgccatggg ctcgccctga ctacctgtac
     5281 agaggatcag aatctcaccc gcaggatagt ctttgatttc atttggttcg ataaaggttc
     5341 ccttaggcgc cttgatgtaa ccaagctcga ttccgttgac aatggccttt tccatagagc
     5401 gaccaaagac cgcaatctta cgtccagtct taacagcagc ttctgttgct tgctggagac
     5461 ggaagatatt tgaggcgaag gatgcaaaga tgatacgtcc ctcgatacct tggataatct
     5521 tcatgatcga ctggccgaca accttttcag agtttgtaaa ggttggaacc tcagcattgg
     5581 tcgagtcaga gaggagacag agaacaccct cttcacctag ggctgccata cggtgcaagt
     5641 ctgcaggttc accaactgga gtaaagtcga acttgaagtc acccgtacag acgattttcc
     5701 cttgaggagt atggatgaca atccccaaag gttctggaat agagtgagtc gttctaaaga
     5761 aagttgcctt gagattttta aaggtcaact cggtgttgtg gttgatttcg taaagtttag
     5821 cgttgcgcaa gaggccgtgt tcttcgagtt ttccacgaat caaagccagc gcaagcggtc
     5881 cagcgtagat cgggacattt gcttgcttga gcaggaatgg aatcccaccg atgtggtcct
     5941 cgtgtccgtg cgtaatcaaa acagccttga cgcggtcgat attgtccacg atgtaagagt
     6001 aatcaggaat gacatagtcg ataccaagca agtcatcttc tgggaattta atcccagcat
     6061 cgacgatgat aatctcatct tggtattcaa ttccgtaagt gtttttcccg atttctccca
     6121 gaccaccgat ggcaaaaacg ccaacttctt caggtttaag agtataggcc atattagaac
     6181 tccgtgattt cgaaggcgcc agtttctttt tcgtaatcta gcaatttgtc agacaagagt
     6241 tcgatatact cgatattgta ctctgggcga ttttcttcga caagttggcg agcagtgata
     6301 cggccctcaa gttctgagct ggcatcgatg tctaggtaaa gcgcgcgtgt tgtttcacgg
     6361 cgtgggctac gttcttttgt ttcttgataa aaaactttgt aaatcatata gttcctttct
     6421 atttacaggt cagcttattc caaactttta gcagatattt gcttgatttc attccatttt
     6481 gtgtctagat tgaccttgat tcgttacaat tatttcaatt ataccacaaa atgaaaaatt
     6541 agtaaaagac ggaaacgaga aagttagggg acgatttctt cggtaagcgt ttgcaaaaat
     6601 aaagaaaatg tgttatgttg ataacggaag tgaagtttat tacttgtcat aattctatat
     6661 agattttaag tcaaggaggt tgccctatgt ataacttatt tgcttttgct atcggagttc
     6721 gtttgctagc ttttatcgtt tttgttttgc gtttatggag gaaatcttct atttgccaaa
     6781 ctggaacgat gacaaaccaa gttcttgagg aaaattacct ttgtgactct ctactcgctt
     6841 tttctcctcc tcgtgaccta tgtcgtttgg tttgtatttt actttggatt aaatgcttag
     6901 atgccctgct tatgctgggg ttttttgttt ggggatgtag agatagtaga tttacgacac
     6961 gaaaattcca ccccatctat caagatgagg tggtctttgc atttttctaa aatgatatga
     7021 caatggaatt ttcaaagctt attattttta tgggagtcat tgttttgctc aaaaatagag
     7081 ttgaagcata aaaataaaac aatacaaaca gataaatcga atggtaaagg gatggtagta
     7141 atgttcaaat cattgagaat gctgagcaaa ctgtaagaga tgaagacaat aaaatttatc
     7201 cttctaaaaa tgtgtttctt atctagcatg acttaccaaa ctttttacga aggtcttttc
     7261 caatggtata acctgccata aataaagcga taccaacacc tacaccaaag ccacccttga
     7321 tttcttgcaa ttccttatta gaaatttcac gacagttgtt caaatctttc atcatattaa
     7381 tctcctccta aaaaataacc agctgccaaa ccagaaccta taagtgctgt tccacctgca
     7441 atagctttcc aagatactgc tactccaaag ataaccaagg gagcgagacc gccatcaata
     7501 tctgataatt cattttcaga taaggataaa aattgattgt caagaatgtc aaaatttgtc
     7561 attgaacttt cctccttttt tcttgttcac ttttatattc ggaaaagaaa aggaaaagtg
     7621 agcatttttt taaattattt ttagttaagt gagggcactc ttgtctgggg gcaaagaaaa
     7681 ttcccatgtg ccagcttttg tagtataata gtaagcagac aaaaagatag gaatgtgtta
     7741 tgaaagtatt agcttttgat acgtccagca aggctctttc tctcgctatt ttagaggaca
     7801 agcaggttct tgccgagacg acgattaata ttaagaaaaa tcacagtatt actcttatgc
     7861 ctgccataga ttttttgatg gcaagtttgg attggacacc caaggatttg gaccgaatcg
     7921 tggtagctga agggccgggt agctacacag gcttgcgaat tgcggtagcc actgccaaga
     7981 ctttggctca tactctgaac atcgagttgg ttggtatgtc gagtctcttg gctctggtgc
     8041 cccaccaaca agaaggtttg tttgtcccct tgatggatgc gcgtcgcaat aatgtttatg
     8101 caggatttta tgaaaatgct aaacccgtca tgccagaagc tcacttaccc tttgagcgag
     8161 tgattgagtt aatcaagggt gctagtcagg ttacctttgt cggagaagtt ggcccctttg
     8221 ttgagcagat tcaagaatac ttgccaagga ctaatttcaa agaaaccttg ccaaatgcag
     8281 ctaatctagc tctatgggcc tgggacaagg aagcagactc cttgcatgat tttgtgccga
     8341 actacctcaa gcgtgtcgag gctgaggaaa actggctcaa gaaccatacc gagtctggcg
     8401 agtcttacat taaacgccta tgatagaaat caagcgaatt caacaacagc ctgacctagc
     8461 tcaagccatc tacgctgtca tggcagctgt ttacccagtc agtccttgga cactagaaca
     8521 aatccaagca gatctgtccc aagaccagac ttggtatgca ttggcttatg atggggcaga
     8581 agtgattgga tttctagctg tgcaggagaa tctttttgaa gcagaagtcc tgcaaatcgc
     8641 tgtcaaagga gcttatcagg gtcagggaat tgcgtcagcc ttgtttgctc aattgccgac
     8701 agataaggag attttcctcg aagtcagaaa gtcaaatcaa cgagcgcaag cattttacaa
     8761 gaaagaaaag atggcagtta tcgctgagcg aaaggcctac taccatgacc cagtcgagga
     8821 cgccattatc atgaagagag aaatagatga aggatagata tattttagca tttgagacat
     8881 cctgtgatga gaccagtgtc gccgtcttga aaaacgacga tgagctcttg tccaatgtca
     8941 ttgctagtca aattgagagt cacaaacgtt ttgggggcgt agtgccagaa gtagccagtc
     9001 gtcaccatgt cgaggtcatt acagcctgta tcgaggaggc attggcagaa gcagggatta
     9061 ccgaagagga cgtgacagct gttgcggtta cctacggacc aggcttggtc ggagccttgc
     9121 tagttggttt gtcagctgcc aaggcctttg cttgggctca cggacttcca ctgattcctg
     9181 ttaatcacat ggctgggcac ctcatggcag ctcagagtgt ggagcctttg gagtttccct
     9241 tgctagccct tttagtcagt ggtgggcaca cagagttggt ctatgtttct gaggctggcg
     9301 attacaagat tgttggggag acacgagacg atgcagttgg ggaggcttat gacaaggtcg
     9361 gtcgtgtcat gggcttgacc tatcctgcag gtcgtgagat tgacgatctg gctcatcagg
     9421 ggcaggatat ttatgatttc ccccgtgcca tgattaagga agataatctg gagttctcct
     9481 tctcaggttt gaaatctgcc tttatcaatc ttcatcacaa tgccgagcaa aagggagaaa
     9541 gcctgtctac agaagatttg tgtgcttcct tccaagcagc agttatggac attctcatgg
     9601 caaaaaccaa gaaggctttg gagaaatatc ctgttaaaac cctagttgtg gcaggtggtg
     9661 tggcagccaa taaaggtctc agagaacgcc tagcagccga aatcacagat gtcaaggtta
     9721 tcatcccccc tctgcgactc tgcggagaca atgcaggtat gattgcctat gccagcgtca
     9781 gcgagtggaa caaagaaaac ttcgcaggct gggacctcaa tgccaaacca agtcttgcct
     9841 ttgataccat ggaataaaga gtggctcttt gtcaagtgta gtgggtaggc gaaaagctac
     9901 aatctggaga gtacgaaatt cgtactctct tttttgatgt tcaaagtcat caaaatccgt
     9961 tttttaaaat tgttaaagtt ccggaaacca aaggctttgc gcttgataac cttaatcaaa
    10021 ttattggtcg cttcaagttt agcgttggaa taaggcagct taagtgcgtt gataatctta
    10081 tctctatccc ttaaaaaagt ctaaaagacc gtttgaaaaa gcggatgaac cgttggcagt
    10141 tcttgctcaa tcaatccaaa gaaatggtcg gcattcttct cttgaaaatg aaagagcagg
    10201 agttgataga gttcgtagtg aacctgtaat ccctcagagt aagaaagcag cttatctcgt
    10261 acttcccgat gggttaagtg cattcgaaac gtgggctgat agaatcgttt ctgacagagc
    10321 ttgaagctat cctggtgtag taaatcagtc cagtggactg atttagcccg agcctagaaa
    10381 cgaaaaagcg agggttccaa aagcgcttga gcgcccgata ctccaaggat tttcggtcaa
    10441 attggttcat gatttggatt cgtactcggt tcatagctcg gctcagatgt tggacaatgt
    10501 ggaagcggtc aagaacaatc ttcgcctttg gaaagagttg cttagcgagc cgataataag
    10561 ggctgtacat gtccatggtg atgacctcga ccagctcccg aacctctctc tgatagcgtt
    10621 ggaaatggtt tcgaatcacc gcatgagttc gcccgtctaa aattgcgagg atggatttgg
    10681 actcaaaatc ttgggcaatg aagctcattt tgctcttttt gaagctatac tcatcccaac
    10741 tcataacttt tggcaacttg gtccaatcgg tttcaaactt aaattccctc agttttcgga
    10801 tgatggtgga agttgagacc gccaatctgt gggcaatctc agtcatagac tgcttttcaa
    10861 ggaggagctg agcgattttt tgtctcacca tgttggaaat ctggcaattt ttcttgacaa
    10921 tggatgtttg agaaacgacc accttaaggc aattcttgca ctgaaagcgg cgctttttga
    10981 gatgcagtac cgtgggtaaa ccctgacagt cgagaagcgg aattttagag gctttctgga
    11041 agtcgtattt gatcatcttc ccttgacaat gaggacaagg aggagcgggg gaatccaact
    11101 ttgcctgaac gactagatgg gtttggtatt tcagaacaga caagattttg atatttttgt
    11161 cttccaatcc gagcaaatct gtggtattct taagttgttc catatgaccc ctttctaatg
    11221 agttggttag acgcttttca ttataggtca tatggggctt tttttctaca agaaacgacc
    11281 ctataattcc tggggtggga ttacccacta cagaaattat agagcccaaa cattccaaag
    11341 tcttgtctga ctctggaatg ttttctgttc acagttgttt tgtaactgcc taataagtaa
    11401 ccgcgctata acgaggtatc taccgagatt gtcaattctc cagtatactg ttataaaaaa
    11461 caaaactgga ggatttttta tgtcccccca tcgtcccatc gactgttccg tagctgccca
    11521 ataacggagt atagtcggct gaaacaagaa taggacaaaa gtgcctcaag aaaagcatcg
    11581 taatttgaca atattattct gagatgtttt tgatgtaagc ccatattttc tcaatgggat
    11641 tatactcggg tgaataggta ggaagtggta acagtctatg ccctgctcct tacacatgtt
    11701 cattctgtga aaccttgcat tgtccataat gataagggat ggtgtatcta aagtaggtag
    11761 taagaatttt tggaagcaag cttcgaaaaa gtcactcgtc atcgtatctt tataggtcat
    11821 cggagccata gtatattgaa acaaaaaagg gcattagtac ttctataaca gtatcgcaat
    11881 ctctggtgtg cgttgtctcg atcttaattc aaataattat atcttcttcc agagagacta
    11941 actgcctgct caaggctcga tcatattcga gataaaaata ggtcttaacc cctgtctcat
    12001 aaatataaat aggagtcagg tagcttaagt gattcaattc tttaaggaac cgatttactt
    12061 tttctgggtc ttgttcgcag taggtacagc tcttttttag actatatccc atagccttta
    12121 gagcgtaatg aatagttgtt ggaggacagt tgaattcagc agctatttca gtcaaataag
    12181 catcatcggg atgagtttca atatagatct ttaatttatc tctatcaact ttttcaatta
    12241 atagtggaag ttttcttaaa gttagtgtat tgaaacgttt ttatacagtg ctaaaatttg
    12301 aagtgtagtg cagatatatt tgtaatagta ttatagcaat tctttggaga aggtcgagac
    12361 aagataaaat aggtatcttt gagatataag catgatttac tataaaatta ttgagttatt
    12421 cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt tacaatgcaa
    12481 tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat taaggatata
    12541 gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg tatagatccg
    12601 catataattg gactttgtaa aaagcagatc agaaggatgt ctctatatcc tattttgata
    12661 atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat tgcctatgtt
    12721 gattgtactc aatgttcaaa taattt
//
LOCUS       DAVLHB010000055        11712 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLHB010000055 DAVLHB010000000
VERSION     DAVLHB010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11712
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.055"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            635..1018
                     /locus_tag="VXE36_001789"
     CDS             635..1018
                     /locus_tag="VXE36_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0780038.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            1070..1759
                     /locus_tag="VXE36_001790"
     CDS             1070..1759
                     /locus_tag="VXE36_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0780039.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFSLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVLVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1801..2034
                     /locus_tag="VXE36_001791"
     CDS             1801..2034
                     /locus_tag="VXE36_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780040.1"
                     /translation="MFKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            2185..2796
                     /locus_tag="VXE36_001792"
     CDS             2185..2796
                     /locus_tag="VXE36_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0780041.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            2957..3751
                     /locus_tag="VXE36_001793"
     CDS             2957..3751
                     /locus_tag="VXE36_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0780042.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3748..4383
                     /gene="trmB"
                     /locus_tag="VXE36_001794"
     CDS             3748..4383
                     /gene="trmB"
                     /locus_tag="VXE36_001794"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0780043.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4509..4988
                     /gene="rimP"
                     /locus_tag="VXE36_001795"
     CDS             4509..4988
                     /gene="rimP"
                     /locus_tag="VXE36_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0780044.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            5032..6168
                     /gene="nusA"
                     /locus_tag="VXE36_001796"
     CDS             5032..6168
                     /gene="nusA"
                     /locus_tag="VXE36_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0780045.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6190..6483
                     /locus_tag="VXE36_001797"
     CDS             6190..6483
                     /locus_tag="VXE36_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0780046.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6476..6775
                     /locus_tag="VXE36_001798"
     CDS             6476..6775
                     /locus_tag="VXE36_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0780047.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6792..9584
                     /gene="infB"
                     /locus_tag="VXE36_001799"
     CDS             6792..9584
                     /gene="infB"
                     /locus_tag="VXE36_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0780048.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVALKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9835..10185
                     /gene="rbfA"
                     /locus_tag="VXE36_001800"
     CDS             9835..10185
                     /gene="rbfA"
                     /locus_tag="VXE36_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0780049.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKVQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            10464..11243
                     /locus_tag="VXE36_001801"
     CDS             10464..11243
                     /locus_tag="VXE36_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780050.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            11245..11427
                     /locus_tag="VXE36_001802"
     CDS             11245..11427
                     /locus_tag="VXE36_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780051.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
BASE COUNT         3575 a         2085 c         2636 g         3416 t
ORIGIN      
        1 atgcttactt tttaaatttt ttaacaattc aagatgtttc gatgacaatt caagatttgg
       61 atgaaaaatt ttaaaaaaca atgatatact aaacttgtca aagttgcaac gggtgctact
      121 acattatgtt aaaaatcgct cttgattgat aagctggatt tgttaggaaa ggagtaaata
      181 attatggata agaaaaagat agtttcgact ataatatgta tagtatttct tgtagtgtca
      241 gtagataatt tttttagaga cttaaccccg ttactgttca ttttaaatat tattggcctg
      301 tcttgctttt cagtgctaac atacattaac ataaaagaga tactcttaaa tataagtaaa
      361 tgatgatttg gttagtccta gaaccaatca acttatgttt atcggcttgg cagattttat
      421 gtttgtcatt tgtttgtata gaggtatttc agaaacagaa ttctatcaac aactaatcgc
      481 ttatataggt gtattctctg cttgtttatc acgcttctgc tcatgtgggg cttgaagtat
      541 tataaaaagt agctttctat ccttttctga caggatattt gagtagaagg ctctattaaa
      601 ttgttagtga aataaatgaa tggaggtatt taatatgaaa tacagattat tttttgttat
      661 tttcttgagt agtgtgttgg atattctttt agggacattt ttacaaatct ctatcgtatc
      721 tattgggtgg cttgttcttt acagtggttt gtttgaagca ggagttttcc ttcttgctaa
      781 taaaggggtg gcggtaaaaa tcaaggaagt agatattcga aatcgcttta aatttatttt
      841 tggaaaaacc ttatggtttc aaattctttt gctcatcttt ttgataatca aactttatct
      901 tggtttggat gcgaggttga ttttattcta tggacatatt ttcattgtct ttaatgcctt
      961 aatgtatcta ttatctagta gtcaggttag ccttaaaaaa aacaaactgt cttcttaatc
     1021 ttacagcagt agagcctgac aaggtgaggt catagtaggg aggatttcta tgaaaaagta
     1081 tcaacttcta ttcaaaataa gtgcagtctt ctcttactta tttttcgtat ttagtctttc
     1141 tcagctgacg cttatcgtcc aaaactattg gcaattttct tctcagatag gcaatttatt
     1201 ctggattcaa aatatcttga gtttactttt tattggagtc atgattgtgg ttcttgttaa
     1261 gacaggccat ggttatctct tccgcattcc aagaaaaaaa tggctttggt attcgatttt
     1321 gacagtatta gtgctagtgt tccagatctc ttttaacgtt cagacagcta aacatgttca
     1381 gtcaactgcg gaaggttggg ctgtattgat tggttatagt gggactaact ttgcagagct
     1441 aggtatttat atagccctgt tctttctggt tccactgatg gaagaattga tttatagagg
     1501 attactgcaa catgctttct ttaagcattc gcgatttggt cttgatttgc ttcttccttc
     1561 tattttattt gctctccctc atttttcaag cctgcctagt ctgttagata tcttcgtctt
     1621 tgcaacagtt ggaatcatct ttgctggttt gacccgctat accaagagca tttatccatc
     1681 ctatgcggtg catgtgatta ataatattgt agcgaccttc ccgtttttgc tcacttttct
     1741 acatagggtc ttggggtaaa aaaacaaaag gcttgctttt cagccataga ggaggtcatc
     1801 atgtttaaac acttattttt cctagattcc aaaactttag atcggttgac accctatatt
     1861 ctagtcttgg cttctgacac cattgctttt aatgtttttg tgctaacctt tgtatctgcg
     1921 gtggttttta atttcctaaa ttccatgcta gctttaatgg ctatattcat aggggctggc
     1981 tatgtggtcg gattttggtt actaatactc aatgaaaatc aaagagcaaa ctaggaaact
     2041 agccgcaggc tgtacttgag tacggcaagg cgacgttgac gtggtttgaa tttgattttc
     2101 gaagagtata aaatggtttg ttttggaaag gctagaacta aagaatgacg tgtaggaagt
     2161 ctgtttgttg aggaggataa ttttatggag ttttttgata aatttcatgc cttgtgtttt
     2221 ggatttttag tactaataat tgtcattaca gttccttata cgattaacca tgggggtttt
     2281 tttcaaaatg aatctgcatt gattcttgta agtcttcttg taacctcgct gagtgttgct
     2341 tatgctagaa agtttgaaat gatttctttt gggatgttaa gcaagaaaca acttttgctt
     2401 ttcattgcaa tctttcttct aagtgtactt gagacgctgg tttatattca tttcttcgct
     2461 gtttcttctg gctcaggggt ccaacacttg gcggaagtca gcagaggaat ttccctgtct
     2521 ttgattttaa ctacctcagt ttttggcccc atccaggagg aactcatttt cagaggactt
     2581 cttcaaggtg cggtttttga caattcttgg ttagggcttg tgctaacttc ctctctcttt
     2641 tctttcatgc atggaccttc taatgtccct tcgtttattt tttatctact tgggggtttg
     2701 ttgctgggct ttgcttataa aaagagtcaa aacctatggg tttctactct agtccatatg
     2761 ctttacaaca gttggccact cttatattat ttataaaaat gatgaaaagg taagcagaag
     2821 acggtgctta cctttttcaa gctataatga tacccaagcc aatccagagg cttttctttg
     2881 agaatcgggt tagagtggtt gacgaatagg ccaaaaacta gtagaatagt aaggaaactt
     2941 tatacggagg aaagaaatgg atttgggtga taatgagcta acactgactc ccatacctgg
     3001 gaaaagtggc aaggcttata tgggtagcta tcctgatggg aagcgcatct ttgtaaaaat
     3061 gaacacctct ccaatcctac ctggtctagc tagagaacaa attgctccac aattattatg
     3121 gagtcgtcgt ttggcagatg ggcgtgatat gtgtgctcaa gaatggttga caggcaagat
     3181 attgaccccc tatgatatga atcgtaagca aatcgtcaat attttaaccc gtcttcatcg
     3241 ctcacgtccg ttgatgacac aattgagtcg tttgggctat gccatggaaa cacctgtaga
     3301 tttactacag tcttggcagg aaacggctcc agatgctttg cgtaaaaatc attttatcag
     3361 tgaagtgatg gctgatttac gtcagactat tccaggattt agagaggacc atgcgaccat
     3421 tgtccatgga gatgtacgac atagtaattg gattgagaca gatagtggct tgatttattt
     3481 agtagattgg gattcggttc gcttgaccga tcgcatgttt gatgtggccc atatgctctg
     3541 ccattatatt tcagaacatc agtggaagga atggttgacc tactacggtt acaagtacaa
     3601 tcaaacggta ttaagtaaat tgtattggta tggtcaattg tcttatttga gtcagatttc
     3661 caagtattat atgaaccaag atttagaaaa tgtcaatcgg gagattcatg gtttgcgtca
     3721 tttccgagac aagtatggaa agagaagatg agagttagaa atcgtaaagg ggcaacagaa
     3781 ttactagagg caaatcccca gtatgtggtc ctcaatccct tggaagccaa ggcaaaatgg
     3841 cgggacttgt ttggcaatga taatcccatt catgtggaag ttggaagtgg aaagggtgcc
     3901 tttgtttcag gtatggccaa gcaaaaccct gacatcaact atatcgggat tgatattcaa
     3961 aagtctgttt tgagctacgc tttggacaag gtgcttgaag ttggagtgcc taacatcaag
     4021 ctcttgtggg tagatggttc tgacttgact gactactttg aagacggtga gattgatcgc
     4081 ttgtatctga acttttcaga tccatggccg aaaaaacgcc atgaaaagcg tcgtttgacc
     4141 tacaagacct ttttggacac cttcaaacgt atcttgcctg aaaatggaga aattcatttc
     4201 aagacggata accgtggctt gtttgagtac agtttagtga gcttttctca atatggcatg
     4261 aaactcaatg gtgtctggct agatttgcat gccagtgatt ttgaaggcaa tgtcatgaca
     4321 gaatacgagc aaaaattctc aaacaagggg caagttatct accgagttga ggcagaattt
     4381 taagagatag cctaaaatta ggctgtacaa gtgcttttgc tttacataag ttggcaaacg
     4441 tgctatactg atagtaagaa tatgaaaagt gaggcgggga aatatcttcg cctcttgctt
     4501 atgaggaggt ggacgcaatc gcaacaatcg tagaattagt cagagaagtt gtagaacctg
     4561 tcatagaagc tccttttgaa ctcgtggata tcgagtatgg aaagattggc agtgacatga
     4621 ttctcagtat ttttgtagat aaacccgaag gaattacctt gaacgacacg gcagacttga
     4681 cagaaattat cagtcctgtc ctagacacca tcaagccaga tcccttccca gaacaatatt
     4741 tcctagaaat taccagtcca ggcttggaac gtcctttgaa aaccaaggat gccgtcgctg
     4801 gagcggttgg aaaatacatc catgtcggac tctaccaagc catcgataag caaaaggtct
     4861 ttgaaggaac tttgttggcc ttcgaagagg acgagttgac tatggaatat atggacaaga
     4921 cgcgtaagaa aaccgtccga attccataca gtttagtatc aaaagcacgt ttagcagtta
     4981 aattatagaa aaagaaagga tagcttttga ggattcaaaa gtgaagaaaa catgagtaaa
     5041 gaaatgctag aggccttccg cattttggaa gaagacaagg gaatcaaaaa agaagatatc
     5101 atcgacgcag tagtagagtc gcttcgttcc gcttatcgca gacgctatgg tcagtcagac
     5161 agcgtagcta ttgacttcaa cgaaaaaaca ggtgacttta cagtttatac tgtccgtgaa
     5221 gttgttgatg aagtatttga tagccgtttg gaaatcagct tgaaagatgc tcttgccatt
     5281 aattcagctt atgaacttgg agacaaaatc aagtttgaag aagcaccagc tgagtttggt
     5341 cgtgtagcag cccaatctgc caaacaaacc atcatggaaa aaatgcgcaa gcaaacacgt
     5401 gccatcactt acaatactta caaagaacat gagcaagaaa tcatgtctgg tacagtagaa
     5461 cgctttgaca accgctttat ctatgtcaac cttggtagca tcgaagccca attgtcaaaa
     5521 caagaccaaa ttcctggaga agtttttgct tctcatgatc gtatcgaagt ttatgtttac
     5581 aaggttgaag acaaccctcg tggtgtgaac gtctttgtta gccgtagcca tccagaaatg
     5641 atcaaacgtt tgatggagca agaaattcca gaagtttatg atggaactgt tgaaatcatg
     5701 agcgtggctc gtgaagcagg tgaccgtacg aaggttgctg ttcgtagcca caatccaaac
     5761 gtggatgcta tcggtacaat cgttggacgt ggtggtgcta atatcaagaa gattactagc
     5821 aaattccacc cagctcgtta cgatgctaaa aatgaccgca tggtaccaat cgaagaaaat
     5881 atcgatgtta tcgagtgggt agcagatcca gctgaattta tctacaatgc catcgctcct
     5941 gctgaggttg accaagttat ctttgatgaa aacgacagca aacgtgcctt ggtggttgtt
     6001 ccagataaca agctttctct tgccattggt cgtcgtggac aaaacgtgcg cttggcggct
     6061 cacttgactg gttaccgtat cgatatcaag tctgctagcg aatttgaagc catggaagac
     6121 gctgcttcag tagagttgga agtagaaaac gatactgtag aagaataaaa gctgctagag
     6181 gagggaaaga tgaaaacaag aaaaatccct ttgcgcaagt ctgttgtgtc taacgaagtg
     6241 attgataagc gtgatttgct ccgcattgtc aagaacaagg aaggacaagt ctttattgat
     6301 cctacgggca aggccaatgg ccgcggcgct tatatcaaac tagacaatgc agaagcccta
     6361 gaggcgaaaa agaagaaggt ctttaaccgc agctttagca tggaagtgga agaaagcttt
     6421 tatgacgagt tgatcgctta tgtggatcac aaagtgaaaa gaagagagtt gggacttgaa
     6481 taagcaaaag ataagtaatc tcttggggct tgctcagcga gcagggcgca tcatatcggg
     6541 tgaagaattg gtggtcaagg ccattcaaga cggcaaggcc aagttggtct ttctagctca
     6601 tgatgctgga cccaatctgg ccaagaagat tcaagataaa agtcattatt atcaagtaga
     6661 aattgtaacc gtgttttcaa cactggaatt aagcatagca gtcgggaaat cgagaaaggt
     6721 tttggctgta acagatgctg gatttacaaa gaaaatgagg tctcttatgg aatagaagag
     6781 gaggacatga tttgtctaag aaaagattgt acgaaatcgc aaaagaactt ggaaaagaaa
     6841 gtaaagaagt tgtagcgcgt gcaaaagagt tgggcttgga tgtgaaaagc cactcatcaa
     6901 gtgtggaaga agctgtcgct gcaaaaattg ctgccagctt taagcctgca gctgctccga
     6961 aagtagaagc aaaacctgca gcaccaaaag taagtgcaga aaagaaaacc gaaaaatctg
     7021 agccagctaa accagctgta gctaaggaag aggcaaaacc ggctgagcca gttgctctga
     7081 aaacagaaaa agtagcagcg aaaccgcaaa gccgtaattt caaggctgag cgtgaagccc
     7141 gtgctaaaga gcaggcagaa cgacgcaagc aaaataaggg caataaccgt gaccaacaac
     7201 aaaacggaaa ccgtcagaaa aacgatggcc gtaatggtgg aaaacaaggt caaagcaacc
     7261 gcgacaatcg tcgctttaat gaccaagcta agaagcagca aggtcagcaa aaacgtagaa
     7321 atgagcgccg tcagcaagag gacaaacgtt caaatcaagc ggctccacgt attgacttta
     7381 aagcccgtgc agcagcccta aaagcagagc aaaatgcaga gtacgctcgt tcaagtgagg
     7441 aacgcttcaa gcagtatcag gctgctaaag aagccttggc tcaagctaac aaacgcaagg
     7501 aaccagagga aatctttgaa gaagcggcta agttagctga acaagcacag caagttcaag
     7561 cagtggttga agtcgtccct gagaaaaaag aacctgcagt ggatacacgt cgtaaaaaac
     7621 aagctcgacc agacaaaaat cgtgacgatt atgatcatga agaagatggt cctagaaaac
     7681 aacaaaagaa tcgaagtagt caaaatcaag tgagaaatca aaagaatagt aactggaata
     7741 acaacaaaaa gaacaaaaaa ggcaataaca agaacaaccg taatcagact ccaaaacctg
     7801 ttacggagcg taaattccat gaattgccaa cagaatttga atatacagat ggtatgaccg
     7861 ttgcggaaat cgcaaaacgt atcaaacgtg aaccagctga aatcgttaag aaacttttca
     7921 tgatgggtgt catggccaca caaaaccaat ccttagatgg ggaaacaatt gaactcctca
     7981 tggtggatta cggtatcgaa gccaaacaaa aggttgaagt ggataatgct gacatcgaac
     8041 gtttctttgt cgaagatggt tatctcaatg aagatgaatt ggttgagcgt ccaccagttg
     8101 ttactatcat gggacatgtt gaccacggta aaacaaccct tttggatact cttcgtaact
     8161 cacgtgttgc gacaggtgaa gcaggtggta ttactcagca tatcggtgcc taccaaatcg
     8221 tggaaaatgg taagaagatt accttccttg atacaccagg acacgcggcc tttacatcaa
     8281 tgcgtgcgcg tggtgcttct gttaccgata ttacgatctt ggtcgtagcg gcagatgacg
     8341 gggttatgcc tcagactatt gaagccatca accactcaaa agcagctaac gttccaatca
     8401 tcgtagccat taacaagatt gataaaccag gtgctaaccc agaacgcgtt atcggtgaat
     8461 tggcagagca tggtgtgatg tcaaccgctt ggggtggaga ttctgaattt gttgaaatct
     8521 cagctaaatt caaccaaaat atcgaagaat tgttggaaac agtccttctt gtagctgaaa
     8581 tccaagaact caaggcagac ccaacagtgc gtgcaatcgg tacggttatc gaagcgcgct
     8641 tggataaagg aaaaggtgcg gtcgcaaccc ttcttgtaca acaaggtacc ttgaatgttc
     8701 aagacccaat cgttgtcgga aataccttcg gtcgtgtccg tgctatgacc aacgaccttg
     8761 gtcgtcgtgt taaagttgct ggaccatcaa caccagtctc tatcacaggt ttgaacgaag
     8821 caccgatggc gggtgaccac tttgccgttt acgaggatga aaaatctgcg cgtgcagcag
     8881 gtgaagagcg tgccaaacgt gccctcatga aacaacgtca agctacccaa cgtgttagcc
     8941 ttgaaaacct ctttgatacc cttaaagctg gggaactcaa atctgttaat gttatcatca
     9001 aggctgatgt acaaggttct gttgaagccc tttctgcctc acttcaaaag attgacgtgg
     9061 aaggtgtcaa agtgactatc gtccactcag cggtcggtgc tatcaacgaa tcagacgtga
     9121 cccttgccga agcttcaaat gcctttatcg ttggtttcaa cgtacgccct acaccacaag
     9181 ctcgtcaaca agcagaagct gacgatgtgg aaatccgtct tcacagcatt atctacaagg
     9241 ttatcgaaga gatggaagaa gctatgaaag ggatgcttga tccagaattt gaagaaaaag
     9301 ttattggtga agcggttatc cgtgaaacct tcaaggtgtc taaagtggga actatcggtg
     9361 gatttatggt tatcaacggt aaggttgccc gtgactctaa agtccgtgtt atccgtgatg
     9421 gtgtcgttat ctatgatggt gaactcgcaa gcttgaaaca ctataaagac gacgttaagg
     9481 aagttacaaa cggccgtgaa ggtggattga tgatcgacgg ctacaatgat attaagatgg
     9541 atgatgtgat tgaggcgtat gtcatggaag aaatcaagag ataagatttt ttgctccttt
     9601 cttaggtggt gagggacgca agcaaaccga tggtttcatt gcttattttt gagcctaggg
     9661 tctcaaaaat cccctgtgat gggactgata aatcagttcc atcactttca ccacggcgaa
     9721 agaagcagat gacttcaaat tgaacttcgt ttcaatttaa actgaaaatc aagaagttta
     9781 aaatagctag gtctgctggc ctagcttttg gttcaaagta gagaaaggaa tatcatggca
     9841 aatcatttcc gtacagatcg tgtgggcatg gaaatcaagc gtgaagtcaa tgagattttg
     9901 caaaagaaag tccgtgatcc acgtgtccaa ggtgtgacca tcacagatgt tcagatgctg
     9961 ggtgacttgt ctgttgccaa ggtttattac accattttga gtaaccttgc ttcggataac
    10021 caaaaagtcc aaatcgggct tgaaaaagca actggtacca tcaaacgtga acttggtcgc
    10081 aatttgaaat tgtacaaaat cccagatttg accttcgtca aagacgagtc catcgagtat
    10141 ggaaacaaga ttgacgagat gctacgcaat ctggataaga actaaagaag aggggttgcc
    10201 cctctttttt ggtggaggaa aataggttga atttgaaatg gaaaaatatt cttttataat
    10261 agattgaaac tagaatagta cgcctctact tctaaaatat tgttagaaat cgatttgact
    10321 gtcctgatcg atttgtcctg ttcttgtttc gttttaatat aaaaaaggga ttctgtattt
    10381 tttaatgtta tctaattaga aaatgctttt tttgtaggaa atataatatg ataaggtgta
    10441 aaaaagaaat aaggagtttg tatatggctg aacaagactt agctatgcaa gtattgcaac
    10501 aagtggtgaa actacctgtt gttaaggttg atcgttcgaa atttttagtg gataagtttt
    10561 ccaaagaatt ggatccaaaa gatattccta ccttattgga acaaggtaca acgactcttc
    10621 tatctcaaga aatattagat cgtgtagcta atgcttgtat tcgggacaat gtattattag
    10681 cgagtgggac ttctgttttg gcaggattag ctggagggct tgctatggca attaccattc
    10741 cagctgatgt ggctcaattt tatgctttct ctctgaaatt ggctcaagaa ttaggttata
    10801 tttatggtta tgaggatctt tgggcttcac gcgaggagtt gagtgaagat gctcaaaata
    10861 ccctcttgct ttatctaggc gtaatgttag gggtgaatgg aaccgctgct ttgctacgtg
    10921 ctggtggtat aacaattgcc aaacaggtaa tgaaaacagt gcctaataaa gctttaacaa
    10981 agacgctttg gtaccctatt ttgaaaaaag tcttaagaat atttggtgtg aatcttacca
    11041 agggagggct ggccaaagga atagggaaat ttattcctat cttgggtggt atcatttcag
    11101 gtggtttaac ctttgcaact atgaaaccaa tgggggaaag cttgcagaaa gaattatcca
    11161 agctagtcaa ctatagtgaa gttcaatatc aagaagatgt tgaaacaatc cgaaaagagg
    11221 ctgaaatcat caaaggagag taatatgaat cctatcaaag cttttgctaa aatttatggt
    11281 aattactttt tgaccgtgca aggtgtaaaa gtgatgaaaa cgataaagaa agctgaccat
    11341 gtcgttgttg gtctggggaa actttttatt gccgacaagt taatggatac ggctcggtgg
    11401 ctcattaagc cagaggagag agaatgaaat ttttttggtc ttcttgctat tctttttatc
    11461 aaaccgatta ttgggattgt gaaattcttt tggatgatca tctcttttgc agtccaattg
    11521 ctgttttaca agatagtgtt taagatattg gattggctct ttaaacttat ctagatggta
    11581 atccaagttg cagagaacta gcaggaactc cactgctagt tttttattct ctttccatat
    11641 ggtataatat aagcagtaaa atcattttat actcttcgaa aatctcttca aaccacgtca
    11701 gcttcacctt gc
//
LOCUS       DAVLHB010000056        11588 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLHB010000056 DAVLHB010000000
VERSION     DAVLHB010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.056"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(136..1272)
                     /gene="dnaJ"
                     /locus_tag="VXE36_001803"
     CDS             complement(136..1272)
                     /gene="dnaJ"
                     /locus_tag="VXE36_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0780052.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1545..1901)
                     /locus_tag="VXE36_001804"
     CDS             complement(1545..1901)
                     /locus_tag="VXE36_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0780053.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(1903..3726)
                     /gene="dnaK"
                     /locus_tag="VXE36_001805"
     CDS             complement(1903..3726)
                     /gene="dnaK"
                     /locus_tag="VXE36_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0780054.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4206..4730)
                     /gene="grpE"
                     /locus_tag="VXE36_001806"
     CDS             complement(4206..4730)
                     /gene="grpE"
                     /locus_tag="VXE36_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0780055.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPGDDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4757..5791)
                     /gene="hrcA"
                     /locus_tag="VXE36_001807"
     CDS             complement(4757..5791)
                     /gene="hrcA"
                     /locus_tag="VXE36_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0780056.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(5955..6464)
                     /locus_tag="VXE36_001808"
     CDS             complement(5955..6464)
                     /locus_tag="VXE36_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0780057.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7072..9405
                     /locus_tag="VXE36_001809"
     CDS             7072..9405
                     /locus_tag="VXE36_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0780058.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYSRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9418..10881
                     /locus_tag="VXE36_001810"
     CDS             9418..10881
                     /locus_tag="VXE36_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0780059.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTFEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            10881..>11588
                     /locus_tag="VXE36_001811"
     CDS             10881..>11588
                     /locus_tag="VXE36_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0780060.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRI"
BASE COUNT         3566 a         2257 c         2235 g         3530 t
ORIGIN      
        1 caaaaagcaa actaggaaac tagccacggg ctgctcaaaa cactgttttg aggttgtgga
       61 tagaactgac gaagtcagta accataccca tggcaaggca acgctgacgt ggtttgaaga
      121 gattttcgaa gagtattatt ctccatcaaa ggcatctttt atatggtcaa agaagccttt
      181 tttctttgga tttactttca agtcaccagc agccgcgaat tctttcaagg ctactttttg
      241 gcggtcgttc aagcctgtcg gtgttacgac attaacagta acgtattggt caccaactgc
      301 accgccacga aggctcggtg cccccttact acgtaggcgg aatttcttac cagtctgagt
      361 tccctctgga ataaccaatt caacatcacc gtgaacagtt ggaatatcta ctgtatcacc
      421 aagagccgct tggacaaagt tgaggttgag attgtagaag atagtcgttc cttcacgttc
      481 aaacttgtcg ctagcttcca cagaaactac tacatacaag tcaccataag gtccaccgtt
      541 aaagcctgct tcaccttgac cagcgaggcg aatttgttga cctgtttcca caccagcagg
      601 gattttcaca tgtacgctat gagcttgttt ctcatgacct gttccatgac aggttgtaca
      661 tggatatttg atttcttttc cttggccgtg acagacatca caggttactt ggcgacgcat
      721 cataccaaga ggagtctgcg tatcgacatt aatgacacca gcgccatgac agcgtccaca
      781 agtgactgga cttgtccctg gcttagcacc agagccatta catgtacgac agccagcttc
      841 acgatgatac ttaacttcct tctcagttcc gaagatagct tcttcaaagg tcaaattgac
      901 acgatactgg agatcatctc cttggcgagg agcgtttgga ttgcgcgaag aaccgcctcc
      961 gccgaagaaa cttgagaaaa tatcctcaaa accaccgaag ccacctgccc cattgaaacc
     1021 gccgaaacca ccatctccac caaaaccacc attggcgcct gcagcaccat actggtcata
     1081 ggcagcacgt ttttggtcgt cactcaaagt ctcataggct tcttgaactt ccttgtactt
     1141 gtcctcagca ccaggctcct tgttgatatc tgggtgatat tttttggaaa gcttacgata
     1201 agcctttttg atttcgtctg ccgaagcgtt tttggatacc cccagacgat cataaaattc
     1261 agtattgttc atacaagata ccaagaccgt aaaattcgac tgaaaaatag gaaatctgac
     1321 gctggagcga cgctcctaga cagatttctc ttttttccga gaatttaggt cgggttcaat
     1381 tcctttcttt tatattgatg agataatact ccagccactc ggccctatcc ctttttatcg
     1441 aaaaacagag gctgggttgc aacctctgca aataagtaaa ttaactttat tttgatttta
     1501 aatatcctat aagtacagaa atatttatat atttttgtct cttcttagta tttgcctata
     1561 taattccaat tgatcataag aaatacaact actgtccaaa tcataccaat tatgaacggt
     1621 attacaaatt tatatgtttg tatttctaat gatatcatag ctgataccat cgctgataca
     1681 aatgcagaca acaatactga agtaacaaaa ttccttaccg cttcatcatt tttgacacaa
     1741 ctatcatgct cagctaatat aatttctcta tatatagtca aacattctac tggaatatta
     1801 tctataaaac cttttgctgc ttcatagttg tcagcttgat tacaaaaatc attataaact
     1861 tttcgtgtat tttttagata ctcatcatcc aatacactca tcttattttt ccgtaaactc
     1921 tccgtctacg acgtcatcgc ctgcgtttcc tgttgcttgt gcgccttctg ctccttcttg
     1981 agcttgttgc gctgctgcgg cttgttcgta gagtttcaca gcaaggcctt gagctttttc
     2041 gttcaacgct tcaagtttcg ctttcatgtc gtccaagttg ttgtcttctt gagctttctt
     2101 aaggtcatca agggcagctt gggcagcgtc acgttctgcg tcgaagcctt taccttcagt
     2161 ttccttgatt gtcttttcag tcgcaaagat tgcttggtct acttcattac gaaggtctac
     2221 ttcttcttta cgtttcttat cggcttcagc gtttgcttct gcatctttca tcatgcggtc
     2281 gatttcttcg tcagtcaaac ctgagttcga ttggatgaca atagtttgtt ctttttgagt
     2341 tccaaggtct ttggccttaa cagacacgat accgttcttg tcgatgtcaa atgttacttc
     2401 gatttgagga attccacgag gtgcagctgg gatatcagtc aattggaagc gtccaagagt
     2461 cttgttatct gctgccattg ggcgttcacc ttgaagaacg tggatatcaa cggctggttg
     2521 gttgtctgct gctgttgaga agacttgtga tttagatgtt gggattgtag tgttgcgatc
     2581 gataagtttt gtaaatactc cacccattgt ttcgatacca agtgacaatg gcgttacatc
     2641 aagaaggaca acgtccttga catcaccagt aatcacacca ccttggatag ccgcacccat
     2701 agcaactact tcatcagggt ttactgattt gtttggttct ttaccagttt cagctttaac
     2761 agcttcaaca acggcaggga tacgagttga accaccaaca aggataactt cgtcgatttc
     2821 tgacaagctc aaacctgcat ctgaaagggc ttgacgaact ggaacttttg tacgttcaac
     2881 aaggtcacga gtcaaatcat caaatttcgc acgagtcaaa gtcatttcca agtgaagagg
     2941 tccagcctca cctgcagtga taaatggcaa gctgatttgt gttgaagtta caccagaaag
     3001 gtctttcttc gctttttcag ccgcatcttt caaacgttgc attgccatct tgtcagtaga
     3061 caagtcgata ccgttttctt tcttgaattc tgctaccaag tggtcaatga ttttttggtc
     3121 aaagtcgtca ccaccaagtt tgttgtcccc tgcagttgac aatacgtcga agacaccgtc
     3181 acccaattca aggatagaga cgtcgaatgt accaccacca aggtcaaata ccaagatttt
     3241 ttcttctttg tcagtcttgt ccaaaccata agcaagagct gctgcagttg gttcgttaac
     3301 aatacgttct acttcaagac cagcaatttt accagcgtct tttgttgctt gacgttgagc
     3361 gtcgttgaag taagctggaa ctgtgataac agctttggtt actttctcac caaggtagtc
     3421 ttcagcgtag cctttcaagt attgaaggat catagctgag atttcttgtg gagtgtattc
     3481 ttttccattt gcagaaactt tttcagaagt tcccatctta gatttgatag agataactgt
     3541 atctgggttt gtgactgctt gacgttttgc agcatcacca acgatgattt ctccgttttt
     3601 gaatgagact acagatggag ttgtgcggtt cccttctggg tttgcgatga ttttgctttc
     3661 agttccttca agaactgcaa ctgctgagtt tgttgtacct aagtcaatac cgataatttt
     3721 agacatgtgt ttttctcctt gttagttaat tttctatttt tctttttgat actcttctta
     3781 agtggcgacg ccgtcagagc ttgacttcgt caatctcttt gactaaactt tgagcctaag
     3841 gtctcaaaat ttgcgcaaat agcaccacgg cgaagagtat cgtctttggt tcgcttcgct
     3901 cactattaca aagccaaaca tattttatct ttcttcatag tttattgtcg tttcggacaa
     3961 gttttctatt atgtaaattg cgacacgagg agtcgaaatc gattttattt cgacgacgag
     4021 ttagtaagga agctaggcaa acgtcatagc gattgccgtt ttctgacgag ttgctttagc
     4081 taccgtcaga attgccgaat cgaacacgcc ctaagctctg agtaaaaaag atagattttc
     4141 ttgtgttcat cgaacacttc gtcaatctcc tatttttact gcgagctttt tacgagcttt
     4201 gtatcttagt tatacaccac taccattgct gggcgtagga tgcggtcatg gagtttgtag
     4261 cctttttgaa agacttgggc gatggtatct actgggtgtt catcgtctcc tgggagagtt
     4321 tggatggcca tatggtagtt atggtcaaat tcgccatctg ctgcgatttc ttcaattcct
     4381 tcttctttca aagcgtgaat caagctttct tgcaccatcg ccaagccctt cttcacatca
     4441 tctgtcaaac cttcaactgc aagtgcacgc tcaaggttgt caagagatgg taagattgct
     4501 tttgccaagt cctggctacg ataacgttgc aagttttgac gttcttcatt ggcacggcgt
     4561 tggatatttt gcatttctgc atgagcgcga agatatttgt tttcgaactc atctgcacgt
     4621 tcatttgcca agtccaactc agacttttca ggagttgttt cttcagctgt ttccacaact
     4681 tcctcttctt gaacttcttc tacttcttca ttttttatat cttgggccat gttcgcctcc
     4741 tttaatgatt tcaatcttaa tgtacttcgt aatgattact gctgaggtag cggtaaaaat
     4801 ctgtcaactt catggtcaaa acacggttga ccacattgat ttgattgatt agctgttggt
     4861 aatccagatt aactggaccg ataatggcta gaattccaac tccccgataa ggaatgagga
     4921 acttactact aatcaccgct aggtcagcta aacaggactc ttgaccgtct gcaacacgaa
     4981 cattttgcat ctgatcctca cgcaacccct cacgaatctc caaggccacc ttttgcggtt
     5041 ggtcaaagaa ctgataggct gctagattgg caaaattcaa gagattgacc ttgcccgcca
     5101 tcacaatgtt ttcgttgaac atttccttaa agatgtgttc aaagagatcg atgacattat
     5161 ccgttgttgt aaagtaacgc tgtataatct gcggaatctc cgtccgaatc ttgtagtgaa
     5221 tatctaaaac ggtgtgaccg aggaaacgtt cctgaatgat gctcttcagt ttcagcaaat
     5281 cctcctgcaa gaagttcctt ggaatcagaa actgactagt aaccgttcgc gactcgtcta
     5341 gggtaaatac cgccaaggct gtatgttgcc ccaaaacaac gatatcaaag gctgtcaaac
     5401 gttgcctgct cggctcaaca tccagtgcca ctaccgtaca gccactcagg tctgttagca
     5461 agttagcagc ctcttgcaga atatcctcca atttgaagaa ttcctgatca aaggctttga
     5521 caatctcata tacctcattt tcagccagtc ggtcaaaatc cagtgagtgt ttcacatagt
     5581 actgaaaacc agcaacactt ggcatccgac cgcttgaagt atgagccttc tcaagcaacc
     5641 cttgtttttc tagttccgcc atgtcattac gaatggttgc actgctagag ttaatagact
     5701 cttgcaaggc ttttgatccg acaggttcgt gcgttttggt aaagatgtca ataatcagat
     5761 ttaaaatatc ctgctgacgc tctgtaacca tctcatcact cctctctgtc tgatcaatta
     5821 gcactcaatg catccaagtg ctaacttatg attctattat acacccttag aagagaatgt
     5881 caagacaaaa actcaaaaaa ttagcactct tttataaaga gtgctaaaaa tcaatctgaa
     5941 gacctagaac cttgctattc atctactcgg tatttccttt ttagtctgaa ataaccatga
     6001 attagataag aaatcagaaa agcatataaa acaaaaataa gaaagaaaga catagaaaga
     6061 tcctctctaa acaaactcat acaaacaaca agaccaccta agaaagtagc tatacaggaa
     6121 cgaagtctag atcgcataac ttcccatttg agccccttac tcatatagac ttgatcctct
     6181 ggaagtaaat cagaagacga tttacgaaga atcgaacaag aacctgctcc tatcaattcc
     6241 caacctctat ctctaaaatc ttgcagttca cgcttatgct ctttaagaaa tctagaatca
     6301 tagatacgat agataacatc gtccggttga ccttgctcaa aatagaacaa accaaaacga
     6361 ctagttctat acctccaacc tttcaaatgc atctcatgta aatattcttc tttcttgtcc
     6421 aaatcaacaa tggtgaaaat ccgaaattct actctgctat tcattgtctt accccaaaat
     6481 tagaaaacat gcctagcgtt atttattaga taattctttc cacttttgac tcaatctcca
     6541 aaaaatataa gaaatctgaa tcgcaaaaac tatcaataaa acccaatcta ttatgaaaat
     6601 caaaaacact tcccaactga aagaactacc tccagtgaca aactttgaga aaaccggtag
     6661 tagagctaaa aagagaagca aaataggaag catccgcatt gttaaaatcc ttttggcata
     6721 aaaaaatctt tatttaaacg aaaatattat ggcaaaattt acgccagttt ttgaacggct
     6781 gatgtagata ttttatactt tcaaaatgtt taaatgtgat tatttatttt tgaaaaatag
     6841 ctcaccagcc cgactgaaag tgcttataga atgataataa gtcgcctgcc gaaaacagcg
     6901 aaaaatagca gtgttatgcg gagataatct gacgcgatgc gaaagtatat tgcatactta
     6961 ttttcaacaa tttagcagag tatttttata agtgtgatat aatagaagta taatttgttc
     7021 tgatagttta ttttatggag aagtagattt ttagaatgcg gaggattcaa tatggttgag
     7081 tttataaagt ctaagaaaga aatgagtgag gaggatatta aagcaaattt catcactcct
     7141 gctattgtat ccaaaggatg gaaaaatggt gagcatatcg cttacgaaga atacttcact
     7201 gatggtcgaa ttgaagttag aggagataag gctcgtcgta aagaaggaaa aaaatcagac
     7261 tattcactgt attaccaatt tggaactcga attgcaattg ttgaggcaaa ggataataaa
     7321 cacagcgttc gagcaggatt acaacaagct attgaatatg gagagatttt agatgttcca
     7381 tttgtttatt cttcgaatgg tgatggcttt attgaacacg accgtatcac gagagaagaa
     7441 cgtgagctgg agttagacga attccctact cgtgaagaat tattttctcg tatgacgaag
     7501 gaaaaaggat tgacgtacga aattacagaa gctatctcaa ctccatacta tacagacgcc
     7561 ttctcaatga aaacgccacg ctattatcag caaatagcta tcaaccgtac tattgaaaca
     7621 gttgccagag gacaaaaacg agtaatgttt gtgatggcaa caggaacggg gaaaacgttc
     7681 atggcttttc aaattattca tcgccttcga aaagctggtt tggctaaacg agttttattc
     7741 ttagcggata gaaacatctt agtagaccaa acgatggctg aagactttaa gccattcgaa
     7801 aaggtaatga cgaaaattac accaaaactt ttgactgctc ctgaaaaatt aaattctttt
     7861 gaaatttatc tagggcttta tcagcaacta actggtgaag atggaactga aacacattat
     7921 caaaaatttg acaaagactt ctttgattta atcgtaattg atgaagcgca ccgtggttca
     7981 gctaaggaaa acagtaactg gcgtaagata attgattatt tcagttctgc gacacagatt
     8041 gggatgaccg ctactcctaa agaaaccaag aatgcttcca atacggaata ctttggtgag
     8101 ccaatctata cttatagttt aaaacaggga atcgaggatg gttttttggc tccatatcgt
     8161 gttatgaggg ttaatttaga tgtggatgtg gatggttatc gtccagaaac tggaaaagtt
     8221 gatgctaacg gacaattaat agaagatagg tactacagca ggaaagattt tgataaaacc
     8281 attgtcattg atgacagaac gcaaagagtt gccaagtttg tttctgatta tatgaagcaa
     8341 aacaatgcac gatttgataa aacaattgtt ttttgtgttg atattgacca tgccgagcga
     8401 atgcgtgctg cacttgtaaa agagaatcta gacttagtcc aagaagacta tcgttatgtc
     8461 atgcaagtaa ctggtgacaa cgctgaagga aaagctcaac tggataactt tatggatgtc
     8521 aattctaatt ttcccgctat tgtaacaacg tctaaattat taacgacagg agttaatgct
     8581 aaaacatgtc gtttgattgt tttagactct aatatccaat ccatgactga atttaaacaa
     8641 attattggtc gtggcacacg tctttatcct caaaagggga aagaattttt tacgattatt
     8701 gattttcgaa atgttaccaa tttgtttgct gaccctgatt ttgatggtga gccagtgaag
     8761 gtgctggaaa caggtgcgaa aacagtcagt ggttctacgc ccggtttcgt agatgaggaa
     8821 ggtgacccag tagaaaaata tatcgttaca gacaagcagg ttaccattct taattctact
     8881 gttcaagtat tggatgaaaa cgggaaactg attaccgaaa gcctgaccga ctacactcgg
     8941 aagaatatct taggtagcta cgccactttg aacgatttta tcacagtttg gcatacggcg
     9001 gataaaaaga agcttatctt agacgaactt tataaaaaag gagtttatct agatgctatt
     9061 cgagagtcgg agggaatatc agaacaagaa atcgatgatt ttgatttact cctaaaactt
     9121 gcctatggtc aaaaagaatt aaccaaaacg gaacgtatca ataaactcaa acaaagcgga
     9181 tatttatata aatatagtga ggaagcgcgt gctgttttgg aaattttact gaacaaatac
     9241 atggataaag gtattggaga actcgaaagc attgaaacat taaaacttcc agaatttcag
     9301 atatatggtg gaaccttcaa aatcatcaat acttattttg gagataaaaa acgatattta
     9361 caagcaatta aagaattgga gcaagagcta tttacagtag cttaatgaaa ggaaagtatg
     9421 tcaattacat catttgtaaa aagaattcaa gatatcactc gaaacgatgc tggtgttaat
     9481 ggtgatgctc aacgtattga gcaaatgtct tggttattat tcttaaaaat ttatgatagc
     9541 cgtgaaatgg tttgggaatt agaagaagac gagtatgagt caattatccc agaggaatta
     9601 aaatggcgaa attgggctca tgctcaaaat ggggaacggg tattgacagg cgatgaatta
     9661 cttgattttg tcaataacaa gttattcaaa gagttgaaag agcttgaaat aacttcaaat
     9721 atgcctattc gaaaaacgat tgttaaatca gcttttgaag atgcgaacaa ctatatgaaa
     9781 aatggcgtct tgttacgcca agtcatcaat gttattgatg aagttgattt caatagccct
     9841 gaagatcgtc attcgtttaa tgatatttac gaaaaaattc ttaaagatat tcaaaatgct
     9901 gggaactcag gagaatttta tacgccacgt gcagcgactg attttattgc cgaagttctt
     9961 gacccaaaac ttggagaatc aatggcagac cttgcttgcg gaacaggagg cttcttgact
    10021 tcgactctga accgtttaag tagtcaacgt aaaactagtg aagataccaa aaaatataat
    10081 acagctgttt ttggtattga aaagaaagca tttcctcatc ttttagcagt tacaaatctg
    10141 tttcttcacg aaattgatga ccctaaaatt gttcatggaa atacttttga gaaaaatgtt
    10201 cgtgaatata cggatgatga aaaatttgac attattatga tgaatccacc ttttggaggg
    10261 tcagaattag aaacaataaa aaataacttt ccagcagaat tacggagttc tgaaacagct
    10321 gatttattta tggctgtcat tatgtatcgt ttgaaagaaa atggtcgtgt tggagttatt
    10381 ttacctgatg gttttctatt tggtgaaggt gtaaaaactc gcttgaaaca aaaactggta
    10441 gatgagttca acttgcatac gattattagg ttgcctcata gtgtctttgc accgtataca
    10501 ggaatccata cgaacattct tttctttgat aaaacaaaga aaacagaaga aacttggttt
    10561 tatcgtttag atatgccaga tggttataaa aatttctcga aaactaagcc gatgaagtca
    10621 gaacacttca atcctgttcg tgactggtgg gaaaatcgtg aagagattct ggaaggtaag
    10681 ttctacaaat ctaaatcatt tacacctagt gaattggctg agttgaatta taatttagac
    10741 cagtgtggct ttccaaaaga ggaagaggaa atcttaaatc cctttgagtt gattcagaat
    10801 tatcaagcgg aaagagcaac tttaaatcat aagattgata atgtattagc tgatattttg
    10861 cagttgttgg aggacaaata atgacaccag aacaacttaa ggcaagtatt ctccaaagag
    10921 cgatggaagg gaaattagtg ccgcaaaatc ccaatgacga acctgcaagt gaattattaa
    10981 agagaattaa agctgaaaaa gaaaaactta tcagtgaagg aaaaatcaaa cgagataaaa
    11041 aggaaactga gatatttcgt ggtgatgatg ggaaacatta tgggaagttt gctgatggaa
    11101 gtactcaaga aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggataa
    11161 aatcaattta ttggaatttt gggcaaaata agccagagaa atcctttagg tatatagata
    11221 cgtctagtat tgatagaaaa aagaacataa tcaactacaa aaatctacaa tatctttcac
    11281 ctgaacaagc gccttcccgt gctagaaaat tagtttcgca gaatagtgtc ttattttcaa
    11341 cagttagacc atatctaaaa aatattgctg tagttagaga acttaaagag tatttgatag
    11401 ctagtacagc atttattgtt ttggatactt tacttaacga aacatatttg aaatattatt
    11461 tattatcaga taattttatc aatcgtgtta ataataaatc tactggaaca agttatcctg
    11521 caatcaatga ttataatttt aatctattat taattgctct ccccccacta tccgaacaac
    11581 aacgaata
//
LOCUS       DAVLHB010000057        11045 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLHB010000057 DAVLHB010000000
VERSION     DAVLHB010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.057"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            15..400
                     /locus_tag="VXE36_001812"
                     /pseudo
     CDS             15..400
                     /locus_tag="VXE36_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            935..1627
                     /locus_tag="VXE36_001813"
     CDS             935..1627
                     /locus_tag="VXE36_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0780061.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1680..4091
                     /locus_tag="VXE36_001814"
     CDS             1680..4091
                     /locus_tag="VXE36_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0780062.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     RGQEYIEAARASLNDREDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSAMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4341..5042
                     /locus_tag="VXE36_001815"
     CDS             4341..5042
                     /locus_tag="VXE36_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780063.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNSDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5044..7752
                     /locus_tag="VXE36_001816"
     CDS             5044..7752
                     /locus_tag="VXE36_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0780064.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYTVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7848..8339)
                     /gene="tpx"
                     /locus_tag="VXE36_001817"
     CDS             complement(7848..8339)
                     /gene="tpx"
                     /locus_tag="VXE36_001817"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0780065.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTNLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8462..9391)
                     /gene="psaA"
                     /locus_tag="VXE36_001818"
     CDS             complement(8462..9391)
                     /gene="psaA"
                     /locus_tag="VXE36_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0780066.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9423..10271)
                     /locus_tag="VXE36_001819"
     CDS             complement(9423..10271)
                     /locus_tag="VXE36_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0780067.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10268..10990)
                     /locus_tag="VXE36_001820"
     CDS             complement(10268..10990)
                     /locus_tag="VXE36_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0780068.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3224 a         2064 c         2527 g         3230 t
ORIGIN      
        1 aaggagattt tattatgaaa ttaaaaacac ttgctttaat tagtggtatc gtcggtcttg
       61 tgggaggaat tttacttctt attggtcctt ttgtcttgtt gggaacagcg gtaaacacag
      121 ctgctacaac tcttaatgga ggagctactg caggggcttt ttcaggtgtt gccttactct
      181 tgaatgcctt gaagattgca aatcttgttc ttggtatcat tgctattgtt tactataaag
      241 gagataagcg tgtaggtgca gctccgtctg tactaatgat tgtttctggt ggagttagtc
      301 tcattctatt ccgttcttag gatgggttgg ggggattctt gctattatcg gaggatctct
      361 attcctttca acattgaaga aattcaaatc agaagaataa aaggtatttt agcatgaaaa
      421 gaacaaaaaa gtttatcggt ataggagtag ctctattatc tctttctctt ctagttgcat
      481 gtggaacata aagttcaaag aatacttcaa caagtaatga tgagaagaca gtagcaacat
      541 ccaatagttc aaaagaaaca atcactttcg atataccggt tgtaacagac gatgcgattg
      601 aatcaatacg cacttatgca gattatatag atctttataa aaatattttt gatgattatt
      661 ttactaaagc tgaggaaggt ttcaaaggca cagctatgga aaataatgac tcgtttacta
      721 aactaaaaga gtcaactcaa aaattattcg atgcgcagaa aaaaaggtta aataatgaag
      781 atagaataga aacagccaaa aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct
      841 ttttggtttt gactagcttt tttgtgaaaa attgtgtaaa atagaataga taaacgaggg
      901 gaaacctcgg aaaatttaaa ggagaatcca tctaatggta aaattggttt ttgctcgcca
      961 cggtgagtct gaatggaaca aagctaacct tttcactggt tgggctgatg ttgatttgtc
     1021 tgaaaaaggt acacaacaag cgattgacgc tggtaaattg atcaaagaag ctggtatcga
     1081 atttgaccaa gcttacactt cagtattgaa acgtgctatc aaaacaacta acttggctct
     1141 tgaagcttct gaccaattat gggttccagt tgaaaaatca tggcgcttga acgaacgtca
     1201 ctacggtggt ttgactggta aaaacaaagc tgaagctgct gaacaatttg gtgatgagca
     1261 agttcacatc tggcgtcgtt catacgatgt attgcctcca aatatggacc gtgatgatga
     1321 gcactcagct cacacagacc gtcgttacgc ttcacttgac gactcagtta tcccagatgc
     1381 tgaaaacttg aaagtgactt tggaacgtgc tcttccattc tgggaagata aaatcgctcc
     1441 agctcttaaa gatggtaaaa acgtattcgt aggagctcac ggtaactcaa tccgtgccct
     1501 tgtaaaacac atcaaaggtt tgtcagatga cgagatcatg gacgtggaaa tccctaactt
     1561 cccaccattg gtattcgaat tcgacgaaaa attgaacgtc gtttctgaat actaccttgg
     1621 aaaataaaaa attgtaagtc tagaattgat ttctaggctt tttatgttag tatggaagta
     1681 tgataaggaa taaaaaacaa gattatgtac tggcctacaa gcaaccagct tcaaccactt
     1741 acatgggttg ggaagaagaa gctttaccga taggcaatgg ttctttagga gcaaaagtat
     1801 ttggccttat aggggctgaa cggattcaat ttaatgaaaa aagtctctgg tctggaggtc
     1861 cacttcctga tagttcagat tatcagggtg gaaatcttca ggatcagtat gtttttttag
     1921 ctgagattcg gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc
     1981 agcacctaat tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc
     2041 acattgagtt cagccagcaa ggtacgactt tgtctcaggt gacggactat cagagacagc
     2101 tgaatattag taaggcactt gcgacgactt cttatgtcta taagggaacg cgatttgaac
     2161 gtgaagcttt tgcgagtttt ccagatgatc tcttggttca atgttttact aaggaagggt
     2221 tggaaactct agattttact atagaactat ccttgacctg tgatttggct tctaatggaa
     2281 agtatgagca ggaaaaatct gattacaagg agtgtaagtt ggatattact gattctcata
     2341 tcttgatgaa gggaagagtt aaggataatg atctgcggtt tgctagttat ctagcttggg
     2401 aaacggatgg agatattaga gtttggtcag atagggttca gatatcagga gccagttatg
     2461 ccaatctctt cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca
     2521 agaaactaga tttagagcaa caggtgatag acttggtgga cacagctaaa gaaaagggct
     2581 atacccaatt gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat
     2641 tggatttgga agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc
     2701 cacaagaagg gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta
     2761 gttcgtccag agactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg
     2821 tcgacaatcc tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt
     2881 ggccagccta tgttaccaat ctcctagagg cggtctttcc ggtcatcaac tatgtagatg
     2941 atttgcgtgt ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc tctcaaaaag
     3001 gtgaggaaaa tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg
     3061 gttgggatta ctattggggt tggtcaccag ctgccaatgc gtggatgatg caaaccgttt
     3121 atgaagccta ttcattttat agggaccaag actatctcag agagaaaatt tatcccatgt
     3181 tgagggaaac ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt
     3241 gggtgtcttc tccgtcttat tccccagaac atgggccgat ttcgattggc aatacttatg
     3301 accaatctct gatttggcag ttatttcatg attttattca ggctgctcag gaattgggac
     3361 tggatgagga cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa
     3421 tcactcaatc tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg
     3481 agaaagtgga ggcccagcat cggcacgctt cccatctagt gggactctat cctggcaatc
     3541 tctttagcta caggggacaa gagtatattg aagcggcacg tgctagcctc aatgatcgtg
     3601 aagatggcgg cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag
     3661 atggcaatcg agcccataaa ttattggcag agcagttaaa aacatccacc ttgccaaatc
     3721 tttggtgtag ccatcctcct tttcagatag atggtaattt tggtgctact agtgccatgg
     3781 cagaaatgtt actccagtct catgcagctt atctggtacc tctagctgcc ctacctgatg
     3841 cttggtcaac aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga
     3901 gctgggaaga taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc
     3961 gagtttctta tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag
     4021 cgaaatgcat ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat
     4081 tttattttta agaagatgtt ataaggcagt aatttgaaac tgccttttaa taaggattta
     4141 agaatataag cagttttcaa ctagttgaaa aagcgttata atgataatag gaagtaatac
     4201 tcaatgaaaa tcaaagagca caaactagga agctagccgc aggttgctca aaacagtgtt
     4261 ttgaggttgc agatggaagc tgacgtggtt tgaagagaga gtttcgagga gtataatttg
     4321 tttgatagag ggtgggtctg atggcttata ttgagatgaa acactgttac aagcgttatc
     4381 aggttgggga cacggagatt gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg
     4441 agctggttat tatccttggt gcttcaggtg caggcaagtc aacagttctt aaccttcttg
     4501 ggggaatgga taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt
     4561 atagttccca ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt
     4621 ataatctagt ttctaatctg acagctaagg aaaatgtgga actggcttct gaaattgtga
     4681 cagatgcctt gaattctgat caggtcttga cagatgtagg tctggctcat cgtctaaata
     4741 actttccagc ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag
     4801 ccaaaaatcc taaaattctt ctttgtgatg aacctactgg agccttggat tatcagacgg
     4861 gcaagcaggt tttgaaaatt ctccaagata tgtctcgtca aaagggagcg acggtgatca
     4921 tcgtgactca taatggagct ttggcgccca ttgctgatcg cgtgattcat atgcacgatg
     4981 ccagtgtcaa ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact
     5041 agtatgatca agcgaaaaac ttattggaag gacttaattc agtccttcac aggctccaag
     5101 gggcgttttt tatccatctt gatcctgatg atgttgggat ctctagcctt agtaggcctc
     5161 aaagtaacca gtcccaacat ggaggcgaca gctaatgctt atttaacaac tgctcaaacc
     5221 ttggatttgg cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa
     5281 cagacggagg gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg
     5341 caggatgcca ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag
     5401 ggacgacttc ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatac
     5461 agcgtgggac aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac
     5521 catacttata ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg
     5581 ggctacgcag gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcaa
     5641 tttgatcaga aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat
     5701 gccttttcat cagcttatga agaaaaatct aagcaacatc aggaagagct tgaacaaatt
     5761 ttatcagata atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta
     5821 gacaaggggc aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt
     5881 ttagcagctg ctcaagctcg tatacaggct caagaaagtc aactagcctt gtttcctcaa
     5941 gttcagagag agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa
     6001 gaggacaaac taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa
     6061 catcagcaag tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc
     6121 atgccaggtg gtcagggcta tcttatgtat agcaatgctt catccagtat tcgagcagtg
     6181 ggcaatatct ttcctgtggt actttatacc gtagcagcca tggtgacctt tacgaccatg
     6241 actcgctttg tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttaccgt
     6301 agtaaggata ttatcgccaa gtttctcctt tatggactag tagctgggac tgtcggaacg
     6361 gctctaggta gtatacttgg tcattatttg ctagccagtg taatttcaag tgtcattaca
     6421 aaaggcatgg tggtgggaga aacccagatt cagttctatt ggacctatag cttactagct
     6481 cttgtcttga gctggttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt
     6541 catgacgaag cagcccagct tctacttcct aaacctcctg tcaaaggagc taaaatctta
     6601 ttggagcgta tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc
     6661 aacatctttc gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta
     6721 gctctgctct ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag
     6781 tttcaacaaa tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag
     6841 gacaaggtag agctagcaga agtgttgaaa gggcaggaga tactagccta ccagaaaatc
     6901 tattctaaaa cgctagacaa ggatttcaaa ggcaaggctg gtcttcaaaa cattactctt
     6961 atgatgatag agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag
     7021 ctgacattaa aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag
     7081 gttgggcaga ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac
     7141 tacgttggtc actttattta tatgagtcag gctagctatg agcaacttta cggacagcta
     7201 ccccaagcca acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt
     7261 caggcgggct tgcttatgaa tcaatctgcg gtgtccagtg ttgtccaaaa tgcttcagcc
     7321 attcgactct tcgactctat cgctagctca ctcaatcaga ccatgaccat cttggtcatc
     7381 gtatcggttc tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag
     7441 agaatccgtg aactctccac tatcaaggtt ctcggttttc ataataatga agtcaccctc
     7501 tacatttacc gtgagacgat tgtgctgtcc cttgtgggaa tcgtacttgg tctggtagct
     7561 ggtttctatt tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat
     7621 ccgcaggtag gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc
     7681 ttgcttggtt tcttcgtcaa ttattatctg agaaaggttg acatgttaga agccctgaaa
     7741 tctgtagagt aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa
     7801 tcctccgttt caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta
     7861 gcagctgcaa ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg
     7921 tagcgaatcg tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg
     7981 ttgatcaaga gggcataatc gcgtccgaaa gaatggtcaa agtagtctga aagcataatg
     8041 gcattgtcaa ggccttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa
     8101 acagtcaata cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga
     8161 gttgagcaga tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca
     8221 aaatcagcca gagatttttt agaaagattt gttgtagtaa gagaaaaatc aagcgccttg
     8281 tcgccgactt gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata
     8341 ggatactcca atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt
     8401 gaccggaaat gtgtgcatag aaaaaacgcc agctcacatg agaatgacgt ttttcagagg
     8461 cttattttgc caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc
     8521 tgtcgccttc tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga
     8581 tgtttgtgtc ttgagaaaca gttttcattg gacggtcatc cacacttgat tctacaaaga
     8641 gtgatggaac ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc
     8701 cttcttcttc agtattgatt tcccagatgt aggcacttgg gacaccatag gctttagaga
     8761 agtatttgaa tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa
     8821 atttatcctt actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt
     8881 tttcatagaa ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag
     8941 caaaaataat accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat
     9001 tttgaccttc aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt
     9061 cagttttctt ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt
     9121 tgataccgtt atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg
     9181 gttcgtattc gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac
     9241 cagcaatatt tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt
     9301 gaccagaagt tgtatctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa
     9361 agagaacgag taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc
     9421 ccttatttta acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag
     9481 aagctaatga gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta
     9541 aaactatagc caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg
     9601 aaaatcatgc ttttcagact attagcatac agataagcag ttgcagctgg ggtaatcagc
     9661 atggctacaa tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg
     9721 agtaccatga gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt
     9781 tcatcaaagg aagttatcaa gagttgcttg aagaaaatcc agattaacaa gaggatggct
     9841 gcccccacac ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa
     9901 aggatatgga aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct
     9961 aagaaagaag aaaaggtaat gccgatggcg gtatcgcttt tgataatcga gtttcctttg
    10021 atgtaggtaa tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca
    10081 aggcccaaga tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc
    10141 atgagtgaca tcccgcgtag aataatgaaa catcccacgg ctccagctac aatcccgacg
    10201 acaatagctg ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat
    10261 tctgcaatca taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat
    10321 tggtttcggt aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta
    10381 agacttgatc gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct
    10441 tcccagcttt tttcaaatct ctcagcgtat tcatgatgat ttcctcactg acagagtcaa
    10501 tcccagcaaa gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa
    10561 tcaagacccg ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag
    10621 ctaggccgac gatttcaagg gcctcttgca ctttcttcca atgtttagcc tttaaacttc
    10681 gaaagagagg aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa
    10741 agttgtagtc gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa
    10801 cttccttgtc atcgagaaat gcctgacctt gatgtgggat aattcccaac atacctttta
    10861 atagtgttga tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga
    10921 gcactagtga aatatcctta agtgccaacg tttctttgta ggagacactg aggttttcga
    10981 tacgtatcat aaacttatat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt
    11041 caagt
//
LOCUS       DAVLHB010000058        10767 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLHB010000058 DAVLHB010000000
VERSION     DAVLHB010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.058"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..1225)
                     /locus_tag="VXE36_001821"
     CDS             complement(<1..1225)
                     /locus_tag="VXE36_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEV0780069.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTVVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKHYEEAKKKAEDAQKKYDEDQKKTEDKAEAVKKADEELQKANLEV
                     QKAYVEYQKAQREHNESRGRKKADAKKKLVAALSHIEEVESKQIEAKANFNKEQAKVI
                     PKETELATTKQKAEEAKKEAEVAKKKSEEAAKEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKEIADAEKTVADLEKEVAKLEKDVEGFKESDGEYAEFYLEAAEKDLATKKAEL
                     AEAKIKATTKKAELEKAEAELENLLSTLDPEGKTQDELDKEAAEDANIEALQNKVADL
                     ENKVAELDKEVTRLQSDLKDAEENNVEDYVKEGLEKALTDKKVELNNTQKALDTAQKA
                     LDTALNELGPDGDEEE"
     gene            complement(1511..2014)
                     /locus_tag="VXE36_001822"
     CDS             complement(1511..2014)
                     /locus_tag="VXE36_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780070.1"
                     /translation="MKLLDCILDYQERFNRKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDFASHTISVIQTGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKLTSCC
                     IVAKDLSKNTMKLDVIFFEDKNKISAVLGLRRDKSGVFKPVTLYFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            complement(3150..3878)
                     /locus_tag="VXE36_001823"
     CDS             complement(3150..3878)
                     /locus_tag="VXE36_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780071.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            complement(3875..4207)
                     /locus_tag="VXE36_001824"
     CDS             complement(3875..4207)
                     /locus_tag="VXE36_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0780072.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(4263..5165)
                     /locus_tag="VXE36_001825"
     CDS             complement(4263..5165)
                     /locus_tag="VXE36_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780073.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLMYEMSISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(5373..5747)
                     /locus_tag="VXE36_001826"
     CDS             complement(5373..5747)
                     /locus_tag="VXE36_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV0780074.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(6123..7100)
                     /locus_tag="VXE36_001827"
     CDS             complement(6123..7100)
                     /locus_tag="VXE36_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780075.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQRLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISFIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            complement(7414..8472)
                     /locus_tag="VXE36_001828"
     CDS             complement(7414..8472)
                     /locus_tag="VXE36_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780076.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIIKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(9354..9566)
                     /locus_tag="VXE36_001829"
     CDS             complement(9354..9566)
                     /locus_tag="VXE36_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780077.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(9574..9945)
                     /locus_tag="VXE36_001830"
     CDS             complement(9574..9945)
                     /locus_tag="VXE36_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV0780078.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
BASE COUNT         3698 a         1978 c         1364 g         3727 t
ORIGIN      
        1 tttcttcttc atcaccgtca ggacctaatt cattaagagc agtatctaat gctttttgag
       61 cagtgtctaa tgctttttga gtattattta attcaacttt tttatcagta agagctttct
      121 ctaagccttc tttaacgtag tcttctacat tgttttcttc agcatctttt aaatcgcttt
      181 gaagtctagt aacttcttta tctaattcag caaccttgtt ttctagatca gcaactttgt
      241 tttgaagagc ttcaatatta gcatcttctg cagcttcttt atctaattca tcttgagttt
      301 taccttcagg gtctaatgta gataataggt tttcaagttc agcttctgct ttttctaatt
      361 cagctttttt agtagtagct ttaattttag cttctgctaa ttcagctttt ttagtagcta
      421 ggtctttttc agcagcttca aggtagaatt cggcatattc accatctgat tctttgaaac
      481 cttctacatc tttttcaagt ttagcaactt ctttttctaa atctgctacc gttttttcag
      541 catcagctat ttctttttct aaatcagcga ctttgttttg aagtacgtca attttctttt
      601 cgttttcagc atcttgttca agtattttat ttttctctac ttctacctct ttagctgcct
      661 cttcagattt tttcttagct acttctgctt cttttttagc ttcttccgct ttttgtttag
      721 tagttgctaa ctcagtttct ttgggaatta cttttgcttg ttccttatta aaattcgctt
      781 tcgcctctat ttgttttgac tctacttctt caatatgaga taatgcagca actaatttct
      841 ttttagcatc agcttttttt ctgcctcgac tttcattatg ttctctttgt gctttttgat
      901 attctacata agctttttga acttctaaat ttgctttttg aagttcttca tcagctttct
      961 taactgcctc tgccttgtct tcagttttct tctgatcctc atcatatttt ttctgagcgt
     1021 cttctgcttt ctttttagct tcttcgtaat gtttcttagc agcttcagat tttttcactg
     1081 ctgcatcata gtctttctca gctttagact gactagctac gggagcttct tctgctctta
     1141 caacagtagg ctgagacgta acaaaaccag cccctaagat agcgacgctg gctagacttg
     1201 ttaaaatcat ttttttctta ttcatctaaa tttacctctt ttctgatagc catttttaga
     1261 ctatacttat attaagtata ctccccccgt aaatatttgt caaatgtttt atattacatt
     1321 tttattacaa atttctatat cataagcttc tactccaaaa agataaagac actacttttg
     1381 cccttttcga ttctcttttt aaacatagca tcatcttcct tcattcctat aaaaacactt
     1441 ccgatgagag agcttgtttt ttaatttcgt taaacaacaa aaaacgcaag cttaagcctg
     1501 cggacaatct ttatagccat ttcatttctt tcacatctgt tttacgaact ttagcatatt
     1561 tcttagcgct tgtaaaatat agagtaactg gtttaaatac tccgcttttg tctcttcgta
     1621 aacctaaaac tgcggatatt ttatttttat cctcaaaaaa tatgacgtcc aatttcatag
     1681 tatttttaga taaatcctta gctacgatgc aacaacttgt tagcttagaa tagaagatat
     1741 cgccgataaa ctcatataaa gatatccttt cgattacatc attgtacaat aggatatttc
     1801 taaaatcttc taaaataaaa acaccagttt gaataacaga tatcgtatga ctagcaaaat
     1861 ctcgtgtgat tttgtgtaag ccaaataaat gatgtaaatc agtcaggcaa aaattcactt
     1921 tgaaagtctc taaatactta taattcgttg atacttgaca tgtttttcta ttgaatcttt
     1981 cttgataatc caaaatacaa tcaagtaatt tcaacgacaa actccatatt ttctcaaaat
     2041 aaaaagcacg gggcagttct cactactgcc caaagtgttt gattagagtc ggcttctcta
     2101 actccctatg ttgtgcttat taggcttatc gcaagggaac agtttttagc tctgccaagc
     2161 cacatagtgt gcttactact atgtgtccat gtcaccatga attgccgaac ggtttaacga
     2221 gaaagtatag tagattgaaa caagatgtga acaaatcgat taggaaagtc aaattaattt
     2281 ctagaaatat tttaacggtc ataacggact attccagatt caatctacta tattattttt
     2341 aggtttatcc caactcaatt atgacatctt tttttcaaaa gtcaatatat ctcactcttt
     2401 tcaacgacaa gaaagaggct gataatcgac caatctctgt ttttagatac agttcaagtc
     2461 caaactattc tttatagaaa aaagtcctat aaattcgagc aatagttaac atacttacaa
     2521 atataattcc caaaatagat aacactattt tcacaaaact cagttccgaa cctatgacat
     2581 atatatgaaa aagaggggct agtcctacac atatatacaa taagtagcca acaagtttta
     2641 tctcaccaat tcctgcaaaa aaatgtttca tgtaacgatt ctccatttac tccattaaat
     2701 cagttttatt ttagactatc ataaaacaat cacctcttca ataaaaacca ttggcgaaat
     2761 actattctga agcattgata gctcagattt ctcagaataa agctgtccta actatcgagc
     2821 agctcaaata catatatatg agcaattcta agcttagaat tgttataaaa taaatgtttt
     2881 cgggctattc taagtctttg actgcttaaa attttacgtt ctgaaggatt ctaaagctag
     2941 aatagctcaa aatcacgaga actaaggtat tcgaaacttc agagtaatac aatccccata
     3001 ggaattctcc attcttatta aggatgatta aaatgtaatc ctaacaagtg atcctcgact
     3061 gtgtttgtag cacttagtta cctagataag actatttccc tttatcatat ctgattttaa
     3121 gccgttctaa gatttaacct atgtttctat tacttgctat ttttaaataa ttcgtattcc
     3181 ttttctttga taaatggaac tgaaaaatta gaaaaaagaa gtaaaaccga aaacaaatag
     3241 cctgcttttt gaatcactaa aagatatcct aaaaataagt aagctataac atccaatgcg
     3301 aaaagaaaaa atatcctcct cttcattaaa gtacttgtgt caaataatct gatgaataaa
     3361 aattttatcg tagtatctac acaaattttt atcaaaaaga taagagccaa tacacgatta
     3421 tcaactgtac cataaagaat agatggaaat atagttaata taaaactaga aatctctaaa
     3481 tattttatcc aaggagattg agacaccttg cttctaaact gactaatttt cttatattcg
     3541 ttagtcaatt tagtagcaaa atctttccca attaaatgaa aaattatcaa ctctgtaata
     3601 aaaacactta ttaatacggt ataagtcaaa aaactttctg ggaaaaactt attgattaaa
     3661 atggggaaac tcattaacag aatcgaattt atggctagac agatagatac tattttattt
     3721 ttcacagaat atagaggtag tgatactatt gagtagataa aagctaaaaa aataagcaaa
     3781 aaatactccg tgtcatttat aatcgccctg aatgataaaa atatatacat ccaacatacg
     3841 ataatatgta tttttcgaat cttatctaca ttattcatct tactgtcgca gatataaatc
     3901 catcccaagg ataagggttc ccgctaatat cacaacctct attaagagca ccatatccaa
     3961 tacagtaagc tatttttcct gctgctgcac caataagcca gcctccaaga cctccaacct
     4021 taatatagtt tattagtttt ttggttaaaa ctgcagctcc agctaatgct ataaaagttc
     4081 ctgaactcat agctaaagct acgcaaattc cttgacaagc acgcttgctt aaataagctc
     4141 ccccatcaag atacatcatt tcttcttcat caatcacaac ataattattt ggtaatacaa
     4201 gttccatttg ttttctcctc cttagttgaa attgtttcat ttgttttaca aataggacga
     4261 acttaaacta tctttttatt actcagtaat aatttccgag atttcatttt atgatactct
     4321 ctattcatac agaaatcaaa attttgcctt aaccaacttg tataatagaa aaaatctaat
     4381 tgatttattc tgatgagctg tatcctaatt ttatcaacct tttcttgcca gttgttattg
     4441 ttactaatag acatttcata catcagtaac tcgacaagac ctgtacacag aagggtgtta
     4501 tgagaatctt cgattttttt caaaatatcc tcaaaaagtt cactatccgt taaaaaggtg
     4561 gattggttca tcgcatcata cagctgaaga gacattaagt cagaataact tagctctgat
     4621 ttttgtatct tatcctttaa cgttttcgtc aaatcgcttt caaacgaatc ttctttttcc
     4681 catttatttt gattaaaaag aaattccgtc ttattaaaaa cgagatgatt gatatccatt
     4741 atagtccaga aaaatattgt agtaagcatg atgattgcaa aaggaatttt taaaataaat
     4801 actaggataa tagcaatttc aagaataaaa ctccatataa tcctagatct taaatcatca
     4861 ggcgacaaac ttttacgatg gaatgaaaaa tagggcgaga atctcacatt cacttttttc
     4921 cttcttataa aaataaaggg aaaaatctta ataagacctt ctttcttgta taaatctttc
     4981 aatgcgtata gtatgtctaa aactattttt gataaaatca aactacagaa agcaagactc
     5041 atactaatca caaaatcaag gggagattct agattcaata gtaagttatt cactaggaca
     5101 tgcaactcta gccacaagac aaaaagaggg agcattagta agaaaacaat tagtttacgt
     5161 atcataattt tacagtgtcc ttatcatttt cttaattttg gataaatcat cattgctatg
     5221 attaaaatca aaaaaacgac attcatccaa ataatcaact tttttatttc ttcgctaaca
     5281 aaatcatagg ctaaaaaagt tatggatgat ataaatagac atacaaaaaa aataataaca
     5341 aaaatttttt ccattttaat acccatatct agttaccaca aggcgtttaa atttgggtct
     5401 ctcctattta catcattgtt ggcccagatt gttgtaatag catcgccaat tgacatccaa
     5461 gctgcaaatc cattaatagc agacagtgca aatcctgcca ctctatttgc aactcgtacc
     5521 ccaacatatc ttgcagctgc tccagcaatt gcgcttgtaa ctcgccgcaa accataatta
     5581 cgaatataat ttctaactag actgattgct cctccaccta aaacaccatt aaaagctata
     5641 ttaatggctg ttgcaacagg ccatctcgga atagaaaatc ccccatcaag atacatcatc
     5701 tcttcttgct caagaacaac ataattattt ggtaatacga gttccattta ttttctcctt
     5761 ttttattaag tatggttagg atggtttcct aacaagtaat cgtcgactgt gtttttatca
     5821 cttagctacc tagataagat atcctttctc taccttattt gtttttatag gttacctaag
     5881 gtttaaaacc aattattgtt tgaaacttaa cagttctaaa ccactagcaa taaatgattg
     5941 cgaactcact aatactattt caaaatttat ttttttgact tagtaacgca attccaatta
     6001 gcaatacacc tattataaat aaaagtattt cccaaaattt attatccgtg ttaatgagag
     6061 gtataagata catactgact aatatgcaac ttgcccctat aatagcaaat gttattctag
     6121 ttttatctcc taattgaaac atgtttgatc cctatataca cttcaagcaa aagttggatt
     6181 tctgaaatag ctaaagataa agataatggt tgcgagctat ttaaactatc atcaatattc
     6241 tgctcgatta aaacaaagtc tggtcttacc tctaaaattt tatttaacat tgattcatat
     6301 ttattttttt cattataatg ccgtaaatat agatttaatt ttataacatc caacatacca
     6361 taaagtgata ttggatgatt tattttttta aatcgcttaa cttctaataa atcaatttgt
     6421 tcacgcacgc tctctgaaag atatggcttg ataaaactga tataagataa agccacgcat
     6481 ggcaactcag attttgattg caatttccaa atttcatgat aatcctgaag attaaactca
     6541 caatccctct tagattccag tattgttagt acctttgatt ttaacagaaa taattgttga
     6601 ttctcaattc tataaagttt ttgtactaat gctatgataa tagaaaatgg aataagaggc
     6661 aaaagcaacg atttgtcata cacaaaagta aagaaaaaat agtatgaaat tagtgttgta
     6721 aagtacaaga agtagtaaaa tttaaacaga ttcttagttg tttgactctc cttataaaac
     6781 actgctattc ctggactaaa tcccattagt tggtgaaaga gaattcgata gtatttccta
     6841 gctcctataa tgatcacaaa tataaaataa aaataaattg gtcttaattt acaaaagatt
     6901 gaggaaacta gtaatagcaa agtatgtaag cgttgagaca aaatatagaa taacggtatc
     6961 gccaatacaa aggttaagat ggcatgagag ggggttccta agatgtccaa ttttataaat
     7021 actgggctga cacaaaatat cgtgcttata agcagtaaaa ttattaaaat tgtgtcaaaa
     7081 aaataacgct tatttttcat tagtctactt tccattgtta aataatacta ctgctaacac
     7141 caagccaact tagcacattg catcacctaa tcctgcgcta cttgtccata atcctttaat
     7201 gtttctacta aaattattcc aatctccccc atcaagatag cttatttatc ctagacaacg
     7261 cctactgcaa cagtataaat aagattcatc agccatcttt tctggcaatc atatgggtag
     7321 cctaatgata tttctagtta ctcaaaaata tctagctata ctagagttat ttctaatccc
     7381 taggacactt gttaatccaa atgtaacaaa ttttcacccc ttaataggac tctttctgga
     7441 aaaaatataa ggtctatctt tataaaaaaa tctatcatat tgggatggca cgcatctgga
     7501 atttaaacaa gctataaatt catttataac tactatttgt ttagaagcaa cagcatcttg
     7561 tataccgccc tcgaaagaac catcttgtaa ttccgaaata tttttgttta aatattgttt
     7621 tgacaaatct cttaatgctt cattatcgta aatgattccc aaaaatccaa ccttatatag
     7681 taaataattt aaacttacaa agtaattgaa tcccatagta tatttttctt tataaagcaa
     7741 aggtaaaact ttataaaaaa tatctaagtc aacctcactc tgattctgaa gcaagtagga
     7801 gtcaagcaaa ttttcaaaaa tagctaacaa tatgattggt gtaaggtttt tgtattcaca
     7861 tgtcaagtat tctgagtatc gtgcagatga tatttctttt atataacttt ttgaaagcaa
     7921 gattttttca aattcatcat ctattattaa tcttctattt ccaatccaag cggtattacc
     7981 acccaaataa gattgtgcaa atagcaatat gtaagaaaat atgaacgtaa atactgaaag
     8041 aggtagaatt ctatgcgtaa aaaaatagac gataatggta gccaggagta aagatatctc
     8101 tcgtgacaat cgaattcttt tcagcatctt ttttaacagt ccgtaaggtt gtccttggca
     8161 atattcttga actaaattaa tcggaatgac atctctcacc atttctggaa agtagagtaa
     8221 gtttataggt tgaaatctcc agctcccatc ataagtaaat ggatatagaa ccaaatactt
     8281 aaaagatttt tttattataa acttaattat cacaatatga atgactgttg caatgaagta
     8341 tattaaatat aaaagtaaaa ccgccatcaa tatacttaca aaaatcccct tggactcaat
     8401 caatggaaaa taaaatattg caactagaag cgaataaagt cccgctaata aatatttctg
     8461 atcatctttc attcaaaaca ccatattatt tactaagaat acatcaatac aatagagcaa
     8521 ctctgtaagt caatatttga taaagcaaag ctttaacccc ttccccagac gttagctttt
     8581 cttcaaccca ctacagttga caaggagccc aaattattga taaaaacttt agtcatcatc
     8641 gtctctataa aaatattttc tatacactct tgataatacc aaaattaata ccaatatcat
     8701 accaagagct ataataatag aatttattag atttatttta gtatatccaa tcactagtcc
     8761 aataattgga ctagcagaca tgcttagata taataaaaat aacaaaaaat gaatttcacc
     8821 aattcctgca aaaaaatgtt tcatagctat aattttacgc ccataaatac ccatcaaatt
     8881 taccgtctac gatatctaaa ccatatgcaa tggctcctcc taatgagaag acttcagcaa
     8941 cagtagccgc aatattaaga gcattagtaa tagttgccat actaactcca ccaatatatc
     9001 ttgttatagc acttagttac ctagataaga tatcctttag cttgcttcca aaatttaagt
     9061 ctgcacctat aatatgagtt catattagta ctgctaaatc ctatctatag taatgtcaaa
     9121 cacctaaata aagtcatctc tccgattcat tcaagaaatg aagaaaggca aaaaatcttt
     9181 aaaataagaa aagtgcatat tatcaggtgt tcaaaaatat tgatgatata cgttatatag
     9241 atagaaagat ttactcaatc tcactttcaa attgagtttt ttcccaacct cgtttttaat
     9301 ttatatcttc aataaaatct aatgacctag ttgatatgtc atatggaata atattattta
     9361 atctgtaatt tttttaaaaa acttaatagt aaatttgctc cactgattgc tatcaatatt
     9421 tcaattggta aaaaatagta attccaaata aaatgagaaa tcagcaatga tagaaaaata
     9481 acaatatcaa ttttcctgtt gttgacatac tctgtaattt tatgatacag gaatgcaaca
     9541 ataactgaaa ttaaaacaat caacataaga ttattatcct attctcaatt gattatcacg
     9601 tcgcccatcc cagccatcaa taatattggt aaaaatccaa tcagctccag caccaattcc
     9661 agcagatgca atacttctaa taacagtatt tgcaaaagca tttccaatat gaattcctaa
     9721 tactcctaaa cctttaacaa tcccagctac cagtgcggag cgtaatccat aagatgcaag
     9781 aactagttga aggcctccac ctcctgctgc tgctaatgct gcatatgctg caccagtaat
     9841 ggctcctgta attgcccacc tgggtatata tatagccccc ccatcaaggt acatcatctc
     9901 ttcttcatca atcacaacat aattatttgg taatacaagt tccatttatt ttctcctttt
     9961 ttattaagca tgcttaggat ggtttcctaa caagtgatcg caggctttgt ttagttacct
    10021 aaattagact tccttccttt atcttatttt aaatatttaa aaccagttac tgcttgaagc
    10081 ttaacagttt acttaattca aataacagct aatcactgat tccctgattt tatcaaatat
    10141 actaataaca acaattgtga tacgatcatc attataagaa caacatttaa cgaatcaaag
    10201 tttttccgag ataataataa agcaacagca agcagtatta ttactaaaga ttgaataact
    10261 actattactc ttaacatttt atcctctact aacaactcaa gctcccttac attatatcga
    10321 ccagccccat ggaaagatta tagctagact aatcaatgat ataatacata ctagaataca
    10381 aaatattttt ttattcatac tttttctcct atctttattt tctacctaca tagtacctct
    10441 tattaagctc atttcaaaat tacgttaact tttttcacga aaaggagaaa attatgcgtt
    10501 acgattatgg atagcgcttt caaattttta aactcctatc ccatcctttt atctatatta
    10561 tgagcgaaaa tataataact gtcaagtaac taaagtgaat tttataaaaa aattacaagc
    10621 caaatttgta aagtttacac taagccgcta gggcaatcgt ctatcagaat gtccgtttat
    10681 ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc tataaaaact atcaacattt
    10741 atatgacttg cgaatagcaa tcctgct
//
LOCUS       DAVLHB010000059        10721 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLHB010000059 DAVLHB010000000
VERSION     DAVLHB010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.059"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            1..367
                     /locus_tag="VXE36_001831"
                     /pseudo
     CDS             1..367
                     /locus_tag="VXE36_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            491..697
                     /locus_tag="VXE36_001832"
                     /pseudo
     CDS             491..697
                     /locus_tag="VXE36_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            597..1043
                     /locus_tag="VXE36_001833"
     CDS             597..1043
                     /locus_tag="VXE36_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0780079.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1181..2485)
                     /gene="eno"
                     /locus_tag="VXE36_001834"
     CDS             complement(1181..2485)
                     /gene="eno"
                     /locus_tag="VXE36_001834"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0780080.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2649..3095
                     /locus_tag="VXE36_001835"
     CDS             2649..3095
                     /locus_tag="VXE36_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0780081.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3092..4207)
                     /locus_tag="VXE36_001836"
     CDS             complement(3092..4207)
                     /locus_tag="VXE36_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0780082.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVEYLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTYGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLDLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4216..4864)
                     /gene="serB"
                     /locus_tag="VXE36_001837"
                     /pseudo
     CDS             complement(4216..4864)
                     /gene="serB"
                     /locus_tag="VXE36_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            complement(4923..6356)
                     /gene="glgA"
                     /locus_tag="VXE36_001838"
     CDS             complement(4923..6356)
                     /gene="glgA"
                     /locus_tag="VXE36_001838"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0780083.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGFPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6353..7492)
                     /gene="glgD"
                     /locus_tag="VXE36_001839"
     CDS             complement(6353..7492)
                     /gene="glgD"
                     /locus_tag="VXE36_001839"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0780084.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKSAKVTEDIHS"
     gene            complement(7482..8624)
                     /locus_tag="VXE36_001840"
     CDS             complement(7482..8624)
                     /locus_tag="VXE36_001840"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0780085.1"
                     /translation="MKNEMLALILAGGQGTRLAKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGIDSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLELGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8614..10542)
                     /gene="glgB"
                     /locus_tag="VXE36_001841"
     CDS             complement(8614..10542)
                     /gene="glgB"
                     /locus_tag="VXE36_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0780086.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYRDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNKTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3277 a         2348 c         1892 g         3204 t
ORIGIN      
        1 atgcgctcaa agctatgggc tacactcgaa aaaaaagaac cacacctact atgaacaaga
       61 gccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc tagcacctgt
      121 ttagattgat gaaacaggat tcgatactta tttttatcga gaatatggtc gctcattaaa
      181 aggtcagtta ataagaggca aagtatctgg aagaagatat cagaggattt ctttggttgc
      241 aggtctaaca aatggtgaat taatcgctcc aatgacttac gaagagacga tgacgagcga
      301 cttttttgaa gcttggtttc agaagttttt cttaccaaca ttaaacacac catcggttat
      361 tatagtaaaa tgaaataaga ataggacaaa tcgatcagga cagtaaaatc gaattctaac
      421 aatgttttag aagtagaggt gtactatttt agtttcaatc tactatattc tcaaatttcc
      481 tacgcccgcg atggacaatg caagattcca tagaatgggt aagctagaac ttttatgtga
      541 agagtttggg cataaacttt tacctcttct tccctactca cctgagtaca atcctattga
      601 gaaaacatgg gctcatatca aaaagcacct caaaaaggta ttaccaagtt gcaatacctt
      661 ttacgaggct cttttgtctt gttcttgttt caattgacta tataaattgt ctaagcgaaa
      721 caaccgataa gaattggcac aaaagcgacc gtatttttgt taccaataca ggaaaaccag
      781 ttcatagttc tatcttgagc aagtctctcc agcgagcaaa cgaacgcctt aaaaaaccaa
      841 ttcccaaaca tctgtcccct cacatcttca gacacaccac tattagcatc ttatcagaaa
      901 ataaaattcc tttaaaaaca atcacggaca gggttggtca ttccgactct gaagtcacta
      961 cttccatcta cacccacgtc acaaagaaca tgaaagatga agcaatcaat gtactggata
     1021 aagttatgaa aaagattttt taaaaagttt tgcccctttt ttgtcctcta aatacaaaaa
     1081 tagcccttcg gataaaatcc gaggggctag aaacgttgtt aaatcaacgg ccgaactttt
     1141 gaatttcatg gttcgggata aaatagttca ctgaactatt ttatttttta aggttgtaga
     1201 atgatttcaa tccacgatat tcagctactt caccaagttg gtcttcgata cgaagcaatt
     1261 ggttgtattt agcgatgcgg tctgtacgtg aaagtgaacc agtcttgatt tgtcctgcgt
     1321 tagttgcaac tgcgatatca gcgattgttg aatcttcagt ttcacctgaa cggtgtgata
     1381 caacagcagt gtaaccagct tctttagcca tttcgatagc ttcaaaagtt tcagtaagag
     1441 taccgatttg gttaactttg ataaggattg agttagcagc accttcttgg ataccacgtg
     1501 caaggtagtc agtgtttgtt acgaagaagt cgtcaccaac aagttgtact ttcttaccaa
     1561 gacgttcagt aagagctttc caaccatccc agtcgttttc atccatacca tcttcaatag
     1621 tgatgattgg gtatttgtta accaattctt caaggtagtc gatttgttct gcagatgtac
     1681 gaacagcagc accttcacct tcaaatttag tgtagtcgta aactttacgt tctttatcgt
     1741 agaattctga tgaagcacag tcaaatccaa taaatacgtc tttacctggt acatatccag
     1801 cagcttcaat cgcagcaagg atagtttcaa caccatcttc agttccttcg aaacgaggag
     1861 cgaatccacc ttcgtcacct acggcagttt ccaaaccacg tgatttaagg attttcttaa
     1921 gagcgtggaa gatttcagca ccgtaacgaa gggcttcttt aaatgttggc gcaccaactg
     1981 gcaagatcat gaactcttgg aaagcgattg gagcgtcaga gtgagaacca ccgttgatga
     2041 tgttcatcat tggagttgga agaactttag tgttgaatcc accaaggtag ctgtaaagtg
     2101 ggatttcaag gtagtcagca gcagcacgag ctacagcgat agacacaccg aggattgcat
     2161 tcgcacccaa tttacctttg ttaggagtac cgtcaagtgc gatcatagca cggtcaatag
     2221 cttgttgatc acgtacatcg tagccaatga tagcttcagc aatgatgttg tttacgttgt
     2281 caacagcttt ttgtgtacca agaccaccgt aacgagattt gtcaccgtcg cgaagttcaa
     2341 ctgcttcgtg ttcaccagta gaagctcctg atggaaccat accacgtccg aaagcacctg
     2401 attcagtgta aacttctact tcaagtgttg ggttaccgcg tgagtctagg acttcgcgag
     2461 cgtaaacatc agtaataatt gacatttttt actctcctta tgagttaaat tttttacacc
     2521 tctataatac cttaaaaccc ctcctttttc aagaaaaaac gttatctttg tgcaactttt
     2581 ccttaacttt ataaagtaat cgctttcttt tgtctgtttt attctaactt ttatgatata
     2641 ctgttttcat gacagattta tcaaaacaat tacttgaaaa agctcatggt gggttaaaaa
     2701 taaatccgga tgagcaaaga cgctatcttg gtacttttga ggaaagagtt cttggatatg
     2761 tagatattga cacagcaaat agccctcagt tagaaaaagg ctttttattt attttagaaa
     2821 accttcagga aaaagcagag ccactatttg tgaagatttc accaactatc gaatttgata
     2881 agcaagtttt ctacttaaaa gaagcaaaag aaactgatag tcaagccacc atagtatctg
     2941 aagagcatat tacttctcct tttggcctgg ttattcatag caatgcacca gttcaagtag
     3001 aagaaaaaga ccttcgactt gcttttccaa aactttggga agttaaaaag gaagaaccag
     3061 ccaaaacatc cttatggaag aaatggttta gctaaatctt gcacatattt aataagtgcc
     3121 caatattggc agccgtgcgc tccagataga gactggcatt tttcaaacta tcttctaaag
     3181 gttcactttt ctccaaaata gaaaagacag cttggatatt ttcaaatggt aggggaggta
     3241 aatcttcagc aagactaccg caaatagcaa taacaggaac tccaacaggg gttctttttg
     3301 caacacctat aggcgctttc ccagcaaagc tttgactatc aagtcttcct tctccaacaa
     3361 caaccaagtc agcatctgaa actttcttat caaagttgat taagtccaag caggtatcaa
     3421 ttccagacac gatacttgcc tgagcaaagg cacacaaacc accagcaagg cctccacctg
     3481 ctcctgctcc tttaatttct aatgttgcag gtgagaattt ttcataaaaa tcttggatcg
     3541 cctgatctac gactgcaaac atagtcggat gtagaccttt ttgattgcca aaagtgtaag
     3601 tcgcaccttg atgaccacat aagggactca cgacatctgc tagaatatga atttgaacac
     3661 cttcaggaat tttatagcaa ttttctgttg aaacagaagc taagtctaat aaggattgac
     3721 cggaagcagg caagacattt ccatccctat cataaaattg ataacctaaa ccagcagcaa
     3781 tccccagtcc tccatcatta ctggccgtgc caccaacacc gatataaata tctttaatcc
     3841 ctttagaaat gagatggaga atcaactctc caataccata agtttggatt tgaagtggat
     3901 ttcgtttctc tagcggaatt tttccaagac caaccaagtc agctacttca aatagtgcca
     3961 gttccccttt ttgaaaatag cgcatggctt ctttttgtcc aaaagggtct gtcacttgga
     4021 tccatttttc ttttaggtca agagaatgtc ggatagcatc tacagtacct tctcccccat
     4081 caccaacagg gcagaggaga tattctacat ctgctatcga ttgttggaag cctcttttta
     4141 ttgcttcagc tacctgttga gctgtcaagc tttccttaaa cgaatctggt gcaattacaa
     4201 tcttcatatt ttccctcatt ctaaacagtc aatcaaagga agaacttcta aaaaatccct
     4261 cttgtcaaca tgatgtggta tttctttttt gagcacttct ttggcacaaa aggcgattcc
     4321 taactccgcc gacttcaaca ttaatagatt attgacccca tcaccgattg ccaccgttct
     4381 ttctttagaa agttttagtt tctttctcca tttttccaga gtctcttttt tgacctgggg
     4441 acttataatt tgttcaacta attttcctgt taaaagacct tctttgactt caagctggtt
     4501 ggcagtgaaa taggcaatac caagggattt tgctaatctc tccaactatt ggtatccacc
     4561 agacaccaca caccagacca actaggatgc cattcttttg gagaatagag atgaactctg
     4621 ggacatttag cgatagatga attgagttga agacgttatc aaagaccaaa ataggaagac
     4681 cttccaacaa ggacactctt tttcttaaac tgctttcaaa gaccaactct cctcgcattg
     4741 cccgacttgt aatctgcgaa atttccgcct catgacctgc ctctctccct aaaagatcaa
     4801 tcacttcttc taggattaag gttccatcta catccaaaac acacaagcct tttacttgag
     4861 acatcagttc tcctctctaa acagcctaaa aatcgtatga agtcatcata cgattttatc
     4921 tattaattaa ctaaactatg gtacaagtca aggtatgact tgcaggctgt atcccatgag
     4981 aagtcactct ccatagcttg tttttgtagg tttctccaaa tgtctggatg gtttctatac
     5041 aagtccaatg ctgtttggaa agtccaattt aaccaataag gagatagatt gtcaaagcta
     5101 aagccagtac cgcttccttc gattggattg aaagcgcgaa ctgtatctcg caagcctcca
     5161 acttcatgga ccaatggcaa ggttccataa cgcatagcca tcatttgaga caagccacac
     5221 ggttcaaaac gacttggcat gaggaagagg tcacaagcag cgtagatttc ctgagcaagt
     5281 ttgacatcaa aagtgatatt tgctgatagc ttgtctgggt aaatctgagc aaaccatgag
     5341 aaagctcctt caaaggctgg atcgccagtt cccaaaagaa caatctgaac atcttcttgc
     5401 aagatatggt gaagactttc gaccaccaca tcaaaacctt tttgacgtgt caaacgagaa
     5461 acaattccca ccagtggaac gtcagctcta acaggaaagc caactctttc ttgcaatttt
     5521 gccttatttt tggctttccc agacaaatct tcctgattga aatgatagtc taaaagagca
     5581 tccgtctgag gattataaag atcagcatca atcccattca cgataccaga tactttacca
     5641 gactccattt taagaatctg atccaaatta catccaaact gactagtcat aatttcatga
     5701 gcatagctag gtgaaacggt tgaaacacgg ttcgcataga gaatacctgc cttcatccag
     5761 ttcagacagt tgttccatcg aagggtgcca tcagcgtaac gttcaaagcc aactccaaac
     5821 aaatcaccca acattccttc tgaaaattgt ccttggaatt ctaaattatg aatggttaaa
     5881 actgtttcaa tgtcctcata ggcttgaatc caacggtatt tttccttcaa caagaaagga
     5941 atcatagctg tatggtagtc atgaacatgg agaagatcag gaataaagtc aatcctttcc
     6001 atagcctcaa tggcagccag ttggaaaaag gcaaagcgtt ctccgtcatc aaaatcaccg
     6061 taaacatgac cacggaagaa ataatattga ttgtcaataa agtagaaggt tacaccattt
     6121 aatactgttt tcttaattcc acaatactgt ctgcgccaac caacgctcac ctcaaaatga
     6181 agcacatctt caatctgatt tccaaattta gcctctacca tatcatagta gggtaaaatc
     6241 actgcaactt cgtgcccagc ttttaccagt gattttggaa gagcgccaat gacgtctccc
     6301 aaaccacctg tttttgaaaa gggtgcaccc tctgctgcta caaataaaat tttcatgaat
     6361 gaatatcctc tgttacttta gcacttttct taaccacaac tggatgttct gcagttcctc
     6421 gaatcacaac accaggctca acttcaaccc ctttgtccaa gatagcatat tcgacctgag
     6481 ccccttctcc aataacaaca cgagggaaga gcaggctatc tttaaccaag ctatccttat
     6541 gaacatgaat attacgtgat agaacagaat tagctacttg accttcaata atactaccag
     6601 aggcaaactg agaagtgctt accttagatg tattagcata gtaagttggc tcttcgtttt
     6661 tgacctttgt ataaatcttt tggtttggtg agaaaagaga atagaatttt tgtgattcaa
     6721 gcatatcgat attcgcttga taataagatt taacagagtg aatattggct agatagcccg
     6781 tgtactcgta ggcgaaagct ccctctttta cagccaaatc ccgtaaaaca tagcgcaatt
     6841 tctctggatg ttctttttta gcttcttctt ccaagtgttc aatcaaccaa ggtgtatcaa
     6901 cgacaaagat atctgtagac atattgaacg tttcagctgt tgacttgcta tcaaagagtt
     6961 tatgagaaag aacatggtct gtttcatcta catccaagat tgcatttact tctgaaatat
     7021 ctttcttagc tagtttttta taaactacag tgataggctc ttttgttgta ctatgtaggt
     7081 ggaaaacttg gttcaaatca atgttaataa gaacatcgca gttgagggca accgtttggt
     7141 ttgagccaga acgtttcaaa taagtaagaa gctgttggta gtattctttt ccaactgtac
     7201 tactttctac acgggtattg taaattccta gatagtaatg gctaagaagg gttgataagc
     7261 cccactcgcg tcctgaacga atatggtcaa atactgagct gatattatcc tgctggaaaa
     7321 taccaaagac actacgaaca cctgcattag caaggcttga aagtgggaaa tcaatcaaac
     7381 gatatttccc accaaatggc aaacttgcta ctggacggtg gtccgtcaat gtcgacatat
     7441 tgtgaaaacc aactgtattt cctaaaatgg cagaatattt atcaatcttc atctgttgct
     7501 acccccacta cttcattata tcctacaact tgtacttcat ctgttccatc aatttcgaca
     7561 ccgtcagaaa taatcgcacc ttcaccaata atggcacgtt taatcttagc tccttgacca
     7621 atgatagctc cactcatgat aactgaatca aggacttccg ctccttcgcg aacttgcgcg
     7681 cctgttgaaa ggatagaatg tttaacagtt ccatcaacga aacatccgtc tacaactaat
     7741 gagtcttcca catgagcatt tgccccgagg aagtttggtg gtgaaatcaa gtttcttgag
     7801 taaatcttcc attgacggtt acgactatcc aaggcatttt ctggagaaat atactccatg
     7861 ttcgcttccc aaagtgactc aatagtacca acatctttcc aataaccact aaattcgtaa
     7921 gcataaacac tttcacctaa ctcaaggtaa tttggaatga catttttacc aaagtctgac
     7981 atgccaacct tgctcttttc agcagcgact aacatattac gaaggcgttg ccaatcaaaa
     8041 atgtagattc ccatagaagc ttttgtagat ttaggttgag ctggtttttc ttcaaattca
     8101 acaatacgat tgttagcatc tgtgttcatg ataccaaaac ggcttgcttc tttaagaggg
     8161 acgtctaaaa ctgctactgt caagctggca ttattatcct tatgagactg gagcatatca
     8221 tcatagtcca ttttgtagat gtgatcccca gacaaaatca agacatactc aggattgaca
     8281 ctgtcgatat agtcgatatt ttggtaaata gcgtgactag tcccctcaaa ccaacgattt
     8341 ccttcacttg cagaataagg ttgaagaata gagacacctg aatcaatacc gtctagtccc
     8401 cagcttgaac cattcccaat atggttgttg agagcaagtg gttgatactg tgtaacgacc
     8461 ccaacattgt gaatccctga gttggcacag tttgataggg caaagtcaat gatacggtag
     8521 cgcccaccaa attgcacagc tggttttgcg atgctttgag tgagtttagc gagacgagtt
     8581 ccttgcccac cagcaagaat caaagctaac atttcatttt tcattttcta ctcctttttg
     8641 gtttttattt gtgacggttt tagtagattt caagcgacgt ttgattttcc atacacttgc
     8701 tcccatagcc ggtagggtaa aggttaaggt ctgctcataa tctttccata gtccttcttg
     8761 cgtttgaaca gttttattat gttctttcca aacgcctccc cactcttcca actcagtatt
     8821 ccatacttct tcgtaaattc ctgcaacggg tagtccgatt gtaaaatctt tccgctcaac
     8881 aggtaccata ttaaagatac agactaacat ttctcccttt ttacccttac gaataaagga
     8941 aagaacactc tggtctcgat tatccgcatc aatgatttca ataccatcat agctggtatc
     9001 aatttcccac agacagcgat gatctctgta aaactggttt agctgagaag tgaaatactt
     9061 catcttagca ttcattgggt cttctaggtt agaccattcc aactgttctt cagatttcca
     9121 ttctaggaat tgaccgtatt cgctacccat gaagagcaat ttcttaccag ggtgacaaat
     9181 ttggtacgta tagagattgc gcaagcctgc gaattgattg taacgatctc cccacatctt
     9241 atgcatcata ctcttcttgc catgaaccac ttcatcgtgc gagaatggca agagataatt
     9301 ctccttgaaa acatacataa agctgaaagt caccaggtta aagtcatatt tacgataaat
     9361 cggatcttct tcgtagaaac ggaggatatc attcatccag cccatgttcc atttgtagtc
     9421 aaatcctaga ccaccaatct ctttcattcc cgtaatcttg gttgcagacg aactttcttc
     9481 tgcaatcatc atcacatctg gatattctaa cttaataact tcattcaagc gttgaaggaa
     9541 ataataacct tcatagttga gatttccgcc atctttatta ggtgtccatg gagcatcatc
     9601 atagtccaaa tagagcatgt tgctaacagc atccacacga ataccatcca aatgatagac
     9661 atcaatccaa tgcttaatgc aagaaattaa gaaggactgg acttcatttt ttccaaggtc
     9721 aaaattaagg gcaccccaac catggttatg agccttatta tggtcttggt attcaaaagt
     9781 cggtgtccca tcataataag ctaaggcatc atcgttgatg gtaaagtgac ctggtaccca
     9841 gtccacaata accccaatat tatgggtatg acactcctcg acaaaatctt gaaactcctc
     9901 tggtcggcca taagcatgct ctaaagcgaa gtaacccata agctgatacc cccaactcaa
     9961 gcccaaagga tgggacatca agggcataaa ctcaatatga gtatagttca tttcaacgag
    10021 ataaggaatg agttcatcct tgagctgggc aaaactataa ggactgccat cagaatttct
    10081 tttccatgat ccagcgtgaa cttcataaat attgacagga cgctcttcaa agccccaacg
    10141 ttttcttcgt gccagccaaa gtccatcctt ccatttcttc tcaggaagct ctgttaagat
    10201 tgcccctgtt cctggacgag cctcatatct gacagcaaaa gggtcaatct tcatcagttg
    10261 atgaccattt tgacgtgtga catgatattt gtaaatatgc ccttcttgag ccatattggt
    10321 aaagacttcc cagaccccaa aatcatttct taccattgga atctgatttt caatccagtt
    10381 ggtaaaatca ccaaccaagt gaacagcctg agcattaggt gcccaaacac ggaaggtata
    10441 gccatgctct ccatttagtt cttccctatg tgctcctaga taatgttgga gataaaaatt
    10501 ttcacccgtc ataaaggttt ttaatgcttc tctattatcc atatactccc cttctcctgt
    10561 aagcgttttc tatgctttta ttatactacc tttttagaga agattcaagt aaattactat
    10621 acttctttaa ttattttgaa aatctacaac aagttcactt actcgttcaa ttgtaaatca
    10681 atattttttc aaaaaattgc gaaaacacct ttctttttct a
//
LOCUS       DAVLHB010000060        10551 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLHB010000060 DAVLHB010000000
VERSION     DAVLHB010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10551
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.060"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(68..592)
                     /locus_tag="VXE36_001842"
     CDS             complement(68..592)
                     /locus_tag="VXE36_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0780087.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAVDCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(645..881)
                     /locus_tag="VXE36_001843"
     CDS             complement(645..881)
                     /locus_tag="VXE36_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0780088.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLVK"
     gene            complement(949..1869)
                     /locus_tag="VXE36_001844"
     CDS             complement(949..1869)
                     /locus_tag="VXE36_001844"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0780089.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            2059..2462
                     /locus_tag="VXE36_001845"
                     /pseudo
     CDS             2059..2462
                     /locus_tag="VXE36_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2678..3259
                     /locus_tag="VXE36_001846"
     CDS             2678..3259
                     /locus_tag="VXE36_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0780090.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            3256..4533
                     /locus_tag="VXE36_001847"
     CDS             3256..4533
                     /locus_tag="VXE36_001847"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0780091.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            4551..5213
                     /gene="deoC"
                     /locus_tag="VXE36_001848"
     CDS             4551..5213
                     /gene="deoC"
                     /locus_tag="VXE36_001848"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0780092.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            5200..5589
                     /locus_tag="VXE36_001849"
     CDS             5200..5589
                     /locus_tag="VXE36_001849"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0780093.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5679..6731
                     /locus_tag="VXE36_001850"
     CDS             5679..6731
                     /locus_tag="VXE36_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0780094.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6875..8410
                     /locus_tag="VXE36_001851"
     CDS             6875..8410
                     /locus_tag="VXE36_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780095.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            8403..9461
                     /locus_tag="VXE36_001852"
     CDS             8403..9461
                     /locus_tag="VXE36_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0780096.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            9464..10420
                     /locus_tag="VXE36_001853"
     CDS             9464..10420
                     /locus_tag="VXE36_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0780097.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3008 a         1877 c         2411 g         3255 t
ORIGIN      
        1 taggctccat aatatccata ggggatttac ccactacaaa tattatagag cccaaaaagg
       61 aagcccttta tgaattgtag gacttccttt tcttatccag aaattgatct agctctctct
      121 gatttcgaag aatagtgact ttatgtgaat attcttggca aagtttttgg taattttctt
      181 tttgagtttt gctacgccca tcccaaagaa tccatctgat aaactcccac tcaaagcgtt
      241 cagggcaatc taccgccata ctttctctga cttttccacg gtatttaaga taacgcttaa
      301 aggctctaaa gagacaggtc aatggcgaaa aattgagaaa gatgatttgg tcagcttctt
      361 gcattcgttc ttggtagtag caccaagaat aattaccatc gatgacccaa gctttatgct
      421 tggtgagaaa gttttttatc tcggttaaca tccattcgca gtcactgtct tgccaaccag
      481 gttgaaattg gagtgtgtcc atgtgcagtt ttggaatgga gtagtagtta gataactttt
      541 ctgctatagt tgacttacca gaaccagaat atccgataat tgcgattttc attttctacc
      601 ttttcctatt tggagacaaa aaaacagcct ctatggactg tttcttattt aacaagttta
      661 gctgaaagac gagctttatc gcggcttgct ttgtttttgt gaatcaaacc tttagtttct
      721 gctttatcga tagctgagct agcagcacgg aaaagttctt cagatgggtt tgcttcgaaa
      781 gcttttatag cagtacgcat agctgatttt tgagctgagt tcttttcgtt ttgtttaacg
      841 ttcaattcag cgcgtttgat agctgattta atgtttgcca atgttcttac ctccatattt
      901 actaactata ccattatata tgaaaactta cgttttgaca agggaaaatt acttttttaa
      961 gtaaatttca tcgatttcat ggttcttgct tttatgaaga atcacttctg cacgatttct
     1021 ggttggttca atataatttt gtagatttgt gagattgata ctggtccaga cctgatgggc
     1081 aaaggcttcc acttccccaa tcggcatctg agtaaaacga taatagtagc tatcagggtc
     1141 gttttgggct agactcagca ttttcaagaa acggtccaga taccaacttt caatatcatc
     1201 cactccagca tctacataga tggaaaagtc aaagaagtca gtgatataga gacgatcgtt
     1261 ttgtggattt tgaaagacat tgattccctc aacaattaca aaatcagcag ctttgacact
     1321 ttgtttctct tcgggtacga tgtcgtaaac ttcatgagaa tagacaggaa tatctacatc
     1381 ttgtccattt ttgatgcggt ccaagaagtt gagaagagct tccatatcat agctttcagg
     1441 aaatccttta cgatttaaaa tcccctgctc aatcaaggtt tgattgggat agagaaaacc
     1501 atcagttgta accaactcaa ccgtagcatc tgtaaacgta cgggacagta ggatttgaag
     1561 taggcgactg gttgtggatt ttccaacggc aacactccca gaaaccccaa taataaaagg
     1621 ttgagattta ctttcacgtt ggaggaaaat tccttttgaa aaggctaaat cttccttagt
     1681 tcgcttgtaa atctgaatca gatgagccaa ggggagatag atatctgtaa cgtcttggag
     1741 actgatttgg tcattaaaac tcttgataga ttccaattct tcttctgtca aaggaggtgt
     1801 tgtctttcga tgtaaagatt gccaagtctg gcggctgatt ttttcaaaat gtaaaaattc
     1861 gttggtcatt tgttttcccc tagatatttt gtctatcata ccataaaaag ctaaaaaaat
     1921 aaagcggttt cttgaatgtg gtaagtcaat ggtatatagt ataagtgatc aatttattga
     1981 tgaaatagga gatagattct actgatttat aagcttataa agggggcttt ttagttcaca
     2041 acttatagga ggtgtactat gaaaatctta aaacgttaca tattggaact ctgttttatt
     2101 ttaagttttg ctttaccttt tataaaagga accaatgcag ataatggtag atgctttgtg
     2161 gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc tgtctttatt
     2221 tgttcgttct taattgcttt cttactaaaa aacgatggac gaaatggatt gctgcgggta
     2281 gttattgctt tttagtccta cggattgcga cagagggtta tttcttccac atgtcactag
     2341 aagatttgat acgactttgg acaagtttgg aaatcctgac acaaacgtat cagttgggct
     2401 tttatctaaa cattttgtta ggaattttgt tgataataaa gtattttaag gttaagcaat
     2461 agaaataata atctgcctga ttatagatga taaacttttt gtttttatct ggactgtgat
     2521 atttatagtt ctaaatggtt tattatttat aagtgttgaa agagattgaa gaaaatggct
     2581 tcgtgacttg ctttcttcgg tctttttcgt tttattatca atttgtaaac gatttacaat
     2641 ttgagtcaaa ttatggtaaa atagtgtcat gagtaaaatg tactatgcag aaaatcctga
     2701 cgctgctcac gacattcatg agttgagagt ggacttgttg ggagaaaaaa tgactttttt
     2761 gacagatgcg ggtgttttta gcaagaaaat ggttgacttt ggaagtcaac tcttgctcaa
     2821 gtgtctggat gtcaaccaag gagagacagt cctagatgta ggctgtggtt atggtccatt
     2881 aggtttgtcc ttggtcaagg tttacggagt tcaggcgacc atggttgata ttaacactcg
     2941 tgccctggat ttagctcaga gaaatgctga aaaaaataat gcaaaagcga cgatatttca
     3001 atctaatatt tatgcaagag ttcaagggcg atttgaccat gtcatttcca atcctcctat
     3061 ccgtgcgggc aagcaagtcg ttcatgaaat catcgagaaa agtaaagatt tcttggaaat
     3121 tggtggagat ttgaccatcg tcatccagaa aaaacaagga gctccaagtg ccaagtctaa
     3181 gatggaagat gtgtttggca attgtgaaat ccttaaaaaa gacaagggat actatatcct
     3241 tagaagtgtg aaagaatgag agcagttgat ttaatccaaa aaaaacgaga cggtcaagaa
     3301 ctgacttcaa gtgaaattga atggctgata gaaggctatg tatcaggaac tgttcctgat
     3361 tatcagatgt ctgcctttgc tatggctgtt tattttaaag gaatgacgac tcgagaaatc
     3421 tctgatttaa cgatgaatat ggttaagact gggcaagagt ttgacctgtc agccattgat
     3481 ggtgtgaaag ttgacaagca ttctactggt ggtgtcggcg ataaggtaac cttgatttta
     3541 gctcctcttg ttgctagctt cggtgtgcct gtagcaaaaa tgagtggtcg tggtcttggc
     3601 catacaggcg gaacaattga taaattggag tccattaagg gctatcaagt agaacgtagt
     3661 caagaggatt ttattcgtca ggttcaggat attggagtat ctgtcattgg gcaatcagac
     3721 cagctggtca aagcagataa gcttctctat gcccttcgtg atgtgaccgc aactgtcgac
     3781 acgattcctt tgattgcgag ttcggtgatg agcaagaaaa ttgcggcagg ggcggatgct
     3841 attttgctag acgtgactgt cggtgagggt gccttcatga agacggttga tgaggcgcgt
     3901 gagttggctc aaactatggt agatcttggt aaggttgttg gacggaagac agtagcagtg
     3961 attacggata tgagccagcc tttgggacga gcgattggaa atcgtctgga aatccttgaa
     4021 gcattggaga ttttgcaagg tcaaggacgt caggatatta cccactttat ttgtgaattg
     4081 gctcaaatta tgcttggttt ggcaaatgtt aacaaaactg ttgaagaagt tcaccaacat
     4141 cttgagaatg gtcaagcact ggctaagttt gaggaaatgg tgcaagccca aggtggagac
     4201 ttggaagacc tctatcgtcc tgtaaatgta gctcatgtgg tggaaatccc tgctcaggaa
     4261 acgggtgtca tttcagctct tccagctatg gactttggtc tttatgccat gaggctgggt
     4321 gctggtcgtg cagttaagtc tgatgccttg gactatgaaa caggaattgt ttttgaaaag
     4381 aagattggag actccgttca aaagggtgaa attgttgcaa aagtatacac aaatgaaaaa
     4441 attccacctc aactagttac agatttccaa aaatgtgtta aaataagtga tgaagtgaaa
     4501 aaaatccgtg aaattgtaga aatcatctcc taaatggagg gaaaaccgaa atgaaattaa
     4561 ataaatatat agatcatacg cttttaaaac aagatgcaaa gaaaaaacaa attgatagtt
     4621 tgttgtctga ggctagagag tatgactttg ccagtgtttg cgttaatccg acctgggttg
     4681 aacatgctaa aaaaggactt gaaggcacag atgttaaggt ttgcacagta gtaggtttcc
     4741 ctttgggagc aacaacttca gccgtgaaag catttgagac aaaagaagct atccaaaatg
     4801 gtgcagatga gattgatatg gtgatcaatg ttggagctct caaatcaggt aatttagcct
     4861 tggttgagtc agatattcgc gcagtagtgg aagcaagtgg tgataagtta gtgaaagtca
     4921 ttattgaagc ttgccttctg acagaccaag aaaaagttgt tgtttgccaa ttggcccaaa
     4981 aagctggggc tgactttgtt aaaacatcta ctggtttttc aactggtggt gctacgatag
     5041 cagatgttac attaatgcgt gaaacagttg gatctgatat gggagtcaag gctgctggtg
     5101 gagctcgttc ttatgcagat gctcttgcct ttgtcgaagc aggtgcgacc cgtatcggaa
     5161 cgtcagctgg ggtagctatt ttaaaaggag aattggcaga tggcgactac tgagttgatt
     5221 gaactggcaa ttgaaaccag caaacatgca tatgtcccct attctcactt tcctatcgga
     5281 gcagttttag tagccaaaga cggaagtgtt tacacgggag tgaatatcga aaatgctagc
     5341 tatcctttga ccaattgcgg tgagagaaca gctattttta aggctatatc tgaaggccaa
     5401 agagaatttt cagaattgat tgtctatggt caaactgaaa aaccgatctc gccatgtggt
     5461 gcttgtcgcc aagtgatggc tgaatttttt gaacaagatc taaaagtgac cttagtcgca
     5521 aaagataaat cgacggtcga gatgacggtc ggggaattac ttccatactc ttttacagac
     5581 ttaaactagt ctgagtcgct ctctgagtgg cacggtcctt gtggccaacc aatccatact
     5641 tgcaacatcg ttgcacatct tatttaggag gttcagtaat gaacaagaaa caatggctag
     5701 gtcttggcct agttgcagtg gcagcagttg gacttgctgc atgtggtaac cgctcttctc
     5761 gtaacgcagc ttcatcttct gatgtgaaga caaaagcagc aatcgtcact gatactggtg
     5821 gtgttgatga caaatcattc aaccaatcag cttgggaagg tttgcaggct tggggtaaag
     5881 aacacaatct ttcaaaagat aacggtttca cttacttcca atcaacaagt gaagctgact
     5941 acgctaacaa cttgcaacaa gcggctggaa gttacaacct aatcttcggt gttggttttg
     6001 cccttcataa tgcagttaaa gatgcagcaa aagaacacac tgacttgaac tatgtcttga
     6061 ttgatgatgt gattaaagac caaaagaatg ttgcgagcgt aactttcgct gataatgagt
     6121 caggttacct tgcaggtgtg gctgcagcaa aaacaactaa gacaaaacaa gttggttttg
     6181 taggtggtat cgaatctgaa gttatctctc gttttgaagc aggattcaag gctggtgttg
     6241 cgtcagtaga cccatctatc aaagtccaag ttgactacgc tggttcattt ggtgatgcgg
     6301 ctaaaggtaa aacaattgca gccgcacaat acgcagccgg tgcagatatt gtttaccaag
     6361 tagctggtgg tacaggtgca ggtgtctttg cagaggcaaa atctctcaac gaaagccgtc
     6421 ctgaaaatga aaaagtttgg gttatcggtg ttgatcgtga ccaagaagca gaaggtaaat
     6481 acacttctaa agatggcaaa gaatcaaact ttgttcttgt atctactttg aaacaagttg
     6541 gtacaactgt aaaagatatt tctaacaagg cagaaaaagg agaattccct ggcggtcaag
     6601 tgatcgttta ctcattgaag gataaagggg ttgacttggc agtaacaaac ctttcagaag
     6661 aaggtaaaaa agctgtcgaa gatgcaaaag ctaaaatcct tgatggaagc gtaaaagttc
     6721 ctgaaaaata atggatggaa gtcatttctt aggaagcggc caagggccgc ttttttaaga
     6781 gttgagacaa agtcattttg tctcagtaaa gcttgctact agacaaacta gcaagtttta
     6841 ttgaaataaa ataagactct gaaaggaaga gcacatggca cacgaaaatg tcattgagat
     6901 gcgtgatatt accaaggtgt ttggtggatt tgttgccaac gacaaaatca acttgcacct
     6961 acgaaaaggt gaaattcatg cacttttagg agaaaatggg gctggtaagt ccacgctaat
     7021 gaacatgtta gcaggccttc ttgaaccaac tagtggtgaa atcgcggtca acggtcaagt
     7081 tgtcaatctc gactccccat ctaaagcagc tagcttggga atcgggatgg ttcaccagca
     7141 ctttatgttg gttgaagcct tcacagtggc tgaaaacatc attttaggta gtgaattgac
     7201 taaaaatggt gtgctagata tcgctggagc tagcaaagaa atcaaggctc tttctgaacg
     7261 ttatggctta gctgttgacc cttctgccaa ggtagcagat atctcagttg gagcccaaca
     7321 acgtgtagaa attttaaaaa cactttatcg gggggctgat atccttatct ttgacgaacc
     7381 aacggctgtt ttgactccat cagaaattga tgagttgatg gctattatga aaaatcttgt
     7441 caaagaagga aaatcaatta tcttgattac ccacaaattg gatgaaattc gcgcagtttc
     7501 tgaccgtgtt acagttatcc gtcgtgggaa atcaattgaa accgttgaaa ttgcaggggc
     7561 taccaatgct gatttggcgg aaatgatggt aggacgttct gtttccttta aaacagagaa
     7621 gcaagcctct aaaccaaaag aagtggtttt gtctatcaaa gatttggtgg tcaatgaaaa
     7681 ccgtggtgtt ccagctgtta aaaatctgtc cttggatgtt cgtgctggag agattgttgg
     7741 tattgcgggg attgatggaa atggtcagtc tgaactgatt caagccatta caggtcttcg
     7801 taaggttgaa tctggtagca ttgagctaaa aggggattca attgtaggct tgcacccacg
     7861 tcagattaca gaactaagtg ttgggcacgt tccagaagac cgtcaccgtg atggcttgat
     7921 tttggaaatg atgatatctg aaaatattgc ccttcaaacc tactataaag aaccacatag
     7981 taaaaatgga attttgaatt attcaaatat tacttcttat gctaaaaagc tgatggaaga
     8041 gtttgatgtt cgcgctgcca gtgaattagt tcctgcagct gcactctcag gaggaaatca
     8101 acaaaaagca attattgctc gtgaaattga tcgagatcct gatctcctta tcgttagcca
     8161 gccaactcgt gggttggatg tcggtgccat tgagtatatc cacaaacgct tgattgaaga
     8221 gcgtgataat ggcaaggctg tccttgttgt cagctttgaa ttggatgaga ttttaaacgt
     8281 ctcagaccgt attgccgtta tccacgatgg taagattcaa ggtattgtat caccagaaac
     8341 aaccaataaa caagaacttg gtgtcttgat ggctggtgga aacttgggaa aggagaagag
     8401 tgatgtttaa aaaattacaa caaatttcgg ttcccttgat ttctgtattt ctaggaattt
     8461 tactcggagc cattgtcatg tggatcttcg gttatgatgc tatttggggc tacgaagaat
     8521 tgttctatac agcctttggc agtctgcgtg ggattggaga aatcttccgt gctatgggtc
     8581 ctctggtctt gattggtctt ggttttgcgg ttgccagtcg agctggtttc tttaacgtcg
     8641 gacttcctgg tcaggctttg gcaggttgga ttctcagtgg ttggtttgcg ctgtcgcatc
     8701 cagatatgcc ccgtcccttg atgattctag caaccatcgt gattgccttg attgctggtg
     8761 ggattgtcgg agcgattcca ggtattctta gggcctatct agggacgtca gaggttattg
     8821 taaccatcat gatgaactac attgtcttgt atgtagggaa tgcctttatc catgctttcc
     8881 ctaaagactt catgcaaagt acagattcga ccattcgtgt tggggctaat gcaacctatc
     8941 agacaccttg gttggctgag ttgactggta actcacggat gaatattggt attttctttg
     9001 ccatcattgc tgttgcagtt atttggttca tgctcaagaa aacaactctt ggttttgaaa
     9061 tccgtgcagt tggtcttaat ccacatgctt cagaatatgc tggtatttct gccaagcgga
     9121 ctattatcct atctatgatt atttcaggtg ccttggcagg tcttggtgga gctgttgaag
     9181 gtttgggaac cttccagaac gtctatgttc aaggttcgtc attagctatc ggatttaacg
     9241 gaatggcggt tagtttgctt gcggccaact caccaattgg tatactcttt gcagccttcc
     9301 tatttggcgt tctccaagtt ggggctcctg gtatgaatgc ggcgcaggta ccatctgagc
     9361 ttgtcagcat tgtaacagcg tctattatct tctttgtcag tgttcattac cttatcgaac
     9421 gctttgttaa accgaaaaaa caagttaaag gaggtaagta aagatgtcta ttataacctt
     9481 gctccccctc ttggtgtctt ctatgctgat ttactcagca cctctcatct ttacaagtat
     9541 cggtggtgtt ttctctgaac gtggtggtgt ggtaaacgtt ggccttgaag gaattatggt
     9601 tatgggtgcc ttttctggag ttgtctttaa ccttgaattt gcagaacaat ttggagcagc
     9661 aactccatgg ctatccttgc ttgtagcagg attggttggt agtgttttct ctatcatcca
     9721 cgcagcagcg acggttcatt tccgtgcaga ccatgttgtc agcggtacgg tattgaactt
     9781 gatggcgcct gccttggctg ttttcttagt taaagttctt tataacaaag gacaaaccga
     9841 caacctaagt caaacttttg gacgctttga tttcccagtc ttggcaaata tcccagtgat
     9901 tggtgatatc ttcttcaagt caactagtct acttggttat ctggcgattg ccttctcatt
     9961 ccttgcttgg tttattctct ttaagactca atttggtctt cgtctccgct ctgtcggtga
    10021 acatcctcaa gcagcggata ccttgggaat caacgtctac aagatgagat atttaggggt
    10081 tattatttca ggttttctag gtggaattgg cggagcgatt tatgcgcaat caatctcagt
    10141 taacttctca gtgacaacta ttgttggacc tggatttatc gcccttgctg cgatgatctt
    10201 tgggaaatgg aatccaatcg gtgctatgct ttctagtctc ttctttggac tttcacaaag
    10261 tttggctgtt atcggttctc aattgccgtt tctacaagga gtgccagcgg tttatcttca
    10321 aattgcacct tatgttttga caattcttgt cttagcagcc ttctttggaa aagcagtcgc
    10381 accaaaagca gatggtatca actacatcaa atcaaaataa gcatacaaaa aaacgtcagt
    10441 ccaatgactg aactgccccc caaaagttag acagaaaaaa tctaactttt ggggtgtttt
    10501 tattatgaaa ttaagttatg atgataaagt tcagatctat gaactaagaa a
//
LOCUS       DAVLHB010000061         9901 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLHB010000061 DAVLHB010000000
VERSION     DAVLHB010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9901
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.061"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(177..1592)
                     /locus_tag="VXE36_001854"
     CDS             complement(177..1592)
                     /locus_tag="VXE36_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0780098.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1605..3443)
                     /locus_tag="VXE36_001855"
     CDS             complement(1605..3443)
                     /locus_tag="VXE36_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0780099.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPCVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3461..4300)
                     /locus_tag="VXE36_001856"
     CDS             complement(3461..4300)
                     /locus_tag="VXE36_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0780100.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4600..7159)
                     /locus_tag="VXE36_001857"
                     /pseudo
     CDS             complement(4600..7159)
                     /locus_tag="VXE36_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            7631..8891
                     /locus_tag="VXE36_001858"
                     /pseudo
     CDS             7631..8891
                     /locus_tag="VXE36_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(9007..9810)
                     /locus_tag="VXE36_001859"
     CDS             complement(9007..9810)
                     /locus_tag="VXE36_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0780101.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
BASE COUNT         3326 a         1993 c         1465 g         3117 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 attaatcccc ctataaaata aagaggttta gaatttgatg tcttccaaac ctctttattt
      121 catatttaat gagatgctgc cttaaccgtg ataatatcta atcatcaata aacaaactat
      181 ttgaataagg attctccatt tgattcaatc actcctttat accaagtaaa ggacattttc
      241 ttatatcgat tgaatgtgcc atttccatca tcatttcgat caacataaat gagaccgtac
      301 ctcttagaaa gctgtgcagt ggacatagaa acgcagtcaa tacatcccca agacgtatag
      361 cccataattt ccacaccatc ttgtagagct tcagctactt gcaataaatg ttctttcata
      421 tactgaattc tataatcatc ttggactgtt aagttattaa attcatcttt tattagttga
      481 tctttagcac ctaatccgtt ttccactata aataatggaa tttgataacg gtcataatat
      541 ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc agaagactct
      601 aaataaggat ttactaaacc accaataata ttcccttctc ctgaattata ctgtgttgga
      661 agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac agtataattt
      721 tttaataact ctgcatcttc agctgcaaac tctatgttaa tgtcattttc cttaaaatat
      781 ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga
      841 ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc
      901 atagctaata ccatacaccc caccttaaac tctgaattaa tctcacgagc aatttttgta
      961 accaaactcg aggcaactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga
     1021 ttctccttag gtatatctat tcctccacta gtaaacggta attccaaaac agagtttact
     1081 tcgttaaatg taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca
     1141 aatttttcat aaaaatgaat cattctccta tcaatccatc catgatattt tcttgctaaa
     1201 tataatggag tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt
     1261 tcatcaaaca attcatcata atatttcaac ccagcttcgt taggttcttc ctcatctcct
     1321 tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa
     1381 aacaaggata tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta
     1441 tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact
     1501 gataagccct taccatcttc attatatgct ccctctactt gattagctgc aacagctcca
     1561 ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt
     1621 aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca
     1681 ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc
     1741 aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta
     1801 ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca
     1861 ccctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca
     1921 tcaaatggtg cataaacctt accttcactt ggaataatcg ctactccgtc tccaattagt
     1981 ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga
     2041 gaaaatatca tttttttatt tgaaactcca gctttaactt ctaaattgct agaactctct
     2101 tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga aatgaccgcc
     2161 acaattaaag catttacaat atttgatggc acatcagaat aaataaattg aggcaacgct
     2221 atcaaagatg ggacagcaaa tagatatgct ttaacactag taagacctgc aaataatccc
     2281 gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca
     2341 tataatgcag gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt
     2401 tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct
     2461 aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc
     2521 aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca
     2581 ccaagaatag ctaatgtaag ccatccagct acaccataca tttgcccaac tagatttgat
     2641 aatccttcac caacaattac tccaataggt ccgactacaa ctaaggcaat acagcttgat
     2701 actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa tagctggtgt taatttagca
     2761 attatttttt caatatattt catcaaccaa accataataa gaattggaac gactgatgaa
     2821 ccataactag ctggtgtcac aggtgcacca aataaactaa gaggattccc tgattgcacc
     2881 atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt
     2941 acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca
     3001 tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt
     3061 ggtaaaatga ttaccaagac tttcaacata cctcccccta acattgctgg aatgattgga
     3121 gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga
     3181 acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca
     3241 tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat tacacatggt
     3301 atcttcttca catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt
     3361 gttacacaat gggtaactct attgacattt ttttcacctc caattacatc gaggattttt
     3421 tgtaccgtat ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta
     3481 agcgacgaat atgagccatc aaataaacta attcactaga agtcagcaaa taattgtact
     3541 ccgtttgtat aaacattgcc acctgttcac cacattcata ttctctagga tatttatttt
     3601 tcattaatgc taacaagtct tcatcatcat cgtcacaata agttgtattt tcaaccaagc
     3661 gatgggcaaa taattttata tgagttatga atctataata atcaatagaa tcttggttaa
     3721 actcagtaca atagaaatct tgaatgattt tctcaattcc cataattatt tcagtgattt
     3781 tatacgactc ttgaaaatta ttttctaaat tagcattaac aaaatgtagc gctatgaatg
     3841 cagcttcgtc aattggaagt tcaataccta actctttttt tattatttgt aaagcccttt
     3901 tcccaagttc aaattcttct ttataatatt tcgatatttc ccagcgtagg ggattcgaaa
     3961 taataatccc ttctttataa cgttctatgc tcgaagaaat atgatccgtt aaattaatat
     4021 agataatttc atcaaaatta ttacccaatg ttattttacc taggttaatt attttttcgg
     4081 tgatgtacac caactccaaa ggaacgttaa taaacatctc tgtaaaacgg gtcatattat
     4141 ctctattttt gagaaaaaaa cttttctcaa tatcaattgg atttacttta tctccagttt
     4201 ttcttccaaa agctatgccc cttccaaaaa gaagaatatc gatatctttt ttactttgcg
     4261 caattacggc attgtggttt agtattcgtt ttatgatcat aaaatttccc ttttaaaata
     4321 aaaggaacct acttaaaaac atcaagaaac ttcttccgat gtgattaaat aggttcctgc
     4381 tcacttgtat tagtgataac atccttttat ttcaattttt aatggtgaca tgaagcttaa
     4441 ataattaata actctgtaac cattttcatt ttatgatatt tcaatctatt tgtcaagtac
     4501 ttgtagaaat ttttttattt tgtgtgattc gaatgtgata atggcaacag tctcactaaa
     4561 gaaatgaaaa tcatacatag aaatttttaa aaattttctc tatcgtaaac ctgccactag
     4621 ttcagaaact atactagctg attccaaacg taatatggtc atctcatcta ccttccctaa
     4681 taatggcatt gcaccatacc aaacaatagt cttattcacc aaaagaatag gcgttactat
     4741 ttttgattga gtaaaagaca ctttaatttt ctggctcttc aactggtcta gccatgcttt
     4801 atttgcaacc gtctctggta tacatatctc aatttgacta atcctaaatt cttttagaaa
     4861 attcatcagt tttgtctggt gcacataagg taaaataagc atacattcct gtctttcccc
     4921 tgctaagtcc tctctcaaca ccttctcata tctactatca acataaacga attgtttctc
     4981 ctcaccctca atggcacgat aatccatctt tcgataagct acttgtcgtt tctgaaacat
     5041 cttttctaaa taaggaacat gaatatccac ataatcgaaa atacgcacca aagacttatc
     5101 cttgtagttt ctatgaatcc gacctgcgta ctgaatcaaa ttatttttcc aagaaaaggg
     5161 tgctgccaag ataagcgtgt ccaactgagg taagtcaaaa ccttcgccaa tgtattttcc
     5221 agtaaacaac aaaataaacc ctttatctaa ctgttctaac gtctccagta aactcgttct
     5281 ctttctcgga cgttggtttt tccgctaata atgtaacagt catcaacctc tttctctttc
     5341 aataactttt caaagacatc tatctgttga attcgattaa ctaaaaccaa gatattccgt
     5401 ccttctgcca cttgggctag aatatccttg agaatcaact gattcctcgc tgagtcagta
     5461 gcaatccaat cactaagctg tataaaatta cttgctttgg tcttttcaat ctccaaatga
     5521 ccaaaagaag tgaatcttaa ttgcaattgc cgtttaaaat ccgtttccct cttatcagca
     5581 gtatggagta tctcaccaat tctctgaaaa acaataggct catgaccatt cttacgctca
     5641 ggcgtagccg tcaaaccgta aagatacttc cctctaaact gagcaacaac tttttcaaac
     5701 atcaaggcag agatatgatg acactcatcc acaatcatca tctcatactc atccaaaaga
     5761 ctttgactat tttccaactt aaatagagat tgaatcataa caacatcaac cagtttactc
     5821 agtcatttct tagccccacc gtactgcccg acatagccta ttaccctttc acgacctgat
     5881 ggtgtataac gggtagcttc tgcctcttcg aaagtcaaaa aacactttaa acgatccagt
     5941 cattggtcta agagttgcct attatgaact aggataatgg tttttgtctt acgttcagag
     6001 ataagagcag cacctaaaac gctctttcca aaacctgtcc cgcatgaagt aaaccatttt
     6061 ctttagaatt catatctgac agggctaatt cttgctccaa agtaagctct cccttaaatg
     6121 ctactctaat agacctttgt acctttctcc tatcctccac aactacctgc ttaaatttat
     6181 cttgcaatgg atataacaag cctcttggca gccataaata ataatcggat tctccaaata
     6241 aatacattcg ctcaggaatt tgataggttg gctgtcgcat agcctgcttt aaataaaatt
     6301 cgggattaga aaatgaagcc atatttttca agaaaaacag tgtcttgggt gtcacagacg
     6361 attttttaag ttggatcata ttggataaaa cgaccttcaa ctccttatcc aattcttgct
     6421 tgcctaactc ctcttggatt aacagtgcca ctttagcagt tgaaatcttc tgaattcctt
     6481 gcagatacct ccattggtct ccataaggtt gaaaatgttc atccacaaag accgttcgcc
     6541 cttgatgata agcttctcct tgaaaaggaa aggaaattaa attaccaaat ccacctttag
     6601 gaagaacatc ctgatttgga aacatgcgat caaaagaatc aaaggacagt tgcatacttt
     6661 cctgcatagc caattctaat agtttctttc caaacagacg agcctttcga ctcagaatcg
     6721 cttcctcaaa gaagaaccaa atatggagtc cgtaacccga acgagaaatc tctaaatggg
     6781 cttccatctg gcgttccctg gctattcttc gaatggttaa accagcttct ttccaatctc
     6841 cttcatccaa atccagtacc aaaaaataac agctatcatc taagtgcata ggaaagatac
     6901 cgatagctgc ctccccacga aaatgagatt tcaaaacgga gttcgtcaat gtctggaaac
     6961 tccgtttttc aggtggcaac tgcttccaac cataatcata ggaaggaaaa tactgaattt
     7021 tcccttgttc attgataaaa ttcttagcat aaacatcata acgtccagca aacacggagg
     7081 taaacaattg taatttttct tgcgtcgtca agtgactact ttgaagttgg aacatctcct
     7141 cgaaccgaga gcgttccatc acaaactgac tcttgtcttt aagacgttta tagtggaatg
     7201 aaataagata tgaacaaatt gattaggaaa atcaaattaa tttatagaaa tcttttagca
     7261 gtcatggcgt cctattccag cttcaaaatg ctatacacaa gaaaaactca ctatccccat
     7321 taaaagaaaa aaagacatca agtatttcta ccacaattcc atccaaagac acaaaaacag
     7381 ccataagagt cacctccttg attcctatag gctgattata acaagaatag ctgaaattgt
     7441 acacgaaaat aaaatccgaa tagcactcat tttgtatgcg actaatagtc catctcgctc
     7501 cggaatgtac gaagtaaata gagtttaaac gagcagtcta taaaattcaa aaaacgcatc
     7561 atatcaggtg tacatgaact acaccccaaa agttagacag aaaaaatcta acttttgggg
     7621 tgtttttatt atgaaattaa cttatgatga taaagttcag atctatgaac ttagaaaaca
     7681 aggatatagc ttagagaagc tttcaaataa atttgggata aacaattcta atattaggta
     7741 catgattaaa ttgattgatc gttacggaat agagttcgtc aaaaaaggaa aaaatcgtta
     7801 ctattctcct gatttaaaac aagaaatgat ggataaagcc ttactggaag gttggactaa
     7861 agacagagtt tctcttgaat acggtctccc aagtcgtacg atacttctta actggctagc
     7921 acaatacagg aaaaacgggt atacttttgt tgagaaaaca agagggagag tacctgagag
     7981 cggagaatgc catcctaaaa aagttaagag aactccgatt gaaggaggaa aaagagaaag
     8041 aagaaagaca gaaattgttc aagaattaat gactgagttt tcgtcagatc ttcttctaaa
     8101 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctag acaaaccaga
     8161 taaggaccaa gagcttaaag ctgaaattca atccattttt atcgaacaca agggaaatta
     8221 tgcttatcgc tgtattcatt tagaactaag aaatcgtggt tatctggtaa atcataaaag
     8281 agttcaaggc ttgatgaaag tactcaattt acaagctaaa atgcgacaga aacgaaaata
     8341 aaggagacgt tggtaagaag gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa
     8401 caatggaaaa gtgctacaca gatgtgacag aatttgccat tccagcaagt actcaaaagc
     8461 tttacttatc accagtttta gatggcttta acagcgaaat tatcgcctat aatctttcaa
     8521 cttcacccaa cttagaacaa gtacaaacaa tgttggaaca ggcattcaaa gaaaagcact
     8581 acgagaatac gattctccat agtgaccaag gctggcaata ccgacacgat tcttatcatc
     8641 ggttcctaga gagtaaggga gttcaagcat ccatgtcacg taagggtaac agcccagaca
     8701 atggtatgat ggagtccttc tttgggattt tgaaatcgga aatgttttac ggttatgaga
     8761 agtcgtttca gtcgtttaag caattggaac aagctattat agactatatt gattactaca
     8821 acaataaacg aattaaggta aaactaaaag gacttagcct tgtgcaatac agaactaaat
     8881 ccttcggata aattatttgt ctaacttttt ggggtcagta cacctaaaac tttgatgata
     8941 tacgttttct tgtgagaata tttacttcat ttttgcctaa aattcaatgt ttactcagta
     9001 tttggattat gaaaaatcga ggtctaaatc tagatacatt ttttctgaag acaaatcatt
     9061 ttgaccaccg agcaagagat tttcaaaaaa agctgttaaa aactcagaac gtcgctgtaa
     9121 aatctttgca ttatctaata ccaaggcatc acgaaaatat ttggaatgtt gctgaaatgg
     9181 tgtattatca atatcaaaac caaactcacg aagatactga atcaaaaaga ccgttactgt
     9241 ccgagtgttt ccttcgcgaa atggatgaat ctgccagatt cctgaaataa aatgctggat
     9301 ttgtttaacc acatccgcct gagttagtgt cgcatatgca acttgttttt cctgattaaa
     9361 atcataatct aaggtcattt gaatcatgga gtaatcagag tacacaacac tttcaccatt
     9421 caaaacaggt tcattctttg tgatattggt ctgacgaaat tgccccaccg gaatagaggg
     9481 ttcaaatata tcttgaaaca actccttatg aatagcaagt aaggtcgcag gactaaagct
     9541 aaagcctctt cgagacaata gttctacaat acgtagagaa accaagtctg cctcttccgt
     9601 acttgcatca atagtatggt gataagccgt tgcatcctca taaacctgct cataagtcag
     9661 ttctccccgg gactgtttct cagccaaaga ttccatatac gctgatggca ctagattgtc
     9721 aactttctgc agaccaaaac ctatccgcca taaatcacgc ttcgcttcat aagacaagtt
     9781 tggattgtca atgttgtaag ttggttgcat agaaatatcc tttcaattgt ttttcttcat
     9841 taccagtaaa tcacgaaatt ggttggaaac tggcttaaac tataaaaagt cctcacaata
     9901 g
//
LOCUS       DAVLHB010000062         9834 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLHB010000062 DAVLHB010000000
VERSION     DAVLHB010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.062"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(41..175)
                     /locus_tag="VXE36_001860"
     CDS             complement(41..175)
                     /locus_tag="VXE36_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0780102.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     "
     gene            453..548
                     /locus_tag="VXE36_001861"
                     /pseudo
     CDS             453..548
                     /locus_tag="VXE36_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(801..1421)
                     /locus_tag="VXE36_001862"
     CDS             complement(801..1421)
                     /locus_tag="VXE36_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0780103.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1421..1903)
                     /locus_tag="VXE36_001863"
     CDS             complement(1421..1903)
                     /locus_tag="VXE36_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0780104.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1903..2745)
                     /locus_tag="VXE36_001864"
     CDS             complement(1903..2745)
                     /locus_tag="VXE36_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0780105.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2840..3628)
                     /locus_tag="VXE36_001865"
     CDS             complement(2840..3628)
                     /locus_tag="VXE36_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0780106.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3772..5151
                     /gene="glmU"
                     /locus_tag="VXE36_001866"
     CDS             3772..5151
                     /gene="glmU"
                     /locus_tag="VXE36_001866"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0780107.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            5161..5706
                     /locus_tag="VXE36_001867"
     CDS             5161..5706
                     /locus_tag="VXE36_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0780108.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5718..6032
                     /locus_tag="VXE36_001868"
     CDS             5718..6032
                     /locus_tag="VXE36_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0780109.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            6049..6741
                     /locus_tag="VXE36_001869"
     CDS             6049..6741
                     /locus_tag="VXE36_001869"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0780110.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            6818..7309
                     /gene="rocS"
                     /locus_tag="VXE36_001870"
     CDS             6818..7309
                     /gene="rocS"
                     /locus_tag="VXE36_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0780111.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7407..7997
                     /locus_tag="VXE36_001871"
     CDS             7407..7997
                     /locus_tag="VXE36_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0780112.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVATFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            8006..9769
                     /locus_tag="VXE36_001872"
     CDS             8006..9769
                     /locus_tag="VXE36_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0780113.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3037 a         1719 c         2090 g         2988 t
ORIGIN      
        1 cgtattctcg tagtgcttct ctttgaatgc tgttccaaca ttaacgatca atcaatttaa
       61 tcatgtacct aagattagaa ttgtttatcc caaatttatt tgaaagcttc tctaagctat
      121 atccttgttt tctaagttca tagatctgaa ctttatcatc ataagttaat ttcataataa
      181 aaacacccca aaagttagat tttttctgtc taacttttgg ggtgtagttc atgtacacct
      241 gatatgatgc gttttataat tttaaagact ttttgaccag cctcattttt taacttgata
      301 ctcagtgaaa agcaaagatt aaactaggaa gctagctgta ggctgctcaa agaacagctt
      361 tgaggttgca gataaaactt gtgaggtaac caacatatat aatgtgaagc tgacgtggtt
      421 tgaatagatt ttagaagggt atgagtctgg aagttttaat ggataatgca agattccata
      481 gaatgggtaa gctagagttc ttatgtgaag agtttgggca taaactttta ccttttcctc
      541 cctactcatc ttagtataga aaagtgaatc taaaatagta cataactgct tctaaaacat
      601 tcttataaat tgatttaaat tctcaaatca tattattcag ttcttatttc attttgctct
      661 acaatcctgt tgagaagaca cgtgttcata tcaaaaaggt attggcaagt tgcaatacct
      721 ttttacaagg ttcttttgtc ttatttttgt ttcaactgac tatatctcct atggttctag
      781 ttcagaaggc taggctataa ttatgattga taagaagtat cattccaagt attgagagtg
      841 aatgtttcaa aatcatgggt ttctataatg gtcaggctgg catttgctag accgccatct
      901 ttacgaagaa gtggttcttt atagcctagg agagtacgaa gactggcagt aagattggcg
      961 ccgtgtccga caattagaat acgctcagct ggactatctt ttaatgattt gataaattgg
     1021 atggtccgct gagttgtact atagagggat tcggctccga acattcgagt gtcaaattga
     1081 gcaagatttg aacgaaaagc ctggatttgt tgcgggtaaa tagcttccag ggttgcaatt
     1141 ttcaaacctt ctaacttccc aagttgccat tcacggagat taggaacgat ttctaaagaa
     1201 cagggggtat ggagttgact ttggataatc tcagcagatt tgaccgctcg aggtaaatca
     1261 cttgaataaa tctgatcaaa aggaatttcc ttgagatact ggccaagtcg ttttagggtt
     1321 tcaatggatc caggaagaag aggagaatca ccgctagcac cttgaaaacg accttcttgg
     1381 ttccagaggg tacgaccgtg gcggacaaag tagagtttca ttacttgatg tcctccaaaa
     1441 tatctacaaa gtctgccttt acaaagctag ccaagtcttg tggcgcgacg ataatgctgt
     1501 gtccgacttc gcctgcagag acaatcattc gatccaaatc tagagcaatt ttatcgataa
     1561 aaatgtgata attgtgtttc tgacgaattc cgacaggatt attggctcca tgaatgtaac
     1621 cagttgtttt ttctaagtcc ttttgtggaa tcatgctcac ttttttattg ccagaaattt
     1681 tagctagttt cttttcagac aagtgctgag tgatagggac aattccgata atcggtccgg
     1741 tcttgtctcc caaaagcgcc aaggttttga aaatctgatc tcgttcataa ccttgaggaa
     1801 gctctccttc tagggcattg atttgaatcc cctgatgagg gatagctgct ttagatagga
     1861 tttgttccac caatgttttt ttgattttaa ctttttttgc cattatttat atttatcctc
     1921 caattgactc atccaaatac caagccagat tcccagcgca aagaagaagg cgatgatgac
     1981 ataaccgaca agtgaaagtc ctgtgtattg gatactttca gcgtttcctg catttggaat
     2041 taagatcaaa agggtacttg ataggacgat accgatgatg aaatgataga cgcgtgagtg
     2101 gtagttgttt aaggcataat ccatcaattt tgaaaaaacg atgagagttg cacctgcacc
     2161 aattccaatc ggaaagaagg ttcccaagag atcaaaagtt ttaaaaccag tcaacatagg
     2221 agcatagagt cccaaaatca aaagtaagtt cgatgggctg aggccaggaa ccaagacgcc
     2281 aagggccaat agtgcgcctg ctaggacgaa gttaagaaag ctggcgctta aggttccaac
     2341 gacaaaattt aaggcataga gtcctaatcc agaaatgata aaggttgtcc ataaccaagc
     2401 taaatcaatc ttgtctcggt cagattctcg agttgattct ttgaggaggc taggaactgt
     2461 accgataata gctcccgcaa agctccataa tacaaagacc tgataatttt caagcaggta
     2521 ttcaatcggg taggaaaata agccgattcc cagaagcata ccgatggcaa ctggaataaa
     2581 gtacaaaaca ttttctttaa ggtctttaaa gggatgggcc agaaagccaa tcattcgttc
     2641 atagattcct aagattgctg ctagaacccc tccggaaatt cccggtagga taaatccaag
     2701 agcaattaca atccctttaa taacgcgtgc taaccatgag agcatatatt tcctccaact
     2761 atttctattt caaaaaatcc ttactatatt gtatcacaat cagacacaaa aagaaaaagc
     2821 aaatgataaa caaatgcttt taaggtttta aaaaaagttt tcgaaaggtt tcttctttat
     2881 tttttaaggg agagataacg ttgatatcta aatcgtggtc aaagccggca atttttcctt
     2941 tagatgtgta ttggtgaata tcataatcta aatcagtttt aggactgctc tccaaaaatc
     3001 ctgagtctga gccgtaggac ggaatccaaa cagaggtaaa cttgcctgta tcaatactgt
     3061 gttcttccat gaagtagaca ccaacgtaga tgccgatgtt tttagcacct agtgatgcta
     3121 gttttgctcg aaagttttcg acaccttcgt tcatattaga catggttttg tcttccacgt
     3181 caagccaata gtaactaggg ctgtaaggag aggcagcatt gtagaaaact tcggcagcct
     3241 tttccatttc ttggacactt tttccagcta cataagcgta gacagcaact gggacattcc
     3301 gcttttgaag ttcagtgata tgactcttat aggccttgtc tattccattg ataaatgaag
     3361 catcattttc ttttgttgtt tgagcaccac tgtgaacacg aacaatagca cctgaaatat
     3421 tttgtgagag ggcatcgtag ttgatttcct caggacgctg ccagccagag aggtcaataa
     3481 tcggtttgtc taagtgtttc aaagcctgtg ctatattgga ttttgtttta aacgattggc
     3541 tgtcattaag tgggcgattg atgattaaaa tgaacatcat aatcccaaaa aaactaaata
     3601 aaataagtgg atgaatttgt tttctcatat cttataagtc taccctaaaa atcaaaaaaa
     3661 atcaaaaaaa tgggttaagg aagagacttt agagcatttt ttcattcaag agtgcggaat
     3721 gatttgaaat atggtataat aaaagggaat ttctacagaa aagagaagat tatgtcaaat
     3781 tttgccatta ttttagcagc gggtaaaggg actcgcatga aatctgattt gccaaaagtt
     3841 ttgcacaagg ttgcgggtat ttctatgttg gaacatgttt tccgtagtgt gggagctatc
     3901 caacctgaaa agacagtaac agttgtagga cacaaggcag aattggttga ggaggtcttg
     3961 gctggacaga cagaatttgt gactcaatct gaacagttgg gaaccggtca tgcagttatg
     4021 atgacagagc ctatcttaga aggtttgtca ggacacacct tggtcattgc aggagatact
     4081 cctttaatca ctggtgaaag cttgaaaaac ttgattgatt tccatatcaa tcataaaaat
     4141 gtggccacta tcttgactgc tgaaacggac aatccttttg gctatggacg aattgttcgt
     4201 aatgacaatg ctgaggttct tcgtattgtt gagcagaagg atgctacaga ttttgaaaag
     4261 caaatcaagg aaatcaacac tggaacatac gtctttgaca acgagcgttt gtttgaggct
     4321 ttgaaaaata tcaataccaa taacgctcaa ggcgaatact atattacaga cgtcattggt
     4381 attttccgtg aaactggtga aaaagttggc gcttatactt tgaaagattt tgatgaaagt
     4441 cttggggtaa atgaccgtgt ggcgcttgcg acagctgagt cagttatgcg tcgtcgcatc
     4501 aatcataaac acatggtcaa cggtgttagc tttgtcaatc cagaagcaac ttatatcgat
     4561 attgatgttg agattgcttc ggaagttcaa atcgaagcca atgttacctt gaaagggcaa
     4621 acgaaaattg gtgctgagac tgttttgaca aacggtactt atgtagtgga cagcactatc
     4681 ggagcaggag cggtcattac caattctatg attgaggaaa gtagtgttgc agacggtgtg
     4741 acagtcggtc cttatgctca cattcgtcca aattcaagtc tgggtgccca agttcatatt
     4801 ggtaactttg ttgaggtgaa aggatcttca atcggtgaga ataccaaggc tggtcatttg
     4861 acttatatcg gaaactgtga agtgggaagc aacgttaatt tcggtgctgg aactattaca
     4921 gtcaactatg acggcaaaaa caaatacaag acagtcattg gagacaatgt ctttgttggt
     4981 tcaaattcaa ccattattgc accagtagaa cttggtgaca attccctcgt tggtgctggt
     5041 tcaactatta ctaaagacgt gccagcagat gctattgcta ttggtcgcgg tcgtcagatc
     5101 aataaagacg aatatgcaac acgtcttcct catcatccta agaaccagta ggagcctatc
     5161 atggagtttg aagaaaaaac gcttagccga aaagaaatct atcaaggacc aatatttaaa
     5221 ctggtccaag atcaggttga attaccagaa ggcaagggaa ctgcccaacg ggatttgatt
     5281 ttccacaatg gggctgtctg tgttttagca gtaacggatg aacaaaaact tatcttggtc
     5341 aagcagtacc gcaaagctat cgaggctgtc tcttacgaaa ttccagccgg aaaattggaa
     5401 gtaggagaaa acacagcccc tgtggcagct gcccttcgtg aattagagga agaaacagcc
     5461 tatacaggga aattagaact cttgtacgat ttttattcag ctattggctt ttgtaatgag
     5521 aagttaaaac tatatttagc aagcgatttg acaaaagtgg aaaatccgcg tccgcaggat
     5581 gaggatgaaa ccttggaagt ccttgaagtg agcttagaag aagcgaaaga attaatccaa
     5641 tcaggtcata tctgtgatgc caagacaatt atggctgttc agtattggga gttgcagaaa
     5701 aaatagagga ggtcagtatg ggtaaatctt tattaacgga tgaaatgatt gaaagagcta
     5761 atagaggcga aaaaatttca ggtcctcctt tgctagatga taatgaggaa actaagattt
     5821 taccaacctc ttcttcccgt tttggttatg ccaatcctaa ggatcatggt tttagccagg
     5881 aaaccttgaa gattcaggtc gaaccatcta ttcataaaag ccgtcgcatt gaaaatacca
     5941 agagaaatgt cttcaattct aagttgaata aaatcttatt cgcggtcatc tttctcttga
     6001 ttttgcttgt tttagcaatg aaacttttgt aatagaaaag gaattgaaat gaaaatagga
     6061 attattgctg ctatgccaga agaactggct tatctggtcc agcatttaga caatgcccag
     6121 gagcaagttg ttttggggaa tacctatcat acaggaacca ttgcttctca tgaagtcgtt
     6181 cttgtagaaa gtggaattgg taaggtcatg tctgctatga gtgtggcgat tttggctgat
     6241 catttccagg tggatgccct tattaatacg ggttcagctg gggcagtagc agaaggtatc
     6301 gctgttgggg atgtcgtgat tgctgacaaa ttagcctatc atgacgtgga tgtcacagct
     6361 tttggctatg cttatggaca aatggcgcaa caaccgcttt atttcgaatc agacaaaacc
     6421 tttgttgctc aaatccaaga gagtttatct caattggacc aaaactggca tcttggtttg
     6481 attgctacag gagatagttt tgttgcagga aatgacaaga tagaagcgat taagtcccat
     6541 ttcccagaag ttttagccgt ggagatggag ggggcagcta ttgctcaagc agcgcatgcc
     6601 ctcaatctcc cagtcttagt catcagagct atgagtgaca atgccaacca tgaagcaaac
     6661 atcttttttg atgagtttat tatcgaagct ggacgtcgct ctgcccaagt cttgttggcc
     6721 tttttgaagg ctttagatta agcggaaatt tgacagtttt tctagcttat gataagattt
     6781 aagtaaagaa aagctagaaa acgtttcaga ggatattatg agtattgaaa tgaccgtcag
     6841 tgagattgca gaggtcttag gattatctcg ccaagcaatc aataaccgtg tcaaagaatt
     6901 accagaagaa gacacagata aaaatgacaa aggggtaaca gttgttacca gaagtggctt
     6961 gattaagcta gaagaaatct ataaaaaaac gatttttgaa gatgagcctg tcagtgaaga
     7021 tgtcaaacaa cgtgaactga tggagattct agtggatgag aagaatgcag aaattcttcg
     7081 tctttatgaa caattaaaag ccaaggatcg tcagttatca gaaaaagacg agcagatgcg
     7141 tatcaaagac cgtcagattg ctgagaaaga caaacaatta gatcagcaac aacaattgac
     7201 ccttcaagcc atgaaggatc aagaaaatct taagctagag ctggaccaag caaaagaaga
     7261 agtccaatcc actaagaaag gcttttttgc tcgtttattt ggaggataat caaggagctg
     7321 tttaggttaa atgctaacct gatggcttct tttgtttgtg aatagtatag ttgattagaa
     7381 cagagacagt agaggagagg tacagaatgg aacgattaga agattacatt gcttttgatt
     7441 tagaatttaa tcagcacgaa ggacaaacac acttgattca agtatcggca gtgcgtttta
     7501 gagatggtcg ggaaatcgat gcctatgatt cctatgttca taccagcgtc cctctaaaaa
     7561 gctttatcaa tggtttgacc gggattacag ctgagacctt aaaagatgct cctccagttg
     7621 agaaagtctt agaagaattc caagagtttg tgggttcttt gctgatgata ggctacaatg
     7681 ctgctaaaag tgatttacct attttagcag agcatggttt agactatagc caacagtaca
     7741 aggtggattt gtatgatgaa gcttttgaac gtcggagttc agatttacat ggtattgcca
     7801 atctcaaatt gcaaactgtt gccacatttc ttggatttca aggtcagtct cataatagtt
     7861 tagaggatgc tcggatgacg gcgcgtgttt acgaatcctt cttagagtcg gatcaagcta
     7921 gggaattgtt agagacagaa agtagcttat caaacaatcc ttttggtggc ttggacttgt
     7981 ctcaattatt tgactaggag tgcctatgaa acctgaaaaa cctaaaaaat tgggtcttaa
     8041 acagatttac ctcaatcttg ataaaatcct ctttctattt ttcttgattt ttatgatagt
     8101 ggagtatttg tgggtaccat tcaattcatg gttggctagc ttcttattag atcagacagg
     8161 ttatcttttt atttcctata acaatgtctt agccatcctt actcattctc cattgattag
     8221 tctagctttt ttagccttga ttgtaattaa ccttctggtt gcttattttc aaataggact
     8281 cctctttatt ggtgctcgtc atctcctcta taatgaaaag cgaaggctaa ttgagtatat
     8341 ccgcaaggtt ttccatgaaa gttttggatt tatgaaaaag ctaacttgcg ctaaagcctt
     8401 gtttatcttt ttctatatag ctatgctgtt tccttttata cggaaaatgc tgaagattta
     8461 ttatcttaat aaaatcgtca ttccagagtt tatccaagct tatttagaag atagatattg
     8521 gatgtggtgg ctgagcatcc tacttctatc tcttatcttt ctctatgtct ctgtcagatt
     8581 gatgtttgcc cttccgaaga ttgtatatga tcagctgact gttcgagaag cagtgatgtt
     8641 tagcttggag aaaaccaaga agagagttac tttttatgct tggaatttat tttacatctt
     8701 gctcaaagca catttattat tttatcttcc tttgatccct ttattattgg ctcaaacttt
     8761 ggtagatgat atcactcaga gagagtctct gattcttggt attttgaatt ttgtcgtgat
     8821 taaaaatctc tattatatgg ctctgactta ttttttggtt aaatttgttt catttttgac
     8881 aggaaaggag ctggatatgc ttcctaggag agaaaaagat cacatcgtgc gatggggtgt
     8941 catgacttgt gccagtcttt tctttgcctt agaaggttat atttatctgg aggctcccat
     9001 ggttcatcta cctcaactta tttctcaccg aggggtttcc aatgcaaatg ggattcaaaa
     9061 tacagtagag tccttggaaa ctacagcaca actcaaacca gacttggtgg agacggacgt
     9121 gcaggaaaca aaagatgggc agtttgtcat gatgcatgat gctaacttga aaaatctagc
     9181 aggtatcaat aaaagtcctc aagacttaaa cttggaggag cttaaaggga ttgatatttt
     9241 tgaaaatggc taccagacta aaatttcaag ctttgaagat tatctcagtc gagccaacga
     9301 acttggtcaa aaattactaa ttgaaattaa aaccagtaaa aaagatagtc cagacatgat
     9361 gaaccgcttt ttagcccgtt atgctgcaaa gctcaagatt tatggacatc aaatccagtc
     9421 tttagactac catgttgtcg aaaaagtaag acagtatgat gccgaactgc cagtttattt
     9481 catcatgccc tacaattctg tctttcctaa aacaagagcg acaggatata ctatggagta
     9541 ctcaaccttg gatgaatatt ttgtaagcaa actatggaca acggatcaga aactttatgt
     9601 ctggactgtc aatgattcag aagctatcag caaatctctt cacttaggag tagatggagt
     9661 gattacagat gatttggaaa aagttcagcg ggaaatagaa gtagcccaag aagatccaga
     9721 atatacggat ttgctcttga aaaaagcatt ggaattcttt gaattttagt aataaaaaag
     9781 aggaacggtt gttcctccca tgataggtaa gtattcttgt gaatgcttgc tttt
//
LOCUS       DAVLHB010000063         9818 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLHB010000063 DAVLHB010000000
VERSION     DAVLHB010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.063"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..169
                     /locus_tag="VXE36_001873"
     CDS             <1..169
                     /locus_tag="VXE36_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0780114.1"
                     /translation="KEVAFYLTSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTP
                     DWNYMERYRDR"
     gene            135..461
                     /locus_tag="VXE36_001874"
     CDS             135..461
                     /locus_tag="VXE36_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780115.1"
                     /translation="MGITWKDIEIDKEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEY
                     KNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNY
                     DVGESL"
     gene            1145..1306
                     /locus_tag="VXE36_001875"
     CDS             1145..1306
                     /locus_tag="VXE36_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780116.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1398..3077
                     /locus_tag="VXE36_001876"
     CDS             1398..3077
                     /locus_tag="VXE36_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0780117.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3345..3911
                     /locus_tag="VXE36_001877"
     CDS             3345..3911
                     /locus_tag="VXE36_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780118.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4233..4421
                     /locus_tag="VXE36_001878"
     CDS             4233..4421
                     /locus_tag="VXE36_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0780119.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4483..5241
                     /locus_tag="VXE36_001879"
     CDS             4483..5241
                     /locus_tag="VXE36_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0780120.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNISDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            5299..6153
                     /locus_tag="VXE36_001880"
     CDS             5299..6153
                     /locus_tag="VXE36_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0780121.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6265..7149
                     /locus_tag="VXE36_001881"
     CDS             6265..7149
                     /locus_tag="VXE36_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0780122.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDDYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7312..8085
                     /locus_tag="VXE36_001882"
     CDS             7312..8085
                     /locus_tag="VXE36_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0780123.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESASNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNYIGSQSLQ"
     gene            8152..8973
                     /locus_tag="VXE36_001883"
     CDS             8152..8973
                     /locus_tag="VXE36_001883"
                     /inference="COORDINATES: protein motif:HMM:NF012356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780124.1"
                     /translation="MTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYW
                     IEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAV
                     MNYPLSDSIKDYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTA
                     NEDVQLVKSALSFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFM
                     KRLIKIRKYASVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEK"
     gene            9326..9781
                     /locus_tag="VXE36_001884"
     CDS             9326..9781
                     /locus_tag="VXE36_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780125.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         3522 a         1352 c         2049 g         2895 t
ORIGIN      
        1 taaagaagta gcattctatt taacttcaat tattaggcaa gctttaaaaa atactgaata
       61 taaagatcaa atatctagca cagtattgcc agatatcaaa attaaattac cgatagacag
      121 tagaggtact ccagattgga attacatgga aagatataga gatagataaa gagatagata
      181 aagagagaga gggagagata gataaaaagt ccacccccat tttttatgga gaattcaaaa
      241 atgtaaggtt aagcaaagaa gaatataaaa atctaaaaga aaaattaaac tcacacacag
      301 atataatgat aaataaacta tccagataca tggaaagcag tggtaagacc tatcaaaacc
      361 actatgtgac aatcttaaaa tggtatgaag aagataaaga caaactaaga cagaaaggtt
      421 taaataaaaa aatgaattat gatgtaggag aatctttata gataaaaaga ggtggaaagg
      481 cactattaaa gactttaagt ctaaaaaggt atcaaagtat gccagagata aaaaaatata
      541 aatataacac tttaaaggcg attagaaaat taaagaaatg ctagaagact tttagatgac
      601 agttaccaag agggtctaat tttcactgct acttatgcag tgggaatttg acctttttat
      661 ataagcaaat tctatttcaa aattggttac caagaaagac ttcttttcac tgttaagtat
      721 aagagggtaa tttatagaat tttgttacat taagataaat attttctgat ggtcaaattt
      781 taaaaagatt aataactctc gataaatttt gaaccttaac aattgaatag accaagacaa
      841 gacgttaatt atttttggag cgtaataacc tatccgtcaa gatctttcgg ctgaataatt
      901 cggcaaaaaa agttctgcta agtaaaaaga aagtgagcga taagtaagag tttgaatata
      961 gggagggata ccctatccgc tatgaagaaa atgaggataa tgatacttct aaggttgaag
     1021 ccggctcatc cggaatagag gcggaggtga gattcctatg ttgctaatcc aaagcacttg
     1081 tcaatgtcaa aaaacttaat taaacaaata attattagat ataaaacttt agaggaggta
     1141 tatattggac aatgactgga atggattggc tgatttaata gcaaatctga ttgcaaaata
     1201 tgctggtgct ttagatttag ataatctacc cgatccaacg ccagcaaaaa atcaagagat
     1261 gaaaaatagt tttgacatgg caaaaacaca aattgagacg gactaataaa agtgttataa
     1321 tatacttgaa atgatagtcc aaacttaaat taaaaaaatt atatatgata tagaaaaatt
     1381 atattgaggt taatactatg tcaaaagaaa aaataaaagt atacctctat acacgagtat
     1441 ctacgtcaat acagatagag gggtattcgt taggggcaca aaaatcacga atgaaagctt
     1501 ttgctattta caacgattat gaaattgttg gagagtatga agatgccggg aagtctggca
     1561 agtctattga aggtagaata cagttcaatc gaatgatgga agatataaaa tctggaaaag
     1621 atggagtatc ttttgttctt gtgtttaagt tatcaagatt tgcaagaaat gccgctgatg
     1681 ttctttctac acttcagata atgcaggatt atggagttaa tcttatctgc gttgaagatg
     1741 gcattgattc atctaaagat gctgggaaac taatgatttc tgttttatca gctgtggctg
     1801 aaatagaaag agaaaacatc cgtattcaaa caatggaagg ttgcattcaa aaagcaaggg
     1861 aaggaaaatg gaatggtggc tttgctccgt atggatataa acttgaagac ggcaagctgt
     1921 ttataaatga ggaagaggca gttgcaataa gaacgatttt cgaccagtat gtaaatacta
     1981 cgataggagc caatgggata tctaaatact tagagaatca tggaattaga aaaatcccaa
     2041 gacagaatgg taagaatcct ttgtttgatg caggtcttat aagaaagata ttaaagaatc
     2101 ctgtatataa tgggaaaata gcatttggaa gaagaacttt agaaaaagtt catggtacaa
     2161 gaaatgaata taagcaggtt gaacaagatg aatatctaat atctgaaggg atacatgaag
     2221 ctatagtttc cgatgaagtt tggcaagctg ctcaggttaa gctaaaatct caagcaaaga
     2281 aatatgagca tgtgaataaa ggaaaagata cacgcacaca cttgctttct ggaattgtaa
     2341 aatgcccgat atgtggagtg ggaatgtttg ggaacaagtg tatcaagaaa aagaaagatg
     2401 gcacaaagta taaagatttt tattactatg gttataaaca taggcagatg ataagaggtc
     2461 ataagtgtac attcagtaag caaattagag aagaattgtt agatgatgct gttgcagagg
     2521 tgattgtcaa gatagtaagt aatccgaaat ttgcttctat gatgcaagaa aaaatcaaca
     2581 tgaaggtgga tacctctgaa atagaaaaag aaatagataa ttaccaaaag gaattgagaa
     2641 agagtcattc tacaaagttt aagctaattg aggaaataga taatttagat gttgaagata
     2701 agcattataa gagaaggaaa caggatttag atgatagact atatcgtatg tatgacaaaa
     2761 tagatgaatt agaatcatca ctaattgatg cgaaagcaaa gaaacagact attgaagctg
     2821 aaaagcttac aggagataac atatataagg ttctgatcta ttttgataag ctctataaag
     2881 tcatgaatga tgtagagcgt aggcagttaa tttcagcttt gatttctgaa attcaagttt
     2941 atgaagaaaa acaatctaac ggacaatggc taaaatccat tacttttaag ctaccaatta
     3001 tagaagaaaa tctcaacata gatttggaca atgatgaaca agttgaatgt gtaagtttat
     3061 tagagaaacg tagttaatcc tcaaaaggtt ccccaaactt tttgagtccc actgacgcat
     3121 cacgctgagg cggtatcact gcttgtacga gttgaagcat cagcgaagta aaagtagatg
     3181 ttcagccaat gcgacgaggt gagaccgaag gtcgataagg tgtgttctgg gtataggact
     3241 cgtaaagtaa gtaggaaata tgatgagatg atacagagag cctgaattgg tcaggtgacg
     3301 tgcttattta cattagcctg ataatgaaaa tggagagatt atcgatggtt atattggaat
     3361 tgtaccaaaa tgattattct aaagatttag tagcatttga ttccatagaa gatgggaaag
     3421 cctttgtggc tcaaatcccg ggatacactc tggaaacaga agatggtttt gaagtggagt
     3481 attttaatcc taaaaacata ccggattata tggaaattat ttttaacgga aatattgttc
     3541 ctttatctaa atttatgttc gatcctgagg aaaatgtaaa cattatttgg aaagagattt
     3601 caaatttatc cctcaaaaat gatagagtga tcgaaggata ttcaaaaatt gatgcatatg
     3661 tcgttaacaa ccatgaagtt aaagcctatg tcgaaacaag agaaacgaac tatcgtaaag
     3721 caaaagactt cttagaaagc cgcggatatg aaatcgacag aagctttttc ggaagtgaag
     3781 acggtgaagc gattctttac agaaaaaaag ggatcgaagt ttggcatttc ttgtgtcact
     3841 tagacccaat gtttgtagag attgaagatg tagaaggata tgttaaagaa gaagttggag
     3901 agattcaata gtcaaccaaa gttccttgtg agtatatacc tttgctagta aaagagtcaa
     3961 aacgttataa cgaagggggg gaagaaaacc cttgagtgta agtctttttc ttgtttagag
     4021 ggaaagtatt agagtagccg ctcataattt atactagatt tgataactga tttgagacag
     4081 attttatttc tataaatatt gtgaaaattt tttaatacca aagatttaaa gttactgtgt
     4141 taaaaatcct ctccactttt aaactaatgt attataaaag ccagttgaca caagtgtgac
     4201 acttgtgata gaattaactt gaggtgatga aaatggcaac cgataaaaat agaataatga
     4261 ttagcttgga tgataaaaat ctagagaaac ttgaaaattt agtagaagat gctagagata
     4321 gaaggggaat gcgactaaca aagtcccagg ttattgaatt actcctaaat accgttgatt
     4381 atttcgatga tattatgggg gctatttact caaaaaaata agagcaaaat tgctattatt
     4441 ttttacaaat tggtgtaaca ctagtgatat aggagtgatg aaatggttgt ttatattaga
     4501 caaagtaaat taccaagtga ggtttcaatt aataaataca atgctcaagt aggtgcctac
     4561 ttacaaggag aagaagttat tttatatcaa tctttttctg aaataaaaga gttaacaagt
     4621 gaagatatag ttgtagatta tataatggag actagagcat tactaaaaat gatgggctta
     4681 aacgttccgg tttatgacta tcctattgag cttaaagagt tttatggtcg aaagatttat
     4741 gctggtattt taggagagat tgtgaatata tctgataatt ggggaaaatt tattaagcct
     4801 aaagctggtt caaaagtctt tactggaaga gttgttaatg gaacccatga tttaataggt
     4861 attggtctac ctttcgacta tcctatatgg attagtgagg ttgtagaatt catagctgaa
     4921 tggcgttgtt ttgtgttaga tggtcgcgta ttagatgttc gaccctatac aggtgattat
     4981 catgcacaat ttgatgcaag tgtaattgat gaagcgatat catgttggaa agatgcgcca
     5041 atagcttatg gactagatat cggtgttact cgcgatggca gaacacttgt tgttgaagta
     5101 aatgatggtt atgcattggg aaattatggc ctatctcctt taaaatcaat caattttcat
     5161 agagctaggt ggaaagaaat ggtaaaaccc tattttgaaa aaaatgaaat ttttaaaatc
     5221 caacaggatg ttattttcta aaataaatat ggtagataac caatataaaa agcatcaaaa
     5281 tgaacaagga ggaatctgat gcttggagca attattggag atattgtcgg ttctgtttac
     5341 gaatggaaca atatcaaaac aaaggacttt cctttatttc ggaaggactg cttttttaca
     5401 gatgacacgg ttatgacctg tgctgttgca gaagcaatta tgaatggtgg acaaaaagac
     5461 gatttcattg acgcgatgaa gaaatatggc agaatgtatc cgaatgctga ttacggtgct
     5521 cggtttaatg catggctaaa cagcgataac cgtgagcctt ataatagctt tgggaatgga
     5581 tcagctatgc gtatttctcc atgtgcttgg atcatggact gtggttttta tgcgaaaact
     5641 ggtatgtggc catcatctag aggacttacg agtctttctg cagaggtaac tcataatcat
     5701 ccagaaggtg tcaaaggcgc tatggctaca gctgatgcta tctttctatg tcgtttttac
     5761 tttggtggtt attgtagaga gtacgagcaa tcaattaacg acaatcctac agagtgtaaa
     5821 agacgaatta aggattatat agaaaaagaa tacgattaca atctatctca aactttagat
     5881 gaaatccgtc ctaactatcg ttttaacgaa acatgtcagg aaactgtccc tcaagccatt
     5941 atcgcctttc ttgaaagtag agacttcgaa gatgcgataa gaaatgccat ctcacttggt
     6001 ggcgacagtg atactctcgc agcaatcact tgtagcatag cagaggcagc ttacggtatt
     6061 cctgattgga tcaaggataa ggcctattct tacttggatg aacccttaaa ggatgtagtt
     6121 aggcgatggg aaaatagaat aaaagcgtat taatctccag tacgtcagat ttctcttttc
     6181 tgtattttca ttgtataata ggattacatt tacttgcata cgacgaaatg taaacatttc
     6241 tgtttaaaat taaggataaa atcaatgaaa aaagcaatgg taattatcaa ccctacttct
     6301 ggtggcgaga aggctttgga ttacaaagaa aagctggaga ataaagcaaa agaatacttt
     6361 gaatatgttg aaaccaaaat taccgaaaaa gcgctggatg caacacattt tgctgaagaa
     6421 gcttctcgtg agcagtatga tgcagtggtt gtgtttggtg gagatggaac tgtcaatgaa
     6481 gtcatttcag gtattgatga gagagactac attcctaagt tagggattat cccaggcggt
     6541 acgggtaacc tcattacaaa acttttggaa atcaatcaag acatcgatgg cgcaattgac
     6601 gaactggatt ttgatttaac caataagatt gatatcggta aagcaaatga caactatttt
     6661 ggttatatct ttagtatcgg ttctctgcct gaggcgattc acaatgttga aatagaggac
     6721 aaaacaaaat tcggtatttt aacctatgct gtaaatacca tgaagtctgt catgacagat
     6781 caggtcttta acattaaggt tgagacagaa aatggaaatt atgttggtga agctagccat
     6841 gttttggtcc ttttgacaaa ttacttcgct gataagaaaa tctttgaaga aaacaaggac
     6901 gactatgcca acattttgat tctgaaagat gcctctatat tctccaaatt atccgtcatt
     6961 cctgatttat taaaagggga tgttgtcgca aatgataata tcgagtatat caaagcgcgt
     7021 aatattaaaa tctcttcaga tagtgaattg gagtcagatg ttgacggaga taaatcagat
     7081 aacctacctg tagaaatcaa agtcctagct cagcgagtag aagtattttc aaaaccgaaa
     7141 gaggattagt atatagagaa agcctttttt aaggcttttt gtatacttta aaagatagtt
     7201 cctttaacaa cggacattcc ttgcaaatag tttacaaaaa tagtatactg gattcattga
     7261 gtttgaaaac gtttgcgtaa aatttgaatg aatactttag gagacaaatt gatggaattg
     7321 agtgctattt accataggcc tgagtcggag tatgcctatc tttataagga taagaaactc
     7381 catattcgaa ttcgaactaa gaaaggggac attgaaagca taaacttgca ctatggggac
     7441 ccttttatct ttatggagga gttttatcag gatacaaaag aaatggtcaa gataacttct
     7501 ggtaccttat ttgaccattg gcaggttgaa gtgtcagttg actttgcacg tatccagtat
     7561 ctctttgagc tcagagatac agaaggtcaa aatattttgt atggcgataa agggtgtgtg
     7621 gaaaattctc tagaaaatct tcatgcaatt gggaatggat ttaagttgcc ttatcttcat
     7681 gagattgatg cctgcaaggt tcctgactgg gtttcaaata cggtatggta tcagatattt
     7741 cctgaaagat ttgccaatgg caatgctcta ttaaacccag aagggacttt agactgggat
     7801 tcatctgtca cacctaagag cgatgatttc tttggtggtg atttacaggg gattattgat
     7861 catatggatt acttgcaaga cttgggtatt actggactat atctttgtcc catctttgaa
     7921 tctgcaagca atcacaagta caatacgaca gattactttg aaattgaccg tcattttgga
     7981 gacaaggaga cctttcggga actggtggat caagcgcatc atcgtggcat gaaagtcatg
     8041 ctggatgcgg tatttaatta tattggttcg caatctcttc aatgaaaaaa tgtcgtcaaa
     8101 aatggtgaac agtctgctta taaggattgg ttccatattc aacaattccc agtgacaact
     8161 gaaaagctag ttaataagag agacttaccc tatcatgttt ttggtttcga ggattatatg
     8221 cctaagctaa atacagccaa tccagaggtc aagaattatc ttttaaaggt tgcgacttat
     8281 tggattgaag agtttaatat cgatgcttgg cgtttggatg tggctaatga gattgaccat
     8341 cagttctgga aggattttcg taaggcagtt ttagctaaaa atcctgatct ttatatccta
     8401 ggagaagtct ggcatacatc tcagccttgg ctaaatggag atgagttcca tgccgtcatg
     8461 aattatcctt tatctgatag tatcaaggac tatttcttac gaggaattaa gaagacagac
     8521 cagttcatcg atgaaatcaa tggagagtct atgtattaca agcagcagat ttcagaggtc
     8581 atgtttaatc tcttggattc acatgataca gagcgaatcc tgtggacggc caatgaagat
     8641 gttcaactgg ttaaatcagc cttatccttt ctctttttac aaaaaggaac accgtgcatt
     8701 tattacggaa ccgagctagc cttgactgga ggaccagatc cagattgtcg tcgttgtatg
     8761 ccttgggaac gtgtatcaag tgacaatgat atgctgaact ttatgaagag gctgattaag
     8821 attcggaaat acgcgtcagt aatcatttcg catggcaagt atagccttca agaaatcaaa
     8881 tctgatctag tagctctgga atggaaatac gaaggacgga tcctcaaagc aatattcaac
     8941 caatcaacag aagattatct tttagagaaa taagcagtag cactagcaag caattgccaa
     9001 gaattggaga atcagcttgt catctctcca gatggatttg tgattttcta aaaactagtt
     9061 gatgaagatt atggtacatt tcatatctta tatagtataa taaggctagt tactaaactt
     9121 gtaaaggaga acttaaatga attgtagagg acatgaaaca agacaaagaa ttgttagaga
     9181 ttttgaagtt tagcctaaag cacatattaa gctgttagca aatcaacaaa aacatagtga
     9241 tgcaggagca actattgaag atgaatatta tgtatttatc gctgagagta aaattgatgg
     9301 caagaaggaa gttattcagt gttgcatggg tgcggcaagg gattttttag aactaattaa
     9361 tcacaaaggg ctacctcttt ttaatccgct tgtaggtgat tctcatgtaa ataatagaca
     9421 agaatatgac aatacaggga gtggaaattt acaacctgaa aagtggaatg aaactgcaaa
     9481 gcagctttat aatgttataa tgtggttgat tattttatgg aatgctaagc cggatacacc
     9541 tttatttaat tttaaagacg aagtaattaa gtataaaaca tatgagcctt ttgaaagcag
     9601 tataaaaaga gtaaatacta ctataaagaa tggtagtaaa gggaaaactc tgactgagat
     9661 gattaatggc tacagagcgg ataacgatat tagagatgaa atttgtaact ttaatattct
     9721 gaaaaataaa attcgtgata tgaaagacca acaaggaaat acaatggaat cttactttta
     9781 gttattgttg aattttgggt attctataaa atatccta
//
LOCUS       DAVLHB010000064         9392 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLHB010000064 DAVLHB010000000
VERSION     DAVLHB010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.064"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(59..451)
                     /locus_tag="VXE36_001885"
     CDS             complement(59..451)
                     /locus_tag="VXE36_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0780126.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(750..1379)
                     /locus_tag="VXE36_001886"
     CDS             complement(750..1379)
                     /locus_tag="VXE36_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0780127.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(1424..1663)
                     /locus_tag="VXE36_001887"
     CDS             complement(1424..1663)
                     /locus_tag="VXE36_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780128.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(1813..2079)
                     /locus_tag="VXE36_001888"
                     /pseudo
     CDS             complement(1813..2079)
                     /locus_tag="VXE36_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(2104..2415)
                     /locus_tag="VXE36_001889"
     CDS             complement(2104..2415)
                     /locus_tag="VXE36_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0780129.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(2340..2581)
                     /locus_tag="VXE36_001890"
                     /pseudo
     CDS             complement(2340..2581)
                     /locus_tag="VXE36_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(2582..3214)
                     /locus_tag="VXE36_001891"
     CDS             complement(2582..3214)
                     /locus_tag="VXE36_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0780130.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(3228..4223)
                     /locus_tag="VXE36_001892"
     CDS             complement(3228..4223)
                     /locus_tag="VXE36_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0780131.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(4220..4918)
                     /locus_tag="VXE36_001893"
     CDS             complement(4220..4918)
                     /locus_tag="VXE36_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0780132.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(4995..6005)
                     /locus_tag="VXE36_001894"
     CDS             complement(4995..6005)
                     /locus_tag="VXE36_001894"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0780133.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(5989..6996)
                     /locus_tag="VXE36_001895"
     CDS             complement(5989..6996)
                     /locus_tag="VXE36_001895"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0780134.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(6983..7936)
                     /gene="mvaD"
                     /locus_tag="VXE36_001896"
     CDS             complement(6983..7936)
                     /gene="mvaD"
                     /locus_tag="VXE36_001896"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0780135.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(7918..8796)
                     /gene="mvk"
                     /locus_tag="VXE36_001897"
     CDS             complement(7918..8796)
                     /gene="mvk"
                     /locus_tag="VXE36_001897"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0780136.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(8918..9247)
                     /locus_tag="VXE36_001898"
     CDS             complement(8918..9247)
                     /locus_tag="VXE36_001898"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0780137.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFCKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFHRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
BASE COUNT         2784 a         2168 c         1634 g         2806 t
ORIGIN      
        1 cctaactaaa acactcataa agtatagaca attttagact actttggata tcttttggtt
       61 agtcattttc caaaactaat ttatctaatt tttcagttat atttgacttc atcttctcag
      121 taacatgagt ataaacactt aaaatctttg tttcattagt ataatctaca cgatccatta
      181 tcgctgttat aggtacttcc aattcagcaa gcaaacttat atgcgaatat ctaaaaacat
      241 gagcagtcaa tacaaaatca tctttcttaa tttcactttt cctaaaactg tttttcaaaa
      301 agtaattgaa acaagttatc attaagggag aaccattatt tgtaaatata taatcacctt
      361 cttctaaaag aagatattct tttaaaattt ctaacactct atcactaata ccaattactc
      421 tatatgaagc taaacttttc ggactatcca aaaatacttc gttattggac gattacatta
      481 tagtaaaacg aaataagaac aggacaaatc gatcaggaca gtcaaatcaa tttctaacaa
      541 tgttttagaa gtagaggtgt actattatag tttcaatcta ctatacaaga cgaaattgaa
      601 gaaatctttc cattataaaa cgcatattat caaggttttt aaacacctaa taatatgcgt
      661 tttttcctat tttaaagact tttatccacc tattatacaa agttaagtat ccatcacagt
      721 ttacaattag ccttcattac ctaacccatt caccatcctt caagagagta acctttaaga
      781 accgaataaa taaatggcaa atttcgttca tttaatttaa ctgcactgtt aatttgatta
      841 gctccatctc ctaaagtatg cactcctact acacggtgac tagcatcata aactgtagat
      901 ccactagacc cctctaaagt atcaacttgg taatccaaga acatgccatc atcacttaaa
      961 acttgttttt tatctgtata catttgatga attttaaaat tatatgatgg atagcctgtg
     1021 atagtcacag ttattcctgt caaatttttt tgactagtag gaagacccaa agtccctaat
     1081 tttgcaccaa tgggctcttc tagaattaat aaagccaagt catattccct tgcatcctta
     1141 gaatttaaat ttctaaattc cttcaaataa cgaacttcct ttactttgat ctttccaaat
     1201 agttcttgac ttggactaac agccggaaga acataaatat catccgcttc tttcccatag
     1261 tcatgtctgt agtagttgtg agccgctgta attaacacat tatctttaat aaaattcgca
     1321 cttcccctcc cttctacatt cattccatcg gctactccat aatacttaga taaaaccata
     1381 gctgaagtcg aatacggata ctgtaaagta ttatcaattt taatcaaatc atcattaccg
     1441 ataatacttc tgattgcttt tggtagtatg aaccatacgt tggtgaaatc tcagataatg
     1501 aagaatcatt agactctgga cctttttcta gtgtctcact tacctcatat tcttcacctg
     1561 tactagaaat aacactcaaa gcagatactg tcgataactg gctagccaat aaagtactcg
     1621 caataattga aatacccaat tttttataaa cagttttctt cattattgtg tcctcctaat
     1681 gtaattatag cgtactattc taaatttctt aatctactat agaatcaaga aatctaccac
     1741 cttctttaaa taccctccat tatcacataa acaggtaaac ttttcaatta atgactgcgc
     1801 ttttcaatca cgctagaggt acttacttgc ttctttgata ctaagttcag ccattctttc
     1861 cttgtttttc tcaataaagc atgttaccca agtgggattc gttttggagt agtctcgcag
     1921 agtccagcca atggctttat tgataaaaaa ttctgtttgg ttcaagttat gaaggagaat
     1981 cttttccatt aattgagtat tggtcttctc ttttcttaac aactggtggt caatagcgac
     2041 acgtctcagc cagatattat ctgataggct ccattttata ctcaatgaaa atcaaagagc
     2101 aaactaggaa gctagccgca gattgctcaa aacactgttt tgaggttgca gatagagctg
     2161 acgtggtttg aagagatttt cgaagaatat taagattatt tcttctagtt cagggtgttt
     2221 atacaccaaa ctccctacta ctcgatctag gatatctacc gtgtcccacc aggattttgt
     2281 cacgactaac tgctctagct taggcaaatc ggtttccttt agataagact gcattgcttt
     2341 caaatagtta gcagccacat attggtattt tctaggctcc ttttcccagc aagtgtctgc
     2401 aaaatcccaa tcgataatct ttgttttttt cgcttctgga aaatattttt atagagttta
     2461 tttctttcag gcaccgcaat acctagaaaa gaaaattgat ggcgcatata ggcttccatg
     2521 ggccttgctt tttagagtct tttgctgctt ctagctcctc aagtaaatct gctaaactca
     2581 tctaaaactc ctcttgcccc accaaatggt gctgaaaggc atagacagcc gcctgagtac
     2641 gatcgctgac ttcaagtttg gcaagaatgt tggacacgtg ggtcttgacc gtcttgagag
     2701 agataaagag gtcatctgcg atgcgctgat tttcgtagcc cttggcgatg agttggagaa
     2761 catctcgctc acgcgcagtc aattcttcat gaagttccat atgattgcgg tggtattcaa
     2821 ccttcttgct aacctcttgc tcaatggcca gctcgccagc agctacctta ctgacggcat
     2881 gaagcaattc atctgcacta gaagtcttga gcatatagcc tttggcacca gcatctaaga
     2941 ctggcatgat tttttcattg tccaaataag aggtcacaat caaaatcttg gcttcaggcc
     3001 attctttaag gattgctaag gtcgcgtcaa tcccattcat ctcaggcatg acaatatcca
     3061 tgacaatgac atctggacgc agttccaagg ccaagtcaat cccttgagac ccgttggacg
     3121 cctcacccac aacttctaca tcgtcttgga ggtcaaagta gcttttcaag cccaaacgga
     3181 ccatttcatg gtcatctact agtaaaattt tcatctttac tcctttatca ttccttatct
     3241 aacaggggaa tacggatatc aactgccaac ccttgcttgg gagctgttaa taactgaacc
     3301 gtccctgcca tatcttcaac ccgctccttg atatttcgca gtccataact caagtcgtct
     3361 aagctcccta actggaaacc aatcccattg tccaccacct tcagttgcaa ttcaacatct
     3421 gtctgataga ggtagacatc taggcaagat gcctgggcat ggcggagcgt attgctaatc
     3481 aactcttgca ggatacggaa gatatgctcc tcgattttct taggcaattt cgtcatattc
     3541 tgcttgagac taaccctaag atcactcttg tcctcaagct cttttaagag aatttgaatc
     3601 ccttctatca agctcttctg ctccagttca actggtcgca aatgcaagag caaaacccgc
     3661 aaatccttct gggcagtttc taaaatagct gtgacactct gcaactggat ctgcatcttt
     3721 tctctatcca atttcaaagc ctgctgactg atacccgata aaatcatgtg ggccgcaaac
     3781 aactcctgac tgactgtatc gtgcaaatcc cgagcaattc gcttccgttc cttctcgatg
     3841 atttcctctt cctgagcaag gctatgattt tcagcttttt gaagagcttc tgtcaaaagg
     3901 ttaagtttac ctgataagga cttgaaactg gcatccaaat ctggatctgc aacctgaacc
     3961 acttcttgcc ctgccaataa acgcttgaga ttagcctgca tttttcttag agaaagctct
     4021 tcgatccctc gccaaaacag ggctaagaga caggttatgg acatgctgaa aaccaacaat
     4081 aaaaagacaa atttttctgt tttttcgaca tcgtgcaaaa agatagacca gtcaaaatca
     4141 agtatttcca gcaagctgtg ggagaaaaaa aagacaaaca ggaaggaggt gagagcaata
     4201 atgacatagg cttgtttttt catcctctaa ccacctccac atcaccaatc atagtggtca
     4261 agaaaatctt gacactcttg ttactcttga gatagtcttt tgtttcttga tgatagtgtt
     4321 cattgcggag ggctcgcttg ggctggttga aaaaagtcaa atccccatag agacagttaa
     4381 cgctgagact gacttccaca tctacaggta caatgatttt ggtcgttcct accatctttc
     4441 tgaggataat gacattgtca tgattggtta agatgaccct ctccagatga atagtgtcct
     4501 tgcccatgaa gcgaaagaga ttgatatcat cgaattggca agtctggtag cttgaaaaat
     4561 gatgaagatt tccaaaccaa cgatttttct ccttcttaac cgtcacgacc tcttcaaaaa
     4621 ccaaattggt ctgctctttt tcctggttca tcatcgggta aagaagaaag aggctataga
     4681 taaccgcaac aaaaatagct agaatcacaa aaggattgag cataacgatg aaaaagaaga
     4741 gaatggttgc cgctactaaa agaagattat ttccctcttt accagtgtag tagcgaatca
     4801 aaagcaaaaa gaggaatagt atcagcagaa aacgcgaaaa atgctctgat accatcaaaa
     4861 tcagagctcc tgtcagaaga caggcttcga taaataaaaa gattttaaat tttctcatag
     4921 gttcatcctc tcccttctat tttatcacaa ttcaaaaaag tcacctcagt ctgaggatgg
     4981 aaaaaaggcg ctggttacgc ctttttcatc tgatcctttg cttcttttaa ttttccataa
     5041 agaagatagt ctactttttg tagatctgct atggtggcac agttaaggga acacataatc
     5101 aagcgtaggt ctgctttcca gccttggaca atgccaatca cttcttcaac tgtgtaggtt
     5161 tcaaccaatt ccagaacggt tcgtgacaat cccacagact tagcaccaaa aaccaagcac
     5221 ttaatcatat ccagcggatt ccgaacccct ccactaacca agagttcgac cttatctttc
     5281 cattcttggg cattgagaag ggcctgcatg gtagactgac cccattgatt gaggtaatca
     5341 cgctggccac tacgacggtt ttcgatatag gcaaagctgg tgccaccacg acccgatagg
     5401 tccactgtac gaacaccgaa ttcataggct ctttcgattg tcttggcatc cattccaaag
     5461 cccacttcct tgaggacaat aggaacggga atttgctcgc tataatctgc tagatgcgat
     5521 tgccagcttc taaacttcct ttctccctcg ggcatgagta attcctgcat gacattgaca
     5581 tgcacttgca atagaacagg attcatctct tctacagtct gaagtcctaa ctcgacaggc
     5641 ttgtccaatc caatattggt tccaaggagg agattgggat gactagactt gacagaaaaa
     5701 gaatcatccg ttggattttt gagggctgcg ctataagaac ccgttacaaa taaaatacca
     5761 caggattccg ccacctgagc cagcttttga ttgatttctc ttcccttatt acttccacca
     5821 gtcatggcat tgatataaaa aggaaagtcc cactttcgac cagcaaactc tgtcgaaaga
     5881 tcgatttcat ccagattgta aagaggcaag gaagaatgaa tcagctccac ctcatcaaag
     5941 ctattatagg aacttttctg ctcaagggca tagaggatat gctcgtcctt acgatttgtc
     6001 gtcatgtcct atcctttctt gatataagag ctcaatcccc agatcggccc aacgattttt
     6061 taaggttttg gttgattgcg catcaaaact caaggcgatg ccacagtcac caccaccagc
     6121 accactactc ttggcaacgg cctgcaaatc ttgactggct tctttcaact gtctaagcaa
     6181 aggcgtgtaa atatctgtac tcaagccttc taaaagcttg ctggctactt ctacttgctc
     6241 gataactttt tcggctttcc cctgctccaa ggcttcgacc aaagaaacca ccgtttcttt
     6301 tgaggaactt aaaaaatttt gattgatatt ttgcttgatt tgctggacca tgtgactcga
     6361 tacagccact tccttggtcc atcccactaa gaaatcacat tctaaagttg gtttcacttg
     6421 tgagataaaa aatccccaat cacgctccag aactgtcgcc aagttttctt cttctaacca
     6481 agcagccacc ttctggcgat caaatgactg gtagagaacc aaatcctctg ccacaataca
     6541 ggcaaggtcg cccatggaac cattgtctcc tcgcttgagc aagacagcgc tagtcagctt
     6601 gaacaagaga ttctgatcaa ccgaaagatt atagagagcc agtaaagcct tgacaaccaa
     6661 gacaacgacg ctgccactag aacctagacc aaactttttc ccttctcgtt ccattttgcc
     6721 acagattttt agggaaaaag gtcttaaatt ctgaccgcga acagcgagga agtctcccat
     6781 caaagcaatc gtttcttgaa tcaagctgta gtcaggatta ggccttaagt ccactgcgaa
     6841 atcaaacata tctgaataga tacggtagct gtcagaaaaa gcaatttcag ccctcatata
     6901 gatgggaata tcctttatca aagctaactg ccctggctct aaaatagcat attcacctgc
     6961 ccaatagagt tttccgcaag ttttaacagc aatcatcttg actcaaatcc tttgtttttg
     7021 acacaatcaa gcgataacgc tgaccgaaaa tttctgataa atgctccaag tctttctcct
     7081 gacagaagac cttaacattg ggaccagcat ccatggtaaa gtagcaggcc tctcctttct
     7141 cacgaagctg gcgaacaaag tccatagcct cataagaggc atccgtcaga taagaaaagg
     7201 ctggactagc agtctttgtc gtagcatgca tagccagggc atttttctcc gttaattctc
     7261 caatcttggc aaaatcattt tccttgagat aaatcagcat atcctgatag tccttctcag
     7321 actgacgaac ccagtcgtcg aaagtcgtcg aggtttccac acaaagtttc atcccgtcac
     7381 ggctagagat tggttttttc ttgtcctcta gcaccaacat aatcatagct agtttcaagt
     7441 ctgtctctac agggtaaatt tctccactat ccttatccca ggctcctagt ggtccataaa
     7501 aactccgaga agaagagcct gaggcaaact tggcttcctg cgctaactga cttctatcca
     7561 atccaagctt gaaataagca ttacaagcct tgaccagggc ggacaaacca ctagaacttg
     7621 aggacaggcc cgctgccgta ggcatattgt tttgagtatc gatacggaca aagccctcac
     7681 cagctggacg ataacggtca ataatcttac tcatcttggc atgctcgacc tcattttgta
     7741 gctgaccatt gatgtaaaat tcgtcagctg ttacattggc tggtaaaggc gacaaggtcg
     7801 tctctgtata catattttcc aaagttagag aaatactgct agtagcaggc accatctctt
     7861 tttctttttt ctttccccaa tatttgataa tagcaatatt tgcgtaggaa cgtactgtta
     7921 caggctctct atccatgtct gaacagctcc tttctcttct aatctttctg ctagttcttg
     7981 tgcgtgtgtc aaattggtta ccaaggctat gatacaacct cctagcccac caccgctcat
     8041 cttggcaccc agagcaccat ggctaagagt cgtttcaacc aaaaagtctg cctcagggct
     8101 actgactcca atttctttta aatgtaaatg cgcttgactg aggatttgtc ccagtccttc
     8161 agcatctttt tgtgaaatcg caacttctgc ttgctgggtt aattctccca aggcatgcaa
     8221 aaacggtagg gcatccttgc ccttattttg aaccacttgg atggcttcac gagtatgacc
     8281 ataaacaccc gtatcggcaa tcaccaaata ggcggataaa tccatctcaa gttctgtaaa
     8341 tcctacgttc ttgataaagc gaataggttg gtcactgaga caggtcttag catccaaacc
     8401 actaggattc atatgggcaa tcatttcagc tcgattgacc aagatttcta gtacatcatg
     8461 aggcagatca gcctgatagt agtcaaatac cgcacgaatg gccgctatgc tgatagccgc
     8521 tgacgaaccc atcccccgtt tctcagggat agccgagtca atctcacaac gaatgcaggc
     8581 ttctgtgata tccaaatact ccagtgaggc ataaaccgcc atggacaagg tatcctcctc
     8641 ataaaggcgc caaggactct ctgcaggaac taccttacag gtcacctcca cctccaaaag
     8701 aggcagggaa atggcaggat aaccgtaaac gaccgcatgt tcccctatta aaattatctt
     8761 actatgtgcc tgaccgacac caactttttt tgtcattttt tccttttact agacgaaaaa
     8821 acgtcttatt tttcatacaa gtattaattc tttcctatct attttattat attttcacaa
     8881 aaaaagcgat tgtttccatt cacaatcgct tctttcatta ccgaacccat tcaccattat
     8941 aattgacaga atagccatct acagtcgtat tcactgccaa ggcacctgag ctataagcgt
     9001 agtaccatct gccattgacc tggaaccaac ctgtcgtcat agaacgatga aagaaactcc
     9061 ataccattaa gtaaagagga aagtcatgag ggagcatgcg ccattgacaa cctgttttag
     9121 tgacgtacaa agtttcatta acaagtactc gtttcggcca tttataggtg cggtgtttgc
     9181 agaaataggg ttcaatcttc gcccattctt gatcgtttaa atcagtatca tatgctttgc
     9241 gtgtcataac tctagtttaa catttttttg tgaatacagg ttctaaataa tcgaccacga
     9301 aaatttctta agtggaaaac gccttatgaa gtatgctacg ggaaacttat gcacttaatt
     9361 tgacaactca atatgtaaaa atatatacta ta
//
LOCUS       DAVLHB010000065         8799 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLHB010000065 DAVLHB010000000
VERSION     DAVLHB010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8799
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.065"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..529
                     /locus_tag="VXE36_001899"
     CDS             <1..529
                     /locus_tag="VXE36_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0780138.1"
                     /translation="ERVELIKEDLIINESVLNIDKKGYELICLQHPVSYDLRRIISVI
                     KISTDIERIGDRIVEILKNLQILQNNEILKKIISKIKILHEVIGLHMNRAISCYREEQ
                     SGCLDMVVIQKQNEIEELSINMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQ
                     AIYKWIMYRKYGNIN"
     gene            542..2017
                     /gene="galT"
                     /locus_tag="VXE36_001900"
     CDS             542..2017
                     /gene="galT"
                     /locus_tag="VXE36_001900"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0780139.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            2030..3040
                     /gene="galE"
                     /locus_tag="VXE36_001901"
     CDS             2030..3040
                     /gene="galE"
                     /locus_tag="VXE36_001901"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0780140.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIEAAIHFAGYKAVGESVQKPVMYYENNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGVHNHSPLIETMPTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPFIAQVAVGKRPELSVFG
                     DDYDTVDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKVPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3224..3883
                     /locus_tag="VXE36_001902"
     CDS             3224..3883
                     /locus_tag="VXE36_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0780141.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3908..4975
                     /locus_tag="VXE36_001903"
     CDS             3908..4975
                     /locus_tag="VXE36_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0780142.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIPGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSISGLSGGTGRAILASILVRYLDDKGELGVSEKGWEVAKEYLKNAYTL
                     QKGESSIVKMLDKEDPIQYGMMWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            5078..6088
                     /locus_tag="VXE36_001904"
     CDS             5078..6088
                     /locus_tag="VXE36_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780143.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            6100..7791
                     /locus_tag="VXE36_001905"
     CDS             6100..7791
                     /locus_tag="VXE36_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0780144.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7794..8504
                     /locus_tag="VXE36_001906"
     CDS             7794..8504
                     /locus_tag="VXE36_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0780145.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            8600..>8799
                     /locus_tag="VXE36_001907"
     CDS             8600..>8799
                     /locus_tag="VXE36_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780146.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYID"
BASE COUNT         3007 a         1191 c         1719 g         2882 t
ORIGIN      
        1 agaacgagta gaattgatta aagaagattt aatcataaat gagtcagttc taaatattga
       61 taaaaaagga tatgagttaa tttgtttaca acatcctgtt tcatatgact taagaagaat
      121 tattagtgta ataaaaatat caactgacat tgaacgtatt ggggatagaa ttgttgaaat
      181 tttaaaaaat ctacagattc ttcaaaataa tgaaattttg aagaaaatta tttcaaaaat
      241 aaaaatactt catgaagtta tcggactgca tatgaatagg gctatatctt gttatagaga
      301 ggaacaatct ggatgtttag atatggttgt tatacaaaaa cagaatgaga tagaagagct
      361 tagtataaat atggaaaaga aaataatgaa ttacatattt gaagatgatg ggaacgtttc
      421 tgaagtaatt agtgctttag atattattca tcaccttgat aaaattgctc atactacgca
      481 agcaatttat aaatggataa tgtatagaaa atatgggaac ataaattaga aagaaaaata
      541 tatgaaaaca attattgata attttgttga tagagtaatt gaatacggaa tgtataatga
      601 aattgacaaa atatatgtga aaaatagagt actagcgtta ataggtgagg agggaattga
      661 tcgcatttcc gatgaaaatg acctgaaaca aataaaagat tacttagtgg aaatcgcctt
      721 aaaaaacggt aaaattaaag atttaatcga ggaaaaggaa tgtttaggag cagagttaat
      781 gaatttcata gttcctttac ctagtcgatt aaatgatatt ttttggagtt catatgatat
      841 atcacctcaa gaagcagttg aagagtttta taagttaagt aaagatagtg attatattaa
      901 aacttctgct attgctaaga atattgagtt tcgagcatca actaaatacg gagagctaga
      961 gattacgata aatttgtcaa aacccgaaaa agatccaaaa acaattgctg ctgaaaaatt
     1021 agtaaaagca actaattatc ccaaatgttt actatgtatg gaaaatgaag gatatcaggg
     1081 gcgaataaat tatccagcac gttcgaatca tagaattatt cggttgaaac ttggtgacga
     1141 agtatgggga ttccagtatt ctccctactc atactttaat gagcatgcga tatttttgaa
     1201 tagtcaacat gtaccaatgg ctattacctc taaaacattt gaacaattat tggagattgt
     1261 tgatattttg ccaggatatt ttgctggttc aaattctgat cttcctatct caggaggctc
     1321 cattcttagt cataaccact accagggagg gaaacatatt ttcccaatgg aaaaagcaaa
     1381 atttgagagt gaattttgtt ttaaagactt tgaggatgtt aatgctggta ttgtaaaatg
     1441 gccaatgtca gtaattaggt tacaaagtga aaataaaaat cgcttgttag atttagctac
     1501 taaaattcta aataagtgga gagaatattc agatttagaa gtagacatca ttgctatgac
     1561 tgaagatgtc ccacaccata cggtgactcc tattgctcgt aaagtggacg ggagatacga
     1621 attagatatt gttctaagag ataatcatac tactgaacaa tacccagatg gtgttttcca
     1681 tcctcatcaa gatgtacaac atattaaaaa ggaaaatatc gggttaatcg aagtgatggg
     1741 acttgcgata ttaccacctc gtttgaaacc agagttagaa gaagttggaa aatatctttt
     1801 aggagaggat aatgcaattg cggattatca tttagaatgg gccgaccaat tgaaagaaaa
     1861 atatcctcgc attaataaag aagaggttaa tagcgtagtt caacacgaag caggacaagt
     1921 gtttgcgaga gttctggaag atgcaggagt ttataagaat acaccgtctg ggcatgaagc
     1981 gtttatgaga tttgttaagt cggttggaat taattaggag gaaacaaaaa tggcaatatt
     2041 ggtaacaggc ggagctggtt atattggtag ccataccgta gtagaattac taaatttagg
     2101 aaaggaagtc atcattgtcg acaacctttc gaactctagc atcttggtgc tagaccgtat
     2161 tgaagcaatt acaggaatac gtcccgtgtt ttacgaatta gatgtttgtg ataaaccagc
     2221 attgagaaaa gtttttgaac aagaatctat tgaggctgca attcattttg caggatacaa
     2281 agctgtcggc gaatccgtgc aaaagcctgt aatgtattac gaaaataata ttatgagcac
     2341 attagctctt gttgaagtga tgtcagagtt taatgttaaa aagattgtat tttcatcgag
     2401 tgcgactgta tacggcgttc acaatcattc tccccttatt gagacgatgc cgacaagtgc
     2461 aacgaatccg tatgggtaca caaaagtgat gcttgaacaa attttaaaag atgttcatgt
     2521 agcagattca gagtggagta ttgcgttgct tcgttatttc aatccgattg gtgctcatga
     2581 gtcggggttg attggagaag atccatcagg cattcctaac aacttaatgc cttttattgc
     2641 acaagtagcg gtaggtaagc gaccagagct aagtgttttt ggagatgatt atgatacggt
     2701 agatggtact ggtgttcgcg attatatcca tgtagtggat ttagcgatag ggcatataaa
     2761 agctttagaa aaagtatctg aaaaaacaga tgtttatatt tataaccttg gttcaggaga
     2821 aggcacaagt gtattacaac ttgtaaatac atttgaaagt gttaataagg ttccaattcc
     2881 gtataaaatt gtaccaagac gatcaggaga cgttgcgact tgttatgcaa atgcagacaa
     2941 agcatataag gaattaaatt ggaggacaac aaaatcgatt gaagacatgt gtagagatac
     3001 atggaattgg caatcaaaaa atcccaatgg ctataattga tgatactgtc tatatgagtg
     3061 ctgtattttg gaaaaattac ttaacctttt aatgaaatgc atatttaatg aaagataaat
     3121 ttttttaaaa aaatgtttga aagcgcttga caaagtgaac ggtttcattg tataatgtaa
     3181 acataatgac accgatgtca aatataaaaa agagggtctt tatatgaaaa acctaacaaa
     3241 aattaagttc aaagaaaatg gagaatttaa tcattttcca ggaaatactg ttgtagcaaa
     3301 tctttatact aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga
     3361 attaccattt atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat
     3421 tgaattgttg tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctcttga
     3481 tacaccttta caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt
     3541 ggatgaagaa attcatatgc gtgtgactga aatgggaaaa caaaacatac tagttgaacc
     3601 tgcagatgaa gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc
     3661 aggtgttcgt ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg
     3721 gattcctcta accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga
     3781 aattttatta gagaagattc caactattac tgtaaaccgt attgactata ctgtatttga
     3841 agatatgaga caatttgttc catatcatga aaaatttaaa taaaataata aaaaaggaga
     3901 acttatcatg aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac
     3961 tacacttgct gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa
     4021 agctgataaa agtcaagaat tagtaatcta ttcgaactca gtctcaaatg gtcgtggtga
     4081 ttggttaact gctaaagcaa aagaagctgg ttttaatata aaaatggttg atatccctgg
     4141 cgctcaatta gcagaccgtg ttattgccga aaagaataat gcagttgcag atatggtatt
     4201 tggaattggt gctgttgatt caaataaaat tagagatcaa aaattactag tacagtacaa
     4261 gcctaaatgg ctagataaaa ttgatcaatc tttatcagat aaagataatt attataatcc
     4321 tgtgattgtt caaccattag ttttaattgg ggcgcctgat gtaaaagaaa tgcctaaaga
     4381 ttggactgaa ttaggtagta agtataaagg taaatattca atttctgggc tctcaggtgg
     4441 aacaggacgg gcaattctag caagtatctt agttcgatac cttgatgata aaggtgaatt
     4501 aggtgtttcc gaaaaaggtt gggaagtagc aaaagaatat ttgaaaaatg cctatactct
     4561 tcaaaaggga gaaagttcaa ttgttaagat gttagacaaa gaagatccaa tacaatatgg
     4621 aatgatgtgg ggttctggag cgttaatcgg acaaaaagaa caaaatgttg aattcaaagt
     4681 tatgactcct gagattggtg taccatttgt aactgaacaa actatggttt taagcactag
     4741 taaaaaacaa gcgttagcta aagaatttat tgattggttt ggtcaatcag aaattcaagt
     4801 agaatatagt aaaaaatttg gatctattcc tgcaaataaa gatgccctaa aagagttacc
     4861 tgaagatacg aaaaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt
     4921 tggaaagcat ttggatgaat gggtagaaaa agctgaatta gaatacgtaa aataagaaat
     4981 aagagttatt ttttatgtcc aagtctctct attatttcta aatttaagga agaaataaag
     5041 agaggctttt ggtttagtaa tagagggagt tagtgagatg attaaatttg ataatattca
     5101 aattaaatat ggtgattttg ttgcaattga taatctgaat ttagatatac atgaagggga
     5161 attctttaca tttcttgggc cttcaggatg tggtaaatca actactttga gagcattggt
     5221 aggtttttta gatccatcat caggaagtat tgaagttaat ggaacagatg tcactcattt
     5281 ggaacctgaa aagcgtggaa ttggtattgt atttcaatct tatgcgctat ttccaactat
     5341 gactgttttt gataatattg catttggttt aaaagttaag aaggtagctc cagatgttat
     5401 taaagctaaa gtatcagcag tggcagcaaa aattaagatc tctgatcaac agttacagcg
     5461 taatgtatca gaattatctg ggggtcaaca acaaagggta gcattggctc gtgctctggt
     5521 tcttgaacct aaaattcttt gtctagatga accattgtca aaccttgacg caaaattacg
     5581 tgtagatttg agaaaagagt tgaaaagact tcaaaaagag ttaggtatta ctactttata
     5641 tgttactcat gatcaagagg aagccttgac tttatctgat agaattgcag tctttaacaa
     5701 tggatacatc gaacaggtcg gtacaccagt agagatttat cataattctc aaactgaatt
     5761 tgtatgtgat ttcattggag atattaatgt tttgaccgat gaaacagtcc acgaagtatt
     5821 attgaaaaat acaagcgttt tcttagagga taaaaaagga tacattcgat tagagaaagt
     5881 tcgattcaat cgtgaaactg aacaagattt tattctaaaa gggacaatta ttgatgttga
     5941 gttttctgga gttacaattc actatacaat aaaagtttct gaaagtcaga ttcttaatgt
     6001 aacaagtatt gatagtcagg ctgctattag atctgtcgga gaaagtgtgg aattatttat
     6061 cacaccatca gacgttctgc aattttaagg aggtgcagta tgcgtcataa attaaattta
     6121 aaagattggc ttattcgttt agggttaatc tggttcttag taacatttat tatttatcca
     6181 aactttgatc tagtagtgaa tgtatttgta aaaggaggag aattttccct tgatgctgta
     6241 catcgtgttc taaaatctca gagggcactt cagagtatta tgaacagttt taagttagca
     6301 ttttcactta ttattacagt taatgtcgta ggtattcttt gtgttctatt tacagagtac
     6361 tttgatatta aaggtgctaa aattttaaaa ttaggttata tgacctcttt aatttatgga
     6421 ggagtggttt tagcgactgg atataaattt gtctatggtc cttatggatt gattacaaaa
     6481 tttttacaaa atgttatccc ttctttagac tctaactggt ttattgggta tggtgcagtc
     6541 ttattcatta tgacattttc aggaactgct aatcatacat tgtttttaac aaatacaatt
     6601 cgaagcgttg actatcacac tattgaggct gctcgaaata tgggagcaaa accatttact
     6661 gttttccgaa aagtagtgtt accaacctta attccaactc tatttgcact tactattatg
     6721 gtttttctta gtggtttatc tgcagtagca gcacccatga ttgttggtgg taaagaattt
     6781 caaactataa atccaatgat tattacattt gcagggatgg ggaattctcg tgatttagct
     6841 gccttacttg caattatttt aggtattgca actacaattt tgcttactat catgaataag
     6901 atagaaaaag gtggaaatta tatttctatc tctaagacta aagcgcctct taaaaaacaa
     6961 aaaattgcgt ctaagccttg gaatatcatt gctcacattg tagcatatgg attgttcaca
     7021 gttttcatgc ttccactaat ttttatagta ttatactcat ttacagatcc agttgcaatt
     7081 caaacaggta acttaacatt atcaaacttt actttagaaa attatcgctt attctttagt
     7141 aatagtgcgg cattctctcc attcttggtc agctttattt attctattat tgctgcgaca
     7201 acagcaacaa ttctcgcagt tgtatttgct cgtgttgtca gaaaacataa atctcgtttt
     7261 gatttcttat ttgaatatgg tgctctactt ccttggttac taccaagtac acttttagca
     7321 gtaagtttat tatttacttt taatcagcca caatttcttg tcttgaatca gattttggta
     7381 ggtagtttgg taattctact tattgcatat atagttgtaa aaatcccatt ttcttataga
     7441 atggtacgtg ctattttatt tagtgttgat gatgagatgg aagatgcagc aagaagtatg
     7501 ggtgcttcac ctttttatac tatgatgaag gttatcattc catttatttt accggttgtt
     7561 ctctctgtta ttgctttaaa ctttaactct ttattaactg acttcgactt atctgtattc
     7621 ctttaccatc ccctagctca accattaggt attacgattc gatctgcagg tgatgaaaca
     7681 gcaacatcta atgcacaagc tctggtattt gtttatacaa ttgttctgat gattatttct
     7741 ggaacggtat tatacttcac acaaagaccg gggcgtaaag taaggaaata atcatgacag
     7801 ccactagtct tgggttatca aatattgaaa tagttgtcag gattgtttta tcagtagtca
     7861 ttggtagtat aattggttta gagagaggga gcaaatccca gcctgcaggc atccgaactt
     7921 atagtattgt ttgtctagct gcatgtttga ttatgatgac gaatgaatac gtatcttata
     7981 aatttgggac aggagatcct acacgattag gagctcaagt tatatcaggt gtgggttttc
     8041 taggcgctgg aacgattctt attacagata aaaagaaaat tacaggtctg acaactgcag
     8101 caggcatttg ggcttcggca ggaattggat tagctattgg agtaggtttt tatgagggag
     8161 ctcttttagt agccatttct gtttggggtg tgatatccat gttccaacca ctaaaaaaat
     8221 atctgcaaaa tcgttctaaa atgattgaat tgtatatagt ggttaaatct acagaagcct
     8281 ataatcgtgt attggtttat tgtgcagaaa atggtatcag aatgaccgat tcaagaacag
     8341 cgtttggaga tgttaattct gacagaattg aatactttga tgttccggac aaaaaaatag
     8401 cgtcatttat tactctggaa ttatcaggta gatttgaaca tcttcgactg atggaagaaa
     8461 ttgctaatat tgtaggtgtt atttatgtcg aagaaattag ctgaaattta gtaaacaaag
     8521 ggacagatgt ttttgtcctt ttgtttttta gatgttttaa tcatctaatt tttgagtaga
     8581 tttttgctca gaggttttta tgaaagatta taaaatcaat tttgatttag gtaaaataga
     8641 atattttgat aataattgtt tgatacaagt atacaaattt atttcttttt atgatatttg
     8701 tgaaatggtg tttgcctttc atttacctcc tgatgagttg ataacaaatg ttatctttaa
     8761 agaaaaaatt aactctatgt taaaatgtta cattgacag
//
LOCUS       DAVLHB010000066         8025 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLHB010000066 DAVLHB010000000
VERSION     DAVLHB010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.066"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            96..329
                     /locus_tag="VXE36_001908"
     CDS             96..329
                     /locus_tag="VXE36_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0780147.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            329..1663
                     /locus_tag="VXE36_001909"
     CDS             329..1663
                     /locus_tag="VXE36_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0780148.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            1673..1927
                     /locus_tag="VXE36_001910"
     CDS             1673..1927
                     /locus_tag="VXE36_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0780149.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            2023..2418
                     /locus_tag="VXE36_001911"
     CDS             2023..2418
                     /locus_tag="VXE36_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0780150.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            2918..3280
                     /locus_tag="VXE36_001912"
     CDS             2918..3280
                     /locus_tag="VXE36_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780151.1"
                     /translation="MLAMEQAGFISHQEKLERLGVHYEISERTQTPILDACPLVLDCR
                     VDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKR
                     VDMKGSFIKKARKKDGKN"
     gene            3267..3827
                     /locus_tag="VXE36_001913"
     CDS             3267..3827
                     /locus_tag="VXE36_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0780152.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            3827..4405
                     /locus_tag="VXE36_001914"
     CDS             3827..4405
                     /locus_tag="VXE36_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0780153.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            4398..7049
                     /locus_tag="VXE36_001915"
     CDS             4398..7049
                     /locus_tag="VXE36_001915"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0780154.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRVLEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNDLAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPVFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            7119..7874
                     /locus_tag="VXE36_001916"
     CDS             7119..7874
                     /locus_tag="VXE36_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0780155.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
BASE COUNT         2397 a         1564 c         1848 g         2216 t
ORIGIN      
        1 acaacctcaa agcactgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt attagaacat acaatggagg tcgtcatgga caatatcatc gatgtgtcaa
      121 ttcctgttgc agaagtggtg gacaagcatc cagaagtctt ggaaattcta gtggagttgg
      181 gttttaaacc ccttgccaat cccttaatgc gcaatacagt tggtcgtaaa gtatcactta
      241 aacaaggttc taagctagca ggaactccta tggacaagat tgtacgcaca ctggaagcga
      301 atggctacga agtgattgga ttagactaat ggcagatgaa cggattcatg tcctacggga
      361 tattttatta gaattgcata atggcgcctc tcctgagtcg gttcaggagc gttttgatgc
      421 gacctttgcg ggtgtctcag ccatcgagat ttcccttatg gagcacgagc tgatgaactc
      481 agactcaggt gtcacctttg aagatgttat ggaactctgt gatgtccatg ccaatctttt
      541 taaaaatgct atcaaaggtg tcgaagtttc agatactgag catccaggtc acccagttcg
      601 tgtcttcaaa gaagaaaatc tggctctccg tgcggccttg attcgcattc gtagattgtt
      661 agatacctat gagtctatgg aagacgagga aatgctggcg gagatgcgta agggtttggt
      721 gcgtcagatg ggacttgtgg gtcaatttga catccattac caacgtaagg aagaactctt
      781 ctttcctatc atggagcgct atggacacga ttcacctccc aaagttatgt ggggagtgga
      841 tgatcagatt agggaactct ttcaaacagc tctaacgaca gccaagtcac taccagaagt
      901 gtcaattagc agtgtaaagg aagcttttga agcttttgcg acagagtttg aaagtatgat
      961 tttcaaggaa gagtccatcc tcctcatgat tctccttgag tcttttactc aggatgactg
     1021 gcttcagatt gcggaggaga gcgatgccta tggctatgcc atcatccgtc cgtcagagaa
     1081 atgggtgcca gaacgacaga gctttattga ggaaaagatt gcagaggagc ctgtacagct
     1141 agatacggca gaaggtcaag ttcaacaagt catagatacg ccagaaggcc attttaccat
     1201 tacctttacc cctaaggaaa aggaagctgt gctggaccgc catagtcaac aggcttttgg
     1261 taatggctat ctttcagtcg agcaggccaa tctcatcctc aatcatctcc ctatggagat
     1321 tacctttgtc aataaagaag atattttcca gtattacaat gacaatacgc cagctgatga
     1381 gatgattttc aaacggacgc cgtcccaagt cgggcgcaat gtcgaactct gtcatccgcc
     1441 taagtatttg gacaaggtca aggctatcat gaagggactt cgtgagggga ccaaggacaa
     1501 gtatgaaatg tggttcaagt ctgagtcgcg aggcaagttt gtccacatca cctatgctgc
     1561 agtacacgat gaaaacggag aattccaagg tgtactggaa tacgttcagg atatccagcc
     1621 ctaccgtgag attgatacgg actatttccg tggattagaa taaggagaaa aaatgagtta
     1681 cgaacaagaa tttatgaagg aatttgaagc ttgggtcaat acccaaatca tgattaacga
     1741 catggcgcac aaggaaagcc aaaaagttta cgaagaagac caggacgagc gtgccaaaga
     1801 tgccatgatt cgctacgaga gtcgcttgga tgcttatcag ttcttgcttg gtaagtttga
     1861 aaacttcaaa gtaggcaagg gattccatga tttgccagaa ggcttgtttg gtgagcgaaa
     1921 ttattaaacg agaaagattc ttgatttttc actaaaatct tgatagaatg tttatgttaa
     1981 atccttgtca gagcagggat tttttattga aaggatttta tcatgtcaaa gaaactcaat
     2041 cgtaaaaaac aattacgaaa tggcctccgt cgcgcaggtg ccttttcaag tactgtgact
     2101 aaggttgtag atgagacaaa aaaagtcgtg aagcgtgcag aacagtcagc aagcgcagct
     2161 ggtaaggctg tttctaaaaa agttgaacaa gcagtagaag ctaccaaaga gcaagctcaa
     2221 aaagtagcta attctgtaga agattttgca gcaaatttgg gtggacttcc acttgatcgt
     2281 gccaagactt tctatgatga aggaatcaag tctgcttcag atttcaaaaa ctggactgaa
     2341 aaagaactcc ttgacttgaa aggaatcggc ccagctacca tcaagaaatt gaaagaaaat
     2401 ggcatcaagt tcaagtaatt tttcttgagc cttgcatttc cgaaaaaatc ttgctacaat
     2461 agagccatta gaggtgtttt gaatcccaca ttttacagaa agtggcggcg ctgagaagtc
     2521 cacaaatgtg tcaaaactgg ttgctaatgg atgaaaaatt gaaataaaag tgtctttttg
     2581 ctttaaagac gagagttgcg ggcaactgcc cgaaattggg tggtaccgcg gataaacaca
     2641 ttcgtccctg tcatgtagat ggcagggctt ttcttttacg tcttagtcaa agggggttgt
     2701 tatgaagcaa tcttttaaca caagtaaact atattatggt tttcctgttt ttattttagg
     2761 atatcaagat tagaattttg gctataacat cacgacctgt agttcctctt atagtctagg
     2821 agattgggtt gtgattggag tcgttgcgag agagaatgcc gcagagtaga tcaaacagta
     2881 tcaaaaattt actgtgaata tttctgatga aacttctatg cttgcgatgg agcaggctgg
     2941 ttttatcagt catcaggaga aattggaacg tttgggagtg cattatgaaa tttctgaacg
     3001 aactcagact cctattttag acgcctgtcc acttgtttta gattgtcggg tagataggat
     3061 tgttgaggaa gacggtattt gccacatctt tgccaagatt cttgagcgac ttgttgcccc
     3121 agaactcctg gatgaaaagg gacattttaa aaatcaactg tttgccccaa cctatttcat
     3181 gggagatgga tatcagcgcg tttatcgcta tctggacaag cgtgtagata tgaagggcag
     3241 tttcatcaaa aaagcgagga agaaggatgg caagaactga gctgccagat aaaatcgaaa
     3301 cagaacgtct cgttttacga gtccgtactg tggcggatgc tgaggatatc tttgactatg
     3361 ctagtttgcc agaggtcgcc tatccagcag gttttcctcc agtcaagacc ttggaagatg
     3421 agatttatta tctggagcac attcttccgg agcgtaatca aaaggaaaat ctcccagcag
     3481 gctacgggat tgtcgtcaaa ggaacggata agatcgttgg ctctatctat ttcaaccatc
     3541 gccatgaaga tgatgtgatg gaaatcggct ataccttaca ctcagactat tgggggcgag
     3601 gttatgtgcc agaagctgcg cgtgccttga ttgacttagc ctttaaagat ttgggtcttc
     3661 acaagattga actaacttgc tttggatata accttcaaag tcaacgagtc gcggaaaagc
     3721 ttggctttac cctcgaagct cgcataagag accgtaaaga tgctcaaggc aactgctgtg
     3781 atgatttgag atatgccttg ctgaagagtg agtggggggt gatttgatgc atcttttcat
     3841 cattggtgct ccagcatcag gaaaaatgac cattggtcaa gaattatctc gactgacgga
     3901 tgctacccta ttttataacc atcaagccat tgattttgca ctagaaatct atcaggacta
     3961 tacagaggaa atgtgggaat ttgttcgtgg aatcactttt tcattccttg gagcaagtgc
     4021 aagaaatcag cgatcagtaa ttttaacaga tgtaattgat ttttcaaatc agtatcatct
     4081 gatatattta aagcaaattc agaatttgtt ggatgattat catcaagaga ttctttttgt
     4141 tgagttggaa acaagtcttg aagagtgcat acgtcgaaat cgaacggaga atcgattaaa
     4201 gcacaaaccc ttaaaacgac atattgaggt atctgaaaga gaaattttag agaccgctga
     4261 aacacttcaa ttaaattccc aatatcaacc gaatgagttg caccactact ttaaaataaa
     4321 taatacgaat ttgtctgcag aagaagctgc taagcaaatt caaaataaaa taaacaaaat
     4381 agagaaagga cacacacatg tctaaagaac tttcatctaa atacaatcca gccgaggttg
     4441 aggctggtcg ttaccaaaaa tggcttgatg ctgatgtttt caagccttca ggcgatcaaa
     4501 aggctaagcc ttattcaatc gttattccac caccaaacgt tacaggtaaa cttcaccttg
     4561 gtcacgcttg ggatacaact ttgcaagata ttatcatccg tcaaaaacgc atgcaaggtt
     4621 ttgataccct ttggcttcct gggatggacc acgcagggat tgccactcag gctaaggttg
     4681 aggagcgctt gcgtggtgag ggcatttccc gctatgacct tggtcgtgag tctttcttga
     4741 cgaaagtctg ggaatggaaa gacgaatatg ccactaccat caaggaacaa tggggcaaga
     4801 tggggctctc tgtagactat tctcgtgagc gtttcactct tgacgaaggt ttgtcaaaag
     4861 ctgttcgtaa ggtctttgtg gacctttaca agaaaggctg gatctaccgt ggtgagttta
     4921 tcatcaactg ggacccagca gctcgcacag ccctttctga tattgaggtg attcacaagg
     4981 atgtggaagg tgccttctac cacatgaatt acatgctgga agatggttca cgcgtccttg
     5041 aagttgctac aactcgtcct gagaccatgt ttggggacgt tgcggttgcg gtcaacccag
     5101 aagacccgcg ctacaaggac ttgattggta aaaatgtcat ccttccaatc gctaataaac
     5161 tcatcccaat cgttggagat gagcacgcag atcctgagtt tggtactggt gtcgtgaaaa
     5221 tcacacctgc ccacgatcca aatgacttct tggttggcca acgtcataac ttgccacaag
     5281 tcaacgtcat gaacgacgac ggaaccatga atgacttggc ctttgaattt tcaggcatgg
     5341 accgttttga agctcgtaag gcagtcgttg ctaagttgga agaaatcggt gccctcgtca
     5401 aaatcgaaaa acgtgtccac agtgttggtc actcagagcg tacaggtgtt gtggttgaac
     5461 ctcgcttgtc tactcaatgg ttcgtcaaga tggaccaatt ggctaagaac gccattgcca
     5521 accaagacac agaggacaag gtcgaattct acccacctcg tttcaacgat accttccttc
     5581 aatggatgga aaatgtccac gactgggtta tctctcgtca gctttggtgg ggtcaccaaa
     5641 tccctgcctg gtacaatgct gatggtgaaa tgtatgtcgg cgaagaagct ccagaaggtg
     5701 acggatggac tcaggacgaa gacgtcttgg atacttggtt cagttctgcc ctctggccat
     5761 tttcaaccat gggctggcct gaagtcgact cagaagactt taaacgttat ttcccaactt
     5821 caaccttggt aacaggttac gacatcatct tcttctgggt gtctcgtatg atcttccagt
     5881 cattggaatt cacaggccgt caaccattcc aaaacgtcct tatccacggt cttattcgtg
     5941 acgagcaagg acgcaagatg tctaagtctc tcggtaacgg gattgaccca atggatgtta
     6001 tcgagaaata cggtgccgat gcccttcgat ggttcctttc aaacggttct gcgccaggac
     6061 aagacgtgcg tttctcttat gagaaaatgg atgcttcatg gaactttatt aacaagattt
     6121 ggaacatttc tcgctatatc ctcatgaaca atggaggttt gacgctggat gtggcgcatg
     6181 acaatgtcac aaaagttgca acaggtgagg ctggtaatgt gacggaccgc tggattctcc
     6241 acaatctcaa cgaaaccatt gcaaaagtta ctgaaaactt tgataagttc gagtttggtg
     6301 tggctggtca tatcctttac aacttcattt gggaagaatt tgccaactgg tatgttgagt
     6361 tgaccaagga agttctttac agcgacaatg aagacgataa ggtaattact cgatctgttc
     6421 tcctctatac gctggataaa atccttcgtc tccttcactc aataatgccg ttcgtgacag
     6481 aagaaatctt tggtcagtac gctgaaggct ctatcgtgac agcagcatac ccaactgtca
     6541 acccagtctt tgaggacctt gctgcccaca ctggtgtgga aagtctcaaa gacttgatcc
     6601 gtgccgttcg taatgcgcgt gcggaagtaa atgtagcacc aagcaaacct atcacaatcc
     6661 ttgttaagac tagcgatagt gacttggaag ccttctttaa cagcaatgtc aactacatca
     6721 aacgctttac aaatccagaa cacttggaaa tcgcatcaac catccctgca cctgaactgg
     6781 ctatgtcaag cgttattaca ggagccgaaa tcttcttgcc actggtagac ctcttgaatg
     6841 tcgaagaaga attggcacgt ctggaaaaag aacttgccaa atggcagaaa gaactcgaca
     6901 tggttggcaa aaaactcagc aacgaacgct tcgtcgccaa cgctaaacca gaagttgtcc
     6961 aaaaagaaaa agacaaacaa gccgactacc aagccaagta tgatgtgacc gtagcacgta
     7021 ttgatgagat gaagaagttg gtgaaataaa cacagaaaca cggtgatgag ccgtgttttt
     7081 tggtataatg aaatcaatat ctattgatgg agaaagtgat gtccaaacac cctcattatg
     7141 aattgttaaa tttaattggc tacggtcttg ccaagtttga caagcttttt ataaaagaat
     7201 ttcaatgctc tagcaagtcg gagttttatc gctatgtggt ttctctggga attgctgaaa
     7261 caactggagt tgtaaaaaat agaatggatt tatttgatcc ttattttgac aataatcgaa
     7321 aaggttggtg gcagaaagct gaagtttatc gttttcgtaa agatttaatt gatatgatgt
     7381 ttggaaatga agatgttcat agttatgctg aaatagttaa aatgttactt gccagtgaag
     7441 ggaagaaaac aggcataacc atcgttgaaa aaccaatagt tcgaactaaa ttcaaacgtc
     7501 tacaggaaac gggaatggag gctgagaatt attttatcct tcattttgat aaagaagaaa
     7561 aattccaagg tggacagtta accgatgccc gtctttatgg tgatggatat gactttcagg
     7621 tagatgtcca agagtattct taccttgccg aagtaaaagg tatccgaaaa tctaaggggc
     7681 gtgtgcgttt aactgcaaaa gaatttgaaa aagtcaagga gtttcaatcg gattttattt
     7741 tatccttggt cacaaatcta gatgatattc caaagttagt gttaatcgat aatcctttaa
     7801 aacattttga gtttaaaaag aatattatca aaaatgaaat cattgaatat agaagcgtag
     7861 aggatttgta ttagttcccc cttaactttt ccagttgaag gaacgagaag tcttgacagg
     7921 tcaacgactt aatgaactgg aaatcaacgg tattcgtttg actaagtttt aagatggcga
     7981 aatcggtatt gaatttatca gtagtgctga ttataactct tttat
//
LOCUS       DAVLHB010000067         7464 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLHB010000067 DAVLHB010000000
VERSION     DAVLHB010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.067"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..379
                     /locus_tag="VXE36_001917"
     CDS             <1..379
                     /locus_tag="VXE36_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0780156.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEEMMTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEALLSCSCFN"
     gene            465..1415
                     /locus_tag="VXE36_001918"
     CDS             465..1415
                     /locus_tag="VXE36_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0780157.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVFSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1592..2599
                     /gene="gap"
                     /locus_tag="VXE36_001919"
     CDS             1592..2599
                     /gene="gap"
                     /locus_tag="VXE36_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0780158.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2666..3502)
                     /locus_tag="VXE36_001920"
     CDS             complement(2666..3502)
                     /locus_tag="VXE36_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0780159.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3628..5823
                     /locus_tag="VXE36_001921"
     CDS             3628..5823
                     /locus_tag="VXE36_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0780160.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQVVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5876..6028
                     /gene="rpmG"
                     /locus_tag="VXE36_001922"
     CDS             5876..6028
                     /gene="rpmG"
                     /locus_tag="VXE36_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0780161.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6038..6214
                     /gene="secE"
                     /locus_tag="VXE36_001923"
     CDS             6038..6214
                     /gene="secE"
                     /locus_tag="VXE36_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0780162.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6269..6805
                     /gene="nusG"
                     /locus_tag="VXE36_001924"
     CDS             6269..6805
                     /gene="nusG"
                     /locus_tag="VXE36_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0780163.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6927..7406
                     /locus_tag="VXE36_001925"
     CDS             6927..7406
                     /locus_tag="VXE36_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0780164.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT         2362 a         1278 c         1632 g         2192 t
ORIGIN      
        1 aagaggtaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
       61 tggtgagtta atcgctccaa tgacttacga agagatgatg acgagcgact tttttgaagc
      121 ttggtttcag aagtttctct taccaacatt aaccacacca tcggttatta ttatggataa
      181 tgcaagattc catagaatgg gtaagttaga acttttatgc gaggagtttg ggcataaact
      241 tttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      301 caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc ttttatgagg ctcttttgtc
      361 ctgctcttgt ttcaattgac tatagttcac ggatacagtt gggaaagaag ctattaaata
      421 tttggagagt ccttttggga tgaacatgtc aaatattact atagatgggc aagaaaagat
      481 gggcaagaaa tggatctgag tcaaacgatg cttcttatgc tcaagtagtg agtctttatg
      541 atgatacaag tatctctgtt agtaataatg agacggacaa agtgttgact ggatccctct
      601 atactgaaac aaatgaacag ggattaacga ttccaagcag tttactaaaa aattggaatg
      661 aacagacagg aaaaaatttg acaactaatg atcttattgg caaatcagtc tcagccagca
      721 ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt tcaaacgaag attgtacgtg
      781 taatcaatga tgaagatgac atggaggaca gcaacagttt catgctgtct catcaaatgg
      841 aaacgatttt gaaagaggct ggatttacga aagctgtatc ttattttatc ttggaactca
      901 aagatccatc acagacaaaa gtagtaacag aagaattaca gaaaaataag aagtatactg
      961 tgttttctca acagagagtt cttgatattg tgattacctt tattcgtgtt attcagggat
     1021 tattgattgt gctttcatca caagctattg tggtagcagc ggttatgatt ggtatcatta
     1081 tttacatcaa tatcatgcaa cgttccaagg aaataggtgt catgaaagca gttggttatc
     1141 agaatcgtgg tgtcaaagga atttttattt acgaggctat ctggattgta ggcatcgcct
     1201 tgctgctggc atttttggtt gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc
     1261 acttttaccc atccatcact aaggtttttg aattaaatct tttatctgtt ttaggaactc
     1321 tagttttcgc tctattactt ggttatgtct cagcctactt cccggcgcgt aagattagta
     1381 aaatggatcc tgtagaatcg ttacgctatg aataataagg gattccttga tttacagtct
     1441 taaaaagaaa ctcacataga aaaacaatgg ccatacttgc aattcaactc aaatagttgt
     1501 ataataggtt tgttgaaagg tgatttgtag tgattcaagt tactcttttc acaataaaaa
     1561 tttcatgatt ttcataagga ggaaatcact aatggtagtt aaagttggta ttaacggttt
     1621 cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac
     1681 acgcatcaac gaccttacag atccagttat gcttgcacac ttgttgaaat acgacacaac
     1741 tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt ggattcgaag ttaacggtaa
     1801 attcgttaaa gtttctgctg aacgtgatcc agagcaaatc gactgggcta ctgacggtgt
     1861 agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa gaagcagctg aaaaacacct
     1921 taaaggtgga gctaaaaaag ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt
     1981 tgtattcaac actaaccacg acgttcttga cggtactgaa acagttatct caggtgcttc
     2041 atgtactaca aactgcttgg ctccaatggc taaagctctt caagataact ttggtgttgt
     2101 tgaaggattg atgactacta tccacgctta cactggtgac caaatgatcc ttgacggacc
     2161 acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc
     2221 aactggtgct gctaaagcta tcggtcttgt aatcccagaa ttgaacggta aacttgacgg
     2281 atctgcacaa cgcgttccaa ctccaactgg atcagttact gaattggtag cagttcttga
     2341 aaagaacgtt actgttgatg aagtgaacgc agctatgaaa gcagcttcaa acgaatcata
     2401 cggttacaca gaagatccaa tcgtatcttc agatatcgta ggtatgtctt acggttcatt
     2461 gtttgacgca actcaaacta aagttcttga cgttgacggt aaacaattgg ttaaagttgt
     2521 atcatggtac gacaacgaaa tgtcatacac tgcacaactt gttcgtactc ttgaatactt
     2581 cgcaaaaatt gctaaataat tcttgagttg atagaaagca aggctttgtg gtcttgcttt
     2641 ttatatggaa aaatggatga cacgatcatc cattcttttt taattctttt tcaaatgtat
     2701 ttgaaagggt agtgaaagtt agcttctcta aagtaagtgg gtgggtaaag gaaagtcgga
     2761 aggcatgaag cataagccga cttgtctttg atttactatt atagagaggg tcgcccagga
     2821 taggaagatt atgatgcgaa aggtgcacac gaatctgatg ggttcgccct gtctttagct
     2881 tgcaacgagc caaggaagtc ttgtttgaga attgctttaa cctgcttaca tgcgtttcag
     2941 catattgccc attttttgca tcaactattc tttttctacg atcatggcga tcacgtccaa
     3001 ttttgtctct gaaaacaagt tcttttctgt tgatatttcc atcaactaga gcccaatatt
     3061 ctctagaaat ctcttttttc tccaataagc gattgagaat gggcaggata aaaggatttt
     3121 tggcaaagag aactaagcca ctggtttcca tgtccagacg atgaacgaca tagcaggttt
     3181 ggccaacata ggtactgaca tggttaagaa gggcaatttc gtttggttga ttaccatgcg
     3241 ttttcatccc ctctggtttg tttacaataa tcaagtgttg atcttgataa acttcctgca
     3301 ctaagtctgg gttgccccaa gggatcgtct tttgggaata atcttcctcg tcaaaagtca
     3361 actggcaaac atctccagga tttacgattt cgttccagtg gacttcttct tgatttatca
     3421 aaatatgttt cttgattctc aaaaaatgac ggatttttct agggatgagg agttgttcct
     3481 caagtaattg ctttaccgtc atttgaggta gagaggcggg taatgtaaat gtgaattgca
     3541 tacagatatt gtaacaaaaa aagccctatt tggataggaa atagctaaat tcttgtcttc
     3601 ctatgatgaa gatgataaaa taaacgcatg aaattagata aattatttga gaaatttctt
     3661 tctcttttta aaaaagaaac aagtgaacta gaggactctg attctactat cttacgtcgc
     3721 tctcgtagtg atcgaaaaaa attagcccaa gtaggtccga ttcgaaaatt ctggcgtcgt
     3781 tatcatctaa caaagattat ccttatacta ggtttgagtg caggcttgct agttggaatc
     3841 tatttgtttg ctgtagccaa gtcaaccaat gtcaatgatt tgcaaaatgc cttgaaaact
     3901 cgaactctta tttttgaccg tgaagaaaaa gaggctggtg ccttgtctgg tcaaaaggga
     3961 acctatgttg agctgactga catcagtaaa aacttgcaga atgctgttat tgcgacagaa
     4021 gaccgttctt tctataaaaa tgacgggatt aactatggcc gtttcttctt ggctattgtc
     4081 actgctggcc gttcaggtgg tggctctacc attacccaac agctggctaa aaacgcctat
     4141 ttatcgcagg atcaaactgt tgagagaaaa gcgaaagaat ttttccttgc cttagaatta
     4201 agcaaaaaat atagtaagga gcaaattcta accatgtacc ttaacaacgc ttattttgga
     4261 aatggtgtgt ggggtgtaga agatgcgagt aagaaatact ttggagtttc tgcatcagaa
     4321 gtgagtctgg atcaagctgc gactctggca gggatgctca aggggccgga actgtataat
     4381 cccttgaatt ccgtagaaga ttctactaat cggcgcgata ctgtcttgca gaatatggtt
     4441 gcagcaggat atattgataa aaaccaagaa accgaagctg ctgaagttga tatggcttcg
     4501 caattgcacg ataagtatga aggaaaaatc tcagattacc gttacccctc ttattttgat
     4561 gcggtggtta atgaagctgt ttccaagtat aatctaacag aggaagagat tgtcaataat
     4621 ggctaccgca tttacacaga gctggaccaa aactaccaag caaatatgca ggttgtttat
     4681 gaaaacacat cgctatttcc gagggcagag gatggaacgt ttgctcaatc aggaagtgta
     4741 gctctcgaac cgaaaacagg gggagttcgt ggagttgtcg gtcaagttgc tgacaatgat
     4801 aaaactggat tccggaattt caactatgca acccaatcaa agcgtagtcc tggttctaca
     4861 attaagcctt tagttgttta tacgccagca gttgaagcag gctgggcttt gaataagcag
     4921 ttggataacc ataccatgca gtatgacagc tataaggttg ataactatgc agggatcaaa
     4981 acgagtcgag aagttcctat gtatcaagcc ttggcagaat cgcttaatct acctgctgtt
     5041 gccactgtta atgatttggg tgtcgacaag gcttttgagg caggcgaaaa attcggactc
     5101 aacatggaaa aggtcgaccg tgttcttggt gtcgccttgg gaagcggtgt tgaaaccaac
     5161 cctcttcaaa tggctcaagc atacgccgcc tttgcaaatg aaggtttaat gcctgaagct
     5221 cattttatta gtagaattga aaatgctagt ggacaagtta ttgcgagtca taaaaattca
     5281 caaaaacggg tgattgataa gtctgtagct gacaagatga ccagtatgat gttggggact
     5341 ttcaccaacg gtaccggtat tagttcatcg cctgcagact atgtcatggc agggaaaact
     5401 ggaacaactg aagcagtttt caatccggag tacacaagtg accagtgggt aattggttat
     5461 actccggatg tagtgattag ccactggctt ggctttccga ccactgatga aaaccattat
     5521 ctagctggct ctacttcaaa cggtgcagct catgtcttta gaaacattgc caataccatt
     5581 ttaccttata cgccaggaag tacctttacg gttgaaaatg cttataagca aaatggaatt
     5641 gcaccagcca atacaaaaag acaagtacaa accaatgata atagccagac agatgataat
     5701 ttgtctgata ttcgagggcg tgcgcaaagt ctagtagatg aggctagccg ggctatctca
     5761 gatgcgaaga ttaaggaaaa ggctcaaaca atatgggatt cgatagtcaa tctatttcgc
     5821 taagatgctt gtcaaagcct agctttcttg ttataatgga taagatggag gcgttatggc
     5881 actaaaaaaa gcaagcctag cttgtgcggt ttgtggttcg agaaactatt caatcaagat
     5941 cagcggaaac cccaagccta cacgactaga agtaaataaa ttttgtaagc attgtggcaa
     6001 gtacactaca cacagagaaa cgagatagga gagagcgatg cgttttattg gagatatttt
     6061 tagacttctt aaagacacaa catggccaac tcgcaaggaa agctggagag attttcgttc
     6121 tatcatggaa tacacagctt tctttgtagt aattatttac atttttgacc agttgattgt
     6181 ttcaggtttg attcgattta ttaacatttt ttagaagatt agtggagtta attacactag
     6241 aaatcttcta tttatgaaag gaaatatcat ggatagtttt gataaagggt ggtttgtttt
     6301 acaaacttat tctggttatg aaaataaggt gaaagaaaat ctattacaac gtgcacaaac
     6361 ctacaatatg ttggataata ttctacgcgt tgaaattcca acacaaacag tgcaagttga
     6421 aaaaaatgga aagagaaaag aagtagaaga aaatcgcttt ccaggttatg ttcttgtaga
     6481 aatggtcatg acagatgaag cttggtttgt tgttcgaaac acaccaaatg ttacaggatt
     6541 tgtcggatca cacgggaaca gatcaaaacc aactccatta ttggaacaag aaattcgcga
     6601 cattttggta tctatgggac aaactgttca agaatttgat ttcgatgttg agattggtca
     6661 aactgtacgt attattgatg gtgcttttgc agactacact ggtaagatta cagaaattga
     6721 taataacaaa gtgaaaatga ttatctctat gtttggtaat gacacagttg cagaagtaaa
     6781 tctaaaccaa atcgcagaat tataaccctg agagaggctg gagcttctct tttttgtgca
     6841 gtttaggagc taaagggaac agaatggaga aaatggaaca aatgtgtttt ctaatctgtt
     6901 agactgtatc tagaaagggg aaaattatga ttaaagaatt gtatgaagaa gtccaaggga
     6961 ctgtgtataa gtgtagaaat gaatattacc ttcatttatg ggaattgtcg gattgggacc
     7021 aagaaggcat gctctgctta catgaattga ttagtagaga agaaggactg gtagacgata
     7081 ttccacgttt aaggaaatat ttcaaaacca agtttcgaaa tcgaatttta gactatatcc
     7141 gtaagcagga aagtcagaag cgtagatacg ataaagaacc ctatgaagaa gtgggtgaga
     7201 tcagtcatcg tataagtgag gggggtctct ggctagatga ttattatctc tttcatgaaa
     7261 cactaagaga ttatagaaac aaacaaagta aagagaaaca agaagaacta gaacgcgtct
     7321 taagcaatga acgatttcga gggcgtcaaa gagtattaag agacttacgc attgtgttta
     7381 aggagtttac tatccgtacc cactagtaag tcatgcaaaa aaaatgaaaa aaattagaaa
     7441 aagtagttga caaagtttga aaag
//
LOCUS       DAVLHB010000068         7448 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLHB010000068 DAVLHB010000000
VERSION     DAVLHB010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.068"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            120..275
                     /locus_tag="VXE36_001926"
                     /pseudo
     CDS             120..275
                     /locus_tag="VXE36_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            475..3750
                     /gene="rexB"
                     /locus_tag="VXE36_001927"
     CDS             475..3750
                     /gene="rexB"
                     /locus_tag="VXE36_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0780165.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3747..7397
                     /gene="addA"
                     /locus_tag="VXE36_001928"
     CDS             3747..7397
                     /gene="addA"
                     /locus_tag="VXE36_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0780166.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSFQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2264 a         1574 c         1589 g         2021 t
ORIGIN      
        1 gattgaaata agatacgaac agcttgatta gggaaatcaa attaatttct agaaatattt
       61 tagcatccac gatgtactat tatagtttca atttactata gttcaatcat tctatcaaga
      121 atattgaata tataaaggca cgtaatatta aaacttcttc tgatatcgaa ttagagtccg
      181 atgttgatgg cgataaatca gacaatctac ccgtcgacat taagatactg ggacaacaca
      241 ttgaagtgta ttccgtacct aagaaacaat cataaaactc aaagtcttgc taccgaggct
      301 tttttattat gtgattttca gtagccagac ttattctatc taatacaagt aaagctaagt
      361 atttaagatt tagcagatga tgaagaaaag aaaggatggc ctaaatattt taacagattt
      421 acgaggctaa tcatggtata atatagggtg atgaaaaatt ccaacgaggc tgagatgaaa
      481 ttactttata ctgatattcg aacttctttg acagaaattc taacaagaga ggcagaagag
      541 ctagttgcag ctggcaagcg ggtcttctac attgccccca actctctttc ttttgaaaag
      601 gaacgcgccg tgctggaatg cttgtcccag caggcttctt tttcgattac cgtcacgcgc
      661 tttgctcaaa tggctcgtta tctggtcttg aatgatttac cagttaaaac tactcttgat
      721 gatatcggtc ttgggttggc cttttacaaa tgccttgccg aactcgatcc caaggacttg
      781 cgtgtttatg gcgctattaa gcaggatcct caattgatcc agcagttaat tgagctttac
      841 catgagatga ccaaatctca gatgagtttt ttggacttgg agaatttaac agatgaggat
      901 aagagggcgg atttactctt gatttttgag aaagtaacag cctatcttaa tcaaggtcag
      961 ttagcccagg gaagtcagtt gtcccatttg attgaggcta ttgagaatga caaggtaagt
     1021 agtgatttta atcaaatcac cttggtcatt gacggcttta ctcgtttttc tgctgaggaa
     1081 gagcgggttg tggacttact tcacggcaaa ggtgttgaga ttgttatcgg ggcttatgct
     1141 agtaagaaag cctataccag tccttttagc gagggcaatc tctaccaagc cagcgtaaaa
     1201 tttctccatc atctggcttc taaataccaa acgcctgctc aggactgttc tcaaactcat
     1261 gagaagatgg atagttttga caaggcctct cgtttgttgg agtcttctta tgacttttca
     1321 gaactcgctt tggatgtcga tgagaaagac cgtgaaaatt tacaaatctg gtcttgtttg
     1381 acgcaaaagg aggagttgga gctagtagcc cgtagtattc gtcagaaatt acatgagaac
     1441 tcagacctga gctacaagca ttttcgtatt ctcttggggg atgtagcttc ttaccagtta
     1501 tctctcaaaa ccatttttga ccagtatcag attccttttt atcttggtag aagcgaagcc
     1561 atggctcatc atcccttgac tcagtttgtc gagtctattt tagctttaaa acgttaccgt
     1621 tttcgtcagg aggatttgat caatcttctt agaactgact tgtatactga cctcagtcag
     1681 tctgatattg atgcttttga gcaatatatc cgctatcttg gtatcaatgg cttgccagcc
     1741 tttcagcaaa ccttcaccaa atcccaccat ggaaaattta atcttgagcg tttgaatgtc
     1801 ctccgcctga gaattttagc acctcttgaa accctctttg ccagccgaaa acaaaaggct
     1861 gaaaacctcc tacaaaaatg gagtgtcttt ctaaaagaag gagctgtgac caagcagtta
     1921 caagatttga caaccacttt ggaagctgta gaacaggaaa gacaagccga agtttggaag
     1981 gctttctgcc atgttttaga acaatttgcg actgtttttg ctggttcaca ggttagtctg
     2041 gaagacttcc tagccttgct ccattctgga atgagtttgt cccaataccg taccattcca
     2101 gcaacagtgg acactgttct ggtgcagagt tacgatttga ttgcaccatt gactgctgac
     2161 tttgtctatg ctattggact aactcaggac aatttaccaa aaatttctca aaacaccagt
     2221 cttctgacag atgaagaaag gcaaaaccta aaccaagcga ccgaagaagg cgttcaatta
     2281 ctgattgcca gcagtgaaaa tctcaagaaa aatcgctaca ctatgctttc cttggtcaat
     2341 tctgctcgta agcagttgtt cttgtcggct ccaagccttt ttaacgaaag tgaaagtaag
     2401 gaatctgcct atcttcaaga gttgatccat tttggattta ggcggagaga gaagaggatg
     2461 aatcacaaag gactgtctaa ggaggatatg gggtcctatc acagtctttt gtctagtctg
     2521 gttgcctatc accagcaggg tgagatgagc gatactgagc aagatttgac ttttgtcaag
     2581 gttctgtcgc gtgtcatagg taaaaaacta gatcagcaag gtctggaaaa tccagctatc
     2641 ccaaccagtc caagcagcaa gaccttagcc aaggacacct tgcaagctct ctatcctgcc
     2701 aaacaggagt tttacctgtc tacgtcgggt ttgacagagt tttatcgcaa tgaatacagt
     2761 tatttcctac gctacgtttt aggcttgcag gaggaattac gtttgcatcc tgatgcccgt
     2821 agtcacggga atttcttgca tcgtatcttt gaacgcgcct tacagttgcc taatgaagat
     2881 tcctttgacc aacgtttaga acaagctatt caagaaacca gtcaagaacg cgaatttgaa
     2941 gctatttatc aagaaagttt ggaagcccag tttaccaagg aagttttgct tgatgttgca
     3001 cggacgactg gacatattct ccgacacaat ccagccatcg aaaccatcaa agaagaagca
     3061 aattttggtg gaaaagacca agcctttatt caattagaca atggacgcag tgtctttgta
     3121 cgaggcaagg tggaccggat tgaccgtttg aaagctaatg gagcgatagg agtagtagac
     3181 tacaaatcca gtctgactca gttccagttt cctcatttct ttaatgggct caattctcag
     3241 ttaccaacct atcttgctgc cctaaaaaga gaaggggagc agaacttttt cggcgccatg
     3301 tacttggaaa tggctgaacc tgtccaatct ctgatggcgg taaaaagtct ggcgggtgca
     3361 gtagtagaag ccagcaagtc aatgaaatac caagggctct tcttggaaaa agaaagcagt
     3421 tatttaggcg aattttataa caaaaacaag gctaatcaac tgacagatga ggaatttcag
     3481 ctcctactgg actacaatgc ctatctttac aagaaagctg ctgagaagat tttagcaggc
     3541 cggttcgcca tcaatcctta tactgaaaat ggcagaagca ttgccccata cgtccagcaa
     3601 catcaggcta ttacaggctt tgaagccaat taccatctgg gccaagcccg tttcctagaa
     3661 aagttggacc tagctgatgg caagcgtctg gtcggagaaa aactcaagca agcttggctt
     3721 gaaaaaataa gagaggagtt gaatcgatga agcttattcc ctttttaagt gaggaggaga
     3781 ttcaaaaact gcaagaagca gaagcaaatt cgagcaagga acagaagaaa actgccgagc
     3841 aaatcgaagc tatctacact tctggccaga atatcctggt ctcagcatcg gctggttctg
     3901 gaaagacctt tgtcatggca gagcgcattc tggaccaatt ggcgcgtggt gtcgaaattt
     3961 ctcaactctt tatctcaacc tttacggtca aggctgcaac tgaacttaaa gaacgtttag
     4021 agaaaaaaat cagcaagaaa atccaagaaa cagatgatgt cgacctcaaa caacacttgg
     4081 gacgccagtt ggcagaccta cccaacgctg ccatcggaac catggactct ttcacacaaa
     4141 aattccttgg caaacatggt tatctgcttg atattgcacc taatttccgt attttacaaa
     4201 atcaaagcga gcaacttctt ctcgaaaacg aagtctttca tgaggtcttt gaagcccatt
     4261 accaaggtaa acagaaagag acctttagtc atttgctgaa aaactttgct gggcgtggca
     4321 aggacgaacg gggtctgcgc cagcaagtct ataaaattta tgacttcctc caatccacca
     4381 gtaatcctca aaagtggctg agtgaatctt tcctcaaagg ttttgagaaa gctgatttta
     4441 ccagtgaaaa agaaaaactg actgagcaaa tcaaacaagc cctttgggat ttggaaagct
     4501 ttttccgtta ccatctggat aacgatgcca aggagtttgc aaaggctgcc tatttagaaa
     4561 atgttcagtt aattctggat gaaattggct ccctaaatca ggagttcgat agtcaggctt
     4621 atcaggcagt acttgcgcgt gttgtcgcca tctctaagga gaaaaacggt cgtgctctga
     4681 ctaatgccag ccgtaaggct gatttgaagc ccctggctga tgcctacaac gaagagagaa
     4741 agacccagtt tactaaacta ggacaattat cagaccagat agcgattctc gactatcaag
     4801 aacgttatca tggagacact tggaaactag ctaaaacctt ccaatctttc atgagcgatt
     4861 ttgtagaggc ttatcgtcag agaaaacgac aggaaaatgc ctttgaattc gctgatatca
     4921 gccattacac cattgagatt ttagaaaatt tcccacaagt tcgtgagtct tatcaggagc
     4981 gcttccatga agtcatggtc gatgagtatc aggataccaa ccatattcaa gaacggatgc
     5041 tggaattgtt gtctaatggc cacaatcgct ttatggtggg agatatcaag caatccatct
     5101 atcgtttccg tcaggcagac ccgcagattt tcaatgagaa attccaacgc tatgcgcaaa
     5161 atcctcaaga aggcaagctc attctcctca aggaaaattt ccgtagtagt tcagaagtgc
     5221 tgtcagcaac caatgatgtc tttgaacgtc tcatggacca agaggtcggc gaaatcaact
     5281 atgataacat gcaccagctt gtttttgcca ataccaaact gactcccaat ccagacaaca
     5341 aggctgaatt tctcctctac gacaaggacg atacaggtga ggaagaagag agtcaaacag
     5401 aaacgaaact aacaggcgaa atgcgcttag ttatcaagga gattctgaaa cttcatcaag
     5461 aaaaaggtgt tgcctttaag gaaattgccc ttctgacctc cagccgcagt cgtaatgacc
     5521 agattctcct cgccctgtct gagtacggga ttcctgtcaa aactgacgga gagcaaaaca
     5581 attatctcca atccctagaa gtgcaagtca tgctagacac tcttcgtgtc attcacaatc
     5641 ccctgcaaga ctacgccttg gttgccctta tgaagtctcc aatgtttggt tttgatgagg
     5701 atgagctagc acgtttgtcc cttcagaaag cagaggataa agtccacgaa aatctctatg
     5761 agaaactggt caatgcacaa aaaatggcaa gtagtcaaaa aggcttgatt cacacagctc
     5821 tagctgaaaa actaaagcaa ttcatggata tcctagcttc ttggcgcttg tatgccaaac
     5881 cccactctct ctatgacttg atttggaaga tttacaacga ccgtttttat tatgactatg
     5941 ttggggcttt gccgaatggt cctgctaggc aggccaatct ctatgcccta gcactgcgtg
     6001 ctgatcaatt tgaaaagagc aatttcaaag gtttgtcgcg ttttattcgt atgattgacc
     6061 aagtcttaga agcccagcac gatttggcaa gcgtggccgt cgcaccgcca aaagatgcag
     6121 tagagctcat gaccatccac aagagtaaag ggctggagtt tccttacgtc tttatcctca
     6181 atatggatca agatttcaac aagcaagact ctatgtcaga agtcattctc agtcgtcaga
     6241 atggtcttgg tgtcaaatat attgccaaga tggagacagg ggcagtagaa gaccactatc
     6301 ctaaaaccat caaactctcc attcctagtc tgacctatag gcagaacgaa gaggaattac
     6361 agctagcaag ctattctgag cagatgcgtt tgctgtatgt tgctatgacg cgggctgaga
     6421 aaaagctcta tcttgtcggc aagggttctc gtgaaaagct ggaatccaag gaatacccag
     6481 cagccaaaaa tgggaaacta aatagcaata ctagactgca agcacggaat ttccaagatt
     6541 ggctttgggc tatcagtaaa gtgtttacta aggacaagct caactttagt tatcgtttta
     6601 ttggcgaaga tcagttgacc agagaagcta tcggagagtt ggaaaccaag agtcctctcc
     6661 aagatagctt ccaagcagac aatcgtcagt cagataccat caaagaagct ctggaaatgc
     6721 tgaaggaggt ggaagtttat aatactcttc accgcgcagc tattgaactt cctagtgttc
     6781 aaaccccaag tcaaatcaag aaattttacg aaccagttat ggatatggaa ggtgtcgaga
     6841 ttgctggtca aggtcagtca gtaggcaaga aaatcagctt cgatttgcca gatttttcaa
     6901 ccaaagaaaa ggtaactgga gctgagattg gtagtgctac tcacgaactc atgcagagaa
     6961 ttgacctcag ccagcaacta acccttgcta gcctaacaga aacactcaaa caagttcaaa
     7021 ctagccaagc tgtcagagac aagatcaatc ttgataaaat tcttgctttc tttgacacag
     7081 cactcggtca ggaaattctt gctaataccg accatctcta tcgcgagcaa cctttctcca
     7141 tgctcaaacg agaccaaaag agtcaggaag actttgttgt ccgtggtatc cttgatggct
     7201 atctgcttta cgaaaacaaa attgttctgt tcgactacaa gacagaccgc tatgatgaac
     7261 caagtcaact cgtagaccgc tatcgtggtc agttagctct atacgaagag gctttatcac
     7321 gagcctattc gattgaaaat attgaaaaat acttgatttt actcggtaaa gacgaggttc
     7381 aagttgtaaa agtataactt atactcttcg aaaatctctt caaaccacgt cagcttcgcc
     7441 ttgctgta
//
LOCUS       DAVLHB010000069         7244 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLHB010000069 DAVLHB010000000
VERSION     DAVLHB010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7244
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.069"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            157..684
                     /locus_tag="VXE36_001929"
     CDS             157..684
                     /locus_tag="VXE36_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0780167.1"
                     /translation="MEDYCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNT
                     RKAQGRHLEQEGNIKHALIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQ
                     TLMESLSDDDYDFAFDEALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKY
                     ECYSPLNNLELDDFE"
     gene            complement(850..921)
                     /locus_tag="VXE36_001930"
     tRNA            complement(850..921)
                     /locus_tag="VXE36_001930"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(886..888),aa:Arg,seq:cct)
     gene            complement(963..1310)
                     /gene="rplS"
                     /locus_tag="VXE36_001931"
     CDS             complement(963..1310)
                     /gene="rplS"
                     /locus_tag="VXE36_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0780168.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1429..1758)
                     /gene="crcB"
                     /locus_tag="VXE36_001932"
     CDS             complement(1429..1758)
                     /gene="crcB"
                     /locus_tag="VXE36_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0780169.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1752..2126)
                     /gene="crcB"
                     /locus_tag="VXE36_001933"
     CDS             complement(1752..2126)
                     /gene="crcB"
                     /locus_tag="VXE36_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0780170.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(2123..2389)
                     /locus_tag="VXE36_001934"
     CDS             complement(2123..2389)
                     /locus_tag="VXE36_001934"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0780171.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2505..2948)
                     /locus_tag="VXE36_001935"
     CDS             complement(2505..2948)
                     /locus_tag="VXE36_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0780172.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            3052..3987
                     /locus_tag="VXE36_001936"
     CDS             3052..3987
                     /locus_tag="VXE36_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0780173.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4041..4325
                     /locus_tag="VXE36_001937"
     CDS             4041..4325
                     /locus_tag="VXE36_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0780174.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4382..4600)
                     /locus_tag="VXE36_001938"
     CDS             complement(4382..4600)
                     /locus_tag="VXE36_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780175.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(4597..5348)
                     /locus_tag="VXE36_001939"
                     /pseudo
     CDS             complement(4597..5348)
                     /locus_tag="VXE36_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5685..7031
                     /gene="gdhA"
                     /locus_tag="VXE36_001940"
     CDS             5685..7031
                     /gene="gdhA"
                     /locus_tag="VXE36_001940"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0780176.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT         2309 a         1451 c         1287 g         2197 t
ORIGIN      
        1 tctggaaaaa aagcagaatt aattacaaga ataattaata atgttaacat tgacaattta
       61 gatattccgt tcgaatttaa actaacaaaa gaagcacaaa atcttattat cgaacatagt
      121 gactatatca aagcatacta tgataaagac ataactatgg aagattattg taaagaaaaa
      181 aacaatatct cttttaaagc aacttttggt gatataaaat ggagtctctt aaataaacaa
      241 gctcatagga atactgtatc aggagatttt ggatgcttat ctaacacacg aaaggctcag
      301 ggaagacatt tggaacaaga aggtaatatt aaacatgctt taatatatta catagaatct
      361 ttgataatta ctatttcagg attagaaaac aatttttcag ccactgatta tccagtatat
      421 tatcccgatt cgatacctga ctactcacta aaacatattc aaacattaat ggaatcatta
      481 tctgatgacg attatgattt tgcttttgat gaagcattat ttcgcttctc aattttgaat
      541 gcaaatcatt ttttatctaa ggaagatatt gactatttaa gagttaattt acctcgttcc
      601 actgctgaag aaataaacaa ttacttaaag aaatatgaat gttatagtcc tttaaataat
      661 ttagaacttg acgattttga ataaattgac tatacaaaca tttatatact cgatatagtc
      721 tcaattttat ctgatgattg cccaaatttt tcaataataa aacgcataat attatggaga
      781 caatccccta tattatgcgt tcttttaata tcaaagactt tttgacaaac ttcttcgata
      841 tctaattact gccccctgca ggaatcgaac ctgcaactac tccttaggag ggagttgtta
      901 tatccattga actaagggag ctagataaaa actctgctga aaagcagagt tttttagtcg
      961 aattaacgac ggatttcttt gatacgagct gccttacctt gaagagcacg caagtagtac
     1021 aatttcgcac gacgtacttt accgtaacga acaacttcga ttttttcaac acgtggagtg
     1081 tggattggga agatacgctc aacacctaca ccgttagaga ttttacgaac tgtgtagttt
     1141 tctgagattc cagcaccttt acgtgcgata acaacacctt caaaaatctg gatacgttca
     1201 cggttacctt cgacaacttt cgcatgtaca cgaacagtgt caccaggacg gaatgatggg
     1261 atatctgtac gaagttgacc ttcagtcaag ctttggatta atggattcat tttattctcc
     1321 tatctttgtc aatcttgagg aatcttcctc agcggataaa ctgtattttt gtgcgtccat
     1381 tacacacaag atatagttta ccaaatttct aaaaaaaagt aaagaaattt atagcaaaat
     1441 tcctaaaaaa atcgcaacca aaccacctat gtaagtcaaa gtcaggtaag aataaaagac
     1501 cttcttatca cttagcagtc tttgaagttc gtcattcaag gtcgaaaaag ttgttaaacc
     1561 gccacaaaat cctgttgcta gaatagcata tacttcctta gactctacat gattgtagaa
     1621 tactccaatt aaaaaacaac ctaaaagatt agctatgagc gttccgagtg gcaatttaga
     1681 agcttgatta tagcgagaaa agaaataccg tacgagtgct cccaagccac aggcgattgc
     1741 aagatagacg attaccattt cttcctcccc aaatagtaag ctaaaagcag gcctccaccg
     1801 atactcaaaa gcaaatacag tatcaaacta agataacgcc ctgtatcaag cagcttcaca
     1861 gtatcaagca ttaggctgga aaaagttgtt aaacctccgc aaaaacccgt ccccagtgct
     1921 aaaatcaagc ccttactagt ccccttatag accagatagc ccttgacaag ataaatcaag
     1981 cagaaaattc ccagatagtt gacaaagaga gtgccccaag ggaaatctgg actggctggt
     2041 aaccaagtgg aaactaggta gcggacaagt ccgcccaaca tagcagctag aaaaatccct
     2101 agcggataaa attgttcttt tttcatttga tattttgatc ctgataatca cgcgaacgtt
     2161 tgagtatgtc cgaaaaagtc gcgacaatag tctcctgata gcgcttgtcc tctacacgac
     2221 ttctaacctt ttcaaaaata actgcttctc tcttagtatc taaaatcggt ttccctgaag
     2281 ccttcttata agcgacaact ccttcaacta agtgcattcg ttcttctaac agtttgacaa
     2341 tttggtcgtc gatttgatcg atttcttgac gaataatatc taaatccata cagtctcctc
     2401 ctttatttga attattgtat caaaaagcca tcaattaggc tagtaaaatc ccaactctcg
     2461 ataagaaaaa tgcactgatt gattacatca gcgcactttt atgcttatcc tactttagca
     2521 gccaattctt ctgcgaattg ttccaagcgt tcaatatctt cttcctcggc agaaagatca
     2581 actttaacac actctgaacc tttttctgct cctgttgaca caaagacacg gtcaaagtca
     2641 tcaacagcct tacaaaattc atcgtagaag gtatctcctg agccgaccac tccgtagatt
     2701 ttgccattca agttgagatc tgctaggtct tcgtagaagt ccatcatctc atctggcaat
     2761 tcaccatcac cataagtata ggtcgcaacg atagcgatgt ctgcttccaa gaagtctgaa
     2821 gcgtcaacag ttgtacattc atcaacatca acatccaagc ccaagtcacg taatttgtct
     2881 gctacaatat ctgcaatttc ttcggtatta ccggtcatac tggcaaatac aatttttgct
     2941 aatgccatat cgtcctcctc aatttatctt tctccattat atcacatctt tttcatttta
     3001 aaaataaaaa ttcttgtgct acaatgaaat gagaaagaat tgaggttatt tatggagatt
     3061 tgccaacaaa ttttagaaaa aattaaagaa tacgacacca ttatcattca tcgtcatatg
     3121 aaaccagacc ctgatgcctt gggaagtcag gtgggattga aagccttgct agaacatcat
     3181 ttcccagaaa aaaccatcaa agccgtcggt tttgatgaac caactcttac ttggatggct
     3241 gagatggatc ttgttgaaga tagagcctac caaggcgcac ttgtcatcgt ctgtgataca
     3301 gctaatactg ctcgtatcga tgataagcgc tatagtcaag gtgattttct cattaagatt
     3361 gaccaccatc caaatgatga tgtatacggt gacctgtctt gggtcgatac tagttcaagt
     3421 agcgctagcg agatgattac cctatttgcc caaacaaccc aactagcctt ggcagatcgc
     3481 gatgctgagt tgctctttgc aggaattgtc ggtgatacag gtcgcttcct ctacccttct
     3541 accactgcac ggactcttcg cctggctgct tatttgagag aacataactt tgactttgcg
     3601 gctctcactc gcaaaatgga cactatgagc tacaaaattg ctaaactgca aggctacatc
     3661 tacgaccatc tggaagtgga tgaaaatggt gctgctcgcg ttatcctgag tcagaaaatc
     3721 ttgaaacaat acaatataac cgatgctgaa actgcggcca ttgtaggtgc acctggacgc
     3781 attgacagag tgagtctctg gggaattttt gtcgaacagg ctgatggcca ctaccgagtt
     3841 cgcttacgca gtaaagtcca tcctatcaat gaaattgcca aggagcatga tggtggaggc
     3901 caccctctag caagtggtgc taattcctat agcctagaag aaaacgaaat catctaccaa
     3961 aagttaaaaa acttgcttaa aaactgataa aatacttgcc aaacttttca gaatctgata
     4021 gactagtata gtaacaatct atggctcgca aagagaccat ggcagaaagg aaatattgca
     4081 aaatgaaaaa agatatccat ccagaatatc gcccagttgt cttcatggac acaactactg
     4141 gttaccaatt ccttagcggt tcaacaaaac gctctaacga aacagttgag ttcgaaggcg
     4201 aaacttaccc attgatccgt gtggaaattt catcagactc acacccattc tacactggac
     4261 gtcaaaagtt cactcaagca gatggacgcg tggatcgttt caacaaaaaa tacggtctca
     4321 aataatgata agagaacagt tttggctgtt cttttttgtt tcttgaaatc aactgctgtt
     4381 ttcatgttcc agactcatct gtaggttcga tttccatgct actaggcagg aaggaaatag
     4441 ctgtttcaac acgtccataa tgagctatac tattgtcacg aaccacactt tcattgatgg
     4501 tccaagtgga attcattttc ttaaaagctt ctcggacttt ttccaaatct ttggaggcaa
     4561 tggcctgctc taaggtttca aaacgaggac ttatactcat ctgctttcaa aaagcattct
     4621 agtccatctc cgattaccga tggactttat cacctccttc tccagtcctt gtatgacatc
     4681 ttgaagttga ttcatgacat cttccaaagt tcgaaaggct ttattcttaa atccacgttt
     4741 acgaatctct ttccacactt gttcaatggg ttcatctctg gtgtgtatgg aggaataaag
     4801 gtaaaatcaa tattagtcgg aatatttaag gtacttgatt tatgccatat agcattgtcc
     4861 ataacgagta aaaggataag cttgtgaaag ctcttctaaa aaggcgttca tccacactcc
     4921 tttttataaa cctgaaataa ggcatcaatt gtaacaaatt ctcctgcctc tgtagccttc
     4981 aaatgacggg caagaaaggc tttctcttcc tcaactgtca tatatgcatg gttacgacca
     5041 ccacgtgttt cttgaaggag agagtcgagt ccgaactcct catatttttt tacgtttcgc
     5101 caaatcgttg tttgattaca gtctaaaagc tctataatct ctttataaga tttgcccatc
     5161 agacgaaata tagtagattg aaactagaat agtacacctc tacttctaaa acattgttag
     5221 aaatcgattt gtcctgttct agtttcattt tactatagaa cgatttgaag gcgtttataa
     5281 tatttagctg tacgagagtc ttttaaaagt gttttgatgg tttggatttc ttctttagtt
     5341 gatttcatat tactattata taatgctttt tgattttagt ctggtataaa tattgctttc
     5401 ctccaaaatg gtcatagttt tactggcaaa tctaacatat cacggataaa ttaacaagtg
     5461 atttctgaat tgctaaacat tttcttttct tatagcatac tttaagattt tgtctttgag
     5521 aaagatattt ccaagaaaaa cgttcgtttt tttatctatt ttcaaaaaaa ccaaaaaact
     5581 gaattgaaag aatttttaga aaatttctgt tttttcttta cagtgaaaaa aaattctgct
     5641 ataatgtctt atgtaataaa atatgacaat aaaaggagaa cgatatgaca tctgctaaag
     5701 aatatatcca aagcgtgttt gaaactgtga aagctcgtaa cgggcacgag gctgaattcc
     5761 tccaagctgt tgaagaattt ttcaacactt tagaacctgt atttgaaaaa caccctgagt
     5821 atatcgaaga aaatatcttg gcacgtatta ctgagcctga gcgcgtggtt tctttccgtg
     5881 ttccttgggt tgaccgtgat ggaaaaattc aagtaaaccg tggttaccgt gttcaattca
     5941 actcagctgt tggaccatac aaaggtggac ttcgtttcca cccaactgta aaccaaggga
     6001 tcttgaaatt cctcggattt gaacaaatct ttaaaaatgt cttgactgga cttcctatcg
     6061 gtggaggtaa aggtggatca gacttcgatc ctaaaggtaa aacagatgct gaagtgatgc
     6121 gcttctgcca aagcttcatg actgaattgc aaaaacacat cggaccatca cttgacgtac
     6181 ctgctggtga tatcggtgtt ggtggacgtg aaattggtta cctttacggt caatacaaac
     6241 gtcttaacca atttgatgct ggtgtcttga ctggtaaacc tcttggattt ggtggtagct
     6301 tgattcgtcc agaagcaact ggttacggtt tggtttacta tactgaagaa atgctcaaag
     6361 ctaacggtaa cagctttgct ggtaagaaag tcgttatttc aggttctggt aacgttgctc
     6421 aatatgctct tcaaaaagca actgaactcg gtgcaactgt tatttctgtt tctgactcaa
     6481 atggttatgt catcgatgaa aatggtatcg acttcgatct tttggttgat gttaaagaaa
     6541 aacgtcgtgc tcgtttgact gagtatgcag ctgaaaaagc aactgcaacc taccacgaag
     6601 gtactgtatg gacttacgct ggaaactatg acattgctct tccatgtgcc actcaaaacg
     6661 aaatcaacgg tgaagcagct aaacgtttgg ttgctcaagg cgttatctgt gtatctgaag
     6721 gtgccaacat gccgagcgac cttgatgcca tcaaagttta caaagaaaat ggtatcttct
     6781 acggacctgc aaaagctgcc aacgctggtg gtgtagccgt ttcagctctt gaaatgagcc
     6841 aaaacagtct tcgcctctca tggactcgtg aagaagttga tggccgtctc aaagacatca
     6901 tgacaaacat cttcaacaca gctaaaacga cttcagaaac atacggtctt gataaagact
     6961 accttgcagg agctaacatt gctgcctttg aaaatgtagc aaatgccatg attgcacaag
     7021 gtattgttta agatttattt actcaatcct caatcactac gattggggat ttttagcttg
     7081 aattaaaaaa ttggaaaatc taattaaata aaatgaaatg aaataaaaac tgaacaaatt
     7141 gattgcggaa ttcaaaccaa tttctaacat atttctagaa attaatttga cttttctaat
     7201 cgatttgttc atatcttatt tcaatttact atacttactt gacc
//
LOCUS       DAVLHB010000070         7153 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLHB010000070 DAVLHB010000000
VERSION     DAVLHB010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.070"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(19..885)
                     /locus_tag="VXE36_001941"
     CDS             complement(19..885)
                     /locus_tag="VXE36_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0780177.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
     gene            complement(999..2822)
                     /locus_tag="VXE36_001942"
     CDS             complement(999..2822)
                     /locus_tag="VXE36_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV0780178.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            complement(2809..3174)
                     /locus_tag="VXE36_001943"
     CDS             complement(2809..3174)
                     /locus_tag="VXE36_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0780179.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            complement(3179..3535)
                     /locus_tag="VXE36_001944"
     CDS             complement(3179..3535)
                     /locus_tag="VXE36_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780180.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            complement(4367..5524)
                     /locus_tag="VXE36_001945"
     CDS             complement(4367..5524)
                     /locus_tag="VXE36_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780181.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LLGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNTTIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(5552..6313)
                     /locus_tag="VXE36_001946"
     CDS             complement(5552..6313)
                     /locus_tag="VXE36_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PezT"
                     /protein_id="HEV0780182.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(6313..6789)
                     /locus_tag="VXE36_001947"
     CDS             complement(6313..6789)
                     /locus_tag="VXE36_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0780183.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT         2119 a         1428 c         1029 g         2577 t
ORIGIN      
        1 actagaacac cgtattcctt attctgttat atctgcaaaa taatgttcga ctttcaaagc
       61 cattgacatg ttttcctcaa gtttgtagag aaaatgagca gtctcaaaat attcttttac
      121 tgaactttta gaagaaaaat tttcacttac acttcccatc aataaataca aatcagctaa
      181 tagataagtt gtcctgtact ccttacattg ctttatcgta gctgtgattt tcgtaatagc
      241 ttcttcaata tttttctgta accataggta tcgacaaacg ttataattga acttaattga
      301 tagttctaac tcttcaattg tgtttaaatt aagctgattc acttgatgct ctagcttgtc
      361 tctaatctca ttaaaacgtt ctaaatcttc aatatcataa taaaaattga atagagtgtt
      421 tgaaacttga aggtagttca aatcagatac atttaactga ggtagcatat tctctaatcg
      481 tgtaattgcc tcttctttct gtccataaaa ataaaaatct ataagagact ttatccattc
      541 catgtaaaat ttatctgcta gagataagcg atgggctttt acattttcca attcatatat
      601 atattttaaa gattcataat tacgatttgt gataaatgtc tgtgctaact tcttaaactc
      661 tgataactca ttgacttcct ctacaacctg ctcatcaaaa aagtagtcca tactaacttt
      721 taatttctta gcaagggcat gtaaaaaatc cgctccaggg gtgaactctc cactctctaa
      781 tcgactaatt tgcccctgtt tacagatacc ctcagctaat tctcgctgag acatttttaa
      841 ttcttttcgt ctatttttta atcttgttgc taatagtgta cccacgtttg catcttcctt
      901 ttctatttga tttcaatgtt aattgtaaca tgattaaatc taaatttcaa atatatttta
      961 caaaagatac acattgtata taattattgg ctagattcct atttttgaaa atctatccca
     1021 tctccttttg aaagtcctgt atttaagcga tttataaatt tatctagcct gactaccatc
     1081 ttttcatacc tgcccctttc caattccagt tgattcccca ggctcttcaa ttttttctca
     1141 acaatattag cactgatatt ctcagttata ttcagttttg aaagatttaa tttcatttct
     1201 tgcttacttt caactgaagc cagtagatat tctgctactt gattcaaggt tgacattcgt
     1261 tcttgcaact cattgattct caattcagac gctgctagtt catgcactaa ctcatcttta
     1321 atcgtgacat aagattgatt ttctacttcc agttcaatca aagcatccac ttccgcaatc
     1381 ttctctttaa tcatatcgac tgtcgctttt ctgcgtaatg gaatggtttg attttcatag
     1441 ctgaactgtc taattaaggt tcgacctttc atataacaat ttttctcggc agcgtctttg
     1501 tggtagacat agtaggagct ggtttccctg atgaaaacct tcaccttatc ctcttccata
     1561 tcaagctgca tgttcggcac aaagataagt ccctcctgac gaataccaaa cttgaccttg
     1621 acgtaaattc catcatccac tactttttca atttgattga gtgacaactc cacctcaaat
     1681 tcatgaacgg catctctgtt actcttgaac tcttgatagg actcccagaa cttctcatcg
     1741 cttggaagtt ctttttcttt ggataacttt tcttcttgat aaagttgaac gaaatcctca
     1801 gtttctggag cttgccaatc ttttctattt ttaaaataat cttggaaaaa ctctacatca
     1861 taaagatttt tctggtctag ctctgtctcc tttacctcca ctcctgcaaa ttgaaaagaa
     1921 acatgctttt gtttaggatt gatagttagt ccaaaaagtt ttgctttctg aagtaaatca
     1981 tccatattct caactttcag caataaaaat tccatgagac tttctatttc tcttttggca
     2041 aagtagttct taaaaaattc ttctgtgtaa ggctgcttgc gattgagttg cttgccacgc
     2101 accacctgtt tcatagttga gtccgtaata aaaaaggtgg catgcttgtg acggaaatcc
     2161 atctccacat gtagtagcgg agcattcttt ttgaaatcct caaagtccct agaatgttcc
     2221 atcaaaaaat agagtcgctg cttgagttca tacttgtgat tagtcttacg atagacttca
     2281 taccgctggt gagaatagcg gttctcaatg attttagcac ctgcgatttt agaaaaacgg
     2341 tcagaaatca tgcgaagatt tcgctccacc ttgtagtccc acttgagctt tttgtcagaa
     2401 ttgctatcta ctgaattgat aatgatgtga ttgtgcaggt ggtctttatc aacatgggtc
     2461 gcaacgataa aacgaaattt gccaccagtt aattccttca cagtctcata acctatccga
     2521 ttgatttgtt caggagtgag atgatcctct ggtgagaaag actgaatgat gtggtgagcg
     2581 tgtatttttc gttgattttc ttccatcctg tcgtggcgaa aatcgtaaag cgtatcgttg
     2641 ctgatgaaat tttcatgata catctgcacc atttcctcat agctaggaaa gtccagaaaa
     2701 ttcttcatgc catagtccga caccaaggca agattattgg ttttctcagg attgagaatg
     2761 tacttgataa gctttctgcg gtaactcttt ccgtgaatgg caaagtgttt agtgatgacc
     2821 atggaactcc tttagcttct gcgcttgcag attaaattcc ttatcaactt cttttatcaa
     2881 ttcaccaatt ccttttttca actcctgcaa ttcttcacca gaaattaact gagattgatt
     2941 aacacttcga gcaatctggt tgatattatt gccaatcctc tttaactcaa acactaaatc
     3001 ttggtaaccg tttgtgtcaa tcgtgataaa attcatacca ggatcgagta gagttcgtct
     3061 cgcatattca gaaaaggatt tacaaccact ttgatcgata tttatattta gttggttcaa
     3121 ctcactatca gacaaaaaca ctttcttgag attggttcgg taacgatgtt ccatgtgctt
     3181 acctcatgta cttctcacga aattctttac tgaggggtat ggtgtttgca acctcttgaa
     3241 tcaattcctg cacgcacgtt aagagaatag atacatgctc ttgggtgact tgacgttctg
     3301 actgtgccaa gattaaaact tcatgaacgt cacgactgat ttgttctagt ttttgggatt
     3361 gccagagggc aaaccatgtc tccatctgtt tttgtaaatc agaggaaagt aaacttttac
     3421 gaagaaaatc agagaaatta gtctctcccc gctctctcat caaagctaga atttgctttt
     3481 cttctgcttc tgttaaacga aattgtttcc gaatatcacg cacatctcgt ttcatactgc
     3541 tacttccttt ccaaaatact tgtactgaca atgtgagcta ccatacaatg tcagtacact
     3601 tttccaacaa ctgattttca ttcttgtaag gctttgcgag ctcagatatt gtgtccacaa
     3661 tatcccaaaa atcatatcgc cagcctatca aaacctacca gttttgacag ctaacgataa
     3721 gataacttag tggctccgcc cccaaacccc caggtaaaat tcttagttgg atttttaaaa
     3781 gttgagaaaa gtatagcaga agaaatttgg ggaagttatc acaaatcaag taaggactaa
     3841 tctctaacac cactgcatgt accgtcctat atttatgatc agctcccatc gtttacattt
     3901 tcaggtcact gtcttttcat accaggaatt agaattgaca aatttaatta gagaggtatt
     3961 catttaattg ttcacttctt cgctccattt ccattacaga aatttcttca atactatgtg
     4021 ttcagctgac tcccatgatt cgttgtacta cgtcctaaac gctcacggaa taagccgtac
     4081 atctttccta gtttactctc gtaatttacg tatataggtt acgacaccta tttggatttt
     4141 agagttcctc atccgctata tatggcttca agtcacgatt ctgtttgtag aaccttgatt
     4201 tcgctaattc cttcctatcc cccctacctc acgatattca ggcttaggag tcgctattgg
     4261 tttcatctgc agcaaatatc cacagaggac ttggacctca gatgtacact atgcctgtcg
     4321 gacaaagaaa aaagtaggct aaatttctaa cctacttttt ctgactctac tctgataaag
     4381 ccgtctcata tatagacatt ttatgcttga aggaatcttt tcctccctct aattgattga
     4441 tgatatgatt ttttatatat ttttcactaa catatccctg tgattcaatc catccgttaa
     4501 ctccatctga ctccataata acaacttgat ctgtcataga atttgttaca attgtagtat
     4561 tatgtgttgc taaaataatt tgacgttgag ctttcacatc tctaaactgc tgaactaaat
     4621 gcctgtaaat ataacgattg tctagattgt cttcaggctg atcaataatc aatggtctga
     4681 agtctttaga ataatcacta tatgctaata aaaaatcaag catggctaca actttttgtc
     4741 ccaaacttaa tacaccaact tctttataga gaatatcaag ttgttgcgaa gattctttcg
     4801 agttaatatt aaactccaaa aatcgtgtat tttctttaga aaaaattttt cgtttatatg
     4861 cacctaataa gtgagaacct tttttcaaaa tgtcataact attgaaatga gcaatatagt
     4921 taactatttt ttgattattg aaatccttca ttatagtcag tgaatgttga taacttccat
     4981 ctttctcact tataatattt tcacttaacc attgattaac ccatgattct tgttcataat
     5041 catatataca tacaatatgc aatttatctg ctgcactaat ttctactcca tgtaaaatat
     5101 gaggatgtat atcataaatc ggataatttt tcattatgat tgagactgcc atttgtaact
     5161 ttttaatacc tttggtagta ttatgatcag ttactacaac tatttctatt ccatttttta
     5221 tgattgcctc tgctaacata agaaaactaa tatattcttt tgaactagaa aaaacaacct
     5281 tatcaaaatt actaaaaaaa attgtcttat caacttttat tttcttattt tcaaaaaata
     5341 tatcatatag ttcatcttca gtaatttttc tatatttcgt tgcagtccaa ttagaaaata
     5401 gcttgtaatc ataagaaaca ggtgtatgca aatgaattaa agtcttgtga aagctaccga
     5461 atttctcttt ggaatttgtt agttcttgat aaacagactt tatcttgtta ttaaaccctc
     5521 tcatttctat tctcctaaaa atatcaattg tttatttttc aagtaattca ttaagtctct
     5581 tttcccccac ctgcaacatc tccttctcta cctgactcca ctccccaaag agtaactctt
     5641 gaagaacatc tgctgctgaa gttgtatttt cttttgaatc atatacacaa cttctatctc
     5701 gttggtaaat ttgaattctt tcaaagatag ctagttcttc caattttcgt gtgttatcaa
     5761 ctagatgatt tacaatgaaa tcatgatgtt cttttggagt tgcgcgtgct tgatttggat
     5821 tgataatgta cagttcttca taacggataa gagtacttag atacgacaat tcaggctttg
     5881 tcgcaattaa ggccaattgt acttcatatc ccttattttt caagagttgt gctgttttct
     5941 ttggaacatc aactgttcgt aaagttccct ctatcaaaag attgtatctc aaactactca
     6001 attttgttac taaagactct accatttttc ctgcaaaatc tttggtatat tctacactgt
     6061 ctttgccata ttcttgctgc agttctaaat agtgtggatg ctgagaacga aaactatcac
     6121 catctatgat aacaatattt ccttgaaatt ctttctgttt aatacgatga attgtagtct
     6181 taccggcacc actttgccct ccaagcaaaa tcgctatagg ttgcttactg gacttttttc
     6241 ctcttgtcag tgaacgaaga ttccttgcta aagcatgttt gaattcacta tcagtataat
     6301 cttggatttc cattaagcta ccatccgctt ttcagatatc tctaacatac gttcaattcc
     6361 atccaaatag ccactatatc tctctatttc atcaaaagtt tctactaaat agatattcgt
     6421 atgaatcaag tcagatagat catcactcat taaaatccaa ggattagatt catcatcaat
     6481 gctaattccc tgactatctt gataacgata gagtcgagat aatagattag cacctctttc
     6541 tttcacaatt tcaattttca aagtcaattc ataatcttca acaggattga gcattttatc
     6601 ttctcctaca atatcgacat aagatacatt aaacttctga caaatgatgt caattaattc
     6661 cgtagagact gaactagttc cattttcata acgactcaag ctatttcgag aaattcctat
     6721 aattcgtgca aattcgggtt gtgttaagtc atgtgtttta cgtaaggatt ttatgttctt
     6781 tccaatcata gcaaactcct ttatttttat aaatccatta tagcataaaa aagcataacg
     6841 caccaaaaat ggtgcgttat ttcttgtttt tctatcctaa actttacttc tataaaagtc
     6901 acctaaagag ctataaatat ttattcttgt attaattttt tcgatgcgca aacgatatct
     6961 acaaatacat ctataacgat tcacctttta ggatttttat tgtcaaaatt gcctttatct
     7021 acaaagacaa aatgcttata aaatagcttg aaatcaagga ttatcacctt tttcgttgta
     7081 gcaacactcc acatgtgatt attaggctat tagcaaagcg tatccaatac ctcaataaag
     7141 tgttgttttt act
//
LOCUS       DAVLHB010000071         6799 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLHB010000071 DAVLHB010000000
VERSION     DAVLHB010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6799
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.071"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            184..2341
                     /gene="blpA"
                     /locus_tag="VXE36_001948"
                     /pseudo
     CDS             184..2341
                     /gene="blpA"
                     /locus_tag="VXE36_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            2352..3713
                     /locus_tag="VXE36_001949"
                     /pseudo
     CDS             2352..3713
                     /locus_tag="VXE36_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            3770..3925
                     /gene="blpC"
                     /locus_tag="VXE36_001950"
     CDS             3770..3925
                     /gene="blpC"
                     /locus_tag="VXE36_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0780184.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(3970..5310)
                     /locus_tag="VXE36_001951"
     CDS             complement(3970..5310)
                     /locus_tag="VXE36_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0780185.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(5324..6061)
                     /locus_tag="VXE36_001952"
     CDS             complement(5324..6061)
                     /locus_tag="VXE36_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0780186.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6066..6404)
                     /locus_tag="VXE36_001953"
     CDS             complement(6066..6404)
                     /locus_tag="VXE36_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0780187.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
BASE COUNT         2224 a         1434 c         1103 g         2038 t
ORIGIN      
        1 attgtcatcg aaacgtcttg aattagcttt tttatttcaa gccacctcta aatgtttaaa
       61 aaaaataatt tctaatcact tttttaccat tcaggaagtt ttaatgacta ttcaagattt
      121 cataaaatat gaacttagtt ttatgacata atagacctat ccactatatg aaaagaattg
      181 ccaatgactt cttataaacg tacatttgtt cctcaaatag atgcgagaga ctgcggtgtt
      241 gctgccttag cctcgattgc taaattctat ggttcagatt tttctctagc tcacttgaga
      301 gaacttgcaa agaccaataa agaagggacg actgctcttg gcattgtaaa agccgctgat
      361 gaaatgggct ttgaaacaag acctgttcaa gcagataaaa cgctctttga catgagtgat
      421 gtcccttatc catttatcgt tcacgttaac aaagaaggaa aactccaaca ttactatgtt
      481 gtctatcaaa caaagaaaga ctatctgatt attggtgatc ctgacccttc tgtaaaaatc
      541 actaaaatgt caaaagaatg ctttttctct gaatggactg gagtagctat ttttctagct
      601 accaaaccca gctatcaacc ccataaagat aaaaagaatg gtctactaag caagcttcct
      661 tcctctgatt ttcaaacaaa aatctctcat tgcttacatt gttctctcaa gcttattggt
      721 cactattatc aatataggtg gttcttacta tctccaagga atcttggatg agtacattcc
      781 aaatcagatg aaatcaactt taggaatcat ctcagttggt ctggttatca cctatatcct
      841 ccaacaagtc atgagcttct ccagagatta tctcctaacc gttctgagcc agagattaag
      901 cattgatgtg attttatcct atattcgcca tatttttgaa cttcccatgt ctttctttgc
      961 gacacgtcgt acaggagaaa tcatttcacg gttcacagat gctaactcta ttatagatgc
     1021 cttggcttct accattcttt ctctttttct ggatgtttct attctgattc ttgtaggggg
     1081 agtcttgctg gcacaaaacc ctaatctctt cctcctttct cttctttcca ttcctatata
     1141 catgttcatc atcttttctt ttatgaaacc ttttgaaaaa atgaaccatg atgtcatgca
     1201 aagtaattct atggttagct ctgccattat cgaagatatc aacgggattg aaactataaa
     1261 gtcgctcacg agtgaagaaa atcgctatca aaatatagac agcgaatttg tagattattt
     1321 ggaaaaatcc tttaagctca gtaaatattc tattttacaa acgagtttaa agcagggaac
     1381 aaaattagtt ctgaatatcc ttatcctatg gtttggcgct caattagtca tgtcgagtaa
     1441 aatttctatc ggtcagctga ttacctttaa cacacttttt tcttacttta caactcctat
     1501 ggaaaatatt atcaacctcc aaaccaaact ccaatctgcg aaggtcgcta ataaccgttt
     1561 gaacgaagtc tatctagtcg aatctgaatt tcaagttcaa gaaaaccctg ttcattcaca
     1621 ttttttgatg ggcgatattg aatttgatga cctttcttat aagtatggtt ttggacgaga
     1681 taccttaaca gatattaatc tcacgattaa acaaggagat aaggttagcc tagttggagt
     1741 tagtggttct ggtaaaacaa ctttagccaa aatgattgtc aatttcttta aaccctacaa
     1801 agggcatatt tccatcaatc atcaggatat taaaaacatt gataaaaaag tcttgcgccg
     1861 tcatattaat tacctacccc aacaagccta tatctttaat ggctctattt tggaaaactt
     1921 aaccttgggc ggtaatcata tgattagcca agaagatatt ctaaaagctt atgaattagc
     1981 tgaaattcgt caagacattg aaagaatgcc tatgggctat caaactcagc tctctgatgg
     2041 agctggtcta tcaggaggac aaaagcaacg aatcgctctc gctcgtgctc ttttaactaa
     2101 atctcctgtt ttaatactag acgaagctac tagcggtctt gatgtcttga ctgagaaaaa
     2161 ggttatagat aatcttatat ccctaactga taaaaccatt ctctttgtag cccatcgtct
     2221 cagtatagcc gaacgaacta accgtgtcat tgttcttgac caggggaaaa tcattgaagt
     2281 tggtagtcac caagagttaa tgcaggcgca aggcttctac catcatctat tcaataaata
     2341 aggagaatgt catgaatcct aatcttttta gaagcgtcga gttttatcag agacgttacc
     2401 ataactatgc gacagtatta atcatacctc tgtcattact gtttactttc atcttgattt
     2461 tctcccttgt tgccacaaaa gaaattactg ttacttccca aggggaaatc gcccctacaa
     2521 gtgtcattgc atctattcag tcgaccagtg ataatcctat ccttgctaat catttagtgg
     2581 caaatcaagt agttgagaaa ggtgacttac tcatcaaata ctctgaaaca atggaagaga
     2641 gtcagaaaac tgccttagaa actcaattac aaagatttga gaagtaaaaa gaaggacttg
     2701 gaattttgaa acaaagctta gaaaaagcga ctgatctttt ttctggcgag gatgaatttg
     2761 gctaccataa tacctttatg aattttacta aacaatccca tgatattgaa ctgggtatca
     2821 caaagactaa cactgaggtt tcaaatcaag ctaatcttgc caatagcagt tcatcagcta
     2881 ttgaacaaga aattacaaaa gttcaacaac aaattggaga atatcaagag ctgagagatg
     2941 ctatcataaa taacagagca cgcttaccaa ctagcaatcc acaccagtca attttgaatc
     3001 gttatcttgt agcctcacaa ggacaaacac aaggaacggc agaggagcca tttttatctc
     3061 aaattaatca aagtattgca ggtcttgaat catctatcgc aagcctcaaa attcagcaag
     3121 ctggtatcgg aagtgtagca acttatgata atagtttagc agccaaaatt gaagtactcc
     3181 gcactcaatt tttacaaaca gcttctcagc aacaactaac cgtggagaac caattaacag
     3241 aattaaaagt acaactagat caagcgacac agcgcttaga aaacaatacc ttaaccgctc
     3301 caagtaaagg tatcgttcat ctgaacagcg aatttgaagg taaaaataga attccaactg
     3361 gtacagaaat tgctcaaata ttccctatca tcacagatac aagagaagta ctaatcactt
     3421 actacgtagc ttctgactat ctacctctac tagataaagg acaaactgta agattaaaac
     3481 tggagaagat tggaaatcac ggcattacca tcatcggcca acttcagaca attgatcaaa
     3541 ctcctaccag aacagagcaa ggcaatctct ttaaattaac cgctcttgca aaactatcta
     3601 atgaggatag taaactcatc caatatggct tacaaggtcg cgtcactagt gtaactgcaa
     3661 agaaaacata ttttgattat ttcaaagata aaattttaac ccattctgat taattttcag
     3721 ataacaccct ataactattt attatcttat caaaaaggag aatcataaca tggataagaa
     3781 acaaaaccta acttcatttc aagaactaac aactaccgaa ctcaaccaaa ttacaggtgg
     3841 aggactgtgg gaagatatct tatacagcct taatataatt aagcataaca atacgaaagg
     3901 acttcatcat ccaatacaac tataaaaaat aagaccgagt aacaagaact ctcggtctta
     3961 tttttttcat cattctgtag gtatcatagt aagcacctga cgaaagactt gatcttgaca
     4021 ggtagtattt aaactggcat tgggataact ttccacaatc ttcataacgg tatagagacc
     4081 gacacctctc tcctcccctt tagaactaac tccaaaggag aagatttcag aaatatctat
     4141 gccctcttct ttgatggaat tttcgatgat gaaggtctcc tgtgctccac tttttaaaaa
     4201 ggcaattgaa acatgaggtt gaccggcctc tgcactcgct tcaatagcat tatcacaaag
     4261 gatagacaca atggttagaa aatcaagcag tctcatcccc tcaacctgaa tctcttcagg
     4321 aacttcgaca ttaaagacaa tgtccttttc tctagctttt ataaattttc cagctaggag
     4381 acttttgagg gcacgatccc gaacattcac caatcggcca aggtcatatt tattgtcctg
     4441 caatttttta ctagaatcct ttaagaccaa gtcatagacc tcttttatct gctccatatc
     4501 ctcctcttca atacccagac gtaaacttgt caagaggttg gtgtagtcat ggcgaaaact
     4561 ccttacttcc ttgtaaagtt cctctatatg ccgactatag cgttccatat ctctatagcg
     4621 caagacctgc tcttggtcca gtctatcatg gagtttgtcc ttcaaatagg tatccaattt
     4681 cttgataacc cccataaaaa agagcaggta aaacactagg atgagatggc gaacagtcgt
     4741 tgattgaata ccttgctcat attcaaagta agacagactt tgtatcacca aatagtaagc
     4801 ccccattatc cagttaatct tagtcaggga cttttgaaaa cctgtatcta gaatctccct
     4861 tctcaagcta gtaaaatcgt agtccaacca tttcaaaaaa gctagagaaa tgaagaaatt
     4921 gaaaattatt atacataacc cagtaaatga gtagccatca tatacttgcc cttgtcccaa
     4981 aaatggaagc acaaaatagg agactcctct ataaaagaga ttcaccaata tcattggaaa
     5041 gagaccataa aagaaaagga gttttttagg aagccctctc aataataaga aagataagcc
     5101 tatgccgtac aagggttcca taaaataaga taggtaaaca tttcctacta tatagctaat
     5161 catcacaaaa acaaaggcca acagtatctt caaaagaaag gccttaaaaa tcctctcgaa
     5221 agtaagatca attccatcca ccttaaagaa gatgacaatt tctagtccat tagtaacaag
     5281 tgtatacaac aatatccaag caatgttcat aaattctcct agctcagtgt aatttattga
     5341 tggcctcaga cacttccctg accttataac gggcgattag acaacttcca ccattgggaa
     5401 agaaaagcag tttttctttc ttatccaaat gcaccacatt tgcaggattg atgagaaaag
     5461 agcggtggca ctgcaagaga cggggctcct gcttgaaaac ctcctctaaa ctcgctgtaa
     5521 attccagcct gtctgtcttg gtatagagaa taacacgatg ggctctgggc gacgtttcga
     5581 gatagtaaac ctctttaaaa ggatactgaa attgggcaaa ttttgattta aagtaaaagc
     5641 aatcttccgc cagactttta ctatcttgac tattggcata gaggagggct gtctcgatcc
     5701 gagattcaaa ctcctctgct gacaaggcct tatcaatgta gtccaaagca gacacttggt
     5761 agcgaaaaga caggggcata aactccgagt gagtcgtcac aaagacaatc agggcataag
     5821 gatcccgatc ccgaatcttt ctagccactt ccagtccctt catctcttca tttcgaatct
     5881 caatatccaa aaagaatagc tgatgggccc ccttctcatg cacttcagcc agcagttggt
     5941 ccggcttgcc aaatacctca aaagagctag gaatgatatg atgtgctttc aaaagtttct
     6001 caatcgtcgt ttcaattcta gtctgttggg aaaaatcatc ctctaaaaca aatattctca
     6061 tcttcttact ctccctcttt caaccatttt tgacgaattt ctctatagcg acgtctggca
     6121 tacttgacag cgtattgacc ttcttctccg agaaaaagga ttctttcttg aaaatcaatc
     6181 gattttaatt tatcaagatt aaccaaacaa tttcgatgac atctcatcaa ggtttcccca
     6241 cattggttct caagattact taaattttga agcatattaa aactagcttc ttctgtaaca
     6301 atctgtacgg tatgggcttt agttggatgt gtttggatat agtagatatc gtcgatgttt
     6361 actttataga ctgttttctg cgtctgaata atcatatatt tcattggatt ctcctcctaa
     6421 gaaaagaata acagaaaagg tctagcccaa gcacacccaa tcctaaacag tctttgaaaa
     6481 ctcctaaaag gattattttc tacaacatca tgatgagctt acaactattt tatcataaaa
     6541 ttcactcagc gcaattcaag acatttcaat gacaattaac ccaaatcatt catacctctc
     6601 tcaactagat gtaacttaca aaacccctga cctcatgagc cactttcttc ctcctcatga
     6661 ggtcagtttt actttctgct gttccagtat cgtttttcct cgctagattt cctcaaaagg
     6721 gcagactcct cccttggtgc gtcacacgat tttttcatct cgactgttct ttaatgcatc
     6781 attaacgacg cttttcttc
//
LOCUS       DAVLHB010000072         6668 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLHB010000072 DAVLHB010000000
VERSION     DAVLHB010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6668
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.072"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            1..431
                     /locus_tag="VXE36_001954"
                     /pseudo
     CDS             1..431
                     /locus_tag="VXE36_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            586..786
                     /locus_tag="VXE36_001955"
     CDS             586..786
                     /locus_tag="VXE36_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780188.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            811..1227
                     /locus_tag="VXE36_001956"
     CDS             811..1227
                     /locus_tag="VXE36_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780189.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1458..2165
                     /gene="ccdA2"
                     /locus_tag="VXE36_001957"
     CDS             1458..2165
                     /gene="ccdA2"
                     /locus_tag="VXE36_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0780190.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2176..2733
                     /gene="sdbB"
                     /locus_tag="VXE36_001958"
     CDS             2176..2733
                     /gene="sdbB"
                     /locus_tag="VXE36_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0780191.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3107..4498
                     /locus_tag="VXE36_001959"
     CDS             3107..4498
                     /locus_tag="VXE36_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0780192.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4641..5558
                     /gene="adcAII"
                     /locus_tag="VXE36_001960"
     CDS             4641..5558
                     /gene="adcAII"
                     /locus_tag="VXE36_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0780193.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSILAEELK"
     gene            5566..>6668
                     /locus_tag="VXE36_001961"
     CDS             5566..>6668
                     /locus_tag="VXE36_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0780194.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEERI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSP"
BASE COUNT         2049 a         1235 c         1393 g         1991 t
ORIGIN      
        1 ttgactgaaa tagcttctga atttggctgt catccaacta ccatccacta tgcgctcaaa
       61 gctatggact acactcgaaa aaaagaacca cacctactat gaacaagacc cagaaaaagt
      121 agccttattt cttaagaatt ttaatagatt aaagcaccta gcacctgttt agattgacga
      181 aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag gtcagttaat
      241 aagaggcaaa gtatctggaa gaagatatca gagaatttct ttggttgcag gtctaacaaa
      301 tgaatggtga gttaatcgct ccaatgactt acgaagagac gatgacgagc gacttttttg
      361 aagcttggtt tcagaagttt ctcttaccaa cattaaccac accatcggtt attatattaa
      421 aacgaaataa gaataggaca aatcgatcag gacagtaaaa tcgaattcta acaatgtttt
      481 agaagtccat atgtactatt ctagtttcaa tataccataa ctgctcctag tcaacctgca
      541 agtcctgtcc cagctccaag ctcagctccg actcaagatc ctagagtggt agtaagcgct
      601 tcggctagct caacgagccc acaagctcaa gagcaagttg acaagtctga acttcgtgcc
      661 ttgagtcaag agttagacca acacttgaaa gctttggcaa cagtatctga tccgaaaatc
      721 gatgcaacca aggctgtcct cctagatgct caaaaagctc cggaagatag tgccttgaca
      781 gagtaaggtc tgcatactgc agtagagtct gtgaaggctg ccttggactc tctcaaagat
      841 gtgaaagcaa atgctagcga cagcaagcct gcacaggaca agaaggatgc aaaacaagga
      901 acggaagata gtaaggattc agataagatg actgaaacaa actcagttcc ggcaggagtg
      961 attgtggtca gtctacttgc cctcctaggc gtgattgcct tctggctgat tcgccgtaag
     1021 aaagagtcag aaatccagca attaagcacg gaattaatca aggttctagg acagctagat
     1081 gcagaaaaag cggataaaaa agtccttgcc aaagcccaaa accttctcca agaaaccctt
     1141 gatttcgtga aagaagaaaa tggctcagca gagacagaaa ctaaactagt agaggagctt
     1201 aaagcaatcc ttgacaaact caagtaaaac atgatttatg aaatgtcaga cttaaaagac
     1261 attttcgttc acaaaagcag cgacgagtaa tccttgtcgt tgctttttgg ctattttggg
     1321 ggataagatc cgccttgact agcaaaagaa aagattggtc caatagtgcc cgatacgatt
     1381 ttgcgtagca gaaagcttac aaataaaatt gaatatagta aaataggatt agaattatta
     1441 agaaagttgg ttctttattg gaaacgatag tatttttaat ctctgttttt ctagcaggtg
     1501 ttttatcctt tttttctcct tgtatttttc ctcttctgcc agtctatgct gggattttat
     1561 tggatgatca agaaagtgca aaaagctttt ctttgtttgg gagaaaggtt ctctggtcag
     1621 gcttgattcg aacactttgc tttatcgctg gtatctctct cattttcttt attctaggct
     1681 ttggtgctgg ttactttggt catattctct atgcaaattg gtttcgatat ggcatgggag
     1741 ctattattat cattttgggt cttcaccaga tggaaatttt tcatttgaag aaattagaag
     1801 ttcaaaaaag ttttaccttt aaaaaatcag attctaatcg ttattggtca gcttttttac
     1861 ttggtattac ctttagcttt ggttggacac cttgtattgg tccagtttta agttctgttt
     1921 tagcacttgc ggcttctgga ggcaatggcg cttggcaagg agcgatttat actctcattt
     1981 acactctggg catggccctt cctttcttgg tattggcact agcttcaggt ctagtcatgc
     2041 catattttag taaaatcaag cgtcatatga tgctactaaa gaaaattggt ggtttcctca
     2101 ttgttttaat gggaattttg ttactattag gacaagtaaa tgttctagct ggaatttttg
     2161 aataaaggag gacaaatgaa aaaagtaatg tttgctggct taagtctctt gtcattagtt
     2221 gtattgatgg cctgtggtga ggaagaaact aaaaagactc aagcagcaca acagccaaaa
     2281 caacaaacga ctgtacaaca aattgctgtt ggaaaagatg ctccagactt tacattgcaa
     2341 tccatggatg gcaaagaagt taagttatct gattttaagg gtaaaaaggt ttacttgaag
     2401 ttttgggctt catggtgtgg tccatgcaag aaaagtatgc cagagttgat ggaactagcg
     2461 gcgaaaccag atcgtgattt cgaaattctt actgtcattg caccaggaat tcaaggtgaa
     2521 aaaactgttg agcaattccc acaatggttc caagaacaag gatataagga tatcccagtt
     2581 ctttatgata ccaaagcaac caccttccaa gcttatcaaa ttcgaagcat tcctacagaa
     2641 tatttaattg atagccaagg aaagattgga aagattcaat ttggtgctat cagtaatgcg
     2701 gatgcagaag cagcatttaa agaaatgaac tagaatcgat aaaatctgat tacaagatgt
     2761 agtcagattt tggtaacttc taaaactaac ttccagtttc ccacaaccta gcttttagta
     2821 tgagaaaaac gcgtgacatc agtggaaatc cgtcttagac taacttccac tggttttctt
     2881 tttcttgata tataagggtt caaaagcgaa aagactcaga aaaagtgcac gacaaatagc
     2941 cctaaaacag agtcgtctta gagtaacttc cagttttggg agagagatgg aagttacttt
     3001 gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc acatatctcc
     3061 tatatttatg gtaaaataga attatcagtt tattttggag tcaaagatga atatatttag
     3121 aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt tatgggattt
     3181 gattttgctg ggtatcggag ccatggtagg gacaggcgtc tttacaatca caggtactgc
     3241 agctgcaaca cttgctggcc cagccctagt gatttcaatc gttatttctg ccttgtgtgt
     3301 gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta caggaggtgc
     3361 ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg gttggttaac
     3421 catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag cttattttaa
     3481 aggcttgctc tctcaatacg ggatagcctt tcctcaggct ttaaatggta cctttaatcc
     3541 tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg tgacttcgct
     3601 tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta ttttgaaatt
     3661 ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg ataattggag
     3721 caattttgct ccttacggtt ttggacaaat ctatggagct agcactggta ttatggctgg
     3781 tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg ctgtagatga
     3841 agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt ctatcgtaac
     3901 cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata gtcatttaaa
     3961 tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg cagccaacta
     4021 tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga cctatgccct
     4081 atcgcgtatg atttacagtt tagcacgtga cggcttagtg cctgctgcct ttaaggaact
     4141 gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag cttcagcagt
     4201 agcagcagga atgttcccac tagccagtat tgcagccttt ttaaatattt gtaccttagc
     4261 ctacttaatc atgttggctt atggtctgat tcgcttacgg aaagaaaaag gaatgcccaa
     4321 agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga tcatcatttg
     4381 tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag ttgcgttgtt
     4441 agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag aagaataaag
     4501 tgaaagtcta ttgagttgtt gacactcagc agatttttat atgtgaaaga aatttcaaat
     4561 tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta ctagttaatt
     4621 aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg ttaagtgtct
     4681 ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag gggatgaaaa
     4741 ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt gacttgaatg
     4801 atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg gcaaatgata
     4861 tcgcagccat ctatgatgca gatgtctttg tttaccattc tcatacactc gaatcttggg
     4921 caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag gcttctgagg
     4981 gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat ggagttgatg
     5041 aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga gaagaagccc
     5101 aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact tatcaaaaaa
     5161 atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa ccaaaatttg
     5221 aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat ctagcgaaga
     5281 gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa ccaagtccac
     5341 gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg atttttacag
     5401 aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt gtgggtctta
     5461 aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta gaaaatctgg
     5521 aagaaaatat gagtattcta gcagaagaat taaagtgagg aaagaatgaa aatcaataaa
     5581 aaatatctag caggttcagt ggcagtcctt gccctaagtg tttgttccta tgaacttggt
     5641 cgtcaccaag ctggtcaggt taagaaagag tctaatcgag tttcttatat agatggtgat
     5701 caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag agaggggatc
     5761 aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc tcatggagac
     5821 cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga agagctcctc
     5881 atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat caagggtggt
     5941 tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc tcatgcggat
     6001 aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca taatcacggg
     6061 ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta tacaacggat
     6121 gatggttata tcttcaatgc atctgatatc atcgaagata cgggcgatgc ctatatcgtt
     6181 cctcatggca atcacttcca ctatattcct aagagtgatt tatctgccag tgaattagct
     6241 gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag ttctagtcat
     6301 aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt cactccaact
     6361 tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta tgctaaaccc
     6421 ttatcagaac gccatgtgga atcggatggc cttattttcg acccagcgca aatcacaagt
     6481 cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat cccttatgaa
     6541 caaatgtctg aattggaaga acgaattgct cgtattattc cccttcgtta tcgttcaaac
     6601 cattgggtac cagattcaag accagaacaa cccagtccac aaccgactcc ggaacctagt
     6661 ccaagtcc
//
LOCUS       DAVLHB010000073         6531 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLHB010000073 DAVLHB010000000
VERSION     DAVLHB010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6531
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.073"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            173..1456
                     /locus_tag="VXE36_001962"
     CDS             173..1456
                     /locus_tag="VXE36_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0780195.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(1651..3222)
                     /gene="ffh"
                     /locus_tag="VXE36_001963"
     CDS             complement(1651..3222)
                     /gene="ffh"
                     /locus_tag="VXE36_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0780196.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(3234..3566)
                     /locus_tag="VXE36_001964"
     CDS             complement(3234..3566)
                     /locus_tag="VXE36_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0780197.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(3656..4033)
                     /locus_tag="VXE36_001965"
     CDS             complement(3656..4033)
                     /locus_tag="VXE36_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0780198.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDRQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            4105..5409
                     /locus_tag="VXE36_001966"
     CDS             4105..5409
                     /locus_tag="VXE36_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0780199.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            5422..6228
                     /gene="yidA"
                     /locus_tag="VXE36_001967"
     CDS             5422..6228
                     /gene="yidA"
                     /locus_tag="VXE36_001967"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0780200.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
BASE COUNT         1858 a         1515 c         1205 g         1953 t
ORIGIN      
        1 ttttttctgc tatactatcc taagcaaagg tttttaatgt catcccgtga ggtgacgaag
       61 acgcagaaat atttgaaact ctttaaagtc tagattttag agaagtctta ctctgagggc
      121 ctattgctgt aaaataatgg gctcttttct gatgcccaaa agtgaggttt atatgaaaca
      181 agaatcaact gttgatttgt tactagacgt tgaccaacgt ccttcggatg gaaaaggaat
      241 tctccttagt ttccaacacg ttttcgccat gtttggtgcg accatcttgg taccattgat
      301 tttgggaatg cctgtatctg ttgccctttt tgcttcaggt gttggaacac tcatctacat
      361 gattgctact ggttttaaag ttccagttta tctaggttct tcatttgcct ttatcacagc
      421 tatgtcactg gctatgaaag aaatgggggg ggatgtatct gctgcccaaa caggggttat
      481 cttgactggt ttggtctatg tccttgttgc taccagcatc cgatttgtag gaacaaaatg
      541 gattgataaa ctcttgccac caatcattat cggtcctatg atcatcgtta tcggtcttgg
      601 acttgcaggt tcagctgtta ccaatgcagg tcttgtagca gacggaaatt ggaaaaatgc
      661 tctggtagcc gttgttactt tcctaattgc tgcctttatc aatacaaaag gaaaaggctt
      721 cctacgaatc attccattcc tctttgccat tatcggtggt taccttttcg cactaactct
      781 tggcttggtt gactttacac cagttcttaa agccaactgg ttcgaaattc ctggtttcta
      841 cttgccattt agcacaggtg gtgcctttaa agagtacaat ctttactttg gtccagaagc
      901 catcgctatc ttgccaatcg ctatcgtaac aatttctgaa catatcggag accatactgt
      961 tttgggtcaa atctgtggtc gtcaattctt aaaagaacca ggtcttcacc gtactcttct
     1021 tggtgacggt atcgcaactt ctgtttctgc cttccttggt ggaccagcca atacaactta
     1081 cggagaaaat acaggggtta tcggtatgac tcgtatcgct tctgtctcag ttatccgtaa
     1141 cgctgccttc atcgcgattg ccctcagctt ccttggtaaa ttcactgcct tgatttcaac
     1201 tattccaaac gctgtacttg gtggtatgtc aatccttctc tatggggtta tcgccagcaa
     1261 tggtttgaaa gtcttgatta aagaacgtgt tgatttcgct caaatgcgaa acctcatcat
     1321 cgcaagtgct atgttggttc ttggacttgg aggagctatc cttaaacttg gtccagttac
     1381 actttcaggt actgcccttt cagccatgac aggaatcatc ttgaacttga tcttgccata
     1441 cgaaaataaa gactaagagt ctaaatacac ctaatccact cagacagctg agtggatttt
     1501 tcgcatacca taataaaagt gtcttaacaa aattattaaa atcaaaaaac gtataatatc
     1561 agatattcta aaaccttgat actgtacgtt ttatcataga aatttttact ttattttctc
     1621 atcaaatgag atttgcatca atctcttgtc ttacttgcgt ttcttcttcg ctttcttcat
     1681 tttgttagcc atacgtttca tggactgttt catggcaaat tcaccaattt tacctttcaa
     1741 accgccacca aacatctggc tcatatctgg cattcctgct cctccgagag ctgataagtc
     1801 aggcataccg ccttgtccca tcattccttc aagggcagac atatccattc ctcccatatt
     1861 tggcatattt ttaggaaggt tatttggatt aatccccatt tgcttcatca ttttattcat
     1921 atccccagac ataacaccct gcatgagctg tttagcctgg ttaaagtcct tgatgaattt
     1981 attgacttcg acgaatgtat ttccagaacc agcagcaata cgacggcgac ggcttggatt
     2041 taacaaatct gggttttcac gctcttcagg tgtcatcgaa gacacaatgg cacgtttacg
     2101 agcaatctgg cgttcatcca ccttcatgtt ttgaagggct ggattgttgg ccatacctgg
     2161 aatcatcttg agcaagtctt ccatcggccc catattttgc acctgatcta attgatcgat
     2221 gaaatcatta aaatcaaagg tgttttcgcg catcttctca gccatttcaa gggctttttg
     2281 ttcatcgtat tcctgagaag ctttctcaat caaagtgagc atatccccca taccaaggat
     2341 acggctagac atgcggtctg ggtggaaggt ttcaatgtcc gtaatctttt cacctgtacc
     2401 agtgaacttg attggttttc cagtaatgtg acgaacagac agagcagcac caccacgagt
     2461 atcgccatca atcttggtaa ggatgacccc agtcacttcc aactgagcat taaactcacg
     2521 cgcaacattg gctgcttcct gaccaatcat agcatcaacg acaagcaaga tttcatttgg
     2581 ttgagccaat gctttcacat cacgaagctc attcatgagg agctcatcaa tctgcaaacg
     2641 acccgcagta tcaatcaaga catagtcgtt atgattagtt tgggcttgct ccaaaccttg
     2701 acgtacaatc tcaacagctg gtacttctgt tccaagtgca aagacaggca catcaatctg
     2761 ttgtcccaag gtcttaagct ggtcaatggc agctggacga taaatatccg ccgcaatcat
     2821 caaaggacga gcattttctt ctttcttgag tttgttggcc aatttaccag caaaggttgt
     2881 tttaccagcc ccttgtaaac caaccatcat gatgatggtt ggaatcttag gtgacttgat
     2941 aatttctgcc gtatcagaac ctaaaacggc tgtcagttcc tcatcaacga ttttaataat
     3001 ctgttgcgca ggattaagtg tatcaatgac ctcatgcccg actgcacgct cacgaacttt
     3061 cttgataaag tcctttacaa caggcaaggc aacgtcggcc tcgagcaagg ccaagcgaat
     3121 ttctttggtt gcctcttgga catcagattc agagattttt ccttttttac gtagattttt
     3181 aaagacgttc tgcaaacgtt ctgttaaact ttcaaatgcc atttttcttc ctcttattct
     3241 ctattatcaa tgcttgttaa aatttctatc tgctcctgca gaaagttatc cttgggatag
     3301 cgctccaaaa tctgatcaaa aatctgactg cggacaatat agtccgagta catgtgcaat
     3361 ttcatctcat aatcttccag aatcttttct gttcgcttga tattgtcata gacagcctga
     3421 cgactgacac cgaactcctc ggcaatttca gcaaggctgt aatcatcagc gtagtagagc
     3481 tcgatataat tcatttgctt atctgtcaaa agcgccgcat aaaattcaaa gagcgcattc
     3541 atacgattgg ttttttcgat ttccataact tttattatac caaaaaatag cctaatctac
     3601 cacactaggg agccaatcct tgaagataga aagtagattt gagaaaaacg agatcctagc
     3661 cccaagtaat ttccaattga tagctggcaa agggatgccc ctcttgattt tgtagttgat
     3721 aagctagctc aatcttttgc ctatcaactt gataacggct cgtttgaatg ataaattcct
     3781 gcatgcccat aggggtagga atataggcca aactatcact atcctttaaa aagcgcataa
     3841 tggtcttggg attagaaaat cggctcatca ccagttcttg accatgaaat ttaataacta
     3901 ctttttcctt ttcctcatta taaaagagta aatagctata atctcccttt tcatgcactt
     3961 ccacatcata aagctggtca atcacttcca actgctcatc aaactgaatc gtatttcgca
     4021 tccgaatctt cacatcaggt cctctttctt gtctcttgtc ctactatttt accaaaaaga
     4081 gcaggatttt gctataatgg tcatatgaac gaaaaagtat tccgtgaccc tgttcacaac
     4141 tacatccatg tcaataatca aatcatctat gacttgatta atacaaaaga atttcaacgt
     4201 ttgcgccgga tcaagcaact agggacttcc agttatacct tccacggtgg agagcatagt
     4261 cgcttctctc actgtctggg agtctatgag attgcacgac gtatcacaga aatttttgaa
     4321 gaaaaatatc ctgaggaatg gaatcctgcc gagtctctct tgaccatgac cgctgctctc
     4381 ctacacgacc ttgggcatgg tgcctactcc catacttttg aaaatctctt tgatacagac
     4441 catgaagcca ttactcagga gattattcaa aatcctgaga cagagattca ccaagtcctg
     4501 ctacaagtgg cacctgattt cccagaaaag gtggccagtg tcattgacca tacctatcct
     4561 aataagcagg tcgtgcagct catttctagt cagattgacg cagatcgcat ggactatctc
     4621 ttgcgcgact cctattttac aggagcatcc tatggggaat ttgacctgac tcgaatcctc
     4681 cgagtcattc gtcctatcga aaatggtatc gcctttcagc gcaatggcat gcacgccatc
     4741 gaagactacg tcctcagtcg ctaccagatg tacatgcagg tttatttcca ccccgcaaca
     4801 cgcgccatgg aagttctcct acagaatctt ctcaaacgcg ccaaggaact ctatcctgag
     4861 gacaaggatt tctttgcccg aacttctcca cacctcctgc ctttcttcga aaaaaatgtg
     4921 accttgactg actatctggc tctggatgat ggcgtgatga atacctactt ccagctttgg
     4981 atgaccagtc ctgacaagat tcttgcagat ttatcgcatc gctttgtcaa ccgcaaggtc
     5041 tttaaatcca ttaccttttc acaagaagac caagaccaac tcgctagcat gagaaaattg
     5101 gttgaggaca tcggctttga tcccgactac tatactgcca ttcataagaa ctttgacctc
     5161 ccttatgata tttaccgtcc cgaatctgaa aatccaagga cacagattga gattttacaa
     5221 aaaaatggag aactggcaga actctctagc ctgtccccta tcgtccaatc ccttgctgga
     5281 agtcgccacg gagataatcg cttttatttc ccgaaagaaa tgttagacca aaacagcatc
     5341 ttcgcaagca tcacccagca atttttacac ttgattgaga acgatcattt taccccaaat
     5401 aaaaactaaa agaggaaatt tatgagtatt aaactaatcg ccgtcgatat tgacggaacc
     5461 ctagtcaaca gccaaaagga aatcactcct gaagtctttt ctgccatcca agatgccaaa
     5521 gaagctggtg tcaaagtcgt gattgcaact ggccgcccca tcgcaggtgt tgccaaactt
     5581 ctggacgact tgcagttgag agaccaaggt gactatgtgg tgaccttcaa tggtgccctt
     5641 gtccaagaaa ctgctactgg ccatgagatt atcagcgaat ccttgaccta tgaggattat
     5701 ctggatatgg aattcctcag tcgcaagctc ggtgtccaca tgcatgccat taccaaggac
     5761 ggtatctata ctgcaaatcg caatatcgga aaatacactg tacacgaatc aaccctcgtc
     5821 agcatgccta tcttctaccg tacccctgaa gaaatggctg gcaaggaaat tgtcaagtgt
     5881 atgttcatcg atgaaccaga aattctcgat gctgcgattg aaaaaatacc agccgaattt
     5941 tacgagcact actctatcaa caaatctgct cctttctacc tcgaactcct taaaaagaat
     6001 gtagacaagg gttcagctat tactcacttg gctgaaaaac tcggattgac caaagatgaa
     6061 accatggcaa tcggtgacga agaaaatgac cgtgccatgc tggaagtcgt tggaaacccc
     6121 gttgtcatgg aaaatggaaa tccagaaatc aaaaaaatcg ccaaatacat cactaaaaca
     6181 aatgacgaat ccggcgttgc ccacgccatc cgaacatggg tactgtaaaa gtatcatttt
     6241 tcaataagaa ttgattagca ataaaatcca atgaattttt ttagcaaact atttaattta
     6301 aaacaaaata atcataatag agacacaaat tctgattgta acaattttta cctaaacgat
     6361 ttagaatgtg gccttactcc tgggcaactc atactcatag attggactca aaaaacaggg
     6421 agaaattata atttcccaag atattttaaa tactctcttc aaattgaccc tgaatctaca
     6481 cacaatcaat tatacaaatt aggatacttc actaaaaata agactttatc a
//
LOCUS       DAVLHB010000074         5912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLHB010000074 DAVLHB010000000
VERSION     DAVLHB010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.074"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..1187
                     /locus_tag="VXE36_001968"
     CDS             <1..1187
                     /locus_tag="VXE36_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEV0780201.1"
                     /translation="PAFIQILCIVFGVLAIYKINNKLKDFRYELDFDLIIRESLLFGL
                     YTNHLYTSEKDNSGYEEIIRSAILKYELDNQNGRIIIKALIRGDEFSKKVQTLDDVLA
                     GVLELELEEKITHPNIVEYHFYYKKPDRLILSPHDHKKEIDSLDIDLGYDITYNPIKC
                     PHILVSGGTGSGKSIFISFLIIELLKRNSTLYIADPKNSDLGSLSHYLSDKYVATTPN
                     SIARIVRLVVEQMQARYQTMRDNFHYGSNFADHGFKPVWLIFDEMGAFQASATDKKSK
                     EVITEVMDGIKQIILLGRQAGVFILISAQQMRAETLNTDLRDNLGLRIALGANSIEGY
                     RMVFGTATPDKFKSIEEKGAGYLYMQGSGKEKAQYWESPYLDTTQFDFIKELQLYVTK
                     SK"
     gene            1284..1598
                     /locus_tag="VXE36_001969"
     CDS             1284..1598
                     /locus_tag="VXE36_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780202.1"
                     /translation="MKINDFLKPELLGNKFVAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQIKVNTLSPTATPQLLSDKKTCPIKLSNLTVGQFNGNLWFSCNDVVPI
                     SK"
     gene            1615..2343
                     /locus_tag="VXE36_001970"
     CDS             1615..2343
                     /locus_tag="VXE36_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0780203.1"
                     /translation="MAKLFAISDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDNGH
                     QSFQVISKIIELEELHPNQIITLLGNHEEWFYDWLILENPTSSSFSETIKSFFSPEEL
                     TYILKSNVNNFEAGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GKLWKDLTSSEMFTNKFPLTTGEFFKDIVSGHVASWEVAKDKAYQGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVTKSYQY"
     gene            2419..3192
                     /locus_tag="VXE36_001971"
     CDS             2419..3192
                     /locus_tag="VXE36_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0780204.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYDWKIEKELNSIEVINLMGNHDVYYLLGEQVPFSIQNLEVFFAV
                     QQLLQDLNLQVAYQLDDYLVSHAGFNLLFDPKEWHFKPFTEEYEEELEILANAVGYMR
                     GGGDMAGSPLWAHFRELELIPNNNYPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTDWATDQTLKQLPKPQI"
     gene            3364..4158
                     /locus_tag="VXE36_001972"
     CDS             3364..4158
                     /locus_tag="VXE36_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEV0780205.1"
                     /translation="MSYNRKIIRTSSYLEIWEYESPIFSNDTTQIDEEHISLKEKKKR
                     RTFEELTTAEQDERIKRISNTRKNSKWKLQRLIDTNFDDRTSFLTLTTKENIQNRYEF
                     NLLFDKFIKRLNYHIYHSKKRLIKYIAVLERQKRGAWHAHILLFSFPFIPHKELLTIW
                     GLGAVRINKLNDLDDSSNAGRYVAKYMEKGIGQELLESLGKKAFYSSRNLQKPEEIKL
                     FTSESLDNLVKNEDILYESNYISKVFRKGHLIDNKVKYKKIKLNKE"
     gene            4166..4435
                     /locus_tag="VXE36_001973"
     CDS             4166..4435
                     /locus_tag="VXE36_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0780206.1"
                     /translation="MQVILPTEQVQEIQSMITNLLQNEISHFKEDLGLDSPYLNKGQT
                     CKYLGISNNTLDGWIQKGLPVIKIGKTVRFNKNEIDKWLCRKAML"
     gene            4477..5697
                     /locus_tag="VXE36_001974"
     CDS             4477..5697
                     /locus_tag="VXE36_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014619928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0780207.1"
                     /translation="MSVTKTNSNTYNLKVYIPKEIRPKMGIKGNHFVKRYKTRKEAKE
                     AELEILTKIHQLENGEDIPLPKTSDILFSEFFNNIWWDSYKAGQTTSTTKPPTQATID
                     NTETVFRKHILPMFGNYSINFLNQNKQVVLNLMTAKAEEYANFKVIRSYVNSIFDWAE
                     ELEYIESNRLSKTIKRIKATKKLKLQESKNEEDLYLSSEELQDWFDAFREDLENDKLS
                     LKDYVLFFTTFILSDRKSESYALHWKNIDLANAQIDLRHALDKYKNVKSTKGNKKTIF
                     SIPSYLVSLLSEWKKQQKYELAKFGIMQTSDQLVFTYIDTKGNVNSPLHVDYLNNKMN
                     SVKRRHPKLKHATPHKLRHTGATLAKKAGMSLEAISEALTHSDTITTKTYVNTSNIVP
                     LSAGQVAYQHLKNK"
BASE COUNT         2244 a          924 c          946 g         1798 t
ORIGIN      
        1 ctcctgcttt tattcaaatc ttatgtattg tctttggtgt tctagcaatc tataaaataa
       61 ataataaatt aaaagatttt agatacgaac tagattttga tttaattatc agggaaagct
      121 tactatttgg tttatataca aatcatctct acacttcgga aaaggataat tcaggttacg
      181 aagaaattat tagaagtgcg attttaaaat atgaattaga taatcaaaac ggtcgtatta
      241 tcattaaagc gcttatcaga ggtgacgaat ttagtaaaaa ggttcagaca cttgacgatg
      301 tattagctgg agttctagaa cttgaactag aagaaaaaat tactcatcct aatattgtgg
      361 aatatcactt ttattacaag aaacctgata gactaatatt atcaccccat gatcataaaa
      421 aagagataga tagtcttgat atagacttag gatatgatat aacttataat cctataaaat
      481 gccctcatat tttagtttca ggtggtacag gtagcggaaa atctatattt atatctttct
      541 taattattga acttcttaaa agaaattcaa cactatatat tgcagatcct aagaacagtg
      601 atttaggtag tttatctcat tatttaagcg ataaatatgt agctacaacc cccaatagta
      661 ttgctcgtat tgtacgttta gtagttgaac aaatgcaggc acgatatcaa accatgcgtg
      721 ataactttca ttacggatca aattttgccg accatggctt taaaccagta tggcttatat
      781 ttgatgaaat gggagcattt caagcttcag caacagataa aaaatctaaa gaagttatca
      841 ccgaagtaat ggacggtatc aaacaaatta tcctactagg gcgacaagca ggagtattta
      901 ttcttatatc tgctcaacaa atgagagctg aaactctaaa cactgatctt agagataatt
      961 taggactgag aatagcttta ggagcaaact caatagaggg ataccgcatg gtatttggca
     1021 cggccacacc tgataagttt aaatctattg aagaaaaagg agcaggatat ctttatatgc
     1081 agggctcagg gaaagaaaaa gctcaatatt gggaaagtcc ttatcttgat acaacgcaat
     1141 tcgattttat aaaagaacta caattatacg taacaaagtc aaaataattt caatagatat
     1201 ttttgcttaa attcaataga ttttcagcaa aaatatctat tcctcatcgc ttaagcgatg
     1261 acaaaaagaa acgaggtatt attatgaaaa ttaacgattt tcttaaacca gaattattgg
     1321 gaaataaatt cgtggcagta aaaggatata cagaagtttt ggacagagaa acaaataaac
     1381 ctgtagcact acgtcttaat gtttcaattc aagatgagga ttctgatttc tttatggaaa
     1441 tgatccagat aaaagttaat acgttatctc ctacggctac tcctcaatta ttatcagata
     1501 aaaaaacatg ccccattaaa ttatctaatt taacagttgg acaatttaac ggaaatttat
     1561 ggttttcttg taacgatgta gtccctattt ctaaataatt cggtgatact atttatggct
     1621 aaactttttg caatatctga tatacatggg cactacaatg agtttattaa atctctcaat
     1681 aaaatagatt tatctgataa acaaagtaaa cttatcttac ttggagacta tattgacaat
     1741 ggacatcaat cttttcaagt tatttccaaa ataattgaac ttgaggaact tcatcctaat
     1801 caaattatta ctcttttagg aaatcacgaa gaatggtttt atgattggtt gattttagaa
     1861 aatcctactt cttcttcatt ttcggaaaca ataaaaagtt tcttctctcc agaggaattg
     1921 acctatattt taaaatctaa tgttaacaac tttgaagcag gtgttagaaa tgaaattaaa
     1981 aataatatca agttcaaccc attcataaac tggtttaaaa aacgatatag ggataaacgc
     2041 tattatgaaa ctgataccca aatttttgtt catgctggta ttgatgaaga agctggcaag
     2101 ctttggaaag acctaacgag ttcagagatg tttacaaata aatttcctct taccactggt
     2161 gaatttttta aagatattgt ttctggtcat gttgcttctt gggaagtagc taaagataaa
     2221 gcttaccaag gtaagattta ccatgatagt aaaagtcatt actttatcga tggagatgta
     2281 aagaatagca aaacaatacc tgttatctgc tatgatacag ttacaaaatc ctatcaatat
     2341 taaataacat cctaaaaaaa attggcagaa tttaactcta ttcttagact aatatcaaaa
     2401 ataaagaggg gaatctatat gaagacatta ttaattggcg acttacattt aaaatctcaa
     2461 ctaattttac ctattgttga caagattata caaacacata atattaaaag aatcattttt
     2521 cttggtgatt atgttgattt acatggacaa actaacaata tccaactata tgccaaagat
     2581 ctcacttttc tatacgattg gaaaatagaa aaagaattaa attcaataga agttattaac
     2641 cttatgggca atcacgatgt ttattattta cttggagaac aagttccttt ctcaattcaa
     2701 aatctagagg tctttttcgc agttcaacaa ttattacaag atttgaattt acaagtagct
     2761 tatcaactag atgattattt agttagccat gctggtttca atttgctatt tgacccaaaa
     2821 gaatggcact ttaaaccttt tactgaagaa tatgaagaag aattagaaat ccttgctaat
     2881 gcagtaggat atatgcgtgg aggaggagat atggctggtt ctcctttatg ggctcatttt
     2941 agagaactag agctaatccc taataacaac taccctaaac aaattgttgg acatacccct
     3001 aaagaatcta tcgatatttc taaaaatgtt attggtatag atactttttc attatatatt
     3061 gacaaagata ataaatatca atttattggt aacggagatt tgctcgttta tgaccaagga
     3121 catcttgaaa tcatttcaac tgactgggct acagaccaaa cattaaaaca attacctaaa
     3181 cctcaaattt aactactact tctcatcatg tgactaagcg aaactgccga ctggaagtcg
     3241 gcaagctgga agcgtgttta gcatagcgat gcttagaaac acatgataga agtatggagg
     3301 agctttgctt ctcctagttt atttattata taagcaaaca ttacgagaaa aggagatgat
     3361 tttgtgagtt acaatcgcaa aattatccga acttcttcgt accttgaaat atgggaatac
     3421 gaatctccaa ttttttcaaa tgatactact caaattgatg aagaacacat ttcactaaaa
     3481 gaaaagaaga aacgtagaac ttttgaagaa ctcacaactg ctgaacaaga tgaacgaata
     3541 aaaagaattt ctaacactcg taaaaattct aaatggaaac ttcaacgcct aatagataca
     3601 aattttgatg acagaactag tttccttacc cttacaacca aagaaaatat acaaaacaga
     3661 tatgagttta atttactttt tgataaattt attaaacgtt taaactatca catataccat
     3721 tccaaaaaaa gacttattaa atatattgca gtattagaac gacaaaaaag gggagcgtgg
     3781 catgcacaca ttctcctttt ttcatttcct tttatccctc ataaagaatt actaacaatt
     3841 tgggggttag gtgcagttcg gataaacaaa ctaaatgact tagatgattc ttctaatgct
     3901 ggtcgttatg ttgcaaaata tatggaaaaa ggcataggac aggaattatt agagagtcta
     3961 ggaaagaagg ctttttattc ttctcgtaat ttacaaaagc ctgaagaaat aaaattattt
     4021 acaagtgaat ccttagataa ccttgttaag aatgaagata tcctatatga aagcaactat
     4081 attagcaaag tatttcgaaa aggacactta attgacaata aagtaaaata caaaaaaata
     4141 aagttaaata aggagtaagg aaaaaatgca agttattcta ccaacagaac aagttcaaga
     4201 aatacagtcg atgatcacta atctcttgca aaatgaaatt tctcatttca aagaagattt
     4261 aggtttagat agtccttacc ttaacaaggg gcaaacttgc aaatatctag ggatatctaa
     4321 caatacatta gatggctgga tacaaaaggg gctacccgtt attaaaattg gtaagactgt
     4381 ccgtttcaat aaaaatgaga ttgataaatg gctttgtaga aaagctatgc tataatatct
     4441 ctaatgatat atcctgactc gtaaaaggaa aacatcatgt cagttacaaa aacaaatagt
     4501 aacacttaca atcttaaagt gtatatacct aaagaaatcc gacctaaaat ggggattaaa
     4561 ggaaatcact ttgttaaacg ctataaaaca agaaaggagg ctaaagaagc tgaattagaa
     4621 attctaacaa agatacatca acttgaaaat ggagaggata tcccactccc taaaactagt
     4681 gatattcttt tctctgagtt ctttaataat atttggtggg attcatacaa agctggtcaa
     4741 acaacttcaa caactaagcc tccaacacag gctactatcg ataatactga aactgttttc
     4801 agaaagcata ttttaccaat gttcggtaat tattcaatca attttctgaa tcagaataag
     4861 caagtcgtac taaacttaat gactgctaaa gctgaagagt atgctaattt caaagttatt
     4921 cgaagctatg taaactcaat tttcgattgg gctgaggaat tggagtacat agaatcaaat
     4981 cgattatcca agacaattaa acgaattaaa gctaccaaaa agctaaaact ccaagaatcc
     5041 aaaaatgagg aagacttgta tctatctagt gaagaattac aagattggtt tgatgctttt
     5101 agagaagatt tggagaacga taaattatca ctaaaagatt atgtcctatt ctttacaacc
     5161 tttattttga gcgatagaaa atcagaatcc tatgctttac attggaaaaa catagacttg
     5221 gcaaatgctc aaattgactt aaggcatgca cttgacaaat ataagaatgt aaagtcaaca
     5281 aaaggaaata agaaaacgat tttttcaatt cctagttacc ttgtatcact tctttcagaa
     5341 tggaaaaaac aacagaaata tgagttagcg aaatttggta taatgcaaac atccgatcaa
     5401 ctagtcttta cctatataga tacgaaaggt aatgtaaata gccctctaca cgttgattat
     5461 ctcaataaca aaatgaactc cgtaaaaaga cgacacccaa agttaaaaca cgctacacct
     5521 cataaattac gacatacagg agcgacactt gctaaaaaag caggaatgag cttagaagcc
     5581 atttctgaag cattaactca tagcgataca attacaacga agacttatgt taatacttca
     5641 aacatagttc cattatctgc tggacaagtt gcctaccaac atcttaaaaa caagtagaga
     5701 aaatttaggg caaattttag ggcaaacttt tgtagaaagt atagaaaaaa gcacccatag
     5761 ggcaaacctg tgagtgcttc gaaacgttga tataatcgag ttgattaacg ttttgaggca
     5821 actgaccatg tcaggttgca gccacatttg taagcgacta aagtcgcaac aactgtgtca
     5881 attgcaccaa tttagtaaga aagtataaaa aa
//
LOCUS       DAVLHB010000075         5439 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLHB010000075 DAVLHB010000000
VERSION     DAVLHB010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.075"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            12..1766
                     /locus_tag="VXE36_001975"
     CDS             12..1766
                     /locus_tag="VXE36_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780208.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVAFANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1750..3471
                     /locus_tag="VXE36_001976"
     CDS             1750..3471
                     /locus_tag="VXE36_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780209.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3482..4066
                     /locus_tag="VXE36_001977"
     CDS             3482..4066
                     /locus_tag="VXE36_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0780210.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            4066..4761
                     /locus_tag="VXE36_001978"
     CDS             4066..4761
                     /locus_tag="VXE36_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0780211.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFIA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPFKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4749..>5439
                     /locus_tag="VXE36_001979"
     CDS             4749..>5439
                     /locus_tag="VXE36_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780212.1"
                     /translation="MVEIKNLSLDYGEERILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLD"
BASE COUNT         1943 a          715 c         1020 g         1761 t
ORIGIN      
        1 gagatatgct tatgaagatt tacaaaaaac tatttgctta tgtccaagat aagaaatatc
       61 ttggggtttt ggccataatt ttttctgcta tatctgctct acttacagta tatggatatt
      121 atttaatcta caaatttcta gataagttaa taattaattc aaatttatcc ggtgcagaga
      181 gtatagcatt aaaatctgtt attacactaa caagtggagc gatattttat tttgtctcag
      241 gaatgttttc acatatcttg ggattcaggc ttgaaacaaa tttaagaaaa aggggaatcg
      301 atggtctgga aaaagcaagt tttaggttct ttgacttaaa tccatctggt caaataagaa
      361 agatcataga tgataatgca gcacaaactc atcaggtggt agcacacatg attcccgata
      421 gttctcaggc aataatcaca cccgtacttg tacttgcact tggctttata gtaagtataa
      481 gagttggcat aattttgctt gctcttacta taattggtgg cttaatttta ggggcgatga
      541 tgggcgagca agaatttatg aagatatacc aagaatccct atctaaacta agtgctgaaa
      601 ctgttgagta cgtgagagga atgcaagttg taaaaatatt taaagcaaat gtagagtcat
      661 ttaaaagctt ttacaaggct ataaaagatt actcaaagta tgcttatgat tattccctat
      721 cttgtaaaag gccttatgtt ttgtatcaat ggttattttt tggactgatt gcaattttaa
      781 ttattcctat agtttatttt atgactagct tagctagcgc aaaggtgatt ttacttgagc
      841 ttatcatgat tttattttta tcaggagttc tctttgtttc attcatgaga atgatgtggt
      901 actccatgta tatttctcaa ggaaattatg cagtagatac tttagaggcg ctttacgaag
      961 atatgcaaaa agacaaatta gtgcatggta atgtcaataa ttttaaaaac tataatatag
     1021 aatttgagaa tgttagcttt gcttataatg ataaagctgt cattgaaaat ttatccttta
     1081 atttagaaga aggaaagtcc tacgcacttg tcggttcatc tggatcaggc aaatcaacag
     1141 tagcaaaact tatatcaggt ttttataatg ttaataaagg aagcataaag ataggcggga
     1201 tagcaataag tgaatattct gacgaagcct taattaaagc catttccttt gtttttcaag
     1261 attcaaaatt attcaagaag agcatttatg ataatgtagc tttcgctaat aaagatgcga
     1321 cgaaagatga cgttatgaga gccttaaaat tagcaggatg cgatttaata ttagacaaat
     1381 tcccagaaag agaaaataca atcataggct caaaaggtgt ttatttatcc ggtggagaaa
     1441 aacaaagaat tgcaattgct agagcaattt taaaagattc caaaattatt attatggatg
     1501 aagcatcagc atctattgac ccagataacg agtttgaatt gcaaaaagct tttaaaaatc
     1561 ttatgaagga taaaacagtt atcatgattg cacacaggct atctacaatt aaagaccttg
     1621 atgaaattat tgtcatggat agtggaaaaa ttatagaaag agggtctgac aaagaattaa
     1681 tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt taacagtgcg aatgaatgga
     1741 gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc ttacagatgg aggagcaaga
     1801 aatttaagta aagcaacact ggcttcattt ttcgtttatt gtataaacat gcttcctgcc
     1861 atattactta tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag caatggcttt
     1921 tatatagtat tctcagtttt gactttgata gcaatgtata ttttgctttc tatcgaatac
     1981 gataaattat ataacacaac ctatcaagaa agtgcagatt taagaataag gacagcggag
     2041 aatttatcaa aattacctct atcttacttt tctaaacatg acatttccga catttcacaa
     2101 acaatcatgg ctgatattga aggcatagag catgcaatga gccactcaat accaaaggtg
     2161 ggcggcatgg tactgttttt cccattaata tctgtaatga tgctagcggg caatgtcaag
     2221 atgggtttag ctgtaattat tccatctatt ttaagcttta tatttatacc tttatctaaa
     2281 aaatatcagg ttaatggaca gaatagatat tatgatgtct taagaaaaaa ctcagaaagc
     2341 tttcaagaaa atatcgaaat gcaaatggag attaaagcat ataatttatc gaaggatatt
     2401 aaagatgact tatataaaaa aatggaagat agtgagagag tacacttaaa ggcggaagta
     2461 actacaattt taactttgtc tatatcttca atatttagct ttatatctct tgctgttgtg
     2521 atatttgtcg gcgtaaatct aattattaat aaagagataa attctctcta ccttatagga
     2581 tatttactag ctgctatgaa gataaaagac tctttagatg catctaaaga gggcttgatg
     2641 gaaatatttt atttatcgcc caaaatagaa agattaaaag aaattcaaaa tcaagattta
     2701 caagaaggcg atgactatag cttaaaaaaa tttgatattg atctaaaaga tgttgagttt
     2761 gcctacaata aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa gcagggagag
     2821 gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa acttatatca
     2881 agactttatg attatgacaa gggacaaatc ttaatcgatg gcaaagatat aaaagaaata
     2941 tcaacagaat ctctttttga taaggtctct atagttttcc aagatgtggt tctctttaat
     3001 caaagcgtta tggaaaatat tagaatcgga aagcaagatg caagtgacga agaggttaaa
     3061 agagcagcaa aacttgcaaa ttgcacagat tttatagaaa aaatggataa aggtttcgat
     3121 acagttattg gtgagaacgg agctgagcta tcaggaggag aaagacaaag attatcaata
     3181 gccagagcct tcttaaaaga tgcgccgata ttgatcttag atgagataac agcaagcctt
     3241 gatgttaaca acgagaaaaa gattcaagag tctttaaata atttagttaa agataaaact
     3301 gttgtaatca tttcacatag aatgaaatcc atagaaaatg cagacaagat agtagttctt
     3361 caaaacggaa gagtagaaag cgaaggtaag catgaagagc ttttacaaaa atcaaaaatt
     3421 tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat ttatttatta ggaggactac
     3481 aatggataat aaaaaattaa aagtaaaaga tttagtaagc atcggtgttt ttggcgtaat
     3541 ttattttgcc ttcatgtttg gagttggtat gatgggcttg attccaatat tgttcttaat
     3601 atacccgaca gtattagcca tagttgcagg aactgttgtt atgttattta tggctaaggt
     3661 tcaaaagcca tgggcactat ttatatttgg tatgatatca ccacttgtga tgtttgcagc
     3721 tggtcatacc tacgtagttg tggttttatc acttatagta atgataatag cagaattaat
     3781 tagaaagatt ggtaattata attcatttaa atacaatatg ctttcttatg caatcttcag
     3841 cacatggata tgtagctctt taatgcaaat gcttttagca aaagaaaaat atatggagtg
     3901 gtctttgatg acgatgggaa aagattatgt tgatgtgtta gaaaagttaa taacttatcc
     3961 tcatatggct ttagtagcct taggtgcttt cttaggagga attcttggag catatatagg
     4021 caaggctcta ttgaaaaaac actttgaaaa agcaggcatt gtataatgcc tactttttct
     4081 tcaaatgctc cctttaatcc caatccgatc tctaagatat tagtcgtatt tatcacaggc
     4141 ttaactgtta tgcatagcat aaacatccgt tttgagctgg caattgtttg tcttattggt
     4201 attttgcttt atttgaatgg atacaaaaaa acacttttca aatggattat attgtgtggg
     4261 atactttact ccttgcctaa ttttatggtg ttatctgaat taaaccctat agttaagatg
     4321 tttttgagta tacctattgt tattagaatg tttattttac catttatagc agcaagcttt
     4381 atgataaaga cctcggatgt aggcgcaata atttcatcga tggataagct taagatttca
     4441 aagaatgtat ccatacctat tgcggttatg tttagattct tcccatcttt taaggaggag
     4501 aagaaaaaca tcaaaatggc tatgagagta agagggataa gttttaaaaa cccattcaaa
     4561 tatcttgaat atgtttctat gccactactc attatatcat ctaatatatc agatgacatt
     4621 gcaaaagcgg cagaaacaaa ggcaatagaa aatccaattg ccaagaccag atacattcgc
     4681 gtaaagatac agctaattga ttttgtttat gttttagcgg ttgctggact tattgtggga
     4741 ggcttaatat ggttgaaata aaaaatttaa gtcttgatta tggtgaagag cgtatattag
     4801 atgatatatc actatccata gccgagggag agtgcgtgct atttacagga aaaagtggaa
     4861 atggtaagtc atctttaata aattcaatca atggactagc tgtaaggtat gataacgcaa
     4921 agacaaaggg cgaaataatt attgatggta agaatataaa aaatttggaa ctttatcaaa
     4981 tctcaatgct tgtttcaact gtttttcaaa atcctaagac ctattttttt aatgtcaata
     5041 cgacattaga attattattt tatttggaaa atatcggtct tgcaagagaa gagatggaca
     5101 ggcgtttgaa ggatatgctt aagatattcc cgataaaaaa tcttttgaac agaaatatat
     5161 ttaatctatc cggcggtgaa aaacaaattc tttgcattgc agcttcttat atagcaggta
     5221 caaagattat agttatggat gagccttcat cgaatttaga tattaaaagc ataagtgttt
     5281 tggcaaagat gctaaagata ttaaaagaga aaggtataag cataattgtt gcagagcata
     5341 gaatttatta tttgatggac atagttgacc gtgtattttt aatagataaa ggaaagctta
     5401 aaaaaactta tactagaagt gaatttttaa agctagata
//
LOCUS       DAVLHB010000076         5263 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLHB010000076 DAVLHB010000000
VERSION     DAVLHB010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.076"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(409..1137)
                     /locus_tag="VXE36_001980"
     CDS             complement(409..1137)
                     /locus_tag="VXE36_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0780213.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1295..2704
                     /locus_tag="VXE36_001981"
     CDS             1295..2704
                     /locus_tag="VXE36_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0780214.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQIIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2722..4017
                     /locus_tag="VXE36_001982"
     CDS             2722..4017
                     /locus_tag="VXE36_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0780215.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            4022..4330
                     /locus_tag="VXE36_001983"
     CDS             4022..4330
                     /locus_tag="VXE36_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0780216.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4327..4635
                     /locus_tag="VXE36_001984"
     CDS             4327..4635
                     /locus_tag="VXE36_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0780217.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1776 a          879 c          959 g         1649 t
ORIGIN      
        1 tgattcagaa tttatttaat atattaaaag aagatatgaa caaataaatt gggagattga
       61 aattcatttc tagcaatttt ttagaagtca cagtctacta ttctaacctc agtatactat
      121 atgtgttaca agaaaagact caaaaacttc tcgtcagtgt aagaatgttt gaaacactat
      181 ttaaaactaa ataactataa gaagtagatc aggtgaacaa tttcagtacc tactctataa
      241 gctatacgaa gatatttttc aacatgatgg ataaaacgat cactctttta aagccatctt
      301 atttagaaaa gagaaaccat ttaagcatag atgggacctt cttgccctgt tttaaatttt
      361 tcttaaacta gagtctgtaa aagattggct tcattttcac attttctcct aggaggaatg
      421 tcgtaatgca aaagaattaa attcaaataa atcatagcga tgacgactaa tcgagtactc
      481 aaacggagtt ccgttatcca aataagccac ttgttctact tcaaataccg gttccgttgg
      541 aaggagctgc aagtaatgtt gctcattttc tgaactagaa gaagctcgca agatttttgt
      601 agcactggca atatgcaatc ctaactttcc ttcaatgtaa ttgtaaatcg atttttgtaa
      661 aatatcttca gtaatacctg gaataacatc ggtactcata taagtttgtt ccagaacata
      721 aggtttaccg tcaataatac gcaggcggta aatattataa actggactct gcaaagcgac
      781 ctgtagtttt tctgctaaaa attcatttgc aaattctaat ttgaagtgaa taatcctcga
      841 gtcaattgta gaatgagcat cttcagatat ttttgtcagt ccccggatat ctctttctgg
      901 aacgattaat tttctttttg agctgccacg agagagaaca aaggttccct gcccacgttt
      961 tctaaaaatt aagccctcag aaactaacaa gtctaaagct tttttgatcg tcattcgact
     1021 acaggcaaac tgtttagcta atgtcatttc atcaggcaat tgttcgttca tggtatattt
     1081 attacaaaga atcttttcac gaatctcatt gtaaataaat aaatattttg tactcattta
     1141 atctggttct ctctataata ttctaatagt agtataacaa agttcaagaa atgaggcaaa
     1201 cacaagatat gtataaacaa tttttaaaaa tgtctagaca aattttaaaa ttatgctata
     1261 ctttatgtat agaataatag aaaggaggtt gagcatgaaa aaaaagttag tatttcctaa
     1321 tctgttttgg tggggggctg cttctagcgg acctcagaca gaaggtcaat atggaaaagt
     1381 acatgaaaat gtgatggact actggttcaa aacgcatcca gaagattttt tcgataatgt
     1441 cggacctctt gtagccagta acttttttca tacttacacc gaagatttcc acttgatgaa
     1501 ggaaattgga gttaattctt tccgcacttc catccaatgg agtcgactca tcaagaattt
     1561 agagacaggt gagcctgatc caaaaggtat tgctttctac aatgccatca ttgaagaagc
     1621 taaaaagaac cagatggatc ttgtgatgaa tttacatcat tttgatttac cagtggaact
     1681 tcttcaaaaa tacggtggtt gggaaagcaa acatgtagtg gagttattcg tgaagtttgc
     1741 caagactgct ttcacatgct ttggagataa ggttcattac tggacaactt tcaatgagcc
     1801 aatggtcatt ccagaagcag gatacttata tgctttccat tatccaaatc taaaaggaaa
     1861 gggaaaagag gccgtacaaa tcatctataa tctaaacctt gctagtgcaa aagtgattca
     1921 actatatcgc tcattaggac ttgatggaaa gattgggatt attttaaact tgacacctgc
     1981 ttatccaaga agtaattctc cagaagactt agaagcaagt cgatttacag atgacttctt
     2041 taacaaagtc ttcttgaatc cagctgttaa aggaactttc ccagaaagat tggtaaaaca
     2101 gctagagaga gatggcgtgt tatggagtca taccgaaaaa gagcttcaac tgatgaaatc
     2161 aaatacggtt gattttcttg gagtaaacta ctaccatcca aaacgtgttc aagcacaagc
     2221 aaatcctgag gaatatcaga cgccctggat gccagaccaa tacttcaaag agtatgaatg
     2281 gccggagcgt cgcatgaatc catatcgtgg ttgggaaatt tttccgaaag ccatttatga
     2341 tattgctatg attgtgaagg aagaatatga taatattcca tggtttatca gtgaaaacgg
     2401 aatgggtgtt gaaaacgaag cacggtttat cggtgaaaat ggagttatcg atgacgtgta
     2461 tcgtattgaa ttttatgaag aacatttaag atggctacat aaagccattg aagagggaag
     2521 tcactgtttt ggataccacg cttggaccgc atttgattgc tggtcttgga ataatgcata
     2581 taagaatcgt tacggattta tctccgttga tttagaaacg caaaagagaa ccatcaagag
     2641 ctcaggaaga tggtatcgca aagtaagtga caataacggt tttgaagtag aaattgagga
     2701 gtaaagagag gagatattca gatgaaaaac tcaaaattta tagatcaatt tgccaccttt
     2761 gctggtaaac tagggaacca aattcattta aaaaccctaa gagatgcatt cgtaacagta
     2821 atgccattat atattttggc aggtttaatc gttcttttga acaacacggt atttaagtgg
     2881 attttccaag gggatacatt aacaagattc caatattggg gaataacaat tgcaaacggt
     2941 actttaagta tttcaggtat gattattgct gtaatggttg gttatttctt agctaaaaac
     3001 agagatttcg aaaacccgtt agcagcatca atgctatcat tagtttcttt aattgtgatg
     3061 atgccaaata cagtttctgt agttcctgac ggagcaaaag atgcggtaaa catttcaggt
     3121 gttctttcat tcaacaacac aggtacaggc gcaatgttcg ccggggttat cgtagcgatt
     3181 attgcaacag aattattcat tgaattatca aacgttaaag ctttacaaat gaaccttggt
     3241 gaaaatattc caccagctgt tagtagatca tttagcgtat tacttccagt catgaccgtc
     3301 atctccttat ttggggttgt ttcagcatta ttattcaata taactggaat gaacttaatc
     3361 tcaatcatta caatctttat tcaagaacca attcgtcata ttggtacaag cttaatcggg
     3421 gtcattatta tttactcttt aggaaatatg ttatggctat ttggtattca ccaagcagtt
     3481 atttacagtg ccatcctaga accattacta ttaattaaca ttactgaaaa catcactgca
     3541 gcaaataatg gacaagccat tccacacatc atcaacctat cacaaataca aacattcgct
     3601 ttaatgggtg gtagtggatc tacattatgt ttattaatag caacattctt agtgagtcgc
     3661 aatgctgtct ctaaaaacgt ggctaaatta tcttttggac ctggtatctt caatatcaat
     3721 gaaccagtat tattcggtta cccaatcgtt tataacattt cattagctat tccatttatc
     3781 acagttccag tccttggtat tttaatcagc tacttagcaa cagttacagg attcatgagt
     3841 cctgcattta tacaagttcc ttggactaca ccagtattct taaatgcatg gttagcaaca
     3901 gcaggggacg tgagagcagt tctagttcaa ttcatcatct ttgcacttgg agttcttcta
     3961 tacattccat ttatcaaagt taatgacaaa gttgttgagc aagaaatgga aggttaagat
     4021 tatgaaacaa attttattag tatgtaatgc gggaatgtcg acaagtatgc ttgttaaaaa
     4081 aatgcaacaa agtgcgactg aacgtgggat tgaaatttct atccaagcaa aatcaatgac
     4141 agaagctaaa aagaatatcc atgaagcaga tgtcattcta attgggccac aaattcgtta
     4201 tgagttactt gctgtgaaag aaattgcagg aaatatccct gtagatacca ttgatatgcg
     4261 ggattacgga atgatgaatg gagcaaaagt tctggaacaa gcacttgcat ggataggaga
     4321 aataagatga cagaagaaat ggaatatatc tgttttcagc tcattgccaa tagtggagca
     4381 gccaaatcat cctttattga agccatccaa ctagctaagg caggaaattt aaaagaagcg
     4441 aaaattaaag ttgaagaagc ggaagactcc ttagtagaag cgcacaagat tcactctaat
     4501 ctcatacaaa aagaagctac tggagaaaaa ataggattct ccttgctatt tatgcatgca
     4561 gaagaccaaa tggcttcaac agagattatt cagttgctat ctaaagaatt catcgatctc
     4621 tatcaaaata aataggaaca ctgtcgttcc catctgtctt tattaatgac ggctacattg
     4681 taggaacctc caaaagttgg acaaaatgat tgaaaggatt ggatcctgca ttacacaaga
     4741 tccaatcctt ttcttttact ctagttttta taatgtgttg aatttagaat agtccactgc
     4801 agtttctaaa aaattgctgg aaatagatgt taagctccaa tttatttgtt tatatcttat
     4861 ttcagtttac tatactagct tattattcta gtaaaaaatt gaatgagcca ctatttattt
     4921 aatatgtatg atgagggaat gactcaaaaa cttcttgtcg atataagaat atctgagata
     4981 gtattttaaa acgaaaggac tataaaagct catttccttc gcacttattt tatagagatc
     5041 tatcattata ctctttagaa atcaaaaagc aacacacctt gtcatcgttt tatcgtaaat
     5101 ctgttaatga gggggctagt cttatctgca atctcaaatc agtgttttga gctgaatggc
     5161 actcgttttc tagtttgctc tttgatttta attgggcctt agtaaatact actcttaaat
     5221 taaactatag tgaattgaaa taagatgtga acaactctat cag
//
LOCUS       DAVLHB010000077         5223 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLHB010000077 DAVLHB010000000
VERSION     DAVLHB010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.077"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(116..574)
                     /locus_tag="VXE36_001985"
     CDS             complement(116..574)
                     /locus_tag="VXE36_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0780218.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(571..1011)
                     /locus_tag="VXE36_001986"
     CDS             complement(571..1011)
                     /locus_tag="VXE36_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0780219.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1444..2310
                     /locus_tag="VXE36_001987"
     CDS             1444..2310
                     /locus_tag="VXE36_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0780220.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGGLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            2636..3193
                     /locus_tag="VXE36_001988"
     CDS             2636..3193
                     /locus_tag="VXE36_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HEV0780221.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            3414..4520
                     /locus_tag="VXE36_001989"
     CDS             3414..4520
                     /locus_tag="VXE36_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEV0780222.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLYFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            4496..>5223
                     /locus_tag="VXE36_001990"
     CDS             4496..>5223
                     /locus_tag="VXE36_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780223.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDIS"
BASE COUNT         1831 a          680 c         1003 g         1709 t
ORIGIN      
        1 atttgactgt cctgatcgat ttatcctgtt cttatttcat ttcactatag taaggtgcag
       61 caggataaag aaaaaccgag aagtttcttt ctcggatttg cttattatga ggttcctatt
      121 ttctatgctc caagagttga ttgatgtgat ctactttttt agcctctctt ttatagagaa
      181 tagcccagat gatgagatag acaatcgcaa actcgataat gagctggagg tagaaaatcc
      241 agtggaaagg gaaccaacca gcaagagttg ctagtgggac aaagccagcc agcataagga
      301 agaaatgagt cagagtggca cgaagcatgc tccagtcacg gctaaataag cggttgccaa
      361 agttgaagag cataccgatg gttgcccaga taagtgtgca gtagagcaag accagggcac
      421 cgtgaacctg atgctgatcc atcacttggc cgatgagaga gtagggattt agtggtgcgt
      481 aggtatttgg tgcataaatg agtgaaaaga ggatagagag gatgaggccg ataagaacac
      541 cggtagctgc atcgtgaaat acttgttttt tcatagttct aatttctcct tgatggtttt
      601 tagataacgg cgtgaagagt aggtgaagct ttcgtttttc aagaaaattt ctaccagacc
      661 gtttggcgtg agcttgaggt gagagatgga atcgatattg atgatttctg attgggaaat
      721 ttggataaaa ttggttggca agagtttaag aacctgatag agtcgcaaat caatgctgta
      781 ggtctgactc gcggtttctg ctagaacctt ccgattctcg atatagaagc gctgaatctt
      841 gccaatctca actagataga cctgatcatc gatttttcct ttgatttttt ctctttggtc
      901 cagattttct gcgaactcga tgactttctg gactttttcg gtttcttgag gtgcttggac
      961 aatcagcttt tcctcctcgt aagtctcact aatctgtagt tctactttca tagttttctc
     1021 tccttttcag ttatacaagg ttgtgatcac ttcctgtata tccttattaa acactatttt
     1081 atagcccatg gcaaggaacc ttgtctatgt ggagggattg ggctcctatg tggtggagct
     1141 tttctgttct ttctgaaata tggtataata gcactaatca atttctagga aaatagatac
     1201 ggaaaggggc tgaaagaact aggggaacag ttggaattag aaagtgatag gtatgaaaag
     1261 tggcgttgaa gctgaataag tttataaagc gtttgaatga agaaatggaa agtaaataag
     1321 ttgacgatga attacaaaat agattttatc tacaatttgt atctttcaaa tcattgattt
     1381 gaattttaga tttaatcatg ttacaattaa aactgaaatc aaatagaaga ggaaaatgca
     1441 aacgtgggca cactattagc aacaagatta aaaaatagac ggaaagaatt aaaaatgtct
     1501 cagcgagaac tagctgaagg tatctgtaaa caggggcaaa tcagtcgatt agagagcgga
     1561 gagtttaccc ctggagcgga tttcctgaat gcccttgcta agaagttaaa agtcagtatg
     1621 gattattttt ttgatgagca ggttgtagag aaagttgagg agttatcaga atttaagaaa
     1681 ttagcacaga catttattac aaatcgcaat tatgagtctt tgaaatatat atatgaattg
     1741 gagaatgtaa aagctcaccg cctatcttta gcagataaaa tctacatgga atggataaaa
     1801 tctctgatag atttttattt ttacggacag aaagaagatg cgattgtacg attagagggg
     1861 ggattatcac agttaagtgt atctgatttg aactatctcc aagtttcaaa caccctattc
     1921 aatttttatt atgatattgg agatttaggt cgtttcaata aaattcgtga aaaactagag
     1981 tatcaagtaa atcacctcaa tttgagtaca atcgaagagt tagaactatc tattaagttt
     2041 aactacaacg tttgtcgtta tctatggtta cagaaaaata ttgaagaagc tattactaaa
     2101 attacagcta ctataaaaca atgtaaggct tacagaacga attatctttt ggctgatttg
     2161 tacttattga tgggaaatgt aagtgaaaat ttttcttcta aaagttcggt gaaagaatat
     2221 tttgagacgg catattttct atacaaactt gaggagaaca tgtcaatgac tctgaaagtt
     2281 gagcattaca ttgcagatat aacagaataa tgaatacggt gttcaagtga gcatcgtttt
     2341 tcaaacctag ttcagataca aaaaagtatc aaacaaaaaa aaataaaaaa acattataaa
     2401 aaaaattgac aagctaattt tgaagtgata aaataaatgc aagaaaacaa aaggagaggt
     2461 atatgagaag tttgtttaag aaaatagttg ctgtattagt tattggctta attctgttag
     2521 gaattgcgag aacacctcaa gttcataaga tggctagagg gattgatcct ggtcctgcga
     2581 attttattta gaaatcaatt tctactaatt gagtattaat gggtaaaaag attgtatgga
     2641 taagaaaaat ttacttgtat tggttactgg ttcggtaggt gccagtaatg tagatacata
     2701 cttatattat ataaaaaaat tctataatgt taaagtgata ctttctgaaa attctaaaaa
     2761 atttataagt aaggaattaa ttagttattt ttgtgataaa gtttatgatg aaatatttgt
     2821 tgaagaggta gttccgcacg tttttctgcc atatgaatct gacttacttc ttattttacc
     2881 agctacggca aatgtgattg gcaaaattgc taatggtatt gctgatgatt tagttacagc
     2941 aactgtttta aactttaata aaaaaataat tttttgtccc aatatgaact ctactatgtg
     3001 ggacaatcac atagttcaaa gaaatgtatc aattctaaag gagttgggac atatattttt
     3061 atttgagtct aaaaaaacat atgaggtagg attgcgtaaa gcaatagatt caacatgttc
     3121 aatgttacaa ccacagtcgt tagtaaaaga acttatcaaa ttagaaaata ttgtccttga
     3181 agagggacat taaaaactac tgagaatatt aatgagggga aaaaatggaa aattcatcaa
     3241 tcgatgtaga tatgctgttg gaagaattga cacaagaagc aatggtcgtt gttgctgttg
     3301 ataaggactg ttaatttaaa cttatggcaa tatatgaaag gttactggat gttttaaatt
     3361 atgcaggcag tagcctttta ttatatacaa atggataaag taaggataat acaatgatta
     3421 ataaaaaaat acaacaagtt gttttggaat cattacagaa ttttttgaat gggaacttca
     3481 tttcgccttg tgtagtctat gattttggct tgctggaaac tgtacttgat gaatttaaaa
     3541 atcaaattcc tgtaacattc aattaccaac ttttttatgc cgttaaagca aattcaaatg
     3601 agaagatact tgaattctta gtagataaaa ttgatggagt tgatgtggcg tcattatctg
     3661 aattagatgt ggctaaaaaa tttttcccac caactcaaat ttctgttaat ggtcccgcat
     3721 tttcttatga aactttatat aatctgatta aaaaacaata taaagttgat attaactttt
     3781 tggaacatct tcaacaattt tccccaaaag aatctgttgg aataagagta acggagccag
     3841 atgaacttaa taatcgtatg agtcgatttg gaataaatat ttgcagtgat aattggacta
     3901 gtaatttaca aaatccttta attacacgac tgtattttca ttttggagaa aaagatgata
     3961 aatttattgt taagttagat aaaatattat ttaagttaca agaaattaat aaacttagag
     4021 aggttagaga aataaatctt ggaggcggtt ttatgaaatt atttatggaa aatcgtttga
     4081 aagaattttt tctatcactt atggaaatct ataaaaagta cgatattgat agtactgtga
     4141 ctacaataat agaaccaggt agtgcaatta cttcattttc tgcctatatg attactagcc
     4201 cagttaatgt tagtgaggtg aatgagcagc aggttatcac gttagacaca tcaatataca
     4261 ccaatacatt atggtttgtt ccgcatatta ttacaacgtt aaattcaagt agtaaagagc
     4321 gttatagtac tattctctat ggtaatacct gttatgaaca tgacaagtat aaaatgaaag
     4381 tttcgcttcc aaggttaact caaaatagca gtatagtgtt ttttcctgta ggagcttata
     4441 taaaaagcaa tcattcaaat ttacatcgta atgattttat gcgggaggta tatttgtgga
     4501 caaaaaactt gacatattag ataaagttaa ggaatattta ggaaataaaa ctactcaaat
     4561 tctggataat caatataaag aatttttgaa acttaatgat ataaggcgag cgtttggtat
     4621 ttcagaaaaa gtattaaaca attcttttaa ttttacgagt aaagaattta atgatttaat
     4681 taataacgaa aattatttat tcgaatatgc atgtagaatt agagaggaat ggagaaaaaa
     4741 atgctttaat cattcttatc gttttctatg ctcacctata attacagatg attttcttaa
     4801 cacgaagaca ttgagaagta gccaaattga atataaatat gagcgatatt tatcgaaaag
     4861 ttcgataggc gatagagcgg ttgatggctt tgtttccttc aatactttaa cagctaatgg
     4921 tatgtctgct attaaactat gtcttgagat attaaactct attttcttca agaagaagat
     4981 tgatttatta tattcaaccg gatattatga aacaagattt ttattaaata atcttgctaa
     5041 atcaggtatt agttgctatg aggtaagtaa ttgtgaattg gataaagata aattttataa
     5101 tgtattcatg atggaaccca atcgagccga tttaacatta caaaaaactg atttcaagat
     5161 agtagaatat tttgttaagt ataaaaataa ttcaataaaa gtcgttattt tagatatttc
     5221 ata
//
LOCUS       DAVLHB010000078         5161 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLHB010000078 DAVLHB010000000
VERSION     DAVLHB010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.078"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            269..487
                     /locus_tag="VXE36_001991"
     CDS             269..487
                     /locus_tag="VXE36_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0780224.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            880..1905
                     /locus_tag="VXE36_001992"
     CDS             880..1905
                     /locus_tag="VXE36_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0780225.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1895..2902
                     /locus_tag="VXE36_001993"
     CDS             1895..2902
                     /locus_tag="VXE36_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0780226.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2902..3909
                     /locus_tag="VXE36_001994"
     CDS             2902..3909
                     /locus_tag="VXE36_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0780227.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3909..4703
                     /locus_tag="VXE36_001995"
     CDS             3909..4703
                     /locus_tag="VXE36_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780228.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT         1929 a          725 c          869 g         1638 t
ORIGIN      
        1 tctttaaaga gtcttatttt gtgatgaaaa tttaatatgt aaatctcaga cgatagaaat
       61 taaaaactct atcgtctttt ttatactcaa aattaggagg taaaaatggt aaggataaga
      121 ggtcccactt aaaacaattt atggcaaaat aaggacggaa taacacaaca aattctctaa
      181 aacaaatcac taaatcaatg taagattgaa tgaaatcaat atttatgcta taattaaata
      241 aatctaatga agaaaaaaga gggatattat ggcacttaac tataaaccat tatggataca
      301 gttagcaaaa aaaggactaa agaaaacaga tgtaatagct atggcaggac ttacaacaaa
      361 tgttatggca caaatgggaa aggataaacc aattacattt aagaatttag aaagaatatg
      421 taaggcttta tcttgcactc ctaatgatat tattagtttt gaagataatt ttagtgacga
      481 ggaatagaaa atgactttaa ggacagaaga tcaagttagg gattatgcaa gagaagtata
      541 ggctttaatg aagttgaaga aaacatcaat caaggtactg gtcaaataac tacttttaat
      601 caattaggct tcaagggata ttcagataag ccagatggtt ggtatttacc taaaaatatg
      661 aatgatgtag caataatcct tgaaacaaaa tcagaagaaa gagatattag caaacaaatt
      721 tttattgatg agttaatgaa aaatatagac ataatttaac taaaaataaa aactagatcc
      781 ttttttgaaa aaattatatt attaaatttg taactgtatc tattgacaat gataattatt
      841 atcgatacaa tagacttgaa atatgtttaa ggagttttta tgaaaaacaa attttttcta
      901 atagctattt tagctatgtg tatagttttt agcgcttgtt cttctaattc tgttaaaaat
      961 gaagaaaata cttctaaaga gcatgcgcct gataaaatag ttttagatca tgctttcggt
     1021 caaactatat tagataaaaa acctgaaaga gttgcaacta ttgcttgggg aaatcatgat
     1081 gtagcattag ctttaggaat agttcctgtt ggattttcaa aagcaaatta cggtgtaagt
     1141 gctgataaag gagttttacc atggacagaa gaaaaaatca aagaactaaa tggtaaagct
     1201 aacctatttg acgatttgga tggacttaac tttgaagcaa tatcaaattc taaaccagat
     1261 gttatcttag caggttattc tggtataact aaagaagatt atgacactct atcaaaaatt
     1321 gctcctgtag cagcatacaa atctaaacct tggcaaactt tatggagaga tatgattaaa
     1381 attgattcaa aagccttagg tatggaaaaa gaaggtgatg agttaatcaa aaatactgaa
     1441 gctcgtatat ccaaagaatt agaaaaacat ccagaaatca aaggaaaaat caaaggaaaa
     1501 aaagtattat ttactatgat taatgctgca gatacatcaa aattctggat ttatactagc
     1561 aaagatccaa gagcaaatta tttaacagat ttaggtctag ttttccctga atcattaaaa
     1621 gaatttgaga gtgaagatag ttttgcaaag gaaatttctg cagaagaagc aaataagata
     1681 aatgatgctg atgtaatcat aacttatggt gatgataaaa ctcttgaagc tttacaaaaa
     1741 gatcctcttt taggtaaaat aaatgcaatt aaaaatggtg ccgttgctgt aattccagat
     1801 aatacaccgt tagcagcctc atgcactcca acaccacttt caataaacta tactattgaa
     1861 gaatatctaa atcttttagg aaatgcatgc aaaaatgcga aataaaaaac aaataaacct
     1921 aggcataatt tttgtaatct gcctaggtct tcttattaca atatttttgt cattaaagct
     1981 tggaacaaaa gaaattaata tcagagattt tttagcagct tttggaatgg gtaatacaaa
     2041 tgatgatttt attaaatcaa ttatatataa aagaatacct agaactattt ttgcaatttt
     2101 agcaggttct agtcttgcca taagcggtgt attgatgcaa tcagttacta gaaacccaat
     2161 agctgatcca ggtatactcg gtataaacac aggagcaagt cttagtgtag taattggtct
     2221 ttctttttta ggaatttcat caagcataag ccatataagt tttgcaatca ttggtggctt
     2281 agtaagtgca atttttgtat acgcgattgc tgtaagcgga aaagcaggcc ttacccctat
     2341 aaaacttgcc ttatcaggaa cttgtgttag tatggcttta agcagttttg taagtttttt
     2401 aattttaccg aataataacg tcttagacaa atttagattt tggcaaatag gtagccttgg
     2461 agcagctaca ttatcttcta tatctacact actacctttt ataattttag gtcacttgat
     2521 agctatattt atttcatcag atttaaacgc tttagctatg ggtgatgaaa tggctgttgg
     2581 tcttggagtt aatgttaata ggataagatc acttgcaata attgcaagtg tgcttttatg
     2641 ttcaagtatt actgcaattg gtggacctat tggcttcgta ggtcttatag ttcctcactt
     2701 ttgtggctta tttataagca aagatatacg cacaatgacc atttcttcat cttttatagg
     2761 tgcagagctc ttgcttatat gtgatataat cggccgtatg ttaggtaaac caggtgaaat
     2821 tgaagtaggg ataattactg caataatcgg gggtccagta cttatttatg taactatgaa
     2881 aaatagaggg gttaataact aatgcaaaat ttaattatag gtattcaaaa aagaaaaaat
     2941 agaataacac tattttcctc actattttta ttaataataa tcagtctatc atttttcatt
     3001 ttacttatcg gagatgaaag ttattctttt tcaactttga ttaaagtctt aaatagtgaa
     3061 actgttcctg gagctagttt ttcgattatg gaaattagat taccaaaatt attagcagga
     3121 attatagctg gctggtcttt tggattggca ggatttatct ttcaaactat gttaagaaat
     3181 cctcttgcaa gtcctgatat aatcggtgtc acaagttctt catctattgc agcggtcttt
     3241 tgcatattgg tattaaaaac aaatagttta actactggaa ttatttcaat aacttgtgga
     3301 ctaacatcat ctttaatatt atttttacta gctaaaaaag atggtttttc agcagcaaga
     3361 ctgataatat taggtattgg ttttcaagct gtcacaagag caggcacctc atttttattg
     3421 ttgaaagtag caagatatga attacaagaa gttatgagat ggctcagtgg ctctttatct
     3481 tttacaaagt tagatgacat acctcttgtt ctaatagtaa gtattattgc tactatatta
     3541 gttttatttt ttaataaaag actagaaatt attgaacttg gtgaagaaat agcaatcgga
     3601 cttggagcaa atcccgagct ttcaaggctt gttttaattt tttgcgctgt atctttaact
     3661 gctttttcta cttcaattac aggaccaata gcttgtatat cttttttagc tggtcccata
     3721 gccttaaata ttggcaagaa aagaagccca atattagctg gattggttgg aattttacta
     3781 gttttgttat cagacatatt ctctcaaaat attttaccag ctagatatcc agtaggtgtt
     3841 gtaactggct tgttaggttc accatactta atatacttac taataaaaat gaacaggagg
     3901 aatatataat gaaaggtctg tggtcaaata atcttacctg cggttatgat gaaaaaataa
     3961 tcttggaaaa tataaatata aaaatacctg aagaaaaaat atcagttatt attgggtcaa
     4021 atggttgtgg gaaatcaaca ctcattaaaa ccttgtctcg acttataaag ccattagagg
     4081 gagaagtatt gcttgataat aaatcaatta attcttataa agaaaaagat ttagcaaaac
     4141 acatagctat attacctcaa tctccaataa tccctgaatc aataacagta gctgatcttg
     4201 taagccgtgg tcgtttcccc tacagaaagc cttttaagag tcttggaaaa gatgaccttg
     4261 aaataataaa cagatcaatg gttaaggcca atgttgaaga tctagcaaat aacctagttg
     4321 aagaactttc tgggggtcaa aggcaaagag tatggatagc tctagcccta gcccaagata
     4381 caagtatcct acttttagat gagccaacta cttacttgga tatctcatat caaatagaac
     4441 tattagacct cttgactgat ctaaaccaaa aatataagac aaccatttgc atgattttgc
     4501 acgatataaa tctaacagca agatacgctg attacctatt tgcaattaaa gaaggtaaac
     4561 ttgttgcaga gggaaagcct gaagatatac taaatgataa actagttaaa gatatcttta
     4621 atcttgaagc aaaaattata cgtgacccta tttccaattc gcctctaatg attcctattg
     4681 gcaagcacca tgttagctct taataattga atatcggaat tcatttaaaa gtcgcaaatt
     4741 ttgaactgac cctcaaaagt taggccaaaa aactaactaa aggaggtcag ttttttaatg
     4801 gcaaatacag cacagaattt aagataaaat tagtaaaaga atatcatgaa tgaaaaatag
     4861 gatatagaga ataacagcaa tattaaaaag atcaggactg ataataaaca aaaagaaagt
     4921 acaacgacta gttcaaaagc taaaacttca agtaaaaagt tattcaagaa aatctagaaa
     4981 atactcatcc tacaaaggac aggtaggaaa aatatcagac aacaaaataa aaagaaatat
     5041 ttattaccga aaaaaagggg aaatcgagtc aagtaccaac aggctcatct attccaaaaa
     5101 gatatttact cgatggaaaa actcctagaa ttagtgctac aaatattgac aatggtatct
     5161 t
//
LOCUS       DAVLHB010000079         5038 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLHB010000079 DAVLHB010000000
VERSION     DAVLHB010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.079"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(285..1511)
                     /locus_tag="VXE36_001996"
     CDS             complement(285..1511)
                     /locus_tag="VXE36_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0780229.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLVSDTLSAFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1583..2248)
                     /locus_tag="VXE36_001997"
     CDS             complement(1583..2248)
                     /locus_tag="VXE36_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0780230.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2316..2513)
                     /locus_tag="VXE36_001998"
     CDS             complement(2316..2513)
                     /locus_tag="VXE36_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0780231.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            complement(2804..3667)
                     /locus_tag="VXE36_001999"
     CDS             complement(2804..3667)
                     /locus_tag="VXE36_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0780232.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            complement(4063..>5038)
                     /locus_tag="VXE36_002000"
     CDS             complement(4063..>5038)
                     /locus_tag="VXE36_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0780233.1"
                     /translation="FSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVSKILRVKPN
                     GKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGR
                     KIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSL
                     NAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNT
                     NRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNL
                     NVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
BASE COUNT         1749 a          938 c          840 g         1511 t
ORIGIN      
        1 gcaaggtgaa gctgacgtgg tttgaagaga gtttcgaaga gtacaagtag gctgaaaaga
       61 atccagccac agcatggact attatatagc agattgaaat aagatgagaa caaatcgatt
      121 gggaaagtaa aattaatttc tataaatgtt ttagcaattg tttcgtacta ttttagattc
      181 agtctattat aacacattca gaaaagagaa aaaagtctgt tgattttgac catcataaaa
      241 agactggcaa tccagtctca aacatatatt atagaaattc tccactaaat actttcacga
      301 atattcagaa gcatgacaaa ggcaactaga agaaatagca ataaaacaaa gctaactgcc
      361 agagttccaa agctagtagc aatggttacc aaagctattg taaataagct aggtaaaaca
      421 accgtaatgg cactgataga agattgaact gctcccattg actcctcagg tatttgttta
      481 aaaacgagtt cttgcaatct aggagagaga acacctgcga aaaaggcatc caaggtacta
      541 aagatgagaa tccagtcaaa acgaactgtg gcaaatccta ctagaagaag caactggatg
      601 acaagtgagg catagagagc tgtttttatg gaaatggtat gttgcagata gccacttaca
      661 aggcttccga caatcagggc tgacagttca aaagtggata gcaaggcaag agattgacct
      721 gtttgtaaat tcaaaaaggg ttgattcctc aaaaatagag tagagacagg aaccgtaaca
      781 tttatcactg cttgactagt agagataata aacaaaacca agagcacctt attcatattc
      841 catatcaatt tcgatgattg gagcaaatgc tggcaaaagg attttacaga gagtccttct
      901 tgatagctaa tcgttttttc tactttcaag aggtcagttt ttatgaagag gatacctaaa
      961 aatgcgatta aaaaggtaag agcgttcagt aaggaaataa actggatgga tagaatgcct
     1021 agtaagactc ctcctaggat attactgatt gttttcacta aactaacagt tgactgttta
     1081 aatccaatag cttctgccag atggtcttgc ccaataattc taatgaaaat cggagtgagc
     1141 atggcgcctg aaaaagcact caatgtatca gacacgaggt taagcagaca aataaaggtt
     1201 actagcaaca aggaaaaaga ctgccctgaa agcgataggg acactataga gtaaagcaaa
     1261 aattttgtaa aactaatgac tgtgtatttc aagacacgat gatgttgaaa atctgccaaa
     1321 actcccagaa agatttgtaa aatttgggga agggtttctg aaatcgtaat gagtaaaatc
     1381 gccaaaggtg caaaagacgc atctgccaca taattcagaa aggccagata aaaaatcgta
     1441 tccccaagcg ttgaaatcca ctggttgata gttaattgcc taaaatctct attttgaaga
     1501 aatactttca tcacaactcc ttcttaagtt caaatgggaa tctttcccca gaaatagacc
     1561 gcgatactac taacaaccaa aattacagta acatcaaaag ctgaccaatg ccgttgtaga
     1621 ctatatgcag tccaataggc caataaatgg actttgtcat tctaaataag actgcaaata
     1681 taagacctcc acccatatag aagacaaagt ctgtcaagac ccaaccgtga ttactaatgt
     1741 gcgagacccc aaataaaaca gcggaaccaa gtacatctag cccccatttc tttccttttt
     1801 ccagagcagt catcactaat ccacgataaa tcatgtcttc aaaaatggga cctgcaatca
     1861 caggataaaa aaaatacatc aaaaatgccg tagctcctgt aaaagtagga gcagcatgtt
     1921 gataagaaat ttcatttcga gtaggtggga aaagaaaaaa ggtgacaaaa ttccaagcaa
     1981 caaaagcaag cagagctagg aaggaataga aaagatagga tcctttaaac tttctactat
     2041 tgattttctg ccatttcccc gaccaaatca tagcaataag agcaaataaa accacaagaa
     2101 aattcaacat catatccgac agataatagg caaagtcaga tagcccagca acaaggtcgc
     2161 tgcgtaaaac taaaacactg aacttctggt cagcaataac tagtagaaaa actataataa
     2221 agtagcggtg tgagattatc tttttcattc tattttctcc tatactatga aataaagaca
     2281 gtccctaccc aagaaaaagg caaggactct gaatatcaat aatggcgacg attaacagtg
     2341 gaagaatcat ggttaaaata tttcttccag aaattagtga ttgaccaaga cgttcctaaa
     2401 cctccccaag caccggctgg gataacagca ttattcccaa attcccctcc ataaactgtc
     2461 tccaactcag cttctgtcaa ttccattgtt tctgcaaatt gtaaatttaa catcttttac
     2521 actccttcaa ttatcttcat ttgtaaacca cttctgcgac ctaggatttg cttcaagtgc
     2581 tttacaagta cagtataaca cgaaaattgg cttattttaa aaaatcgcat atttgatatt
     2641 ttttcttata gaaatttctt atttgcgatt ttgatagatt tgattatttc cctggtataa
     2701 taaagttatt actaacaagg aggaatataa tagatgaaga aaagaaaaat ccaactgata
     2761 ctcctactta tttcggagtg ggttattgcc attccatttt taactaatct ataagttctt
     2821 tatattgctg aaaacgcaat tcaaaaaggg atgttaattg tggattttct aatacctgca
     2881 gagattggat aaagcgttca atctcttttt gattgcttcc ctttgtttga agaaagacac
     2941 tcatcttctt taaaaattgc cacgatactt tttcaaaaac atcatacggt cgtaacatcc
     3001 tctccaactc ggcttcgaag attgggatgt aggagaaaag ttttcgctcc atgagttctg
     3061 ataagatatt taagagtcct tgcttcatat acaatcgatt gtgtactaac tctttaaatt
     3121 ctttggattt ttcgagtaag gaggttgata aaaaaatcag atcttgattg ctcaagaagg
     3181 gcatggtatt gcaaaagaga tagagttcaa accaggtcca agactcgata gcatagagat
     3241 aggtggtcaa aaactcgcta tcctcctctg ctagtgggta gcttttattt agtgaatgga
     3301 tggcatcttt aatcacgatg gcattcaaac gacgataggt ctgcgccatc tgttcttgat
     3361 cgacttcctc caatagctgc tctaaagcag ctatatcctg atgggcaaag cgattcacaa
     3421 cctttcgacc gattcgcata tgtggagatt cttgatagtt gttgagcttg tgcccaaact
     3481 catcaaaggt cacatttata ccttggatag ctagaatcaa cttatccgca gacagcatgg
     3541 actgccctag ctcaaacttg gacaactgag aagctgttag cccgtcacaa gccacatctg
     3601 actgcttgag ctttctcgct aaacgtaatt ccttgtaaaa ttcccccaat tccatttttt
     3661 caatcatcct accacctcct agcttttgca tattatatca ttatttgtat tcatttgtca
     3721 aaatattctg atagttagaa aaaataaaaa agccagcctt aagctgactc taaaaggacc
     3781 gagccttgta caatacagaa ctcaatcctc gttctaaata gaatgtctaa cttttttggg
     3841 cagtacacga gcttggggaa cagccactgg aacgatgagg tgtgagctca aaatatcctc
     3901 cagttatgtt tttcctaata gtataccgga agagtgaaag gattttataa tggagcggtt
     3961 acaaagaacc tactttctat taaacagtat actatgaaaa tgtgaaaatt taacattttt
     4021 ttgtacaaat tttataaatt attgcctttt taatatcaat agttaatctc ttatccagat
     4081 cccccttgtg taaactttat ctttataagc ttcaaggccc ctatcccatc tatttgcaac
     4141 aattagatca ctttgttttg taaatagttc aaaattcttt tcaaaaatta cgttatctat
     4201 actaacgttt aaatttggtt catatactaa aatttttata ccgacaatca atagttcatt
     4261 aattatactt aaaatagctg actctttgta attatctgaa ttatatttca tccccaattt
     4321 atatattcct actatctttg gctttcgttc caatatttgt ttaactatga actgttttct
     4381 atttgtgttt gaaatatcaa tcgcttctat cactggggca tttatttcta taaattcttt
     4441 ttttaattgt ttagtatctt tgggaagaca atatcctcca aatccaaaag aaggattatt
     4501 ataaaaattt ccaattcttg gatctaaaca aacacctttt attacaactt cagcatttaa
     4561 acttctcctc tcagcaaaag aatctagttc attaaaaaaa gcaacacgga gagctaagaa
     4621 tgtgttagaa aaaagcttaa ttgcttctgc ttcagtagga gaaactaaca taacattttt
     4681 aatattggca gtactatgag tactaatcga aaggaacaac tctgcaattt ttcttccttc
     4741 aactgtctca tctccaacaa ctatgcgact tggatataaa ttatcatata tagaacaacc
     4801 ttctctcaaa aattcaggga caaaaatgat attttttgta tcaaacagcc tttttaattt
     4861 gtttgaaaag ccgatcggaa ctgttgactt taaaataatc tttccattag gttttaccct
     4921 cagaatcttc gataccgttt gttcgatttc atatgtatta aaactaccaa ttttctcatc
     4981 ataatctgtc ggaagcgcaa taatataata atcaatatta tttttaattt cagaaaat
//
LOCUS       DAVLHB010000080         4967 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLHB010000080 DAVLHB010000000
VERSION     DAVLHB010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.080"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            531..1679
                     /locus_tag="VXE36_002001"
     CDS             531..1679
                     /locus_tag="VXE36_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol--glycerophosphate
                     glycerophosphotransferase"
                     /protein_id="HEV0780234.1"
                     /translation="MVVLQNVKFLVRVVFMVIISIVLWPVRIKKNKILFINFNGKGYG
                     DNPKSICEYLRVTYPELDLVWLTKDNEDFPDGVRVVRYKSLQSFYEQASSKVWVYNVR
                     NFERLLKKRGQFYIQTWHGASSFKLIEKQADLPLKYILEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKKLSIDSDDYVILYAPTFRD
                     DGDASYLDINFERLLQSIEQEIKKKCKILIRLHPNDSHFSNNISFNHDIIDVTLFSDM
                     QELILLADVLLTDYSSAIFDFMLLNKPYVRYVNDLEKYAELRGVSDTYYELPDSIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     gene            1715..2743
                     /locus_tag="VXE36_002002"
     CDS             1715..2743
                     /locus_tag="VXE36_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0780235.1"
                     /translation="MKNNDLKIGSGAIHQISATLSQNNISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     gene            2759..3463
                     /locus_tag="VXE36_002003"
     CDS             2759..3463
                     /locus_tag="VXE36_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEV0780236.1"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     gene            3478..4311
                     /locus_tag="VXE36_002004"
     CDS             3478..4311
                     /locus_tag="VXE36_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEV0780237.1"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQGSIKPTYTFKNVKEMWKGI
                     V"
     gene            complement(4400..4792)
                     /locus_tag="VXE36_002005"
                     /pseudo
     CDS             complement(4400..4792)
                     /locus_tag="VXE36_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1672 a          655 c          950 g         1690 t
ORIGIN      
        1 actactattg acaaaacgat ggatttctat acttttacta ttttctttca ttatggaagc
       61 tacaattagc gattcaattt tttatagaaa ttttttattt atgggaatac cattttttgg
      121 aataggaatt cttattgcac agaagcaaaa gaagattatt aattgtaaaa taataaacaa
      181 aatattaatc ttgggaacaa ttatctatcc aatactaata tttttagaat attatatctt
      241 gggtaattct tttgagatct atataagttc tgtgctagca accataatat tgatgatttt
      301 cgcgattaaa tcacctaaag cgattaatat aaaaatactg aatgaaattg gagataaata
      361 tgcgactttt gtttacatta tacaccagtt tatcattgtg atatttaaat ttttagtatc
      421 taatgtttat attctcaaat ttgggacgat atttgtcttt ttgatatgtt gttttctagg
      481 ggttctattt caatttatca aaaacagact attaaaaagg tttagttaag atggttgttt
      541 tacaaaatgt taaattttta gtaagagttg tttttatggt tattatcagt atagtgttat
      601 ggcctgttcg gataaagaag aataagatac tatttattaa ttttaatggt aagggatatg
      661 gtgataatcc gaaaagtatt tgtgagtatc ttcgagttac atatccagag ttagatttag
      721 tttggcttac aaaagataat gaagattttc cagatggagt gagagttgta agatataaat
      781 ctctacaatc tttttatgag caagctagtt cgaaggtttg ggtttataat gtaagaaatt
      841 ttgaaagact actaaaaaaa cgcggacagt tttatattca aacttggcac ggtgcttcta
      901 gttttaaact gatagaaaag caggctgatt taccattaaa atatatttta gaagcaaagt
      961 atgatgcaag agtcacagat ataatgattt cagatagcag aaaacaaact gaagaatttc
     1021 aaaagtattt ttggtattca ggagaaattt ttgaggtggg gatgccgaga aatgatgcct
     1081 tgtttcacta taaggaagac tacgacaagt taaataatat cagaaaaaaa ctaagcattg
     1141 attcagatga ttatgttatt ttatatgccc ctactttcag agatgatggg gatgcatctt
     1201 atttagatat aaattttgaa cggcttttgc aaagtattga acaagaaatt aagaagaaat
     1261 gtaaaatttt aattagatta catcctaatg actctcattt tagtaataat atttctttta
     1321 atcatgacat aattgatgtt acgctattct cagatatgca ggaacttata ttattggcag
     1381 atgttttact gacagattat tcttccgcga tatttgattt tatgctttta aacaagcctt
     1441 atgtcagata tgtgaatgat ttagaaaaat atgctgagct taggggggta tcagatacat
     1501 attatgaatt gccggattct attattaaaa ctgctgaaga attgtatgac ttactgccta
     1561 aaaaaataga aaattttgat tatgattcta taaaaaaata tagaaatgaa atactgtgtc
     1621 caatctttaa tggaaccgct agtgaaaatg taggaaggag aataattcaa gagttgtgaa
     1681 gtaaaacatt gggttatttt taaggtaacg agatttgaaa aataatgatt taaagatagg
     1741 aagtggagct attcatcaaa tctccgctac actttctcaa aataatattt cgggaaagat
     1801 tttatattgt gctgatccag ttgtcgatga cttgtacggt tcgatagtac gttcacaaat
     1861 agaggaaatt ggtcgggtaa aggaagaaag ttgcaattat aatactattg cttatgcgat
     1921 gaatatagca gaaagggcta ttgccacaga tattgactgt attgtgggaa tgggaggagg
     1981 tcgtgtttta gatgtctgca agtatgcatc ttttatttcg aaacgtcctt acctatcgat
     2041 tccgacaaca gcagcaaatg atggcattgc ttccccagtt gctgttttga aaaggcagga
     2101 tgatagacca aaaagcttag gggcggctat cccctcaatg acactaattg atattgatgt
     2161 tattgcatca ggacctatac aaaatataaa agctggtatc ggtgatacaa tatccaatta
     2221 cactgcattg aaagattggg agttggcagt tgagcgaggg aaagatgaga tgcatggttt
     2281 tgcatatcta atgtcgcaaa attctttaga tgctttaatg aaaacgaagt ataattctat
     2341 tacccctgat tttattgaag ttttggtaaa ctctttagtt ttatcaggca ttgcaatgga
     2401 ttttgcggga agtagtagac ctgtcagtgg gtcagagcac ttatttagtc atgcattaga
     2461 ttactatggt tctacaagga atcttcatgg aattcaggtt gcattaggta cagtcgcagt
     2521 tttgaaatta attgaaaatt ctgttgatac tgtagtggat tacttgcaaa gatttgaggt
     2581 tcatattaac ccgaaacttt tggggataga tgaagagttg tttatttatt gtatgcaaca
     2641 tgctacaaaa atgagaagta atcgctatac ctatctgcat gaagttgatc ttagcacaga
     2701 tagattgaaa caaatatata aggaactcat aagcgagttg tagaaaagag aggaaaaaat
     2761 gaaagcactt attttagcag cagggttagg aacacgtcta gctccaatta ccaatgaggt
     2821 accaaaatct ttggtaccag tcaatggtaa gccaattttg atgaaacaaa ttgaaaattt
     2881 atatcaaaat aatattacag atattacgat tattgctgga tataagtcat ctgtattaac
     2941 agatgcagtt actgaaaagt atccagaaat taatattatt gataatgttg attttaaaac
     3001 gactaataat atgtattcag cctatctagg aaaagctgca atgggtgata gtgacttctt
     3061 aatgatgaat gcagatgtat tttatgatgc ttctgttatt aaaagtctgt tgcttcataa
     3121 agctccaaat gcaattgtaa ctgatttagg tatttatatt gaagagtcta tgaaagtcgt
     3181 agaaaaaaat ggtcgtttag tagaaatttc taaacagatt tcacctgagg aaactttagg
     3241 agcttctatt gatgtttata aattctctta tgaagcaggt gctcgattct ttgaaaagtg
     3301 taaggaattt attgaagata aacgagaact tcaaatgtgg agtgaggttg ctcttaatgc
     3361 aattctttct gaagttgaat ttgtagcatg tccattagag ggtcgttggt tagaaattga
     3421 taatcatgaa gacttagttg ctgcagaaaa actatttgct tgaaccgaat acggagaatg
     3481 aaattgacaa atagagttga ttattttggt gctgatatta gtgaacttca gaataaaaaa
     3541 ttattcttat ttgatatgga tggtaccatt tatgaagaag ataggttgtt tgagggtact
     3601 ctcgaattat tagactatat tcataatatt ggcggtgagt atatttttat tacaaacaat
     3661 tcatctaagt ctgttgttga ctatgttgaa aaagttaaca gattaggtat taaagctgaa
     3721 cgagataatt tttttacctc tgctcaagcc acaattgttt atattaaaga aaattatcct
     3781 aaatctaaag tttattgcca aggaacaaaa tctttgataa aagaactatc tgacgcagga
     3841 attgatgtaa ctgagcaagt tagtgctgat atagatgttg ttcttgttgg ttttgataca
     3901 gaattaacca gtgataaaat tcgtaatacc tgcgagattc tatcaacaaa ggacgtacct
     3961 ttcatagcta ctaaccctga tattcgctgc ccagtatcgt ttggattcat cccagattgt
     4021 ggttctattt gtgatatgat tagtaaatca gtcgatagga aacctgttta cataggtaaa
     4081 cctgaaccta cgatggttga tattgttcga aaaaaattaa attattctct atttgaaaca
     4141 gttgtgattg gagatcgctt gtatacggat atcatgactg gtataaatgc aggagtaact
     4201 tcagtttgtg tgctgacagg agaagcaacg gtgaatgata ttcaacaagg tagtataaaa
     4261 ccgacttata catttaaaaa cgtgaaagaa atgtggaaag gaattgtctg attttttcat
     4321 tctgaatagt gaattcatga atactgtcaa aatactcgta tgtatttaaa ttgattttat
     4381 tattagactt cctgcaaaac tagaatccta gttcatgatt gataatagca gcaatcaaat
     4441 tcattcgtaa tccgaagcgt ttacgatgat ttcgataggt tgttgaaaac attttaaacg
     4501 tttttacttt ggcaaagatg ttctcaacct tgcttctctc cttggatagc gcatggttac
     4561 aggctttatc ttcaactgtt agcggtttga gtttgctgga tttacgtgga gtttgtgctt
     4621 gaggatatat cttcatgagc ccttgataac cactgtcagc caagatttta ccagcttgtc
     4681 cgatatttct gcgactcatt ttgaacaact ttatatcatg acaatagttc acagcgatat
     4741 ccaaagaaac aattctccct tgacttgtga caatcgcttg agccttcata gcgagaaata
     4801 tctatcctat cttctagaat gtcttccaaa cgaggaaact ctcgtaaaca aagaggtttt
     4861 agaggcctat ttaccgtgga ctaaagttgt acaagaaaag tgcaaataag aaatctccag
     4921 attaggaact atccgtgagt tctctagtct ggagattttt caatata
//
LOCUS       DAVLHB010000081         4887 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLHB010000081 DAVLHB010000000
VERSION     DAVLHB010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.081"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..832
                     /locus_tag="VXE36_002006"
     CDS             <1..832
                     /locus_tag="VXE36_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0780238.1"
                     /translation="IVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFK
                     LVVKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSET
                     AYHFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGM
                     GTRLELRSVDPMANPYIAMAVLLEVGLYGIESKIEAPAPIEENIYIMTAEERKEAGIT
                     DLPSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY
                     "
     gene            complement(928..1047)
                     /locus_tag="VXE36_002007"
     CDS             complement(928..1047)
                     /locus_tag="VXE36_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0780239.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            1592..2911
                     /locus_tag="VXE36_002008"
     CDS             1592..2911
                     /locus_tag="VXE36_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0780240.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYI
                     QRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNS
                     TGLGTLGRLAIYHENKNPYAWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEE
                     KASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            2968..3765
                     /gene="psrA"
                     /locus_tag="VXE36_002009"
     CDS             2968..3765
                     /gene="psrA"
                     /locus_tag="VXE36_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0780241.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            3776..4375
                     /locus_tag="VXE36_002010"
     CDS             3776..4375
                     /locus_tag="VXE36_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0780242.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVATSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQL"
     gene            complement(4329..>4887)
                     /locus_tag="VXE36_002011"
     CDS             complement(4329..>4887)
                     /locus_tag="VXE36_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0780243.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIIFKVDLLFQKVSQLFE"
BASE COUNT         1663 a          757 c          879 g         1588 t
ORIGIN      
        1 gattgtgaat gtcttgacca aaatgggatt tgaagtagaa gcgagtcacc acgaggttgc
       61 ggttggacag catgagattg actttaagta cgatgaagtt ctccgtgctt gtgataagat
      121 tcaaatcttt aagcttgttg ttaaaaccat tgctcgcaaa cacggacttt acgcaacatt
      181 tatggcgaag ccaaaatttg gtattgctgg atcaggtatg cactgtaata tgtccttgtt
      241 tgatgcagaa ggaaataacg ccttctttga tccaaatgat ccaaaaggaa tgcagttgtc
      301 agaaacagct taccatttcc taggcggttt gatcaagcat gcttacaact atactgccat
      361 catgaaccca acagttaact catacaaacg tttggttcca ggttatgaag cgcctgttta
      421 cattgcttgg gctggtcgta accgttcgcc acttgtgcgc gtacctgctt cacgtggtat
      481 gggaactcgt cttgagttgc gttcagtgga tccaatggcg aacccttaca ttgctatggc
      541 tgttcttttg gaagttggtt tgtatggtat tgaaagtaaa atcgaagcac cagctcctat
      601 cgaagaaaat atctacatca tgacagcaga agagcgcaag gaagctggta ttacagacct
      661 tccatcaact cttcacaacg ctttgaaagc tttgacagaa gatgaagtgg ttaaagctgc
      721 tctcggagat cacatctaca ctagcttcct tgaagccaaa cgaatcgaat gggcaagtta
      781 tgcaaccttc gtttcacaat gggaaattga taattattta gacctttact aatactaata
      841 tagaagaaag attgcctgtg ggtaaacagt cacacagcag tctaagccat caaataccta
      901 taacccttaa aatagcgatt tcggtcgcta tttatttttc gaaaaatcct cttgactctt
      961 ttgcgaatta gatttatcat cagacgtgta gaagaaaatt aaggagtcac tatggaaaaa
     1021 ttcaatttca aaaacaatat cgggcaagaa aacaagttac ttcaaatcga aatctacaag
     1081 tttactaact tttgcaagct tcaaaattac acatctgtaa atattttttc gaaagatata
     1141 tttgaaacca tagtaaattg agactagaat agtacactac atctgctaaa aatttctaga
     1201 aactaattta actttcctaa tcgatttgtt tacatcttat ttcaatctac tatattatct
     1261 caataaatga tgatggcgac tgttttgttt gtgcttgtcg atttttgaat cctgatcgag
     1321 cggaagaata tttctgccga ggttgccaag gggaaaatac tgaagatatt gaattttatg
     1381 atgaacaatt acaggcagaa aaggtggagg ttttgaatat tcgattggaa gtaaaaaatt
     1441 gaattatcta caatctcatc aacaataaac ctatttcaac cccattatct ataggcgtat
     1501 ttttacgcct ttttatatac ttgaagcaca taagaaacat tatgggaagt ttgctgatgg
     1561 aagtactcaa gaaattgatg ttccttatga tattcctgat acttgggagt gggtgaggtt
     1621 ttctacattg gttgaaattg tcagaggtgg ctctccacga ccaatcaaag attatcttac
     1681 ttctgaagta gatggaataa attggataaa aataggtgat actgaaaagg gtgaaaagta
     1741 tataaataat gttaaagaaa aaatcaaaaa atcagggctt aacaaaacta gatttgtaaa
     1801 aaaaggtaca tttttgttaa ctaattctat gagttttggt agaccttata ttttgaatgt
     1861 tgatggtgca atacacgatg gatggttggc tatttcgaac tatgaaaact cattaaataa
     1921 agattaccta ttctatattc tttcatcaaa tgtagtttat tctcaatttc tatctctaat
     1981 tagtggagct gttgtgaaaa acttgaatag tgataaagtt gcttctattc ttatccctct
     2041 ccccccacta tccgaacaac aacgcataat agaagcaatc gaatcagctt tagaaaaagt
     2101 agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat ttccagataa
     2161 actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac aagacccaaa
     2221 tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa aactctttga
     2281 agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag gagatgataa
     2341 ctcttattat gaggaagtac cttgtgaaat accagaaagt tgggaatggg tgaggttaaa
     2401 cgatataacc tcctacattc aaagagggaa gtctccaaaa tattcaaata ttcctatata
     2461 ccctgtgatt gctcagaaat gtaatcaatg gtctggcttt tctattgact tagcaagatt
     2521 tattgatccc gaaacagttc atagttacca gaaagaaaga ttactaaggg atggtgattt
     2581 aatgtggaat tcaacaggtc taggtacgtt aggacgatta gctatttacc atgaaaataa
     2641 aaatccttat gcctgggctg ttgcagatag ccatgttaca gttataagag tcttatcggg
     2701 ggttattaat tgccatttca tctataattt tctttcctct cctattgttc agtcagttat
     2761 tgaagaaaaa gcgtcgggta gtacaaaaca aaaagaatta ttaacgaaaa ctataaaaga
     2821 atatttaatc cccctcccac cccttcctga acaatccaga atcgttgata aaatcgaaca
     2881 atttttcgcc catattgacg cactaattta gtataatagt tttacgtgcg gtggaatttc
     2941 tatcaaacat aagataggag ttttacgttg aaagattttg aattacattt gaagaaagct
     3001 ggtttagctg aaaatactgt gcgttcgtac ctttatggtg ttcgattttt cttggagaat
     3061 tacgaactca aaatggaaga tttatttgaa tacaaaggat atttattaga caattttaaa
     3121 cctaaaactg tcaatttgcg actacaagga gtaaataaat atctggcttt tattggtcat
     3181 gatgatttga aattaaaatt tgtcaaagta cagcaaaaac cgtttttaga agatgtcatt
     3241 agccatgctg attacctttt tcttaaacgt agtttgaaaa aagatggtat tttaaaatgg
     3301 cattttgtcg tttggttttt aggtgcaact ggggctcgtg taagtgaact tattaaacta
     3361 aaagtagagc atgtagaaat cggttatttt gacatttact caaaaggtgg taaaattcgt
     3421 agactgtaca ttcctaaaaa attaagaaat agttgtctta gttggttaga atcagaaaat
     3481 cgccgaagtg gttatttatt tttgaataaa tttaacgaac caattacagc aagaggagtt
     3541 gctcaacagt taaaaaatta tgctgataaa tacaaaatga atcctaaagt aatttaccct
     3601 cattctttta ggcatttatt tgctaagaat tttttagcga agtataatga tattgccttg
     3661 cttgcagatt tgatgggaca cgaaagtata gaaactactc gaatttatct aaggaaaaca
     3721 gctactgaac aacaaaatat tgtagataaa attgttaatt ggtaaaaaat aacaggtggt
     3781 caaactgact acctgctatt tttgtgatta tggctcttat tatgggaata tacctatgaa
     3841 ttgggttgtt ataaaaataa aagatatttt ttcaatgaat acaggtcttt cttacaagaa
     3901 gggcgattta agcattaata ataaaggtgt tagaattata cgtggtggta atattaagcc
     3961 tttagaattt tctctgttgg ataatgatta ctacattgat acacaattca tctcctctga
     4021 gcaagtttat ttaaaacata atcagctaat aacacctgta gcaacctctt tagaacatat
     4081 tggaaagttt gcaagaatcg ataaagacta tgatggtgtt gtggctggtg gatttatttt
     4141 ccaattaaca ccattcgaaa gttcagagat tatttcaaaa tttctattat ttaacttgtc
     4201 ctctccgtta ttttataaac aattgaaagc aataactaaa ctatcaggtc aagctttata
     4261 taatattcct aaaactacac tgagcgagct attaattccg ttagctcctt ttgaggaaca
     4321 ggaacttatt actcaaaaag ttgagaaact ttttgaaaaa gtaaatcaac tttgaaaatg
     4381 attcttttca tctcttcatg attagaaata gggattaata attcggagat actggtacta
     4441 tttaatgttt tccctttgat agcatctttt gaatcaccta aagtagagat aagtggcaaa
     4501 aatatcatta agtaatctct gataatattt tctttattag cataggggaa tatcgatata
     4561 atggcttcat tatgagtggc aggaatatcc aatatggcaa cttttccaat agataattta
     4621 aaactcatta ataaagttcc tttaggtgaa atgtctattt tctttgattt taatgctaat
     4681 ttagaaatag attctctcgt attagttaca taaccagata taggcatatc tgatatagat
     4741 acccaaggta tttcagttcc ccaaaaagta gcttcactgc gtggaggagt ttttcctatt
     4801 ctgaagttaa ctaggctagc aaatttaata tatctccatg cttctgggat ttcatatata
     4861 ggataagagg ttgtttcgtc tttgttc
//
LOCUS       DAVLHB010000082         4837 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLHB010000082 DAVLHB010000000
VERSION     DAVLHB010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.082"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            256..1635
                     /locus_tag="VXE36_002012"
     CDS             256..1635
                     /locus_tag="VXE36_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0780244.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            1649..2314
                     /locus_tag="VXE36_002013"
     CDS             1649..2314
                     /locus_tag="VXE36_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0780245.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            2449..2607
                     /locus_tag="VXE36_002014"
     CDS             2449..2607
                     /locus_tag="VXE36_002014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780246.1"
                     /translation="MKIKDQTRKLATGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            2669..3208
                     /locus_tag="VXE36_002015"
     CDS             2669..3208
                     /locus_tag="VXE36_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0780247.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            3275..3685
                     /locus_tag="VXE36_002016"
     CDS             3275..3685
                     /locus_tag="VXE36_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0780248.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            3801..>4837
                     /gene="pavB"
                     /locus_tag="VXE36_002017"
     CDS             3801..>4837
                     /gene="pavB"
                     /locus_tag="VXE36_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0780249.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDG"
BASE COUNT         1363 a          915 c         1093 g         1466 t
ORIGIN      
        1 cctgtgacta gctttctaat cgatgccttg gttctcattg cctataatca aaaagagaaa
       61 ttttctcctg aaaagcatat agagtagctg gcgttaaaag ctcctgtctt gcttttttga
      121 cctatagtca tatctatcaa gtattgttct tgcctaagct atcaataaaa aggtggcatt
      181 ttttaggctt ggtgttagtg aattttgcct tatcctatct aagtcatttc gagcttttta
      241 tggtacaatg gaaacatgtt attcaaatta tctaaggaaa aaatagagct aggcttatct
      301 cgtttatcgc cagcccgtcg tatttttttg agttttgcct tggtcatttt actaggctct
      361 cttcttttga gcttgccctt tgtccaagtt gaaagctcac gagcgactta ttttgatcat
      421 cttttcactg ctgtctctgc agtctgtgtg acaggtctct caacccttcc agtagctcac
      481 acctataata tctggggcca aataatctgt ttgctcttga ttcagatcgg tggtctaggg
      541 ctcatgacct ttattggggt tttctatatc cagagcaagc aaaagcttag tcttcgtagc
      601 cgtgcaacta ttcaggatag ttttagttat ggagaaactc gatctttgag aaagtttgtc
      661 tattctattt ttctcacgac ctttttggtt gagagcttgg gagctatttt gcttagtttt
      721 cgccttattc ctcaacttgg ctggggacgt ggtcttttta gttccatttt tctagcgatc
      781 tcagccttct gtaatgccgg ttttgataat ttagggagca ccagtttatt tgcttttcag
      841 accgatttac tggtcaatct ggtgattgca ggcttgatta ttacaggcgg ccttggtttt
      901 atggtctggt ttgatttggc tggtcatgta ggaagaaaga aaaaaggacg tctgcacttt
      961 catacgaagc ttgtattatt attgactata ggtttgttgt tatttggaac ggcaactact
     1021 ctctttcttg agtggaacaa tgctggaacg attggcaatc tccctgttgc cgataaggtt
     1081 ttagttagct tttttcaaac agtgacgatg cgaacagctg gcttttctac gatagattat
     1141 actcaggctc atcctgtgac tcttttgatt tatatcttac agatgtttct aggtggggca
     1201 cctggaggaa cagctggggg actcaagatt acgacatttt ttgtcctctt ggtctttgca
     1261 cgaagtgagc ttctaggctt gcctcatgcc aatgttgcga gacgaacgat cgcgccgcga
     1321 acggttcaaa aatcctttag tgtctttatt atctttttga tgagcttctt gataggattg
     1381 attctgctag ggataacagc caaaggcaat cctcccttta tccacctcgt atttgaaacc
     1441 atttcagctc ttagtacagt tggtgtaacg gcaaatctga ctcctgacct tgggaaattg
     1501 gctctcagtg ttatcatgcc acttatgttt atgggacgaa ttggtccctt gaccttgttt
     1561 gttagcttgg cagattacca tccagaaaag aaagatatga ttcactatat gaaagcagat
     1621 attagtattg gttaagaaag gaaagagcat gtcagatcgt acgattggaa ttttgggctt
     1681 gggaattttt gggagcagtg tcctagctgc cctagccaag caggatatga atattatcgc
     1741 tattgatgac cacgcagagc gcatcaatca gtttgagcca gttttggcgc gtggagtgat
     1801 tggtgacatc acagatgaag aattattgag atcagcaggg attgatacct gcgataccgt
     1861 tgtagtcgcg acaggtgaaa atctggagtc gagtgtgctt gcggttatgc actgtaagag
     1921 tttgggggta ccgactgtta ttgctaaggt caaaagtcag accgctaaga aagtgctaga
     1981 aaagattgga gctgactcgg ttatctcgcc agagtatgaa atggggcagt ctctagcaca
     2041 gaccattctt ttccataata gtgttgatgt ctttcagttg gataaaaatg tgtctatcgt
     2101 ggagatgaaa attcctcagt cttgggcagg tcaaagtctg agtaaattag acctccgtgg
     2161 caaatacaat ctgaatattt tgggtttccg agagcaggaa aattccccat tggatgttga
     2221 atttggacca gatgacctct tgaaagcaga tacctatatt ttggcagtca tcaacaacca
     2281 gtatttggat accctagtag cattgaattc gtaaagaggg atgacccctc ttttttgatg
     2341 cctaagatgg caaatagaga cagaagcccc ttgtcttcta gtaaaagttc ttcaaaggct
     2401 ggactttatg gtaaaataga aagaagtgac aagagagagt aatactcaat gaaaatcaaa
     2461 gatcaaacta ggaaactagc tacgggctgc tcaaaacact gttttgaggt tgtggataga
     2521 actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     2581 aacatctata cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa gagtataaga
     2641 aaaaatcagt cccctaaagg agtagattat gaagttattg tctatcgcaa tttctagcta
     2701 taatgcagca gcctatcttc attactgtgt ggagtcgcta gtgattggtg gtgagcaagt
     2761 tgggattttg attatcaatg acgggtctca ggatcagact caggaaatcg ctgagtgttt
     2821 agctagcaag tatcctaata tcgttagagc catctatcag gaaaataaat gccatggcgg
     2881 tgcggtcaat cgtggcttgg cagaggcttc tgggcgctat tttaaagtag ttgacagtga
     2941 tgactgggtg gatcctcgtg cctacttgaa aattcttgaa accttgcagg aacttgagag
     3001 caaaggtcaa gaggtggatg tctttgtgac caattttgtc tatgaaaagg aagggcagtc
     3061 tcgtaagaag agtatgagtt acgattcagt cttgcctgtt cggcagattt ttggctggga
     3121 ccaggtcgga aatttctcca aaggccagta taccatgatg cactcgctga tttatcggac
     3181 agatttgttg cgtgctagcc agttctaact gcctgaacat actttttatg tcgataatct
     3241 ctttgtcttt acgccccttc agcaggtcaa gaccatgtac tatctgcctg tcgatttcta
     3301 tcgttatttg attgggcgtg aggaccagtc tgtcaatgag caagtgatga ttaagtgcat
     3361 tgaccagcaa ctcaaggtca atcgactctt ggtagaccaa cttgatttgt cccaagtgag
     3421 tcatcccaaa atgcgagaat atctgctgaa tcatattgaa atcacgacgg tgatttccag
     3481 taccctgctc aaccgatctg gaacagcgga gcatctggca aaaaaacgcc aattgtggac
     3541 ctatattcag cagaaaaatc cagaagtctt tcaggctatt cgtaagacca tgttgagccg
     3601 tttgaccaaa cattctgtct tgccagatcg caaactgtcc aatgtcgtct atcaaatcac
     3661 caaatctgtt tatggattta attaatataa gtgttttata agagggattt aagaaaaatt
     3721 ttaacttttt cttagtcctt tttaatttca ggagattata ctagagtcat caaataaaga
     3781 aagactctaa ggagaatcct atgaaattca atccaaatca aagatatact cgttggtcta
     3841 ttcgccgtct cagtgtcggt gttgcctcag ttgttgtggc tagtggcttc tttgtcctag
     3901 ttggtcagcc aagttctgta cgtgccgatg tggtcaatcc gaccccaggt caagtcttac
     3961 ctgaagagac atcgggaacg aaagagggtg acttatcaga aaaaccagga gacaccgttc
     4021 tcactcaagc gaaacctgag ggcgttactg gaaatacgaa ttcacttccg acacctacag
     4081 aaagaactga agtgagcgag gaaacaaact cttctagtct ggatacactt tttgaaaaag
     4141 atgaagaagc tcaaaaaaat ccagagctaa cagatgtctt aaaagaaact gtagatacag
     4201 ctgatgtgga tgggacacaa gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg
     4261 gagtgaaaga aaatacaaaa gacagcatcg atgttcctgc tgcttatctt gaaaaagctg
     4321 aagggaaagg tcctttcact gccggtgtaa accaagtaat tccttatgaa ctattcgctg
     4381 gtgatggtat gttaactcgt ctattactaa aagcttcgga taatgctcct tggtctgaca
     4441 atgggactgc taaaaatcct gctttacctc ctcttgaagg attaacaaaa gggaaatact
     4501 tctatgaagt agacttaaat ggcaatactg ttggtaaaca aggtcaagct ttaattgatc
     4561 aacttcgcgc taatggtact caaacttata aagctactgt taaagtttac ggaaataaag
     4621 acggtaaagc tgacttgact aatctagttg ctactaaaaa tgtagacatc aacatcaatg
     4681 gattagttgc taaagaaact gtcgaaaaag ctgttaaaga taacgttaaa gacagtatcg
     4741 atgttccagc agcctaccta gaaaaagcca agggtgaagg tccattcaca gcaggtgtca
     4801 accatgtgat tccatacgaa ctcttcgcag gtgatgg
//
LOCUS       DAVLHB010000083         4725 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLHB010000083 DAVLHB010000000
VERSION     DAVLHB010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.083"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..372
                     /locus_tag="VXE36_002018"
     CDS             <1..372
                     /locus_tag="VXE36_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV0780250.1"
                     /translation="DILQLLSDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTY
                     ELKMQDATISSSELEFLCDLLLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIIS
                     ALQNTIPFESIKERIRPHYGS"
     gene            362..682
                     /locus_tag="VXE36_002019"
     CDS             362..682
                     /locus_tag="VXE36_002019"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV0780251.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            745..2520
                     /locus_tag="VXE36_002020"
     CDS             745..2520
                     /locus_tag="VXE36_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV0780252.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            2521..3906
                     /locus_tag="VXE36_002021"
     CDS             2521..3906
                     /locus_tag="VXE36_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV0780253.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            3929..4540
                     /locus_tag="VXE36_002022"
     CDS             3929..4540
                     /locus_tag="VXE36_002022"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV0780254.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         1555 a          679 c          998 g         1493 t
ORIGIN      
        1 gatattttac aattactttc agatgaagga agtatttctg ctaaagaatt tatatacatt
       61 gtagaaaatc aagaaatatt tgtgtggttc aataaaataa atccaagctt agattcaatc
      121 ttttcaactt atgaattgaa gatgcaggac gcaacaattt catcttctga gttagaattt
      181 ttatgtgatt tactattgta taaaacttta gatcaaggaa ggtacaatgt agaggggccg
      241 ttagttcttg ctagatattt attgggatgt gagtttgaag taaagaatct cagaatgatc
      301 atatcagctc ttcaaaatac aattcccttt gaatcaataa aagaaaggat acgcccacat
      361 tatggaagct aataagtata aaattggcat aattggtagc cgtgatatta ttttaccatt
      421 tagcatgatt gggtttgata tatttcctgc ctaccaagaa caagaagcta taaatacact
      481 aagaaaatta gctcaatctg attatggtgt catttatatc actgaagaca ttgcttcaat
      541 gatattagat acaattcgcc attatgattc ccaagttgtg cctgctatta ttttattacc
      601 gactcataaa caaggtttaa atttaggatt aaaacgtata gaggataatg tagagaaagc
      661 agtaggacac aatattttat aataatgtac aaaattgtct gtaatattat tctataattt
      721 ttggacttag taaggagaat aactttgact caagggaaga ttataaaagt atcgggacct
      781 ctagttattg catcaggtat gcaggaggct aatattcaag atatttgccg tgtaggtaag
      841 ctagggttaa tcggtgaaat tattgaaatg agaagagatc aggcatctat ccaagtctat
      901 gaagaaacat ctggtcttgg tccgggagaa cctgttgtta caactggaga acctctctcg
      961 gttgaattag ggccaggatt gatttctcaa atgtttgatg gcatacaacg cccattagat
     1021 cgatttaaat tggctactca taatgatttt ctagttcgtg gggtagaagt tccaagtttg
     1081 gatagagata ttaagtggca ttttgattcc actatagcaa ttggtcaaaa agtgagtacg
     1141 ggtgatattc ttggaactgt caaggaaacc gaggtagtta atcataaaat tatggttcct
     1201 tatggagtat ctggagaagt cgtttctatt gcatctggcg attttacaat tgatgaagtt
     1261 gtatatgaaa taaaaaaatt ggacggtagt ttctataaag gaacgcttat gcaaaaatgg
     1321 cctgtccgca aggcgcgtcc tgtttctaaa cgtttaattc cagaagaacc attaatcaca
     1381 ggtcaacgag ttattgatgc attctttcca gtaaccaaag ggggagctgc agcagttcct
     1441 ggaccgtttg gagcaggaaa gacagttgta caacaccaag tagctaaatt tgccaatgtt
     1501 gatattgtta tttatgtcgg ttgtggagaa cgtggaaatg aaatgacgga tgtactgaat
     1561 gagtttcctg agttgattga ccctaatacc ggacaatcaa ttatgcaacg gacagttctg
     1621 attgctaata cttcaaatat gcctgttgct gctcgtgagg cttcaattta tacaggaatt
     1681 accatggctg agtattttcg tgatatgggc tactctgtcg ccattatggc tgattcaact
     1741 tcacgttggg cagaagcgct acgtgaaatg tcaggacgtc tagaagaaat gcctggtgat
     1801 gagggttatc ctgcttatct gggaagtcgt atcgctgaat attatgaaag agcaggacgt
     1861 tctcaggttc tagggcttcc agaacgtgaa ggaacgatta ctgctattgg agctgtatcg
     1921 ccacctggtg gagatatttc agaaccagtt actcaaaaca ctttacggat tgtgaaagtt
     1981 ttttgggggc ttgatgctcc gttggcacag cgacgtcatt ttcctgcaat taactggctt
     2041 acatcttatt cactatataa agacagtgtg ggcacttata tagatggtaa agagaagaca
     2101 gattggaata gtaaaataac tcgtgcgatg aactacttac aacgggaatc tagtttagag
     2161 gaaattgttc gtcttgttgg aattgattct ctgtctgata atgaacgact aacgatggaa
     2221 attgctaaac aaattcgaga agattatttg caacagaacg cttttgattc ggtagataca
     2281 ttcacttcgt ttgcaaaaca agaagcaatg ctaagtaata ttctcacttt tgctgatcag
     2341 gcaaatcatg ctttagagtt gggttcttac tttacagaga ttatggaagg taccgtggca
     2401 gttcgagacc gtatggcgag aagtaaatat gtttcagaag atagattaga tgaaatcaaa
     2461 attatatcaa atgagattac acatcaaatt catttgatat tagaaacagg aggtctataa
     2521 atgagtgtta taaaagaata cagaactgct agtgaagttg ttgggcctct tatgattgtt
     2581 gaacaagtaa ataatgtgtc ttacaatgag ttagttgaaa ttcaacttca taatggagaa
     2641 attcgtcgtg gacaagtttt agagatccac gaagataaag caatggttca gctttttgaa
     2701 ggatctagtg gaataaattt agaaaagtct aaaattcgtt ttgctggtca tgcattagaa
     2761 ttggctgtat ctgaggatat ggttggtcgt atttttaatg ggatgggaaa accaattgat
     2821 ggtggaccag atttaattcc agagaaatat ttagatattg atggtcaagc tattaatcct
     2881 gtatctagag attatccaga tgaatttatt cagacaggga tctcctctat tgatcatttg
     2941 aatactcttg tacgtggtca aaaattacca gtattttcag gttcgggctt acctcataat
     3001 gaattagctg ctcagatagc aagacaagcg actgttttaa attctgatga aaattttgcg
     3061 gttgtatttg cagcaatggg tattactttt gaagaagctg agttttttat ggaagaactc
     3121 agaaaaacag gagcgatcga tcgttcggtt ttatttatga acttggcaaa tgatcctgca
     3181 attgagcgta ttgcaactcc ccgcattgct ttaactgcgg cagagtatct agcttttgaa
     3241 aaagatatgc acgttctagt tatcatgacg gatatgacta actattgtga agcgttacgt
     3301 gaagtctcgg cagctcgccg tgaagttcca gggagacgag gctatccggg atatttatat
     3361 acaaatttat caactctata cgaaagggct ggtcgcttag ttggtaaaaa aggttcggtg
     3421 acacagattc ctattttaac aatgccagaa gatgacataa cacatccaat tcctgattta
     3481 actggataca ttactgaagg gcaaattatt ttgtcgcatg agttgtataa tcaaggttat
     3541 cgtccaccaa tcaatgtttt accttctctc tctcgattaa aagataaggg atctggagaa
     3601 ggtaaaactc gtggagatca tgctccaact atgaatcaac tgtttgcagc ctatgcccaa
     3661 gggaaaaagg ttgaagagtt agcagtagta ttaggagaat cggctttatc tgatgtagat
     3721 aaattgtatg tgaggtttac aaagcgtttt gaagaagagt acataaacca aggattttat
     3781 aaaaatcgaa atatagaaga tacgttgaat cttgggtggg aattactatc aattcttcct
     3841 agaacagagt taaaacgtat caaagatgat ttgcttgata aatacttacc tttggtagaa
     3901 gtttaatccg gaaatggagt gattatctat ggtacgtttg aatgtaaaac caactcgtat
     3961 ggaattgaat aacttaaagg aacgtttgac aacagctgaa cgtggacata agttattaaa
     4021 ggataaaaga gatgaattga tgaggcgatt tatttctttg attcgtgaga ataatcaact
     4081 tcggaaagaa gtggaaagtt atctaattga taatctaaaa tcctttgcag ttgctaaatc
     4141 attaaagaat tctcaaatgg tggaggaatt attttcaatt ccatcgaaag aaattgaatt
     4201 atttgttgag aaagaaaata tcatgagtgt aacagttcct agaatgcata tgaatattac
     4261 ttctcaaaat gagaacagtg aatacagcta tttatcttct aatagtgaaa tggatgatgt
     4321 atttgctaca atgaatagtt taatttataa attactaaga ctggcagaag ttgaaaaaac
     4381 gtgtcagtta atggctgatg aaatagaaaa aacacgtaga cgtgtaaatg gtttagaata
     4441 ctcgattatt ccaaacttgt cggaaactat tcattatata gaattgaaac tagaggaggc
     4501 agaaagagcc aatttagttc gtattatgaa agtgaagtag atcctttatt tagattatta
     4561 attagatgaa caaatatcag cttggataag gctttaagcc tttctaagct ttttttattg
     4621 acagtatcag gatatctttt tcaaaatttt ggtttgttag ataatgaaaa tgtttctact
     4681 aatctagatt taggattagt aaatcgtaaa tgtaattata tagaa
//
LOCUS       DAVLHB010000084         4638 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLHB010000084 DAVLHB010000000
VERSION     DAVLHB010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.084"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            89..2698
                     /locus_tag="VXE36_002023"
     CDS             89..2698
                     /locus_tag="VXE36_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0780255.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSERLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGGIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            2731..>4638
                     /locus_tag="VXE36_002024"
     CDS             2731..>4638
                     /locus_tag="VXE36_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEV0780256.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNY"
BASE COUNT         1622 a          579 c          927 g         1510 t
ORIGIN      
        1 gaatccaaag gattctccct ttttatttaa ataagtctgt ctagctatag atatattaag
       61 tttgataaaa tttcttggag attttgttat ggattataat ttcaatttgg agcatccttt
      121 ctttttcact aataatgatt atagtacaga tactagcata aagtaccaag taagtctgcc
      181 ttttaattgg cacgaagtaa tgaataatga tgagtgggtt tatcaatacc ctattggaaa
      241 atttgttgaa agacaagggt ggaaaataca cattagttca gagtataaca gttcacatga
      301 attgttacaa gatgtagcaa aaatttgcca tgaaatgcga attccattta aacatcttag
      361 tacagaagac aaatttatca tgcgaaacgg gaaattggtt agtcgaggat tttctggtaa
      421 atttattaca tgttatccaa atcaaaatga attagagtcg gttttgcaaa ggttagaaag
      481 tgctttaaag caatataatg ggccatatat tttaagcgat aaacgttggg atgaagcacc
      541 aatatatctg aggtatggtg tgtttaggcc gtcaagggat gatgaaaaga aggttgctat
      601 tgatgaatta attgttggcg atgaagttgt taaagatgaa cgtttaccag tatttaaaat
      661 tccaaaaggt atagtgcccc ctgacttttt gaataaatgg cttgacaaga aagataaaaa
      721 acagggagac tttcccttta ttatagataa tgcaattaga ttttcaaaca gtggtgggat
      781 atataatgct aggctaaaag aagatgggaa aaaaataatt ttaaaagagg ctagaccgta
      841 tacaggtcta ggatttgatg gtacttattc ttcagagaga ttagcttcgg agtgcaaagc
      901 actaaaaatt ctaaatgaat ggagtgagac gcctaaaata tactggcacg gtaagatctg
      961 ggagcacacc ttcttaggaa ttgaacatat gaagggcgtt ccactaaata gatgggttac
     1021 caataatttt cctttatatg aagttgttga taagaccaaa gattatctat tgagagtttc
     1081 aaagatagta gaaaaactca tcgatttaac gaataagttt cattctgaaa atgtatatca
     1141 tcaagattta catttaggaa atatcttggt taaggatgaa gatgagatta gtataataga
     1201 ctgggaacag gctgtctttt caaatgatga aaaagttgta cataaagttg cagcccctgg
     1261 ttttagagca tggcgagaaa cacttcccag tgagatagat tggtatggta ttagacaaat
     1321 agctcattat ttatacatgc cactagtaac tacatcggat ttgacataca actatgtaag
     1381 tcaaaccagg atagaaggaa aaaaactatt tgagtctttg ggttatacaa gagaacatat
     1441 agattatgta gaaagtttat tgtcatatct agattctaaa tgtccacaga ttgagaatat
     1501 ttccaggaaa aaagttttaa aacccatgca tgagattaga actatcgaga gtgagcaaga
     1561 tatacaagat tttattataa aattattgag agggtttacg ctaacttatg gacagtggcg
     1621 taaagaattt caatcaagat tcttcccagt tcattattat ggtctgaatt ttaatcaagg
     1681 aattgcgttt tcagatttag ctatcctttg gagttatcaa caactagcta agaaagtaaa
     1741 aaatttcaag tttgatgact attatgagat tcgaacacag gttattaatg aggcagtaaa
     1801 taattttaag aaatcgtccc tttctggtct ttttgatggt aaaattggta caatctggct
     1861 catttatgaa tttggggaga tagatcgggc agttgaactt tttacaactc attttataga
     1921 gatatttgag aattcacaaa ataaaaattt atatagtggg caggctggaa ttttactggt
     1981 tggactgtat tttcttagta aagggggaat tgataataaa ctaggagaag aaatactaat
     2041 taggcttaga gaatatactt taaattatat agaaaatcca gaaacttttt gtaaagttgg
     2101 cgctagtgat gttcagagta acgatcctta tgagaatttt ggtggattac tatatggtca
     2161 cgcaggggta gcttggctct tcggtgaagc ttataaatta actggtgaaa gtatctataa
     2221 aaatggtcta gaattggctg tagataaaga attagttgct tataaagtag atagtaataa
     2281 ttcattgcag tacagccaag gtcatagatt actaccatat ctagcaactg gaagtgctgg
     2341 cctgctttta cttattaata gaaataaaga aatcttgtca agcaaatact taaaatattt
     2401 aacttcttta gagagggcaa ctgatgtagt tttttgtgta ttaccaggtt tatttaacgg
     2461 attttgtggt cttgaagttg ctaataatat atatagtgat atcgatgata acttttcagg
     2521 acaaaagaaa ttaattgaac aactttatag atatttgtgt gtaattgaag aaggatttgt
     2581 tattgcggga gataatggtt taaagataac aacagatatt gcttcgggat ttgcgggtgt
     2641 tgcaattgga ttggtatcaa taatggataa taaattgacg attcttcctc aaatataata
     2701 tttagatacc attattaagg ggtcatactt gtgaatcaga gtaatgaaat atttttaaat
     2761 acaatacagg aaaaaacaca ctataagagg tctatctctt catcatttca ggaattaaaa
     2821 aaatggaatt ctttgatatt taggagaggg cgatattggt accaatttga taattggagt
     2881 atacccaata ctggtgtaat aaaggaatgg tatgtcgaag ataatgactg gattcctaag
     2941 gttagttctt ccagtttaga caattcaaat tcacttaaaa ttgtctttga tgtggaaaaa
     3001 tatactttgc cagatgatag tatcttacag gatgttagga tttcatctga tgagagttat
     3061 atagttttgg ttgtatcctc actgcgtagc actaatttaa ttggaataaa aaaatatact
     3121 atggaagagt tatttatcat tgaagatatt tcagtagaaa gttcgttcta tttgggtaaa
     3181 ttcggtgtta tgtatactcg ctccaaagag tacgggaggc caagtaagtt attctataaa
     3241 tcttttgata gctttacaga agaggaactg tttgaagaaa acgaatgctc ttttcgatta
     3301 aaaatagtcc acattgatag caataattgt tttgtaaagt cagtagactt tcagaaaggc
     3361 aggatttttc tatacagttt cgaccggacg ggttttgtta gacactctta cacagaaacg
     3421 gtagccccaa cacctagaga tatcgctcta tttagtacag aaaaagcaca gtactttctt
     3481 gggctctctt caactgaaga aaagaaagat caactaattc taagggaaac ttcttcggga
     3541 gacagagttt ctattactat accatatcaa gatagggcta gaagagttca ctgtatagga
     3601 cgttatatcc ttttagactg ttcaaacgca gcgaattccg tcttttatct tgctacattt
     3661 aaaaataata gtttgaggga gttgagtgtt aataagataa catttgatga aaagacaaca
     3721 ctttatgaaa attcattttc tgatcgtgtt cttctgtttt tagagaggag aactttttac
     3781 gaaaaaatac ttagttttga tttaatagaa aatacattaa aaactgaatt tgaaagaccc
     3841 atcataaaat cgaataatac taaatatttt tctaaggtga tttggactaa aaaagacagt
     3901 tatgatgtaa gcataccgat ttctttattt tggaaaagtg aagatacgga tgagctccca
     3961 agaagaaaaa aatgtattct aagtgtctat ggggcttatg gtaagaatga taattctgat
     4021 ttagatgaaa ttatgttatc tataatagat gcaggtttta tttatgctat agttcatgta
     4081 agaggtggag gctatttggg tggtgaatgg tatcgctcag gaaaggcgtt aaacaaatgg
     4141 aattctatca gagattttat tgagggagta aattatttaa gggaaaatga tgtaattgac
     4201 agtaagcgat taggtttaat aacttctagt gcaggtggaa taattgctgg tgcggtgttg
     4261 aacgaggaaa aaaatttatt gcaaagcatt ctcttatttt cgccatttat aaatccttat
     4321 gatacacttc agaatccaaa tgatcctctt tctaagaccg aaatagcaga gtggggagat
     4381 attagagacc ctgaagtaaa ggcttatata aagtcatatt cgcctatgca aaatattgaa
     4441 aaggcacgag actcaaatac tgttatagtt aatattttgg gtgagaaaga cccatatatt
     4501 aataataacg aagtgataga gtggtcaaag aaattaaatt ctattggagt taaaagtttg
     4561 ttgtatttaa acaaagcagc tggtcatgga ggttttactc catcagatgt tctcttaatg
     4621 attgatactt taaattat
//
LOCUS       DAVLHB010000085         4173 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLHB010000085 DAVLHB010000000
VERSION     DAVLHB010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.085"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..1074
                     /locus_tag="VXE36_002025"
     CDS             <1..1074
                     /locus_tag="VXE36_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0780257.1"
                     /translation="SASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     SISASESASTSASASASTSASASASTSASASASISASESASTSASASASASTSASASA
                     STSASASASTSASASASTSASASASTSASTSASTSASASTSASVSASTSASASASISA
                     SESASTSASESASTSASASASTSASESASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSVSNSANHSNSQVGNTSGSTGKSQKELPNTGTESSIGSVL
                     LGVLAAVTGIGLVAKRRKRDEEE"
     gene            1135..3219
                     /locus_tag="VXE36_002026"
     CDS             1135..3219
                     /locus_tag="VXE36_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0780258.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIITQTYKNIEIVVVNDGSTD
                     ASGEICKEFAEMDHRITYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIELDYVET
                     LYKKITEYQADIAVGNYYSFNESEGMFYFHISGDSYYEKVYDNVSIFENLYETQEMRS
                     FALISAWGKLYKARLFEQLRFDIGKLGEDGYLNQKVYLLSEKVIYLNKSLYAYRIRKG
                     SLSRIWTEKWMHALVDAMSERITLLANMGYPLEKHLAIYRQMLEFSLSNGQASGLSDT
                     ATYKEFEMKQRLLNQLSRQEESEKKAIVLAANYAYVDQVLTTIKSICYHNRSIRFYLI
                     HSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFVQEDK
                     ALYLDCDLVVTKNLDDLFATDLQGYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKK
                     ENMTQKLIDLTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEG
                     QDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKE
                     PFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYL
                     VDVDNELIETSQVLLDINHGEKTEEILDQFANLGKPILSFENTKTYEVGQEAYAVDQV
                     QAMIEKLREISK"
     gene            3216..4094
                     /locus_tag="VXE36_002027"
     CDS             3216..4094
                     /locus_tag="VXE36_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEV0780259.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFHIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEIFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFQINNKAD
                     LIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKERR"
BASE COUNT         1318 a          792 c          883 g         1180 t
ORIGIN      
        1 tcggcttcag caagcacaag tgcctcagcg tcagcatcaa cgagtgcttc agcttcagca
       61 agtaccagtg cgtcagcatc tgcaagtacc agtgcctcag cctcagcaag cacaagtgct
      121 tcggcttcag caagtatctc agcgtctgaa tcggcatcaa cgagtgcgtc agcctcagca
      181 agtactagtg catcagcatc agcatcaacg agtgcatcag cctcagcaag tatctcagcg
      241 tctgaatcgg cctcaaccag cgcctcagcc tcagcttcag cgtcaacgag tgcgtcagcc
      301 tcagcaagta caagcgcctc agcttcagca tcaacaagtg cttcggcttc cgcatcaacc
      361 agtgcctcag catcagcaag caccagtgca agtacgtcag caagcacgtc agcctcagca
      421 agcaccagtg cttcagtctc agcctcaacg agtgcctcag cctcagcaag tatctcagcg
      481 tctgaatcgg cctcaacaag tgcctctgaa tcggcatcaa ccagtgcatc ggcttcagca
      541 agtacaagtg cgtctgaatc tgcatcaacc agtgcttcag cctcagcatc gacaagtgca
      601 tcggcctcag cctcaacgag tgcctcagcc tcagcgtcaa cgagtgcttc ggcttcagca
      661 agtaccagtg cgtcagcttc agcgtcaacc agtgcgtcag cttcagcctc aacgagtgcg
      721 tcggcttcag caagtacaag tgcgtctgaa tctgcatcaa ccagtgcgtc agcttcagca
      781 tcgacaagcg cttcagcttc agcgtcgaca agtgcgtcag cctcagcatc gacaagcgct
      841 tcagcttcag catcgacaag tgcttcagca tcagcaagta catcagtttc aaattcagca
      901 aaccattcga actcacaagt tggaaatact tctggatcga caggtaaatc ccaaaaagaa
      961 ttgcctaata caggtactga gtcgtcaatt ggatctgtgt tacttggagt tctagcagct
     1021 gttacaggta ttggattggt tgcgaaacgc cgtaaacgtg atgaagaaga gtaagacaac
     1081 ctgtaaagtt aggctaaact aactcgcgca cataaatcaa ggagaaaatt gctagtggat
     1141 gataaaataa cggtcattgt accagtatac aatgtggaaa actatctgag gaagtgccta
     1201 gatagtatta ttactcaaac atataaaaat attgagattg ttgtcgttaa tgatggttct
     1261 acggatgctt caggtgaaat ttgtaaagaa tttgcagaaa tggatcaccg aattacctat
     1321 atagaacaag aaaatgctgg gctgtcagct gcacgaaaca ccggtctgaa taatatgtcc
     1381 ggaaattatg tgacctttgt ggattcagat gattggattg agttagatta tgtagaaacc
     1441 ctatataaaa aaataacaga atatcaagct gatattgcag ttgggaatta ctattctttc
     1501 aacgaaagtg aaggaatgtt ctactttcat atatcaggag actcctatta tgagaaggta
     1561 tatgacaatg tttccatctt tgagaatttg tatgaaactc aagaaatgag gagtttcgct
     1621 ttgatatctg cttggggtaa actctataag gcgagattgt ttgagcagtt gcgctttgac
     1681 ataggtaaat taggagaaga tggttacctc aatcaaaagg tatatttatt atcagaaaag
     1741 gtaatttatt taaataaaag tctttatgct tatcgtatta gaaaaggtag tctatcaaga
     1801 atttggacag aaaagtggat gcatgcattg gttgatgcca tgtccgaacg cattacgcta
     1861 ctagctaata tgggttaccc tttagaaaag catttggcga tttatcgtca aatgttggaa
     1921 ttcagtctct ccaacggtca agctagcggt ttatctgaca cagcaacata taaagagttt
     1981 gaaatgaaac aaaggctttt aaatcagcta tcgagacaag aggaaagtga aaagaaagcc
     2041 attgtcctag cagcaaatta tgcctatgta gaccaagttt taacgacaat caagtctatt
     2101 tgttatcata atcgttcgat tcgtttttat ctgattcata gcgattttcc aaatgaatgg
     2161 attaagcaat taaataagcg cttagagaag tttgactcag aaattattaa ttgtcgggta
     2221 acttctgagc aaatttcatg ttataaatcg gatattagtt acacagtctt tttacgctat
     2281 ttcatagctg atttcgtgca agaagacaag gccctctact tggactgtga tctagttgta
     2341 acgaaaaatc tggacgactt gtttgctaca gacttacaag gttatccttt ggctgctgtt
     2401 agagattttg ggggcagagc ttattttggt caagaaatct ttaatgccgg tgttctcttg
     2461 gtaaacaatg ctttttggaa aaaagagaat atgacccaaa aattaattga tttaaccaat
     2521 gaatggcatg ataaggtgga tcaggcagat cagagcatct tgaatatgct ttttgaacat
     2581 aaatggctgg aattggattt tgattataat catattgtca ttcataaaca gtttgctgat
     2641 tatcaattgc ctgagggtca ggattatcct gctattattc actatctttc tcatcggaaa
     2701 ccgtggaaag atttggcggc ccaaacctat cgtgaagttt ggtggtacta tcatgggctt
     2761 gaatggacag aattgggaca aaaccatcat ttacatccat tacaaagatc tcacatctat
     2821 ccaataaagg aacctttcac ttgtctaatc tatactgcct cagaccatat tgaacaaatt
     2881 gagacattgg ttcaatcctt gcctgatatt cagtttaaga tagcagctag agtaatagtt
     2941 agtgatcgat tggctcagat gacaatttat ccaaacgtga ctatatttaa cggaattcac
     3001 tatttggtag atgtcgataa tgaattgata gaaaccagtc aagtactttt agatattaat
     3061 catggcgaaa agacagaaga aattctcgat caatttgcta atcttggcaa gcctatctta
     3121 tcctttgaaa atactaaaac ctatgaagta ggtcaggagg catatgctgt tgaccaagtt
     3181 caagcaatga ttgagaaatt gagagaaata agcaaatgaa gaaaaatcat ttagtaggag
     3241 atgctctgat tttgacggtt agtgatcaga ttgaagagtt ggattatctc cttgaatcct
     3301 tgccaaatat ctgttttcat attgcagcac ctgttcaatt ttccgagaaa atccgtagct
     3361 tagaaacgaa ctataatgtc cgtctccgaa cgattacaaa tgaagaacag ctaaactttc
     3421 tagtcgatac ctgtgacttt ttactagata tcaatcactt tcaagaagta gatgctattg
     3481 tctccaagtt tgtacaggct ggaaaatctg tctttgcatt tgacaataca gtccatggaa
     3541 atcaggggca ggaaattttt ctatcaagta caccagacaa attggtttct agagtgagag
     3601 actatctgaa tgaagtcaga gtaggcacca atcatcaaga gaaaatcatt caagatggga
     3661 cttggaatgt ctttcaaatt aataataaag cggatttaat tgtaggagca aatgtcatct
     3721 gcagaaattt tgaaaatttc catgtctctt ctggtaagtt aatcctgcat gatggtgttt
     3781 ttatcaacaa ctcttgtagt tttaactgta tggaaagaat tgaaatcgga gctggtacca
     3841 tgatgggaga gggtgttcgt ttttatgatc acgaccatat ttataccgct gaaaagattg
     3901 aaaagtggca gtggactaca gcgccgatta gagttggcag agactgctgg ataggaagta
     3961 atgtcacgat tttaaaagga gtgacgattg gggataatac cattattgga gcaggttgtc
     4021 tcatacgcaa tgatattcca tcaaacagtg tagtttataa taatggaaat cttgttgtaa
     4081 aagaaagaag ataatttgga gttatggata caaaaaaaag caatcgtttt aggggcagat
     4141 aataattatc gtgacaaatt ggaaacaact att
//
LOCUS       DAVLHB010000086         4108 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLHB010000086 DAVLHB010000000
VERSION     DAVLHB010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4108
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.086"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(274..444)
                     /locus_tag="VXE36_002028"
     CDS             complement(274..444)
                     /locus_tag="VXE36_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780260.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(457..1035)
                     /locus_tag="VXE36_002029"
                     /pseudo
     CDS             complement(457..1035)
                     /locus_tag="VXE36_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(1052..1855)
                     /locus_tag="VXE36_002030"
                     /pseudo
     CDS             complement(1052..1855)
                     /locus_tag="VXE36_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(1948..2106)
                     /locus_tag="VXE36_002031"
     CDS             complement(1948..2106)
                     /locus_tag="VXE36_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0780261.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(2177..2606)
                     /locus_tag="VXE36_002032"
                     /pseudo
     CDS             complement(2177..2606)
                     /locus_tag="VXE36_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2701..3141)
                     /locus_tag="VXE36_002033"
     CDS             complement(2701..3141)
                     /locus_tag="VXE36_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0780262.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            3132..3440
                     /locus_tag="VXE36_002034"
                     /pseudo
     CDS             3132..3440
                     /locus_tag="VXE36_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3595..3918)
                     /gene="tnpB"
                     /locus_tag="VXE36_002035"
     CDS             complement(3595..3918)
                     /gene="tnpB"
                     /locus_tag="VXE36_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0780263.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(3899..4084)
                     /locus_tag="VXE36_002036"
     CDS             complement(3899..4084)
                     /locus_tag="VXE36_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780264.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
BASE COUNT         1253 a          827 c          698 g         1330 t
ORIGIN      
        1 atcaaagagc aaactaggaa gcgagccgca ggctgtactt gagtacggta aagcaaagct
       61 gacgtggttt gaagagattt tcaaagagta ttaaacaaaa agaaaaaccg ctactcctaa
      121 gaatagcgat ttaatcatgt ttttaagcta ctactgtagt tgctctatta tttaagtgtt
      181 atgaataact tcaatatctt taaagctttt tgttagattt ataatttcaa ctatagccat
      241 ctctactcct tagtttacag caaaaaatta tgcttaattc ttattgtttt tgtaaacaat
      301 cagcgaaccc aatactattc cattcaacaa gcctaaagaa ataccatatt caactggaaa
      361 atctaaaaaa attgcaaaca ctattccaat catcacccct agtgaggctg ttgttaaaat
      421 tacatattca ttttctttct tcattttctt tacacctcat ttcctttttg tatataagct
      481 gtagtactct ccaccaagat ccattaagta cttatgattt cctgactcaa caatcttacc
      541 acctttcatt acaaaaataa catccgcatc cttaatcgtt gacaatctat gagctacaat
      601 tatttgagta cagccctgac tttgtatata ctttgttatt ctttcctcat taatagtgtc
      661 taatgcacta gttgcttcat ctaaaattac aatactagga ttatttatta atgcacgtgc
      721 cagtgctatc cgttgccttt gcccacctga aatatttgac cccatctctg agatgatagt
      781 attaaatttc atcggcatag ccatgatttc atcatagatt tgaactgctt tacaaacttc
      841 ctctatcttt tgtgaagtaa cttcgtgctt taaagttata ttatcaagaa tacttcggtt
      901 caataaaaat gaatcctgtg gaactactcc taaattttga cttaatattt ttttatctat
      961 ttgattaata tttacaccat caaataaaac ttttcctgta tcaatcttat ataatcttga
     1021 tggtattttt gataatagac ttcctgcaaa actagaatcc tagttcatga ttgataatac
     1081 cagcaatcaa attcattcgt aatccgaagc gtttagatga tttcgatagg ttgttgaaat
     1141 cattttaaac gtttttactt tggcaaagat gttctcaacc ttgcttctct ccttagatag
     1201 cgcatggtta tagactttat cttcaattgt tagcggtttg agtttgctgg atttacgtga
     1261 agtttgtgct tgaggatata tcttcatgag cccttgataa ccactgtcag ccaagatttt
     1321 accagcttgt ctgatatttc tgcgactcat tttgaacaac ttcatatcat gacaatagtt
     1381 cacagtgata tccaaagaaa caattctccc ttgacttgtg acaatcgctt gagccttcat
     1441 agcgtgaaat ttctttttac cagaataatt cgctaattct ttttttaggg cgattgattt
     1501 ttacttccgt cgcatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaatcg
     1561 taacaccact ttgaacaaga gttacttcaa cccattggct ccgacggatt aagttgcttt
     1621 cgtgaatacc aaaaacagcc gcaatttgtt cataagttcg atattctcgc acatattgaa
     1681 gagtggccat aagaaggtct tctagactta atttaggttt tcgtccacct tttgcgtgtt
     1741 taagttgata agctgttttt aatacagcta acatctcttc aaaagtcgtg cgttgaacac
     1801 caacaagacg cttaaatcgt gcatcggtta gttgtttact tgcttcatca ttcatagaac
     1861 tattatacca tattttgttt cgcaggaagt ctattgaaaa atctccagac tggagaactc
     1921 acggatagtt cctaatctgg agatttctta tttgcacttt tcttgtacaa ctttagtcca
     1981 tggtaaataa gcctctaaaa cctctttgtt tacgagagtt tcctcgtttg gaagacattc
     2041 tagaagatag gatagatatt tctcgctatt taattgatga cgtttagctg tttccaacaa
     2101 actcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata accaccctcg
     2161 cttttttaaa ctgagcttag gctaaaagag tccactggac tcttttactc cgtcccataa
     2221 ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt ccgtctttca
     2281 aaatggtctt aaaggtttct tcatacttga ggctgtattc aattgccctt cctagttttg
     2341 aacctgctaa aactgactga cgccggcact aagcaaagaa gtcttccatt aagggctgga
     2401 gatgttcttg acgtttctgt agtcgttcat cagctggcaa agcctcccag tctctttcca
     2461 aggaaaataa ctgatcacaa taagctaaac ctttagctcc taaggatgat ttatccgctt
     2521 gcttgggggg gcgcttcaaa aaacttcctt ctcacatgcg cccaacatcc aacaagttca
     2581 gcttcttcca gttgacgata agcagacgag cggttcgaag tttaccaagc ttagcgtcgc
     2641 cttgctccta aaccttggac tgctatcgca taggcagaac tagaggacta aagtcctaag
     2701 ttactgccgc aaaatatcac aatgcacata gccagaataa tctcctagga attcttgtac
     2761 tactgaacca cttcgacact gatcatggtg gtaaagcgta atcccttgtt tctctgcttt
     2821 acctgacaaa aaagtccaat agtaagtcag ctgactatca ctctctagca ccctataaga
     2881 agtttcatcc gcatgaagta agggctgagt caatagtctc tctcgcaaga ggttataaag
     2941 gggctccaaa tagtattgac tcgccttgat atgccaatta gagatttcct tacgtgtgat
     3001 tggtaaaccc atcctagccc aatcttcttc ttggcgataa ttgggtacct tcagattaaa
     3061 cttctgatgg atggtgtgag cgataataga agctgagcca aagttatgcg ctaaaggggc
     3121 tttaggaata ggagatttca caagcttatc cagatgatta tcttttactc gttatggaca
     3181 atgctatatg gcataaatca agtaccttaa agattccgac taatattggc tttgcattta
     3241 ttcctccata cacaccagag atgaacccca ttgaacaagt gtggaaagag attcgtaaac
     3301 gtggatttaa gaataaagcc ttttaaactt tggaagatgt catgaatcaa ctccaagatg
     3361 ttatacaagg actggagaag gaggtgataa agtccatcgt taatcggaga tggactagaa
     3421 tgctttttga aagcagatga gtataaaaag aaagtcctca tttcaataga aatcacgact
     3481 ttctgatgga tttatagtaa aatgaaataa gaacaggaca aatcgatcag gacagtaaaa
     3541 tcgatttcta acaatgtttt agaagcagag gtgtactatt ctagtttcaa tctactatat
     3601 ttttggagtg atagaaaagc ccttcataag ccagtctact tgttctggtg tgagagcttt
     3661 gacatccttt tctgtactta gccaaatcaa tctgccgttc tcaaagcgtt tatatagtag
     3721 ccaaaatcct tgaccatccc agtaaaggac tttaaagcgg tctttacgtc caccacaaaa
     3781 gagaaagact tgaccggaga aaggatccaa ttcaaagtgg gttttaacca gataagccag
     3841 tgaatcgatt ccttgtctca tatcagtttt cccacacacg agatagacct cccctaggct
     3901 agatagatga attgtcatag agcaacacct tatccaaaag ctgttctacc atttcgagat
     3961 tgagagattg aaaaaaactt acttcaagct tgccaatacg aattttaagc agaatatcat
     4021 ttctcttttt agaatcaaaa cgacgagatt gtggaatctc tacaggaaca ataggttgtg
     4081 gcattaaaat atcctccaat agttttac
//
LOCUS       DAVLHB010000087         4029 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLHB010000087 DAVLHB010000000
VERSION     DAVLHB010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.087"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(382..915)
                     /locus_tag="VXE36_002037"
     CDS             complement(382..915)
                     /locus_tag="VXE36_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0780265.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1002..1778)
                     /gene="recX"
                     /locus_tag="VXE36_002038"
     CDS             complement(1002..1778)
                     /gene="recX"
                     /locus_tag="VXE36_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0780266.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(1788..2564)
                     /locus_tag="VXE36_002039"
     CDS             complement(1788..2564)
                     /locus_tag="VXE36_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEV0780267.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQLHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2621..3976
                     /gene="rlmD"
                     /locus_tag="VXE36_002040"
     CDS             2621..3976
                     /gene="rlmD"
                     /locus_tag="VXE36_002040"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0780268.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1281 a          690 c          745 g         1313 t
ORIGIN      
        1 cgattaaatg agctgataga ttaaatatca ttttctctgt taagatattg tttttaaaat
       61 attgtactaa atgattgatg ctatgtggaa atacaaaaaa atgtttttga tacgaagttg
      121 acctgtattt tttatactaa tcattttcgt attttttgta ttaaacgata taagtttgtt
      181 gtaaacttac aaggaataaa gacattaaaa aataacagta tatctatttg ttttatatat
      241 tttacgaatt ttgcataaat ctctttctag taatgtgttg taactctgct ataatagatt
      301 tattcctttt tgtgtttaca caatttattt tatactacca aaaaaacaag gtcaggattt
      361 tgttcctgac ctttgacaac tttaccgatt ctttagttct acatagcgct tgtaccaaat
      421 gtttacatag gcttctgaga aaggaccacg tccattgtta atccaatcaa caagaatttt
      481 gacatgttct tttaaaatat agtccaagtc atcagaataa ttcattttgc gtttgtgacg
      541 ctcgtactct tcaacgtcca agagacgttt ttccccatct gtaaaaattt taacatccaa
      601 atcgtaatca atatacttca gtgcttcttc atccagatag taggggctag ccatattgca
      661 atagtaagaa gttccattat cacgaatcat ggcaatgata ttaaaccaat atttcttgtg
      721 aaagtaaaca atagccggtt ctcgagtgac ccaacgacga ccatcacttt cggtaacaag
      781 tgtatgatcg ttgacaccaa taatggcgtt ttctgttgtt tttagtacca tggtgtcccg
      841 ccaagttcgg tggagactcc catcatgctt ataactttga attgtaataa agtcgccttc
      901 ttttggaagc ttcataacta accaactttc tacaatttat aagtttatca tttactattg
      961 taccataaaa ttataaaatc tgtgaatttc acttggaaat attaaagata ttctctaaga
     1021 gcgcttgcta tatccgaaaa atcgtagccc tttcgtgcta aaacttgagt taaacgctgc
     1081 ttcagttcgt atccttcata ctttcgagca tacttactat attgtttatc aagttccttg
     1141 aagatgagtt cttgagtcgt ttcttggtca acttggctat ctaagtcgtc aaaggcaatt
     1201 ttagcatcag aataagagaa gcccttgtta gtcaagttct ggataatctt atcttgcagg
     1261 gcacgagatg gaagttttcc ctcatatttt ttcaatagtt tattagctac acgttgagca
     1321 acttcagaaa aatcaaattc tttcaagttc tcttctatag tagattttga aatccctttt
     1381 tgagctagtt tctgagtcag cacataagga cccttgtctc ctgaaagttg attggtattg
     1441 atgatagcat aagcgtactg accatcatta atccacttat cttctttaag attagcaata
     1501 acttgagaaa cgatgttttt atcaatatcg tattttttca gatattctct gacttctttt
     1561 tcagtgcgtg ctttaaagga taagtggtag agagcgagat tcttaccata agaaaactgg
     1621 gcaaaatcct gaatctcggt cagttcctct ttactaatga ccttatctcg agacagcata
     1681 aaacggacaa tggtatcttc cgtgatataa gaggtttgct gtccatctag ttccatcaag
     1741 tagagacgtt ttttcttttc aagttttgtg attttcataa tttcctttca tctaaatgct
     1801 tcgaaagctg caacaagtcg tagtttatcc atatttacat attctctacc gtaatagtcg
     1861 agaaataatt cagcatacgt agcatcttgt aggttgtaat gaagggacca aattgcccaa
     1921 aagaggtcga tatgtcggtc actaaaacca gccaatccca agtcaataaa gcaagaaaaa
     1981 tgagaggcat ccttcaagat gaaatttggc aggcaggcat ctccatgaat aaaagcatca
     2041 gctttgagaa tgtaaccttt ctcttgtatc agttggtaag cttcttcacg actgtgaatg
     2101 tgaagttgag gcagaagagt cttgttataa aaagtcccct tctgatagtt ttttaaggct
     2161 ttttctttat aacgcttcag atgattttcc gacggaaaag attgtggttt aagactgtga
     2221 agtttgttta atgcttgagc cagggtttga cagagtcttt cgggttgatt taaaaaagcg
     2281 agagcgttgc tgccaatggc ttctttagtc agaaggaagt ccttatttgc tgataaatag
     2341 gtaatcactg gagttcccaa tccttcagtt tcgaaccaac ttgcaatctt ggcttcttga
     2401 gctaatctgc ctttttgatc tatttttaaa tagtaacctg aatctatata taggacagtt
     2461 gcacttgaat gagaagaact atcagagaga ttagctccct tgatatagct tcgtaattgt
     2521 tcagggaaat ctagtatact aaagcgaggt gtttttgaat tcatgctttt attgtaacat
     2581 attcttaaat atcttagaaa ctccatggta taatagacat atgaatctga aagtgaaaca
     2641 aaaaatacca ttaaaaatca agcgcatggg aattaacggt gagggaatcg gcttttacca
     2701 aaaaacatta gtctttgtac caggagctct caaaggcgaa gatatctatt gtcagattac
     2761 ttctattaga cgcaactttg ttgaagcaaa attactgaag gtcaacaaga agtctaaatt
     2821 tcgaattgtg ccatcttgta ctatttataa tgaatgcgga ggctgccaaa tcatgcacct
     2881 gcattatgat aagcagctgg agttcaagac ggacttactt catcaagcgc tgaaaaaatt
     2941 tgctcctgca ggatatgaaa attatgaaat tcgtccaact attggaatgc aggaaccaaa
     3001 atattacaga gctaagttac aatttcagac tcgaaaattt aaaaatcagg tcaaggcggg
     3061 cttatatgca caaaactctc actatttagt agagttgaaa gactgcctgg tacaagataa
     3121 ggaaacccaa gtgattgcta atcgcttagc agaattactt acttatcacc agattccaat
     3181 cacggatgag agaaaagttc taggtgtccg tactattatg gtccgacgcg cgagaaagac
     3241 cggacaggtt cagattatta ttgttacaaa ccgccagctt aatttaactc aattggtaaa
     3301 agagttggtt aaagatttcc cagaagttgt gacagtagct gttaatacaa atacagctaa
     3361 aaccagtgag atatatggtg aaaagacaga gattatctgg gggcaagaga gtattcaaga
     3421 aggtgtactc aattatgaat tttcactatc ccctcgagct ttttatcaac taaatcctga
     3481 gcaaacagaa gtcctctata gcgaagcagt aaaagcgctg gatgttgata aagaagacca
     3541 tttgattgac gcttattgtg gagttggaac gattggattt gcctttgcaa agaaagtaaa
     3601 aacactcaga ggtatggata ttattccaga agctattgaa gatgccaagc gaaatgctaa
     3661 aagaatggga tttgacaata ctcattatga agctggaacg gcagaagaga ttattcctcg
     3721 ttggtacaag gaaggctacc gagcagatgc tttgattgtt gacccaccac gtacaggtct
     3781 ggatgataag ttattagata ctattcttac ttatgtacca gaaaaaatgg tttatatttc
     3841 ttgtaatgtt tcgaccttgg ctcgtgattt ggtacgctta gtagaagtct atgatcttca
     3901 ttatatccag tcggtcgata tgttcccaca tacagctcga actgaagctg ttgtaaaatt
     3961 aataaaaaaa gtttaaaaaa ggtgttgaca aagtttgaaa agactgtata atagtaagag
     4021 ttgaaaata
//
LOCUS       DAVLHB010000088         3822 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLHB010000088 DAVLHB010000000
VERSION     DAVLHB010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3822
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.088"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..497
                     /locus_tag="VXE36_002041"
     rRNA            <1..497
                     /locus_tag="VXE36_002041"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            549..621
                     /locus_tag="VXE36_002042"
     tRNA            549..621
                     /locus_tag="VXE36_002042"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:582..584,aa:Ala,seq:tgc)
     gene            746..3647
                     /locus_tag="VXE36_002043"
     rRNA            746..3647
                     /locus_tag="VXE36_002043"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            3724..>3822
                     /gene="rrf"
                     /locus_tag="VXE36_002044"
     rRNA            3724..>3822
                     /gene="rrf"
                     /locus_tag="VXE36_002044"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1077 a          785 c         1113 g          847 t
ORIGIN      
        1 caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag tcccgcaacg
       61 agcgcaaccc ctattgttag ttgccatcat ttagttgggc actctagcga gactgccggt
      121 aataaaccgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg acctgggcta
      181 cacacgtgct acaatggctg gtacaacgag tcgcaagccg gtgacggcaa gctaatctct
      241 taaagccagt ctcagttcgg attgtaggct gcaactcgcc tacatgaagt cggaatcgct
      301 agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg ggccttgtac acaccgcccg
      361 tcacaccacg agagtttgta acacccgaag tcggtgaggt aaccgtaagg agccagccgc
      421 ctaaggtggg atagatgatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg
      481 gctggatcac ctcctttcta aggataagga actgcgcatt ggtcttgttt agtcttgaga
      541 ggtcttgtgg ggccttagct cagctgggag agcgcctgct ttgcacgcag gaggtcagcg
      601 gttcgatccc gctaggctcc attggtaaga gatcaccaag taatgcacat tgaaaattga
      661 atatctatat caaatagtaa caagaaaata aaccgaaaac gctgtagtat taataagagt
      721 ttatgactga aaggtcagaa aataaggtta agttaataag ggcgcacggt ggatgccttg
      781 gcactaggag ccgacgaagg acgtgacaaa cgacgatatg ccttgggtag ctgtaagtaa
      841 gcgatgatcc agggatttcc gaatggggga acccaacagg taatacctgt tacccacatc
      901 tgttaaggat gtgaggagga agacgcagtg aactgaaaca tctaagtagc tgcaggaaga
      961 gaaagcaaaa gcgattgcct tagtagcggc gagcgaaacg gcagaagggc aaaccgaaga
     1021 gtttactctt cggggttgta ggactgcaat gtggactcaa agattataga agaatgattt
     1081 gggaagatca gccaaagaga gtaatagcct cgtatttaaa atagtctttg tacctagcag
     1141 tatcctgagt acggcgggac acgtgaaatc ccgtcggaat ctgggaggac catctcccaa
     1201 ccctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     1261 ccccgggagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt tcgagcccgt
     1321 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttat gatgcgaggt
     1381 taagttgaag agacggagcc gtagggaaac cgagtctgaa tagggcgcct tagtatcatg
     1441 acgtagaccc gaaaccatgt gacctaccca tgagcaggtt gaaggtgcgg taagacgcac
     1501 tggaggaccg aaccagggca cgttgaaaag tgcttggatg acttgtgggt agcggagaaa
     1561 ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc tagcgtcgac
     1621 attagagatt cttggaggta gagcactgtt tgggtgaggg gtccatcccg gattaccaat
     1681 ctcagataaa ctccgaatgc caatgaatta tggtcggcag tcagactgcg agtgctaaga
     1741 tccgtagtcg aaagggaaac agcccagacc accagctaag gtcccaaaat aattgttaag
     1801 tggaaaagga tgtggggttg cacagacaac taggatgtta gcttagaagc agctattcat
     1861 tcaaagagtg cgtaatagct cactagtcga gtgaccctgc gccgaaaatg taccggggct
     1921 aaaacaattt accgaagctg tggatacctt tataggtatg gtaggagagc gttctatgtg
     1981 tgatgaaggt ataccgtgag gagtgctgga acgcatagaa gtgagaatgc cggtatgagt
     2041 agcgaaagac aggtgagaat cctgtccacc gtaagactaa ggtttccagg ggaaggctcg
     2101 tccgccctgg gttagtcggg acctaaggag agaccgaaag gtgtatccga tggacaacag
     2161 gttgatattc ctgtactaga gtatgtagtg atggagggac gcagtaggct aactaaagca
     2221 gacgattgga agagtctgtc taagcagtga ggtgtgaatt gagtcaaatg cttaattcta
     2281 taacattgag ctgtgatggg gagcgaagtt tagtagcgaa gttagtgacg tcacactgcc
     2341 aagaaaagct tctagcgttt aaacatactc tacccgtacc gcaaaccgac acaggtagtc
     2401 gaggcgagta gcctcaggtg agcgagagaa ctctcgttaa ggaactcggc aaaatgaccc
     2461 cgtaacttcg ggagaagggg tgctgactta aagtcagccg cagtgaatag gcccaagcaa
     2521 ctgtttatca aaaacacagc tctctgctaa atcgtaagat gatgtatagg gggtgacgcc
     2581 tgcccggtgc tggaaggtta agaggagtgc ttagcgtaag cgaaggtatg aattgaagcc
     2641 ccagtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct tgtcgggtaa
     2701 gttccgaccc gcacgaaagg cgtaatgatt tgggcactgt ctcaacgaga gactcggtga
     2761 aattttagta cctgtgaaga tgcaggttac ccgcgacagg acggaaagac cccatggagc
     2821 tttactgcag tttgatattg agtgtctgta ccacatgtac aggataggta ggagtctaag
     2881 agatcgggac gccagtttcg aaggagacgc tgttgggata ctacccttgt gttatggcca
     2941 ctctaaccca gataggtgat ccctatcgga gacagtgtct gacgggcagt ttgactgggg
     3001 cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc cctcagaatg gttggaaatc
     3061 attcgcagag tgtaaaggta taagggagct tgactgcgag agctacaact cgagcaggga
     3121 cgaaagtcgg gcttagtgat ccggtggttc cgtatggaag ggccatcgct caacggataa
     3181 aagctaccct ggggataaca ggcttatctc ccccaagagt tcacatcgac ggggaggttt
     3241 ggcacctcga tgtcggctcg tcgcatcctg gggctgtagt cggtcccaag ggttgggctg
     3301 ttcgcccatt aaagcggcac gcgagctggg ttcagaacgt cgtgagacag ttcggtccct
     3361 atccgtcgcg ggcgtaggaa atttgagagg atctgctcct agtacgagag gaccagagtg
     3421 gacttaccgc tggtgtacca gttgtcttgc caaaggcatc gctgggtagc tatgtaggga
     3481 agggataaac gctgaaagca tctaagtgtg aaacccacct caagatgaga tttcccatga
     3541 ttatatatca gtaagagccc tgagagatga tcaggtagat aggttagaag tggaagtgtg
     3601 gcgacacatg tagcggacta atactaatag ctcgaggact tatccaaagt aactgagaat
     3661 atgaaagcga acggttttct taaattgaat agatattcaa ttttgagtag gtattactca
     3721 gagttaagtg acgatagcct aggagataca cctgtaccca tgccgaacac agaagttaag
     3781 ccctagaacg ccggaagtag ttgggggttg ccccctgtga ga
//
LOCUS       DAVLHB010000089         3774 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLHB010000089 DAVLHB010000000
VERSION     DAVLHB010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.089"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            123..452
                     /locus_tag="VXE36_002045"
     CDS             123..452
                     /locus_tag="VXE36_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0780269.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(620..1669)
                     /locus_tag="VXE36_002046"
     CDS             complement(620..1669)
                     /locus_tag="VXE36_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0780270.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSFRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(1666..2397)
                     /locus_tag="VXE36_002047"
     CDS             complement(1666..2397)
                     /locus_tag="VXE36_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780271.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            2465..2875
                     /locus_tag="VXE36_002048"
     CDS             2465..2875
                     /locus_tag="VXE36_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0780272.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTIFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            2885..3172
                     /locus_tag="VXE36_002049"
     CDS             2885..3172
                     /locus_tag="VXE36_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780273.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            3336..3575
                     /locus_tag="VXE36_002050"
     CDS             3336..3575
                     /locus_tag="VXE36_002050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780274.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
BASE COUNT         1262 a          827 c          741 g          944 t
ORIGIN      
        1 ggggtgaata attggggatt aaagatttga ataaaaaaaa agaattaaaa gtgataaact
       61 aacagtatca aaacacagtt gccagaagta agactggcac ccagattaaa ggaggcattc
      121 ccatgacaga tacagacccc atcaaaagag ctcagacttt gattactgac ttaaacaaag
      181 cctaccaagc atgcaaacag gcaagcgctg acgacgtccg ctttcaggag caattaaact
      241 ctattcttgg ttttctagcc aaggctgaaa cagtggataa tcgattcttg attgaactgg
      301 aaaaatttta ccagacttcc agtcttctca tgggactcag cgctcttgat ccagatgctc
      361 caactcgcgc tgcttggcga gcctatgacc gcttccactt tgaccaagtc aaaaccaagt
      421 taatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta
      481 cggtaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtataagt ctctacggac
      541 caaccattat cctgtagtaa caaaaaagaa gttgagacag actgaactca acttcttttt
      601 tagtgtcgta tcagcaatgt tagtcctgca tctgacgttt tacctgataa ggcaaataca
      661 agactagtaa aaccaaacca gctcctagta aggctagaag ggccagtttt tcttggaagg
      721 taatcaagcc aacaactaat tccacaagta aaacaaaact ggtcaatcct cgaactacct
      781 cctgtaagcc tttttccttt tgccccttgt ccagcggaaa gagttgggtc aaatactggt
      841 agtcaaaggc atgatagagg gccagcaact ggaagagcaa gaggtagtta aagagaacta
      901 ccactgctgt cgcaatccaa gcttgctcga taaaaacctg cgccagtacg gaaagtaaga
      961 gaagacgaaa actgagagca aagaggtcgc catttcgcag ataagaacgc agatagagat
     1021 tttgccaaat cttcccaggc accttctgaa cagcctttaa gataaagtcc agataggcac
     1081 gacgcttgac actgtttgaa attcccttga cctgcgtaaa gagggcaaag aaacgaagca
     1141 agacttgctt acgcttgctt tcttgagaaa taagatagtc ccagtccagt ccagtttcag
     1201 tgaaaaattt gctggccttt tgacgaaagt ggaaatattt tcctaccccc aataaaagca
     1261 catagagcag aaaaactggc aagccataac ccattgctaa aaacaagggc gcaaataaca
     1321 gcaagaaaag ggtctgtaca aagagccaaa agactaggga aatgccagtt tgacgcttga
     1381 gatggagctt gatttcctct tctccaacta agagaaagag cttgtctgga gcctccatat
     1441 aggtggcaat tcctccccaa agtaaaagta aaacagacgt aattcctaca aacaaaagga
     1501 taggccaatg attttcagga aaatgttgta agagttgact gtactggtag gctagaaagc
     1561 ccaacaggac aagcaggaac aagacaaagt ggtcattgag cacatagcgc agataaccaa
     1621 gacactcctt acgaaaggcc tgctttctct ttaaaaacaa gtctttcata ggtcctcctc
     1681 ttttgtcaga gccaagtaaa tatcattcaa actagcctca ggcatatcaa aggcttcgcg
     1741 tagttgcagg agattgcctt tggcacgcac ctctcccttg tgaagaatga caaaggcatc
     1801 acacatcttc tccgccgaat ccagcacgtg ggtactcatg agaatagact tgcccttttg
     1861 cttctccact tccaaaagct gaatcaaatc agaaatagcc agcggatcaa gaccaaggaa
     1921 aggctcatcc acgatgaaaa gacttggatc caccacaaaa gcacagataa tcatgacctt
     1981 ctgcttcatc ccttttgaaa aatgaacagg gaaccagtct aatttctgtt ccaaacggaa
     2041 catttttaac aagggctcta ctcgttcgaa agccactttt tgctcaatac cgtaagccat
     2101 agcaaccgtt tcgatatgct ctctgagggt caattcctca tacagactag gcgtctcagg
     2161 aatgtagcca atctgcttgc ggtagctagt cgcatctcct tgcagagtca ggccattgat
     2221 attgatggag ccactataag gtgccaacag accgataatc tcattgatcg tcgttgattt
     2281 cccagcacca ttgagaccaa tcaaaccgac caactgccca ctttcaacag taaaggacac
     2341 atctttcaaa acaggaacat gaacatagcc acctgtcagg tttttaattt ctaacatatt
     2401 ttctccaaat ctggtataat gtagctatat tatatcaaaa ttcagtacag tagaggtaga
     2461 ttttatgtca gattgcattt tttgtaaaat catcgcaggg gaaattcctg cttcaaaagt
     2521 atatgaagat gagcaggtcc ttgcctttct tgatatctct caagtaacac taggacacac
     2581 cttggtcgtg ccaaaagaac actatcgcaa tcttttggag atggatgcta cgagcgccag
     2641 ccaactcttt gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca ctaaggctgc
     2701 tggtatgaat atcatttcca actgtgaaga agtcgctggt caaacaattt ttcatactca
     2761 cgttcacctt gtgcctcgct acagtgctga cgatgacctc aagattgatt ttatcgccca
     2821 cgaaccagac tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg cttaaggagt
     2881 tgctatgaaa ttatccaacc tactgctatt tgcaggagct gcagccggaa gttatctggt
     2941 tacaaaaaat cgccaaacca tcacagatga agtcttgaat accactgacc gcgttcaagc
     3001 tatcaaggac gatgtggata ttatccaaaa tagcctacaa atcatcgacc agcaaaaaga
     3061 acttatcaag gaataccaag aagacttgac ttacaagttt aaggtcttgg aaaaggatat
     3121 ccagactaga ctagctgtga taaaagaaat gcagggaact gaagataagt aaaaagagcc
     3181 ccccccggct cttttttaaa acgtaaacaa gttatagtga attgaattta gaatagcaca
     3241 ccatagtttc taaagcattg ttagagatta ctttaaaatc ctcttatcaa tttgttcata
     3301 ttctatttca atctattata tatatcccat caactatgca tcataattta ggtaactcat
     3361 actcaataaa aatcaaaaag caaactagaa agctaggcac agactgctca aaacaccgtt
     3421 ttaaggttgt ggatagaact gacgaagtca gctcaaaaca ctgttttgag gttgtggata
     3481 gaactgacga agtcagtaac catacccatg acaagccgac gctgacgtgg tttgaagaaa
     3541 tttttgaaga gtatcattca ccatttcaca actaaatcga agactttctg ccgtaatgaa
     3601 aacacctgaa acagcttggt ttcagctgtc cggaaacttt aagacttagg ttcaaagttt
     3661 aggtatggaa cttcgaagga ggtcgctacc gtccgtcatt acttaggaaa gtcttaaaaa
     3721 atctataaag taaaaagagc ccgacagctc tttttgttta tactcaatga aaat
//
LOCUS       DAVLHB010000090         3493 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLHB010000090 DAVLHB010000000
VERSION     DAVLHB010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.090"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..335)
                     /locus_tag="VXE36_002051"
     CDS             complement(<1..335)
                     /locus_tag="VXE36_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780275.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGD"
     gene            complement(349..1062)
                     /locus_tag="VXE36_002052"
     CDS             complement(349..1062)
                     /locus_tag="VXE36_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0780276.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1521..1901)
                     /locus_tag="VXE36_002053"
     CDS             complement(1521..1901)
                     /locus_tag="VXE36_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV0780277.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2323..>3493)
                     /gene="phtB"
                     /locus_tag="VXE36_002054"
     CDS             complement(2323..>3493)
                     /gene="phtB"
                     /locus_tag="VXE36_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV0780278.1"
                     /translation="HKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEA
                     LDNLLKRLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKY
                     TTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPS
                     TDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNI
                     KFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQAD
                     TNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQVETEKVKEKL
                     REAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT         1034 a          701 c          584 g         1174 t
ORIGIN      
        1 aaatctccca tacagccatt acgattcata ttgaggctat attttcgatt agtaagataa
       61 ttcggaaata tatttcctat tactctaaga ttatctactt gtgaatccct tctcccaata
      121 taatcccctt ctttgactaa tgatggagat ttccaagtaa aaattaaatc gccagagaaa
      181 tttttcttat caaaaaactt aaaaagagat tgataaatac tatttgctaa ttgacaagtg
      241 tcagatgtaa attcataatt aacagcttca ttaaaatcaa cttcagacat ttcaatgtac
      301 tcttcaatag taatattagc tttttttgta gtcattagct aatctccttt aaaatgtgat
      361 cttttcaaga atatttttat ctaaacaatc cagcaagtct tggtaagaat agacttcgta
      421 agtcggctgg gcttgtgtgt gattttcgag gtgatgagga ttataccaga tagtgtcaat
      481 ccccgcatta ttgccacctt gaatgtcggc ggttagagaa tctccaatca tcagcgtctt
      541 ttctttacta aatccagcaa tttgctggcc aatcttttca taaaagagag catccggctt
      601 ttgagtttgc aactgttctg agataaagac ttgattgaaa taaggtacta gaccagattg
      661 agccaaacgt cctgtctgaa tggcagtaat gccatttgtc gcagcataca agttataatc
      721 acgctcaatg aggctgtcca agagatcatg agcgcccgat agtgtttgtc cctgctgagc
      781 gagataaaat tggtaacgct gggcaagaaa actaccgtct ttttcctgtc caaaatgaga
      841 aaataaacga gaaaagcgcg tgttaaccag ctcttgttta ctgattttct tcagctccaa
      901 gtctttccag agagccttgt tcataggaac gtaataatct ttataagcct gaatatccgc
      961 aactccttct tcttttagaa gttgggtcaa agccacatcc tcagcagcat caaaatcaag
     1021 aagagtgtgg tcgaggtcga agagtagaaa tttgtagaac aatttgaggt tttcctttct
     1081 gaaaattcat taagaacatt atatcataaa gcacctcata caattaacta atttaatcac
     1141 ttaaaaaaaa ttcgaacact ttctatacaa ctgacagctc aaatctttca gaatagaaca
     1201 atactaacta tcgagcaccc cgtcttcata aatatatgtg taattctaga cctagaattc
     1261 ctataaacta aatgctttca tactcttcca agtaattgat tgccttaaat tttaattttt
     1321 gaaggattct aaagctagaa tagccccatc acaatcagtt ttgattgatt cacaatttag
     1381 aaacactata gtttcactcc tgttaaaata aaaaggaact gcataaagca atccctttct
     1441 gattttgaaa tcatttactt aacattttat agttgagata atcaatagct tacctataaa
     1501 aagagttata gtaaaattcc ttatttattg atttcaagct ccgctaactg tgtttgaata
     1561 actgacagtt ctgcaccagc ctgaagaaga gcagctgcat tataggcacc ttctacaatt
     1621 ggaaccctgt tgatgatgat acttttatca ctgaaatcag tcaccatttt taagttcatt
     1681 ttagcagaac ctaggtcaaa aaaggcaagt aaagtatctg ctggattttc ggaaacaacc
     1741 ctatctactt gatcaaaact cgttccaatt cctccgccct cggttcctcc tacataagta
     1801 atcggaacat ctttagctac tttactaatc agttcaacaa caccttctgc aatgtgtttg
     1861 gaatgtgaaa cgataacaag accaatacca atactttcca tcaaaccacc ccagtttcta
     1921 aaatagcagt aaagagtaat cctgatgaga atgatccagg atcaatatgt ccaagaaacc
     1981 acatgttcct aagacaagag ctaacagact ggccgtcaat aatagtattg ttcttttttt
     2041 catcattact ccttaactag tgtttaactg attaattagc cagtaaatag tttatcttta
     2101 tttacactat ctgttaagat atagtaaaat gaaataagaa caggacagtc aaatcgattt
     2161 ctaacaatgt tttagaagta gaggtatact attctaattt caatctacta tattttgcac
     2221 attttcataa aaaaaatgag aactagaact cacattctgc tctcattttt cgttttcccg
     2281 ttctcctatc ctgtttttag gagttagaaa atgctgctac ctttacttac tctcctttaa
     2341 taaagccaat agtttttcag cttctgccat aatagtattg ttgtcctggg tgccaaatag
     2401 taaattattt tttaatcctg tgagagtctc tttggcattg gacttgataa ttggatcctg
     2461 gatttttcca agtaaatctt cagcctctct cagtttttct ttaacctttt cagtctcgac
     2521 ctgaggttct tctgattcct ctggtgattc ttcttctggt tcctctgttg gttttggaga
     2581 ctctggtttc tcgctttgcg gtttctcttc tcgaggggtt tcttcctcag gtttttctgt
     2641 ctgaggtttc tccgtttgat tggtatcagc ttgaccattt ttgtttcttt gaacatggtc
     2701 gctagcgtta ccaaaaccat tatctgaatg cggacgttcg tttggatgtt cgacatagta
     2761 cttgacagtc gccaaaagat cctcaagagt atacccctta ggtgcctcat aaaggccttc
     2821 gtcaaaccac tcaaatttga tgttatggta atggtcataa tgaggtatga ttaaactacc
     2881 gtttttgact tctacagtat attgaagatt gtaaggcatg cgatcaagtg gcaccttctt
     2941 agctgctttc acgcggttgt agatagcttc tgctcctttt gcctcagtat ttcctgaatc
     3001 ctgatggtct gtcgaaggag gggtcaaacc tttctcttta gcataagcct gggctgccgc
     3061 tctctcagct tcagacaaac tatctttttt aatccagtgg ctatgggtca tatgtggagt
     3121 tacataggca tccccctcat cactggttat atcacgagga tcaaagatat aaccgtcttc
     3181 tgttgtgtac ttgcctgcca acttggctac ttgaatctca tcatcagtgt aggtaatttg
     3241 cgcatttggt tttcctaaac gttctggatg acgaatcgga gctaagaagg caagaatatc
     3301 atccactaac ttgactttat cacttgagac atccttgagt cgtttcaaca ggttatccaa
     3361 agcctcaaaa tcaacttgtc gacctttatt atcaagtaaa tcttggtgaa ttcttgctag
     3421 taagtcataa gccttattgt aaaattctct atcactagat gggaggtcag ttttcttagc
     3481 tcctagctta tga
//
LOCUS       DAVLHB010000091         3405 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLHB010000091 DAVLHB010000000
VERSION     DAVLHB010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.091"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            1..823
                     /locus_tag="VXE36_002055"
                     /pseudo
     CDS             1..823
                     /locus_tag="VXE36_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(856..1196)
                     /gene="tnpB"
                     /locus_tag="VXE36_002056"
                     /pseudo
     CDS             complement(856..1196)
                     /gene="tnpB"
                     /locus_tag="VXE36_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1457..1756)
                     /locus_tag="VXE36_002057"
     CDS             complement(1457..1756)
                     /locus_tag="VXE36_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0780279.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1921..2372)
                     /locus_tag="VXE36_002058"
                     /pseudo
     CDS             complement(1921..2372)
                     /locus_tag="VXE36_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            2454..3108
                     /locus_tag="VXE36_002059"
                     /pseudo
     CDS             2454..3108
                     /locus_tag="VXE36_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            3196..3405
                     /locus_tag="VXE36_002060"
                     /pseudo
     CDS             3196..3405
                     /locus_tag="VXE36_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1075 a          604 c          658 g         1068 t
ORIGIN      
        1 cgtaaccatg catatatgac agttgaggaa gagaaagcct ttcttgcccg ccatttgaag
       61 gctgcagagg caggagaatt tgttacaatt gatgccttat ttcaggctta taaaaaggag
      121 ttaggtcgtt cctacacacg tgatgccttc tatcaactgt tgaagcacca tggttggcga
      181 aatattatgc cacgtccaga acatcctaag aaagcagacg ctcaaaccat tgttgcgtct
      241 aaaaataaaa tctcaattca agaagataag aaagcgcttt aaatatagta gacgttttcg
      301 taaggttcgc ttgatgtacc aagatgaggc tggtttcggt agaatcagta aactgggatc
      361 ttgttgggct ccaataggag taggtccaca tatccatagt cactatatac gagaatttcg
      421 ctattgttat ggagctgttg atgcccatac aggcgaatca tttttcttaa tagctggtgg
      481 atgtaatact gagtggatga acgccttttt agaagagctt tcacaagctt atccagatga
      541 ttatctttta ctcgttatgg acaatgctat atggcaaaaa tcaagtatct taaagattcc
      601 gactaatatt ggctttgcat ttattcctcc atacacacca gagatgaacc ccattgaaca
      661 agtgtggaaa gagattcgta aatgtggatt taagaataaa gcctttcgaa ctttggaaga
      721 tgtcatgaat caacttcaag atgtcataca aggactggag aaggaggtga taaagtccat
      781 cggtaatcgg agatggaata gaatgctttt tgaaagcaga tgagtataaa aagaaagtcc
      841 tcatttcaat agaaatcacg actttctgat agatttattt ttggagtgat agaaaagccc
      901 ttcatcagcc aatctacttg ttcaggtgcg agagctttga catccttttc tgtacttagc
      961 caagtcagtt ttccgttctc aaagcgttta tatagtagcc aaaatccttg accatcccag
     1021 taaagggctt taaagcggtc tttacgtcca ccacaaaaga gaaagacttg accggagaaa
     1081 gaatccaatt caaagtgggt tttaactaca taggctaatg agtctattcc ctacctcata
     1141 tctgtcttac cacaaacaag gtgaacttga cctaaatcac ttagttgaat tatcatagta
     1201 caataccttt cctccgataa ttatttttta tctagtatac tggaagttgg ggaattagga
     1261 tagatacctt gttatgacgc gcttacgtaa cttgtaacta gctgcctagt ttgatctttg
     1321 cttcttcatt gattagcagt agatttcaaa atgataaaaa cgcataatag tgggtgtaga
     1381 aactcttgct actatgcgtt ttgttatgga aagacttatt ggactttctc tcaaatcgag
     1441 tttttactca attttcttac ttgattggga ttgaaattcc aattaatttc tctgagtaga
     1501 gtgtcttgat attggcttca tcaacagagg tcttatcaat tttacgtttc aagaaaaatt
     1561 cttgaatggt ttcgatttca ggctcacgaa tagcacggtg tttgtttgag atgaggattt
     1621 catagtgaag cggagcttgg gtaaaaataa catctgtatt ccctgcagaa taaacctcaa
     1681 caagggttgc atcggtactt tctagttgac tttttacaag ttgcgagtgt gagtttgtcg
     1741 tattgataag cttcataata tttcctccga ttttctaatt ctattataac actttttgaa
     1801 taaagtcgct tgatttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
     1861 gctatacttg agtacggtaa ggcgacgctt acgtgatttg aattttattt tcgaagagta
     1921 ttagccaatc ttatgctgtt ttttccaaga ttcaatggcc catttatggc taccacgttt
     1981 aaggtttttg atagcctcgt caatagggaa ccaggcaata tgattaaagt tttctagtgg
     2041 cttttgtact tctttgaaag gagttgcttc atagaggtag gcaggattgt agtagtaggt
     2101 atcacgatga cgagaataga aatattcgtc agcttgtccg taataggtac caatttctgc
     2161 tgtgaaacca agctcttcaa tcaactcacg ctttagggct tcctgatgat tttcacctgc
     2221 ttcaattttt ccacatggta ggaaccaagc accatttggt tcttgaacaa gaacaatttg
     2281 tttttgttca ggattaggga taactgcata tacgccatag cgagcaatat agtctgtatt
     2341 cacttttttt ctccgaaagt tgggtttgcc attgcatttt cctcattatc tagtatcgtt
     2401 attattatag tgaaatgaac caaaaatagt acacaatgtg gtataatctt tttatggcat
     2461 attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaacaggt agtataacag
     2521 aagcatcaca cgttttccaa atctcacgta ataccattta tggctggtta aagctaaaag
     2581 agaaaacagg agagttaaac caccaagtaa aaggaacaaa accaagaaaa gttgatagag
     2641 atagacttaa aaactatctt actgacaatc cagacgctta tttgactgaa atagcttctg
     2701 aatttggctg tcatccaact accatccact atgcgttcaa agctatgggc tacactcgaa
     2761 aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagccttatt tcttaagaat
     2821 tttaatagat taaagcacct agcacctgtt tagattgacg aaacaggatt cgatacttat
     2881 ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa gaagaggcaa agtatctgga
     2941 agaagatatc agaggatttc tttggttgca ggtctaacaa atggtgagtt aatcgctcca
     3001 ataacttacg aagagacgat gacgagcgac ttttttgaag tatggtttca gaaatttctc
     3061 ttaccaacat taaacacacc atcggttatt atagtaaaac gaaataagaa taggacaaat
     3121 cgatcaggac agtaaaatcg aattctaaca atgttttaga agtagatgtg tactattcta
     3181 gtttcaatct actatattat ggataatgca agattccata gaatggggaa gctagaactt
     3241 ttatgcgaag agtttgggca taaactttta cctcttcctc cctactcacc tgagtacaat
     3301 cctattgaga aaacatgggc tcatatcaaa aagcacctca aaaaggtatt accaagttac
     3361 aatacctttt acgaggctct tttgtcctgt tcttgtttca attga
//
LOCUS       DAVLHB010000092         3387 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLHB010000092 DAVLHB010000000
VERSION     DAVLHB010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.092"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            10..1128
                     /locus_tag="VXE36_002061"
     CDS             10..1128
                     /locus_tag="VXE36_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0780280.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVALVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            1188..1424
                     /locus_tag="VXE36_002062"
     CDS             1188..1424
                     /locus_tag="VXE36_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0780281.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            1421..1834
                     /locus_tag="VXE36_002063"
     CDS             1421..1834
                     /locus_tag="VXE36_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0780282.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            1952..2917
                     /locus_tag="VXE36_002064"
     CDS             1952..2917
                     /locus_tag="VXE36_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0780283.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            2883..>3387
                     /locus_tag="VXE36_002065"
     CDS             2883..>3387
                     /locus_tag="VXE36_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0780284.1"
                     /translation="MSSIHTKNSSLKSKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSS
                     GKFLDKHDRVFEGYPAYGGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWIS
                     DNAIYIKEFKNSDFNLVFLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQ
                     NEFADFVA"
BASE COUNT         1233 a          491 c          647 g         1016 t
ORIGIN      
        1 ggtggttgca tgaagaaggt gaaattaggt gaagtggcta cttttatcaa tggctatgct
       61 tttaaacctc aagattggtc atctgaaggg aaagagatta tcagaataca gaatctgact
      121 aaaacttcaa cagagataaa ttattattcg ggtacgattg ataaaaaata cattgttgaa
      181 gctggtgata ttcttatttc gtggtcgggt acattagggg tttttcagtg gcgtggaaga
      241 tccgcagtgt taaatcagca catttttaaa gtggtttttg ataagataga tatagataaa
      301 tcgtatttta aatatgttgt tgaaaaaggt ttacaagatg ctgtaaaaca tactcatggt
      361 tccacaatga aacatttaac taaaaaatat tttgataata ttatagttcc atatacaaat
      421 ttgggagagc aacaaagaat tgcaagtgag ctggatttgt taagcaagct gattttaagg
      481 agacaagaac aacttgaaga gcttaatcta cttgtaaaat cccgatttaa cgagatgttt
      541 ggggaaaata aaatatttga aagcattgat aacttatttg atattataga tggtgatagg
      601 ggcaaaaatt atcctaaatc agatgagttg tttagtgagg agtactgttt atttttaaat
      661 acaaagaatg ttactaaaaa cggattttca ttcgatacaa agcaatttat cactaaaaca
      721 aaggataaat tacttcgaaa aggcaaactt gagcgttatg atatagtctt gacaacaaga
      781 ggtactgttg gaaatgtagc gtactacgat gaattaataa aatataaaca tttacgtata
      841 aattcaggta tggtaatatt acgtcccaag acaccaaatc taaatcagaa atttattatc
      901 catgttttaa ggaataataa ttatagtcga gtgatatcag gaagtgctca gcctcagtta
      961 ccaattacaa aattaaaaaa aatacttctc ccccttcccc cactagccct ccaaaatgag
     1021 ttcgcagact ttgtagccct ggtcgacaaa tcacaattgg caatccaaaa atctctggaa
     1081 gaacttgaaa ctttgaagaa atctctgatg caggagtatt ttggctgata ttctgccatt
     1141 gtaattacgg taatgatttg ttataatact tcaaaggagg aaatcagatg gtagtaaaaa
     1201 caagaaaaca aggaaattca atcaccatta cgattccaag tgaatttaat attccaagtg
     1261 gtgttaaata cgaagcgaaa ttgttaccaa gtggtgagat tatctttact cctgaagaat
     1321 tggggcagca ggtttcttat gtatctgatg atgcctttga cttaaattta gataaaatat
     1381 ttgacgaata cgacgatgtt ttcaaagctt tggtggaaaa atgacaatct atctgacaga
     1441 aaagcaaatt gaaaaaataa atgctttagc aattcaacgg tattctccaa atgagaaaat
     1501 tcaaacagtt agttcttctg ccttaaatat gattgtgaac ttaccagaac aatttgtctt
     1561 tgggaagtct ctttatccaa caatttttga taaagcaacg atactatttg tccaattgat
     1621 aaagaagcat gtttttgcta atgctaataa aagaactgct ttcttcgttt tggtcaaatt
     1681 tttacaatta aacggctatc gtttttctgt aacggtagaa gaagcagtaa aaatgtgtgt
     1741 aaccatcgca gtagaagctt taactgatga aaaaatgaca agctactcca aatgggtttc
     1801 tgaacattct gttagagaaa aggtcaaaaa gtaacctagt atgctggatt tgaatgagca
     1861 caagaaaata aatgaacaga caatattaga attctgtaat gcagaaactg atattgtctc
     1921 tttttattga tgaataagaa agtgagaaat tatggaatca aaagttacaa ttatcatgca
     1981 agaaatgtta cctcttttaa ataatgaaca attactagcg ttgagagaga gtttagaaca
     2041 tcatctagta gacggaaaaa agcagcagaa gtattcgaat aataacctgt tgcaactatt
     2101 tattaccgcc aagcaggtag agggctgtag ctcaaaaaca attcgttatt accagaggac
     2161 gattgaaaac ttgtttaatg ctattaaaga gtctgtgaca caactcacaa cagatgattt
     2221 aaggagttat ttagcaaatt accagtctga aaaggattgt agtaaggcaa atttagacaa
     2281 tattaggcgt atattgtctt ctttttttgc ttggcttgag caagaggaat atatcattaa
     2341 aaatcccatt cgacggataa agaaaattaa gactgagcaa aatgtgaagg aaacttatac
     2401 tgatgaacat ttggaaatta tgcgtgataa ctgtgaaaat ttgagagatt tggcaataat
     2461 agacctacta gcatcgacag gtatgcgtgt aggggagctt gtacagttga atcgttcaga
     2521 tattgatttt gaaaacagag agtgtgttgt ctttggtaaa ggaaagaagg agagaccagt
     2581 atattttgat gctcggacga aaattcattt aagaaattat cttaacgaca gaaaagatag
     2641 tcaccctgct ctttttgtaa cgctagttgg aaaagcccag agacttggaa ttgctggtgt
     2701 agagattcgc ttaagaaagt taggagacaa actcggcata caaaaggttc acccacataa
     2761 gttcagaaga actttagcga ctaaggcaat tgataaaggt atgcctatcg aacaagtcca
     2821 aaaactgcta ggtcatagca agattgacac aaccctggcc tatgccatgg tcaatcaaaa
     2881 taatgtcaag cattcacacc aaaaattcat ctcttaaaag caaatcccga tttaacgaga
     2941 tgtttgggga tcctttaaat aataacaaga aatttgcagt aaaaacggga caacagtgtt
     3001 ttaaattttc aagtggaaaa tttcttgata aacatgatag agtttttgaa ggttatcctg
     3061 cctatggtgg aaatggcatt gcttggaaaa gtcgaaaata tttaattgat aatcctacta
     3121 tcatcattgg tcgtgtaggt gcatattgtg gtaatgtaag aactacccac ggtaaggtat
     3181 ggataagtga caatgctata tatataaaag aatttaagaa ttccgatttc aatcttgtat
     3241 ttttattaga attaatgaaa gtaattgatt ttagtaaatt tgctgatttc tcaggtcaac
     3301 caaagataac tcaaaaacca ttagaaaatc agaaatatat cctcccccca ctagccctcc
     3361 aaaatgagtt cgcagacttt gtagccc
//
LOCUS       DAVLHB010000093         3383 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLHB010000093 DAVLHB010000000
VERSION     DAVLHB010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3383
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.093"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            76..258
                     /locus_tag="VXE36_002066"
     CDS             76..258
                     /locus_tag="VXE36_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0780285.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            268..567
                     /locus_tag="VXE36_002067"
                     /pseudo
     CDS             268..567
                     /locus_tag="VXE36_002067"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            631..1609
                     /locus_tag="VXE36_002068"
                     /pseudo
     CDS             631..1609
                     /locus_tag="VXE36_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
     gene            complement(2336..3328)
                     /locus_tag="VXE36_002069"
     CDS             complement(2336..3328)
                     /locus_tag="VXE36_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0780286.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT         1290 a          491 c          479 g         1123 t
ORIGIN      
        1 aaagaaaaaa tcgaaaaatt agctaagaaa tattctgata acttaaacat caaagttcaa
       61 gagagagttc gtgaaatggc aaatgataat aagagccatt atttgatata cagagtttta
      121 ggtatttcat ttgaagaagg agaaaatatc gatttgtatc aaaataaagg tcgtttttta
      181 tacaaatatg ctggttcatt tttagaagaa gctgcagtac tatgctttaa cgaaaaattt
      241 ggtacagaaa atacttaaaa agttaacatt cctaattctg aaagtacaaa acctaagact
      301 tttgaaattg attgtttagt cggaaaaaaa cacgcatacg aaataaaatg gtgggatgca
      361 actacagatg gagaccatat aactaaaaaa cacactagaa taaaagttat tcataacaaa
      421 ggatatatac caattcggtt aatgttctac tatccaaata gaactcaagc tataaaaatt
      481 cagcaaactt tagaaacatt gtataacggt attggaggga aatattatta tggagattct
      541 gcctgggaac atttaagagc agtgaccggt attgatttac ttagtattct aacagatatt
      601 gcaaataaaa aaaacagggg taaaatcaaa atgacagtat taaaaggaga taacttagaa
      661 atattaaaaa ctattgaatc ctcaagtatt gatttaatct atatggaccc tcctttcttt
      721 acacagaaaa cccaaaaatt atctaataac aaaaatatta tgtattcatt cgaagatacg
      781 tggacttcga ttgaggatta caaagaattt ttgtctgtaa gattagaaga atgcaaaaga
      841 gtgctaaaaa atagtggcag tattttcgtt cattgtgata aaattgcaaa tcatcatatt
      901 agattaattt tagataatat ctttggagca gatatgtttc aaagcgaaat tatatggaac
      961 tataaacggt ggtctaattc aaaaaaggga ttattgaaca atcatcaaaa catttacttt
     1021 tattcaaagt caaaagattt taaatttaat acaattttta cagagtattc ttctactaca
     1081 aatatcgacc aaatactagt ggaacgaaaa cgagatggaa actctaaaac tatatataag
     1141 gttgataata atggtaacta tattctagca aaagagaaaa atggagttcc cctttcagat
     1201 gtttggaata taccatttct taatccaaaa gctaaagaaa gagtaggtta tcctacacaa
     1261 aaacctattc tgttattaga acaaattata aagattgcta ctgataaaaa tgatatagtt
     1321 ttagacccgt tctgtggaag tggaactact ttagtagcct ccaagatttt gaatagaaat
     1381 tatatgggga ttgatttatc tgaggaagct atcaatataa ctcagcaacg tctggaaaat
     1441 gttataaaaa caagttcaaa tttattgaat aaaggaatcg aagcatatag aaccaaaact
     1501 gaggaagagg aaaacattct taaattatta caggcaaaaa ttgttcaaag aaataaagga
     1561 attgatggtt ttttacctaa acattttcaa aaaaaaccga tacctataaa aattcaaaaa
     1621 aataatgaat gtctgaatga gagtatctct ttattacaga atgctataaa ctccaaaaaa
     1681 cttgattttg gagtagttat aaaaactcat tcagataatt tattatttga ttttgatacg
     1741 attcctgaaa atataatagt agttgaccat tttgaactta caatcgaaaa atggttaagt
     1801 aaaagtcaac agttactata gtttgcaaat tatttacaga aagaacaaaa atgctctgaa
     1861 acactgattt caaagcattt ttttgttagt ttaaaattac tcccattctt cttttccaaa
     1921 cgtacaatat atccaaaacc attcaaaata ctagattcta ttttttataa tatcactaaa
     1981 tccacctaat tataggacgt tttcagattt ttagtcccgt cccagtccca gtaccggaga
     2041 aatattgttt taatataata tctctttttg tcttctaagc tcttaaaagc aaaagaacaa
     2101 gtaaagagtc aagacaagga taaaaagtcc atattagggc aaataaaaag ctttaagaca
     2161 gatgacaaat ctaagtcaaa taagaaagac catagcaaag gtgcagagag ataaatattg
     2221 gcggtcttcg gactgccttt atttttttat ccatttttca aatcaaattt attcagacta
     2281 tatatgcaca tatacactta aattcatata aaaacatggc ttgtaaaaaa ttactttaat
     2341 cacaataatc gcatttaaaa ttgtgatgtt tgcaagctaa attacggact tcacttggaa
     2401 gttttccctt gtatctttta taatagatag aaaatttgct ggcagatgaa tatccaacag
     2461 attctgctat ctcttttata ggtagttcag tgtttaaaag aagagtttca gctacattca
     2521 ttctttttct ttgagtgtac tctgtaatgc tttgacaata tttttcctta aataaatttt
     2581 ttaatttagt accactcatt ttagatattt tttcaagcgt gccttgattt acattcgttg
     2641 caaaatgatc atctaagaat cttgctacat cttcaagtgc tttatcatca tcaatttcaa
     2701 ttttatattt ttttctattt aagtatgtgt caattactat acttatccat tcatttgcct
     2761 ttgctttaaa gaaaaaatca gcggcaggag cgtccatctt acaatttaat atttccattg
     2821 ccactctttc taaggccttt gtaagtatta tttgattcgg ttgaagcaag gttgaataaa
     2881 aagattctgg attaatgtta atagatgcta aatgtttttc tattagctct tttttaaaac
     2941 caatggaaac agcaagataa caacaattct cgtgtaataa aaaaacaaaa tcatctttta
     3001 tattatcaaa atcaaaagta catagagagt ttgcggtaat agtttgatac ggattaaact
     3061 tttctccgtt tgcactgaca atgtaacttg aataaattga aacatagtct gacatactat
     3121 aagtgctatt ttgaactact tcctctttga tataaaaatc atgtatatcg ataatgaagc
     3181 tgcctccttc ataaaaccaa tataggcctt ctgcataagt tgaattctct tttttccaac
     3241 aaaatgtatg acctgcactt gaatacttct cattgttttt acattcatct actttcatat
     3301 aatcttttac aaaatcataa tatgacataa cacactatcc cttttagaca atattccaat
     3361 tagccttatt aattcaaaac tat
//
LOCUS       DAVLHB010000094         3293 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLHB010000094 DAVLHB010000000
VERSION     DAVLHB010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.094"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..180
                     /locus_tag="VXE36_002070"
     CDS             <1..180
                     /locus_tag="VXE36_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0780287.1"
                     /translation="YENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGV
                     TLITGKNGTGKSTLL"
     gene            complement(546..1856)
                     /locus_tag="VXE36_002071"
     CDS             complement(546..1856)
                     /locus_tag="VXE36_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0780288.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2093..2965
                     /locus_tag="VXE36_002072"
     CDS             2093..2965
                     /locus_tag="VXE36_002072"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0780289.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3096..>3293
                     /locus_tag="VXE36_002073"
     CDS             3096..>3293
                     /locus_tag="VXE36_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0780290.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLK"
BASE COUNT         1033 a          550 c          739 g          971 t
ORIGIN      
        1 tatgaaaaca gaactgtttc ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa
       61 aatatttcgt atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg
      121 agttcaggcg tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag
      181 tagattgaaa ctagaatagt acacatctac ttctaaaata ttgttagaaa ttgatttgac
      241 tatcctgatc tatttgtcct gttcttattt catttcacta tatctcaaat tgagtatgac
      301 gaagtgcgct cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc
      361 atcgataaag actattggga tgaattttta aagttgaact aatcattttt acaggatgag
      421 atttacagca gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc
      481 tcgtttccac ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa
      541 taaatctaac ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt
      601 aagctgatgg ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata
      661 ttgggaagtg agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat
      721 agagcgccaa taacggtggc tgttgtgagt aagtgaatat caatctgagg attttgagca
      781 ctgatgatag caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag
      841 agtgacatca ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggtt
      901 gttgtcatga ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt
      961 aagctcatgc cgcagagcat gataattgta gcccagggaa ccttagctaa aatggcttct
     1021 tgcttcccta atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata
     1081 tcaaatgttt tttgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag
     1141 ggaaaaagcc aaaccaaaac catgctgctg atcatgagca aggtggtttg tctttgaacc
     1201 ttgctgagga gtggtggttg gtcaatagtc aaggatgagt ttgttcttcc cttactatag
     1261 tgactgtaac aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag
     1321 atatgattgc caagtgaaaa agcttgctct tcccatccca tttgcttaaa caggccttga
     1381 aagacaatgc ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg
     1441 gcttgagctc caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga
     1501 cagcaaacgg ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc
     1561 aggtataaaa tcatgtagag ggcgttaggg tgggtgcgtg tgcggtagag aatgtgttga
     1621 gccaaaacat caagagtacc gttagttgtt gcaacgttat aaaagagaga gacgctaaaa
     1681 atggtaaaaa agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg
     1741 agagtggttg cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg
     1801 cggtaaccaa ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa
     1861 ttgtcctttc agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct
     1921 gtttcctatt ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta
     1981 ttgacacttg ttagaattaa aaatgaggta ttcaggcttg tgatttccta tggaagttaa
     2041 tagtaattgc ctctagtgct tacaagtgat attaaaaata gaggacttag tgatgtcaat
     2101 catttcaact gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga
     2161 agatgttcat tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagccaa
     2221 ggtgtcgctt tttgccaagg aagctggtgt tttagcggga ctaaccgttt ttcaaagggt
     2281 ttttacccta tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga
     2341 tcgtttgact agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac
     2401 atgtgaacgc gttgccttga attttttaca acatttatca gggattgctt cgatgacagc
     2461 tgcttatgta gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac
     2521 tcctaattta cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg
     2581 ctttaattta tcagatgcta tcatgctaaa agacaatcac attgcggcag taggtagtgt
     2641 tcaaaaggca attgctcaag cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga
     2701 agtggaaagc cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt
     2761 ggataatatg tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg
     2821 gattgaatgt tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat
     2881 tgattacgtc tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa
     2941 gggtttaacc taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt
     3001 tcctctagaa cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga
     3061 accaaaaata gtacacaatg tggtataatc ttcttatggc atattcaata gattttcgta
     3121 aaaaagttct ctcttattgt gagcgaacag gtagtataac agaagcatca cacgttttcc
     3181 aaatctcacg taataccatt tatggctggt taaagctaaa agagaaaaca ggagagctaa
     3241 accaccaagt aaaaggaaca aaaccaagaa aggttgatag agatagactt aaa
//
LOCUS       DAVLHB010000095         3107 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLHB010000095 DAVLHB010000000
VERSION     DAVLHB010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.095"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            1..435
                     /locus_tag="VXE36_002074"
                     /pseudo
     CDS             1..435
                     /locus_tag="VXE36_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            585..839
                     /gene="blpM"
                     /locus_tag="VXE36_002075"
     CDS             585..839
                     /gene="blpM"
                     /locus_tag="VXE36_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0780291.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            855..1058
                     /gene="blpN"
                     /locus_tag="VXE36_002076"
     CDS             855..1058
                     /gene="blpN"
                     /locus_tag="VXE36_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0780292.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAEIGGIGGAVVCGYLAYTATS"
     gene            1302..1451
                     /gene="blpO"
                     /locus_tag="VXE36_002077"
     CDS             1302..1451
                     /gene="blpO"
                     /locus_tag="VXE36_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0780293.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1555..1674
                     /locus_tag="VXE36_002078"
     CDS             1555..1674
                     /locus_tag="VXE36_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0780294.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1971..2135
                     /locus_tag="VXE36_002079"
     CDS             1971..2135
                     /locus_tag="VXE36_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780295.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            2132..2536
                     /locus_tag="VXE36_002080"
     CDS             2132..2536
                     /locus_tag="VXE36_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0780296.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            2739..>3107
                     /locus_tag="VXE36_002081"
     CDS             2739..>3107
                     /locus_tag="VXE36_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEV0780297.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIATDFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRP"
BASE COUNT          989 a          448 c          643 g         1027 t
ORIGIN      
        1 aaaaaaacaa ttagcgaatg attctggtaa aaagaaattt cacgctatga aggctcaagc
       61 gattgtcaca agtcaaggga gattgtttct ttggatatca ctgtgaacta ttgtcatgat
      121 atgaagttgt tcaaaatgag tcgcagaaat atcggacaag ctggtaaaat cttggctgac
      181 agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg taaatccagc
      241 aaactcaagc cgctaacagt tgaagataaa gcctgtaatc atgcgctatc taaggagaga
      301 agcaaggttg agaatatctt tgccaaagta aaaacgttta aaatgttttc aacaacctat
      361 cgaaatcatc gtaaacgctt tggattacga atgaatttga ttgctggtat tatcaatcat
      421 gaactaggat tctagttttg caggaagtct aatgtaattt ttgcaattca agacgtttcg
      481 atgactattc aagatctgga tgaaaaattt taaaaaacga tgatatacta aacttgtcaa
      541 agttacaaca agacaaaaat taaaaataaa aaagagtatt tgtcatggat acaaaaatta
      601 tggaacaatt tcatgaaatg gatataacta tgttatctag tattgaagga ggcaagaata
      661 attggcaaac taatgtctta gaaggtggtg gtgctgcttt tggtggctgg gggctaggga
      721 cagctatttg tgctgcgagt ggtgttggag caccatttat gggagcatgt ggatacatag
      781 gagctaaatt tggtgtggat ctttgggcag gagtaacagg ggcaacgggt ggattttaat
      841 aaaaggagac ttgtatgaat acttattgta atataaatga aacaatgctg agtgaggttt
      901 atggaggtaa ttccggagga gcagctgtag ttgctgcttt aggttgtgca gcgggtggag
      961 tgaaatatgg gagacttcta ggaccatggg gcgctgaaat aggaggaatt ggaggagcag
     1021 tggtttgtgg atatttagcc tataccgcta catcataaaa atgaaagcta aattttatga
     1081 aggctatatt ctttattatt ctcttcgctt ttcaaaccta tcttatttat ctatccataa
     1141 gtatctccga taaaaaacaa aagactattg aattaacatc attgaattgt tttgtcatat
     1201 tatttctaat ctatgataaa ttaatttttc tctttattgc ctatgttttt ttgataattt
     1261 ttatattaaa cttgttccgt aactgaaaag tgatatacta tatggataca aaaatgatgt
     1321 cacaatttgc agttatggat aatgaaatgc ttgcttgcgt tgaaggtgga gatattgatt
     1381 ggggaagaaa aattagttgt gcagcagggg ttgcatatgg cgcaattgat gggtgtgcaa
     1441 caacggtttg acatttctat tgggaccatt tgctatagga ataggtgtaa ctggtgctgc
     1501 aggtggagct atacttggag gtgtagccta tgcagcaata tgttggtggt aattatggat
     1561 tttaaaagtt ttattattgg tttagtagtt ggtatatttg gtccttatat ggatgactta
     1621 attagaaaaa tattttcaaa atcttccaaa aaggatacgg atagtactct ctaaaaaata
     1681 aatttctccc ctgtatttgc tagcttaatt tacaggggag tttctttaat attgtttcgc
     1741 ctgtcaaaat gatatgtgat agcaggatga aaagtctaca aacaagttgg tatcaataca
     1801 atataaagag gaaagtatgt ttttcatgct tgctttttta atttttacaa ttcaagaggt
     1861 tttgatgacc atttatgatt tgagtgatcc aaggtcaaaa taagtgctat actagcagtg
     1921 taaatgttct tgctcaacta agataaatcg cacatttagg aggaaatctt atgaagaaaa
     1981 aaatactgat tattttcgtt ctgtatctaa tcatgtccat ctttctatat ccgcttaggg
     2041 agagtgcttg gtatcagcta ttttatacca tagcctatgt gattgcagtt atgatctatt
     2101 ttgctatcaa taaaaagaaa ggagaaaaga aatgaaaact tttcttgcta aaaaacggaa
     2161 catcttcctt gcgagattgt tcttaggtca gttgcccttg cttgtttcta cttatctatt
     2221 tctatctcgt cagtttttaa atttttccgt agttttccaa tttcttttag tagttattaa
     2281 cttggcttct attttggtta ctgtttatct cactagggaa atgaggataa gagagtttga
     2341 agatgatgat ttggttagtc ctagaaccaa tcaacttatg ttcatcggct tgacaggttt
     2401 tatgtctatt atttgtttgt atagaggtat cacagcagga gaatcctacc aacaaataat
     2461 cgcttatatt ggcgctgttc tctgcttaat catcatgctt ctgctcatgt ggggcttgaa
     2521 gtattataaa aagtagagct taatgaagta taaaagaaaa gggtaagtgt ttttgcaata
     2581 cttacccttt tataatagat tccctgcgaa acaaaatatg gtatagtata gtagattgaa
     2641 actagaatag tacgcctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     2701 cgatttatcc tgttcttatt tcattttact atagttctat gaattatgaa gcaagtaaac
     2761 aactaactga tgcacgattt aagcgtcttg ttggtgttca gcgcaccact tttgaagaga
     2821 tgttagctgt gttaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta
     2881 aattaagcct agaagacctt cttatggcca ctcttcaata tgtgcgagaa taccgcactt
     2941 atgaagaaat tgcgactgat tttggtattc acgaaagcaa cttaatccgt cggagccaat
     3001 gggttgaagt aactcttgtt caaagtggtg ttacgatttc aagaactcct ctcagttctg
     3061 aggacacggt aatgattgat gcgacggaag taaaaatcaa tcgccct
//
LOCUS       DAVLHB010000096         3091 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLHB010000096 DAVLHB010000000
VERSION     DAVLHB010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.096"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(88..1044)
                     /locus_tag="VXE36_002082"
     CDS             complement(88..1044)
                     /locus_tag="VXE36_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0780298.1"
                     /translation="MEDLISIVVPVYNVEKYLKKSIESILNQTYQNIEILLVDDGSTD
                     SSGKICESFSKVDPRIRVFHKENGGLSDARNFGIEQMKGQYVAFIDSDDYISKDYVWK
                     LYSSIKNNDSEVSICSFLLVDEKGEKIKDELLDSGKICLTGQQILEKVLTADGYRYVV
                     AWNKLYRSTLFEKLKFKKGMLYEDEFLNYPLFWDCKRVSIVEEPLYLYVQRKGSIVQS
                     NMTLEKIKMKDEMHTSRIEFYSEKGHSFLHEKACQQYCNWIVTATTNHSKILNPNFSK
                     YLQRQFRKFAKYTRNNDIRLIVQNILGFIDIRLAAYVKSKVM"
     gene            complement(1052..2077)
                     /locus_tag="VXE36_002083"
     CDS             complement(1052..2077)
                     /locus_tag="VXE36_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0780299.1"
                     /translation="MIEVSIIIPIYNAEKTIKNCVDSALKQNLESLEVILVNDGSNDS
                     TAEILNQYDRNSRVKIFHQLNKGVSTARNKGLSHASGEYVFFLDSDDILDDGMLSKMY
                     QFVKNNKVDLLSCWHKEPATTQYGGNENKSTSFIARTREEIGAHFVDIFPRSACAKLF
                     FRKIIEENNITFSTEMSLGEDMSFVYQYLMVSKSIGVIDGVYYNIQNVNPQSLSKRYV
                     QNIENSLIIQNQLWNQLLEVYPKIEENYYKQHMDFRFYLANLYVNNLFKFDSPYSSKE
                     KLDQIAQQLKKYRLFLDEKVSKEKMPKNINEMIVFYLLKLKIPVLIYSFYSFKEWWKR
                     RKIKNEG"
     gene            complement(2074..>3091)
                     /locus_tag="VXE36_002084"
     CDS             complement(2074..>3091)
                     /locus_tag="VXE36_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HEV0780300.1"
                     /translation="APSFYIVLWVMIYSISIIWNFLISGLPIQVFFSDLSKAFNWILA
                     VFFYNYYLKNPINVDKIKKYMFYNFAILVIIVALFYVQRGANVVLFGRSLLGWDGFVS
                     ATSYGVRYAGFLEYSTLNGQLILFLLPLIRLFKLSFFTQVTILAFLLQVLVLSKSRIA
                     IIALIIYIVFVVMVQITSINKRMIVAFYPTIPLILLYNWEKIKHIFFQMFNSRTGSNV
                     TRFIVYEESLKAINGLGILLGAGIRTQSTVGILLGSHSMYISFIYRTGILGSIIIVIL
                     FYYLFSKFLKSAPSGKLISIGYILALLVFWLFEELDPHYWCLILFFSTISIFINNRKE
                     EIVG"
BASE COUNT         1101 a          559 c          344 g         1087 t
ORIGIN      
        1 tctatgaatt ttatccttca atttactata aaaagaatga tttttaatag aatctaaaat
       61 tttttctatc attatgtttc ctatactcta cattactttt gattttacat aagctgctaa
      121 acgaatatct ataaatccta gaatgttctg cacaattagt ctaatatcat tgtttcgtgt
      181 atatttagcg aactttctaa actgtcgttg taaatacttt gaaaaattag gatttaaaat
      241 cttactatga ttggtagtcg ctgtaacaat ccaattgcag tactgttgac acgctttttc
      301 gtgcaaaaaa gaatgcccct tttctgaata aaactcaatg cgtgaagtat gcatctcatc
      361 cttcatcttt attttttcta aagtcatatt actttgtaca atgcttcctt ttcgttgaac
      421 gtataaatat aacggctcct ctacaattga taccctttta cagtcccaaa atagaggata
      481 gttaagaaat tcatcctcat acaacattcc ttttttaaat tttaattttt caaataaagt
      541 tgaccgataa agcttattcc aagcaacaac atagcgatag ccgtcggctg ttaatacttt
      601 ttctaatatt tgttgaccag tcaagcatat ttttcccgaa tctaatagct catcttttat
      661 tttttcccct ttttcatcga ctaataaaaa agaacaaatc gacacctcgg aatcattatt
      721 ttttatagaa gaatacaact tccagacata atccttagat atgtagtcat cgctatcaat
      781 aaacgctaca tattgacctt tcatttgctc aattccaaaa ttccgagcat ctgataaacc
      841 accattttct ttatgaaata ctcttatcct aggatcaact ttactaaatg attcacaaat
      901 tttcccacta ctatctgtgc ttccgtcatc aaccaataaa atctcgatat tttgataagt
      961 ctgattcaaa atactttcta ttgatttttt taaatatttt tccacgttat agactggaac
     1021 aacaatgctt atcaaatctt ccataactta tttatccttc atttttaatt tttcttctct
     1081 tccaccactc tttaaacgaa taaaaagaat aaatcaacac tggaattttc aattttagta
     1141 aataaaaaac aatcatctca tttatatttt taggcatctt ttctttgctg actttttcat
     1201 ctaaaaataa tctatacttt tttaattgtt gagcaatttg gtctagtttt tcttttgatg
     1261 aatacggaga atcaaattta aataaattat ttacatacaa gttagcaagg taaaatctaa
     1321 aatccatatg ttgcttatag tagttctcct caattttagg ataaacttcc aacagttgat
     1381 tccataactg gttctgaatt attagggaat tttcaatatt ctgcacatag cgcttagata
     1441 acgactgtgg atttacattt tgaatattat aatacacccc gtcaataact ccaatacttt
     1501 tagaaaccat taagtattga tacacaaatg acatatcttc acctagtgac atctcagtcg
     1561 aaaaagtaat attattttct tcaattattt tgcgaaaaaa caatttggca caagcacttc
     1621 tcggaaagat atcaacaaaa tgagcaccta tttcttctct tgtacgtgca ataaatgaag
     1681 ttgacttatt ctcatttcca ccgtattgag ttgtagcagg ttctttatgc caacaagata
     1741 agagatcaac tttattattt tttacaaatt ggtacatttt agaaagcata ccatcatcta
     1801 aaatatcatc tgaatctaga aaaaatacat actctccact agcatgagat aaccccttat
     1861 ttctagcagt agacacccct ttattaagct gatgaaaaat cttaaccctt gaattcctgt
     1921 cgtactggtt caaaatttct gctgtagaat cgttagaccc atcattcacc aaaatcactt
     1981 caagagattc taaattttgc tttaaggcac tatcaacaca atttttaata gttttttcag
     2041 cattgtatat tggaattatg attgatactt ctatcatcca actatttcct cttttctatt
     2101 gtttatgaaa atacttattg ttgaaaaaaa taaaattaaa caccaataat gtggatctaa
     2161 ttcttcaaaa agccaaaaca ccaataaagc taaaatatag cctatactga ttaactttcc
     2221 agatggggca ctttttaaaa atttagaaaa caaataatag aacagtatta ctattattat
     2281 acttcctaaa atccctgtcc tataaataaa actaatatac attgaatgtg atcctaataa
     2341 tatacctact gtagattgtg ttctgattcc tgctccaagt aaaattccca gcccattaat
     2401 agctttaaga gattcttcgt acactataaa acgtgtcaca ttactacctg ttcttgaatt
     2461 aaacatttga aaaaagatat gtttaatttt ttcccaatta taaagcaata taagaggtat
     2521 agttggataa aacgctacaa tcatccgctt attaattgaa gtaatctgaa ccattactac
     2581 aaatactatg tatataatca gagcaataat agctattcta gatttactca atactaaaac
     2641 ctgtagcaaa aaagcaagaa tagttacttg tgtaaaaaaa ctaagtttaa ataacctaat
     2701 taacggtaac aaaaaaagaa tcaactgccc atttaatgtt gaatattcta aaaatcctgc
     2761 atatcttact ccgtaactgg tagctgatac gaatccgtcc caacctaata agcttcttcc
     2821 aaacaatact acattagcgc ctctttgaac atagaataaa gcaacaataa taactaatat
     2881 agcgaaatta taaaacatat atttctttat cttgtcaacg ttaatgggat ttttcaaata
     2941 ataattataa aaaaatactg ctaatatcca attgaatgcc ttactcaaat ctgaaaaaaa
     3001 cacttgaata ggtaagccac taattaaaaa attccaaatt attgatatag aatatatcat
     3061 gacccataga actatataaa aagacggtgc a
//
LOCUS       DAVLHB010000097         2912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLHB010000097 DAVLHB010000000
VERSION     DAVLHB010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.097"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            19..906
                     /locus_tag="VXE36_002085"
     CDS             19..906
                     /locus_tag="VXE36_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0780301.1"
                     /translation="MIRAVKSCLHQSYKNIEVIIIDDNYSNVNLRNKIIHQFGYTNHR
                     IKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDEYMSDRILKLMACFKKSRMKNLA
                     LVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEVLELINGFEKID
                     SHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGITGVTQKTINADEEYYNYCRKY
                     FNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKVIKKAREEKIFNEFLFLKYMLLY
                     CFGFFYCIYDNYVQLKFRK"
     gene            916..2532
                     /locus_tag="VXE36_002086"
     CDS             916..2532
                     /locus_tag="VXE36_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780302.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT         1057 a          331 c          527 g          997 t
ORIGIN      
        1 cataataggt atgaatctct gattagagct gtgaaaagtt gtttacatca aagttataaa
       61 aatatcgaag ttataattat tgatgataat tatagtaatg taaatttaag aaataaaatt
      121 atccatcaat ttggctatac caatcataga attaagttaa ttttaagtaa tgaagattta
      181 ggtgcaacta atgccagaaa cataggtatc aaaaattcta gaggtaagta tatatcattt
      241 ttagacgatg atgatgaata tatgtcagat cgaattttaa agttgatggc ttgttttaaa
      301 aagagtagaa tgaagaattt agctttagtt tatagttatg gaataataat ttatccaaat
      361 ggtacacgag aagaggagaa gaccgatttt gttggaaatc ccttgtttgt tcaaatggtt
      421 cacaatatag caggtacgtc attttggttg tgtaaaaaag aggtgctaga attaattaat
      481 ggttttgaga aaatagattc acatcaggac ggtgttgttt tattaaaact acttgctcaa
      541 ggataccaaa ttgatatagt gcgagaattc ttggtgaatt actacgctca cagtaaagaa
      601 aacggtatca ctggagtgac acaaaaaaca attaatgcag atgaagaata ttataattac
      661 tgtaggaaat attttaattt attgagtttc aacgagagaa tattggttac aaagaaatat
      721 tattctttaa acataaagcg gttactatta ataggagaca aatgcaaggc tttaaaagta
      781 atcaagaagg caagagaaga aaaaattttt aacgaatttc tttttttgaa atacatgtta
      841 ttatattgtt ttggtttttt ctattgtata tatgacaact atgttcaatt aaaatttaga
      901 aagtgagaaa ctattgtgta tactattata aaatcaaata taaaaaaatt tagtttatta
      961 acgatattta ttgttgctgg tcaattattg ctaatttatg cagcaactat taatgctctg
     1021 gtgttgaatg aattaattgc gatgaattta gagcggtttt tgaaattgtc aatctaccaa
     1081 atgattgtct ggtgtgggat aatattcctt gactgggtag tgaaaaatta tcaggttgaa
     1141 gtgatccaag agtttaatct agagattcga aatagagttg ccacagacat ctctaactct
     1201 acctatcaag aatttcatag taaatcatca ggaacatatc tttcgtggct aaataatgat
     1261 gttcagactt taaatgatca ggcttttaaa caactttttt tagtaataaa aggaatttct
     1321 ggtactatat ttgcagttgt gactcttaat cactatcatt ggtcattgac tgtagccacc
     1381 ttgttttcat taatgattat gctacttgta ccaaaaatct ttgcatcgaa aatgcgagaa
     1441 gttagtctaa atttaactaa ccaaaatgaa gcttttttaa aatctagtga gactatattg
     1501 aatggatttg atgtgttagc gtccttgaat cttttatatg tattgcctaa gaaaattaaa
     1561 gaagcaggaa ttttattaaa gatggttata caaagaaaga caactgtaga aacgttagca
     1621 ggcgctatta gcttctttct caatattttt tttcagatat ctctcgtttt tttaacaggc
     1681 tatcttgcaa taaaaggaat agtgaaaatt ggtactattg aagcaatagg agcactaaca
     1741 ggtgttattt ttacagcgct aggtgaatta ggaggtcaat tatcctctat tattggtacg
     1801 aagcctattt ttttaaaatt gtattcaatt aatccaattg agtcaaataa aatgaatgat
     1861 atcgaaccaa atgaggtgaa tagagatttt ccgttatatg aagcaaaaaa tatttgctat
     1921 aagtatggag ataaagaaat attaaaaaac ttaaattttt gttttcaacg taatgaaaag
     1981 tatttaattt taggtgaaag tggaagcggg aaatctacat tattaaaatt attgaatggc
     2041 tttttgagag attatagtgg agaattgcga ttctgcgggg atgatataaa aaaaacctcc
     2101 tatttaaata tggtttcgaa tgttctatat gtagatcaaa aagcttattt gtttgaaggt
     2161 acgattagag ataatatttt attggaagaa aattatactg atgaagaaat actacagtct
     2221 ttagagcaag ttggtttgag tgtaaaagat tttcctaata acattttaga ttattatgtt
     2281 ggtgatgatg ggagattact gtcaggaggg cagaaacaaa aaattacttt agctagaggg
     2341 ctaattagaa ataagaaaat agtattaatt gacgagggaa cttctgctat cgataggaga
     2401 acttcgttag cgattgaacg taagatatta gatagagagg atttgactgt cattattgtt
     2461 acccatgctc cgcatccgga acttaaacaa tattttacta agatatatca atttccaaag
     2521 gattttattt aagaatatag gggagggaaa catgagattc tattgtgaag cttatgaggt
     2581 aattactgaa gagaaaaaag tatcattttt ttatgtagat gagaaaccct taaggtatct
     2641 gttatttgac tatatatttc tactagttct agctaaaaaa aaatatccca atcttatgaa
     2701 ctgcacccca aaagttagat ttattctgtc taacttttgg ggtgcagttc attttgcata
     2761 gttttggcat tcatcctaga tatccatata aaatgtctga gattgttgaa atgtctaaaa
     2821 aaatatcaga tctaaacgat aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc
     2881 aagatagtgt tcttgataac ataaacccca at
//
LOCUS       DAVLHB010000098         2709 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLHB010000098 DAVLHB010000000
VERSION     DAVLHB010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.098"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..2116)
                     /locus_tag="VXE36_002087"
     CDS             complement(<1..2116)
                     /locus_tag="VXE36_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEV0780303.1"
                     /translation="MFKVLRGGVDTTQVMTETVKDKVSHSITGLDILKGIAAAGAVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPVINASLNIA
                     KSETKVYTGKGVDSVYNVPIYYRLTVTNDGLKLTFTYTVTYVDPITKTLGNLSRMSRG
                     YSIYNTGTIYQTMLTLGKGLRTPSSVKNYITDKNGKQVQYYNMSTMTTQGSGYTWGNG
                     AQMNGWQAKQGYGLTSSWTVSITGTDTSFTFTPYAAKTDKIRTNYFNGGGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASASASTSASASASTSASASASISASASASTSASASASTSASVSASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASISASESA
                     STSASVSASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASAST
                     SASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSA
                     SESASTSASTSASTSASASASTS"
     gene            complement(2114..2227)
                     /locus_tag="VXE36_002088"
                     /pseudo
     CDS             complement(2114..2227)
                     /locus_tag="VXE36_002088"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2473..>2709)
                     /locus_tag="VXE36_002089"
     CDS             complement(2473..>2709)
                     /locus_tag="VXE36_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0780304.1"
                     /translation="PEKVAEFLDILDNLKDLPVLYIDETGINRYLYRPYAGAPRGEKV
                     YDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
BASE COUNT          685 a          574 c          618 g          832 t
ORIGIN      
        1 cactcgttga tgctgaagct gacgcactgg tgcttgctga tgtcgacgca ctcgttgagg
       61 ccgattcaga cgctgaggtg cttgctgaag ctgatgcact tgttgaggct gaggctgaag
      121 cgcttgtcga tgctgaggct gacgcactcg ttgatgctga agctgaggcg cttgtgcttg
      181 ctgaagccga agcactggtg cttgctgaag ccgaggcact tgtcgatgct gaggctgagg
      241 cgctcgttga tgctgaagct gaagcactcg ttgatgctga agctgacgca ctggtgcttg
      301 ctgaggctga ggcactggtt gatgctgaag ctgacgcact ggtgcttgct gaagccgatg
      361 cacttgttga tgcggaagct gacgcactgg ttgacgctga gactgaagca ctcgttgatg
      421 ccgattcaga cgctgagata cttgctgaag ctgaggcact ggttgatgct gaagccgaag
      481 cactcgttga tgctgaggct gaagcgcttg tcgatgctga agccgaagca cttgttgacg
      541 ctgatgctga ggcgctagta cttgctgagg ctgatgcgct tgtcgatgct gaggccgagg
      601 cactggttga tgctgaaact gaggcgcttg tgcttgctga agccgacgca ctggtgcttg
      661 ctgaagccga tgcacttatt gatgctgaag ctgaggcgct tgttgatgct gaggctgagg
      721 cactagtact tgctgaagcc gatgcacttg ttgacgctga tgctgaggcg cttgtgcttg
      781 ctgaggctga cgcacttgtc gacgctgaag ccgaagcact ggtgcttgct gaagctgaag
      841 cactcgttga tgccgattca gaagcactgg tacttgctga ggccgaggcg ctttgactag
      901 cacttactga tagtgactta gactgtgaaa gtgactgact ggtcgtgcta gattcaacta
      961 cctttcctcc accattgaag tagttagttc taattttatc tgttttagca gcgtaagggg
     1021 taaatgtaaa ggatgtatcc gttccagtaa ttgatacagt ccaagatgat gttaatccat
     1081 atccttgctt agcctgccaa ccattcattt gggcaccatt tccccaagta tacccactac
     1141 cctgcgtcgt cattgtagac atattatagt attgaacctg tttaccattt ttgtcagtaa
     1201 tgtagttctt tacacttgaa ggtgttctca atccctttcc taacgttaac atcgtttgat
     1261 aaattgttcc tgtattatag atagaatatc cacgagacat tcttgaaaga tttccaagag
     1321 tctttgtgat aggatctaca tacgtaaccg tataggtaaa ggtcagtttt aagccatcat
     1381 ttgtcactgt caatcgatag taaattggaa cattatatac cgaatctaca cctttacctg
     1441 tataaacttt tgtctcactt ttagcaatgt ttagacttgc attaattaca ggggcgccat
     1501 ttacaatcgt attgccagaa aaaacagcag cttttataga agccagcaat tgctcgatgg
     1561 aatccactga acgcttgcgt cgcttagcat aagattggag attgacattt gtaactgatg
     1621 ctgcataatc actagctggt ttcttacgat cttcttcgac cttcttagca gttgcttctg
     1681 tagcggcagc tgtttgtgat cctaccacag tagatgatgc agagatactt gtcgaagccg
     1741 atgtacttgc tgattctgat gcacttgtac tcgctgaggt cgaagcgctg gttgaggctg
     1801 actcagatgc agatgtactt gccgactctg aagctgacaa actagttgaa ctcgctgaat
     1861 tacttgtaga tatcgtacct agaactactg taccatttgt tgccaaagca tccgttttct
     1921 ctacagtttt ttcaagtact gccgactcat ttgtaaatac cttcgtttga gttgcaacgg
     1981 ttccacttat gacagctccc gcagcagcta ttcccttgag gatatcaagc ccagtaattg
     2041 aatgacttac tttatctttt accgtttcgg tcatgacctg agtagtatca acaccacctc
     2101 gcaagacctt aaacaagcca aaaagagaag tcgaggcccg tagccaatgc ttccctgatt
     2161 tgattaattt gaaccgagtt actcggtctg tttctctata ttcacccttc tgacgtctaa
     2221 aaaatatttt gaaatttcct ttcgagtatt attttcatgt atggatataa ataaattacc
     2281 atactataat tatagaatag ggaacccaaa atagcaagaa acttgaggta tttttgctaa
     2341 aaaaaaaaag cattttacta ttttgtatat atatatatat attataagat aagtttttta
     2401 taaagacacg caaatgtgta taaatcagct aatttttggt ttacattcct atttttatgc
     2461 ataattattc tttcattctc taatttgtga atcaatatat ctgattagaa aactaccatt
     2521 gagtttttgc tccacctcat tagtccgctc aaaacgccgt ccgctaatct tgtcatagac
     2581 tttctcccct ctaggagctc ctgcataagg acgatagagg tagcggttga ttcccgtttc
     2641 gtcaatatat aggactggta aatcttttag gttatccaaa atatcaagaa actcagcaac
     2701 tttctctgg
//
LOCUS       DAVLHB010000099         2585 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLHB010000099 DAVLHB010000000
VERSION     DAVLHB010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2585
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.099"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            211..1434
                     /gene="dcm"
                     /locus_tag="VXE36_002090"
     CDS             211..1434
                     /gene="dcm"
                     /locus_tag="VXE36_002090"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEV0780305.1"
                     /translation="MIWVLDLFAGIGGFRMGMEAQGHECLGFCEIDKFARKSYKSIFQ
                     TEGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIA
                     RAAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPKNR
                     ERVFIIGHSRKKGTRLLFPFRREGQATNSETLKALGNLNPSRSGMSGKVYYSEGLAPT
                     LVRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRYGIVVVGDLPTSF
                     KETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINL
                     ERPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGVLIDGQFYRLRIR
                     RITPKECFRLHGFPD"
     gene            1462..1572
                     /locus_tag="VXE36_002091"
     CDS             1462..1572
                     /locus_tag="VXE36_002091"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0780306.1"
                     /translation="MNSQLYKQVGNSVTVPVIAAIAKKLKEIEEKDKSIK"
     gene            1556..2005
                     /locus_tag="VXE36_002092"
                     /pseudo
     CDS             1556..2005
                     /locus_tag="VXE36_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1998..2378
                     /locus_tag="VXE36_002093"
     CDS             1998..2378
                     /locus_tag="VXE36_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0780307.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIGLPFVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            2391..>2585
                     /locus_tag="VXE36_002094"
     CDS             2391..>2585
                     /locus_tag="VXE36_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0780308.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQ"
BASE COUNT          884 a          391 c          578 g          732 t
ORIGIN      
        1 gaagaaaagc gtcgttaatg atgcattaaa gaacagtcga gatgaaaaaa tcgtgtgacg
       61 aaccaaggga ggagtctgcc cttttgagga aatctagcga ggaaaaacga tactggaaca
      121 gcagaaagta aaactgacct catgaggagg aagaaagtgg ctcatgaggt caggggtttt
      181 gtaagttaca tctagttgag agaggtatga atgatttggg ttttagattt atttgctggg
      241 ataggaggct ttaggatggg aatggaagct caagggcatg agtgcttggg attttgtgag
      301 attgataaat ttgctaggaa atcttataag tccatttttc aaacggaagg agaaatagaa
      361 tttcatgaca tacgagatgt ttcagatgac gaatttaaaa aacttagagg gaaagtcgat
      421 gtcatctgtg ggggattccc ttgtcaagca ttttcaatcg caggaagacg attgggattt
      481 gaagatacta gaggaacttt gttctttgaa attgctcggg cggccaaaca aatccaacca
      541 cgttttcttt ttcttgaaaa tgttaaaggc ctactcaatc acgataaggg acggacgttc
      601 accacaatac ttaccacact tgatgagttg gggtttgatg ttgagtggca ggtgcttaac
      661 agtaaggatt ttggcgttcc caaaaacaga gagagggtgt ttattatcgg acattctaga
      721 aagaaaggta ccagactctt atttcctttc agacgagaag gtcaagcaac taactctgag
      781 actttgaaag cactaggaaa tttgaatcca tcaagaagtg gaatgagcgg taaagtctat
      841 tattcagaag gtcttgcgcc aaccttagtt cgtggtaaag gagaaggatt taaagttgcg
      901 attccttgta tgacaccaga tagattagac aagagacaaa atgggagacg ctttaaggaa
      961 aatcaagagc cgatgtttac tttaaatact caggatcgtt atggcattgt cgttgttgga
     1021 gatttaccga ctagctttaa ggagacaggt cgtgtctatg gaagtgaggg cttatctcca
     1081 acactgacta cgatgcaagg aggagataaa atccccaaaa tactaattcc agaaccaatc
     1141 caatttctaa aagtacggga agcaacgaaa aaaggatatg ctcaagcaga gattggggat
     1201 tcaatcaatt tagaaagacc aagttctcag tatcgtcgtg gtagagttgg aaaaggtata
     1261 gctaatacgt taacaactag tggtcaaatg ggagtagtag tggctagcta tgaaggagaa
     1321 gataaacaag tttaccaagt agctggtgtt ttaatagatg gacaatttta ccgtttgaga
     1381 atacgacgaa tcactcctaa agagtgtttt cgattgcatg gctttcctga ttaggctttt
     1441 gaagctgcta gaaaagtctc tattaatagt cagctctata aacaagttgg taatagtgta
     1501 accgttcctg tgattgccgc aatcgcaaag aaattaaaag aaatagagga aaaagataaa
     1561 agcattaaat aaagaatcaa tactagattg tgatgaatta gaaacagaat tacatgatgc
     1621 agaaatcaaa cagctggatg aacaaatatt tttgatgccc aattatccat gtgagtttga
     1681 ggtaacattt ttagatgatt accataaaaa acataattac ccactatttt atgaatccta
     1741 tcttcaaaac gttatggaat tccttgaaag tcaggatata aagaacggag ttaatgcctt
     1801 tgtagatgat aatcagaatc ttgtttttgt tttatattga caagactatc gagccgaggg
     1861 aaaagagggg atacttacaa cccaagtaac tgtaaaagct tatgatgaag acaagaaatc
     1921 gattaacttc tcaaagttgt tagattcctt aatcgtctca gaatatcaaa tggaagcaaa
     1981 tttgttggag gtctcccatg attgatctct atctaagtaa aaatagccaa agaaatcaac
     2041 ttcttttaga cttcttccaa aactatggca ttgaggtatc ttgtcattca gtttctgaaa
     2101 tgacaaagga caaattaatt gagatgatga gctattcttc agattgtttt gagtttttat
     2161 ctcccaattt attacgattt aagaaccgtg acaatctaag attaacggat ttcgttgaga
     2221 taattttaaa aaatcctgaa ctaaccatcg gacttccttt tgtggtttca aataagcggg
     2281 tttatccaag tctgaatttg gaagaggcta gagctctatt gccaagagat acgaaacaat
     2341 tgatttacat ggcacaaaca cattatttat ctaactaaag gagaagtaat atggctgaac
     2401 gattttggga gaacttgtcc attattttgg ctgaaagaaa tatcagctgg attgagttaa
     2461 ccagaaaaat gtttgcggga gagtttcact atccaagtga attgaatcgt ttatatcaaa
     2521 agattcgcca ctacaagatg gaacaacgaa tgcctcaaag tccatgggta gaaaggattg
     2581 tgcag
//
LOCUS       DAVLHB010000100         2495 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLHB010000100 DAVLHB010000000
VERSION     DAVLHB010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.100"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            355..975
                     /locus_tag="VXE36_002095"
     CDS             355..975
                     /locus_tag="VXE36_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0780309.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            990..1730
                     /locus_tag="VXE36_002096"
     CDS             990..1730
                     /locus_tag="VXE36_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0780310.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            1733..>2495
                     /locus_tag="VXE36_002097"
     CDS             1733..>2495
                     /locus_tag="VXE36_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0780311.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSI"
BASE COUNT          860 a          316 c          453 g          866 t
ORIGIN      
        1 gataaaaagt tggataaact agaagattct acttttaatt tgaaacgatc agaggttctt
       61 tcaaaattgg ttgcagtact aatttcaggt ttttgctttc tagttccctt ggttgtagga
      121 tgttattttg taatttatca taaaagcctt tcttttagtg aactgatagg tattttctta
      181 gcaaacgata aagttttagg gccgatacaa tcaattgcct attcattaaa taagataaat
      241 acaaccaaag atttaaggaa accgttttta aaatacttaa gtggagagaa gaattttata
      301 gacgctgaac atgataataa cggactgtat acttcatcaa tagatgagat acacatgaaa
      361 gatgttgtat attctattac accagaaaat aaattaagta ttgacttctc atttaagtca
      421 ccatttaggg tattattaac aggaacttct ggtagtggga aaacaacgat tttaaattta
      481 attaatggtt ctttaaagcc acaaaaaggt tatgtaaatt tgttatcaca tgggaaaaag
      541 agttcagatt caataccaac agttgatcag acaccatata tttttgacac tactattcgt
      601 gagaacgtaa ctttatttca aaatgaatat ttttcagatg atcagataat tgaggtgtta
      661 aaaaaggtaa atctatatga agaattagaa aagatagata tactaaatta tcaatgtggt
      721 gaaaatggta gtaatttgtc tggaggtcaa aaacaaaaaa tagctttagc tagagctctg
      781 attagaaata ataaagtgta cttatttgac gaaatatcag ctaatttaga taatgataat
      841 tcaaattcca tacatgatat tctgttcaat ttaggtattt catttattga agtttcacat
      901 cattatgact taaatgacaa gagatacact gatatatata aattggaaaa tggaacactt
      961 ttcaaaatta agtgattgga ggcaagaata tggataaaga ttatatatta aaagtgaaag
     1021 ggctgtatca tcaattttta ctaggaaata ataaaacgtt gcaagtgctg aaaaatgttt
     1081 ctctttctgc ttcgagagga gaatttataa gtattctagg aattagtggt tctggaaagt
     1141 caactttatt aaaatgtatt tctagtttgc ttgaaccaac aagtggggaa gtaattttaa
     1201 atggaatcaa cccctataaa atcagaaatg caaaattgtc aagtataaga cgtaacgaag
     1261 tatcttttat atttcaagca tacaatttaa taccttccct gccggtaata gaaaatatag
     1321 cacttccttt gcgattatca caaaaaaaat taactattaa aaatgtagaa aacttactca
     1381 aaagaatgaa gtttaatgct ggcttaaacg attttgttgg aactctgtct ggtggagaac
     1441 aacagaaggt tgctatagct agagcggtta ttgctgatag tgatataata tttgctgatg
     1501 agccaactgg ggctttagac agcgtttctc gtgaagtaat ttttgaatta ttgagagagt
     1561 tagtaggggc gggtaagtgt gtaattatgg taacgcacga tatagaattg gcctcgaaaa
     1621 ctgatcgtgc attaatattg aaagatggaa aaattttcaa agaacttcat agacctagcg
     1681 gggaagagtt gtataaaatc ttagaggtac aatcaactac ggaggaatag agatgctcag
     1741 attagtttac tatcaatttt tacataataa gaaacaatgg ttaggcgttt caccagtaat
     1801 ttttgtttcg agtttagtta tgggattggc tgttaatggg gtaattaatg ttgagaataa
     1861 ttcgcaagta tttgtcggac ttccagatcc taaaccaatt tttatgtttc cgatagtatt
     1921 cggaggagta acattattct ttgtgctctc taacataata aatatgttgg ttgaaatttt
     1981 tagagatgat tacgaacttc tggaggtgtt gggagcaagt cgccttcaac tatcatttct
     2041 tgtgggggga cagattttta tcatttcctc gattattagt tttattgcat atctatgctc
     2101 tatatttgtt acgtcaaatt attattattt tttacaatac tttttcgggg aaaatatatt
     2161 acctgatatc caatttcaaa cgagtgctgt tggatgtatc attacagtag tgttgatttc
     2221 atttttagcc tttctaagtg gttgctttta tacgttcaag aagattagaa ataggaagag
     2281 ttctaaaata aggcatgttc tttcaatagt aaaaagaata ctgctattgg ctggttttag
     2341 tgttatctgg ttgctttctt tgcaacaaat tttccaagat agcacaattt tagcgaaggc
     2401 ccagataata ttcaatattg taatcttaga tattgtgatt atttatcaat tatctccttt
     2461 tatacagtca tgttttatca aactactttc tataa
//
LOCUS       DAVLHB010000101         2036 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLHB010000101 DAVLHB010000000
VERSION     DAVLHB010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2036
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.101"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            587..1387
                     /locus_tag="VXE36_002098"
     CDS             587..1387
                     /locus_tag="VXE36_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780312.1"
                     /translation="MKYCDENNIKPWEWDFKNHSLSPLPNDSITAFLKYRQLPENEGI
                     DCDKAAFFLYKCLGWQESQDSTIRGETMNSFITIFKEAIGNSSNFDEESTKLGITKKK
                     IPISVLCEHQNYLKFETIQNNLENFKLFARTTHTIGNFTVFPNWMNCGRGLRLGDYWD
                     ITLISLQEFLNILSPEAWENFIKMYHLQPYVNSDYSVELFWDNHNNNAIRPTKEENFQ
                     IFLKKVNERIEERGKFIIKQICDQLDQKDFNFYKEIENMDKIKFSNEF"
     gene            1400..1870
                     /locus_tag="VXE36_002099"
     CDS             1400..1870
                     /locus_tag="VXE36_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780313.1"
                     /translation="MVRVYKSVRLAYEAKVWIDELIQNKERKIKELSQNNFLSTLEQT
                     LLSNHYDELNGVSFNIVLKASIGSVIEESYRNTKHYSIDEWQKLRQEMEKDIKNVNPS
                     LETSVTPRLYLDENVLNGLDEFRYHLMKEDGATRLPRLSYIIKLVVYSYWKTQQ"
BASE COUNT          804 a          269 c          310 g          653 t
ORIGIN      
        1 ccattttaat ttttataact ggaattagac aagtaggttc atacggaaaa ggaagtggga
       61 tagggggatt agagcacaaa ttccaaagta gaaatatgat cgaaatgtac ataggagaat
      121 acattttaaa gcaaggaata gcaatacttg ataaatattc tcataaaaac tataagctaa
      181 caccagatga atgggacgac gaaactgata aaatctttaa ttattataac attaataatt
      241 aaagatatag atttcattca ctaatagtac aactgatgaa aagatttaaa attataacaa
      301 cgcataatat ttcggtaaaa cttgatattg tgcgttttat catggacatt tttctactca
      361 aattgagatt tatgtttttc cacatcagtc tttaattaat tttttaatac ttaacttaac
      421 aagtgggaaa caacgaaaca atagacagct taaaaaattg gagttttttt aaaaaaactc
      481 ttgcaattct tttttaaagt gttataataa tttgtataag ttgtcctaat acaacaatca
      541 aaaaaacagg aggattctta tgaaacatca agaagttatt gattggttga aatattgtga
      601 tgaaaataat atcaaaccat gggaatggga ttttaaaaac cactcacttt ctccactacc
      661 caatgatagt attactgctt ttttaaaata cagacagctc cctgaaaatg agggtataga
      721 ttgtgataaa gctgcattct ttctatataa atgtttggga tggcaagaat cacaagatag
      781 taccattaga ggagaaacaa tgaactcctt tattaccatc tttaaggagg ccattggaaa
      841 tagttcaaat tttgatgaag agtcaacaaa attaggcata acaaagaaga aaatcccaat
      901 ttctgttctt tgtgaacatc agaattattt aaaatttgaa actattcaaa ataatttaga
      961 gaactttaaa ttatttgcaa gaacaactca tacaatcgga aattttacag tatttcctaa
     1021 ttggatgaat tgtggtagag gtcttagact aggtgattac tgggatatca ctttaatatc
     1081 acttcaagaa tttttaaaca ttctatctcc tgaagcatgg gaaaacttca taaaaatgta
     1141 ccaccttcaa ccatatgtta attctgatta tagtgtagag ttattttggg ataatcataa
     1201 taataatgcc atcaggccca caaaagaaga gaattttcaa attttcctca aaaaagtcaa
     1261 tgaacgaatt gaagaacgtg gtaaatttat cattaaacaa atttgtgatc aattagatca
     1321 aaaagatttc aatttctata aagaaattga aaatatggat aaaataaaat tttctaatga
     1381 attttaaaaa ggaggatttg tggtcagagt atataaaagt gttcgtctcg catatgaagc
     1441 caaagtatgg atagatgaac ttattcaaaa taaagaacgt aaaatcaaag aactaagtca
     1501 gaataatttt ctaagtacat tagaacaaac acttctatca aatcattacg atgaattaaa
     1561 tggtgtctct ttcaatatag ttttaaaagc ttctatcgga agtgtcattg aagaatcata
     1621 tagaaataca aaacattact ccattgatga atggcaaaaa ctacgtcaag aaatggaaaa
     1681 agacatcaaa aatgtcaatc ctagtctaga aacatccgta actcctagac tctatttaga
     1741 tgaaaatgtt ctaaatggtc ttgatgaatt tcgatatcat ttaatgaaag aagatggtgc
     1801 tactagatta ccaaggctta gttacatcat taaacttgtt gtatattcct attggaagac
     1861 acaacaataa cctaagcagg gtttgcttag gttctctata taaataattg tatagttgtt
     1921 ttaccactta aagaggtttg ttgtttatgt ttaaactaaa aaaagaagct aacttaaaaa
     1981 gaaattattt tattacaagt tcacgtttaa aattgttaca tctgataata attatc
//
LOCUS       DAVLHB010000102         2027 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLHB010000102 DAVLHB010000000
VERSION     DAVLHB010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.102"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..761
                     /locus_tag="VXE36_002100"
     CDS             <1..761
                     /locus_tag="VXE36_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000570495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HEV0780314.1"
                     /translation="KKFRHISLTGDELKYKMEFSNKVWICWFQGEEHAPELIKTCIQS
                     MRNQLQGREIIVLTEKNISDYTEIPDYIIEKYKKGWISRAHYSDILRIDLLCRHGGLW
                     VDATVLNTGGDFSNLEVPLFVYKSLNLSRKDSQAIAASSWLISSYSNHPILLYTRKLL
                     WAYWRRKNSLCNYFLFHICFTIATERYPIEWSAVPTFNNHSPHILHFELNEQFSEKRW
                     EQLKHISAFHKLNHHIDYSSGVNTFYKFIVSSKV"
     gene            766..>2027
                     /locus_tag="VXE36_002101"
     CDS             766..>2027
                     /locus_tag="VXE36_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEV0780315.1"
                     /translation="MSNKISKNLAYNMGYQLIGIAAPLITSPYLSRILGAENLGIHSF
                     TMSVALYFMMFMLLGIANYGNRTIATVKREGKDILSKTFWSIYSIQLIMSILVTIAYL
                     AYLYLGAVHYKVIAILQLFLLLSNAVDITWFFYGLENFKQIVFRNTLVKLLGLFLIFL
                     CVRQGTDLWKYTFINGSVTLVGQLLLWGQLKGILTWKKIQLKELLPHIKPILILFIPV
                     LAISIFTNMDKYMLGLMVDVKQVGFYDNAGRIIEIPKALIAALGAVMLPRTSYLLAEG
                     QKEKSKYYIEVTILYVMIISSVLMFGLISVSDIFSIIFWGEEFLESGRLISAMSPAFV
                     FSVLGNIIRTQYLIPRAKDKDYVVSLIAGAVVNLVLNYFFIKPFGAMGATVSTVLAEF
                     VLSGMQFWSVRRDLDLKRYLKNGLIFYL"
BASE COUNT          651 a          269 c          377 g          730 t
ORIGIN      
        1 agaagaagtt tagacatatt tcgttgactg gagatgagct taaatataaa atggagtttt
       61 caaataaagt ttggatttgt tggtttcagg gagaagagca tgccccagag ttaattaaaa
      121 catgtattca atcaatgagg aatcaacttc aaggaagaga aatcattgtg ttgacagaaa
      181 aaaatataag tgattataca gagattccag actatattat tgaaaaatac aaaaaaggat
      241 ggatttctcg tgcgcattac tctgatatcc ttaggataga tcttctatgt cgccatggag
      301 gattatgggt agatgcaaca gtgttgaata caggaggaga tttctcaaat cttgaggtac
      361 cactttttgt atataaatct ttgaatttat caagaaaaga ttcacaagct attgcagcat
      421 caagttggtt aatttcgtca tatagtaatc atcctatatt actctatacg agaaaactcc
      481 tatgggccta ctggcgaaga aaaaatagtt tatgtaatta ttttttgttc catatatgtt
      541 ttacaatagc tacagagcgg tacccaatcg aatggtctgc tgtccctact tttaataatc
      601 attctcctca tatacttcat tttgagttga atgaacaatt ttcggaaaaa cggtgggaac
      661 aactgaagca tatttcggcg tttcataaat taaatcatca tatagattat tctagcggtg
      721 ttaacacttt ttataagttc atagtatctt cgaaagttta gaaaaatgag taataaaatt
      781 agtaaaaatt tagcctacaa tatggggtat cagttaattg gtattgcagc tcccttgata
      841 acttctcctt atttatcacg gatattaggt gctgaaaatt taggtattca ttcttttact
      901 atgtcggttg cactttactt tatgatgttt atgcttcttg gaattgcaaa ttacggaaat
      961 agaacaattg cgactgttaa acgagaagga aaggatattc tatcaaaaac gttttggagt
     1021 atctactcta tccagttgat aatgtctatt ctggtaacta tagcttatct tgcttatcta
     1081 tatttggggg cagtacatta caaagttatt gcaatattac aactcttttt attgttatca
     1141 aatgctgttg atattacttg gtttttctat ggattagaaa attttaagca aatcgttttt
     1201 aggaatacat tagtcaaact tttaggatta tttttaattt ttttatgtgt gcgtcaaggc
     1261 acagatttat ggaaatacac atttataaac ggatcagtaa ctttagttgg ccaactttta
     1321 ctatggggac aattaaaagg aatattaact tggaaaaaaa ttcaattaaa ggaattacta
     1381 cctcatatca agccaatttt aattcttttt attcctgtac tagccattag tatttttact
     1441 aatatggata aatatatgct tggtttaatg gttgatgtaa agcaggttgg attttatgac
     1501 aatgcaggta gaattattga aattcctaaa gctttgattg cagctttagg ggccgttatg
     1561 ttaccaagaa cttcctattt attagcggaa ggacagaaag aaaagagtaa atactacata
     1621 gaggtaacaa ttttatacgt gatgattatt tctagtgtat tgatgtttgg gctaatatcg
     1681 gtatctgata ttttttccat tatattttgg ggagaagaat ttcttgaatc aggtagattg
     1741 atttctgcta tgtctccggc ttttgtcttc tctgtattag gaaatatcat taggactcag
     1801 tatttgattc ctagagctaa ggataaagat tatgtagtgt ctctaattgc gggggctgtt
     1861 gttaatctag tgctaaacta tttttttata aaaccttttg gtgctatggg agcaacagtt
     1921 agtacagttt tggcagaatt tgtattgtct ggaatgcagt tttggtcagt aagaagagac
     1981 ttagatttaa aaagatattt gaaaaacggt ttgatattct acctatt
//
LOCUS       DAVLHB010000103         1607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLHB010000103 DAVLHB010000000
VERSION     DAVLHB010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.103"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(204..968)
                     /locus_tag="VXE36_002102"
     CDS             complement(204..968)
                     /locus_tag="VXE36_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0780316.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1038..1199
                     /locus_tag="VXE36_002103"
     CDS             1038..1199
                     /locus_tag="VXE36_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0780317.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            1189..1485
                     /locus_tag="VXE36_002104"
                     /pseudo
     CDS             1189..1485
                     /locus_tag="VXE36_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
BASE COUNT          506 a          404 c          304 g          393 t
ORIGIN      
        1 atttcatctc actctaaatc ttaccaacat aaaacgcata gtatcaaagt ttttatcacc
       61 tgatatgata cgtttttctg attttaaaga tttttcccaa cctcaacatg cctaggacaa
      121 gaggaaggtg acctcgttta aacatatttt tgaaaagtat gagctagaca ttttatgata
      181 aaacaaatcc tttgcctgta caactaaagg tggtgaacac ttgctaaact cagttctagc
      241 gccttattaa aagcttccga gccccagtca cgactgtcgt actggtccaa gtccgctaga
      301 gaatctgctg tgaacaacaa ttcaccccag agaaccccac gcaattgagc tactgccgca
      361 agagcagaac actccatctc cacaacagca cagccttctt ccttacgata agccaccttt
      421 tcagccgttt ctcggtaaaa accgtctgtc gtccaggtca tgacttcttc ataaggaatc
      481 cctctgtctt ccaaaacttc ctcaatagca gcaatagcct ctggctgcat ttccatataa
      541 cgacaaggtg ccacatagtg gtaactggct ccctcatctc gcaaagcgcg aacagggact
      601 agaaaggcat tttcctctat atcagctagg acaccacagg tcccagtaga gataatctgc
      661 tccacaccat agccaatcaa ccaatccata aactgggctg ctggagcgga gccaacagga
      721 gcctgagcca gacagacctc ctcacccttg tagttgatga catagactgg ataggtcttg
      781 gtagcagaaa cgaattcgcc aacacagttc gcccctactt ccctcgcata gcggtcaatc
      841 tcctcaccta aaaaagcata gacacacttc tttggcaact gcaaatccaa cccctcgtga
      901 ttgggcatga taaccgcctg aggattatca tcaaactcta aaatgggaat cgcatgtttc
      961 tgaatcatag cccacctcct ctaattttgt actattgtat caaaaactga caaagtgtca
     1021 aggaggaagc tgatgaactg gacaaaaaac aagcctacat cgtcagctgc cacagtggtt
     1081 tgcgcagcta tatcgcagag cctatcctca agcaagcagg atttaccgtc caaaaccttg
     1141 acggcgctta ttcactatac aaaatggcta acccagaagg agtagaatat ggaaactagt
     1201 atcagcatgg ctgactttta tggaaaatac taaaatgaaa atctagaact tatcgatgtc
     1261 cgtgaagcac atgaattcca agcaggacat gcaccaggtg ccaaaaatct tccattaagt
     1321 accttagagc aaggctacaa agaactcaaa cctgaccatg aatactatgt tatttgtcaa
     1381 ggaggagtcc gctctgcatc tacctgccaa tttctcagct cccaaggcct caccgttacc
     1441 aacgtagaag gtggtatgaa tacttggccc ggtcaagtag aataatcaag aggagctggg
     1501 caaaaactca atttcatgag aagatgaagt aatactcaat gaaaattaaa gtgcaaacta
     1561 ggaagttagc cgcaggctgc tcaaaacact gttttaaggt tgtggat
//
LOCUS       DAVLHB010000104         1537 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLHB010000104 DAVLHB010000000
VERSION     DAVLHB010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.104"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..449
                     /locus_tag="VXE36_002105"
     CDS             <1..449
                     /locus_tag="VXE36_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0780318.1"
                     /translation="LYGSSLISFLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLC
                     FSLIHAQESTNQANLIGLQHQVPWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVA
                     LTSVLFALAHHPGTIIAWCLYVSLGMFLGLVRYKLDLWGSMGLHLV"
     gene            684..821
                     /locus_tag="VXE36_002106"
     CDS             684..821
                     /locus_tag="VXE36_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0780319.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT          458 a          221 c          318 g          540 t
ORIGIN      
        1 ttctctatgg ttcgtcactc atttcttttt tatggatgta tggccaacgc aaacaagctc
       61 ataaggtaaa tatgaaatct aggatgaaat ggcttggtat tggattcgtt agcctactga
      121 ttataagtct atgttttagt ctaatccatg cgcaagaaag cacgaatcaa gcaaacttaa
      181 ttgggcttca acatcaagtt ccttggtttt catttttatt gtttttaatc aatgcgagta
      241 tggttgaaga atttctgtat agagaaattt tatggaactt ggttagaaaa ttagatattc
      301 gagttgcgtt gacaagtgtt ttatttgcct tagcacatca tccaggaacc attatagctt
      361 ggtgtttgta tgtatcgctg gggatgtttt tagggcttgt acgctacaaa ttggacttat
      421 ggggcagtat ggggctacat ttggtgtaga acctactagt ttatagtttg ctgctttttt
      481 aaaataggtg acctgatttt taggtaactt ctaaaactaa cttccagttt tgggagagag
      541 atggaagtta ctttgaaaag ttacggaaac attattttct atgtgacaac attgtataat
      601 tgcttgcatt ttactggtgg agagagtata atgagggtgg ataaagtact taatcccaaa
      661 aatttaaata ggaggagcta gctatggcag aagaagtatt aaatcttcaa ttagtatctg
      721 ttcaagttga cgaaacagat gaagttgatg gaatgcgatt tagtacattc agtacaaatc
      781 gttgcggtaa ctggagtgct tttagttggg aaaattgtta attcatttaa attgtaaact
      841 ttagagattc tctggagtta tggatgtcgt tccaatatgt gcacgttgga atgttagtgc
      901 ttatatgggg ggaacagaat cctctcttga ttgaagacaa gctagtcatt aggctggttt
      961 gtctttttgt caactgtagt gggttgatat aatagtatta gtgagtggga taaaagtttc
     1021 atttagttta ttcagtacaa atttaacggg tcaagattta tatactagtg gtgtttttgg
     1081 ggctgagaga agtatcttga ttttatgtgt ggtttttata cttacagttg ttctgctcca
     1141 aagagcttgt agagaagaat tagctcataa aggagattga ttattttgat atcaaaaaaa
     1201 tgcacaggat aacctgatgc atttttttag cgacaatgct tgctacttcc ttctgtcgaa
     1261 tttagacaat tttaaacccc aattattcac cccaaatcta aaaaccatcc agaatccttg
     1321 ccttagctta gatcctggat ggtttctttt ttcacccaat gggtgttttt tactagacaa
     1381 aaaagagttt cccctttatg gtataagtgt agaaaaaaac acaaaaagaa aggaaactca
     1441 catgaacagt ttaccaaatc atcacttcca aaacaagtct ttttaccaac tatctttcga
     1501 tggaggtcat ttaacccagt atggtggtct tatcttt
//
LOCUS       DAVLHB010000105         1244 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLHB010000105 DAVLHB010000000
VERSION     DAVLHB010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1244
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.105"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..151)
                     /locus_tag="VXE36_002107"
     CDS             complement(<1..151)
                     /locus_tag="VXE36_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV0780320.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEEL"
     gene            complement(164..913)
                     /locus_tag="VXE36_002108"
     CDS             complement(164..913)
                     /locus_tag="VXE36_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0780321.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKIYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            complement(925..>1244)
                     /locus_tag="VXE36_002109"
     CDS             complement(925..>1244)
                     /locus_tag="VXE36_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780322.1"
                     /translation="NSVPGTTHLFSCLNIQILVKIILYIFRYNSCMKIFNFRDKELIF
                     FNKIVNGLIQNIEENLEDDIERILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFL
                     DKL"
BASE COUNT          442 a          229 c          128 g          445 t
ORIGIN      
        1 taagctcttc atttttagat ggaagaatgc ccttttttaa attatttatt tttacagaat
       61 ctatatcata tgcaacaact ttatatttag atgcaaatag taacgcgtag gccagcccaa
      121 catgccccaa accaattact gctatattca taaaactact tccttatttc ttaatccaaa
      181 atctaataga ataagctgcc ccattcctta aatacaactc tttaatattg tttaaaagtt
      241 tttcaactga tttccagatt atcaaaatct gagatttata gcacaatatt gatgatattc
      301 tatcaatata atgtttttca tcaagttcct cttgatatat ttttaattct ttagtttttc
      361 ccatataact aaccatacta ctatcactta catatgggaa atcctcataa tatattactt
      421 tataacgcat aaattcaagc gcccttccaa tactattcac aaaaacatga tcaacatggt
      481 caccaagtga aagcggacaa tatacgacac atttgtcgtc taaatgcatt aacagctctt
      541 ttatgatatc attctttaat gtgtcctcat tttttaattc actatagata tgacggtata
      601 gaaaattgcc atttctatct ttcctataga gacattcata gtacgataag tgtctaaaat
      661 cacattgtag acgttcacaa gctaacctgt cttctttctt cctttcttca atcggatatt
      721 tcccaaggtt acacaactta tgaaattgct tagcagaggg ctgtagctgt tggctcaaag
      781 ggtaaccaga aaatatagta ataacaagta caatttctcc ttctgaagtt aattttgaaa
      841 tataatcacc acaggaaaaa attgcgtcat ctaaatgtgg agataaaaag atatacttag
      901 tattgttact cataaccatt ccctctacaa tttatctaaa aactcactaa gtgtctgatt
      961 aaattccaca tcatcaaaaa aattcacctt attcttaata atgaatattt cgttaaataa
     1021 acatatatat aaatatttca atatcctttc aatatcatcc tctaaattct cctcaatatt
     1081 ttgtatcagc ccatttacaa tcttattaaa aaagataagc tctttatctc taaaattaaa
     1141 tattttcata caactgttgt atcgaaaaat atataaaata atttttacta atatttgaat
     1201 atttaaacaa ctaaataaat gagttgtacc cgggacacta ttta
//
LOCUS       DAVLHB010000106         1113 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLHB010000106 DAVLHB010000000
VERSION     DAVLHB010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1113
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.106"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..325)
                     /locus_tag="VXE36_002110"
     CDS             complement(<1..325)
                     /locus_tag="VXE36_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780323.1"
                     /translation="MGTWKPSREERVKIGIETFKNHPIDKSFNEYYLEVRKHVETCLK
                     PLSELPGYEASNIKYHILNVDLSKQKDFTTKVGECLFVQFTEDGHIVVIGAGHDYGMT
                     TSNKYI"
     gene            complement(372..767)
                     /locus_tag="VXE36_002111"
     CDS             complement(372..767)
                     /locus_tag="VXE36_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780324.1"
                     /translation="MEIYTYSDFLKDKTALTFEEAGEIYNNLVSSLNTKDPDFLENWT
                     TLIELAAQYTELRVRSETIPLPKREQNDISRKSTHKAFISQLKVIKYFSENDGKNTNW
                     FDQITNDRQRQGDFANYLAYIYSVNTRKK"
BASE COUNT          357 a          159 c          150 g          447 t
ORIGIN      
        1 caatatattt attagatgtt gtcattccgt aatcatggcc tgcgccgata actacaatat
       61 gcccatcttc tgtaaattgt acaaataagc actccccaac tttagttgta aagtcttttt
      121 gtttagatag atccacattt aaaatgtgat atttaatatt tgatgcttca taaccaggta
      181 gttcacttaa aggttttaag caagtttcga cgtgttttct aacctctaaa tagtattcat
      241 tgaaactttt atctattgga tgatttttaa atgtctcaat accaattttt actcgttctt
      301 ctcggcttgg tttccatgtt cccataaaat cctcccattg aaaatatata atcaattaaa
      361 attttttata tttatttttt tctagtattt acagagtaaa tatatgctaa ataatttgca
      421 aaatctccct gacgttgtct atcatttgtg atttgatcaa accaattagt attttttccg
      481 tcattttcag agaaatattt aataactttt aattgactta taaaagcttt atgagtagat
      541 tttctggaaa tatcattttg ctctctcttt ggcagtggaa ttgtttcaga cctgactcga
      601 agttctgtat attgcgctgc taattcgatt aacgttgtcc agttttcaag aaaatcagga
      661 tcttttgtat tcaaagagct cactagattg ttatatattt ccccagcttc ttcaaaagtt
      721 aatgcagttt tatctttcag aaagtctgaa taagtgtaaa tttccataaa gggcctccac
      781 aaaaaaaata ttttttgtct aaatacgact atacttttat tataattcta tctaaaaata
      841 atgtcaagga ttttcgtaaa aaaattttaa ttagttttac aaaagtattg cgcaatagga
      901 tgttaagttt tgatatttgt agtataatta gtactgactg atttcatcaa ttagggcaaa
      961 tttctgagat atctgactcg tattttttta ttggataaaa aatttgccct atttgaatga
     1021 aattatttaa aaatagataa aatttaattg ataattgatt gtaaaaaagt ccgtgtttat
     1081 aactatttgt gatattttaa tttaatagtt agc
//
LOCUS       DAVLHB010000107          997 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLHB010000107 DAVLHB010000000
VERSION     DAVLHB010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..997
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.107"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..>997)
                     /locus_tag="VXE36_002112"
     rRNA            complement(<1..>997)
                     /locus_tag="VXE36_002112"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          215 a          315 c          205 g          262 t
ORIGIN      
        1 agggatgtca agacctggta aggttcttcg cgttgcttcg aattaaacca catgctccac
       61 cgcttgtgcg ggcccccgtc aattcctttg agtttcaacc ttgcggtcgt actccccagg
      121 cggagtgctt aatgcgttag ctacggcact aaaccccgga aagggtctaa cacctagcac
      181 tcatcgttta cagcgtggac taccagggta tctaatcctg tttgctcccc acgctttcga
      241 gcctcagcgt cagttacaag ccagagagcc gctttcgcca ccggtgttcc tccatatatc
      301 tacgcatttc accgctacac atggaattcc actctcccct cttgcactca agttaaacag
      361 tttccaaagc ctactatggt taagccacag cctttaactt cagacttatc taaccgcctg
      421 cgctcgcttt acgcccaata aatccggaca acgctcggga cctacgtatt accgcggctg
      481 ctggcacgta gttagccgtc cctttctggt aagataccgt cacagtgtga actttccact
      541 ctcacactcg ttcttctctt acaacagagc tttacgatcc gaaaaccttc ttcactcacg
      601 cggcgttgct cggtcagact tccgtccatt gccgaagatt ccctactgct gcctcccgta
      661 ggagtctggg ccgtgtctca gtcccagtgt ggccgatcac cctctcaggt cggctatgta
      721 tcgtcgcctt ggtgagccgt taccccacca actagctaat acaacgcagg tccatctggt
      781 agtgatgcaa gtgcaccttt taagcaaatg tcatgcaaca tctactctta tgcggtatta
      841 gctatcgttt ccaatagtta tcccccgcta ccaggcaggt tacctacgcg ttactcaccc
      901 gttcgcaact catccagaga agcaagctcc tccttcagcg ttctacttgc atgtattagg
      961 cacgccgcca gcgttcgtcc tgagccagga tcaaact
//
LOCUS       DAVLHB010000108          954 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLHB010000108 DAVLHB010000000
VERSION     DAVLHB010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.108"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..907)
                     /locus_tag="VXE36_002113"
     CDS             complement(<1..907)
                     /locus_tag="VXE36_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0780325.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSL"
BASE COUNT          392 a          156 c          104 g          302 t
ORIGIN      
        1 taagtgataa agtatagtct tttataacaa ttgctactaa ccaacttgag ccgttcaaaa
       61 aaagaaatac accaacaatt tgattcgatt ttaaatattt tattacgatt ggcgctagca
      121 tatttcccaa tataccaccc aaaccagcaa tagttaaaaa aataccataa aaaatcggac
      181 catcaaaata tcgaatagaa aaaatcggta caactactgt ctgaaatgaa taaaaaaagt
      241 ttataagcgt taaagaaata ctggttttaa ataataattt attatttaaa ataaactttg
      301 taccttgcaa cacttctctc ttgtaatatt tgaaagagaa gttttctata ttcgcattgc
      361 tagttctaaa ttttaacaac aacaatataa atagagcaag taaaaatatg cctatatcta
      421 tcttaaccaa taaaataaat cctactgcca cctgtaaaaa tgatgcgaat gaattaaaaa
      481 tagaatctaa tactttatac gaaatactaa aaagagaatt tgcaaataca atcttatcat
      541 attctaccac ttgaggaatc aacacatctt ctatcacgta acttatggag ctagccatta
      601 ctgaaataaa cactagactc attatcaccc aaaatgatat ttggtttaat aataataaaa
      661 atattacagc cactgctaat tgaaccaaaa ttgatattat aagaattttt tgcggattta
      721 ctctgtcaat aactggtcca aaaaagatta gtaacaaatc cggtagataa tttactgcaa
      781 taaatattcc taagaacatg ctcgaagaat aattattgct aacgtgccac aatgctacta
      841 tataaaatac actgtctgct aagttaacaa tcaatctaat tattagcaac tttatcaaat
      901 ttttcatcta ttaacctcat cagtagtttt taaatattca tttgaaaaag attt
//
LOCUS       DAVLHB010000109          929 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLHB010000109 DAVLHB010000000
VERSION     DAVLHB010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.109"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(147..293)
                     /locus_tag="VXE36_002114"
     CDS             complement(147..293)
                     /locus_tag="VXE36_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780326.1"
                     /translation="MKTKEQTRKLAAGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FKEY"
     gene            451..669
                     /locus_tag="VXE36_002115"
     CDS             451..669
                     /locus_tag="VXE36_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0780327.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
BASE COUNT          294 a          142 c          180 g          313 t
ORIGIN      
        1 ttattacctt gaacgacatg cgttaaaagt tagttgaacc gccgtatgcc gaacggcacg
       61 tacggtggtg tgagaggggc tagagattat cccctactcg atttcgaaat ctagtggaat
      121 gaatctggaa tagtccatcg agctttctaa tactctttga aaatctcttc aaaccacgtc
      181 aacgtcgcct tgccgtgcgt atggttactg acttcgtcag ttctatccac aacctcaaaa
      241 cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttggtttt cattgagtat
      301 aacacattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt taccttcgat
      361 atattatatc ccatagttaa ggttggtcat acagatgatt atagccatgg agccgtaaaa
      421 cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac tgtaatagga
      481 tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa tggtactgct
      541 attctttatc cttatttacg ttctattgtt tcaatagttt cggcaattga tagcagtgaa
      601 gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca accttttgaa
      661 gaagaataat ttattagctc actaaattga gggtaaggaa aagtaaaagc agtaagaaaa
      721 atgtcttgca ttatacagca actttttggg aatgagtaga tggattgaat aaaatttgat
      781 taagagtgga tgatttatct gtagattatt attggacagt tagtcttgaa gtagtctaag
      841 aattaggtta taatcagtag aagccttgct aataatgagg aggttagttt atgtatagta
      901 gactgaatct aaaatagtac gaaacaatt
//
LOCUS       DAVLHB010000110          883 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLHB010000110 DAVLHB010000000
VERSION     DAVLHB010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..883
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.110"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            1..883
                     /locus_tag="VXE36_002116"
                     /pseudo
     CDS             1..883
                     /locus_tag="VXE36_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
BASE COUNT          316 a           82 c          185 g          300 t
ORIGIN      
        1 cttatacact gtcatggcta ctcaactaat tattttttat atatgttaaa aaaacttgac
       61 aagaatggat ttggaaaggt taagacagtg ataacatgcc atggatgggt tgaatataac
      121 ttaaaaaaga aattcttgac ttattttgat ttttggacat attctatggg agatgctttt
      181 atttgtgtat ctgaaactat gaaaaaaaag attggagagt ataataaaaa ataagaagat
      241 agttgcaata aataacggaa ttaatgtatc aaatagcgat ttagatgtag taggtgttca
      301 agactttaaa aaagaatttt gtattccaaa taacaaaaaa tcatttgtta tgttggaagg
      361 ttggatccag aaaaaaggcc ggatagattc cttgaatttg cagaaaaatt atttttagtc
      421 agagaagatg tgatttttat tatggctgga aatggtagta tgtgggctgc tttgaaagaa
      481 aaaatttgcc atttgaaatg tagagataat ttcaggttac ttggtgaaat ctatccagct
      541 actatagttt accaaatatc ggatttattg tatattcctt ctgatacaga aggaatacct
      601 atgtgtgttt tagagtcaat gtcacaagga actccggttt tagctagtaa tgttggcggg
      661 ttaagtgaaa ttattgaaca tagggttgat ggatttttat ttgagaagga agatgttgag
      721 ggagtgtgtg cttgtgctaa ttttttactc aatgattctg agtatttgaa atatataggt
      781 gagaatagta aatcaaaaat aagaaaacat ttttctgtgc aaaaaatgtt tgtagaaacc
      841 atgagagtat atgatgaatt attagagaag agtagtcatg gat
//
LOCUS       DAVLHB010000111          819 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLHB010000111 DAVLHB010000000
VERSION     DAVLHB010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.111"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            46..>819
                     /locus_tag="VXE36_002117"
     CDS             46..>819
                     /locus_tag="VXE36_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0780328.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERK"
BASE COUNT          267 a          173 c          134 g          245 t
ORIGIN      
        1 gatctataat gaaaagcgat caaacaactc attagaaaga ttcatatgga acaattacat
       61 tttatcacaa aactactcga tatcaaagac acaaatatcc aaattataga tgtcgtcaat
      121 agggattcac acaaagaaat catcgccaaa ctggactacg acgcaccatc ttgccctgat
      181 tgtggaagtc taatgaagaa atatgacttt caaaaaccgt ctaagatccc ttacctcgaa
      241 acaactggta tgccttctag aattctcctt agaaaacgcc gtttcaagtg ctatcactgt
      301 tcaaaaatga tggttgctga gactcccctg gtaaagaaaa atcaccaaat ccctcgtatc
      361 atcaaccaaa aaattgctca aaagttaatt gaaaaaattt ctatgactga tattgcccat
      421 cagctggcca tttcaacttc aactgtcatt cgcaagctca atgactttca ctttgagcat
      481 gatttttctc ggcttccaaa gattatgtct tgggatgagt atgccttcac taagggaaag
      541 atgagtttca ttgcgcaaga ttttgataat cttaatatta tcactgttct tgaaggcaga
      601 acacaagctg tcatccgaaa tcactttctt cgctacgata gagccgttcg ttgtcaagtg
      661 aaaatcatta cgatggatat gtttagtcct tactatgact tggctaaaca gctttttccg
      721 tgtgctaaaa tcgttctaga tcgtttccat attatccaac atctcagccg tgccatgagt
      781 cgttttcgtg ttcaaattat gaatcagttt gaacgaaaa
//
LOCUS       DAVLHB010000112          800 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLHB010000112 DAVLHB010000000
VERSION     DAVLHB010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.112"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            407..>800
                     /locus_tag="VXE36_002118"
     CDS             407..>800
                     /locus_tag="VXE36_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEV0780329.1"
                     /translation="MNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYFVEFE
                     FIIADKLSEYNMVSGSYDWFLTLIDYMEI"
BASE COUNT          297 a           86 c          140 g          277 t
ORIGIN      
        1 atataatttg ccgtctaata tcacccaatc taagggattt aaaatacacc tgagcgcttc
       61 aatattaaat gctaatttgg ttgctaaaaa attctttgat tttatatttt ctagagagaa
      121 gaagataaat ttcaaaattt tggttagcat taaagaactt tctttgcaaa atacagggct
      181 taatggttat tcacaagtcg ggaaattcat tacaatttat ccaaaagata ataaagagtt
      241 tcaacgtttg ttacacaaat tagaaatatt gtataaaggt gtaaagggtg taaacatacc
      301 atcagatttc agatttcaac ttagcgaggt tgtatattac agatatgggg agttcgtaaa
      361 agatagcact ttcaaggata aaagagataa gaaaatccct tcaaatgtga atgttccaat
      421 aagggattac tatattccaa gatataacac tattcctgat caatatatta ttttggaagt
      481 gatttctaaa aatgccaaag gtggagttta taaagtattt aatactcaaa agcgagttta
      541 ttctttatta aaagaagcta gtgatttatc gttggttgat tttacaaata gagattctgt
      601 gaatcgttta ataaatgaaa gagaaatatt agtagaattg gaaaaggagg aatttactcc
      661 aaaagttttt aacgattttt acataaagaa ttcgtatttt gtggaatttg agtttattat
      721 tgcagataaa ttaagcgagt ataatatggt tagtggctcg tatgattggt ttttaacatt
      781 aattgattat atggagataa
//
LOCUS       DAVLHB010000113          771 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLHB010000113 DAVLHB010000000
VERSION     DAVLHB010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.113"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..105)
                     /locus_tag="VXE36_002119"
     CDS             complement(<1..105)
                     /locus_tag="VXE36_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0780330.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDT"
     gene            complement(108..338)
                     /gene="blpU"
                     /locus_tag="VXE36_002120"
     CDS             complement(108..338)
                     /gene="blpU"
                     /locus_tag="VXE36_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0780331.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(407..676)
                     /gene="blpJ"
                     /locus_tag="VXE36_002121"
     CDS             complement(407..676)
                     /gene="blpJ"
                     /locus_tag="VXE36_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV0780332.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLVGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
BASE COUNT          245 a          196 c           85 g          245 t
ORIGIN      
        1 tgtatccttt ttgggaaatt ttgaaaatat ttttctaatt aaattatcca tataaggacc
       61 aaatatacca actactaaac caataataaa acttttaaaa tccataatta ccaccaacat
      121 gttgctgcat aggctacacc tccaagtata gctccacccg cagcaccagt tgctgcacct
      181 tgccatgttc ctgttttaat gcctagttga agacctcttg ctgctcctcc tccaacacct
      241 gctttggcaa aatctcccca attgcatccg ccaccttcaa cgcaagcaag catttcagta
      301 tccataacag aaaattgtga catcattttt gtatccatga caaatactcc ttttttaaaa
      361 aactaaaata aatcagaata gaatcctcat aattttacta taagtcttac caacttagtc
      421 ccaatttatc accaaccata cctcctaagc atgttaatcc acccccaatt gcaccaatgt
      481 gtgctccaac aaatgcacca acaagtccag ctactcctaa agtggccaaa cctgctccag
      541 ttccaccagt tataattccc gtagtgactc ctgtaatcag tgcattttga caatcagtgg
      601 agctataccc cccttcaact ttcgcaagca tttcagtatc cataacctct aactgtgaca
      661 acatttttgt attcatgatg aatacctcct ttttattttc aatttgttac caaagtctta
      721 aattcaataa acaaatagat tttttatagt atctttttga ttttcttaaa a
//
LOCUS       DAVLHB010000114          761 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLHB010000114 DAVLHB010000000
VERSION     DAVLHB010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.114"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            477..728
                     /locus_tag="VXE36_002122"
     CDS             477..728
                     /locus_tag="VXE36_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780333.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
BASE COUNT          281 a           80 c          145 g          255 t
ORIGIN      
        1 gtgataaaat aaatgcaaga aaacgaaagg agaggtatat gagaagtttg tttaggaaaa
       61 ttgttgcttt gttagtcata ggattaatcc tattagggac tgctggagga actcaagttc
      121 ataagatggc tagagggatt gatccaggtc ctgcgaatgg tatttataga taggagatta
      181 tagtcactta aaaatcaaaa aattataaaa tttttgtttt acttaaatag atattttatg
      241 atgggcgaag tttttataac tagttcctat aagtacagaa acctatttta atttactaat
      301 ttcaaaacaa ttttttgaga tatatgtaat taaatctaaa ttaagcttta aaaaattatt
      361 tttagcaatt tgattttgaa agtgtcatgc agcaatatga aagcgtagaa tagaggtgtt
      421 tccaatgtac aagtaagttt tgattccaaa taaagtaata gaaaaggagc tatataatga
      481 gtagtcaaat gaaagctttc ttgaatgaac ttcaaggaaa tatggaagtt gttggagaat
      541 tttttgataa tcctgaaaag gtaattagaa aatttggaat tgtcggaaga gagaaggaag
      601 cattgctaat ccgtgactta aatgatatgg atgattatgc tctttcaatt caaaatagcg
      661 ttgcatcgcc ttctggggca catagtagca cttgccattt tgttagacaa gatttacaat
      721 ccgcataatt gttaatatat aaaacataaa atttcaattt t
//
LOCUS       DAVLHB010000115          688 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLHB010000115 DAVLHB010000000
VERSION     DAVLHB010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.115"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            <1..618
                     /locus_tag="VXE36_002123"
     CDS             <1..618
                     /locus_tag="VXE36_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0780334.1"
                     /translation="PYLKEGGEYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSNG
                     RGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNELR
                     LGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRFAIASVMCKTSPFVFFDEPS
                     SGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          271 a           79 c          125 g          213 t
ORIGIN      
        1 ccttatttaa aagaaggtgg agagtatcag ataaaaaatc ttagctacaa atttactgat
       61 gatgagtgtt taagcttaaa agatatttca ttcaagcttg ggaaaattta tggcataata
      121 ggatccaacg gacgaggaaa atcaacgctt ttaagatgtt taataggtct tgagaaaaaa
      181 tcaaaagaag aaatttattt taagggagag aagctatcta aaaaagaaag actcaaaaac
      241 tcttcacttg ttatgcaaga tgtaaatcat caattattca cagatgaagt attcaacgag
      301 cttagattag gagtaaagaa ttttgatgaa gaaaaggcga aaatcatttt aaaagattta
      361 ggcctggacg aatttattga aaggcatccg atgagtttat caggagggca aaagcaaagg
      421 tttgcaatag catctgttat gtgcaagact tctccatttg tcttttttga cgaaccttca
      481 agtggtatgg attattccaa tatgataaaa atatctgaac tgattaataa gtataaaacc
      541 atggataaaa taatttttat tgtttcccat gatatagaat ttttaaatga agtggcagat
      601 gaaatttttg aattgtaaaa tagagtctgt taaacatgtc tatagaacta gtaaattgtc
      661 taaaaattta aaagatacta acacatat
//
LOCUS       DAVLHB010000116          663 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLHB010000116 DAVLHB010000000
VERSION     DAVLHB010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.116"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..646)
                     /locus_tag="VXE36_002124"
     CDS             complement(<1..646)
                     /locus_tag="VXE36_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0780335.1"
                     /translation="MLAEAEALVEADSDAEILAEADALVDAEAEALVDAEVDALVLAE
                     ADALVLAEADALVDAEADALVLADVDALVEADSDAEVLAEAEALVLAEADALVDAEAE
                     ALVDAEVDALVLAEAEALVLAEADALVDAEAEALVLAEADALVLAEAEALVDAETEAL
                     VDAEADALVDAEAEALVLAEADALVLAEADALVEAEADALVEAEADALVLAEADA"
BASE COUNT          161 a          217 c          155 g          130 t
ORIGIN      
        1 gtgcatcagc ttcagcaagt acaagtgcgt cagcttcagc ctcaacaagt gcatcagcct
       61 cagcctcaac aagtgcatca gcttcagcaa gcaccagtgc gtcggcttca gcaagtacta
      121 gcgcctcagc ttcagcgtca acaagtgcgt cagcttcagc atcaacgagt gcttcagtct
      181 cagcgtcaac cagtgcctcg gcttcagcaa gcaccagtgc gtcggcttca gcaagtacta
      241 gcgcctcagc ctcagcatca accagtgcgt cagcctcagc aagtaccagt gcttcggctt
      301 cagcaagtac cagtgcatca acttcagcgt caacgagtgc ttcggcttca gcatcaacga
      361 gtgcgtcagc ctcagcaagt accagtgctt cggcttcagc aagcacctca gcgtctgaat
      421 cggcctcaac gagtgcgtcg acatcagcaa gcaccagtgc gtcagcttcc gcatcaacga
      481 gtgcgtcagc ctcagcaagc accagtgcgt cggcttcagc aagtacaagt gcatcaactt
      541 cagcatcaac gagtgcctca gcctccgcat caacgagtgc gtcagcctca gcaagtatct
      601 cagcgtctga atcggcctca accagtgcct cagcttcagc aagcaccagt gcatcggctt
      661 cag
//
LOCUS       DAVLHB010000117          568 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLHB010000117 DAVLHB010000000
VERSION     DAVLHB010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.117"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            51..248
                     /gene="blpI"
                     /locus_tag="VXE36_002125"
     CDS             51..248
                     /gene="blpI"
                     /locus_tag="VXE36_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV0780336.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
BASE COUNT          210 a           60 c          101 g          197 t
ORIGIN      
        1 tcaaagttac aacaagacaa aaataaaaaa agaaaaaagg agtatttgtc atgaatacaa
       61 aaatgatgga acaattttct gttatggata atgaagaact cgaaatagtt agtggaggaa
      121 gaggcaattt aggatctgca atcggtggtt gtattggagc agtactatta gctgctgcga
      181 ctggtccgat aactggggga gcagcaacac ttatttgtgt aggttcagga attatgtcct
      241 ctttgtaaga ttatgattct taaatatagt attattatcg ctattaattt actgtcttat
      301 ttacttactt acaaaatatc aaagttatct aagaatgatg agaataagat agttagcaaa
      361 attttaatta tattatcaat cgtttatgta atcgttgatg ctttacttag ttgatggatt
      421 ggtaggaata aaaaacttaa ctataaacta ttatttacta atattttttg ctttctgcaa
      481 gttaataaat agtatagtaa aactttttat tgcaaggaga ataacgaaat taagatattt
      541 tagatactca agattattga aatcttag
//
LOCUS       DAVLHB010000118          557 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLHB010000118 DAVLHB010000000
VERSION     DAVLHB010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.118"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..>557)
                     /locus_tag="VXE36_002126"
     CDS             complement(<1..>557)
                     /locus_tag="VXE36_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV0780337.1"
                     /translation="KLKERISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYAC
                     KELSADAYFPKLLEGGQLASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQ
                     LIVDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEE
                     ADSFITPILERFNQLLFRMDSGFAT"
BASE COUNT          176 a          110 c          126 g          145 t
ORIGIN      
        1 ggtcgcaaag ccactatcca ttcgaaagag aagttgatta aaccgttcta aaataggtgt
       61 gataaagctg tctgcctctt cagaacaata acgattacca ggacgaagct gggcattgaa
      121 acaataacct gtcttcccct cgaaagcata aagaggatga tagccatgag cacgatagtg
      181 ggcgttataa gcaacacctt cttgcttgcc ataagttgtg aaatgggtag aatcgatatc
      241 tacaatgagt tggtttagct ggtgaaactg taaaaagaat tcgaccaatt caaggttgag
      301 gcatcgcaaa ctatggactg tttcctcgtc agttctggaa agaaaacggg ataaggttgg
      361 ctgtgaagca agctgccctc cttccaacaa ttttggaaag taggcatcag ctgacaattc
      421 tttacaagca tagtccgttc catagcctgt taacagttga aagaggaact ggacaaggat
      481 atctgaatcc gaataacgac agtagcggcg ttggtcattc gttactaaat acttagaaat
      541 ccgctctttt agtttca
//
LOCUS       DAVLHB010000119          549 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLHB010000119 DAVLHB010000000
VERSION     DAVLHB010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.119"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            23..>549
                     /locus_tag="VXE36_002127"
     CDS             23..>549
                     /locus_tag="VXE36_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV0780338.1"
                     /translation="MTEEKFQKIIQSKDTETLAFILESTPYHLSIDILEDPSQTEISL
                     MTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLKSKAAIKKDFSKLLIPIGIFD
                     IESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIRVLDVGADLAYFKHLKLLSNE
                     LDEVLSQVIVEMIDF"
BASE COUNT          189 a           73 c           89 g          198 t
ORIGIN      
        1 ttcggtaaaa gaaaacgatt ttattacaga agaaaaattt caaaaaatta tacaatccaa
       61 agatacggag acattggcat ttatcttaga atcaactccc tatcatttat cgattgacat
      121 cttagaagat cctagtcaga cagagatttc gctaatgaca aaattagtca atgattatag
      181 atgggcctat gctgaaagtc cgtctgatat aattgtgact ttatttgctt tacgatatgt
      241 ttatcataat atcaaagttt tattaaaatc taaggcggca attaagaaag atttttctaa
      301 attattaatt ccaataggga tttttgatat agaaagttta aaacatttag tttcttcctt
      361 acattcagat acacttcctg attttatggt tcgtgaagta gaatcaattt ggaatgagta
      421 tgaaactttt aataatattc gtgtacttga tgtcggagct gatctagcat attttaaaca
      481 tctgaaactt ttatctaatg agttagatga ggtactgtct caggttattg tcgaaatgat
      541 tgactttta
//
LOCUS       DAVLHB010000120          469 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00065172
            SAMN33606898-rid17936423.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLHB010000120 DAVLHB010000000
VERSION     DAVLHB010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606898
            Sequence Read Archive: SRR23725966
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721843.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721843.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:16:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,128
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 63 of 126
            Pseudo Genes (incomplete)         :: 59 of 126
            Pseudo Genes (internal stop)      :: 37 of 126
            Pseudo Genes (multiple problems)  :: 27 of 126
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606898-rid17936423.denovo.122"
                     /strain="AUSMDU00065172"
                     /serotype="15B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST8711"
     gene            complement(<1..154)
                     /locus_tag="VXE36_002128"
     CDS             complement(<1..154)
                     /locus_tag="VXE36_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEV0780339.1"
                     /translation="MVTKDKGLTYNSTLHAIKVLACFSVVAIHIWLPGKIGAFYQIIA
                     RFAVPMF"
BASE COUNT          172 a           98 c           38 g          161 t
ORIGIN      
        1 agaacattgg aactgcaaat cgtgctatta tttgataaaa cgctccaatt tttcctggta
       61 gccatatatg aatagcaaca acactaaaac atgctaatac ttttattgca tgcaaagtac
      121 tattatatgt taatccttta tctttagtaa ccatctttcc tacctattta acaaaataca
      181 tttcccaaaa tcaaacctgt cactcaaaac aataaaaaaa tagttcctaa cttattttat
      241 tattttccaa atcatctaaa tatctgatat aatcaaacct aaactctagc tgtaacttac
      301 tcaaaatgtc atatcaatcc cttataatga cccctagctc catctaagaa atgagtactc
      361 acattattcg ttaactacac tgcaccgata ttcttacttt aataatgaag ctataatata
      421 gcttagttta tctctataat ctctataatc tcaattacca aagtttcaa
//
